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Conserved domains on  [gi|111494230|ref|NP_001036081|]
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phosphatidylinositol N-acetylglucosaminyltransferase subunit Y [Homo sapiens]

Protein Classification

PIG-Y family protein( domain architecture ID 10633514)

PIG-Y family protein similar to phosphatidylinositol N-acetylglucosaminyltransferase subunit Y (PIG-Y) that is part of the complex that catalyzes the transfer of N-acetylglucosamine from UDP-N-acetylglucosamine to phosphatidylinositol and participates in the first step of GPI biosynthesis, and may act by regulating the catalytic subunit PIGA

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
PIG-Y pfam15159
Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y; This family of proteins ...
41-70 1.33e-03

Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y; This family of proteins represents subunit Y of the GPI-N-acetylglucosaminyltransferase (GPI-GnT) complex. It may regulate activity of the complex by binding the catalytic subunit, PIG-A. This family includes the ERI1 subunit found in yeast, such as Swiss:P62651.


:

Pssm-ID: 464537  Cd Length: 70  Bit Score: 33.38  E-value: 1.33e-03
                         10        20        30
                 ....*....|....*....|....*....|
gi 111494230  41 CFYSLLLPITIPVYVFFHLWTWMGIKLFRH 70
Cdd:pfam15159 41 DYYCYLVPLTIPVTWVFVIANWVGWKYFRH 70
 
Name Accession Description Interval E-value
PIG-Y pfam15159
Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y; This family of proteins ...
41-70 1.33e-03

Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y; This family of proteins represents subunit Y of the GPI-N-acetylglucosaminyltransferase (GPI-GnT) complex. It may regulate activity of the complex by binding the catalytic subunit, PIG-A. This family includes the ERI1 subunit found in yeast, such as Swiss:P62651.


Pssm-ID: 464537  Cd Length: 70  Bit Score: 33.38  E-value: 1.33e-03
                         10        20        30
                 ....*....|....*....|....*....|
gi 111494230  41 CFYSLLLPITIPVYVFFHLWTWMGIKLFRH 70
Cdd:pfam15159 41 DYYCYLVPLTIPVTWVFVIANWVGWKYFRH 70
 
Name Accession Description Interval E-value
PIG-Y pfam15159
Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y; This family of proteins ...
41-70 1.33e-03

Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y; This family of proteins represents subunit Y of the GPI-N-acetylglucosaminyltransferase (GPI-GnT) complex. It may regulate activity of the complex by binding the catalytic subunit, PIG-A. This family includes the ERI1 subunit found in yeast, such as Swiss:P62651.


Pssm-ID: 464537  Cd Length: 70  Bit Score: 33.38  E-value: 1.33e-03
                         10        20        30
                 ....*....|....*....|....*....|
gi 111494230  41 CFYSLLLPITIPVYVFFHLWTWMGIKLFRH 70
Cdd:pfam15159 41 DYYCYLVPLTIPVTWVFVIANWVGWKYFRH 70
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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