NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|1859470316|ref|NP_001035928|]
View 

transmembrane protein 80 isoform 2 [Homo sapiens]

Protein Classification

transmembrane 17 domain-containing protein( domain architecture ID 10561172)

transmembrane 17 domain-containing protein similar to Homo sapien transmebrane 17 protein, which is part of the tectonic-like complex, a complex localized at the transition zone of primary cilia and acting as a barrier that prevents diffusion of transmembrane proteins between the cilia and plasma membranes

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
Transmemb_17 pfam09799
Predicted membrane protein; This is a 100 amino acid region of a family of proteins conserved ...
 21-127 3.94e-24

Predicted membrane protein; This is a 100 amino acid region of a family of proteins conserved from nematodes to humans. It is predicted to be a transmembrane region but its function is not known.


:

Pssm-ID: 462907  Cd Length: 107  Bit Score: 89.56  E-value: 3.94e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1859470316  21 MLFYLSGTYYALYFLATLLMITYKSQVFSYPHRYLVLDLALLFLMGILEAVRLYLGTRGNLTEAERPLAASLALTAGTAL 100
Cdd:pfam09799   1 MLLYFNSYYFPLWFLAELLLLIYKGINLPYPGNYLALDVVLLVLLAILEVLRLYLGYKGNLTEKVPPLAAFLLLTLPSQL 80

                          90       100
                  ....*....|....*....|....*..
gi 1859470316 101 LSAHFLLWQALVLWADWALSATLLALH 127
Cdd:pfam09799  81 PLVYLLLLQTYVLRLEYILNAILLALL 107
 
Name Accession Description Interval E-value
Transmemb_17 pfam09799
Predicted membrane protein; This is a 100 amino acid region of a family of proteins conserved ...
 21-127 3.94e-24

Predicted membrane protein; This is a 100 amino acid region of a family of proteins conserved from nematodes to humans. It is predicted to be a transmembrane region but its function is not known.


Pssm-ID: 462907  Cd Length: 107  Bit Score: 89.56  E-value: 3.94e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1859470316  21 MLFYLSGTYYALYFLATLLMITYKSQVFSYPHRYLVLDLALLFLMGILEAVRLYLGTRGNLTEAERPLAASLALTAGTAL 100
Cdd:pfam09799   1 MLLYFNSYYFPLWFLAELLLLIYKGINLPYPGNYLALDVVLLVLLAILEVLRLYLGYKGNLTEKVPPLAAFLLLTLPSQL 80

                          90       100
                  ....*....|....*....|....*..
gi 1859470316 101 LSAHFLLWQALVLWADWALSATLLALH 127
Cdd:pfam09799  81 PLVYLLLLQTYVLRLEYILNAILLALL 107
 
Name Accession Description Interval E-value
Transmemb_17 pfam09799
Predicted membrane protein; This is a 100 amino acid region of a family of proteins conserved ...
 21-127 3.94e-24

Predicted membrane protein; This is a 100 amino acid region of a family of proteins conserved from nematodes to humans. It is predicted to be a transmembrane region but its function is not known.


Pssm-ID: 462907  Cd Length: 107  Bit Score: 89.56  E-value: 3.94e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1859470316  21 MLFYLSGTYYALYFLATLLMITYKSQVFSYPHRYLVLDLALLFLMGILEAVRLYLGTRGNLTEAERPLAASLALTAGTAL 100
Cdd:pfam09799   1 MLLYFNSYYFPLWFLAELLLLIYKGINLPYPGNYLALDVVLLVLLAILEVLRLYLGYKGNLTEKVPPLAAFLLLTLPSQL 80

                          90       100
                  ....*....|....*....|....*..
gi 1859470316 101 LSAHFLLWQALVLWADWALSATLLALH 127
Cdd:pfam09799  81 PLVYLLLLQTYVLRLEYILNAILLALL 107
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH