|
Name |
Accession |
Description |
Interval |
E-value |
| CortBP2 |
pfam09727 |
Cortactin-binding protein-2; This entry is the first approximately 250 residues of ... |
64-246 |
3.86e-64 |
|
Cortactin-binding protein-2; This entry is the first approximately 250 residues of cortactin-binding protein 2. In addition to being a positional candidate for autism this protein is expressed at highest levels in the brain in humans. The human protein has six associated ankyrin repeat domains pfam00023 towards the C-terminus which act as protein-protein interaction domains.
Pssm-ID: 462860 [Multi-domain] Cd Length: 187 Bit Score: 215.16 E-value: 3.86e-64
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 64 DLSRDDLLFLLSILEGELQARDEVIGILRAEKIDLALLEAQYGFVTPKKVLEALQRDAFQAKSAPWQEDIYE----KPMN 139
Cdd:pfam09727 1 DLSKDDLLKLLSILEGELQARDIVIAVLKAEKVKQLLLEARYGFKYPSDPLLALQRDSELLRDQSQDEDVYEamyeKPLA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 140 ELDKVVEKHKESHRRILEQLLMVERSHRQTIMEMEEEKRKHKEYMKKSDEFINLLEQECERLKKLIDQETASQEKKEQEK 219
Cdd:pfam09727 81 ELEKLVEKQRETQRRMLEQLAAAEKRHRRVIRELEEEKRKHARDTAQGDDFTYLLEKERERLKQELEQEKAQQKRLEKEL 160
|
170 180
....*....|....*....|....*..
gi 295424207 220 EKRIKTLKEELTKLKSFALMVVDEQQR 246
Cdd:pfam09727 161 KKLLEKLEEELSKQKQIALLLVKERKR 187
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
185-770 |
7.95e-17 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 85.89 E-value: 7.95e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 185 KKSDEFINLLEQECERLKKLIDQEtasqekkeQEKEKRIKTLKEELTKLKsfalmvvdeqqrltaqlalqrQKIQALTTS 264
Cdd:PRK03918 165 KNLGEVIKEIKRRIERLEKFIKRT--------ENIEELIKEKEKELEEVL---------------------REINEISSE 215
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 265 AKETQGKLALAEARAQEEEQKATRLEkELQTQTTEFHQNQDKIMAKLTNEDSQNRQLRQKLAALS---RQIDELEETNRS 341
Cdd:PRK03918 216 LPELREELEKLEKEVKELEELKEEIE-ELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELEekvKELKELKEKAEE 294
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 342 LRKAEEELQDIKDKINKGEYGNSGIMDEVDELRKRVLDMEGKDEELIKMEEQCRDLNKRLEKetvqSKDFKLEVDKLSVR 421
Cdd:PRK03918 295 YIKLSEFYEEYLDELREIEKRLSRLEEEINGIEERIKELEEKEERLEELKKKLKELEKRLEE----LEERHELYEEAKAK 370
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 422 ITALEKLEDAL-DKSKQECYSLKCNLEKEKmttKQLSEELESLNARIKELEAIESRLEKTEITLKDDLTKLKTLTVMLVD 500
Cdd:PRK03918 371 KEELERLKKRLtGLTPEKLEKELEELEKAK---EEIEEEISKITARIGELKKEIKELKKAIEELKKAKGKCPVCGRELTE 447
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 501 ERK-----TMSEKLKQTEDKLQSTTSQLQAEQNKVTTVtEKLIEETKRALKSKT------DAEEKMYSVTKErddlrnKL 569
Cdd:PRK03918 448 EHRkelleEYTAELKRIEKELKEIEEKERKLRKELREL-EKVLKKESELIKLKElaeqlkELEEKLKKYNLE------EL 520
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 570 KAEEEKGHDLLSKVTILKNRLQSLEaieKDFvkNKLNQDSSKSTAAlhqeNNKIKELSQEVENLKLKLKDMK-AIEDDLM 648
Cdd:PRK03918 521 EKKAEEYEKLKEKLIKLKGEIKSLK---KEL--EKLEELKKKLAEL----EKKLDELEEELAELLKELEELGfESVEELE 591
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 649 KTEDEYETLERRYANERDKAQFLSQELEhaKMELAKYKLAEKtessheqwlFRRLQEEEAKSGHLSREVDALKEKI--HE 726
Cdd:PRK03918 592 ERLKELEPFYNEYLELKDAEKELEREEK--ELKKLEEELDKA---------FEELAETEKRLEELRKELEELEKKYseEE 660
|
570 580 590 600
....*....|....*....|....*....|....*....|....
gi 295424207 727 YMATEDLICHLQGDHSLLQKKLNQQENRNRDLGREIENLTKELE 770
Cdd:PRK03918 661 YEELREEYLELSRELAGLRAELEELEKRREEIKKTLEKLKEELE 704
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
145-729 |
5.66e-16 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 83.19 E-value: 5.66e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 145 VEKHKESHRRILEQLLMVERSHRQTIMEMEEEKRKHKEYMKKSDEFINLLEqECERLKKLIDQETASQEKKEQEKEKRIK 224
Cdd:PRK03918 191 IEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKELEELKEEIE-ELEKELESLEGSKRKLEEKIRELEERIE 269
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 225 TLKEELTKLKSfalmvvdeqqrltaqlalQRQKIQALTTSAKETqgkLALAEARAQEEEQKAtRLEKELQTqttefhqnq 304
Cdd:PRK03918 270 ELKKEIEELEE------------------KVKELKELKEKAEEY---IKLSEFYEEYLDELR-EIEKRLSR--------- 318
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 305 dkimakltnedsqnrqLRQKLAALSRQIDELEETNRSLRKAEEELQDIKDKINKGEYGNS------GIMDEVDELRKRVl 378
Cdd:PRK03918 319 ----------------LEEEINGIEERIKELEEKEERLEELKKKLKELEKRLEELEERHElyeeakAKKEELERLKKRL- 381
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 379 dmegKDEELIKMEEQCRDLNKRLEKETVQSKDFKLEVDKLSVRITALEKLEDALDKSKQECYSLKCNL--EKEKMTTKQL 456
Cdd:PRK03918 382 ----TGLTPEKLEKELEELEKAKEEIEEEISKITARIGELKKEIKELKKAIEELKKAKGKCPVCGRELteEHRKELLEEY 457
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 457 SEELESLNARIKELEAIESRLEKTEITLKDDLTKLKTLTVMlvderKTMSEKLKQTEDKLQS-TTSQLQAEQNKVTTVTE 535
Cdd:PRK03918 458 TAELKRIEKELKEIEEKERKLRKELRELEKVLKKESELIKL-----KELAEQLKELEEKLKKyNLEELEKKAEEYEKLKE 532
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 536 KLIEETKRALKSKTDAEEKMySVTKERDDLRNKLKAEEEKGHDLLSK--------VTILKNRLQSLEAIEKDFVK----- 602
Cdd:PRK03918 533 KLIKLKGEIKSLKKELEKLE-ELKKKLAELEKKLDELEEELAELLKEleelgfesVEELEERLKELEPFYNEYLElkdae 611
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 603 ----------NKLNQDSSKSTAALHQENNKIKELSQEVENLKLKLKdmkaiEDDLMKTEDEYETLERRYANERDKAQFLS 672
Cdd:PRK03918 612 kelereekelKKLEEELDKAFEELAETEKRLEELRKELEELEKKYS-----EEEYEELREEYLELSRELAGLRAELEELE 686
|
570 580 590 600 610
....*....|....*....|....*....|....*....|....*....|....*..
gi 295424207 673 QELEHAKMELAKYKlAEKTEssheqwlFRRLQEEEAKSGHLSREVDALKEKIHEYMA 729
Cdd:PRK03918 687 KRREEIKKTLEKLK-EELEE-------REKAKKELEKLEKALERVEELREKVKKYKA 735
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
288-785 |
7.06e-16 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 82.80 E-value: 7.06e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 288 RLEKELQTQTTEFHQNQDKIMAKLtnedsqnRQLRQKLAALSRQIDELEETNRSLRKAEEELQDIKDKINKGEYGNSGIM 367
Cdd:PRK03918 193 ELIKEKEKELEEVLREINEISSEL-------PELREELEKLEKEVKELEELKEEIEELEKELESLEGSKRKLEEKIRELE 265
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 368 DEVDELRKRVLDMEGKDEELIKME---EQCRDLNKRLEKETVQSKDFKLEVDKLSVRITALEKLEDALDKSKQECYSLK- 443
Cdd:PRK03918 266 ERIEELKKEIEELEEKVKELKELKekaEEYIKLSEFYEEYLDELREIEKRLSRLEEEINGIEERIKELEEKEERLEELKk 345
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 444 --CNLEKEKMTTKQLSEELESLNARIKELEAIESRLEKTEI-TLKDDLTKLKTLTVMLVDERKTMSEK---LKQTEDKLQ 517
Cdd:PRK03918 346 klKELEKRLEELEERHELYEEAKAKKEELERLKKRLTGLTPeKLEKELEELEKAKEEIEEEISKITARigeLKKEIKELK 425
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 518 STTSQLQAEQNKVTTVTEKLIEETKRALKSKTDAE-EKMYSVTKERDDLRNKLKAEEEKGHDLL---SKVTILKNRLQSL 593
Cdd:PRK03918 426 KAIEELKKAKGKCPVCGRELTEEHRKELLEEYTAElKRIEKELKEIEEKERKLRKELRELEKVLkkeSELIKLKELAEQL 505
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 594 EAIEKDFVKNKLnQDSSKSTAALHQENNKIKELSQEVENLKLKLKDMKAIEDDLMKTEDEYETLERRYANERDKAqflsQ 673
Cdd:PRK03918 506 KELEEKLKKYNL-EELEKKAEEYEKLKEKLIKLKGEIKSLKKELEKLEELKKKLAELEKKLDELEEELAELLKEL----E 580
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 674 ELEHAKMELAKYKLAEkTESSHEQWLF-----RRLQEEEAKSGHLSREVDALKEKIHEymaTEDLICHLQGDHSLLQKKL 748
Cdd:PRK03918 581 ELGFESVEELEERLKE-LEPFYNEYLElkdaeKELEREEKELKKLEEELDKAFEELAE---TEKRLEELRKELEELEKKY 656
|
490 500 510
....*....|....*....|....*....|....*..
gi 295424207 749 NQQENRNrdLGREIENLTKELERYRHFSKSLRPSLNE 785
Cdd:PRK03918 657 SEEEYEE--LREEYLELSRELAGLRAELEELEKRREE 691
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
224-773 |
9.78e-16 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 82.68 E-value: 9.78e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 224 KTLKEELTKLKSFALmvVDEQQRLTAQLALQRQKIQALTTSAKETQGKLALAEARAQEEEQKATRLEKELQTQTTEFHQN 303
Cdd:COG1196 216 RELKEELKELEAELL--LLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYEL 293
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 304 QDKIMAKLTNEDSQNRQLRQKLAALSRQIDELEETNRSLRKAEEELQDIKDKINKGEYGNSGIMDEVDELRKRVLDMEGK 383
Cdd:COG1196 294 LAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAE 373
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 384 DEELIKMEEQCRDLNKRLEKETVQSKDFKLEV--------DKLSVRITALEKLEDALDKSKQECYSLKCNLEKEKMTTKQ 455
Cdd:COG1196 374 LAEAEEELEELAEELLEALRAAAELAAQLEELeeaeeallERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAE 453
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 456 LSEELESLNARIKELEAIESRLEKTEITLKDDLTKLKTLTVMLVDERKTMSE--------KLKQTEDKLQSTTSQLQAEQ 527
Cdd:COG1196 454 LEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGflegvkaaLLLAGLRGLAGAVAVLIGVE 533
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 528 NKVTTVTEKLIEETKRALKSKTDAEEKMY-SVTKERDDLR------NKLKAEEEKGHDLLSKVTILKNRLQSLEAIEKDF 600
Cdd:COG1196 534 AAYEAALEAALAAALQNIVVEDDEVAAAAiEYLKAAKAGRatflplDKIRARAALAAALARGAIGAAVDLVASDLREADA 613
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 601 VKNKLNQDSSKSTAALHQENNKIKELSQEVENLKLKLKDMKAIEDDLMKTEDEYETLERRYANERDKAQFLSQELEHAKM 680
Cdd:COG1196 614 RYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEEL 693
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 681 ELAKYKLAEKTESSHEQWLFRRLQEEEAKSGHLSREVDALKEKIHEYMATEDLICHLQG--------DHSLLQKKLNQQE 752
Cdd:COG1196 694 ELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEAleelpeppDLEELERELERLE 773
|
570 580
....*....|....*....|....*
gi 295424207 753 NRNRDLG----REIENLTKELERYR 773
Cdd:COG1196 774 REIEALGpvnlLAIEEYEELEERYD 798
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
176-773 |
3.23e-15 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 80.87 E-value: 3.23e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 176 EKRKHKEYMKKSDEFINLLEQECERLKKLIDQETASQEKKEQekekRIKTLKEELTKLKSFALMVVDEQQRLTAQLALQR 255
Cdd:TIGR02168 233 RLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRL----EVSELEEEIEELQKELYALANEISRLEQQKQILR 308
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 256 QKIQALTTSAKETQGKLALAEARAQEEEQKATRLEK---ELQTQTTEFHQNQDKIMAKLTNEDSQNRQLRQKLAALSRQI 332
Cdd:TIGR02168 309 ERLANLERQLEELEAQLEELESKLDELAEELAELEEkleELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKV 388
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 333 DELEETNRSLRK----AEEELQDIKDKINKGEYGNSGIMDEVDELRKRVLDM--EGKDEELIKMEEQCRDLNKRLEKETV 406
Cdd:TIGR02168 389 AQLELQIASLNNeierLEARLERLEDRRERLQQEIEELLKKLEEAELKELQAelEELEEELEELQEELERLEEALEELRE 468
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 407 QSK-------DFKLEVDKLSVRITALEKLEDALDKSKQECYSLKCNLEKEKMTTKQLSEEL------------------- 460
Cdd:TIGR02168 469 ELEeaeqaldAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLSGILGVLSELIsvdegyeaaieaalggrlq 548
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 461 ----ESLNARIKELEA---------------------IESRLEKTEITLKDDLTKLKTLTVMLVDERKTMSEKLKQTE-- 513
Cdd:TIGR02168 549 avvvENLNAAKKAIAFlkqnelgrvtflpldsikgteIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGVLvv 628
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 514 DKLQSTTSQLQAEQNKVTTVTE--KLIEETKRALKSKTDAEEKMYSVTKERDDLRNKLKAEEEKGHDLLSKVTILKNRLQ 591
Cdd:TIGR02168 629 DDLDNALELAKKLRPGYRIVTLdgDLVRPGGVITGGSAKTNSSILERRREIEELEEKIEELEEKIAELEKALAELRKELE 708
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 592 SLEAIEKDfvknkLNQDSSKSTAALHQENNKIKELSQEVENLklkLKDMKAIEDDLMKTEDEYETLERRYANERDKAQFL 671
Cdd:TIGR02168 709 ELEEELEQ-----LRKELEELSRQISALRKDLARLEAEVEQL---EERIAQLSKELTELEAEIEELEERLEEAEEELAEA 780
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 672 SQELEHAKMELAKYKlaektessheqwlfRRLQEEEAKSGHLSREVDALKEKIHEYMATEDlicHLQGDHSLLQKKLNQQ 751
Cdd:TIGR02168 781 EAEIEELEAQIEQLK--------------EELKALREALDELRAELTLLNEEAANLRERLE---SLERRIAATERRLEDL 843
|
650 660
....*....|....*....|..
gi 295424207 752 ENRNRDLGREIENLTKELERYR 773
Cdd:TIGR02168 844 EEQIEELSEDIESLAAEIEELE 865
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
330-674 |
8.11e-15 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 79.73 E-value: 8.11e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 330 RQIDELEETNRSLRKAEEELQDIKDKINKgeygnsgIMDEVDELRKRVLDMEGKDEELIKMEEQcrdLNKRLEKETVQSK 409
Cdd:TIGR02169 671 SEPAELQRLRERLEGLKRELSSLQSELRR-------IENRLDELSQELSDASRKIGEIEKEIEQ---LEQEEEKLKERLE 740
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 410 DFKLEVDKLSVRITALEKLEDALDKSKQECYSLKCNLEKE--KMTTKQLSEELESLNARIKELEAIESRLEKTEITLKDD 487
Cdd:TIGR02169 741 ELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEAlnDLEARLSHSRIPEIQAELSKLEEEVSRIEARLREIEQK 820
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 488 LTKLKTLTVMLVDERKTMSEKLKQTEDKLQSttsqLQAEQNKVTTVTEKLIEETKRALKSKTDAEEKMYSVTKERDDLRN 567
Cdd:TIGR02169 821 LNRLTLEKEYLEKEIQELQEQRIDLKEQIKS----IEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEA 896
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 568 KLKAEEEKGHDLLSKVTILKNRLQSLEAieKDFVKNKLNQDSSKSTAALHQENNKIKELSQEVENLKLKLKDMKAIEDDL 647
Cdd:TIGR02169 897 QLRELERKIEELEAQIEKKRKRLSELKA--KLEALEEELSEIEDPKGEDEEIPEEELSLEDVQAELQRVEEEIRALEPVN 974
|
330 340
....*....|....*....|....*..
gi 295424207 648 MKTEDEYETLERRYANERDKAQFLSQE 674
Cdd:TIGR02169 975 MLAIQEYEEVLKRLDELKEKRAKLEEE 1001
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
191-771 |
1.03e-14 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 79.33 E-value: 1.03e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 191 INLLEQECERLKKLIDQETASQEKKEQEKEKRIKTLKEELTKLKSFALMVVDEQQRLTAQLALQRQKIQALTTSAKETQG 270
Cdd:TIGR02168 202 LKSLERQAEKAERYKELKAELRELELALLVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEE 281
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 271 KLALAEARAQEEEQKATRLEKELQTQTTEFHQ---NQDKIMAKLTNEDSQNRQLRQKLAALSRQIDELEETNRSLRKAEE 347
Cdd:TIGR02168 282 EIEELQKELYALANEISRLEQQKQILRERLANlerQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELE 361
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 348 ELQDIKDKINKgeyGNSGIMDEVDELRKRVLDMEGK----DEELIKMEEQCRDLNKRLEK-----ETVQSKDFKLEVDKL 418
Cdd:TIGR02168 362 ELEAELEELES---RLEELEEQLETLRSKVAQLELQiaslNNEIERLEARLERLEDRRERlqqeiEELLKKLEEAELKEL 438
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 419 SVRI----TALEKLEDALDKSKQECYSLKCNLEKEKMTTKQLSEELESLNARIKELEAIESRLEKTEITLKDDLTKLKTL 494
Cdd:TIGR02168 439 QAELeeleEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGL 518
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 495 TvmlvDERKTMSEKLKQTEDKLQSTTSQLQAEQNKVTTVTEKLIEETKRALKSKTDAEEKMYSVTKERDDLRNKLKAEEE 574
Cdd:TIGR02168 519 S----GILGVLSELISVDEGYEAAIEAALGGRLQAVVVENLNAAKKAIAFLKQNELGRVTFLPLDSIKGTEIQGNDREIL 594
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 575 KGHDllSKVTILKNRLQSLEAIEK------------DFVKNKLNQ---------------------------DSSKSTAA 615
Cdd:TIGR02168 595 KNIE--GFLGVAKDLVKFDPKLRKalsyllggvlvvDDLDNALELakklrpgyrivtldgdlvrpggvitggSAKTNSSI 672
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 616 LHQENN-------------KIKELSQEVENLKLKLKDMKAIEDDLMKTEDEYET----LERRYANERDKAQFLSQELEHA 678
Cdd:TIGR02168 673 LERRREieeleekieeleeKIAELEKALAELRKELEELEEELEQLRKELEELSRqisaLRKDLARLEAEVEQLEERIAQL 752
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 679 KMELAKYKLAEKTESSHEQWLFRRLQEEEAKSGHLSREVDALKEkihEYMATEDLICHLQGDHSLLQKKLNQQENRNRDL 758
Cdd:TIGR02168 753 SKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKE---ELKALREALDELRAELTLLNEEAANLRERLESL 829
|
650
....*....|...
gi 295424207 759 GREIENLTKELER 771
Cdd:TIGR02168 830 ERRIAATERRLED 842
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
140-726 |
1.12e-14 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 79.41 E-value: 1.12e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 140 ELDKVVEKHKESHRRILEQLLMVERSHRQTIMEMEEEKRKHKEYMKKSDEfinllEQECERLKKLIDQETASQEKKEQEK 219
Cdd:PTZ00121 1198 DARKAEAARKAEEERKAEEARKAEDAKKAEAVKKAEEAKKDAEEAKKAEE-----ERNNEEIRKFEEARMAHFARRQAAI 1272
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 220 EKRIKTLKEELTKL----KSFALMVVDEQQRL--TAQLALQRQKIQALTTSAKETQGKLALAEARAQEEEQKATRLEKEL 293
Cdd:PTZ00121 1273 KAEEARKADELKKAeekkKADEAKKAEEKKKAdeAKKKAEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEA 1352
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 294 QTQTTEFHQNQDKIMA--KLTNEDSQNRQLRQKLAALSRQIDELEETNRSLRKAEEELQDIKDKINKGEYGNSGIMD--E 369
Cdd:PTZ00121 1353 EAAADEAEAAEEKAEAaeKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEkkK 1432
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 370 VDELRKRVLDMEGKDEELIKMEEqcrdlnKRLEKETVQSKDFKLEVDKLSVRITALEKLEDAldKSKQECYSLKCNLEKE 449
Cdd:PTZ00121 1433 ADEAKKKAEEAKKADEAKKKAEE------AKKAEEAKKKAEEAKKADEAKKKAEEAKKADEA--KKKAEEAKKKADEAKK 1504
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 450 KMTTKQLSEELESLNARIKELEAIESRLEKTEITLKDDLTKLKTLTVMLVDERKTMSEKLKQTEDKLQSTTSQLQAEQNK 529
Cdd:PTZ00121 1505 AAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAE 1584
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 530 VTtvteKLIEETKRALKSKTDAEEKMYSVTKERDDLRNKLKAEEekghdlLSKVTILKNRLQSLEAIEKDFVKN--KLNQ 607
Cdd:PTZ00121 1585 EA----KKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEE------LKKAEEEKKKVEQLKKKEAEEKKKaeELKK 1654
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 608 DSSKSTAALHQENNKIKELSQEVENLKLKLKDMKAIEDDLMKTEDE---YETLERRYANERDKAQFLSQELE--HAKMEL 682
Cdd:PTZ00121 1655 AEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEakkAEELKKKEAEEKKKAEELKKAEEenKIKAEE 1734
|
570 580 590 600
....*....|....*....|....*....|....*....|....
gi 295424207 683 AKYKLAEKTESSHEqwlFRRLQEEEAKSGHLSREVDALKEKIHE 726
Cdd:PTZ00121 1735 AKKEAEEDKKKAEE---AKKDEEEKKKIAHLKKEEEKKAEEIRK 1775
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
164-785 |
1.12e-14 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 79.34 E-value: 1.12e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 164 RSHRQTIMEMEEEKRKHKEYMKKSDEFINLLEQECERLKKLIDQETASQEKKEQEKEKRIKTLKEELTKLKSFALMVVDE 243
Cdd:TIGR02169 233 EALERQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEEQLRVKEKIGELEAEIASLERSIAE 312
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 244 QQRLTAQLALQRQKIQALTTSAKEtqgklalaEARAQEEEQKATRLEKE-LQTQTTEFHQNQDKIMAKLTNEDSQNRQLR 322
Cdd:TIGR02169 313 KERELEDAEERLAKLEAEIDKLLA--------EIEELEREIEEERKRRDkLTEEYAELKEELEDLRAELEEVDKEFAETR 384
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 323 QKLAALSRQID----ELEETNRSLRKAEEELQDIKDKINKGEYGNSGIMDEVDELRKRvldMEGKDEELIKMEEQCRDLN 398
Cdd:TIGR02169 385 DELKDYREKLEklkrEINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEE---KEDKALEIKKQEWKLEQLA 461
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 399 KRLEKETVQSKDFKLEVDKLSVRITALEKLEDALDKSKQecySLKCNLEKEKMTTKQLSEELESLNARIKEL-------- 470
Cdd:TIGR02169 462 ADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQAR---ASEERVRGGRAVEEVLKASIQGVHGTVAQLgsvgerya 538
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 471 EAIES----RLEKteITLKDDLT-----------KLKTLTVMLVDERKTMSEKLK---------------QTEDKLQS-- 518
Cdd:TIGR02169 539 TAIEVaagnRLNN--VVVEDDAVakeaiellkrrKAGRATFLPLNKMRDERRDLSilsedgvigfavdlvEFDPKYEPaf 616
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 519 --------------TTSQLQAEQNKVT---------------TVTEKLIEETKRALKSKT-DAEEKMYSVTKERDDLRNK 568
Cdd:TIGR02169 617 kyvfgdtlvvedieAARRLMGKYRMVTlegelfeksgamtggSRAPRGGILFSRSEPAELqRLRERLEGLKRELSSLQSE 696
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 569 LKAEEEKGHDLLSKVTILKnrlQSLEAIEKDfvKNKLNQDSSKSTAALHQENNKIKELSQEVENLKLKLKDMKA----IE 644
Cdd:TIGR02169 697 LRRIENRLDELSQELSDAS---RKIGEIEKE--IEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEArieeLE 771
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 645 DDLMKTEDEYETLERRYANERDK---AQFLSQELEHAKMELAKYKLAEKTESSHEqwlfrRLQEEEAKSGHLSREVDALK 721
Cdd:TIGR02169 772 EDLHKLEEALNDLEARLSHSRIPeiqAELSKLEEEVSRIEARLREIEQKLNRLTL-----EKEYLEKEIQELQEQRIDLK 846
|
650 660 670 680 690 700
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 295424207 722 EKIHEYMATEDLichLQGDHSLLQKKLNQQENRNRDLGREIENLTKELERYRHFSKSLRPSLNE 785
Cdd:TIGR02169 847 EQIKSIEKEIEN---LNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEE 907
|
|
| PRK02224 |
PRK02224 |
DNA double-strand break repair Rad50 ATPase; |
140-596 |
4.97e-14 |
|
DNA double-strand break repair Rad50 ATPase;
Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 77.00 E-value: 4.97e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 140 ELDKVVEKHKEShRRILEQLLMVERSHRQTIMEMEEEKRKHKEYMKKSDEFINLLEQECERLKKLIDQETASQEkkeqek 219
Cdd:PRK02224 238 EADEVLEEHEER-REELETLEAEIEDLRETIAETEREREELAEEVRDLRERLEELEEERDDLLAEAGLDDADAE------ 310
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 220 ekRIKTLKEELTklksfalmvvDEQQRLTAQLALQRQKIQALTTSAKETQGKLALAEARAQEEEQKATRLEKELQTQTTE 299
Cdd:PRK02224 311 --AVEARREELE----------DRDEELRDRLEECRVAAQAHNEEAESLREDADDLEERAEELREEAAELESELEEAREA 378
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 300 FHQNQDKIMA-----------------KLTNEDSQNRQLRQKLAALSRQIDELEETNRSLRKAEEELQDIKDKINKGEYG 362
Cdd:PRK02224 379 VEDRREEIEEleeeieelrerfgdapvDLGNAEDFLEELREERDELREREAELEATLRTARERVEEAEALLEAGKCPECG 458
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 363 ----NSGIMDEVDELRKRVLDMEgkdEELIKMEEQCRDLNKRLE--KETVQSKDfklEVDKLSVRITALEKL----EDAL 432
Cdd:PRK02224 459 qpveGSPHVETIEEDRERVEELE---AELEDLEEEVEEVEERLEraEDLVEAED---RIERLEERREDLEELiaerRETI 532
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 433 DKSKQECYSLK---------------------CNLEKEKMTTKQLSEELESLNARIKELEAIESRLEKTEiTLKDDLTKL 491
Cdd:PRK02224 533 EEKRERAEELReraaeleaeaeekreaaaeaeEEAEEAREEVAELNSKLAELKERIESLERIRTLLAAIA-DAEDEIERL 611
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 492 KtltvmlvDERKTMSEKLKQTEDKLQST---TSQLQAEQNKvtTVTEKLIEETKRALKSKTDAEEKMYSVTKERDDLRNK 568
Cdd:PRK02224 612 R-------EKREALAELNDERRERLAEKrerKRELEAEFDE--ARIEEAREDKERAEEYLEQVEEKLDELREERDDLQAE 682
|
490 500 510
....*....|....*....|....*....|.
gi 295424207 569 ---LKAEEEKGHDLLSKVTILKNRLQSLEAI 596
Cdd:PRK02224 683 igaVENELEELEELRERREALENRVEALEAL 713
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
170-526 |
6.54e-14 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 76.65 E-value: 6.54e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 170 IMEMEEEKRKHKEYM----KKSDEFINLLEQECERLKKL-IDQETAsqekkeqekeKRIKTLKEELTKLKSFALMvvdeq 244
Cdd:TIGR02169 165 VAEFDRKKEKALEELeeveENIERLDLIIDEKRQQLERLrREREKA----------ERYQALLKEKREYEGYELL----- 229
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 245 qrltaqlalqrQKIQALTTSAKETQGKLALAEARAQEEEQKATRLEKELQTQTTEFHQNQDKIMAKLTNEdsqNRQLRQK 324
Cdd:TIGR02169 230 -----------KEKEALERQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEE---QLRVKEK 295
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 325 LAALSRQI----DELEETNRSLRKAEEELQDIKDKINKGEYGNSGIMDEVDELRKRVLDMEgkdEELIKMEEQCRDLNKR 400
Cdd:TIGR02169 296 IGELEAEIasleRSIAEKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLT---EEYAELKEELEDLRAE 372
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 401 LEKEtvqSKDFKLEVDKLSVRITALEKLedaldksKQECYSLKCNLEKEKMTTKQLSEELESLNARIKELEA----IESR 476
Cdd:TIGR02169 373 LEEV---DKEFAETRDELKDYREKLEKL-------KREINELKRELDRLQEELQRLSEELADLNAAIAGIEAkineLEEE 442
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|
gi 295424207 477 LEKTEITLKDDLTKLKTLTVMLVDERKTMsEKLKQTEDKLQSTTSQLQAE 526
Cdd:TIGR02169 443 KEDKALEIKKQEWKLEQLAADLSKYEQEL-YDLKEEYDRVEKELSKLQRE 491
|
|
| CCDC158 |
pfam15921 |
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ... |
222-769 |
1.60e-13 |
|
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.
Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 75.54 E-value: 1.60e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 222 RIKTLKEELTKLKSfalmvvDEQQRLTAQLALQRQKIQALTTsakETQGKLALAEARAQEEEQKATRLEKELQTQTTEFH 301
Cdd:pfam15921 239 RIFPVEDQLEALKS------ESQNKIELLLQQHQDRIEQLIS---EHEVEITGLTEKASSARSQANSIQSQLEIIQEQAR 309
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 302 QNQDKIMAKLTNEDSQNRQLRQKLAALSRQI-DELEETNRSLRKAEEELQDIKDKINKGEYgNSGIMDevDELRKRVLDM 380
Cdd:pfam15921 310 NQNSMYMRQLSDLESTVSQLRSELREAKRMYeDKIEELEKQLVLANSELTEARTERDQFSQ-ESGNLD--DQLQKLLADL 386
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 381 EGKDEELIKMEEQCRDLNKRLEKETVQSKDFKLEVDKLSVRITALEKLEDALdksKQECYSL-----------KCNLEKE 449
Cdd:pfam15921 387 HKREKELSLEKEQNKRLWDRDTGNSITIDHLRRELDDRNMEVQRLEALLKAM---KSECQGQmerqmaaiqgkNESLEKV 463
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 450 KMTTKQLSEELESLNARIKELEAIESRLEKTEITLKD-----------------DLTKLKTltvmLVDERKTMSEKLKQT 512
Cdd:pfam15921 464 SSLTAQLESTKEMLRKVVEELTAKKMTLESSERTVSDltaslqekeraieatnaEITKLRS----RVDLKLQELQHLKNE 539
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 513 EDKLQSTTSQLQA------EQNKVTTVTEKLIEETKRALKSKTDAEEKMY----SVTKERDDLRNKLKAEEEKGHDLLSK 582
Cdd:pfam15921 540 GDHLRNVQTECEAlklqmaEKDKVIEILRQQIENMTQLVGQHGRTAGAMQvekaQLEKEINDRRLELQEFKILKDKKDAK 619
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 583 VTILKNRLQSLEaiekdFVKNKLNQDSSKSTAAlhqennkIKELSQEVENLklkLKDMKAIEDDLMKTEDEYETLERRYA 662
Cdd:pfam15921 620 IRELEARVSDLE-----LEKVKLVNAGSERLRA-------VKDIKQERDQL---LNEVKTSRNELNSLSEDYEVLKRNFR 684
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 663 NErdkaqflSQELEhakMELAKYKLAEKTESSHEQWLFRRLQEEEAKSGHLSREVDALKEKIheyMATEDLICHLQGDHS 742
Cdd:pfam15921 685 NK-------SEEME---TTTNKLKMQLKSAQSELEQTRNTLKSMEGSDGHAMKVAMGMQKQI---TAKRGQIDALQSKIQ 751
|
570 580
....*....|....*....|....*..
gi 295424207 743 LLQKKLNQQENRNRDLGREIENLTKEL 769
Cdd:pfam15921 752 FLEEAMTNANKEKHFLKEEKNKLSQEL 778
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
231-578 |
2.30e-13 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 75.10 E-value: 2.30e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 231 TKLKSFALMVVDEQQRLTAQLALQRQKIQALTTSAKETQGKLALAEARAQEEEQKATRLEKELQTQTTEFHQNQDKIMA- 309
Cdd:TIGR02169 670 RSEPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSl 749
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 310 --KLTNEdsqnrqlRQKLAALSRQIDELEETnrsLRKAEEELQDIKDKINKGEYGNsgIMDEVDELRKRVLDMEGKDEEl 387
Cdd:TIGR02169 750 eqEIENV-------KSELKELEARIEELEED---LHKLEEALNDLEARLSHSRIPE--IQAELSKLEEEVSRIEARLRE- 816
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 388 IKMEEQCRDLNKRLEKETVQSKdfKLEVDKLSVRITALEKLEDALDKSKQEcysLKCNLEKEKMTTKQLSEELESLNARI 467
Cdd:TIGR02169 817 IEQKLNRLTLEKEYLEKEIQEL--QEQRIDLKEQIKSIEKEIENLNGKKEE---LEEELEELEAALRDLESRLGDLKKER 891
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 468 KELEAIESRLEKTEITLKDDLTKLKTLTVMLVDERKTMSEKLKQTED----------------KLQSTTSQLQAEQNKVT 531
Cdd:TIGR02169 892 DELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDpkgedeeipeeelsleDVQAELQRVEEEIRALE 971
|
330 340 350 360
....*....|....*....|....*....|....*....|....*..
gi 295424207 532 TVTEKLIEETKRALKSKTDAEEKMYSVTKERDDLRNKLKAEEEKGHD 578
Cdd:TIGR02169 972 PVNMLAIQEYEEVLKRLDELKEKRAKLEEERKAILERIEEYEKKKRE 1018
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
167-797 |
3.60e-13 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 74.41 E-value: 3.60e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 167 RQTIMEMEEEKRKHKEYMKKSDEFINLLE-QECERLKKLIDQETASQEKKEQEKEKRIKTLKEELTKLKSFALMVVDEQQ 245
Cdd:PTZ00121 1104 KKTETGKAEEARKAEEAKKKAEDARKAEEaRKAEDARKAEEARKAEDAKRVEIARKAEDARKAEEARKAEDAKKAEAARK 1183
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 246 RLTAQLALQRQKIQAL--TTSAKETQGKLALAEARAQEEEQKATRLEKELQTQttefhqnQDKIMAKLTNEDSQNRQLRQ 323
Cdd:PTZ00121 1184 AEEVRKAEELRKAEDArkAEAARKAEEERKAEEARKAEDAKKAEAVKKAEEAK-------KDAEEAKKAEEERNNEEIRK 1256
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 324 KLAALSRQIDELEETNRS--LRKAeEELQDIKDKINKGEYGNSGIMDEVDELRKRVLDMEGKDEELIKMEE---QCRDLN 398
Cdd:PTZ00121 1257 FEEARMAHFARRQAAIKAeeARKA-DELKKAEEKKKADEAKKAEEKKKADEAKKKAEEAKKADEAKKKAEEakkKADAAK 1335
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 399 KRLEKETVQSKDFKLEVDKLSVRITALEKLEDAlDKSKQECYSLKCNLEKEKMTTKQLSEEL----ESLNARIKELEAIE 474
Cdd:PTZ00121 1336 KKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEA-AEKKKEEAKKKADAAKKKAEEKKKADEAkkkaEEDKKKADELKKAA 1414
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 475 SRLEKTEITLKDDLTKLKTLTVMLVDERKTMSEKL-KQTEDKLQSTTSQLQAEQNKVTTVTEKLIEETKRALKSKTDAEE 553
Cdd:PTZ00121 1415 AAKKKADEAKKKAEEKKKADEAKKKAEEAKKADEAkKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEE 1494
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 554 KMYSVTKERDDLRNKLKAEEEKGHDLLSKVTILKNRLQSLEAIEKDFVKNKLNQDSSKSTAALH--QENNKIKELSQEVE 631
Cdd:PTZ00121 1495 AKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADELKKAEELKkaEEKKKAEEAKKAEE 1574
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 632 NLKLKLK---DMKAIE----DDLMKTEDEYETLE----RRYANERDKAQFLSQElEHAKMELAKYKLAEKTESSHEQWLF 700
Cdd:PTZ00121 1575 DKNMALRkaeEAKKAEeariEEVMKLYEEEKKMKaeeaKKAEEAKIKAEELKKA-EEEKKKVEQLKKKEAEEKKKAEELK 1653
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 701 RRLQEEEAKSGHLSREVDALKEKIHEYMATEDlichlqgdhslLQKKLNQQENRNRDLGREIENLTKELERYRHFSKSLR 780
Cdd:PTZ00121 1654 KAEEENKIKAAEEAKKAEEDKKKAEEAKKAEE-----------DEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELK 1722
|
650
....*....|....*..
gi 295424207 781 PSLNERRISDPQVFSKE 797
Cdd:PTZ00121 1723 KAEEENKIKAEEAKKEA 1739
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
304-770 |
4.29e-13 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 73.94 E-value: 4.29e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 304 QDKIMAKLTNEDSQNRQLRQKLaalsrQIDELEetnrslrKAEEELQDIKDKINKgeygnsgimdEVDELRKRVLDMEGK 383
Cdd:PRK03918 134 QGEIDAILESDESREKVVRQIL-----GLDDYE-------NAYKNLGEVIKEIKR----------RIERLEKFIKRTENI 191
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 384 DEELIKMEEQCRDLNKRLEKETVQSKDFKLEVDKLSVRITALEKLEDALDKSKQECYSLKCNLEKEKMTTKQLSEELESL 463
Cdd:PRK03918 192 EELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKELEELKEEIEELEKELESLEGSKRKLEEKIRELEERIEEL 271
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 464 NARIKELEAIESRLEKTEitlkddltklktltvMLVDERKTMSEKLKQTEDKLQsttsqlqaEQNKVTTVTEKLIEETKR 543
Cdd:PRK03918 272 KKEIEELEEKVKELKELK---------------EKAEEYIKLSEFYEEYLDELR--------EIEKRLSRLEEEINGIEE 328
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 544 ALKSKTDAEEKMYSVTKERDDLRNKLkAEEEKGHDLLSKVTILKNRLQSLEAIEKDFVKNKLNQDSSKSTAALHQENNKI 623
Cdd:PRK03918 329 RIKELEEKEERLEELKKKLKELEKRL-EELEERHELYEEAKAKKEELERLKKRLTGLTPEKLEKELEELEKAKEEIEEEI 407
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 624 KELSQEVENLKLKLKDMKAIEDDLMK------------TEDEYETLERRYANERDKAQFLSQELEHAKMELAKYKLAEKT 691
Cdd:PRK03918 408 SKITARIGELKKEIKELKKAIEELKKakgkcpvcgrelTEEHRKELLEEYTAELKRIEKELKEIEEKERKLRKELRELEK 487
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 692 ESSHEQWLFRRL----QEEEAKSGHLSREVDALKEKIHEYMATEDLICHLQGDHSLLQ---KKLNQQENRNRDLGREIEN 764
Cdd:PRK03918 488 VLKKESELIKLKelaeQLKELEEKLKKYNLEELEKKAEEYEKLKEKLIKLKGEIKSLKkelEKLEELKKKLAELEKKLDE 567
|
....*.
gi 295424207 765 LTKELE 770
Cdd:PRK03918 568 LEEELA 573
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
112-707 |
5.64e-13 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 74.02 E-value: 5.64e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 112 KVLEALQRDAFQAKSA------PWQEDIYEKPMNELDKVVEKHKESHRRILEQLLMVERSHRQTIMEMEEEKRKHKEYMK 185
Cdd:PTZ00121 1230 KKAEEAKKDAEEAKKAeeernnEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEKKKADEAKK 1309
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 186 KSDEfinllEQECERLKKLIDQ-----ETASQEKKEQEKEKRIKTLKEELTKLKSFALMVVDEQQRLTAQLAlqRQKIQA 260
Cdd:PTZ00121 1310 KAEE-----AKKADEAKKKAEEakkkaDAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEA--KKKADA 1382
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 261 LTTSAKETQgKLALAEARAQEEEQKATRLEKElqtqttEFHQNQDKIMAKLTNEDSQNRQLRQKlAALSRQIDELEETNR 340
Cdd:PTZ00121 1383 AKKKAEEKK-KADEAKKKAEEDKKKADELKKA------AAAKKKADEAKKKAEEKKKADEAKKK-AEEAKKADEAKKKAE 1454
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 341 SLRKAEEELQDIKDKINKGEYGNSG-IMDEVDELRKRVLDMEGKDEELIKMEEQCR--DLNKRLEKETVQSKDFKLEVDK 417
Cdd:PTZ00121 1455 EAKKAEEAKKKAEEAKKADEAKKKAeEAKKADEAKKKAEEAKKKADEAKKAAEAKKkaDEAKKAEEAKKADEAKKAEEAK 1534
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 418 LSVRITALEKLEDALDKSKQEcySLKCNLEKEKMTTKQLSEELESLNAR-IKELEAIESRLEKTEITLKDDLTKLKTLTV 496
Cdd:PTZ00121 1535 KADEAKKAEEKKKADELKKAE--ELKKAEEKKKAEEAKKAEEDKNMALRkAEEAKKAEEARIEEVMKLYEEEKKMKAEEA 1612
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 497 MLVDERKTMSEKLKQTEDklqsttsqlqaEQNKVTTVTEKLIEETKRALKSKTDAEE-KMYSVTKERDDLRNKLKAEEEK 575
Cdd:PTZ00121 1613 KKAEEAKIKAEELKKAEE-----------EKKKVEQLKKKEAEEKKKAEELKKAEEEnKIKAAEEAKKAEEDKKKAEEAK 1681
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 576 GHDllskvtilKNRLQSLEAIEKDFVKNKLNQDSSKSTAalhQENNKIKELSQEVENLKLKLKDMKAIEDDLMKTEDEYE 655
Cdd:PTZ00121 1682 KAE--------EDEKKAAEALKKEAEEAKKAEELKKKEA---EEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAEEAK 1750
|
570 580 590 600 610
....*....|....*....|....*....|....*....|....*....|..
gi 295424207 656 TLErryaNERDKAQFLSQELEHAKMELAKYKLAEKTESSHEQWLFRRLQEEE 707
Cdd:PTZ00121 1751 KDE----EEKKKIAHLKKEEEKKAEEIRKEKEAVIEEELDEEDEKRRMEVDK 1798
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
139-773 |
6.49e-13 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 73.55 E-value: 6.49e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 139 NELDKVVEKHKESHRRILEQLLMVERShrqtIMEMEEEKRKHKEYMKKSDEFINLLEQECERLKKLIDQETAsqekKEQE 218
Cdd:TIGR02168 298 SRLEQQKQILRERLANLERQLEELEAQ----LEELESKLDELAEELAELEEKLEELKEELESLEAELEELEA----ELEE 369
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 219 KEKRIKTLKEELTKLKSFALMVVDEQQRLTAQLALQRQKIQALTTSAKETQGKLALAEARAQEEEQKATRLE-------- 290
Cdd:TIGR02168 370 LESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQAEleeleeel 449
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 291 KELQTQTTEFHQNQDKIMAKLTNEDSQNRQLRQKLAALSRQIDELEETNRSLRKAEEELQDIKDKINKGeygnSGIMD-- 368
Cdd:TIGR02168 450 EELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGL----SGILGvl 525
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 369 ----EVDE---------LRKRVLDMEGKDEELIkMEEQCRDLNKRLEKETVqskdfkLEVDklSVRITALEKLEDALDKS 435
Cdd:TIGR02168 526 seliSVDEgyeaaieaaLGGRLQAVVVENLNAA-KKAIAFLKQNELGRVTF------LPLD--SIKGTEIQGNDREILKN 596
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 436 KQECYSLKCNLEKekmTTKQLSEELESLNARIKELEAIESRLEK--------TEITLKDDL-------TKLKTLTVMLVD 500
Cdd:TIGR02168 597 IEGFLGVAKDLVK---FDPKLRKALSYLLGGVLVVDDLDNALELakklrpgyRIVTLDGDLvrpggviTGGSAKTNSSIL 673
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 501 ERKTMSEKLKQTEDKLQSTTSQLQAEQNKVTTVTEKLIEETKRALKSKTDAEekmysvtKERDDLRNKLKAEEEKGHDLL 580
Cdd:TIGR02168 674 ERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELS-------RQISALRKDLARLEAEVEQLE 746
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 581 SKVTILKNRLQSLEAIEkdfvkNKLNQDSSKSTAALHQENNKIKELSQEVENLKlklKDMKAIEDDLMKTEDEYETLERR 660
Cdd:TIGR02168 747 ERIAQLSKELTELEAEI-----EELEERLEEAEEELAEAEAEIEELEAQIEQLK---EELKALREALDELRAELTLLNEE 818
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 661 YANERDKAQFLSQELEHAKMELAKYKLAEKTESSHEQWLFRRLQEEEAKSGHLSREVDALKEkihEYMATEDLICHLQGD 740
Cdd:TIGR02168 819 AANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLN---ERASLEEALALLRSE 895
|
650 660 670
....*....|....*....|....*....|...
gi 295424207 741 HSLLQKKLNQQENRNRDLGREIENLTKELERYR 773
Cdd:TIGR02168 896 LEELSEELRELESKRSELRRELEELREKLAQLE 928
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
252-575 |
8.84e-12 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 69.70 E-value: 8.84e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 252 ALQRQKIQALTTSAKETQGKLALAEARAQEEEQKATRLEKELQTQTTEFHQNQDKIMAKLTnedsQNRQLRQKLAALSRQ 331
Cdd:TIGR02168 666 AKTNSSILERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSR----QISALRKDLARLEAE 741
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 332 IDELEETNRSLRKAEEELQDIKDKINKGEYGNSGIMDEVDELRKRVldmegkDEELIKMEEQCRDLNKRLEKETVQSKDF 411
Cdd:TIGR02168 742 VEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEEL------EAQIEQLKEELKALREALDELRAELTLL 815
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 412 KLEVDKLSVRITALEKLEDALDKSKQEcyslkcnLEKEKmttKQLSEELESLNARIKELEAIESRLEKTEITLKDDLTKL 491
Cdd:TIGR02168 816 NEEAANLRERLESLERRIAATERRLED-------LEEQI---EELSEDIESLAAEIEELEELIEELESELEALLNERASL 885
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 492 KTLTVMLVDERKTMSEKLKQTEDKLQSTTSQLQAEQNKVTTVTEKL------IEETKRALKSK-----TDAEEKMYSVTK 560
Cdd:TIGR02168 886 EEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLeglevrIDNLQERLSEEysltlEEAEALENKIED 965
|
330
....*....|....*
gi 295424207 561 ERDDLRNKLKAEEEK 575
Cdd:TIGR02168 966 DEEEARRRLKRLENK 980
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
139-517 |
1.98e-11 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 68.54 E-value: 1.98e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 139 NELDKVVEKHKESHRRI--LEQLLMVERSHRQTIMEMEEEKRKHKEYMKKSdefINLLEQECERLKKLIDQETAsqekke 216
Cdd:TIGR02168 677 REIEELEEKIEELEEKIaeLEKALAELRKELEELEEELEQLRKELEELSRQ---ISALRKDLARLEAEVEQLEE------ 747
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 217 qekekRIKTLKEELTKLKSFALMVVDEQQRLTAQLALQRQKIQALTTSAKETQGKLALAEARAQEEEQKATRLEKELQTQ 296
Cdd:TIGR02168 748 -----RIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANL 822
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 297 TTEFHQNQDKIMAKLTNEDSQNRQLRQKLAALSRQIDELEETNRSLRKAEEELQDIKDKINKGEYGNSGIMDEVDELRKR 376
Cdd:TIGR02168 823 RERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEE 902
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 377 VLDMEGKDEELikmEEQCRDLNKRLEKETVQSKDFKLEVDKLSVRITALEKLEDALDKSKQECYSLKCNLEKEKMttKQL 456
Cdd:TIGR02168 903 LRELESKRSEL---RRELEELREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLEEAEALENKIEDDEEEARRRL--KRL 977
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 295424207 457 SEELESLN----ARIKELEAIESRLEKTEiTLKDDLTK-LKTLTVMLVDERKTMSEKLKQTEDKLQ 517
Cdd:TIGR02168 978 ENKIKELGpvnlAAIEEYEELKERYDFLT-AQKEDLTEaKETLEEAIEEIDREARERFKDTFDQVN 1042
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
257-562 |
3.89e-11 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 67.79 E-value: 3.89e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 257 KIQALTTSAKETQGKLALAEARAQEEEQKAtrLEKELQTQTTEFHQNQDKImakltnedsqnRQLRQKLAALSRQIDELE 336
Cdd:TIGR02169 212 RYQALLKEKREYEGYELLKEKEALERQKEA--IERQLASLEEELEKLTEEI-----------SELEKRLEEIEQLLEELN 278
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 337 EtnRSLRKAEEELQDIKDKINKGEYGNSGIMDEVDELRKRVLDMEGK----DEELIKMEEQCRDLNKRLEKEtvqskdfK 412
Cdd:TIGR02169 279 K--KIKDLGEEEQLRVKEKIGELEAEIASLERSIAEKERELEDAEERlaklEAEIDKLLAEIEELEREIEEE-------R 349
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 413 LEVDKLsvrITALEKLEDALDKSKQECYSLKCNLEKEKMTTKQLSEELESLNARIKELEAIESRL--EKTEIT-----LK 485
Cdd:TIGR02169 350 KRRDKL---TEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREINELKRELDRLqeELQRLSeeladLN 426
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 295424207 486 DDLTKLKTLTVMLVDERKTMSEKLKQTEDKLQSTTSQLQAEQNKVTTVTEKL--IEETKRALKSKTDAEEKMYSVTKER 562
Cdd:TIGR02169 427 AAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYdrVEKELSKLQRELAEAEAQARASEER 505
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
130-650 |
4.64e-11 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 66.97 E-value: 4.64e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 130 QEDIYEKPMNELDKVVEKHKeSHRRILEQLLMVershrqtimeMEEEKRKHKEYMKKsdefINLLEQECERLKKLIDQET 209
Cdd:TIGR04523 174 ELNLLEKEKLNIQKNIDKIK-NKLLKLELLLSN----------LKKKIQKNKSLESQ----ISELKKQNNQLKDNIEKKQ 238
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 210 ASQEKKEQEkekrIKTLKEELTKLKSFALMVVDEQQRLTAQLALQRQKIQALTTSAKETQGKLAlaearaQEEEQKATRL 289
Cdd:TIGR04523 239 QEINEKTTE----ISNTQTQLNQLKDEQNKIKKQLSEKQKELEQNNKKIKELEKQLNQLKSEIS------DLNNQKEQDW 308
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 290 EKELQTQTTEFHQNQDKIMAKLTNEDSQNRQLRQKLAALSRQIDELEETNRSLRkaeEELQDIKDKINKGEYGNSGIMDE 369
Cdd:TIGR04523 309 NKELKSELKNQEKKLEEIQNQISQNNKIISQLNEQISQLKKELTNSESENSEKQ---RELEEKQNEIEKLKKENQSYKQE 385
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 370 VDELRKRVLDMEGK-----------DEELIKMEEQCRDLNKRLEKETVQSKDFKLEVDKLSVRITALEKLEDALDKS--- 435
Cdd:TIGR04523 386 IKNLESQINDLESKiqnqeklnqqkDEQIKKLQQEKELLEKEIERLKETIIKNNSEIKDLTNQDSVKELIIKNLDNTres 465
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 436 -KQECYSLKCNLEKEKMTTKQLSEELESLNARIKELEAIESRLEKTEITLKDDLTKLKTLTVMLVDERKTMSEKLKQTED 514
Cdd:TIGR04523 466 lETQLKVLSRSINKIKQNLEQKQKELKSKEKELKKLNEEKKELEEKVKDLTKKISSLKEKIEKLESEKKEKESKISDLED 545
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 515 KLQS-----TTSQLQAEQNKVTTVTEKLIEETKRALKSKTDAEEKMYSVTKERDDLRNKLKAEEEKGHDLLSKVTILKNR 589
Cdd:TIGR04523 546 ELNKddfelKKENLEKEIDEKNKEIEELKQTQKSLKKKQEEKQELIDQKEKEKKDLIKEIEEKEKKISSLEKELEKAKKE 625
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 295424207 590 LQSLEAIEK--DFVKNKLNQDsskstaaLHQENNKIKELSQEVENLKLKLKDMKAIEDDLMKT 650
Cdd:TIGR04523 626 NEKLSSIIKniKSKKNKLKQE-------VKQIKETIKEIRNKWPEIIKKIKESKTKIDDIIEL 681
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
135-783 |
5.27e-11 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 67.40 E-value: 5.27e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 135 EKPMNELDKVVEKHKESH---RRILEQL--LMVERSHRQTIMEMEEEKRKHKEYM-----KKSDEFINLLEQECERLKKL 204
Cdd:TIGR02169 173 EKALEELEEVEENIERLDliiDEKRQQLerLRREREKAERYQALLKEKREYEGYEllkekEALERQKEAIERQLASLEEE 252
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 205 IDQETASQEKKEQEKEKRIKTLKEELTKLKSF----ALMVVDEQQRLTAQLALQRQKIQALTTSAKETQGKLALAEARAQ 280
Cdd:TIGR02169 253 LEKLTEEISELEKRLEEIEQLLEELNKKIKDLgeeeQLRVKEKIGELEAEIASLERSIAEKERELEDAEERLAKLEAEID 332
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 281 EEEQKATRLEKELQTQ-------TTEFHQNQDKIM---AKLTNEDSQNRQLRQKLAALSRQID----ELEETNRSLRKAE 346
Cdd:TIGR02169 333 KLLAEIEELEREIEEErkrrdklTEEYAELKEELEdlrAELEEVDKEFAETRDELKDYREKLEklkrEINELKRELDRLQ 412
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 347 EELQDIKDKINKGEYGNSGIMDEVDELRKRVLDmegKDEELIKMEEQCRDLNKRLEKETVQSKDFKLEVDKLSVRITALE 426
Cdd:TIGR02169 413 EELQRLSEELADLNAAIAGIEAKINELEEEKED---KALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQ 489
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 427 KLEDALDKSKQecySLKCNLEKEKMTTKQLSEELESLNARIKEL--------EAIES----RLEKteITLKDDLT----- 489
Cdd:TIGR02169 490 RELAEAEAQAR---ASEERVRGGRAVEEVLKASIQGVHGTVAQLgsvgeryaTAIEVaagnRLNN--VVVEDDAVakeai 564
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 490 ------KLKTLTVMLVDERKTMSEKLK---------------QTEDKLQS----------------TTSQLQAEQNKVT- 531
Cdd:TIGR02169 565 ellkrrKAGRATFLPLNKMRDERRDLSilsedgvigfavdlvEFDPKYEPafkyvfgdtlvvedieAARRLMGKYRMVTl 644
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 532 --------------TVTEKLIEETKRALKSKT-DAEEKMYSVTKERDDLRNKLKAEEEKGHDLLSKVTILKnrlQSLEAI 596
Cdd:TIGR02169 645 egelfeksgamtggSRAPRGGILFSRSEPAELqRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDAS---RKIGEI 721
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 597 EKDfvKNKLNQDSSKSTAALHQENNKIKELSQEVENLKLKLKDMKA----IEDDLMKTEDEYETLERRYANERDK---AQ 669
Cdd:TIGR02169 722 EKE--IEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEArieeLEEDLHKLEEALNDLEARLSHSRIPeiqAE 799
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 670 FLSQELEHAKMELAKYKLAEKTESSHEqwlfrRLQEEEAKSGHLSREVDALKEKIHEYMATEDlichlqgdhsllqkkln 749
Cdd:TIGR02169 800 LSKLEEEVSRIEARLREIEQKLNRLTL-----EKEYLEKEIQELQEQRIDLKEQIKSIEKEIE----------------- 857
|
730 740 750
....*....|....*....|....*....|....
gi 295424207 750 qqenrnrDLGREIENLTKELERYRHFSKSLRPSL 783
Cdd:TIGR02169 858 -------NLNGKKEELEEELEELEAALRDLESRL 884
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
142-682 |
5.35e-11 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 67.27 E-value: 5.35e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 142 DKVVEKHKESHRRILEQLLMVERSHRQTIMEMEEEKRKHKEYMKKSDEFINLLEQECERLKKLIDQETASQEKKEQekek 221
Cdd:COG1196 234 LRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEE---- 309
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 222 RIKTLKEELTKLKSFALMVVDEQQRLTAQLALQRQKIQALTTSAKETQGKLALAEARAQEEEQKATRLEKELQTQTTEFH 301
Cdd:COG1196 310 RRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELL 389
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 302 QNQDKIMAKLTNEDSQNRQLRQKLAALSRQIDELEETNRSLRKAEEELQDIKDKINKGEYGNSGIMDEVDELRKRVLDME 381
Cdd:COG1196 390 EALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELL 469
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 382 GKDEELIKMEEQCRDLNKRLE--------------------KETVQSKDFKLEVDKLSVRITALEKLEDAL--------- 432
Cdd:COG1196 470 EEAALLEAALAELLEELAEAAarllllleaeadyegflegvKAALLLAGLRGLAGAVAVLIGVEAAYEAALeaalaaalq 549
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 433 -------DKSKQECYSLKCN-------LEKEKMTTKQLSEELESLNARIKELEAIESRLEKTEITLKD--DLTKLKTLTV 496
Cdd:COG1196 550 nivveddEVAAAAIEYLKAAkagratfLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVlgDTLLGRTLVA 629
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 497 MLVDERKTMSEKLKQTEDKL----------QSTTSQLQAEQNKVTTVTEKLIEETKRALKSKTDAEEKmysVTKERDDLR 566
Cdd:COG1196 630 ARLEAALRRAVTLAGRLREVtlegeggsagGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEE---ALLAEEEEE 706
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 567 NKLKAEEEKGHDLLSKVTILKNRLQSLEAIEKDFvKNKLNQDSSKSTAALHQENNKIKELSQEVENLKLKLKDMKAIEdd 646
Cdd:COG1196 707 RELAEAEEERLEEELEEEALEEQLEAEREELLEE-LLEEEELLEEEALEELPEPPDLEELERELERLEREIEALGPVN-- 783
|
570 580 590
....*....|....*....|....*....|....*....
gi 295424207 647 lMKTEDEYETLERRYanerdkaQFLSQE---LEHAKMEL 682
Cdd:COG1196 784 -LLAIEEYEELEERY-------DFLSEQredLEEARETL 814
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
111-434 |
9.66e-11 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 66.23 E-value: 9.66e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 111 KKVLEALQRDAFQAKSAPWQEDIYEKPMNELDKVVEKHKESHRRILEQLlmveRSHRQTIMEMEEEKRKHKEYMKKSDEF 190
Cdd:TIGR02168 701 AELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERI----AQLSKELTELEAEIEELEERLEEAEEE 776
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 191 INLLEQECERLKKLIDQetasQEKKEQEKEKRIKTLKEELTKLKSFALMVVDEQQRLTAQLALQRQKIQALTTSAKETQG 270
Cdd:TIGR02168 777 LAEAEAEIEELEAQIEQ----LKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSE 852
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 271 KLALAEARAQEEEQKATRLEKELQTQTTEFHQNQDKIMAKLTNEDSQNRQLRQKLAALSRQIDELEETNRSLRKAEEELQ 350
Cdd:TIGR02168 853 DIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLE 932
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 351 DIKDKINK------GEYG---------NSGIMDEVDELRKRVLDMEGKDEEL--IKME--EQCRDLNKRLEKETVQSKDF 411
Cdd:TIGR02168 933 GLEVRIDNlqerlsEEYSltleeaealENKIEDDEEEARRRLKRLENKIKELgpVNLAaiEEYEELKERYDFLTAQKEDL 1012
|
330 340
....*....|....*....|...
gi 295424207 412 KlevdklsvriTALEKLEDALDK 434
Cdd:TIGR02168 1013 T----------EAKETLEEAIEE 1025
|
|
| DUF3584 |
pfam12128 |
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ... |
236-775 |
2.41e-10 |
|
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.
Pssm-ID: 432349 [Multi-domain] Cd Length: 1191 Bit Score: 65.24 E-value: 2.41e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 236 FALMVVDEQQRLTAQLALQrqkiqALTTSAKETQgklaLAEARAQEEEQKAT-RLEKELQTQTTEFHQNQDKIMAKLTNE 314
Cdd:pfam12128 243 FTKLQQEFNTLESAELRLS-----HLHFGYKSDE----TLIASRQEERQETSaELNQLLRTLDDQWKEKRDELNGELSAA 313
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 315 DSQNRQLRQKLAALSRQIDELEETNRSLRKAE-EELQDIKDKINKGEygnsgimDEVDELRKRVLDMEGKDEELI-KMEE 392
Cdd:pfam12128 314 DAAVAKDRSELEALEDQHGAFLDADIETAAADqEQLPSWQSELENLE-------ERLKALTGKHQDVTAKYNRRRsKIKE 386
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 393 QCRDLNKRLEKETVQSKDFKleVDKLSVRITALEKLEDALDKS--------KQECYSLKCNLEKEKMTTKQL---SEELE 461
Cdd:pfam12128 387 QNNRDIAGIKDKLAKIREAR--DRQLAVAEDDLQALESELREQleagklefNEEEYRLKSRLGELKLRLNQAtatPELLL 464
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 462 SLNARIKELEAIESRLE---KTEITLKDDLTKLKTLtvmlvdeRKTMSEKLKQTEDKLQSTTSQLQAEQNKVTTVTEKLI 538
Cdd:pfam12128 465 QLENFDERIERAREEQEaanAEVERLQSELRQARKR-------RDQASEALRQASRRLEERQSALDELELQLFPQAGTLL 537
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 539 EETKRALKSKTDAEEKMYSVTK-ERDDLRNKLKAEEEKGHDLLSKVTIlknRLQSLEAIEKDFVKNKLNQDSSKSTAALH 617
Cdd:pfam12128 538 HFLRKEAPDWEQSIGKVISPELlHRTDLDPEVWDGSVGGELNLYGVKL---DLKRIDVPEWAASEEELRERLDKAEEALQ 614
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 618 QENNKIKELSQ-------EVENLKLKLKDMKAI----EDDLMKTEDEYETLERR----YANERDKAQFLSQELEHAKMEL 682
Cdd:pfam12128 615 SAREKQAAAEEqlvqangELEKASREETFARTAlknaRLDLRRLFDEKQSEKDKknkaLAERKDSANERLNSLEAQLKQL 694
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 683 A---KYKLAEKTESSHE---QWLFRRLQEEEAKSGHLSReVDALKEKIHEYMATEDLICHLQGDHSLlqKKLNQQENRNR 756
Cdd:pfam12128 695 DkkhQAWLEEQKEQKREartEKQAYWQVVEGALDAQLAL-LKAAIAARRSGAKAELKALETWYKRDL--ASLGVDPDVIA 771
|
570
....*....|....*....
gi 295424207 757 DLGREIENLTKELERYRHF 775
Cdd:pfam12128 772 KLKREIRTLERKIERIAVR 790
|
|
| PRK02224 |
PRK02224 |
DNA double-strand break repair Rad50 ATPase; |
273-773 |
2.86e-10 |
|
DNA double-strand break repair Rad50 ATPase;
Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 64.68 E-value: 2.86e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 273 ALAEARAQEEEQKatrlEKELQTQTTEFHQNQDKIMAKLTNEDSQNRQLRQKLAALSRQIDELEETNRSLRKAEEELQDI 352
Cdd:PRK02224 188 SLDQLKAQIEEKE----EKDLHERLNGLESELAELDEEIERYEEQREQARETRDEADEVLEEHEERREELETLEAEIEDL 263
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 353 KDKINKGEYGNSGIMDEVDELRKRVLDMEGKD---------------------EELIKMEEQCRDlnkRLEKETVQSKDF 411
Cdd:PRK02224 264 RETIAETEREREELAEEVRDLRERLEELEEERddllaeaglddadaeavearrEELEDRDEELRD---RLEECRVAAQAH 340
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 412 KLEVDKLSVRITALE----KLEDALDKSKQECYSLKCNLEKEKMTTKQLSEELESLNARIK----ELEAIESRLEKTEIT 483
Cdd:PRK02224 341 NEEAESLREDADDLEeraeELREEAAELESELEEAREAVEDRREEIEELEEEIEELRERFGdapvDLGNAEDFLEELREE 420
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 484 LKDDLTKLKTLTVMLVDERKTMSEKLKQTEDKLQSTTSQLQAEQNKVTTVTEKL------------IEETKRALKSKTDA 551
Cdd:PRK02224 421 RDELREREAELEATLRTARERVEEAEALLEAGKCPECGQPVEGSPHVETIEEDRerveeleaeledLEEEVEEVEERLER 500
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 552 EEKMYSVTKERDDLRNKLKAEEEKGHDLLSKVTILKNRLQSL---------EAIEKDFVKNKLNQDSSKSTAALHQENNK 622
Cdd:PRK02224 501 AEDLVEAEDRIERLEERREDLEELIAERRETIEEKRERAEELreraaeleaEAEEKREAAAEAEEEAEEAREEVAELNSK 580
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 623 IKELSQEVENLklklkdmKAIEDDLMKTEDEYETLERRyaNERDKAQflsQELEHAKMElakyKLAEKTEssheqwlfRR 702
Cdd:PRK02224 581 LAELKERIESL-------ERIRTLLAAIADAEDEIERL--REKREAL---AELNDERRE----RLAEKRE--------RK 636
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 295424207 703 LQEEEAKSGHLSREVDALKEKIHEYMATEDlichlqgdhsllqKKLNQQENRNRDLGREI---ENLTKELERYR 773
Cdd:PRK02224 637 RELEAEFDEARIEEAREDKERAEEYLEQVE-------------EKLDELREERDDLQAEIgavENELEELEELR 697
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
241-699 |
2.96e-10 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 64.40 E-value: 2.96e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 241 VDEQQRLTAQLALQRQKIQALTTSAKETQGKLALAEARAQEEEQKATRLEKELQTQttEFHQNQDKIMAKLTNEDSQNRQ 320
Cdd:COG4717 73 LKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLL--PLYQELEALEAELAELPERLEE 150
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 321 LRQKLAALSRQIDELEETNRSLRKAEEELQDIKDKINKGEYGN-SGIMDEVDELRKRVLDMEgkdEELIKMEEQCRDLNK 399
Cdd:COG4717 151 LEERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEElQDLAEELEELQQRLAELE---EELEEAQEELEELEE 227
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 400 RLEKETVQSKDFKLE--VDKLSV------RITALEKLEDALDKSKQEC-----------YSLKCNLEKEKMTTKQLSEEL 460
Cdd:COG4717 228 ELEQLENELEAAALEerLKEARLllliaaALLALLGLGGSLLSLILTIagvlflvlgllALLFLLLAREKASLGKEAEEL 307
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 461 ESLNARikeleaieSRLEKTEIT-LKDDLTKLKTLTVMLVDERKTMSEKLKQTEDKLQSTTSQLQAEQnkvttvteklIE 539
Cdd:COG4717 308 QALPAL--------EELEEEELEeLLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEELQLEE----------LE 369
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 540 ETKRALKSKTDAEekmysvtkERDDLRNKLKAEEEKgHDLLSKVTILKNRLQSL----EAIEKDFVKNKLNQDSSKSTAA 615
Cdd:COG4717 370 QEIAALLAEAGVE--------DEEELRAALEQAEEY-QELKEELEELEEQLEELlgelEELLEALDEEELEEELEELEEE 440
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 616 LHQENNKIKELSQEVENLKLKLKDMKAiEDDLMKTEDEYETLerryanerdKAQFLSQELEHAKMELAKYKLAEKTESSH 695
Cdd:COG4717 441 LEELEEELEELREELAELEAELEQLEE-DGELAELLQELEEL---------KAELRELAEEWAALKLALELLEEAREEYR 510
|
....
gi 295424207 696 EQWL 699
Cdd:COG4717 511 EERL 514
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
243-566 |
4.05e-10 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 64.31 E-value: 4.05e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 243 EQQRLTAQLALQRQKIQALTTSAKETQGKLALAEARAQEEEQKATRLEKELQTQTTEfhqnQDKIMAKLTNEDSQNRQLR 322
Cdd:TIGR02168 685 KIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAE----VEQLEERIAQLSKELTELE 760
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 323 QKLAALSRQIDELEETnrsLRKAEEELQDIKDKINKGEYGNSGIMDEVDELRKRVLDMEG----KDEELIKMEEQCRDLN 398
Cdd:TIGR02168 761 AEIEELEERLEEAEEE---LAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEeaanLRERLESLERRIAATE 837
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 399 KRLEKETVQSKDFKLEVDKLSVRI----TALEKLEDALDKSKQECYSLKCNLEKEKMTTKQLSEELESLNARIKELE--- 471
Cdd:TIGR02168 838 RRLEDLEEQIEELSEDIESLAAEIeeleELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRrel 917
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 472 --------AIESRLEKTEITLKDDLTKLKTLTVMLVDERKTMSEKLKQTEDKLQSTTSQLQAEQNKVTTVTEKLIEETKR 543
Cdd:TIGR02168 918 eelreklaQLELRLEGLEVRIDNLQERLSEEYSLTLEEAEALENKIEDDEEEARRRLKRLENKIKELGPVNLAAIEEYEE 997
|
330 340
....*....|....*....|...
gi 295424207 544 ALKSKTDAEEKMYSVTKERDDLR 566
Cdd:TIGR02168 998 LKERYDFLTAQKEDLTEAKETLE 1020
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
343-708 |
6.55e-10 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 63.42 E-value: 6.55e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 343 RKAEEELQDIKDKINKgeygnsgIMDEVDELRKRVldmegkdEELikmEEQCRDLNKRLE-KETVQSKDFKLEVDKLSVR 421
Cdd:COG1196 175 EEAERKLEATEENLER-------LEDILGELERQL-------EPL---ERQAEKAERYRElKEELKELEAELLLLKLREL 237
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 422 ITALEKLEDALDKSKQECYSLKCNLEKEKMTTKQLSEELESLNARIKELEAIESRLEKTEITLKDDLTKLKtltvmlvDE 501
Cdd:COG1196 238 EAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLE-------ER 310
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 502 RKTMSEKLKQTEDKLQSTTSQLQAEQNKVTTVTEKLIEETKR---ALKSKTDAEEKMYSVTKERDDLRNKLKAEEEKGHD 578
Cdd:COG1196 311 RRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEEleeAEAELAEAEEALLEAEAELAEAEEELEELAEELLE 390
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 579 LLSKVTILKNRLQSLEAIEKDFVKNKLNQDSSKSTAALHQENNKIKELSQEVENLKLKLKDMKAIEDDLMKTEDEYETLE 658
Cdd:COG1196 391 ALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLE 470
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|
gi 295424207 659 RRYANERDKAQFLSQELEHAKMELAKYKLAEKTESSHEQWLFRRLQEEEA 708
Cdd:COG1196 471 EAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLR 520
|
|
| Myosin_tail_1 |
pfam01576 |
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ... |
225-692 |
2.08e-09 |
|
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.
Pssm-ID: 460256 [Multi-domain] Cd Length: 1081 Bit Score: 62.11 E-value: 2.08e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 225 TLKEELTKLKSFALMVVDEQQRLTAQLALQRQKIQALTTSAKETQGKLALAEARAQEEEQKATRLEKELQTQTtEFHQNQ 304
Cdd:pfam01576 128 TTEAKIKKLEEDILLLEDQNSKLSKERKLLEERISEFTSNLAEEEEKAKSLSKLKNKHEAMISDLEERLKKEE-KGRQEL 206
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 305 DKIMAKLTNEDSQnrqLRQKLAALSRQIDELEEtnrSLRKAEEELQDIKDKINKGEYGNSGIMDEVDELRKRVL----DM 380
Cdd:pfam01576 207 EKAKRKLEGESTD---LQEQIAELQAQIAELRA---QLAKKEEELQAALARLEEETAQKNNALKKIRELEAQISelqeDL 280
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 381 EGKDEELIKMEEQCRDLNKRLEketvqskdfklevdklsvritALE-KLEDALD----------KSKQECYSLKCNLEKE 449
Cdd:pfam01576 281 ESERAARNKAEKQRRDLGEELE---------------------ALKtELEDTLDttaaqqelrsKREQEVTELKKALEEE 339
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 450 -KMTTKQLSE-------ELESLNARIKELEAIESRLEKTEITLKDDLTKLKTltvmlvdERKTMSEKLKQTEDKLQSTTS 521
Cdd:pfam01576 340 tRSHEAQLQEmrqkhtqALEELTEQLEQAKRNKANLEKAKQALESENAELQA-------ELRTLQQAKQDSEHKRKKLEG 412
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 522 QLQAEQNKVTtvteklieETKRAlksKTDAEEKMYSVTKERDDLRNKLKAEEEKGHDLLSKVTILKNRLQSLEAIEKDFV 601
Cdd:pfam01576 413 QLQELQARLS--------ESERQ---RAELAEKLSKLQSELESVSSLLNEAEGKNIKLSKDVSSLESQLQDTQELLQEET 481
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 602 KNKLN---------QDSSKSTAALHQENNKIKELSQEVENLKLKLKDMKAIEDDLMKTEDEYETLERRYANERDKA--QF 670
Cdd:pfam01576 482 RQKLNlstrlrqleDERNSLQEQLEEEEEAKRNVERQLSTLQAQLSDMKKKLEEDAGTLEALEEGKKRLQRELEALtqQL 561
|
490 500
....*....|....*....|..
gi 295424207 671 LSQELEHAKMELAKYKLAEKTE 692
Cdd:pfam01576 562 EEKAAAYDKLEKTKNRLQQELD 583
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
315-674 |
2.79e-09 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 61.62 E-value: 2.79e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 315 DSQNRQLRQKLAALSRQIDELEETNRSLRKAEEELQDIKDKinKGEYgnsgimdevDELRKRVLDMEGKD--EELIKMEE 392
Cdd:TIGR02169 169 DRKKEKALEELEEVEENIERLDLIIDEKRQQLERLRREREK--AERY---------QALLKEKREYEGYEllKEKEALER 237
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 393 QCRDLNKRLEKETVQSKDFKLEVDKLSVRITALEKLEDALDKS------------KQECYSLKCNLEKEKMTTKQLSEEL 460
Cdd:TIGR02169 238 QKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKikdlgeeeqlrvKEKIGELEAEIASLERSIAEKEREL 317
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 461 ESLNARIKELEAIESRLEKTEITLKDDLTKLKTltvmlvdERKTMSEKLKQTEDKLQSTTSQLQAEQNKVTTvtekLIEE 540
Cdd:TIGR02169 318 EDAEERLAKLEAEIDKLLAEIEELEREIEEERK-------RRDKLTEEYAELKEELEDLRAELEEVDKEFAE----TRDE 386
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 541 TKRALKSKTDAEEKMYSVTKERDDLRNKLKAEEEKGHDLLSKVTILKNRLQSLEAIEKDFVKnklnqdsskstaalhqen 620
Cdd:TIGR02169 387 LKDYREKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKAL------------------ 448
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*...
gi 295424207 621 nKIKELSQEVENLKLKLKDMK----AIEDDLMKTEDEYETLERRYANERDKAQFLSQE 674
Cdd:TIGR02169 449 -EIKKQEWKLEQLAADLSKYEqelyDLKEEYDRVEKELSKLQRELAEAEAQARASEER 505
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
222-404 |
4.80e-09 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 59.78 E-value: 4.80e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 222 RIKTLKEELTKLKSfalmvvdEQQRLTAQLALQRQKIQALTTSAKETQGKLALAEARAQEEEQKATRLEKELQTQTTEF- 300
Cdd:COG4942 35 EIAELEKELAALKK-------EEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEELa 107
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 301 --------HQNQDKIMAKLTNEDSQ------------NRQLRQKLAALSRQIDELEETNRSLRKAEEELQDIKDKINKGE 360
Cdd:COG4942 108 ellralyrLGRQPPLALLLSPEDFLdavrrlqylkylAPARREQAEELRADLAELAALRAELEAERAELEALLAELEEER 187
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 295424207 361 YGNSGIMDE----VDELRKRVLDMEGKDEELIKMEEQCRDLNKRLEKE 404
Cdd:COG4942 188 AALEALKAErqklLARLEKELAELAAELAELQQEAEELEALIARLEAE 235
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
124-471 |
6.61e-09 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 60.47 E-value: 6.61e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 124 AKSAPWQEDIYEKPmNELDKVVEKHKESHRRILEQLLMVERSHRQT------IMEMEEEKRKHKEYMKKSDEFINLLEQE 197
Cdd:TIGR02169 674 AELQRLRERLEGLK-RELSSLQSELRRIENRLDELSQELSDASRKIgeiekeIEQLEQEEEKLKERLEELEEDLSSLEQE 752
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 198 CERLKklidQETASQEKKEQEKEKRIKTLKEELTKLK-SFALMVVDEQQRLTAQLALQRQKIQALTTSAKETQGKLALAE 276
Cdd:TIGR02169 753 IENVK----SELKELEARIEELEEDLHKLEEALNDLEaRLSHSRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEK 828
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 277 ARAQEEEQKATRLEKELQTQTTEFHQNQD-------KIMAKLTNEDSQNRQLRQKLAALSRQIDELEETNRSLRKAEEEL 349
Cdd:TIGR02169 829 EYLEKEIQELQEQRIDLKEQIKSIEKEIEnlngkkeELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEEL 908
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 350 QdikdkinkgeygnsgimDEVDELRKRVLDMEGKDEELIKMEEQCRDLNKRLE---KETVQSKDFKLEVDKLSVRITALE 426
Cdd:TIGR02169 909 E-----------------AQIEKKRKRLSELKAKLEALEEELSEIEDPKGEDEeipEEELSLEDVQAELQRVEEEIRALE 971
|
330 340 350 360
....*....|....*....|....*....|....*....|....*
gi 295424207 427 KLEDALDKSKQECYSLKCNLEKEKMTtkqLSEELESLNARIKELE 471
Cdd:TIGR02169 972 PVNMLAIQEYEEVLKRLDELKEKRAK---LEEERKAILERIEEYE 1013
|
|
| SCP-1 |
pfam05483 |
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ... |
125-769 |
1.06e-08 |
|
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.
Pssm-ID: 114219 [Multi-domain] Cd Length: 787 Bit Score: 59.35 E-value: 1.06e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 125 KSAPWQEDIYEKPMNELDKVVEKHK--ESHRRILEQLlmvERSHRQTIMEMEEEKRKHKEYMKKSD---EFINLLEQECE 199
Cdd:pfam05483 89 KIKKWKVSIEAELKQKENKLQENRKiiEAQRKAIQEL---QFENEKVSLKLEEEIQENKDLIKENNatrHLCNLLKETCA 165
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 200 RLKKLIDQETASQEKKEQEKEKRIKTLKEELTKLKSFALMVVDEQQRLTAQLALQRQKIQALTtsaKETQGKLALAEARA 279
Cdd:pfam05483 166 RSAEKTKKYEYEREETRQVYMDLNNNIEKMILAFEELRVQAENARLEMHFKLKEDHEKIQHLE---EEYKKEINDKEKQV 242
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 280 QEEEQKATRLEKELQTQTTEFHQNQDKIMAKLTNEDSQNRQLRQKLAALSRQIDELEETNRSLRKA-------EEELQDI 352
Cdd:pfam05483 243 SLLLIQITEKENKMKDLTFLLEESRDKANQLEEKTKLQDENLKELIEKKDHLTKELEDIKMSLQRSmstqkalEEDLQIA 322
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 353 KDKINKGEYGNSGIMDEVDELRK-RVLDMEGKDEELIKMEEQCRDLNKRLEKETVQSKDFKLEVDKLSVRITALEKLEDA 431
Cdd:pfam05483 323 TKTICQLTEEKEAQMEELNKAKAaHSFVVTEFEATTCSLEELLRTEQQRLEKNEDQLKIITMELQKKSSELEEMTKFKNN 402
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 432 LDKSKQECYSLKCNLEKEKMTTKQLSEELESLNARIKELEAIESRLEKTEITLKDDLTKLKTLT---VMLVDERKTMSEK 508
Cdd:pfam05483 403 KEVELEELKKILAEDEKLLDEKKQFEKIAEELKGKEQELIFLLQAREKEIHDLEIQLTAIKTSEehyLKEVEDLKTELEK 482
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 509 LKQTEDKLQSTTSQLQAEQNKVTTVTEKLIEETK--------------RALKSKTDAEEK-------MYSVTKE----RD 563
Cdd:pfam05483 483 EKLKNIELTAHCDKLLLENKELTQEASDMTLELKkhqediinckkqeeRMLKQIENLEEKemnlrdeLESVREEfiqkGD 562
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 564 DLRNKLKAEEEKGHDLLSKVTILKNRLQSLEAIEKDFVKNKLNQdsSKSTAALHQENNKIKELSQeVENLKLKLKDMKA- 642
Cdd:pfam05483 563 EVKCKLDKSEENARSIEYEVLKKEKQMKILENKCNNLKKQIENK--NKNIEELHQENKALKKKGS-AENKQLNAYEIKVn 639
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 643 -IEDDLMKTEDEYETLERRYANERDKAQfLSQELEHAKMELAKYKLAEKTessheqwlfrRLQEE-EAKSGHLSREVDAL 720
Cdd:pfam05483 640 kLELELASAKQKFEEIIDNYQKEIEDKK-ISEEKLLEEVEKAKAIADEAV----------KLQKEiDKRCQHKIAEMVAL 708
|
650 660 670 680 690
....*....|....*....|....*....|....*....|....*....|
gi 295424207 721 KEK-IHEYmatEDLICHLQGDHSLLQKKLNQQENRNRDLGREIENLTKEL 769
Cdd:pfam05483 709 MEKhKHQY---DKIIEERDSELGLYKNKEQEQSSAKAALEIELSNIKAEL 755
|
|
| PRK05771 |
PRK05771 |
V-type ATP synthase subunit I; Validated |
363-676 |
1.53e-08 |
|
V-type ATP synthase subunit I; Validated
Pssm-ID: 235600 [Multi-domain] Cd Length: 646 Bit Score: 58.79 E-value: 1.53e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 363 NSGIMdEVDELRKrvldmEGKDEELIKMEEQCRDLNKRLEK-ETVQSKDFKLEVDKLSVRITALEKLEDALDKSKQEcys 441
Cdd:PRK05771 27 ELGVV-HIEDLKE-----ELSNERLRKLRSLLTKLSEALDKlRSYLPKLNPLREEKKKVSVKSLEELIKDVEEELEK--- 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 442 lkcnLEKEkmtTKQLSEELESLNARIKELEAIESRLEKteitlkddltkLKTLTVMLVDERKtmseklkqtedklqstts 521
Cdd:PRK05771 98 ----IEKE---IKELEEEISELENEIKELEQEIERLEP-----------WGNFDLDLSLLLG------------------ 141
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 522 qlqaeqNKVTTVTEKLIEETKralksktdaeekmYSVTKERDDLRNKLKAEEEKGHDLLSkVTILKNRLQSLEAI--EKD 599
Cdd:PRK05771 142 ------FKYVSVFVGTVPEDK-------------LEELKLESDVENVEYISTDKGYVYVV-VVVLKELSDEVEEElkKLG 201
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 295424207 600 FVKNKLNqDSSKSTAALHQENNKIKELSQEVENLKLKLKDMKAIEDDLMKTEDEYetlerrYANERDKAQFLSQELE 676
Cdd:PRK05771 202 FERLELE-EEGTPSELIREIKEELEEIEKERESLLEELKELAKKYLEELLALYEY------LEIELERAEALSKFLK 271
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
283-690 |
2.25e-08 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 58.49 E-value: 2.25e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 283 EQKATRLEKELQTQTTEFHQNQDKI----------MAKLTNEDSQNRQLRQKLAALSRQI----DELEETNRSLRKAEEE 348
Cdd:TIGR04523 32 DTEEKQLEKKLKTIKNELKNKEKELknldknlnkdEEKINNSNNKIKILEQQIKDLNDKLkknkDKINKLNSDLSKINSE 111
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 349 LQDIKDKINKGEygnsgimDEVDELRKrvldmegkdeELIKMEEQCRDLNKRLEKETVQSKDFKLEVDKLSVRITALEKL 428
Cdd:TIGR04523 112 IKNDKEQKNKLE-------VELNKLEK----------QKKENKKNIDKFLTEIKKKEKELEKLNNKYNDLKKQKEELENE 174
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 429 EDALDKSKQECYSLKCNLEKEKMTTKQLSEELESLNARIKELEAIESRLEKTEITLKDDLTKLKTLTVMLVDERKTMSEK 508
Cdd:TIGR04523 175 LNLLEKEKLNIQKNIDKIKNKLLKLELLLSNLKKKIQKNKSLESQISELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQ 254
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 509 LKQTEDKLQSTTSQLQAEQNKVTTVTEKLIEETKRALKSKTDAE---------------EKMYSVTKERDDLRNKLKAEE 573
Cdd:TIGR04523 255 LNQLKDEQNKIKKQLSEKQKELEQNNKKIKELEKQLNQLKSEISdlnnqkeqdwnkelkSELKNQEKKLEEIQNQISQNN 334
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 574 EKGHDLLSKVTILKNRLQSLEAiekdfVKNKLNQDSSKSTAALHQENNKIKELSQEVENLKLKLKDM-----------KA 642
Cdd:TIGR04523 335 KIISQLNEQISQLKKELTNSES-----ENSEKQRELEEKQNEIEKLKKENQSYKQEIKNLESQINDLeskiqnqeklnQQ 409
|
410 420 430 440
....*....|....*....|....*....|....*....|....*...
gi 295424207 643 IEDDLMKTEDEYETLERRYANERDKAQFLSQELEHAKMELAKYKLAEK 690
Cdd:TIGR04523 410 KDEQIKKLQQEKELLEKEIERLKETIIKNNSEIKDLTNQDSVKELIIK 457
|
|
| rad50 |
TIGR00606 |
rad50; All proteins in this family for which functions are known are involvedin recombination, ... |
188-707 |
3.65e-08 |
|
rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).
Pssm-ID: 129694 [Multi-domain] Cd Length: 1311 Bit Score: 58.13 E-value: 3.65e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 188 DEFINLLEQECERLKKLIDQETASQEKKEQEKEKRIKTLKEELTKLKSFALMVVDEQQRLTAQLALQRQKIQALTTSAKE 267
Cdd:TIGR00606 393 KNFHTLVIERQEDEAKTAAQLCADLQSKERLKQEQADEIRDEKKGLGRTIELKKEILEKKQEELKFVIKELQQLEGSSDR 472
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 268 TQGKlalaEARAQEEEQKATRLEKELQTQTTEfhQNQDKIMAKLTNEDSQNRQLRQKLAALSRQIDELEETNRSLRKAEE 347
Cdd:TIGR00606 473 ILEL----DQELRKAERELSKAEKNSLTETLK--KEVKSLQNEKADLDRKLRKLDQEMEQLNHHTTTRTQMEMLTKDKMD 546
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 348 ELQDIKDKINKGEYGNSGIMDEVDELRKRVLDMEGKDEELIKMEEQCRDLNKRLEKETVQSKDFKLEVDKLSVRITALEK 427
Cdd:TIGR00606 547 KDEQIRKIKSRHSDELTSLLGYFPNKKQLEDWLHSKSKEINQTRDRLAKLNKELASLEQNKNHINNELESKEEQLSSYED 626
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 428 ----------LEDALDKSKQECYSLKCNLEKEKMTTKQLSEELESLNARIKELEAIESRLEKTEITLKDDLTKLKTLTVM 497
Cdd:TIGR00606 627 klfdvcgsqdEESDLERLKEEIEKSSKQRAMLAGATAVYSQFITQLTDENQSCCPVCQRVFQTEAELQEFISDLQSKLRL 706
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 498 LVDERKTMSEKLKQTEDKLQSTTSQLQAEQNKVTTVtEKLIEETKRALKSKTDAEEKMYSVTKERDDLRNKLKAEEEKGH 577
Cdd:TIGR00606 707 APDKLKSTESELKKKEKRRDEMLGLAPGRQSIIDLK-EKEIPELRNKLQKVNRDIQRLKNDIEEQETLLGTIMPEEESAK 785
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 578 DLLSKVTILKNRLQSLEAIEKDFVKNKLNQDSSKSTAALHQENNKIKE-------LSQEVENLKLKLKDMKAIEDDLMKT 650
Cdd:TIGR00606 786 VCLTDVTIMERFQMELKDVERKIAQQAAKLQGSDLDRTVQQVNQEKQEkqheldtVVSKIELNRKLIQDQQEQIQHLKSK 865
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 295424207 651 EDEYETLERRYANERDKAQFLSQELEHAKMELAK----YKLAEKTESSHEQWLFRRLQEEE 707
Cdd:TIGR00606 866 TNELKSEKLQIGTNLQRRQQFEEQLVELSTEVQSlireIKDAKEQDSPLETFLEKDQQEKE 926
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
384-759 |
3.83e-08 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 57.76 E-value: 3.83e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 384 DEELIKMEEQCRDLNKRLEKETVQS------KDFKLEVDKLSVRITALEKLEdaldkskqecysLKCNLEKEKMTTKQLS 457
Cdd:TIGR02168 185 RENLDRLEDILNELERQLKSLERQAekaeryKELKAELRELELALLVLRLEE------------LREELEELQEELKEAE 252
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 458 EELESLNARIKELEA--IESRLEKTEitLKDDLTKLKTLTVMLVDERKTMSEKLKQTEDKLQsttsQLQAEQNKVTTVTE 535
Cdd:TIGR02168 253 EELEELTAELQELEEklEELRLEVSE--LEEEIEELQKELYALANEISRLEQQKQILRERLA----NLERQLEELEAQLE 326
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 536 KLIEETKRALKSKTDAEEKMYSVTKERDDLRNKLKAEEEKGHDLLSKVTILKNRLQSLEaiekdfvknklnqdsskstAA 615
Cdd:TIGR02168 327 ELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLR-------------------SK 387
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 616 LHQENNKIKELSQEVENLKLKLKDmkaIEDDLMKTEDEYETLERRYanERDKAQFLSQELEHAKMELAKyklAEKTESSH 695
Cdd:TIGR02168 388 VAQLELQIASLNNEIERLEARLER---LEDRRERLQQEIEELLKKL--EEAELKELQAELEELEEELEE---LQEELERL 459
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 295424207 696 EQWLfRRLQEEEAKsghLSREVDALKEKIHEYMATEDLICHLQGDHSLLQKKLNQQENRNRDLG 759
Cdd:TIGR02168 460 EEAL-EELREELEE---AEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLS 519
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
111-575 |
4.52e-08 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 57.84 E-value: 4.52e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 111 KKVLEALQRDAFQAKSapwQEDIYEKPMNELDKVVEKHKESHRRILEQLLMVERSHRQTIMEMEEEKRKHKEYMKKSDEf 190
Cdd:PTZ00121 1314 AKKADEAKKKAEEAKK---KADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEE- 1389
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 191 inllEQECERLKKlidqetasqekkeqekekriktlKEELTKLKSFALMVVDEQQRLTAQLALQRQKIQALTTSAKETQG 270
Cdd:PTZ00121 1390 ----KKKADEAKK-----------------------KAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEE 1442
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 271 KLALAEARAQEEEQKATrleKELQTQTTEFHQNQDkiMAKLTNEDSQNRQLRQKLAALSRQIDELEETNRSLRKAeEELQ 350
Cdd:PTZ00121 1443 AKKADEAKKKAEEAKKA---EEAKKKAEEAKKADE--AKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKA-DEAK 1516
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 351 DIKDKINKGEYGNSGIMDEVDELRK----RVLDMEGKDEELIKMEEQCRDLNKRLEKETVQSKDFKLEVDKLS--VRITA 424
Cdd:PTZ00121 1517 KAEEAKKADEAKKAEEAKKADEAKKaeekKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAeeARIEE 1596
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 425 LEKLEDALDKSKQEcYSLKCNLEKEKMTTKQLSEELESLNARIKELEAIESRlEKTEITLKDDLTKLKTLTVML-VDERK 503
Cdd:PTZ00121 1597 VMKLYEEEKKMKAE-EAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKK-KAEELKKAEEENKIKAAEEAKkAEEDK 1674
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 295424207 504 TMSEKLKQTEDKLQSTTSQLQ---AEQNKVTTVTEKLIEETKRALKSKTDAEEKMYSVTK-ERDDLRNKLKAEEEK 575
Cdd:PTZ00121 1675 KKAEEAKKAEEDEKKAAEALKkeaEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEaKKEAEEDKKKAEEAK 1750
|
|
| SMC_N |
pfam02463 |
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
224-565 |
1.06e-07 |
|
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 56.52 E-value: 1.06e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 224 KTLKEELTKLKSFALMVVDEQQRLTAQLALQRQKIQALTTSAKETQGKLALAEARAQEEEQKATRLEKELQTQTTEFHQN 303
Cdd:pfam02463 662 SEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLADRVQEAQDKINEELKLL 741
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 304 QDKIMAKLTNEDSQNRQLRQKLA----ALSRQIDELEETNRSLRKAEEELQDIKDKINKGEYGNSGIMDEVDELRKRVLD 379
Cdd:pfam02463 742 KQKIDEEEEEEEKSRLKKEEKEEekseLSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEELRALEEELKEEAELLEEEQ 821
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 380 MEGKDEELIKMEEQCRDLNKRLEKETVQSKDFKLEVDKLSVRITALEKLEDALDKSKQECYSLKCNLEKEKMTTKQLSEE 459
Cdd:pfam02463 822 LLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEELLQELLLKEEELEEQKLKDELESKEEKEKEEKKE 901
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 460 LESLNARIKELEAIESRLEKTEITLKDDLTKLKTLTVMLVDERKTMSEKLKQTEDKLQSTTSQLQAEQNKVTTVTEKLIE 539
Cdd:pfam02463 902 LEEESQKLNLLEEKENEIEERIKEEAEILLKYEEEPEELLLEEADEKEKEENNKEEEEERNKRLLLAKEELGKVNLMAIE 981
|
330 340
....*....|....*....|....*.
gi 295424207 540 ETKRALKSKTDAEEKMYSVTKERDDL 565
Cdd:pfam02463 982 EFEEKEERYNKDELEKERLEEEKKKL 1007
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
272-544 |
1.23e-07 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 55.16 E-value: 1.23e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 272 LALAEARAQEEEQKAtrLEKELQtqttEFHQNQDKIMAKLTNEDSQNRQLRQKLAALSRQIDELEetnRSLRKAEEELQD 351
Cdd:COG4942 10 LLALAAAAQADAAAE--AEAELE----QLQQEIAELEKELAALKKEEKALLKQLAALERRIAALA---RRIRALEQELAA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 352 IKDKINKGEygnsgimDEVDELRKRvldmegkdeelikMEEQCRDLNKRLEKETVQSKDFKLEVdklsvritaLEKLEDA 431
Cdd:COG4942 81 LEAELAELE-------KEIAELRAE-------------LEAQKEELAELLRALYRLGRQPPLAL---------LLSPEDF 131
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 432 LDKSKqecyslkcNLEKEKMTTKQLSEELESLNARIKELEAIESRLEKTEITLKDDLTKLKTLTVML---VDERKTMSEK 508
Cdd:COG4942 132 LDAVR--------RLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEALLAELEEERAALealKAERQKLLAR 203
|
250 260 270
....*....|....*....|....*....|....*.
gi 295424207 509 LKQTEDKLQSTTSQLQAEQNKVTTVTEKLIEETKRA 544
Cdd:COG4942 204 LEKELAELAAELAELQQEAEELEALIARLEAEAAAA 239
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
170-512 |
1.61e-07 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 55.80 E-value: 1.61e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 170 IMEMEEEKRKHKEYMKKSDEFINLLE---QECERLKKLIDQETASQEKKEQEKEKRIKTLKEELTKLKSfalmvvdEQQR 246
Cdd:TIGR04523 372 IEKLKKENQSYKQEIKNLESQINDLEskiQNQEKLNQQKDEQIKKLQQEKELLEKEIERLKETIIKNNS-------EIKD 444
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 247 LTAQLALQRQKIQALTTSAKETQGKLALAEARAQEEEQKATRLEKELQTQTTEfhqnqdkimakLTNEDSQNRQLRQKLA 326
Cdd:TIGR04523 445 LTNQDSVKELIIKNLDNTRESLETQLKVLSRSINKIKQNLEQKQKELKSKEKE-----------LKKLNEEKKELEEKVK 513
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 327 ALSRQIDELEETNRSL----RKAEEELQDIKDKINKGEYG--NSGIMDEVDELRKRVLDMEGKDEELIKMEEQCRDLNKR 400
Cdd:TIGR04523 514 DLTKKISSLKEKIEKLesekKEKESKISDLEDELNKDDFElkKENLEKEIDEKNKEIEELKQTQKSLKKKQEEKQELIDQ 593
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 401 LEKEtvqskdFKLEVDKLSVRITALEKLEDALDKSKQEcyslKCNLEKEKMTTKQLSEELEslnariKELEAIESRLEKT 480
Cdd:TIGR04523 594 KEKE------KKDLIKEIEEKEKKISSLEKELEKAKKE----NEKLSSIIKNIKSKKNKLK------QEVKQIKETIKEI 657
|
330 340 350
....*....|....*....|....*....|..
gi 295424207 481 EITLKDDLTKLKTLTVMLVDERKTMSEKLKQT 512
Cdd:TIGR04523 658 RNKWPEIIKKIKESKTKIDDIIELMKDWLKEL 689
|
|
| GumC |
COG3206 |
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis]; |
445-683 |
1.66e-07 |
|
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 442439 [Multi-domain] Cd Length: 687 Bit Score: 55.41 E-value: 1.66e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 445 NLEKEKMTTKQLSEELEslnariKELEAIESRLEKTEITLKDdlTKLKTLTVMLVDERKTMSEKLKQTEDKLQSTTSQLQ 524
Cdd:COG3206 165 NLELRREEARKALEFLE------EQLPELRKELEEAEAALEE--FRQKNGLVDLSEEAKLLLQQLSELESQLAEARAELA 236
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 525 AEQNKVTTVTEKLieETKRALKSKTDAEEKMYSVTKERDDLRNKLKAEEEKGHDLLSKVTILKNRLQSLEAiekdfvknK 604
Cdd:COG3206 237 EAEARLAALRAQL--GSGPDALPELLQSPVIQQLRAQLAELEAELAELSARYTPNHPDVIALRAQIAALRA--------Q 306
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 295424207 605 LNQDSSKSTAALHQEnnkIKELSQEVENLKLKLKDMKAIEDDLMKTEDEYETLERRYANERDKAQFLSQELEHAKMELA 683
Cdd:COG3206 307 LQQEAQRILASLEAE---LEALQAREASLQAQLAQLEARLAELPELEAELRRLEREVEVARELYESLLQRLEEARLAEA 382
|
|
| DUF3584 |
pfam12128 |
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ... |
69-782 |
2.10e-07 |
|
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.
Pssm-ID: 432349 [Multi-domain] Cd Length: 1191 Bit Score: 55.61 E-value: 2.10e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 69 DLLFLLSILEGEL-QARDEVIGILRAEKIDLALLEAQYGFVTPKKvLEALQRDAFQAKSAPWQEDIYEKPMNELDKVVEK 147
Cdd:pfam12128 287 ELNQLLRTLDDQWkEKRDELNGELSAADAAVAKDRSELEALEDQH-GAFLDADIETAAADQEQLPSWQSELENLEERLKA 365
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 148 HKESHRRILEQ-----LLMVERSHRQtIMEMEEEKRKHKEYMKKSDEFI-NLLEQECERLKKLIDQETASQEKKEQEKEK 221
Cdd:pfam12128 366 LTGKHQDVTAKynrrrSKIKEQNNRD-IAGIKDKLAKIREARDRQLAVAeDDLQALESELREQLEAGKLEFNEEEYRLKS 444
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 222 RIKTLKEELtklksfalmvvdEQQRLTAQLALQRQKIQALTTSAKETQGKLALAEARAQEEEQKATrlekelqtqttefh 301
Cdd:pfam12128 445 RLGELKLRL------------NQATATPELLLQLENFDERIERAREEQEAANAEVERLQSELRQAR-------------- 498
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 302 qnqdkimaklTNEDSQNRQLRQKLAALSRQIDELEETNRSLRKAEEELQDIkdkinkgeygnsgimdevdeLRKRVLDME 381
Cdd:pfam12128 499 ----------KRRDQASEALRQASRRLEERQSALDELELQLFPQAGTLLHF--------------------LRKEAPDWE 548
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 382 GKDEELIKMEEQCR-DLNKRLEKETVQSKD--FKLEVDKLSVRITALEKLEDALdksKQECYSLKCNLEKEKMTTKQLSE 458
Cdd:pfam12128 549 QSIGKVISPELLHRtDLDPEVWDGSVGGELnlYGVKLDLKRIDVPEWAASEEEL---RERLDKAEEALQSAREKQAAAEE 625
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 459 ELESLNARIKELEAIESRLEKteiTLKDDLTKLKTLTVMLVDERKTMSEKLKQTEDKLQSTTSQLQAEQNKVTTVTEKLI 538
Cdd:pfam12128 626 QLVQANGELEKASREETFART---ALKNARLDLRRLFDEKQSEKDKKNKALAERKDSANERLNSLEAQLKQLDKKHQAWL 702
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 539 EETKR-ALKSKTDAEEKMYSVTKERDDLRNKLKAEeekghdLLSKVTILKNRLQSLEaiekdfvknklnQDSSKSTAALH 617
Cdd:pfam12128 703 EEQKEqKREARTEKQAYWQVVEGALDAQLALLKAA------IAARRSGAKAELKALE------------TWYKRDLASLG 764
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 618 QENNKIKELSQEVENLKLKLKDMKAIEDDLMKTEDEYetlERRYANERDKAQFLSQELEHAKMELaKYKLAEKTESSHeq 697
Cdd:pfam12128 765 VDPDVIAKLKREIRTLERKIERIAVRRQEVLRYFDWY---QETWLQRRPRLATQLSNIERAISEL-QQQLARLIADTK-- 838
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 698 wlfRRLQEEEAKSGHLSREVDALKEKIHEYMATEDLICHL-------QGDHSlLQKKLNQQENRNRDLGREIENLTKELE 770
Cdd:pfam12128 839 ---LRRAKLEMERKASEKQQVRLSENLRGLRCEMSKLATLkedanseQAQGS-IGERLAQLEDLKLKRDYLSESVKKYVE 914
|
730
....*....|..
gi 295424207 771 RYRHFSKSLRPS 782
Cdd:pfam12128 915 HFKNVIADHSGS 926
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
323-734 |
2.36e-07 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 55.16 E-value: 2.36e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 323 QKLAALSRQIDELEETNRSLRKAEEELQDIKDKINKGEygnsgimDEVDELRKRVLDMEgKDEELIKMEEQCRDLNKRLE 402
Cdd:COG4717 71 KELKELEEELKEAEEKEEEYAELQEELEELEEELEELE-------AELEELREELEKLE-KLLQLLPLYQELEALEAELA 142
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 403 KETVQSKDFKLEVDKLSVRITALEKLEDALDKSKQECYSLKCNL-EKEKMTTKQLSEELESLNARIKELEAIESRLEKTE 481
Cdd:COG4717 143 ELPERLEELEERLEELRELEEELEELEAELAELQEELEELLEQLsLATEEELQDLAEELEELQQRLAELEEELEEAQEEL 222
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 482 ITLKDDLTKLKTLTVMLVDERKTMSEK-----------LKQTEDKLQSTTSQLQA--------------EQNKVTTVTEK 536
Cdd:COG4717 223 EELEEELEQLENELEAAALEERLKEARlllliaaallaLLGLGGSLLSLILTIAGvlflvlgllallflLLAREKASLGK 302
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 537 LIEETkRALKSKTDAEEKMYSVTKERDDLRNKLKAEE--------EKGHDLLSKVTILKNRLQsLEAIEKDFVK--NKLN 606
Cdd:COG4717 303 EAEEL-QALPALEELEEEELEELLAALGLPPDLSPEEllelldriEELQELLREAEELEEELQ-LEELEQEIAAllAEAG 380
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 607 QDSSKSTAALHQENNKIKELSQEVENLKLKLKDMKAIEDDLMKTEDEyETLERRYANERDKAQFLSQELEHAKMELAKYK 686
Cdd:COG4717 381 VEDEEELRAALEQAEEYQELKEELEELEEQLEELLGELEELLEALDE-EELEEELEELEEELEELEEELEELREELAELE 459
|
410 420 430 440
....*....|....*....|....*....|....*....|....*....
gi 295424207 687 LA-EKTESSHEqwLFRRLQEEEaksgHLSREVDALKEKIHEYMATEDLI 734
Cdd:COG4717 460 AElEQLEEDGE--LAELLQELE----ELKAELRELAEEWAALKLALELL 502
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
172-575 |
3.88e-07 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 54.39 E-value: 3.88e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 172 EMEEEKRKHKEYMKKSDEfINLLEQECERLKKlidqetasqekkeqekekRIKTLKEELTKLKSF--ALMVVDEQQRLTA 249
Cdd:COG4717 79 ELKEAEEKEEEYAELQEE-LEELEEELEELEA------------------ELEELREELEKLEKLlqLLPLYQELEALEA 139
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 250 QLALQRQKIQALTTSAKETQGKLALAEARAQEEEQKATRLEKELQTQTTEFHQNQDKIMAKLTNEDSQNRQLRQKLAALS 329
Cdd:COG4717 140 ELAELPERLEELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQ 219
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 330 RQIDELEEtNRSLRKAEEELQDIKDKINKGEY---------GNSGIMDEVDELRKRV------------LDMEGKDEELI 388
Cdd:COG4717 220 EELEELEE-ELEQLENELEAAALEERLKEARLllliaaallALLGLGGSLLSLILTIagvlflvlgllaLLFLLLAREKA 298
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 389 KMEEQCRDLNKRLEKETVQSKDFKLEVDKLSVRITALEKLEDALDKSKQECYSLKCNLEK--EKMTTKQLSEELESL--N 464
Cdd:COG4717 299 SLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEEleEELQLEELEQEIAALlaE 378
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 465 ARIKELEAIESRLEKTEiTLKDDLTKLKTLTVMLVDERKTMSEKLKQT-----EDKLQSTTSQLQAEQNKVTTVTEKL-- 537
Cdd:COG4717 379 AGVEDEEELRAALEQAE-EYQELKEELEELEEQLEELLGELEELLEALdeeelEEELEELEEELEELEEELEELREELae 457
|
410 420 430
....*....|....*....|....*....|....*...
gi 295424207 538 IEETKRALKSKTDAEEKMYsvtkERDDLRNKLKAEEEK 575
Cdd:COG4717 458 LEAELEQLEEDGELAELLQ----ELEELKAELRELAEE 491
|
|
| rad50 |
TIGR00606 |
rad50; All proteins in this family for which functions are known are involvedin recombination, ... |
135-721 |
3.93e-07 |
|
rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).
Pssm-ID: 129694 [Multi-domain] Cd Length: 1311 Bit Score: 54.67 E-value: 3.93e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 135 EKPMNELDKVVE-KHKESHRRILEQLLMVERSHRQTIMEMEEEKRKHKEYMKKSDEFINLLEQECERLKKLIDQETASQE 213
Cdd:TIGR00606 278 KKQMEKDNSELElKMEKVFQGTDEQLNDLYHNHQRTVREKERELVDCQRELEKLNKERRLLNQEKTELLVEQGRLQLQAD 357
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 214 KKEQEKEKRIKTLKEELTKLKSFAL---MVVDEQQRLTAQLALQRQKIQALTTSA--KETQGKLALAEARAQEEEQKATR 288
Cdd:TIGR00606 358 RHQEHIRARDSLIQSLATRLELDGFergPFSERQIKNFHTLVIERQEDEAKTAAQlcADLQSKERLKQEQADEIRDEKKG 437
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 289 LEKELQTQTTefhqnqdkimaKLTNEDSQNRQLRQKLAALSRQIDELEETNRSLRKAEEEL------QDIKDKINKGEYG 362
Cdd:TIGR00606 438 LGRTIELKKE-----------ILEKKQEELKFVIKELQQLEGSSDRILELDQELRKAERELskaeknSLTETLKKEVKSL 506
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 363 NSGIMDEVDELRKRVLDMEGKDEE---LIKME----------EQCRDLNKRLEKE-TVQSKDF---KLEVDKLSVRITAL 425
Cdd:TIGR00606 507 QNEKADLDRKLRKLDQEMEQLNHHtttRTQMEmltkdkmdkdEQIRKIKSRHSDElTSLLGYFpnkKQLEDWLHSKSKEI 586
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 426 EKLEDALDKSKQECYSLKCNLEKEKMTTKQLSEELESLNARIKEL---EAIESRLEKteitLKDDLTKLKTLTVMLVDER 502
Cdd:TIGR00606 587 NQTRDRLAKLNKELASLEQNKNHINNELESKEEQLSSYEDKLFDVcgsQDEESDLER----LKEEIEKSSKQRAMLAGAT 662
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 503 KTMSEKLKQTEDKLQSTTSQLQAEQNkvttvTEKLIEETKRALKSKTdaeekmYSVTKERDDLRNKLKAEEEKGHDLLSK 582
Cdd:TIGR00606 663 AVYSQFITQLTDENQSCCPVCQRVFQ-----TEAELQEFISDLQSKL------RLAPDKLKSTESELKKKEKRRDEMLGL 731
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 583 VTILKNRLQSLEAIEKDFVK--NKLNQDSSKSTAALHQENNKIKELSQEVENLKLKLKDMKAIEDDLMKTEDeyetLERR 660
Cdd:TIGR00606 732 APGRQSIIDLKEKEIPELRNklQKVNRDIQRLKNDIEEQETLLGTIMPEEESAKVCLTDVTIMERFQMELKD----VERK 807
|
570 580 590 600 610 620
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 295424207 661 YANERDKAQFLSQELEHAKMELAKYKLAEK--TESSHEQWLFRRLQEEEAKSGHLSREVDALK 721
Cdd:TIGR00606 808 IAQQAAKLQGSDLDRTVQQVNQEKQEKQHEldTVVSKIELNRKLIQDQQEQIQHLKSKTNELK 870
|
|
| sbcc |
TIGR00618 |
exonuclease SbcC; All proteins in this family for which functions are known are part of an ... |
123-765 |
5.62e-07 |
|
exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 54.20 E-value: 5.62e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 123 QAKSAPWQEDIYEKPMNELDKVVEKHKESHRRILEQL-LMVERSHRQTimEMEEEKRKHKEYMKKSDEFINL---LEQEC 198
Cdd:TIGR00618 213 MPDTYHERKQVLEKELKHLREALQQTQQSHAYLTQKReAQEEQLKKQQ--LLKQLRARIEELRAQEAVLEETqerINRAR 290
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 199 ERLKKLIDQE-TASQEKKEQEKEKRIKTLKEELTKLKSFALMVVDEQQRLTAQLALQRQKIQALTTSAKET-QGKLALAE 276
Cdd:TIGR00618 291 KAAPLAAHIKaVTQIEQQAQRIHTELQSKMRSRAKLLMKRAAHVKQQSSIEEQRRLLQTLHSQEIHIRDAHeVATSIREI 370
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 277 ARAQEEEQKATRLEKELQTQTTEFHQNQDKIMAKLTNE-------DSQNRQLRQKLAALSRQIDELEETNRSLRKA-EEE 348
Cdd:TIGR00618 371 SCQQHTLTQHIHTLQQQKTTLTQKLQSLCKELDILQREqatidtrTSAFRDLQGQLAHAKKQQELQQRYAELCAAAiTCT 450
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 349 LQDIKDKI---NKGEYGnsgiMDEVDELRKRVLDMEGKDEELIKMEEQCRDLNKRLEKETVQS-------KDFKLEVDKL 418
Cdd:TIGR00618 451 AQCEKLEKihlQESAQS----LKEREQQLQTKEQIHLQETRKKAVVLARLLELQEEPCPLCGScihpnpaRQDIDNPGPL 526
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 419 SVRITALE----KLEDALDKSKQECYSLKCNLEKEKMTTKQLSEELESLNARIKELEAIESRLEKTEITLKDDLTKLKTL 494
Cdd:TIGR00618 527 TRRMQRGEqtyaQLETSEEDVYHQLTSERKQRASLKEQMQEIQQSFSILTQCDNRSKEDIPNLQNITVRLQDLTEKLSEA 606
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 495 TVMLVDERKTMSEKLKQTEDKLQSTTSQLQAEQN---KVTTVTEKLI-----EETKRALKSKTDAEEKMYSVTKERDDLR 566
Cdd:TIGR00618 607 EDMLACEQHALLRKLQPEQDLQDVRLHLQQCSQElalKLTALHALQLtltqeRVREHALSIRVLPKELLASRQLALQKMQ 686
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 567 NKLKAEEEKGHDLLSKVTILKNRLQSLEAIEKDFvkNKLNQDSSKSTAALHQENNKIKELSQEVENLK------LKLKDM 640
Cdd:TIGR00618 687 SEKEQLTYWKEMLAQCQTLLRELETHIEEYDREF--NEIENASSSLGSDLAAREDALNQSLKELMHQArtvlkaRTEAHF 764
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 641 KAIEDDLM--KTEDEYETLERRYANERDKAQFLSQELehakmelakyklaEKTESSHEQWLFRRLQEEEAKSGHLSREVD 718
Cdd:TIGR00618 765 NNNEEVTAalQTGAELSHLAAEIQFFNRLREEDTHLL-------------KTLEAEIGQEIPSDEDILNLQCETLVQEEE 831
|
650 660 670 680
....*....|....*....|....*....|....*....|....*..
gi 295424207 719 ALKEKIHEYMATEDLICHLQGDHSLLQKKLNQQENRNRDLGREIENL 765
Cdd:TIGR00618 832 QFLSRLEEKSATLGEITHQLLKYEECSKQLAQLTQEQAKIIQLSDKL 878
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
346-771 |
7.30e-07 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 53.23 E-value: 7.30e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 346 EEELQDIKDKINKGEYGNSGI-MDEVDELRKRVLDMEGKDEELIKMEEQCRDLNKRLEketvqskDFKLEVDKLSVRITA 424
Cdd:COG4717 48 LERLEKEADELFKPQGRKPELnLKELKELEEELKEAEEKEEEYAELQEELEELEEELE-------ELEAELEELREELEK 120
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 425 LEKLEDALDKSKQecyslkcnLEKEKMTTKQLSEELESLNARIKELEAIESRLEKteitLKDDLTKLKTltvmlvDERKT 504
Cdd:COG4717 121 LEKLLQLLPLYQE--------LEALEAELAELPERLEELEERLEELRELEEELEE----LEAELAELQE------ELEEL 182
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 505 MSEKLKQTEDKLQSTTSQLQAEQNKVTTVTEKLieETKRALKSKTDAEEKMYSVTKERDDLRNKLKAEEE---------- 574
Cdd:COG4717 183 LEQLSLATEEELQDLAEELEELQQRLAELEEEL--EEAQEELEELEEELEQLENELEAAALEERLKEARLllliaaalla 260
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 575 ---KGHDLLSKVTILKNRLQSLEAI------EKDFVKNKLNQDSSKSTAALHQENNKIKELSQEVENLKLKLKDMKAIED 645
Cdd:COG4717 261 llgLGGSLLSLILTIAGVLFLVLGLlallflLLAREKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELL 340
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 646 DLMKTEDEYETLERRYANERDKAQFlsQELEHAKMELAKYKLAEkTESSHEQWL--FRRLQEEEAKSGHLSREVDALKEK 723
Cdd:COG4717 341 ELLDRIEELQELLREAEELEEELQL--EELEQEIAALLAEAGVE-DEEELRAALeqAEEYQELKEELEELEEQLEELLGE 417
|
410 420 430 440
....*....|....*....|....*....|....*....|....*...
gi 295424207 724 IHEYMATEDLichlqgdhSLLQKKLNQQENRNRDLGREIENLTKELER 771
Cdd:COG4717 418 LEELLEALDE--------EELEEELEELEEELEELEEELEELREELAE 457
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
454-670 |
7.68e-07 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 52.84 E-value: 7.68e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 454 KQLSEELESLNARIKELEAIESRLEKTEITLKDDLTKLKTLTVMLVDERKTMSEKLKQTEDKLQSTTSQLQAEQNKVTTV 533
Cdd:COG4942 23 AEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQ 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 534 TEKLIEETKRALK--------------SKTDAEEKMY---SVTKERDDLRNKLKAEEEKGHDLLSKVTILKNRLQSLEAi 596
Cdd:COG4942 103 KEELAELLRALYRlgrqpplalllspeDFLDAVRRLQylkYLAPARREQAEELRADLAELAALRAELEAERAELEALLA- 181
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 295424207 597 EKDFVKNKLNQDSSKSTAALHQENNKIKELSQEVENLKLKLKDMKAIEDDLMKTEDEYETLERRYANERDKAQF 670
Cdd:COG4942 182 ELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPAAGFAALKGKL 255
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
153-771 |
1.19e-06 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 53.00 E-value: 1.19e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 153 RRILEQLlmveRSHRQTIMEMEEEKRKHKEYMKKSD-----EFINLLEQECERLKKLIDQETAsqekKEQEKEKRIKTLK 227
Cdd:COG4913 251 IELLEPI----RELAERYAAARERLAELEYLRAALRlwfaqRRLELLEAELEELRAELARLEA----ELERLEARLDALR 322
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 228 EELTKLKSfALMVVDEQQ--RLTAQLALQRQKIQALTTSAKETQGKLALAEARAQEEEQKATRLEKELQTQTTEFHQNQD 305
Cdd:COG4913 323 EELDELEA-QIRGNGGDRleQLEREIERLERELEERERRRARLEALLAALGLPLPASAEEFAALRAEAAALLEALEEELE 401
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 306 KIMAKLTNEDSQNRQLRQKLAALSRQIDELEETNRSLrkaEEELQDIKDKINKgeygNSGImDEVD-----ELrkrvLDM 380
Cdd:COG4913 402 ALEEALAEAEAALRDLRRELRELEAEIASLERRKSNI---PARLLALRDALAE----ALGL-DEAElpfvgEL----IEV 469
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 381 EGKDEE---------------LIKMEEQCRDLNKRLEketvqSKDFKLEVDKLSVRITALEKLEDALDKSkqecySLkcn 445
Cdd:COG4913 470 RPEEERwrgaiervlggfaltLLVPPEHYAAALRWVN-----RLHLRGRLVYERVRTGLPDPERPRLDPD-----SL--- 536
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 446 leKEKMTTKQ--LSEELESLNARIKELEAIES----RLEKTEITL------------KDDLTKLKTLTVMLVDER---KT 504
Cdd:COG4913 537 --AGKLDFKPhpFRAWLEAELGRRFDYVCVDSpeelRRHPRAITRagqvkgngtrheKDDRRRIRSRYVLGFDNRaklAA 614
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 505 MSEKLKQTEDKLQSTTSQLQAEQNKVTTVTEKLieETKRALKSKTDAEEKMYSVTKERDDLRNKLkAEEEKGHDLLSKvt 584
Cdd:COG4913 615 LEAELAELEEELAEAEERLEALEAELDALQERR--EALQRLAEYSWDEIDVASAEREIAELEAEL-ERLDASSDDLAA-- 689
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 585 iLKNRLQSLEAIEKDFVKnklnqdsskstaALHQENNKIKELSQEVENLKLKLKDMKAIEDDL--MKTEDEYETLERRYA 662
Cdd:COG4913 690 -LEEQLEELEAELEELEE------------ELDELKGEIGRLEKELEQAEEELDELQDRLEAAedLARLELRALLEERFA 756
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 663 N------ERDKAQFLSQELEHAKMELAkyKLAEKTESSHEQwlFRRLQEEEAksGHLSREVDALKE--KIHEYMATEDLI 734
Cdd:COG4913 757 AalgdavERELRENLEERIDALRARLN--RAEEELERAMRA--FNREWPAET--ADLDADLESLPEylALLDRLEEDGLP 830
|
650 660 670
....*....|....*....|....*....|....*..
gi 295424207 735 CHlqgdhsllQKKLNQQENRNrdLGREIENLTKELER 771
Cdd:COG4913 831 EY--------EERFKELLNEN--SIEFVADLLSKLRR 857
|
|
| SMC_N |
pfam02463 |
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
139-770 |
1.59e-06 |
|
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 52.67 E-value: 1.59e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 139 NELDKVVEKHKESHRRILEQLLMVERSHRQTIMEMEEEKRkHKEYMKKSDEFINLLEQECERLKKLIDQETASqekkeqe 218
Cdd:pfam02463 195 LKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKL-NEERIDLLQELLRDEQEEIESSKQEIEKEEEK------- 266
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 219 kEKRIKTLKEELTKLKSFALMVVDEQQRLTAQLALQRQKIQALTTSA----KETQGKLALAEARAQEEEQKATRLEKELQ 294
Cdd:pfam02463 267 -LAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDeeklKESEKEKKKAEKELKKEKEEIEELEKELK 345
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 295 TQTTEFHQNQDKIMAKLTNEDSQNRQLRQKLAALSRQIDELEETNRSLRKAEEELQDIKDKINKGEYGNSGIMDEVDELR 374
Cdd:pfam02463 346 ELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEKEAQLLLELARQLEDLLKEEK 425
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 375 KRVLDMEGKDEELIkmEEQCRDLNKRLEKETVQSKDFKLEVDKLSVRITALEKLEDALDKSKQECYSLKCNLEKEKMTTK 454
Cdd:pfam02463 426 KEELEILEEEEESI--ELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQEQLELLLSRQKLEERSQKES 503
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 455 QLSEELESLNARIKELEAIesRLEKTEITLKDDLTKLKTLTVMLVDERKTMSEKLKQTEDklqsttsqlqAEQNKVTTVT 534
Cdd:pfam02463 504 KARSGLKVLLALIKDGVGG--RIISAHGRLGDLGVAVENYKVAISTAVIVEVSATADEVE----------ERQKLVRALT 571
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 535 EKLIEETKRALKSKTDAEEKMYSVTKERDDLRNKLKAEE-EKGHDLLSKVTILKNRLQSLEAIEKDFVKNKLNQDSSKST 613
Cdd:pfam02463 572 ELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKaTLEADEDDKRAKVVEGILKDTELTKLKESAKAKESGLRKG 651
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 614 AALHQENNKIKELSQEVENLKLKLkdmKAIEDDLMKTEDEYETLERRYANERDKAQFLSQELEHAKMELAKYKLAEKtes 693
Cdd:pfam02463 652 VSLEEGLAEKSEVKASLSELTKEL---LEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLAD--- 725
|
570 580 590 600 610 620 630
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 295424207 694 sheqwlfrRLQEEEAKSghlSREVDALKEKIHEYMATEDLICHLQGDHSLLQKKLNQQENRNRDLGREIENLTKELE 770
Cdd:pfam02463 726 --------RVQEAQDKI---NEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEE 791
|
|
| Myosin_tail_1 |
pfam01576 |
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ... |
254-569 |
3.03e-06 |
|
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.
Pssm-ID: 460256 [Multi-domain] Cd Length: 1081 Bit Score: 51.71 E-value: 3.03e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 254 QRQKIQALTtSAKETQGKLALAEAR---AQEEEQKATRLEKELQTQTTEFHQNQDKIMAKLTNEDSQNRQLRQKLAALSR 330
Cdd:pfam01576 762 RKQRAQAVA-AKKKLELDLKELEAQidaANKGREEAVKQLKKLQAQMKDLQRELEEARASRDEILAQSKESEKKLKNLEA 840
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 331 QIDELEE----TNRSLRKAEEELQDIKDKINKGEYGNSGIMDEVDELRKRVLDMEgkdEELIKMEEQCRDLNKRLEKETV 406
Cdd:pfam01576 841 ELLQLQEdlaaSERARRQAQQERDELADEIASGASGKSALQDEKRRLEARIAQLE---EELEEEQSNTELLNDRLRKSTL 917
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 407 QSKDFKLEvdkLSVRITALEKLEDALDKSKQECYSLKCNLE--------KEKMTTKQLSEEL----ESLNARIKELEAIE 474
Cdd:pfam01576 918 QVEQLTTE---LAAERSTSQKSESARQQLERQNKELKAKLQemegtvksKFKSSIAALEAKIaqleEQLEQESRERQAAN 994
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 475 SRLEKTEITLKDdltklktlTVMLVDERKTMSEKLKQTEDKLQSTTSQLQAEQNKVTTVTEKLIEETKRALKSKTDAEEK 554
Cdd:pfam01576 995 KLVRRTEKKLKE--------VLLQVEDERRHADQYKDQAEKGNSRMKQLKRQLEEAEEEASRANAARRKLQRELDDATES 1066
|
330
....*....|....*
gi 295424207 555 MYSVTKERDDLRNKL 569
Cdd:pfam01576 1067 NESMNREVSTLKSKL 1081
|
|
| MAD |
pfam05557 |
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint ... |
277-783 |
3.79e-06 |
|
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint (Mitotic arrest deficient or MAD) proteins. The mitotic spindle checkpoint monitors proper attachment of the bipolar spindle to the kinetochores of aligned sister chromatids and causes a cell cycle arrest in prometaphase when failures occur. Multiple components of the mitotic spindle checkpoint have been identified in yeast and higher eukaryotes. In S.cerevisiae, the existence of a Mad1-dependent complex containing Mad2, Mad3, Bub3 and Cdc20 has been demonstrated.
Pssm-ID: 461677 [Multi-domain] Cd Length: 660 Bit Score: 51.28 E-value: 3.79e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 277 ARAQEEEQKATRLEKELQTQTTEFHQNQDKIMAKLTNEDSQNRQLRQKLAALSRQIDELEETNRSLRKAEEELQDIKDKI 356
Cdd:pfam05557 48 DRNQELQKRIRLLEKREAEAEEALREQAELNRLKKKYLEALNKKLNEKESQLADAREVISCLKNELSELRRQIQRAELEL 127
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 357 NKGEYGNSGIMDEVDELRKRVLDMEGKDEELIKMEEQCRDLNKR---LEKETVQSKDFKLEVDKLSVRITALEKLEDALD 433
Cdd:pfam05557 128 QSTNSELEELQERLDLLKAKASEAEQLRQNLEKQQSSLAEAEQRikeLEFEIQSQEQDSEIVKNSKSELARIPELEKELE 207
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 434 KSKQECYSLKCNLEKEKMttkqLSEELESLNARIKELEAIESRLEKTEITLKDDLTKLKTLTVMLVDERKTMseklkQTE 513
Cdd:pfam05557 208 RLREHNKHLNENIENKLL----LKEEVEDLKRKLEREEKYREEAATLELEKEKLEQELQSWVKLAQDTGLNL-----RSP 278
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 514 DKLQSTTSQLQAEQNKVTTVTEKLIEETKRALKSKTDAEEKMYSVTKERDDLRNKLKAEEEKGHDLLSKVTILKNRLQSL 593
Cdd:pfam05557 279 EDLSRRIEQLQQREIVLKEENSSLTSSARQLEKARRELEQELAQYLKKIEDLNKKLKRHKALVRRLQRRVLLLTKERDGY 358
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 594 EAIEKDFVKNKLNQDSSKstaalhQENNKIKELSQEVENLKLKLKDMKAieddlmktedEYETLERRYANERDKAQFLSQ 673
Cdd:pfam05557 359 RAILESYDKELTMSNYSP------QLLERIEEAEDMTQKMQAHNEEMEA----------QLSVAEEELGGYKQQAQTLER 422
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 674 ELEhakmelakyklaektessheqwlFRRLQEEEAKSGHLSREVDALKEKIHEYMAT-----------EDLICH--LQGD 740
Cdd:pfam05557 423 ELQ-----------------------ALRQQESLADPSYSKEEVDSLRRKLETLELErqrlreqknelEMELERrcLQGD 479
|
490 500 510 520
....*....|....*....|....*....|....*....|....*...
gi 295424207 741 HSL-----LQKKLNQQENRNRDLGREIENLTKELERYRHFSKSLRPSL 783
Cdd:pfam05557 480 YDPkktkvLHLSMNPAAEAYQQRKNQLEKLQAEIERLKRLLKKLEDDL 527
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
126-341 |
4.30e-06 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 50.53 E-value: 4.30e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 126 SAPWQEDIYEKPMNELDKVvEKHKESHRRILEQLLMVERSHRQTIMEMEEEKRKHKEYMKKSDEFINLLEQECERLKKLI 205
Cdd:COG4942 14 AAAAQADAAAEAEAELEQL-QQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEI 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 206 DQETASQEKKEQEKEKRIKTL---------------KEELTKLKSFALM--VVDEQQRLTAQLALQRQKIQALTTSAKET 268
Cdd:COG4942 93 AELRAELEAQKEELAELLRALyrlgrqpplalllspEDFLDAVRRLQYLkyLAPARREQAEELRADLAELAALRAELEAE 172
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 295424207 269 QGKLALAEARAQEEEQKATRLEKELQTQTTEFHQNQDKIMAKLTNEDSQNRQLRQKLAALSRQIDELEETNRS 341
Cdd:COG4942 173 RAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPA 245
|
|
| rad50 |
TIGR00606 |
rad50; All proteins in this family for which functions are known are involvedin recombination, ... |
91-709 |
5.41e-06 |
|
rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).
Pssm-ID: 129694 [Multi-domain] Cd Length: 1311 Bit Score: 50.82 E-value: 5.41e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 91 LRAEKIDLALLEAQYGFVTPKKVLEALQRDafqaksapwQEDIYEKPMNELDKVVEKHKesHRRILEQLLMVERShrqti 170
Cdd:TIGR00606 480 LRKAERELSKAEKNSLTETLKKEVKSLQNE---------KADLDRKLRKLDQEMEQLNH--HTTTRTQMEMLTKD----- 543
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 171 mEMEEEKRKHKEYMKKSDEFINLLEQECErlKKLIDQETASQEKKEQEKEKRIKTLKEELTKLKSFALMVVDEQQRLTAQ 250
Cdd:TIGR00606 544 -KMDKDEQIRKIKSRHSDELTSLLGYFPN--KKQLEDWLHSKSKEINQTRDRLAKLNKELASLEQNKNHINNELESKEEQ 620
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 251 LALQRQKIQALTTSAKETQGKLALAEARAQEEEQKA-----TRLEKELQTQTTEFHQNQDKIMAKLTNEDSQNRQLRQKL 325
Cdd:TIGR00606 621 LSSYEDKLFDVCGSQDEESDLERLKEEIEKSSKQRAmlagaTAVYSQFITQLTDENQSCCPVCQRVFQTEAELQEFISDL 700
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 326 AALSRQI-DELEETNRSLRKAEEELQDIKDKINKGEYGNSGIMDEVDELRKRV----LDMEGKDEELIKMEEQCRDLNKR 400
Cdd:TIGR00606 701 QSKLRLApDKLKSTESELKKKEKRRDEMLGLAPGRQSIIDLKEKEIPELRNKLqkvnRDIQRLKNDIEEQETLLGTIMPE 780
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 401 LEKETVQSKD------FKLEVDKLSVRITALEKLEDA--LDKSKQECYSLKCNLEKEKMTTKQLSEELESL----NARIK 468
Cdd:TIGR00606 781 EESAKVCLTDvtimerFQMELKDVERKIAQQAAKLQGsdLDRTVQQVNQEKQEKQHELDTVVSKIELNRKLiqdqQEQIQ 860
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 469 ELEAIESRLEKTEITLKDDLTKLKTL---TVMLVDERKTMSEKLKQTEDKLQSTTSQLQAEQNKVTTVTEKLIEETKRAL 545
Cdd:TIGR00606 861 HLKSKTNELKSEKLQIGTNLQRRQQFeeqLVELSTEVQSLIREIKDAKEQDSPLETFLEKDQQEKEELISSKETSNKKAQ 940
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 546 KSKTDAEEKMYSVTKERDDLRNKLKAEEE-----KGHDLLSKVTILKNRLQSLEAIEKDFVKNKLNQDSSKSTAALHQEN 620
Cdd:TIGR00606 941 DKVNDIKEKVKNIHGYMKDIENKIQDGKDdylkqKETELNTVNAQLEECEKHQEKINEDMRLMRQDIDTQKIQERWLQDN 1020
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 621 -------NKIKELSQEVENLKLKLKDMKAIE--DDLMKTEDEYETLERRYANERDKAQFLSQELEHAKMELAKYKLAEKT 691
Cdd:TIGR00606 1021 ltlrkreNELKEVEEELKQHLKEMGQMQVLQmkQEHQKLEENIDLIKRNHVLALGRQKGYEKEIKHFKKELREPQFRDAE 1100
|
650
....*....|....*...
gi 295424207 692 ESSHEQWLFRRLQEEEAK 709
Cdd:TIGR00606 1101 EKYREMMIVMRTTELVNK 1118
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
223-796 |
6.84e-06 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 50.40 E-value: 6.84e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 223 IKTLKEELTKLKSFALMVVDEQQRLTAQLALQRQKIQALTTSAKETQGKLALAEARAQEEEQKATRLEKELQTQTT---- 298
Cdd:TIGR04523 126 LNKLEKQKKENKKNIDKFLTEIKKKEKELEKLNNKYNDLKKQKEELENELNLLEKEKLNIQKNIDKIKNKLLKLELllsn 205
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 299 --EFHQNQDKIMAKLTNEDSQNRQLRQKLAALSrqiDELEETNRSLRKAEEELQDIKDKINKgeygnsgimdEVDELRKR 376
Cdd:TIGR04523 206 lkKKIQKNKSLESQISELKKQNNQLKDNIEKKQ---QEINEKTTEISNTQTQLNQLKDEQNK----------IKKQLSEK 272
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 377 VLDMEGKDEELIKMEEQCRDLNKRL-----EKETVQSKDFKLEVDKLSVRItalEKLEDALDKSKQECYSLKCNLEKEKM 451
Cdd:TIGR04523 273 QKELEQNNKKIKELEKQLNQLKSEIsdlnnQKEQDWNKELKSELKNQEKKL---EEIQNQISQNNKIISQLNEQISQLKK 349
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 452 TTKQLSEELESLNARIKELEAIESRLEKTEITLKDDLTKLKTLTVMLvderKTMSEKLKQTEDKLQSTTSQLQAEQNKVT 531
Cdd:TIGR04523 350 ELTNSESENSEKQRELEEKQNEIEKLKKENQSYKQEIKNLESQINDL----ESKIQNQEKLNQQKDEQIKKLQQEKELLE 425
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 532 TVTEKLIEETKRALKSKTDAEEKMYSVTKERDDLRNKLKAEEEKGHDLLSKVTILKnrlQSLEAIEKDFVKNklnqdssk 611
Cdd:TIGR04523 426 KEIERLKETIIKNNSEIKDLTNQDSVKELIIKNLDNTRESLETQLKVLSRSINKIK---QNLEQKQKELKSK-------- 494
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 612 sTAALHQENNKIKELSQEVENLKLKLKDMKAIEDDLmktEDEYETLERRYANERDKAQFLSQELEHAKMELAKYKLAEKT 691
Cdd:TIGR04523 495 -EKELKKLNEEKKELEEKVKDLTKKISSLKEKIEKL---ESEKKEKESKISDLEDELNKDDFELKKENLEKEIDEKNKEI 570
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 692 ESSHEQW--LFRRLQEEEAKSGHLSREVDALKEKIHEYMATEdlichlqgdhSLLQKKLNQQENRNRDLGREIENLTKEL 769
Cdd:TIGR04523 571 EELKQTQksLKKKQEEKQELIDQKEKEKKDLIKEIEEKEKKI----------SSLEKELEKAKKENEKLSSIIKNIKSKK 640
|
570 580
....*....|....*....|....*..
gi 295424207 770 ERYRHFSKSLRPSLNERRISDPQVFSK 796
Cdd:TIGR04523 641 NKLKQEVKQIKETIKEIRNKWPEIIKK 667
|
|
| CCDC158 |
pfam15921 |
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ... |
156-702 |
1.10e-05 |
|
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.
Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 49.73 E-value: 1.10e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 156 LEQLLMVERSHRQTIMEMEEEKRKHK-EYMKKSDEFINLLEQECERLKKLIDQETASQEKKEQEKEKrIKTLKEELTKLK 234
Cdd:pfam15921 431 LEALLKAMKSECQGQMERQMAAIQGKnESLEKVSSLTAQLESTKEMLRKVVEELTAKKMTLESSERT-VSDLTASLQEKE 509
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 235 SFALMVVDEQQRLTAQLALQRQKIQALTTSAKETqgklalaeaRAQEEEQKATRLEKELQTQTTEFHQNQDKIMAKLTNE 314
Cdd:pfam15921 510 RAIEATNAEITKLRSRVDLKLQELQHLKNEGDHL---------RNVQTECEALKLQMAEKDKVIEILRQQIENMTQLVGQ 580
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 315 DSQNRQLRQ-KLAALSRQID----ELEETNRSLRKAEEELQDIKDKINKGEYGNSGIMDEVDELRKRVLDMEGKDEELIK 389
Cdd:pfam15921 581 HGRTAGAMQvEKAQLEKEINdrrlELQEFKILKDKKDAKIRELEARVSDLELEKVKLVNAGSERLRAVKDIKQERDQLLN 660
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 390 MEEQCR-DLNKRLEKETVQSKDFKlevdklsvritalekledalDKSKQecysLKCNLEKEKMTTKQLSEELESLNARIK 468
Cdd:pfam15921 661 EVKTSRnELNSLSEDYEVLKRNFR--------------------NKSEE----METTTNKLKMQLKSAQSELEQTRNTLK 716
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 469 ELEAIESRLEKTEITLKDDLTKLK------TLTVMLVDERKTMSEK----LKQTEDKLQSTTSQLQAEQNKVTTVTEKLI 538
Cdd:pfam15921 717 SMEGSDGHAMKVAMGMQKQITAKRgqidalQSKIQFLEEAMTNANKekhfLKEEKNKLSQELSTVATEKNKMAGELEVLR 796
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 539 EETKRALKSKTDAEEKMYSVTKERDDLRNKLKAEEEKGHDLLSKVTILKNRLQSLEAIEKDFVKNKL-----------NQ 607
Cdd:pfam15921 797 SQERRLKEKVANMEVALDKASLQFAECQDIIQRQEQESVRLKLQHTLDVKELQGPGYTSNSSMKPRLlqpasftrthsNV 876
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 608 DSSKSTAA-LHQENNKIKELSQE-VENLKLKLKDMKAI-----EDDLMKTEDEYETLERRYANERDKAQFLSQELEHAKM 680
Cdd:pfam15921 877 PSSQSTASfLSHHSRKTNALKEDpTRDLKQLLQELRSVineepTVQLSKAEDKGRAPSLGALDDRVRDCIIESSLRSDIC 956
|
570 580
....*....|....*....|..
gi 295424207 681 ELAKYKLaeKTESSHEQWLFRR 702
Cdd:pfam15921 957 HSSSNSL--QTEGSKSSETCSR 976
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
74-471 |
1.19e-05 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 49.38 E-value: 1.19e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 74 LSILEGELQARDEVIGILRAEKIDLALLEAQYGFVTPKKVLEA-LQRDAFQAKSAPWQEDIYEKPMNELDKVVEKHKESH 152
Cdd:COG4717 97 LEELEEELEELEAELEELREELEKLEKLLQLLPLYQELEALEAeLAELPERLEELEERLEELRELEEELEELEAELAELQ 176
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 153 RRILEQLLMVERSHRQTIMEMEEEKRKHKEYMKKSDEFINLLEQECERLKKLIDQETASQEKKEQEkekriKTLKEELTK 232
Cdd:COG4717 177 EELEELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQEELEELEEELEQLENELEAAALE-----ERLKEARLL 251
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 233 LKSFALMVVdeqqrLTAQLALQRQKIQALTTSAKETQGKLALAEARAQEEEQKATRLEKELQTQTTEFHQNQDKIMAKLT 312
Cdd:COG4717 252 LLIAAALLA-----LLGLGGSLLSLILTIAGVLFLVLGLLALLFLLLAREKASLGKEAEELQALPALEELEEEELEELLA 326
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 313 NEDSQNRQLRQKLAALSRQIDELEETNRSLRKAEEELQDIKDKINKGEYGNSGIMDEVDELRKRVldmeGKDEELIKMEE 392
Cdd:COG4717 327 ALGLPPDLSPEELLELLDRIEELQELLREAEELEEELQLEELEQEIAALLAEAGVEDEEELRAAL----EQAEEYQELKE 402
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 295424207 393 QCRDLNKRLEKETVQSKDFKLEVDKLSVRiTALEKLEDALDKSKQECyslkcnlekekmttKQLSEELESLNARIKELE 471
Cdd:COG4717 403 ELEELEEQLEELLGELEELLEALDEEELE-EELEELEEELEELEEEL--------------EELREELAELEAELEQLE 466
|
|
| 46 |
PHA02562 |
endonuclease subunit; Provisional |
130-355 |
1.43e-05 |
|
endonuclease subunit; Provisional
Pssm-ID: 222878 [Multi-domain] Cd Length: 562 Bit Score: 49.24 E-value: 1.43e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 130 QEDIYEKPMNELDKVVEKHKESHRRILEQLLMVERSHRQTIMEMEEEKRKHKEYMKKSDEFINLLEQECERLKKLIDQet 209
Cdd:PHA02562 196 QIKTYNKNIEEQRKKNGENIARKQNKYDELVEEAKTIKAEIEELTDELLNLVMDIEDPSAALNKLNTAAAKIKSKIEQ-- 273
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 210 asqekkeqekekriktlkeeLTKLKSFaLMVVDEQQRLTAQLALQRQKIQALTTSAKETQGKLALAEARAQEEEQKatrl 289
Cdd:PHA02562 274 --------------------FQKVIKM-YEKGGVCPTCTQQISEGPDRITKIKDKLKELQHSLEKLDTAIDELEEI---- 328
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 295424207 290 EKELQTQTTEFHQNQDKIMAK---LTNEDSQNRQLRqklAALSRQIDELEETNRSLRKAEEELQDIKDK 355
Cdd:PHA02562 329 MDEFNEQSKKLLELKNKISTNkqsLITLVDKAKKVK---AAIEELQAEFVDNAEELAKLQDELDKIVKT 394
|
|
| EzrA |
pfam06160 |
Septation ring formation regulator, EzrA; During the bacterial cell cycle, the tubulin-like ... |
280-785 |
1.64e-05 |
|
Septation ring formation regulator, EzrA; During the bacterial cell cycle, the tubulin-like cell-division protein FtsZ polymerizes into a ring structure that establishes the location of the nascent division site. EzrA modulates the frequency and position of FtsZ ring formation. The structure contains 5 spectrin like alpha helical repeats.
Pssm-ID: 428797 [Multi-domain] Cd Length: 542 Bit Score: 48.70 E-value: 1.64e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 280 QEEEQKATRLEKELQTQTT--EFHQNQDKIMAKltnedsqnrqlrqKLAALSRQIDELEETNRSLR--KAEEELQDIKDK 355
Cdd:pfam06160 28 QEELSKVKKLNLTGETQEKfeEWRKKWDDIVTK-------------SLPDIEELLFEAEELNDKYRfkKAKKALDEIEEL 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 356 INKGEygnsgimDEVDELRKRVLDMEGKDEELIKMEEQCRDLNKRLeKETVQSKDFKLEvdklsvriTALEKLEDALDK- 434
Cdd:pfam06160 95 LDDIE-------EDIKQILEELDELLESEEKNREEVEELKDKYREL-RKTLLANRFSYG--------PAIDELEKQLAEi 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 435 ----SKQECYSLKCNLEKEKMTTKQLSEELESLNARIkelEAIESRLEKTEITLKDDLTKLK-TLTVMLVD----ERKTM 505
Cdd:pfam06160 159 eeefSQFEELTESGDYLEAREVLEKLEEETDALEELM---EDIPPLYEELKTELPDQLEELKeGYREMEEEgyalEHLNV 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 506 SEKLKQTEDKLQSTTSQLqaEQNKVTTVtEKLIEETKRALKSKTDAEEKMY----SVTKERDDLRNKLKAEEEKGHDLLS 581
Cdd:pfam06160 236 DKEIQQLEEQLEENLALL--ENLELDEA-EEALEEIEERIDQLYDLLEKEVdakkYVEKNLPEIEDYLEHAEEQNKELKE 312
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 582 KVTILK-------NRLQSLEAIEKDFvkNKLNQDSSKSTAALHqenNKIKELSQEVENLKLKLKDMKAIEDDLMKTEDEY 654
Cdd:pfam06160 313 ELERVQqsytlneNELERVRGLEKQL--EELEKRYDEIVERLE---EKEVAYSELQEELEEILEQLEEIEEEQEEFKESL 387
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 655 ETLERRYANERDKAQFLSQELEHAKMELAKYKL--------AEKTESSHE-QWLFRRLQEEEAKSGHLSREVDALKEKIH 725
Cdd:pfam06160 388 QSLRKDELEAREKLDEFKLELREIKRLVEKSNLpglpesylDYFFDVSDEiEDLADELNEVPLNMDEVNRLLDEAQDDVD 467
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 295424207 726 E-YMATEDLIchlqgDHSLLQKKLNQQENRnrdlgreienltkelerYRHFSKSLRPSLNE 785
Cdd:pfam06160 468 TlYEKTEELI-----DNATLAEQLIQYANR-----------------YRSSNPEVAEALTE 506
|
|
| 46 |
PHA02562 |
endonuclease subunit; Provisional |
289-510 |
1.72e-05 |
|
endonuclease subunit; Provisional
Pssm-ID: 222878 [Multi-domain] Cd Length: 562 Bit Score: 48.86 E-value: 1.72e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 289 LEKELQTQTTEFHQNQDKIMAKLTNEDSQNRQLRQKLAALSRQIDELEETNRSLRKAEEELQD-IKDKINKGEYGNSGIM 367
Cdd:PHA02562 179 LNQQIQTLDMKIDHIQQQIKTYNKNIEEQRKKNGENIARKQNKYDELVEEAKTIKAEIEELTDeLLNLVMDIEDPSAALN 258
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 368 DEVDELRKRVLDMEGKDEElIKMEE----------QCRDLNKRLEKETVQSKDFKLEVDKLSVRITALEKLEDALDKSKQ 437
Cdd:PHA02562 259 KLNTAAAKIKSKIEQFQKV-IKMYEkggvcptctqQISEGPDRITKIKDKLKELQHSLEKLDTAIDELEEIMDEFNEQSK 337
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 295424207 438 ECYSLKCNLEKEKMTTKQLSEELESLNARIKELEAiESRLEKTEI-TLKDDLTKL---KTLTVMLVDERKTMSEKLK 510
Cdd:PHA02562 338 KLLELKNKISTNKQSLITLVDKAKKVKAAIEELQA-EFVDNAEELaKLQDELDKIvktKSELVKEKYHRGIVTDLLK 413
|
|
| PRK11281 |
PRK11281 |
mechanosensitive channel MscK; |
430-765 |
1.86e-05 |
|
mechanosensitive channel MscK;
Pssm-ID: 236892 [Multi-domain] Cd Length: 1113 Bit Score: 49.14 E-value: 1.86e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 430 DALDKSKQecyslkcNLEKEKMTTKQLSEELESLNAR---IKELEAIESRLEKTEITLKDDLTKLKTLTVMLVDERKTMS 506
Cdd:PRK11281 46 DALNKQKL-------LEAEDKLVQQDLEQTLALLDKIdrqKEETEQLKQQLAQAPAKLRQAQAELEALKDDNDEETRETL 118
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 507 EK--LKQTEDKLQSTTSQLQAEQNKVTTVTEKLIeetkrALKSKTD-AEEKMYSVTKERDDLRNKLKAEEEKGHDLL-SK 582
Cdd:PRK11281 119 STlsLRQLESRLAQTLDQLQNAQNDLAEYNSQLV-----SLQTQPErAQAALYANSQRLQQIRNLLKGGKVGGKALRpSQ 193
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 583 VTILKNRLQSLEAiekdfvKNKLNQDSSKSTAALhQE---------NNKIKELSQEVENLKLKLKDMKAIEDDlmKTEDE 653
Cdd:PRK11281 194 RVLLQAEQALLNA------QNDLQRKSLEGNTQL-QDllqkqrdylTARIQRLEHQLQLLQEAINSKRLTLSE--KTVQE 264
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 654 YETLERryANERDKAQFLSQELEHAKmELAKYkLAEKTESSHE---------QWLFRRLQEEEaksghlsrevdALKEKI 724
Cdd:PRK11281 265 AQSQDE--AARIQANPLVAQELEINL-QLSQR-LLKATEKLNTltqqnlrvkNWLDRLTQSER-----------NIKEQI 329
|
330 340 350 360
....*....|....*....|....*....|....*....|....*...
gi 295424207 725 HEymatedlichLQGdhSL-LQKKLNQQENR------NRDLGREIENL 765
Cdd:PRK11281 330 SV----------LKG--SLlLSRILYQQQQAlpsadlIEGLADRIADL 365
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
150-485 |
2.02e-05 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 48.91 E-value: 2.02e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 150 ESHR-RILEQLLMVERSHRQTIMEMEEEKRKHKEYMKKSDEFINLlEQECERLKKLIDQETASQEKKEQEKEKRIKTLKE 228
Cdd:PRK03918 447 EEHRkELLEEYTAELKRIEKELKEIEEKERKLRKELRELEKVLKK-ESELIKLKELAEQLKELEEKLKKYNLEELEKKAE 525
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 229 ELTKLKSFALMVVDEQQRLTAQLalqrqkiqaltTSAKETQGKLALAEARAQEEEQKATRLEKELQTQTTEfhqnqdkim 308
Cdd:PRK03918 526 EYEKLKEKLIKLKGEIKSLKKEL-----------EKLEELKKKLAELEKKLDELEEELAELLKELEELGFE--------- 585
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 309 akltnedsqnrqlrqKLAALSRQIDELEETNR---SLRKAEEELQDIKDKINKGEygnsgimDEVDELRKRVLDMEGKDE 385
Cdd:PRK03918 586 ---------------SVEELEERLKELEPFYNeylELKDAEKELEREEKELKKLE-------EELDKAFEELAETEKRLE 643
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 386 ELikmEEQCRDLNKRLEKETVQSKDFKLEvdKLSVRITALEKLEDALDKSKQECYSLKCNLEKEKMTTKQLSEELESLNA 465
Cdd:PRK03918 644 EL---RKELEELEKKYSEEEYEELREEYL--ELSRELAGLRAELEELEKRREEIKKTLEKLKEELEEREKAKKELEKLEK 718
|
330 340
....*....|....*....|
gi 295424207 466 RIKELEAIESRLEKTEITLK 485
Cdd:PRK03918 719 ALERVEELREKVKKYKALLK 738
|
|
| 46 |
PHA02562 |
endonuclease subunit; Provisional |
153-420 |
2.88e-05 |
|
endonuclease subunit; Provisional
Pssm-ID: 222878 [Multi-domain] Cd Length: 562 Bit Score: 48.09 E-value: 2.88e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 153 RRILEQLLMVershrQTIMEME----EEKRKHKEYMKKSDEFINLLEQECERLKKLIDQETASQEKKEQEKEKRIKTLKE 228
Cdd:PHA02562 153 RKLVEDLLDI-----SVLSEMDklnkDKIRELNQQIQTLDMKIDHIQQQIKTYNKNIEEQRKKNGENIARKQNKYDELVE 227
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 229 ELTKLKSfalmvvdEQQRLTAQLALQRQKIQALTTSAKetqgKLALAEARAQEEEQKATRLEKELQ------TQTTEFHQ 302
Cdd:PHA02562 228 EAKTIKA-------EIEELTDELLNLVMDIEDPSAALN----KLNTAAAKIKSKIEQFQKVIKMYEkggvcpTCTQQISE 296
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 303 NQDKImAKLTNedsQNRQLRQKLAALSRQIDELEETNRSLRKAEEELQDIKDKINKGEYGNSGIMDEVDELRKrvlDMEG 382
Cdd:PHA02562 297 GPDRI-TKIKD---KLKELQHSLEKLDTAIDELEEIMDEFNEQSKKLLELKNKISTNKQSLITLVDKAKKVKA---AIEE 369
|
250 260 270
....*....|....*....|....*....|....*...
gi 295424207 383 KDEELIKMEEQCRDLNKRLEKETVQSKDFKLEVDKLSV 420
Cdd:PHA02562 370 LQAEFVDNAEELAKLQDELDKIVKTKSELVKEKYHRGI 407
|
|
| CwlO1 |
COG3883 |
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ... |
315-529 |
3.02e-05 |
|
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];
Pssm-ID: 443091 [Multi-domain] Cd Length: 379 Bit Score: 47.52 E-value: 3.02e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 315 DSQNRQLRQKLAALSRQIDELEETnrsLRKAEEELQDIKDKINKGEygnsgimDEVDELRKRvldMEGKDEELIKMEEQC 394
Cdd:COG3883 15 DPQIQAKQKELSELQAELEAAQAE---LDALQAELEELNEEYNELQ-------AELEALQAE---IDKLQAEIAEAEAEI 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 395 RDLNKRLEKETVQSKDFKLEVDKLSV------------RITALEKLEDALDKSKQECYSLKCNLEKEKmttKQLSEELES 462
Cdd:COG3883 82 EERREELGERARALYRSGGSVSYLDVllgsesfsdfldRLSALSKIADADADLLEELKADKAELEAKK---AELEAKLAE 158
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 295424207 463 LNARIKELEAIESRLEKTEITLKDDLTKLKTLTVMLVDERKTMSEKLKQTEDKLQSTTSQLQAEQNK 529
Cdd:COG3883 159 LEALKAELEAAKAELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAA 225
|
|
| DUF4407 |
pfam14362 |
Domain of unknown function (DUF4407); This family of proteins is found in bacteria. Proteins ... |
290-431 |
3.11e-05 |
|
Domain of unknown function (DUF4407); This family of proteins is found in bacteria. Proteins in this family are typically between 366 and 597 amino acids in length. There is a single completely conserved residue R that may be functionally important.
Pssm-ID: 464151 [Multi-domain] Cd Length: 295 Bit Score: 47.25 E-value: 3.11e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 290 EKELQTQTTEFHQN-QDKIMAKLTNE-DSQNRQLRQKLAALSRQIDELE-ETNRSLRKAEEEL-QDIKDKINKGEYGNSG 365
Cdd:pfam14362 105 EKEIDRELLEIQQEeADAAKAQLAAAyRARLAELEAQIAALDAEIDAAEaRLDALQAEARCELdGTPGTGTGVPGDGPVA 184
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 295424207 366 --IMDEVDELRKRVLDMEGK-DEELIKMEEQCRDLNKRLEKETVQSKDFKLEVDKLSVRITALEKLEDA 431
Cdd:pfam14362 185 ktKQAQLDAAQAELAALQAQnDARLAALRAELARLTAERAAARARSQAAIDGDDGLLARLEALNRLTTE 253
|
|
| 46 |
PHA02562 |
endonuclease subunit; Provisional |
397-649 |
3.56e-05 |
|
endonuclease subunit; Provisional
Pssm-ID: 222878 [Multi-domain] Cd Length: 562 Bit Score: 47.70 E-value: 3.56e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 397 LNKRLEKE-TVQSKDFKLEVDKLSVRITALEKLEDALDK-SKQECYSLKCNLEKEKMTTKQLSEELESLNARIKELEaie 474
Cdd:PHA02562 171 LNKDKIRElNQQIQTLDMKIDHIQQQIKTYNKNIEEQRKkNGENIARKQNKYDELVEEAKTIKAEIEELTDELLNLV--- 247
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 475 srleKTEITLKDDLTKLKTLTVMLVDERKTMS--EKLKQTEDKLQSTTSQLQAEQNKVTTVTEKLIEETKRaLKSKTDAE 552
Cdd:PHA02562 248 ----MDIEDPSAALNKLNTAAAKIKSKIEQFQkvIKMYEKGGVCPTCTQQISEGPDRITKIKDKLKELQHS-LEKLDTAI 322
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 553 EKMYSVTKERDDLRNKLkaeeekgHDLLSKVTILKNRLQSLEAIEKDFVK--NKLNQDSSKSTAALHQENNKIKELSQEV 630
Cdd:PHA02562 323 DELEEIMDEFNEQSKKL-------LELKNKISTNKQSLITLVDKAKKVKAaiEELQAEFVDNAEELAKLQDELDKIVKTK 395
|
250
....*....|....*....
gi 295424207 631 ENLKLKlKDMKAIEDDLMK 649
Cdd:PHA02562 396 SELVKE-KYHRGIVTDLLK 413
|
|
| PRK01156 |
PRK01156 |
chromosome segregation protein; Provisional |
223-790 |
4.28e-05 |
|
chromosome segregation protein; Provisional
Pssm-ID: 100796 [Multi-domain] Cd Length: 895 Bit Score: 47.97 E-value: 4.28e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 223 IKTLKEELTKLKSfalmVVDEQQRLTAQLALQRQKIQALTTSAKETQGKLALAEARAQEEEQKATRLEKELQTQTTEFhQ 302
Cdd:PRK01156 161 INSLERNYDKLKD----VIDMLRAEISNIDYLEEKLKSSNLELENIKKQIADDEKSHSITLKEIERLSIEYNNAMDDY-N 235
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 303 NQDKIMAKLTNEDSQNRQLRQKLAALSRQIDELEETNRSLRKAEEELQDIkdkINKGEYGNSGIMDEVDELRKRVLD--- 379
Cdd:PRK01156 236 NLKSALNELSSLEDMKNRYESEIKTAESDLSMELEKNNYYKELEERHMKI---INDPVYKNRNYINDYFKYKNDIENkkq 312
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 380 -MEGKDEELIKMEEQCRDLNKrLEKETVQSKDFKLEVDKLSVRITALEKLEDALDKSKQECYSLKCNLEKEKMTTKQLSE 458
Cdd:PRK01156 313 iLSNIDAEINKYHAIIKKLSV-LQKDYNDYIKKKSRYDDLNNQILELEGYEMDYNSYLKSIESLKKKIEEYSKNIERMSA 391
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 459 EL-ESLNARIKELEAIESRLEKTEITLKDDLTKLKTLTVMLvderktmsEKLKQTEDKLQSTTSQLQAeQNKVTTVTEKL 537
Cdd:PRK01156 392 FIsEILKIQEIDPDAIKKELNEINVKLQDISSKVSSLNQRI--------RALRENLDELSRNMEMLNG-QSVCPVCGTTL 462
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 538 IEETKRALKSktDAEEKMYSVTKERDDLRNKLKAEEEKGHDLLSkvtiLKNRLQSlEAIEKDFVKNKLNQDSSKSTAALH 617
Cdd:PRK01156 463 GEEKSNHIIN--HYNEKKSRLEEKIREIEIEVKDIDEKIVDLKK----RKEYLES-EEINKSINEYNKIESARADLEDIK 535
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 618 QENNKIKELSQEVENLKLKLKDMKaIEDDLMKTEDEYETLERRYA----NERDKAQFLSQELEHAKMELAKYKLAEKTES 693
Cdd:PRK01156 536 IKINELKDKHDKYEEIKNRYKSLK-LEDLDSKRTSWLNALAVISLidieTNRSRSNEIKKQLNDLESRLQEIEIGFPDDK 614
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 694 SHEQWLFRRLQEE-------EAKSGHLSREVDALKEKIHEYMATEDLICHLQGDHSLLQKKLNQQENRNRDLGREIENLT 766
Cdd:PRK01156 615 SYIDKSIREIENEannlnnkYNEIQENKILIEKLRGKIDNYKKQIAEIDSIIPDLKEITSRINDIEDNLKKSRKALDDAK 694
|
570 580
....*....|....*....|....*.
gi 295424207 767 KELERYRHFSKSLRPSLNE--RRISD 790
Cdd:PRK01156 695 ANRARLESTIEILRTRINElsDRIND 720
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
590-773 |
6.97e-05 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 47.07 E-value: 6.97e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 590 LQSLEAIEKDFVKNKLNQDSSKSTAALHQENNKIKELSQEVENLKLKLKDMKAIEDDLMKTEDEYETLERRYANERDKAQ 669
Cdd:COG4717 40 LAFIRAMLLERLEKEADELFKPQGRKPELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELE 119
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 670 FLSQELEHAKMELAKYKLAEKTESSHEQWlfRRLQEEEAKSGHLSREVDALKEKIHEY------------MATEDLICHL 737
Cdd:COG4717 120 KLEKLLQLLPLYQELEALEAELAELPERL--EELEERLEELRELEEELEELEAELAELqeeleelleqlsLATEEELQDL 197
|
170 180 190
....*....|....*....|....*....|....*.
gi 295424207 738 QGDHSLLQKKLNQQENRNRDLGREIENLTKELERYR 773
Cdd:COG4717 198 AEELEELQQRLAELEEELEEAQEELEELEEELEQLE 233
|
|
| COG5283 |
COG5283 |
Phage-related tail protein [Mobilome: prophages, transposons]; |
235-401 |
7.18e-05 |
|
Phage-related tail protein [Mobilome: prophages, transposons];
Pssm-ID: 444094 [Multi-domain] Cd Length: 747 Bit Score: 47.16 E-value: 7.18e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 235 SFALMVVDeqQRLTAQLALQRQKIQALTTSAKETQGKLALAEARAQEEEQKATRLEKELQTQTTEFHQNQDKIMA---KL 311
Cdd:COG5283 2 QVILGAVD--KPFKSALESAKQRVAALAQALKALEAPTRALARALERAKQAAARLQTKYNKLRQSLQRLRQALDQagiDT 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 312 TNEDSQNRQLRQKLAALSRQIDELEETNRSLRKAEEELQDIKDKINK-GEYGNSGI-------------MDEVDELR--K 375
Cdd:COG5283 80 RQLSAAQRRLRSSLEQTNRQLERQQQRLARLGARQDRLKAARARLQRlAGAGAAAAaigaalaasvkpaIDFEDAMAdvA 159
|
170 180
....*....|....*....|....*.
gi 295424207 376 RVLDMEGKDEELIKMEEQCRDLNKRL 401
Cdd:COG5283 160 ATVDLDKSSEQFKALGKQARELSAQT 185
|
|
| Myosin_tail_1 |
pfam01576 |
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ... |
195-658 |
7.45e-05 |
|
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.
Pssm-ID: 460256 [Multi-domain] Cd Length: 1081 Bit Score: 47.09 E-value: 7.45e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 195 EQECERLKKLIDQETASQEKKEQEKEKRIKTLKEELTKlksfalmvvDEQQRLTAQLALQRQKiQALTTSAKETQGKLAL 274
Cdd:pfam01576 326 EQEVTELKKALEEETRSHEAQLQEMRQKHTQALEELTE---------QLEQAKRNKANLEKAK-QALESENAELQAELRT 395
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 275 AEARAQEEEQKATRLEKELQtqttefhqnqdKIMAKLTNEDSQNRQLRQKLAALSrqiDELEETNRSLRKAEEELQDIKD 354
Cdd:pfam01576 396 LQQAKQDSEHKRKKLEGQLQ-----------ELQARLSESERQRAELAEKLSKLQ---SELESVSSLLNEAEGKNIKLSK 461
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 355 KINKGEYGNSGIMDEVDELRKRVLDMEGKdeeLIKMEEQCRDLNKRLEKETVQSKDFKLEVDKLSVRITALEKledaldk 434
Cdd:pfam01576 462 DVSSLESQLQDTQELLQEETRQKLNLSTR---LRQLEDERNSLQEQLEEEEEAKRNVERQLSTLQAQLSDMKK------- 531
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 435 sKQECYSLkcNLEKEKMTTKQLSEELESLNARIKELEAIESRLEKTEITLKDDltkLKTLTVMLVDERKTMSeklkqTED 514
Cdd:pfam01576 532 -KLEEDAG--TLEALEEGKKRLQRELEALTQQLEEKAAAYDKLEKTKNRLQQE---LDDLLVDLDHQRQLVS-----NLE 600
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 515 KLQSTTSQLQAEQNkvtTVTEKLIEETKRALKSKTDAEEKMYSVTKERDDLRNKLKAEEEkghdllskvtilKNRLQSLE 594
Cdd:pfam01576 601 KKQKKFDQMLAEEK---AISARYAEERDRAEAEAREKETRALSLARALEEALEAKEELER------------TNKQLRAE 665
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 295424207 595 AieKDFVKNKlnQDSSKStaaLHQENNKIKELSQEVENLKLKLKDMkaiEDDLMKTEDEYETLE 658
Cdd:pfam01576 666 M--EDLVSSK--DDVGKN---VHELERSKRALEQQVEEMKTQLEEL---EDELQATEDAKLRLE 719
|
|
| 235kDa-fam |
TIGR01612 |
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ... |
306-698 |
7.53e-05 |
|
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.
Pssm-ID: 130673 [Multi-domain] Cd Length: 2757 Bit Score: 47.35 E-value: 7.53e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 306 KIMAKLTNEDSQNRQLRQKLAALSRQIDELEETNRSLRKAEEE-LQDIKDKINKGEY-----GNSGIMDEVDELRKRVLD 379
Cdd:TIGR01612 483 KDIDENSKQDNTVKLILMRMKDFKDIIDFMELYKPDEVPSKNIiGFDIDQNIKAKLYkeieaGLKESYELAKNWKKLIHE 562
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 380 ----MEGKDEELIKMEEQCRDL-NKRLE--KETVQSKDFKLEVDklsvritalEKLEDALDKSK--QECYSLKCNLEKE- 449
Cdd:TIGR01612 563 ikkeLEEENEDSIHLEKEIKDLfDKYLEidDEIIYINKLKLELK---------EKIKNISDKNEyiKKAIDLKKIIENNn 633
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 450 -------KMTTKQLSEELESLNariKELEAIESRLEKTeitLKDDLTKLKTLTVMLVDERKTMSEKLKQTEDKLQSTTSQ 522
Cdd:TIGR01612 634 ayidelaKISPYQVPEHLKNKD---KIYSTIKSELSKI---YEDDIDALYNELSSIVKENAIDNTEDKAKLDDLKSKIDK 707
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 523 LQAEQNKVTTVTEKL----IEETKRALkSKTDAEEKMYSVTKERDDLRNKLKAEEEKGHDLLSKVTILKNrlqslEAIEK 598
Cdd:TIGR01612 708 EYDKIQNMETATVELhlsnIENKKNEL-LDIIVEIKKHIHGEINKDLNKILEDFKNKEKELSNKINDYAK-----EKDEL 781
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 599 DFVKNKLNQDSSKSTAALHQENNKIKELSQEVENLKLKLKDMKAIEDDLMKTEDEYETLERRYANERDKaqFLSQELEHa 678
Cdd:TIGR01612 782 NKYKSKISEIKNHYNDQINIDNIKDEDAKQNYDKSKEYIKTISIKEDEIFKIINEMKFMKDDFLNKVDK--FINFENNC- 858
|
410 420
....*....|....*....|
gi 295424207 679 kmelakyklAEKTESSHEQW 698
Cdd:TIGR01612 859 ---------KEKIDSEHEQF 869
|
|
| SMC_N |
pfam02463 |
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
248-666 |
8.51e-05 |
|
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 46.89 E-value: 8.51e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 248 TAQLALQRQKIQALTTSAKETQGKLALAEARAQEEEQKATRLEKELQTQTTEFHQnqdKIMAKLTNEDSQNRQLRQKLAA 327
Cdd:pfam02463 178 LIEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYL---KLNEERIDLLQELLRDEQEEIE 254
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 328 LSRQIDELEET--NRSLRKAEEELQDIKDKINKGEYGNSGIMDEVDELRKRVLDMEGKDEELIKMEEQCRDLNKRLEKET 405
Cdd:pfam02463 255 SSKQEIEKEEEklAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKKAEKELKKEK 334
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 406 VQSKDFKLEVDKLSVRITALEKLEDALDKSKQECYSLKCNLEKEKmttkqlSEELESLNARIKELEAIESRLEKTEITLK 485
Cdd:pfam02463 335 EEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKK------KLESERLSSAAKLKEEELELKSEEEKEAQ 408
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 486 DDLTKLKTLTVMLVDERKTMSEKLKqtedklqsttsqlqaeqnkvttVTEKLIEETKRALKSKTDAE--------EKMYS 557
Cdd:pfam02463 409 LLLELARQLEDLLKEEKKEELEILE----------------------EEEESIELKQGKLTEEKEELekqelkllKDELE 466
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 558 VTKERDDLRNKLKAEEEKGHDLLSKVTILKNRLQSLEAIEKDFVKNKLNQDSSKSTAALHQENNKIKelsQEVENLKLKL 637
Cdd:pfam02463 467 LKKSEDLLKETQLVKLQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGD---LGVAVENYKV 543
|
410 420
....*....|....*....|....*....
gi 295424207 638 KDMKAIEDDLMKTEDEYETLERRYANERD 666
Cdd:pfam02463 544 AISTAVIVEVSATADEVEERQKLVRALTE 572
|
|
| 235kDa-fam |
TIGR01612 |
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ... |
182-727 |
8.54e-05 |
|
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.
Pssm-ID: 130673 [Multi-domain] Cd Length: 2757 Bit Score: 46.97 E-value: 8.54e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 182 EYMKKSDEFINLLEQECERLKKLIDqeTASQEKKEQEKEKRIKTLKEELTKLKSfalmVVDEQQRLTAQLA------LQR 255
Cdd:TIGR01612 1136 EIKKKSENYIDEIKAQINDLEDVAD--KAISNDDPEEIEKKIENIVTKIDKKKN----IYDEIKKLLNEIAeiekdkTSL 1209
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 256 QKIQALTTSAKETQGKLALaeARAQEEEQKATRLEKELQTQTTEFHQNQDKiMAKLTNEDSQNRQLRQKLAALSRQIDEL 335
Cdd:TIGR01612 1210 EEVKGINLSYGKNLGKLFL--EKIDEEKKKSEHMIKAMEAYIEDLDEIKEK-SPEIENEMGIEMDIKAEMETFNISHDDD 1286
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 336 EETNRSLRKAEEELQDIKD---KINKGEYGNSGIMDEVDELRKRVLDMEGKDEE-------------------LIKMEEQ 393
Cdd:TIGR01612 1287 KDHHIISKKHDENISDIREkslKIIEDFSEESDINDIKKELQKNLLDAQKHNSDinlylneianiynilklnkIKKIIDE 1366
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 394 CRDLNKRLEKetvQSKDFKLEVDKLSVRITALE----------KLEDALD-KSKQECYS----LKCNLEKEKMTT----K 454
Cdd:TIGR01612 1367 VKEYTKEIEE---NNKNIKDELDKSEKLIKKIKddinleecksKIESTLDdKDIDECIKkikeLKNHILSEESNIdtyfK 1443
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 455 QLSEELESLNARIKELEAIESRLEKTEITLKDDLTKLKTLTVMLVDERKTMSEKLKQTEDKlqsttSQLQAEQNKV---- 530
Cdd:TIGR01612 1444 NADENNENVLLLFKNIEMADNKSQHILKIKKDNATNDHDFNINELKEHIDKSKGCKDEADK-----NAKAIEKNKElfeq 1518
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 531 --TTVTEKLIEETKRALKSKTDAEEKMYS-VTKERDDLRNKLKAEEEKGHDLLSKVTILKNRlqsleaIEKDFVKNklnq 607
Cdd:TIGR01612 1519 ykKDVTELLNKYSALAIKNKFAKTKKDSEiIIKEIKDAHKKFILEAEKSEQKIKEIKKEKFR------IEDDAAKN---- 1588
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 608 dsskstaalHQENNKIKELSQEVENLK---LKLKDMKAIEDDLMKtedEYETLERRYANerdkAQFLSQELEHAKMELAK 684
Cdd:TIGR01612 1589 ---------DKSNKAAIDIQLSLENFEnkfLKISDIKKKINDCLK---ETESIEKKISS----FSIDSQDTELKENGDNL 1652
|
570 580 590 600
....*....|....*....|....*....|....*....|...
gi 295424207 685 YKLAEKTESSHEQWlfRRLQEEEAKSGHLSREVDALKEKIHEY 727
Cdd:TIGR01612 1653 NSLQEFLESLKDQK--KNIEDKKKELDELDSEIEKIEIDVDQH 1693
|
|
| CwlO1 |
COG3883 |
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ... |
273-492 |
1.21e-04 |
|
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];
Pssm-ID: 443091 [Multi-domain] Cd Length: 379 Bit Score: 45.59 E-value: 1.21e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 273 ALAEARAQEEEQKATRLEKELQTQTTEFHQNQDKIMAKltneDSQNRQLRQKLAALSRQIDELEETNRSLRKAEEELQDI 352
Cdd:COG3883 12 AFADPQIQAKQKELSELQAELEAAQAELDALQAELEEL----NEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREE 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 353 KDKINKGEYGNSGIMDEVDELrkrvldMEGKDEElikmeeqcrDLNKRLEK-ETVQSKDFKLeVDKLSVRITALEKLEDA 431
Cdd:COG3883 88 LGERARALYRSGGSVSYLDVL------LGSESFS---------DFLDRLSAlSKIADADADL-LEELKADKAELEAKKAE 151
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 295424207 432 LDKSKQECYSLKcnlekekmttKQLSEELESLNARIKELEAIESRLEKTEITLKDDLTKLK 492
Cdd:COG3883 152 LEAKLAELEALK----------AELEAAKAELEAQQAEQEALLAQLSAEEAAAEAQLAELE 202
|
|
| MukB |
COG3096 |
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ... |
228-547 |
1.31e-04 |
|
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 442330 [Multi-domain] Cd Length: 1470 Bit Score: 46.48 E-value: 1.31e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 228 EELTKLKSfalMVVDEQQRLTAQ--LALQ-RQKIQALttsaKETQGKLALAEARAQEEEQKATRLEKELQTQTTEFHQNQ 304
Cdd:COG3096 389 EEVDSLKS---QLADYQQALDVQqtRAIQyQQAVQAL----EKARALCGLPDLTPENAEDYLAAFRAKEQQATEEVLELE 461
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 305 DKimakLTNEDSQNRQLRQKLAALSRQIDELEeTNRSLRKAEEELQDIKDKINkgeygnsgIMDEVDELRKRVLDMEGKD 384
Cdd:COG3096 462 QK----LSVADAARRQFEKAYELVCKIAGEVE-RSQAWQTARELLRRYRSQQA--------LAQRLQQLRAQLAELEQRL 528
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 385 EELIKMEEQCRDLNKRLEKEtVQSKDfklevdklsvritALEKLEDALDKSKQECYSLKCNLEKEKMTTKQlseELESLN 464
Cdd:COG3096 529 RQQQNAERLLEEFCQRIGQQ-LDAAE-------------ELEELLAELEAQLEELEEQAAEAVEQRSELRQ---QLEQLR 591
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 465 ARIKELEAIESRLekteITLKDDLTKLktltvmlvderktmSEKLKQTEDKLQSTTSQLQ--AEQNKVTTVTEKLIEETK 542
Cdd:COG3096 592 ARIKELAARAPAW----LAAQDALERL--------------REQSGEALADSQEVTAAMQqlLEREREATVERDELAARK 653
|
....*
gi 295424207 543 RALKS 547
Cdd:COG3096 654 QALES 658
|
|
| PspC_subgroup_1 |
NF033838 |
pneumococcal surface protein PspC, choline-binding form; The pneumococcal surface protein PspC, ... |
278-697 |
1.54e-04 |
|
pneumococcal surface protein PspC, choline-binding form; The pneumococcal surface protein PspC, as described in Streptococcus pneumoniae, is a repetitive and highly variable protein, recognized by a conserved N-terminal domain and also by genomic location. This form, subgroup 1, has variable numbers of a choline-binding repeat in the C-terminal region, and is also known as choline-binding protein A. The other form, subgroup 2, is anchored covalently after cleavage by sortase at a C-terminal LPXTG site.
Pssm-ID: 468201 [Multi-domain] Cd Length: 684 Bit Score: 45.77 E-value: 1.54e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 278 RAQEEEQK-ATRLEKELQTQTTEFHQNQDKimakltNEDSQNRQLRQKLAALSRQIdeLEETNRSLRKAEEEL-QDIKDK 355
Cdd:NF033838 51 SGNESQKEhAKEVESHLEKILSEIQKSLDK------RKHTQNVALNKKLSDIKTEY--LYELNVLKEKSEAELtSKTKKE 122
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 356 INKGeygNSGIMDEVDELRKRVLDMEGKDEELIKMEEQCRDLNKRlEKETVQSKDFKLEVDKLSVRITalekledaldKS 435
Cdd:NF033838 123 LDAA---FEQFKKDTLEPGKKVAEATKKVEEAEKKAKDQKEEDRR-NYPTNTYKTLELEIAESDVEVK----------KA 188
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 436 KQECYSLKCNLEKEKMTTKQLSEELESLNARIKELEAIESRLEKTEITLKDDL-TKLKTLTVMLVD--ERKTMSEKLKQ- 511
Cdd:NF033838 189 ELELVKEEAKEPRDEEKIKQAKAKVESKKAEATRLEKIKTDREKAEEEAKRRAdAKLKEAVEKNVAtsEQDKPKRRAKRg 268
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 512 ------TEDKlqsttSQLQAEQNKVTTVTEKLIEETKRALKSKTDAEEKMYSVTKerddlrnklKAEEEKGHDLLSKVTI 585
Cdd:NF033838 269 vlgepaTPDK-----KENDAKSSDSSVGEETLPSPSLKPEKKVAEAEKKVEEAKK---------KAKDQKEEDRRNYPTN 334
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 586 LKNRLQsLEAIEKDFVKNKLNQDSSKSTAALHQENNKIKELSQEVENLKLKLKDMKAIEDDLMKTEDEyetlERRYANER 665
Cdd:NF033838 335 TYKTLE-LEIAESDVKVKEAELELVKEEAKEPRNEEKIKQAKAKVESKKAEATRLEKIKTDRKKAEEE----AKRKAAEE 409
|
410 420 430
....*....|....*....|....*....|..
gi 295424207 666 DKAQFLSQELEHAKMELAKYKLAEKTESSHEQ 697
Cdd:NF033838 410 DKVKEKPAEQPQPAPAPQPEKPAPKPEKPAEQ 441
|
|
| COG5022 |
COG5022 |
Myosin heavy chain [General function prediction only]; |
182-659 |
1.75e-04 |
|
Myosin heavy chain [General function prediction only];
Pssm-ID: 227355 [Multi-domain] Cd Length: 1463 Bit Score: 45.84 E-value: 1.75e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 182 EYMKKSDEFINLLEQECERLKKLidqetasQEKKEQEKEKRIKTLKEELTklKSFalmvvdeqQRLTAQLALQRQKIQAl 261
Cdd:COG5022 810 KEYRSYLACIIKLQKTIKREKKL-------RETEEVEFSLKAEVLIQKFG--RSL--------KAKKRFSLLKKETIYL- 871
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 262 ttsakETQGKLALAEARAQEEEQKATRLEK------ELQTQTTEFHQNQDkimaklTNEDSQNRQLRQKLAALSRQIDEL 335
Cdd:COG5022 872 -----QSAQRVELAERQLQELKIDVKSISSlklvnlELESEIIELKKSLS------SDLIENLEFKTELIARLKKLLNNI 940
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 336 EETNRSLRKAEEelQDIKDKINKGEygnsGIMDEVDELRKRVLDMEGKDE-ELIKMEEQCRDLNKRLEKETVQSKDFKLE 414
Cdd:COG5022 941 DLEEGPSIEYVK--LPELNKLHEVE----SKLKETSEEYEDLLKKSTILVrEGNKANSELKNFKKELAELSKQYGALQES 1014
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 415 VDKLSVRITALEKLEDALDKSKQECYSLKcNLEKEKMTTKQLSEELESLNARIKELE---AIESRLEKTEITLKDDLTKL 491
Cdd:COG5022 1015 TKQLKELPVEVAELQSASKIISSESTELS-ILKPLQKLKGLLLLENNQLQARYKALKlrrENSLLDDKQLYQLESTENLL 1093
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 492 KTLTVMLVDERKTMSEKLKQTEDKLQSTTSQLQAEQ----------------NKVTTVTEKLIEETKRALKSKTDAEEKM 555
Cdd:COG5022 1094 KTINVKDLEVTNRNLVKPANVLQFIVAQMIKLNLLQeiskflsqlvntlepvFQKLSVLQLELDGLFWEANLEALPSPPP 1173
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 556 YSVTKERDDLRNKLKaeEEKGHDLLSKVTILKNRLQSLEAIEK-DFVKNKLNQDSSKSTAALHQEN---------NKIKE 625
Cdd:COG5022 1174 FAALSEKRLYQSALY--DEKSKLSSSEVNDLKNELIALFSKIFsGWPRGDKLKKLISEGWVPTEYStslkgfnnlNKKFD 1251
|
490 500 510
....*....|....*....|....*....|....
gi 295424207 626 LSQEVENLKLkLKDMKAIEDDLMKTEDEYETLER 659
Cdd:COG5022 1252 TPASMSNEKL-LSLLNSIDNLLSSYKLEEEVLPA 1284
|
|
| PRK01156 |
PRK01156 |
chromosome segregation protein; Provisional |
140-707 |
1.91e-04 |
|
chromosome segregation protein; Provisional
Pssm-ID: 100796 [Multi-domain] Cd Length: 895 Bit Score: 45.66 E-value: 1.91e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 140 ELDKVVEKHKESHRRILEQLLMVERSHR-----QTIMEMEEEKRKHKEYMKKSDEFINLleqECERLKKLIDQETASqek 214
Cdd:PRK01156 139 EMDSLISGDPAQRKKILDEILEINSLERnydklKDVIDMLRAEISNIDYLEEKLKSSNL---ELENIKKQIADDEKS--- 212
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 215 kEQEKEKRIKTLKEELTKLKSFALMVVDEQQRLTAQLalqrQKIQALTTSAKETQGKLALAEARAQEEEQKATRLEK--- 291
Cdd:PRK01156 213 -HSITLKEIERLSIEYNNAMDDYNNLKSALNELSSLE----DMKNRYESEIKTAESDLSMELEKNNYYKELEERHMKiin 287
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 292 --------ELQTQTTEFHQ--NQDKIMAKLTNEDSQNRQLRQKLAALSRQIDELEETNRSLRKAEEELQDIK-DKINKGE 360
Cdd:PRK01156 288 dpvyknrnYINDYFKYKNDieNKKQILSNIDAEINKYHAIIKKLSVLQKDYNDYIKKKSRYDDLNNQILELEgYEMDYNS 367
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 361 YGNS--GIMDEVDELRKRVLDMEGKDEELIKMEEQCRD-LNKRLEKETVQSKDFKLEVDKLSVRITALEKLEDALDKSKQ 437
Cdd:PRK01156 368 YLKSieSLKKKIEEYSKNIERMSAFISEILKIQEIDPDaIKKELNEINVKLQDISSKVSSLNQRIRALRENLDELSRNME 447
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 438 ECYSL-KCNLEKEKMTTKQLSEELESLNariKELEAIESRLEKTEITLKDDLTKLKTLTVMLVDERKTMSEKLKQTEDKL 516
Cdd:PRK01156 448 MLNGQsVCPVCGTTLGEEKSNHIINHYN---EKKSRLEEKIREIEIEVKDIDEKIVDLKKRKEYLESEEINKSINEYNKI 524
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 517 QSTTSQLQAEQNKVTTVTEK------LIEETKRA----LKSKTDAEEKMYSVTKERDDLRNKLKAEEEKghdllSKVTIL 586
Cdd:PRK01156 525 ESARADLEDIKIKINELKDKhdkyeeIKNRYKSLkledLDSKRTSWLNALAVISLIDIETNRSRSNEIK-----KQLNDL 599
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 587 KNRLQSLEaIEKDFVKNKLNQDSSKSTAALHQENNKIKELSQ---EVENLKLKLKDMKAIEDDLMKTEDEYETLERRYAN 663
Cdd:PRK01156 600 ESRLQEIE-IGFPDDKSYIDKSIREIENEANNLNNKYNEIQEnkiLIEKLRGKIDNYKKQIAEIDSIIPDLKEITSRIND 678
|
570 580 590 600
....*....|....*....|....*....|....*....|....
gi 295424207 664 ERDKAQFLSQELEHAKMELAKYKLAEKTESSHEQWLFRRLQEEE 707
Cdd:PRK01156 679 IEDNLKKSRKALDDAKANRARLESTIEILRTRINELSDRINDIN 722
|
|
| CCCAP |
pfam15964 |
Centrosomal colon cancer autoantigen protein family; CCCAP is a family of proteins found in ... |
242-537 |
2.70e-04 |
|
Centrosomal colon cancer autoantigen protein family; CCCAP is a family of proteins found in eukaryotes. CCCAP is also known as SDCCAG8, serologically defined colon cancer antigen 8. It is associated with the centrosome.
Pssm-ID: 435040 [Multi-domain] Cd Length: 703 Bit Score: 45.28 E-value: 2.70e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 242 DEQQRLTAQLALQRQKIQALTTSAKETQGKLALAEARAQEEEQKATRLEKELQTQTTEFHQNQDKIMAKLTNEDSQNRQ- 320
Cdd:pfam15964 325 EAQQRESSAYEQVKQAVQMTEEANFEKTKALIQCEQLKSELERQKERLEKELASQQEKRAQEKEALRKEMKKEREELGAt 404
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 321 ---LRQKLAALSRQIDELEETNRSLRKAEEELQ---------------DIKDKINKGEYGNSGIMDEVDELRKRVL-DME 381
Cdd:pfam15964 405 mlaLSQNVAQLEAQVEKVTREKNSLVSQLEEAQkqlasqemdvtkvcgEMRYQLNQTKMKKDEAEKEHREYRTKTGrQLE 484
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 382 GKDEELIKMEEQCRDLNKRLEKETVQSKDFKLEVDKLSvriTALEKLEDALDKSKQECYSLKCNLEKE-KMTTKQLSEEL 460
Cdd:pfam15964 485 IKDQEIEKLGLELSESKQRLEQAQQDAARAREECLKLT---ELLGESEHQLHLTRLEKESIQQSFSNEaKAQALQAQQRE 561
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 295424207 461 ESLNARIKELEAiesRLEKTEITLKDDLTKLKTLTVMLVDERKTMSEKLKQTEDKLQSTTSQLQAEQNKVTTVTEKL 537
Cdd:pfam15964 562 QELTQKMQQMEA---QHDKTVNEQYSLLTSQNTFIAKLKEECCTLAKKLEEITQKSRSEVEQLSQEKEYLQDRLEKL 635
|
|
| CagA_N |
pfam18971 |
CagA protein; The Helicobacter pylori type IV secretion effector CagA is a major bacterial ... |
244-530 |
3.27e-04 |
|
CagA protein; The Helicobacter pylori type IV secretion effector CagA is a major bacterial virulence determinant and critical for gastric carcinogenesis. X-ray crystallographic analysis of the N-terminal CagA fragment (residues 1-876) revealed that the region has a structure comprised of three discrete domains. Domain I constitutes a mobile CagA N terminus, while Domain II tethers CagA to the plasma membrane by interacting with membrane phosphatidylserine. Domain III interacts intramolecularly with the intrinsically disordered C-terminal region, and this interaction potentiates the pathogenic scaffold/hub function of CagA.
Pssm-ID: 408741 [Multi-domain] Cd Length: 876 Bit Score: 44.76 E-value: 3.27e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 244 QQRLTAQ-LALQRQK--IQALTTSAKETQGKL-----ALAEARAQEEEQKATRLEKELQTQTTEFHQNQDKIMAKLTNED 315
Cdd:pfam18971 562 ENKLTAKgLSLQEANklIKDFLSSNKELAGKAlnfnkAVAEAKSTGNYDEVKKAQKDLEKSLRKREHLEKEVEKKLESKS 641
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 316 SQNRQLRQKLAALSrQIDEL-----EETNR---------SLRKAEEELQDIKDKINKGEYGNSGIMDEVDelrkrvldmE 381
Cdd:pfam18971 642 GNKNKMEAKAQANS-QKDEIfalinKEANRdaraiaytqNLKGIKRELSDKLEKISKDLKDFSKSFDEFK---------N 711
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 382 GKDEELIKMEEQCRDLNKRLeKETVQSKDFKLEVDKLSvriTALEKLEDALDKSKQECYSLKCNLE---KEKMTTKQLSE 458
Cdd:pfam18971 712 GKNKDFSKAEETLKALKGSV-KDLGINPEWISKVENLN---AALNEFKNGKNKDFSKVTQAKSDLEnsvKDVIINQKVTD 787
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 295424207 459 ELESLNARIKELEAIE--SRLEKTeitlkddLTKLKTLTvmlvdeRKTMSEKLKQTEDKLQSTTSQL-QAEQNKV 530
Cdd:pfam18971 788 KVDNLNQAVSVAKAMGdfSRVEQV-------LADLKNFS------KEQLAQQAQKNEDFNTGKNSELyQSVKNSV 849
|
|
| DR0291 |
COG1579 |
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ... |
315-480 |
3.93e-04 |
|
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];
Pssm-ID: 441187 [Multi-domain] Cd Length: 236 Bit Score: 43.37 E-value: 3.93e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 315 DSQNRQLRQKLAALSRQIDELEET----NRSLRKAEEELQDIKDKINKGEygnsgimDEVDELRKRVLDMEGKDEELIKM 390
Cdd:COG1579 16 DSELDRLEHRLKELPAELAELEDElaalEARLEAAKTELEDLEKEIKRLE-------LEIEEVEARIKKYEEQLGNVRNN 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 391 EEQcRDLNKRLEKEtvqskdfKLEVDKLSVRI----TALEKLEDALDKSKQECYSLKCNLEKEKmttKQLSEELESLNAR 466
Cdd:COG1579 89 KEY-EALQKEIESL-------KRRISDLEDEIlelmERIEELEEELAELEAELAELEAELEEKK---AELDEELAELEAE 157
|
170
....*....|....
gi 295424207 467 IKELEAIESRLEKT 480
Cdd:COG1579 158 LEELEAEREELAAK 171
|
|
| 235kDa-fam |
TIGR01612 |
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ... |
175-687 |
4.03e-04 |
|
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.
Pssm-ID: 130673 [Multi-domain] Cd Length: 2757 Bit Score: 44.66 E-value: 4.03e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 175 EEKRKHKEYMKKSDEFINLLEQECERLKKLIDQETasqeKKEQEKEKRIKTLKEELTKLKSFA-------LMVVDEQQRL 247
Cdd:TIGR01612 907 EEEYQNINTLKKVDEYIKICENTKESIEKFHNKQN----ILKEILNKNIDTIKESNLIEKSYKdkfdntlIDKINELDKA 982
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 248 TAQLAL-----QRQKIQALTTSAKETQGK---------LALAEARAQEEEQKATRLEKELQTQTTEFHQNQDKIMAKLTN 313
Cdd:TIGR01612 983 FKDASLndyeaKNNELIKYFNDLKANLGKnkenmlyhqFDEKEKATNDIEQKIEDANKNIPNIEIAIHTSIYNIIDEIEK 1062
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 314 EDSQNRQLrqklaaLSRQIdeLEETNRSLRKAEEelqdIKDKI---NKGEYGNSGIMDEVDELRKRVLDMEGKDEELIKM 390
Cdd:TIGR01612 1063 EIGKNIEL------LNKEI--LEEAEINITNFNE----IKEKLkhyNFDDFGKEENIKYADEINKIKDDIKNLDQKIDHH 1130
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 391 EEQCRDLNKRLEKetvqskdfklEVDKLSVRITALEKLEDAL--DKSKQECYSLKCNLEKEKMTTKQLSEELESLNARIK 468
Cdd:TIGR01612 1131 IKALEEIKKKSEN----------YIDEIKAQINDLEDVADKAisNDDPEEIEKKIENIVTKIDKKKNIYDEIKKLLNEIA 1200
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 469 ELEAIESRLEKTEITLKDDLTKLKTLTVMLVDERKTMSEKLKQTEDKLQSTTSQL--QAEQNKVTTVTEKLIEETKRALK 546
Cdd:TIGR01612 1201 EIEKDKTSLEEVKGINLSYGKNLGKLFLEKIDEEKKKSEHMIKAMEAYIEDLDEIkeKSPEIENEMGIEMDIKAEMETFN 1280
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 547 SKTDAEEKMYSVTKERD----DLRNKlkaeeekghdlLSKVTILKNRLQSLEAIEKDFVKNKLnqDSSKSTAALHQENNK 622
Cdd:TIGR01612 1281 ISHDDDKDHHIISKKHDenisDIREK-----------SLKIIEDFSEESDINDIKKELQKNLL--DAQKHNSDINLYLNE 1347
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 295424207 623 IKELSQevenlKLKLKDMKAIEDDLMKTEDEYETLERRYANERDKAQFLSQEL-EHAKMELAKYKL 687
Cdd:TIGR01612 1348 IANIYN-----ILKLNKIKKIIDEVKEYTKEIEENNKNIKDELDKSEKLIKKIkDDINLEECKSKI 1408
|
|
| PRK12704 |
PRK12704 |
phosphodiesterase; Provisional |
267-425 |
4.48e-04 |
|
phosphodiesterase; Provisional
Pssm-ID: 237177 [Multi-domain] Cd Length: 520 Bit Score: 44.38 E-value: 4.48e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 267 ETQGKLALAEARaQEEEQKATRLEKELQTQTTEFHQNQDKIMAKLTNEDSQNRQLRQKLAALSRQIDELEETNRSLRKAE 346
Cdd:PRK12704 52 EAIKKEALLEAK-EEIHKLRNEFEKELRERRNELQKLEKRLLQKEENLDRKLELLEKREEELEKKEKELEQKQQELEKKE 130
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 347 EELQDIKDKINKGEYGNSGImdEVDELRKRVLDmegkdeeliKMEEQCRD----LNKRLEKETvqskdfKLEVDKLSVRI 422
Cdd:PRK12704 131 EELEELIEEQLQELERISGL--TAEEAKEILLE---------KVEEEARHeaavLIKEIEEEA------KEEADKKAKEI 193
|
...
gi 295424207 423 TAL 425
Cdd:PRK12704 194 LAQ 196
|
|
| mukB |
PRK04863 |
chromosome partition protein MukB; |
116-488 |
4.55e-04 |
|
chromosome partition protein MukB;
Pssm-ID: 235316 [Multi-domain] Cd Length: 1486 Bit Score: 44.56 E-value: 4.55e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 116 ALQRDAFQAKSApwQEDIYEKpMNELDKVVEKHKEShRRILEQLLMVERSHRQTIMEMEEEKRKHKEYMKKSDEFINLLE 195
Cdd:PRK04863 290 ELRRELYTSRRQ--LAAEQYR-LVEMARELAELNEA-ESDLEQDYQAASDHLNLVQTALRQQEKIERYQADLEELEERLE 365
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 196 QECErLKKLIDQETASQEKKEQEKEKRIKTLKEELTklksfalmvvDEQQRLTAQ--LALQ-RQKIQALTtSAKETQGKL 272
Cdd:PRK04863 366 EQNE-VVEEADEQQEENEARAEAAEEEVDELKSQLA----------DYQQALDVQqtRAIQyQQAVQALE-RAKQLCGLP 433
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 273 AL---------AEARAQEEEQKATRLEKELQTQTTEFHQNQ--------DKIMAKLTNEDSQN------------RQLRQ 323
Cdd:PRK04863 434 DLtadnaedwlEEFQAKEQEATEELLSLEQKLSVAQAAHSQfeqayqlvRKIAGEVSRSEAWDvarellrrlreqRHLAE 513
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 324 KLAALSRQIDELEETNRSLRKAEEELQDIKDKINKGEYGNsgimDEVDELRkrvldmEGKDEELIKMEEQCRDLNKRLEK 403
Cdd:PRK04863 514 QLQQLRMRLSELEQRLRQQQRAERLLAEFCKRLGKNLDDE----DELEQLQ------EELEARLESLSESVSEARERRMA 583
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 404 ETVQSKDFKLEVDKLSVRIT-------ALEKLED---ALDKSKQECYSLKCN-LEKEKMTTK---QLSEELESLNARIKE 469
Cdd:PRK04863 584 LRQQLEQLQARIQRLAARAPawlaaqdALARLREqsgEEFEDSQDVTEYMQQlLERERELTVerdELAARKQALDEEIER 663
|
410
....*....|....*....
gi 295424207 470 LEAIESRLEKTEITLKDDL 488
Cdd:PRK04863 664 LSQPGGSEDPRLNALAERF 682
|
|
| PRK04778 |
PRK04778 |
septation ring formation regulator EzrA; Provisional |
271-775 |
4.73e-04 |
|
septation ring formation regulator EzrA; Provisional
Pssm-ID: 179877 [Multi-domain] Cd Length: 569 Bit Score: 44.06 E-value: 4.73e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 271 KLALAEARAQEEEQKATRLEKELQTQTT--EFHQNQDKIMAKltnedsqnrqlrqKLAALSRQIDELEETNRSLR--KAE 346
Cdd:PRK04778 38 KQELENLPVNDELEKVKKLNLTGQSEEKfeEWRQKWDEIVTN-------------SLPDIEEQLFEAEELNDKFRfrKAK 104
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 347 EELQDIKDKINKGEygnsgimDEVDELRKRVLDMEGKDEELIKMEEQCRDLNKRLEKeTVQSKDFKLEVdklsvritALE 426
Cdd:PRK04778 105 HEINEIESLLDLIE-------EDIEQILEELQELLESEEKNREEVEQLKDLYRELRK-SLLANRFSFGP--------ALD 168
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 427 KLEDALDKSKQECYSLKC-----NLEKEKMTTKQLSEELESLNARIKELEAIesrLEKTEITLKDDLTKLKTltvmlvDE 501
Cdd:PRK04778 169 ELEKQLENLEEEFSQFVEltesgDYVEAREILDQLEEELAALEQIMEEIPEL---LKELQTELPDQLQELKA------GY 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 502 RKTMSEKLKQTEDKLQSTTSQLQAEQNKVTTVTEKL-IEETKRALKSKTDAEEKMYS-----------VTKERDDLRNKL 569
Cdd:PRK04778 240 RELVEEGYHLDHLDIEKEIQDLKEQIDENLALLEELdLDEAEEKNEEIQERIDQLYDilerevkarkyVEKNSDTLPDFL 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 570 KAEEEKGHDLLSKVTILK-------NRLQSLEAIEKDFvkNKLNQDSSKSTAALHqenNKIKELSQEVENLKLKLKDMKA 642
Cdd:PRK04778 320 EHAKEQNKELKEEIDRVKqsytlneSELESVRQLEKQL--ESLEKQYDEITERIA---EQEIAYSELQEELEEILKQLEE 394
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 643 IEDDLMKTEDEYETLERRYANERDKAQFLSQELEHAKMELAKYKL--------AEKTESSHE-QWLFRRLQEEEAKSGHL 713
Cdd:PRK04778 395 IEKEQEKLSEMLQGLRKDELEAREKLERYRNKLHEIKRYLEKSNLpglpedylEMFFEVSDEiEALAEELEEKPINMEAV 474
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 295424207 714 SREVDALKEKIHE-YMATEDLIchlqgDHSLLQKKLNQQENRNRDLGREIEN-LTKELERYRHF 775
Cdd:PRK04778 475 NRLLEEATEDVETlEEETEELV-----ENATLTEQLIQYANRYRSDNEEVAEaLNEAERLFREY 533
|
|
| PRK05771 |
PRK05771 |
V-type ATP synthase subunit I; Validated |
314-550 |
4.99e-04 |
|
V-type ATP synthase subunit I; Validated
Pssm-ID: 235600 [Multi-domain] Cd Length: 646 Bit Score: 44.15 E-value: 4.99e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 314 EDSQNRQLRQKLAALSRQIDELEETNRSLRKAEEELQDIKDKinKGEYGNSGIMDEVDELRKRVLDMEGKDEELIKMEEQ 393
Cdd:PRK05771 41 SNERLRKLRSLLTKLSEALDKLRSYLPKLNPLREEKKKVSVK--SLEELIKDVEEELEKIEKEIKELEEEISELENEIKE 118
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 394 CRDLNKRLEKetvqSKDFKLEVDKL-----------SVRITALEKLEDALDKSKQECYS--------------------- 441
Cdd:PRK05771 119 LEQEIERLEP----WGNFDLDLSLLlgfkyvsvfvgTVPEDKLEELKLESDVENVEYIStdkgyvyvvvvvlkelsdeve 194
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 442 ---LKCNLEKEKM-TTKQLSEELESLNARIKELEAIESRLEKTEITLKDDLTKLKTLTVMLVD---ERKTMSEKLKQTEd 514
Cdd:PRK05771 195 eelKKLGFERLELeEEGTPSELIREIKEELEEIEKERESLLEELKELAKKYLEELLALYEYLEielERAEALSKFLKTD- 273
|
250 260 270
....*....|....*....|....*....|....*.
gi 295424207 515 klqsTTSQLQAeqnkvtTVTEKLIEETKRALKSKTD 550
Cdd:PRK05771 274 ----KTFAIEG------WVPEDRVKKLKELIDKATG 299
|
|
| Cast |
pfam10174 |
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part ... |
271-684 |
6.64e-04 |
|
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part of the CAZ (cytomatrix at the active zone) complex which is involved in determining the site of synaptic vesicle fusion. The C-terminus is a PDZ-binding motif that binds directly to RIM (a small G protein Rab-3A effector). The family also contains four coiled-coil domains.
Pssm-ID: 431111 [Multi-domain] Cd Length: 766 Bit Score: 44.04 E-value: 6.64e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 271 KLALAEARAQEEEQKATRLEKELQTQTTEFHQNQdkimaKLTNEDSQNRQLRQKLAALSRQIDELEetnRSLRKAEEELQ 350
Cdd:pfam10174 186 RIAEAEMQLGHLEVLLDQKEKENIHLREELHRRN-----QLQPDPAKTKALQTVIEMKDTKISSLE---RNIRDLEDEVQ 257
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 351 DIKDKINKGEYGNSGIMDEVDELRKRVLDMEGK----DEELIKMEEQCRDLNKRLEKETVQSKDFKLEVDKLSVRITALE 426
Cdd:pfam10174 258 MLKTNGLLHTEDREEEIKQMEVYKSHSKFMKNKidqlKQELSKKESELLALQTKLETLTNQNSDCKQHIEVLKESLTAKE 337
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 427 KLEDALdksKQECYSLKCNL-EKEKM---TTKQLSEELESLNARIKELEAIESRLEKTEITLKDDLTKLKTLTVMLVDER 502
Cdd:pfam10174 338 QRAAIL---QTEVDALRLRLeEKESFlnkKTKQLQDLTEEKSTLAGEIRDLKDMLDVKERKINVLQKKIENLQEQLRDKD 414
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 503 KTMSEkLKQTEDKLQSTTSQlqaEQNKVTTVTEKLIEETK--RALKSKTDAEEKMYsvTKERDDLRNKLKaeeekghDLL 580
Cdd:pfam10174 415 KQLAG-LKERVKSLQTDSSN---TDTALTTLEEALSEKERiiERLKEQREREDRER--LEELESLKKENK-------DLK 481
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 581 SKVTILKNRLQSLEAIEKDFVKNKLNQDSSKStaalhQENNKIKELSQEVENlklKLKDMKAIEDDLMKTEdEYETLERR 660
Cdd:pfam10174 482 EKVSALQPELTEKESSLIDLKEHASSLASSGL-----KKDSKLKSLEIAVEQ---KKEECSKLENQLKKAH-NAEEAVRT 552
|
410 420
....*....|....*....|....
gi 295424207 661 YANERDKAQFLSQELEHAKMELAK 684
Cdd:pfam10174 553 NPEINDRIRLLEQEVARYKEESGK 576
|
|
| PRK12704 |
PRK12704 |
phosphodiesterase; Provisional |
342-491 |
7.96e-04 |
|
phosphodiesterase; Provisional
Pssm-ID: 237177 [Multi-domain] Cd Length: 520 Bit Score: 43.23 E-value: 7.96e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 342 LRKAEEELQDIKDKINKgeygnsgimdEVDELRKRVLdMEGKDEELIKMEEQCRDLNKRLEKETVQSKDFKLEVDKLSVR 421
Cdd:PRK12704 33 IKEAEEEAKRILEEAKK----------EAEAIKKEAL-LEAKEEIHKLRNEFEKELRERRNELQKLEKRLLQKEENLDRK 101
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 295424207 422 ITALEKLEDALDKSKQECYSLKCNLEK-----EKMTTKQLsEELESLNARIKElEAIESRLEKTEITLKDDLTKL 491
Cdd:PRK12704 102 LELLEKREEELEKKEKELEQKQQELEKkeeelEELIEEQL-QELERISGLTAE-EAKEILLEKVEEEARHEAAVL 174
|
|
| GumC |
COG3206 |
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis]; |
222-393 |
1.16e-03 |
|
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 442439 [Multi-domain] Cd Length: 687 Bit Score: 43.08 E-value: 1.16e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 222 RIKTLKEE--LTKLKSFALMVVDEQQRLTAQLALQRQKIQALTTSAKETQGKLALAEARAQEEEQKAT--RLEKELQTQT 297
Cdd:COG3206 197 ALEEFRQKngLVDLSEEAKLLLQQLSELESQLAEARAELAEAEARLAALRAQLGSGPDALPELLQSPViqQLRAQLAELE 276
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 298 TEfhqnQDKIMAKLTNEDSQNRQLRQKLAALSRQIDelEETNRSLRKAEEELQDIKDKINKgeygnsgIMDEVDELRKRV 377
Cdd:COG3206 277 AE----LAELSARYTPNHPDVIALRAQIAALRAQLQ--QEAQRILASLEAELEALQAREAS-------LQAQLAQLEARL 343
|
170
....*....|....*.
gi 295424207 378 LDMEGKDEELIKMEEQ 393
Cdd:COG3206 344 AELPELEAELRRLERE 359
|
|
| sbcc |
TIGR00618 |
exonuclease SbcC; All proteins in this family for which functions are known are part of an ... |
266-817 |
1.31e-03 |
|
exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 43.03 E-value: 1.31e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 266 KETQGKLALAEARAQEEEQkatrLEKELQTQTTEFHQNQDKIMAKLTNEdsqNRQLRQKLAALSRQIDELEETNRSLRKA 345
Cdd:TIGR00618 190 KSLHGKAELLTLRSQLLTL----CTPCMPDTYHERKQVLEKELKHLREA---LQQTQQSHAYLTQKREAQEEQLKKQQLL 262
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 346 EEELQDIKDKINkgEYGNSGIMDEVDELRKRVLDMEGKDEELIKMEEQCRDLNKRL-EKETVQSKDFKLEVDKLSVRiTA 424
Cdd:TIGR00618 263 KQLRARIEELRA--QEAVLEETQERINRARKAAPLAAHIKAVTQIEQQAQRIHTELqSKMRSRAKLLMKRAAHVKQQ-SS 339
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 425 LEKLEDALDKSKQECYSLKCNLEKEKMTTKQLSEELEsLNARIKELEAIESRLEKTEITLKDDLTKLKTLtVMLVDERKT 504
Cdd:TIGR00618 340 IEEQRRLLQTLHSQEIHIRDAHEVATSIREISCQQHT-LTQHIHTLQQQKTTLTQKLQSLCKELDILQRE-QATIDTRTS 417
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 505 MSEKLKQtedKLQSTTSQLQAEQnKVTTVTEKLIEETKRALKSKTDAEEKMYSVTKERD----DLRNKLKAEEEKGhdll 580
Cdd:TIGR00618 418 AFRDLQG---QLAHAKKQQELQQ-RYAELCAAAITCTAQCEKLEKIHLQESAQSLKEREqqlqTKEQIHLQETRKK---- 489
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 581 skvTILKNRLQSLEAIEKDFvknklnqdsSKSTAALHQEnnkikelSQEVENLKLKLKDMKAIEDDLMKTEDEYETLERR 660
Cdd:TIGR00618 490 ---AVVLARLLELQEEPCPL---------CGSCIHPNPA-------RQDIDNPGPLTRRMQRGEQTYAQLETSEEDVYHQ 550
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 661 YANERDKAQFLSQELEHAKMELAkyKLAEKTESSHE-------------QWLFRRLQEEEAKSGHLSREVDALKEKIHEY 727
Cdd:TIGR00618 551 LTSERKQRASLKEQMQEIQQSFS--ILTQCDNRSKEdipnlqnitvrlqDLTEKLSEAEDMLACEQHALLRKLQPEQDLQ 628
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 728 mateDLICHLQGDHSLLQKKLNQqenrnrdLGREIENLTKELERYRHF-SKSLRPSLNERRISDPQVFSKEVQTEAADSE 806
Cdd:TIGR00618 629 ----DVRLHLQQCSQELALKLTA-------LHALQLTLTQERVREHALsIRVLPKELLASRQLALQKMQSEKEQLTYWKE 697
|
570
....*....|.
gi 295424207 807 PPDYKSLIPLE 817
Cdd:TIGR00618 698 MLAQCQTLLRE 708
|
|
| DR0291 |
COG1579 |
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ... |
369-555 |
1.31e-03 |
|
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];
Pssm-ID: 441187 [Multi-domain] Cd Length: 236 Bit Score: 41.83 E-value: 1.31e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 369 EVDELRKRVLDMEgkdEELIKMEEQCRDLNKRLEKETVQSKDFKLEVDKLSvriTALEKLEDALDKSKqecyslkcnlek 448
Cdd:COG1579 18 ELDRLEHRLKELP---AELAELEDELAALEARLEAAKTELEDLEKEIKRLE---LEIEEVEARIKKYE------------ 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 449 EKMTTKQLSEELESLNariKELEAIESRLEKTEITLKDdltklktltvmLVDERKTMSEKLKQTEDKLQSTTSQLQAEQN 528
Cdd:COG1579 80 EQLGNVRNNKEYEALQ---KEIESLKRRISDLEDEILE-----------LMERIEELEEELAELEAELAELEAELEEKKA 145
|
170 180
....*....|....*....|....*..
gi 295424207 529 KVTTVTEKLIEETKRALKSKTDAEEKM 555
Cdd:COG1579 146 ELDEELAELEAELEELEAEREELAAKI 172
|
|
| 235kDa-fam |
TIGR01612 |
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ... |
280-644 |
1.41e-03 |
|
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.
Pssm-ID: 130673 [Multi-domain] Cd Length: 2757 Bit Score: 43.12 E-value: 1.41e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 280 QEEEQKATRLEKELQTQTTEFHQNQD--KIMAKLTNEDSQNRQLRQKLaalsRQIDELEETNRSLR-KAEEELQDIKDKI 356
Cdd:TIGR01612 1946 EKEPEIYTKIRDSYDTLLDIFKKSQDlhKKEQDTLNIIFENQQLYEKI----QASNELKDTLSDLKyKKEKILNDVKLLL 2021
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 357 NKgeygnsgimdeVDELRKRVLDMEGKDEEL-IKMEEQCRDLNKRLEKET---VQSKDFKLEVDKLSVRITALEKLEDAL 432
Cdd:TIGR01612 2022 HK-----------FDELNKLSCDSQNYDTILeLSKQDKIKEKIDNYEKEKekfGIDFDVKAMEEKFDNDIKDIEKFENNY 2090
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 433 DKSKQECYSLKCNLEKEKMTTKQLSEELESLNARIKELEaiESRLEKTEitLKDDLTKLKTLTVMLvdERKTMSEKLKQT 512
Cdd:TIGR01612 2091 KHSEKDNHDFSEEKDNIIQSKKKLKELTEAFNTEIKIIE--DKIIEKND--LIDKLIEMRKECLLF--SYATLVETLKSK 2164
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 513 edklQSTTSQLQAEQNKVTTVTEKLIEETKRALKSKTDAEEKMYSVTKERDDLRNKLKAEEEKGHDLLSKVtilKNRLQS 592
Cdd:TIGR01612 2165 ----VINHSEFITSAAKFSKDFFEFIEDISDSLNDDIDALQIKYNLNQTKKHMISILADATKDHNNLIEKE---KEATKI 2237
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*.
gi 295424207 593 LEAIEKDFVKNKLNQDSSkstaALHQENNKI----KELSQEVENLKLKLKDMKAIE 644
Cdd:TIGR01612 2238 INNLTELFTIDFNNADAD----ILHNNKIQIiyfnSELHKSIESIKKLYKKINAFK 2289
|
|
| mukB |
PRK04863 |
chromosome partition protein MukB; |
222-607 |
1.54e-03 |
|
chromosome partition protein MukB;
Pssm-ID: 235316 [Multi-domain] Cd Length: 1486 Bit Score: 43.02 E-value: 1.54e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 222 RIKTLKEELtklksfalmvvDEQQRLTAQLALQRQKIQALTTSAKETQGK-LALAEARAQEEEQKATRleKELQTQTTEf 300
Cdd:PRK04863 787 RIEQLRAER-----------EELAERYATLSFDVQKLQRLHQAFSRFIGShLAVAFEADPEAELRQLN--RRRVELERA- 852
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 301 hqnqdkimakLTNEDSQNRQLRQKLAALSRQIDELEETNRSLRKAEEElqdikdkinkgeygnsGIMDEVDELRkrvldm 380
Cdd:PRK04863 853 ----------LADHESQEQQQRSQLEQAKEGLSALNRLLPRLNLLADE----------------TLADRVEEIR------ 900
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 381 egkdEELIKMEEQCRDLNK------RLEKE--TVQSKDFKLEVDKLSVritalEKLEDALDKSKQECYSLKCNLEK---- 448
Cdd:PRK04863 901 ----EQLDEAEEAKRFVQQhgnalaQLEPIvsVLQSDPEQFEQLKQDY-----QQAQQTQRDAKQQAFALTEVVQRrahf 971
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 449 -----EKMTTKQlSEELESLNARIKELEAIESRLEKTEITLKDDLTKLKTLTVMLVDERKTMSEKLKQTEDKLQSTTSQL 523
Cdd:PRK04863 972 syedaAEMLAKN-SDLNEKLRQRLEQAEQERTRAREQLRQAQAQLAQYNQVLASLKSSYDAKRQMLQELKQELQDLGVPA 1050
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 524 QAEQNKVTTVTEKLIEETKRALKSKTDAEEKMYSVTK-ERDDLRNKLKAEEEKGHDLLSKVTILKNRLQS-LEAIEKDFV 601
Cdd:PRK04863 1051 DSGAEERARARRDELHARLSANRSRRNQLEKQLTFCEaEMDNLTKKLRKLERDYHEMREQVVNAKAGWCAvLRLVKDNGV 1130
|
....*.
gi 295424207 602 KNKLNQ 607
Cdd:PRK04863 1131 ERRLHR 1136
|
|
| HOOK |
pfam05622 |
HOOK protein coiled-coil region; This family consists of several HOOK1, 2 and 3 proteins from ... |
280-608 |
1.55e-03 |
|
HOOK protein coiled-coil region; This family consists of several HOOK1, 2 and 3 proteins from different eukaryotic organizms. The different members of the human gene family are HOOK1, HOOK2 and HOOK3. Different domains have been identified in the three human HOOK proteins, and it was demonstrated that the highly conserved NH2-domain mediates attachment to microtubules, whereas this central coiled-coil motif mediates homodimerization and the more divergent C-terminal domains are involved in binding to specific organelles (organelle-binding domains). It has been demonstrated that endogenous HOOK3 binds to Golgi membranes, whereas both HOOK1 and HOOK2 are localized to discrete but unidentified cellular structures. In mice the Hook1 gene is predominantly expressed in the testis. Hook1 function is necessary for the correct positioning of microtubular structures within the haploid germ cell. Disruption of Hook1 function in mice causes abnormal sperm head shape and fragile attachment of the flagellum to the sperm head. This entry includes the central coiled-coiled domain and the divergent C-terminal domain.
Pssm-ID: 461694 [Multi-domain] Cd Length: 528 Bit Score: 42.37 E-value: 1.55e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 280 QEEEQKATRLEKELQT---QTTEFHQNQDKIMAKLTNEDSQNRQLRQKLAALSRQIDELEETNRSLRKAEEEL---QDIK 353
Cdd:pfam05622 172 EEELKKANALRGQLETykrQVQELHGKLSEESKKADKLEFEYKKLEEKLEALQKEKERLIIERDTLRETNEELrcaQLQQ 251
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 354 DKINKGEYGNSGIMDEVDELRKRVLDMEGKdEELIKMEEQcrdlNKRL-EKETVQSKDfklevdklsvRITALEKLedal 432
Cdd:pfam05622 252 AELSQADALLSPSSDPGDNLAAEIMPAEIR-EKLIRLQHE----NKMLrLGQEGSYRE----------RLTELQQL---- 312
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 433 dkskqecyslkcnLEKEKMTTKQLSEELESLNARIKELEAiesRLEKTEITLKDDLTKLKTlTVMLVDERKTMSEKLKQT 512
Cdd:pfam05622 313 -------------LEDANRRKNELETQNRLANQRILELQQ---QVEELQKALQEQGSKAED-SSLLKQKLEEHLEKLHEA 375
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 513 EDKLQSTTSQLQAEQNKVTTVTEKLIEETKRALKSKTD----AEE--KMY-----SVTKERDDLRNKLKAEEekghdlls 581
Cdd:pfam05622 376 QSELQKKKEQIEELEPKQDSNLAQKIDELQEALRKKDEdmkaMEEryKKYvekakSVIKTLDPKQNPASPPE-------- 447
|
330 340 350
....*....|....*....|....*....|.
gi 295424207 582 kVTILKNRLQ----SLEAIEKDFVKNKLNQD 608
Cdd:pfam05622 448 -IQALKNQLLekdkKIEHLERDFEKSKLQRE 477
|
|
| FPP |
pfam05911 |
Filament-like plant protein, long coiled-coil; FPP is a family of long coiled-coil plant ... |
305-574 |
1.81e-03 |
|
Filament-like plant protein, long coiled-coil; FPP is a family of long coiled-coil plant proteins that are filament-like. It interacts with the nuclear envelope-associated protein, MAF1, the WPP family pfam13943.
Pssm-ID: 461778 [Multi-domain] Cd Length: 859 Bit Score: 42.35 E-value: 1.81e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 305 DKIMAKLTNEDSQNRQLRQKLAALSRQIDELEETNRSLRKAEEELqdikdkinkgeygnSGIMDEVDELRKRVLDMEGKD 384
Cdd:pfam05911 562 SKEALDDQDTSSDSSELSEVLQQFSATCNDVLSGKADLEDFVLEL--------------SHILDWISNHCFSLLDVSSME 627
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 385 EELIKMEeqCRDLNKRLEKETVQSKDFKLEVDKLS--VRITALEKLEDALDKSKQ-ECYSLKCNLEKEKMTTKQLSEELE 461
Cdd:pfam05911 628 DEIKKHD--CIDKVTLSENKVAQVDNGCSEIDNLSsdPEIPSDGPLVSGSNDLKTeENKRLKEEFEQLKSEKENLEVELA 705
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 462 SLNARIKELEAIESRLEKTEITLKDDLTKLKTLTVMLVDERKTMSEKLKQTEDKLQSTTSQLQAEQNKVTTVTEKLIEET 541
Cdd:pfam05911 706 SCTENLESTKSQLQESEQLIAELRSELASLKESNSLAETQLKCMAESYEDLETRLTELEAELNELRQKFEALEVELEEEK 785
|
250 260 270 280
....*....|....*....|....*....|....*....|..
gi 295424207 542 K---RALKSKTDAEEKMYSVTKER------DDLRNKLKAEEE 574
Cdd:pfam05911 786 NcheELEAKCLELQEQLERNEKKEssncdaDQEDKKLQQEKE 827
|
|
| 235kDa-fam |
TIGR01612 |
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ... |
289-655 |
1.87e-03 |
|
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.
Pssm-ID: 130673 [Multi-domain] Cd Length: 2757 Bit Score: 42.73 E-value: 1.87e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 289 LEKELQTQTTEFHQNQDKIMAKLTNEDSQNRQ-----LRQKLAALSRQ--IDELEETNRslrkaeeeLQDIKDKINKgEY 361
Cdd:TIGR01612 639 LAKISPYQVPEHLKNKDKIYSTIKSELSKIYEddidaLYNELSSIVKEnaIDNTEDKAK--------LDDLKSKIDK-EY 709
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 362 GNSGIMdEVDELRKRVLDMEGKDEELIKM---------EEQCRDLNKRLEketvqskDFKLEVDKLSVRITALEKLEDAL 432
Cdd:TIGR01612 710 DKIQNM-ETATVELHLSNIENKKNELLDIiveikkhihGEINKDLNKILE-------DFKNKEKELSNKINDYAKEKDEL 781
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 433 DKSKQECYSLKC------------------NLEKEKMTTKQLSEELESLNARIKELEaiesrlekteiTLKDDLTKLKTL 494
Cdd:TIGR01612 782 NKYKSKISEIKNhyndqinidnikdedakqNYDKSKEYIKTISIKEDEIFKIINEMK-----------FMKDDFLNKVDK 850
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 495 TVMLVDERKtmsEKLKQTEDKLQSTTSQLQAE-QNKVTTVTEKLIEETKRALKSKTDAEEKMY---SVTKERDDLRNKLK 570
Cdd:TIGR01612 851 FINFENNCK---EKIDSEHEQFAELTNKIKAEiSDDKLNDYEKKFNDSKSLINEINKSIEEEYqniNTLKKVDEYIKICE 927
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 571 AEEEKGHDLLSKVTILKNRL-------QSLEAIEKDF-------VKNKLNQ-DSSKSTAALHQENNKIKELSQEVENLKL 635
Cdd:TIGR01612 928 NTKESIEKFHNKQNILKEILnknidtiKESNLIEKSYkdkfdntLIDKINElDKAFKDASLNDYEAKNNELIKYFNDLKA 1007
|
410 420
....*....|....*....|
gi 295424207 636 KLKDMKaiEDDLMKTEDEYE 655
Cdd:TIGR01612 1008 NLGKNK--ENMLYHQFDEKE 1025
|
|
| CALCOCO1 |
pfam07888 |
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ... |
398-738 |
2.15e-03 |
|
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.
Pssm-ID: 462303 [Multi-domain] Cd Length: 488 Bit Score: 41.80 E-value: 2.15e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 398 NKRLEKETVQSKDFKLEVDKLSVRITA-LEKLEDALDKSKQECYSLKCNLEKEKMTTKQLSEELESL-------NARIKE 469
Cdd:pfam07888 54 NRQREKEKERYKRDREQWERQRRELESrVAELKEELRQSREKHEELEEKYKELSASSEELSEEKDALlaqraahEARIRE 133
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 470 LEAIESRLEKTEITLKDDLTKLKTLTVMLV-------DERKTMSEKLKQTEDKLQSTTSQLQ------AEQNKVTTVTEK 536
Cdd:pfam07888 134 LEEDIKTLTQRVLERETELERMKERAKKAGaqrkeeeAERKQLQAKLQQTEEELRSLSKEFQelrnslAQRDTQVLQLQD 213
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 537 LIEETKRALKSKTDAEEKMYSVTKERDDLRNKLKAEEEkghdllsKVTILKNRLQSLEAIEkdfvknklnqdsSKSTAAL 616
Cdd:pfam07888 214 TITTLTQKLTTAHRKEAENEALLEELRSLQERLNASER-------KVEGLGEELSSMAAQR------------DRTQAEL 274
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 617 HQENNKIKELSQEVENLKLKLKDMKAieddlmKTEDEYETLERRYANERDKAQFLSQEL---------EHAKMELAKYKL 687
Cdd:pfam07888 275 HQARLQAAQLTLQLADASLALREGRA------RWAQERETLQQSAEADKDRIEKLSAELqrleerlqeERMEREKLEVEL 348
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|...
gi 295424207 688 AEKTESSHEQW--LFRRLQEEEAKSGHLSREVDALKEKIHEYMateDLICHLQ 738
Cdd:pfam07888 349 GREKDCNRVQLseSRRELQELKASLRVAQKEKEQLQAEKQELL---EYIRQLE 398
|
|
| COG2433 |
COG2433 |
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only]; |
282-418 |
2.45e-03 |
|
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
Pssm-ID: 441980 [Multi-domain] Cd Length: 644 Bit Score: 41.77 E-value: 2.45e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 282 EEQKATRLEKELQTQTTEFHQNQdkimAKLTNEDSQNRQLRQKLAALSRQIDELEETNRSLRKAEEELQdikdkinkgey 361
Cdd:COG2433 383 EELIEKELPEEEPEAEREKEHEE----RELTEEEEEIRRLEEQVERLEAEVEELEAELEEKDERIERLE----------- 447
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*..
gi 295424207 362 gnsgimDEVDELRKRVLDMEGKDEELIKMEEQCRDLNKRLEKETVQSKDFKLEVDKL 418
Cdd:COG2433 448 ------RELSEARSEERREIRKDREISRLDREIERLERELEEERERIEELKRKLERL 498
|
|
| GumC |
COG3206 |
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis]; |
244-437 |
2.49e-03 |
|
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 442439 [Multi-domain] Cd Length: 687 Bit Score: 41.93 E-value: 2.49e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 244 QQRL-TAQLALQ--RQKIQALTTSAKETQGKLALAEARAQEEEQKATRLEKELQTQTTEFHQNQDKIMAKLTNEDSQNRQ 320
Cdd:COG3206 188 RKELeEAEAALEefRQKNGLVDLSEEAKLLLQQLSELESQLAEARAELAEAEARLAALRAQLGSGPDALPELLQSPVIQQ 267
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 321 LRQKLAALSRQIDELE----ETNRSLRKAEEELQDIKDKINKgeygnsGIMDEVDELRKRVLDMEGKDEELIKMEEQCRD 396
Cdd:COG3206 268 LRAQLAELEAELAELSarytPNHPDVIALRAQIAALRAQLQQ------EAQRILASLEAELEALQAREASLQAQLAQLEA 341
|
170 180 190 200
....*....|....*....|....*....|....*....|.
gi 295424207 397 LNKRLEKETVQSKDFKLEVDklsvriTALEKLEDALDKSKQ 437
Cdd:COG3206 342 RLAELPELEAELRRLEREVE------VARELYESLLQRLEE 376
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
539-842 |
2.62e-03 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 41.97 E-value: 2.62e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 539 EETKRALKSKTDAEEKMYSVTKERDDLRNKLKAEEEKGHDLLSKVTILKNRLQSLEAIEKDFVKNKLnqdsskstaalHQ 618
Cdd:TIGR02168 175 KETERKLERTRENLDRLEDILNELERQLKSLERQAEKAERYKELKAELRELELALLVLRLEELREEL-----------EE 243
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 619 ENNKIKELSQEVENLKLKLKdmkAIEDDLMKTEDEYETLERRYANERDKAQFLSQELEHAKMELAKYKLAEKTESSHEQW 698
Cdd:TIGR02168 244 LQEELKEAEEELEELTAELQ---ELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEE 320
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 699 LFRRLQEEEAKSGHLSREVDALKEKIHEYMATEDLichLQGDHSLLQKKLNQQENRNRDLGREIENLTKELERYRHFSKS 778
Cdd:TIGR02168 321 LEAQLEELESKLDELAEELAELEEKLEELKEELES---LEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIAS 397
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 295424207 779 LRpslNERRISDPQVFSKEVQTEAADSEPPD-YKSLIPLERAVINGQFYEENEDQDDDPNEEESV 842
Cdd:TIGR02168 398 LN---NEIERLEARLERLEDRRERLQQEIEElLKKLEEAELKELQAELEELEEELEELQEELERL 459
|
|
| PRK09039 |
PRK09039 |
peptidoglycan -binding protein; |
245-375 |
2.93e-03 |
|
peptidoglycan -binding protein;
Pssm-ID: 181619 [Multi-domain] Cd Length: 343 Bit Score: 41.10 E-value: 2.93e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 245 QRLTAQLALQRQKIQALTTSAKETQGKLALAEA--------------RAQEEEQKATRLEKELQTQTTEFHQNQDKImaK 310
Cdd:PRK09039 63 AELADLLSLERQGNQDLQDSVANLRASLSAAEAersrlqallaelagAGAAAEGRAGELAQELDSEKQVSARALAQV--E 140
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 295424207 311 LTNEdsQNRQLRQKLAALSRQIDELEETNRSlrkAEEELQDIkdkinkGEYGNSGIMDEVDELRK 375
Cdd:PRK09039 141 LLNQ--QIAALRRQLAALEAALDASEKRDRE---SQAKIADL------GRRLNVALAQRVQELNR 194
|
|
| rad50 |
TIGR00606 |
rad50; All proteins in this family for which functions are known are involvedin recombination, ... |
391-783 |
3.16e-03 |
|
rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).
Pssm-ID: 129694 [Multi-domain] Cd Length: 1311 Bit Score: 41.96 E-value: 3.16e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 391 EEQCRDLNKRLEKETVQSKDFKLEVDKLSVRITALEKLEDALDKSKQECYSLKCNLEKEKMTTKQLSEEleslnarikEL 470
Cdd:TIGR00606 233 LESSREIVKSYENELDPLKNRLKEIEHNLSKIMKLDNEIKALKSRKKQMEKDNSELELKMEKVFQGTDE---------QL 303
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 471 EAIESRLEKTEITLKDDLTKLKTLTVMLVDERKTMSEKlkQTEDKLQSTTSQLQAEQNKVTTVTEKLiEETKRALKSKTD 550
Cdd:TIGR00606 304 NDLYHNHQRTVREKERELVDCQRELEKLNKERRLLNQE--KTELLVEQGRLQLQADRHQEHIRARDS-LIQSLATRLELD 380
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 551 AEEKMYSVTKERDDLRNKLKAEEEKGHDLLSKVT---ILKNRLQSLEAIEKDFVKNKLNQDSSKSTAALHQENNKIKELS 627
Cdd:TIGR00606 381 GFERGPFSERQIKNFHTLVIERQEDEAKTAAQLCadlQSKERLKQEQADEIRDEKKGLGRTIELKKEILEKKQEELKFVI 460
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 628 QEVENLKLKLKDMKAIEDDLMKTEDEYETLERRYANERDKAQFLSQELEHAKMELAKYKLAEKTESSHEQWLFRRLQEEE 707
Cdd:TIGR00606 461 KELQQLEGSSDRILELDQELRKAERELSKAEKNSLTETLKKEVKSLQNEKADLDRKLRKLDQEMEQLNHHTTTRTQMEML 540
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 708 AKS---------GHLSREVDALKEKIHEYMATEDLICHLQGdhslLQKKLNQQENRNRDLGREIENLTKELERYRHFSKS 778
Cdd:TIGR00606 541 TKDkmdkdeqirKIKSRHSDELTSLLGYFPNKKQLEDWLHS----KSKEINQTRDRLAKLNKELASLEQNKNHINNELES 616
|
....*
gi 295424207 779 LRPSL 783
Cdd:TIGR00606 617 KEEQL 621
|
|
| PspA_IM30 |
pfam04012 |
PspA/IM30 family; This family includes PspA a protein that suppresses sigma54-dependent ... |
190-381 |
3.30e-03 |
|
PspA/IM30 family; This family includes PspA a protein that suppresses sigma54-dependent transcription. The PspA protein, a negative regulator of the Escherichia coli phage shock psp operon, is produced when virulence factors are exported through secretins in many Gram-negative pathogenic bacteria and its homolog in plants, VIPP1, plays a critical role in thylakoid biogenesis, essential for photosynthesis. Activation of transcription by the enhancer-dependent bacterial sigma(54) containing RNA polymerase occurs through ATP hydrolysis-driven protein conformational changes enabled by activator proteins that belong to the large AAA(+) mechanochemical protein family. It has been shown that PspA directly and specifically acts upon and binds to the AAA(+) domain of the PspF transcription activator.
Pssm-ID: 461130 [Multi-domain] Cd Length: 215 Bit Score: 40.43 E-value: 3.30e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 190 FINLLEQECERLKKLIDQEtasqekkeqekekrIKTLKEELTKLKSFALMVVDEQQRLTAQLALQRQKIQALTTSAKE-- 267
Cdd:pfam04012 12 NIHEGLDKAEDPEKMLEQA--------------IRDMQSELVKARQALAQTIARQKQLERRLEQQTEQAKKLEEKAQAal 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 268 TQGKLALAEArAQEEEQKATRLEKELQTQTTEFHqnqdkimakltnedSQNRQLRQKLAALSRQIDELEETNRSLrKAEE 347
Cdd:pfam04012 78 TKGNEELARE-ALAEKKSLEKQAEALETQLAQQR--------------SAVEQLRKQLAALETKIQQLKAKKNLL-KARL 141
|
170 180 190
....*....|....*....|....*....|....*.
gi 295424207 348 ELQDIKDKINK--GEYGNSGIMDEVDELRKRVLDME 381
Cdd:pfam04012 142 KAAKAQEAVQTslGSLSTSSATDSFERIEEKIEERE 177
|
|
| CCDC158 |
pfam15921 |
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ... |
77-348 |
3.78e-03 |
|
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.
Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 41.64 E-value: 3.78e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 77 LEGELQARDEVIGILRAEKIDLALLEAQYGFVTpkkvlealqrDAFQAKSAPWQEDIYEKPMNELD-KVVEKHKESHRRI 155
Cdd:pfam15921 553 LKLQMAEKDKVIEILRQQIENMTQLVGQHGRTA----------GAMQVEKAQLEKEINDRRLELQEfKILKDKKDAKIRE 622
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 156 LE-----------QLLMVERSHRQTIMEMEEEKRKHKEYMKKSDEFINLLEQECERLKKLIDQETASQEKKEQEKEKRIK 224
Cdd:pfam15921 623 LEarvsdlelekvKLVNAGSERLRAVKDIKQERDQLLNEVKTSRNELNSLSEDYEVLKRNFRNKSEEMETTTNKLKMQLK 702
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 225 TLKEELTK----LKSF------ALMVVDEQQRltaQLALQRQKIQALTTSAKETQGKLALAEARAQEEEQKATRLEKELQ 294
Cdd:pfam15921 703 SAQSELEQtrntLKSMegsdghAMKVAMGMQK---QITAKRGQIDALQSKIQFLEEAMTNANKEKHFLKEEKNKLSQELS 779
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*...
gi 295424207 295 TQTTEfhqnQDKIMAKLTNEDSQNRQLRQKLAALSRQID----ELEETNRSLRKAEEE 348
Cdd:pfam15921 780 TVATE----KNKMAGELEVLRSQERRLKEKVANMEVALDkaslQFAECQDIIQRQEQE 833
|
|
| DR0291 |
COG1579 |
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ... |
222-358 |
3.80e-03 |
|
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];
Pssm-ID: 441187 [Multi-domain] Cd Length: 236 Bit Score: 40.29 E-value: 3.80e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 222 RIKTLKEELTKLKsfalmvvDEQQRLTAQLALQRQKIQALTTSAKETQGKLALAEARAQEEEQK---------ATRLEKE 292
Cdd:COG1579 25 RLKELPAELAELE-------DELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEQlgnvrnnkeYEALQKE 97
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 295424207 293 LQTQTTEFHQNQDKIMAKLTNEDSQNRQLRQKLAALSRQIDELEETNRSLRKAEEELQDIKDKINK 358
Cdd:COG1579 98 IESLKRRISDLEDEILELMERIEELEEELAELEAELAELEAELEEKKAELDEELAELEAELEELEA 163
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
319-568 |
4.39e-03 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 41.44 E-value: 4.39e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 319 RQLRQKLAALSRQIDELEETNRSLRKAEEE---LQDIKDKINKGEyGNSGIMDEVDELRKRvLDMEGKDEELIKMEEQCR 395
Cdd:COG4913 221 PDTFEAADALVEHFDDLERAHEALEDAREQielLEPIRELAERYA-AARERLAELEYLRAA-LRLWFAQRRLELLEAELE 298
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 396 DLNKRLEKETVQSKDFKLEVDKLSVRitaLEKLEDALDKSKQEcyslkcNLEkekmttkQLSEELESLNARIKELEAIES 475
Cdd:COG4913 299 ELRAELARLEAELERLEARLDALREE---LDELEAQIRGNGGD------RLE-------QLEREIERLERELEERERRRA 362
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 476 RLEKTeitlkddltkLKTLTVMLVDERKTMSEKLKQTEDKLQSTTSQLQAEQNKVTtvteklieetkRALKSKTDAEEKM 555
Cdd:COG4913 363 RLEAL----------LAALGLPLPASAEEFAALRAEAAALLEALEEELEALEEALA-----------EAEAALRDLRREL 421
|
250
....*....|...
gi 295424207 556 YSVTKERDDLRNK 568
Cdd:COG4913 422 RELEAEIASLERR 434
|
|
| Myosin_tail_1 |
pfam01576 |
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ... |
461-770 |
4.61e-03 |
|
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.
Pssm-ID: 460256 [Multi-domain] Cd Length: 1081 Bit Score: 41.31 E-value: 4.61e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 461 ESLNARIKELEAIESRLEKTEITLKDDLTKLKTLTvmlvDERKTMSEKLkQTEDKLQSTTSQLQAEQNKVTTVTEKLIEE 540
Cdd:pfam01576 5 EEMQAKEEELQKVKERQQKAESELKELEKKHQQLC----EEKNALQEQL-QAETELCAEAEEMRARLAARKQELEEILHE 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 541 TKRALKSKTDAEEKMYSVTKERD----DLRNKLKAEEEKGHDL-LSKVTI------LKNRLQSLEAIEKDFVKNK--LNQ 607
Cdd:pfam01576 80 LESRLEEEEERSQQLQNEKKKMQqhiqDLEEQLDEEEAARQKLqLEKVTTeakikkLEEDILLLEDQNSKLSKERklLEE 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 608 DSSKSTAALHQENNKIKELSQevenLKLKLKDMKAIEDDLMKTED----EYETLERRYANERDKAQFLSQELEhAKMELA 683
Cdd:pfam01576 160 RISEFTSNLAEEEEKAKSLSK----LKNKHEAMISDLEERLKKEEkgrqELEKAKRKLEGESTDLQEQIAELQ-AQIAEL 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 684 KYKLAEKTESSheQWLFRRLQEEEAKSGHLSREVDALKEKIHEymatedlichLQGDHSLLQKKLNQQENRNRDLGREIE 763
Cdd:pfam01576 235 RAQLAKKEEEL--QAALARLEEETAQKNNALKKIRELEAQISE----------LQEDLESERAARNKAEKQRRDLGEELE 302
|
....*..
gi 295424207 764 NLTKELE 770
Cdd:pfam01576 303 ALKTELE 309
|
|
| HOOK |
pfam05622 |
HOOK protein coiled-coil region; This family consists of several HOOK1, 2 and 3 proteins from ... |
320-799 |
4.64e-03 |
|
HOOK protein coiled-coil region; This family consists of several HOOK1, 2 and 3 proteins from different eukaryotic organizms. The different members of the human gene family are HOOK1, HOOK2 and HOOK3. Different domains have been identified in the three human HOOK proteins, and it was demonstrated that the highly conserved NH2-domain mediates attachment to microtubules, whereas this central coiled-coil motif mediates homodimerization and the more divergent C-terminal domains are involved in binding to specific organelles (organelle-binding domains). It has been demonstrated that endogenous HOOK3 binds to Golgi membranes, whereas both HOOK1 and HOOK2 are localized to discrete but unidentified cellular structures. In mice the Hook1 gene is predominantly expressed in the testis. Hook1 function is necessary for the correct positioning of microtubular structures within the haploid germ cell. Disruption of Hook1 function in mice causes abnormal sperm head shape and fragile attachment of the flagellum to the sperm head. This entry includes the central coiled-coiled domain and the divergent C-terminal domain.
Pssm-ID: 461694 [Multi-domain] Cd Length: 528 Bit Score: 40.83 E-value: 4.64e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 320 QLRQKLAALSRQIDELEETNRSLRKAEEELQDIKDKINKGEYGNSGIMDEVDELRKRVldmegkdeelikmeEQCRDLNK 399
Cdd:pfam05622 11 ELAQRCHELDQQVSLLQEEKNSLQQENKKLQERLDQLESGDDSGTPGGKKYLLLQKQL--------------EQLQEENF 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 400 RLEKetvQSKDFKLEVDKLSVRITALEKLEDALDKSKQECYSLKCNLekekmttkqlsEELESLNARIKELEA-IESRLE 478
Cdd:pfam05622 77 RLET---ARDDYRIKCEELEKEVLELQHRNEELTSLAEEAQALKDEM-----------DILRESSDKVKKLEAtVETYKK 142
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 479 KTEitlkdDLTKLKTlTVMLVDERKTMSEKLK-QTEDKLQSTT---SQLQAEQNKVTTVTEKLIEETKRALKSKTD---A 551
Cdd:pfam05622 143 KLE-----DLGDLRR-QVKLLEERNAEYMQRTlQLEEELKKANalrGQLETYKRQVQELHGKLSEESKKADKLEFEykkL 216
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 552 EEKMYSVTKERDDLRNK----------LKAEEEKGHDLLSKVTILKNRLQSLEAIEKDFVKNKLnqdssKSTAALHQENN 621
Cdd:pfam05622 217 EEKLEALQKEKERLIIErdtlretneeLRCAQLQQAELSQADALLSPSSDPGDNLAAEIMPAEI-----REKLIRLQHEN 291
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 622 KIKELSQEvENLKLKLKDMKAIEDDLMKTEDEYETlERRYANERDKaqflsqELEHAKMELAKYKLAEKTESSHEQWLFR 701
Cdd:pfam05622 292 KMLRLGQE-GSYRERLTELQQLLEDANRRKNELET-QNRLANQRIL------ELQQQVEELQKALQEQGSKAEDSSLLKQ 363
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 702 RLQEEEAKSGHLSREVDALKEKIHEYMATEDLICHLQGDHslLQKKLNQQENRNRDLGreiENLTKELERYRHFSKSLRP 781
Cdd:pfam05622 364 KLEEHLEKLHEAQSELQKKKEQIEELEPKQDSNLAQKIDE--LQEALRKKDEDMKAME---ERYKKYVEKAKSVIKTLDP 438
|
490
....*....|....*...
gi 295424207 782 SLNERRISDPQVFSKEVQ 799
Cdd:pfam05622 439 KQNPASPPEIQALKNQLL 456
|
|
| COG2433 |
COG2433 |
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only]; |
326-490 |
4.72e-03 |
|
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
Pssm-ID: 441980 [Multi-domain] Cd Length: 644 Bit Score: 41.00 E-value: 4.72e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 326 AALSRQI-----DELEETNRSLRKAEEELQDIKDKINKGEygnsgimDEVDELRKRVLDMEG----KDEELIKMEEQCRD 396
Cdd:COG2433 380 EALEELIekelpEEEPEAEREKEHEERELTEEEEEIRRLE-------EQVERLEAEVEELEAeleeKDERIERLERELSE 452
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 397 LNKRLEKETVQSKdfklEVDKLSVRITALEKLedaldkskqecyslkcnLEKEKMTtkqlSEELESLNARIKELEAIESR 476
Cdd:COG2433 453 ARSEERREIRKDR----EISRLDREIERLERE-----------------LEEERER----IEELKRKLERLKELWKLEHS 507
|
170
....*....|....
gi 295424207 477 LEKTEITLKDDLTK 490
Cdd:COG2433 508 GELVPVKVVEKFTK 521
|
|
| AAA_13 |
pfam13166 |
AAA domain; This family of domains contain a P-loop motif that is characteriztic of the AAA ... |
297-472 |
5.40e-03 |
|
AAA domain; This family of domains contain a P-loop motif that is characteriztic of the AAA superfamily. Many of the proteins in this family are conjugative transfer proteins. This family includes the PrrC protein that is thought to be the active component of the anticodon nuclease.
Pssm-ID: 463796 [Multi-domain] Cd Length: 712 Bit Score: 40.81 E-value: 5.40e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 297 TTEFHQNQDKIMAKLTNEDSQNRQLRQKLAALSRQIDELEETNRSLRKAEEELQDIKDKINkgeygnsGIMDEVDELRK- 375
Cdd:pfam13166 278 DDEFTEFQNRLQKLIEKVESAISSLLAQLPAVSDLASLLSAFELDVEDIESEAEVLNSQLD-------GLRRALEAKRKd 350
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 376 --RVLDMEGKDEELIKMEEQCRDLNKRLEKETVQSKDFKLEVDKL--SVRITALEKLEDALDKSKQECYSLKCNLEKEKM 451
Cdd:pfam13166 351 pfKSIELDSVDAKIESINDLVASINELIAKHNEITDNFEEEKNKAkkKLRLHLVEEFKSEIDEYKDKYAGLEKAINSLEK 430
|
170 180
....*....|....*....|.
gi 295424207 452 TTKQLSEELESLNARIKELEA 472
Cdd:pfam13166 431 EIKNLEAEIKKLREEIKELEA 451
|
|
| RecN |
COG0497 |
DNA repair ATPase RecN [Replication, recombination and repair]; |
230-517 |
5.57e-03 |
|
DNA repair ATPase RecN [Replication, recombination and repair];
Pssm-ID: 440263 [Multi-domain] Cd Length: 555 Bit Score: 40.83 E-value: 5.57e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 230 LTKLKSFALMVVD-----EQQRLT---AQLAL---------QRQKIQALTTSAKETQGKLALAEARAQEEEQKATRLE-- 290
Cdd:COG0497 115 LSQLRELGELLVDihgqhEHQSLLdpdAQRELldafagleeLLEEYREAYRAWRALKKELEELRADEAERARELDLLRfq 194
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 291 -KELQTqttefhqnqdkimAKLT-NEDsqnrqlrqklaalsrqiDELEETNRSLRKAE---EELQDIKDKINKGEygnSG 365
Cdd:COG0497 195 lEELEA-------------AALQpGEE-----------------EELEEERRRLSNAEklrEALQEALEALSGGE---GG 241
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 366 IMDEVDELRKRVLDMEGKDEELikmeeqcRDLNKRLEKETVQSKDFKLEVDKLSVRITA----LEKLEDALDkskqECYS 441
Cdd:COG0497 242 ALDLLGQALRALERLAEYDPSL-------AELAERLESALIELEEAASELRRYLDSLEFdperLEEVEERLA----LLRR 310
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 295424207 442 LKcnlEKEKMTTKQLSEELESLNARIKELEAIESRLEKTEITLKDDLTKLKTLTVMLVDERKTMSEKL-KQTEDKLQ 517
Cdd:COG0497 311 LA---RKYGVTVEELLAYAEELRAELAELENSDERLEELEAELAEAEAELLEAAEKLSAARKKAAKKLeKAVTAELA 384
|
|
| PTZ00400 |
PTZ00400 |
DnaK-type molecular chaperone; Provisional |
539-621 |
5.95e-03 |
|
DnaK-type molecular chaperone; Provisional
Pssm-ID: 240403 [Multi-domain] Cd Length: 663 Bit Score: 40.58 E-value: 5.95e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 539 EETKRALKSKTDAEEKMYSVTKERDDLRNKLKAEEEKghDLLSKVTILKNRLQSLEAIEKDFVKNKLNQDSSKSTAALHQ 618
Cdd:PTZ00400 561 EKKKELVDAKNEAETLIYSVEKQLSDLKDKISDADKD--ELKQKITKLRSTLSSEDVDSIKDKTKQLQEASWKISQQAYK 638
|
...
gi 295424207 619 ENN 621
Cdd:PTZ00400 639 QGN 641
|
|
| COG4372 |
COG4372 |
Uncharacterized protein, contains DUF3084 domain [Function unknown]; |
223-490 |
6.13e-03 |
|
Uncharacterized protein, contains DUF3084 domain [Function unknown];
Pssm-ID: 443500 [Multi-domain] Cd Length: 370 Bit Score: 40.27 E-value: 6.13e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 223 IKTLKEELTKLKSFALMVVDEQQRLTAQLALQRQKIQALTTSAKETQGKLALAEARAQEEEQKATRLEKE---LQTQTTE 299
Cdd:COG4372 54 LEQAREELEQLEEELEQARSELEQLEEELEELNEQLQAAQAELAQAQEELESLQEEAEELQEELEELQKErqdLEQQRKQ 133
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 300 FHQNQDKIMAKLTNEDSQNRQLRQKLAALSRQIDELEETNRSLRKAE--EELQDIKDKINKGEYGNSGIMDEVDELRKRV 377
Cdd:COG4372 134 LEAQIAELQSEIAEREEELKELEEQLESLQEELAALEQELQALSEAEaeQALDELLKEANRNAEKEEELAEAEKLIESLP 213
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 378 LDMEGKDEELIKMEEQCRDLNKRLEKETVQSKDFKLEVDKLSVRITALEKLEDALDKSKQECYSLKCNLEKEKMTTKQLS 457
Cdd:COG4372 214 RELAEELLEAKDSLEAKLGLALSALLDALELEEDKEELLEEVILKEIEELELAILVEKDTEEEELEIAALELEALEEAAL 293
|
250 260 270
....*....|....*....|....*....|...
gi 295424207 458 EELESLNARIKELEAIESRLEKTEITLKDDLTK 490
Cdd:COG4372 294 ELKLLALLLNLAALSLIGALEDALLAALLELAK 326
|
|
| OmpH |
pfam03938 |
Outer membrane protein (OmpH-like); This family includes outer membrane proteins such as OmpH ... |
278-358 |
6.20e-03 |
|
Outer membrane protein (OmpH-like); This family includes outer membrane proteins such as OmpH among others. Skp (OmpH) has been characterized as a molecular chaperone that interacts with unfolded proteins as they emerge in the periplasm from the Sec translocation machinery.
Pssm-ID: 461098 [Multi-domain] Cd Length: 140 Bit Score: 38.33 E-value: 6.20e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 278 RAQEE-EQKATRLEKELQTQTTEFHQNQDKIMAKLTNEDSQNRQLRQKLAALSRQIDEL-EETNRSLRKAEEEL-QDIKD 354
Cdd:pfam03938 19 AAQAQlEKKFKKRQAELEAKQKELQKLYEELQKDGALLEEEREEKEQELQKKEQELQQLqQKAQQELQKKQQELlQPIQD 98
|
....
gi 295424207 355 KINK 358
Cdd:pfam03938 99 KINK 102
|
|
| COG0610 |
COG0610 |
Type I site-specific restriction-modification system, R (restriction) subunit and related ... |
229-438 |
6.52e-03 |
|
Type I site-specific restriction-modification system, R (restriction) subunit and related helicases ... [Defense mechanisms];
Pssm-ID: 440375 [Multi-domain] Cd Length: 936 Bit Score: 40.62 E-value: 6.52e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 229 ELTKLKSFALMVVDEQQRLTAQLALQRQKIQALTTSAKETQGKLALAEARAQEEE--QKATRLEKelqtqttefhqnqDK 306
Cdd:COG0610 735 ELSRLYNLLSPDDEFGDLELEKYRDDVSFYLALRAKLRKLGEKLDLKEYEEKIRQllDEAIDLER-------------KE 801
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 307 IMAKLTNEDSQNRQLRQKLAALsrqIDELEETNRSLRKAEEELQDIKDKINKGE--YGNSGIMDEVDELRKRVLDMEGKD 384
Cdd:COG0610 802 IKPRIKQNPVQYRKFSELLEEI---IEEYNNGALDADEVLEELEELAKEVKEEEerAEEEGLNEEELAFYDALAENLGDE 878
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 295424207 385 eeliKMEEQCRDLNKRLEKETvqSKDFKlevDKLSVRITALEKLEDALDKSKQE 438
Cdd:COG0610 879 ----KLKELAKELDDLLKKNV--TVDWR---KRESVRAKLRDAIKRLLRKYGYP 923
|
|
| PTZ00108 |
PTZ00108 |
DNA topoisomerase 2-like protein; Provisional |
320-696 |
7.38e-03 |
|
DNA topoisomerase 2-like protein; Provisional
Pssm-ID: 240271 [Multi-domain] Cd Length: 1388 Bit Score: 40.41 E-value: 7.38e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 320 QLRQKLAALSRQI--------DELEETNRSLRKAEEELQDIK----DKINKGEYGNSGIMDEVDELRKRVLDMEGKDEE- 386
Cdd:PTZ00108 1003 KLERELARLSNKVrfikhvinGELVITNAKKKDLVKELKKLGyvrfKDIIKKKSEKITAEEEEGAEEDDEADDEDDEEEl 1082
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 387 --------LIKM------EEQCRDLNKRLEkETVQSKDFKLEVDKLSVRITALEKLEDALDKSKQEcyslkcnLEKEKMT 452
Cdd:PTZ00108 1083 gaavsydyLLSMpiwsltKEKVEKLNAELE-KKEKELEKLKNTTPKDMWLEDLDKFEEALEEQEEV-------EEKEIAK 1154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 453 TKQLS--EELESLNARIKELEAIESRLEKTEITLKDDLTKLKTLTVMLVDERKTMSEKLKQTEDKLQSTTSQLQAEQNKV 530
Cdd:PTZ00108 1155 EQRLKskTKGKASKLRKPKLKKKEKKKKKSSADKSKKASVVGNSKRVDSDEKRKLDDKPDNKKSNSSGSDQEDDEEQKTK 1234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 531 ttvtEKLIEETKRALKSKTDAEEKMYSVTKERDDLRNKLKAEEEKGHdlLSKVTILKNRLQSLEAIEKDFvknklnqdSS 610
Cdd:PTZ00108 1235 ----PKKSSVKRLKSKKNNSSKSSEDNDEFSSDDLSKEGKPKNAPKR--VSAVQYSPPPPSKRPDGESNG--------GS 1300
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 611 KSTAALHQENNKIKELSQEVENLKLKLKDmKAIEDDLMKTEDEYETLERRYANERDKAQFLSQELEhakmELAKYKLAEK 690
Cdd:PTZ00108 1301 KPSSPTKKKVKKRLEGSLAALKKKKKSEK-KTARKKKSKTRVKQASASQSSRLLRRPRKKKSDSSS----EDDDDSEVDD 1375
|
....*.
gi 295424207 691 TESSHE 696
Cdd:PTZ00108 1376 SEDEDD 1381
|
|
| CwlO1 |
COG3883 |
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ... |
263-438 |
7.45e-03 |
|
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];
Pssm-ID: 443091 [Multi-domain] Cd Length: 379 Bit Score: 40.20 E-value: 7.45e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 263 TSAKETQGKLALAEARAQEEEQKATRLEKELQTQTTEFHQNQDKIMAKLTNEDSQNRQLRQKLAALSRQIDELEETNRSL 342
Cdd:COG3883 16 PQIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELGERARAL 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 343 RKAEEEL---------QDIKDKINKGEY------GNSGIMDEVDELRKRVldmEGKDEELIKMEEQCRDLNKRLE--KET 405
Cdd:COG3883 96 YRSGGSVsyldvllgsESFSDFLDRLSAlskiadADADLLEELKADKAEL---EAKKAELEAKLAELEALKAELEaaKAE 172
|
170 180 190
....*....|....*....|....*....|....*
gi 295424207 406 VQSKDFKLE--VDKLSVRITALEKLEDALDKSKQE 438
Cdd:COG3883 173 LEAQQAEQEalLAQLSAEEAAAEAQLAELEAELAA 207
|
|
| sbcc |
TIGR00618 |
exonuclease SbcC; All proteins in this family for which functions are known are part of an ... |
146-375 |
7.57e-03 |
|
exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 40.34 E-value: 7.57e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 146 EKHKESHRRILEQLLMVERSHRQTIMEMEEEKRK---HKEYMKKSDEFINLLEQECERLKKLIDQETASQEKKEQEKEKR 222
Cdd:TIGR00618 658 ERVREHALSIRVLPKELLASRQLALQKMQSEKEQltyWKEMLAQCQTLLRELETHIEEYDREFNEIENASSSLGSDLAAR 737
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 223 IKTLKEELTKLKSFALMV----VDEQQRLTAQLALQRQKIQALTTSAKETQGKLALAEARAQEEEQKATRLEKELQTQTT 298
Cdd:TIGR00618 738 EDALNQSLKELMHQARTVlkarTEAHFNNNEEVTAALQTGAELSHLAAEIQFFNRLREEDTHLLKTLEAEIGQEIPSDED 817
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 295424207 299 EFHQNQDKIMAKLTNEDSQNRQLRQKLAALSRQIDELEETNRSLRKAEEELQDIKDKINKGEYGNS-GIMDEVDELRK 375
Cdd:TIGR00618 818 ILNLQCETLVQEEEQFLSRLEEKSATLGEITHQLLKYEECSKQLAQLTQEQAKIIQLSDKLNGINQiKIQFDGDALIK 895
|
|
| COG1340 |
COG1340 |
Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown]; |
416-653 |
8.33e-03 |
|
Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown];
Pssm-ID: 440951 [Multi-domain] Cd Length: 297 Bit Score: 39.51 E-value: 8.33e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 416 DKLSVRITALEKLEDALDKSKQECYSLKCNLEKEKMTTKQLSEELESLNARIKEL-----EAIESRLEKTEI--TLKDDL 488
Cdd:COG1340 15 EKIEELREEIEELKEKRDELNEELKELAEKRDELNAQVKELREEAQELREKRDELnekvkELKEERDELNEKlnELREEL 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 489 TKLKTLTVMLVDER---KTMSEKLKQTEDKLQSTTSQLQAEQnkvttvteKLIEETKRaLKSKTDAEEKMYSVTKERDDL 565
Cdd:COG1340 95 DELRKELAELNKAGgsiDKLRKEIERLEWRQQTEVLSPEEEK--------ELVEKIKE-LEKELEKAKKALEKNEKLKEL 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 566 RNKLKAEEEKGHDLLSKVTILKNRLQSLEAI------EKDFVK---NKLNQDSSKSTAALHQENNKIKELSQEVENLKLK 636
Cdd:COG1340 166 RAELKELRKEAEEIHKKIKELAEEAQELHEEmielykEADELRkeaDELHKEIVEAQEKADELHEEIIELQKELRELRKE 245
|
250
....*....|....*..
gi 295424207 637 LKDMKAIEDDLMKTEDE 653
Cdd:COG1340 246 LKKLRKKQRALKREKEK 262
|
|
| PLN02939 |
PLN02939 |
transferase, transferring glycosyl groups |
230-463 |
9.44e-03 |
|
transferase, transferring glycosyl groups
Pssm-ID: 215507 [Multi-domain] Cd Length: 977 Bit Score: 40.27 E-value: 9.44e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 230 LTKLKSFALMVVDeqQRLTAQLALQrQKIQALTTSAKETQGKLALA---EARAQEEEQKATRLEKELQTQTTEFHQNQDK 306
Cdd:PLN02939 147 LNQARLQALEDLE--KILTEKEALQ-GKINILEMRLSETDARIKLAaqeKIHVEILEEQLEKLRNELLIRGATEGLCVHS 223
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 307 IMAKLTNEDSQNRQLRQKLAALSRQIDELEETNRSLRKAEEE-------LQDIKDKINKGEYGNSGI--------MDEVD 371
Cdd:PLN02939 224 LSKELDVLKEENMLLKDDIQFLKAELIEVAETEERVFKLEKErslldasLRELESKFIVAQEDVSKLsplqydcwWEKVE 303
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424207 372 ELRKRVLDMEGKDEELIKMEEQCRDLNKRLEK------ETVQSKDFKLEVDKLSVRITAlekLEDALDKSKQECYSlkcN 445
Cdd:PLN02939 304 NLQDLLDRATNQVEKAALVLDQNQDLRDKVDKleaslkEANVSKFSSYKVELLQQKLKL---LEERLQASDHEIHS---Y 377
|
250
....*....|....*...
gi 295424207 446 LEKEKMTTKQLSEELESL 463
Cdd:PLN02939 378 IQLYQESIKEFQDTLSKL 395
|
|
| |
