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Conserved domains on  [gi|85701706|ref|NP_001028363|]
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N-alpha-acetyltransferase 11 [Mus musculus]

Protein Classification

GNAT family N-acetyltransferase( domain architecture ID 11688059)

GNAT family N-acetyltransferase catalyzes the transfer of an acetyl group from acetyl-CoA to a substrate

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
RimI COG0456
Ribosomal protein S18 acetylase RimI and related acetyltransferases [Translation, ribosomal ...
 54-152 6.52e-19

Ribosomal protein S18 acetylase RimI and related acetyltransferases [Translation, ribosomal structure and biogenesis];


:

Pssm-ID: 440224 [Multi-domain]  Cd Length: 92  Bit Score: 78.16  E-value: 6.52e-19
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85701706  54 GYVLAKMEEDPDdvpHGHITSLAVKRSHRRLGLAQKLMDQASRAMIENfGAKYVSLHVRKSNRAALHLYSNtLNFQVSEV 133
Cdd:COG0456   1 GFALLGLVDGGD---EAEIEDLAVDPEYRGRGIGRALLEAALERARER-GARRLRLEVREDNEAAIALYEK-LGFEEVGE 75

                        90
                ....*....|....*....
gi 85701706 134 EPKYYADgeDAYAMKRDLS 152
Cdd:COG0456  76 RPNYYGD--DALVMEKELA 92
NAT_SF super family cl17182
N-Acyltransferase superfamily: Various enyzmes that characteristicly catalyze the transfer of ...
 1-94 8.37e-03

N-Acyltransferase superfamily: Various enyzmes that characteristicly catalyze the transfer of an acyl group to a substrate; NAT (N-Acyltransferase) is a large superfamily of enzymes that mostly catalyze the transfer of an acyl group to a substrate and are implicated in a variety of functions, from bacterial antibiotic resistance to circadian rhythms in mammals. Members include GCN5-related N-Acetyltransferases (GNAT) such as Aminoglycoside N-acetyltransferases, Histone N-acetyltransferase (HAT) enzymes, and Serotonin N-acetyltransferase which catalyze the transfer of an acetyl group to a substrate. The mechanism is an ordered Bi-Bi ternary complex kinetic mechanism for most GNATs: the reaction begins with Acetyl Coenzyme A (AcCoA) binding, followed by binding of substrate, then direct transfer of the acetyl group from AcCoA to the substrate, followed by product and then CoA release. Other family members include Arginine/ornithine N-succinyltransferase, Myristoyl-CoA: protein N-myristoyltransferase, and Acyl-homoserinelactone synthase which have a similar catalytic mechanism but differ in types of acyl groups transferred. Leucyl/ph enylalanyl-tRNA-protein transferase and FemXAB nonribosomal peptidyltransferases which catalyze similar peptidyltransferase reactions are also included.


The actual alignment was detected with superfamily member PRK07757:

Pssm-ID: 473072 [Multi-domain]  Cd Length: 152  Bit Score: 35.56  E-value: 8.37e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85701706    1 MNIRNARPDDLMNMQhcNLLclpenyqmKYYFYHGLSWPQ-LSYIAE--------DEDGKIVGYV-LAKMEEDpddvpHG 70
Cdd:PRK07757   2 MEIRKARLSDVKAIH--ALI--------NVYAKKGLMLPRsLDELYEnirdfyvaEEEGEIVGCCaLHILWED-----LA 66

                         90       100
                 ....*....|....*....|....
gi 85701706   71 HITSLAVKRSHRRLGLAQKLMDQA 94
Cdd:PRK07757  67 EIRSLAVSEDYRGQGIGRMLVEAC 90
 
Name Accession Description Interval E-value
RimI COG0456
Ribosomal protein S18 acetylase RimI and related acetyltransferases [Translation, ribosomal ...
 54-152 6.52e-19

Ribosomal protein S18 acetylase RimI and related acetyltransferases [Translation, ribosomal structure and biogenesis];


Pssm-ID: 440224 [Multi-domain]  Cd Length: 92  Bit Score: 78.16  E-value: 6.52e-19
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85701706  54 GYVLAKMEEDPDdvpHGHITSLAVKRSHRRLGLAQKLMDQASRAMIENfGAKYVSLHVRKSNRAALHLYSNtLNFQVSEV 133
Cdd:COG0456   1 GFALLGLVDGGD---EAEIEDLAVDPEYRGRGIGRALLEAALERARER-GARRLRLEVREDNEAAIALYEK-LGFEEVGE 75

                        90
                ....*....|....*....
gi 85701706 134 EPKYYADgeDAYAMKRDLS 152
Cdd:COG0456  76 RPNYYGD--DALVMEKELA 92
Acetyltransf_1 pfam00583
Acetyltransferase (GNAT) family; This family contains proteins with N-acetyltransferase ...
 28-122 2.75e-18

Acetyltransferase (GNAT) family; This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.


Pssm-ID: 395465 [Multi-domain]  Cd Length: 116  Bit Score: 77.17  E-value: 2.75e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85701706    28 MKYYFYHGLSWPQLSYIAEDEDGKIVGYVLAKMeeDPDDVPHGHITSLAVKRSHRRLGLAQKLMDQASRAMIEnFGAKYV 107
Cdd:pfam00583  20 PLDLLEDWDEDASEGFFVAEEDGELVGFASLSI--IDDEPPVGEIEGLAVAPEYRGKGIGTALLQALLEWARE-RGCERI 96

                          90
                  ....*....|....*
gi 85701706   108 SLHVRKSNRAALHLY 122
Cdd:pfam00583  97 FLEVAADNLAAIALY 111
NAT_SF cd04301
N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer ...
 42-110 5.71e-11

N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; NAT (N-Acyltransferase) is a large superfamily of enzymes that mostly catalyze the transfer of an acyl group to a substrate and are implicated in a variety of functions, ranging from bacterial antibiotic resistance to circadian rhythms in mammals. Members include GCN5-related N-Acetyltransferases (GNAT) such as Aminoglycoside N-acetyltransferases, Histone N-acetyltransferase (HAT) enzymes, and Serotonin N-acetyltransferase, which catalyze the transfer of an acetyl group to a substrate. The kinetic mechanism of most GNATs involves the ordered formation of a ternary complex: the reaction begins with Acetyl Coenzyme A (AcCoA) binding, followed by binding of substrate, then direct transfer of the acetyl group from AcCoA to the substrate, followed by product and subsequent CoA release. Other family members include Arginine/ornithine N-succinyltransferase, Myristoyl-CoA: protein N-myristoyltransferase, and Acyl-homoserinelactone synthase which have a similar catalytic mechanism but differ in types of acyl groups transferred. Leucyl/phenylalanyl-tRNA-protein transferase and FemXAB nonribosomal peptidyltransferases which catalyze similar peptidyltransferase reactions are also included.


Pssm-ID: 173926 [Multi-domain]  Cd Length: 65  Bit Score: 56.13  E-value: 5.71e-11
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 85701706  42 SYIAEDeDGKIVGYVLAKMEEDPDDvpHGHITSLAVKRSHRRLGLAQKLMDQASRAMIENfGAKYVSLH 110
Cdd:cd04301   1 FLVAED-DGEIVGFASLSPDGSGGD--TAYIGDLAVLPEYRGKGIGSALLEAAEEEARER-GAKRLRLE 65
PRK03624 PRK03624
putative acetyltransferase; Provisional
 39-133 8.40e-08

putative acetyltransferase; Provisional


Pssm-ID: 235142 [Multi-domain]  Cd Length: 140  Bit Score: 49.54  E-value: 8.40e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85701706   39 PQLSYIAEDeDGKIVGYVLAKMeedpdDVPHGHITSLAVKRSHRRLGLAQKLMDQASRAMIENfGAKYVSLHVRKSNRAA 118
Cdd:PRK03624  44 PSLFLVAEV-GGEVVGTVMGGY-----DGHRGWAYYLAVHPDFRGRGIGRALVARLEKKLIAR-GCPKINLQVREDNDAV 116

                         90
                 ....*....|....*
gi 85701706  119 LHLYSnTLNFQVSEV 133
Cdd:PRK03624 117 LGFYE-ALGYEEQDR 130
PRK07757 PRK07757
N-acetyltransferase;
1-94 8.37e-03

N-acetyltransferase;


Pssm-ID: 236088 [Multi-domain]  Cd Length: 152  Bit Score: 35.56  E-value: 8.37e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85701706    1 MNIRNARPDDLMNMQhcNLLclpenyqmKYYFYHGLSWPQ-LSYIAE--------DEDGKIVGYV-LAKMEEDpddvpHG 70
Cdd:PRK07757   2 MEIRKARLSDVKAIH--ALI--------NVYAKKGLMLPRsLDELYEnirdfyvaEEEGEIVGCCaLHILWED-----LA 66

                         90       100
                 ....*....|....*....|....
gi 85701706   71 HITSLAVKRSHRRLGLAQKLMDQA 94
Cdd:PRK07757  67 EIRSLAVSEDYRGQGIGRMLVEAC 90
 
Name Accession Description Interval E-value
RimI COG0456
Ribosomal protein S18 acetylase RimI and related acetyltransferases [Translation, ribosomal ...
 54-152 6.52e-19

Ribosomal protein S18 acetylase RimI and related acetyltransferases [Translation, ribosomal structure and biogenesis];


Pssm-ID: 440224 [Multi-domain]  Cd Length: 92  Bit Score: 78.16  E-value: 6.52e-19
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85701706  54 GYVLAKMEEDPDdvpHGHITSLAVKRSHRRLGLAQKLMDQASRAMIENfGAKYVSLHVRKSNRAALHLYSNtLNFQVSEV 133
Cdd:COG0456   1 GFALLGLVDGGD---EAEIEDLAVDPEYRGRGIGRALLEAALERARER-GARRLRLEVREDNEAAIALYEK-LGFEEVGE 75

                        90
                ....*....|....*....
gi 85701706 134 EPKYYADgeDAYAMKRDLS 152
Cdd:COG0456  76 RPNYYGD--DALVMEKELA 92
Acetyltransf_1 pfam00583
Acetyltransferase (GNAT) family; This family contains proteins with N-acetyltransferase ...
 28-122 2.75e-18

Acetyltransferase (GNAT) family; This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.


Pssm-ID: 395465 [Multi-domain]  Cd Length: 116  Bit Score: 77.17  E-value: 2.75e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85701706    28 MKYYFYHGLSWPQLSYIAEDEDGKIVGYVLAKMeeDPDDVPHGHITSLAVKRSHRRLGLAQKLMDQASRAMIEnFGAKYV 107
Cdd:pfam00583  20 PLDLLEDWDEDASEGFFVAEEDGELVGFASLSI--IDDEPPVGEIEGLAVAPEYRGKGIGTALLQALLEWARE-RGCERI 96

                          90
                  ....*....|....*
gi 85701706   108 SLHVRKSNRAALHLY 122
Cdd:pfam00583  97 FLEVAADNLAAIALY 111
yhbS COG3153
Predicted N-acetyltransferase YhbS [General function prediction only];
3-151 4.61e-14

Predicted N-acetyltransferase YhbS [General function prediction only];


Pssm-ID: 442387 [Multi-domain]  Cd Length: 142  Bit Score: 66.65  E-value: 4.61e-14
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85701706   3 IRNARPDDLMNMQHCNLLCLPENYQMKY-YFYHGLSWPQLSYIAEDeDGKIVGYVLAKMEEDPDDVPHGHITSLAVKRSH 81
Cdd:COG3153   1 IRPATPEDAEAIAALLRAAFGPGREAELvDRLREDPAAGLSLVAED-DGEIVGHVALSPVDIDGEGPALLLGPLAVDPEY 79

                        90       100       110       120       130       140       150
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85701706  82 RRLGLAQKLMDQASRAMIENfGAKYVSLHvrkSNRAALHLYSNtLNFQvsEVEPKYYADGEDAYAMKRDL 151
Cdd:COG3153  80 RGQGIGRALMRAALEAARER-GARAVVLL---GDPSLLPFYER-FGFR--PAGELGLTLGPDEVFLAKEL 142
ArgA COG1246
N-acetylglutamate synthase or related acetyltransferase, GNAT family [Amino acid transport and ...
 1-152 5.28e-12

N-acetylglutamate synthase or related acetyltransferase, GNAT family [Amino acid transport and metabolism]; N-acetylglutamate synthase or related acetyltransferase, GNAT family is part of the Pathway/BioSystem: Arginine biosynthesis


Pssm-ID: 440859 [Multi-domain]  Cd Length: 132  Bit Score: 60.78  E-value: 5.28e-12
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85701706   1 MNIRNARPDDLMNMQHcnlLCLPENYQMKYYFYhglswpqlsYIAEdEDGKIVGYV-LAKMEEDpddvpHGHITSLAVKR 79
Cdd:COG1246   1 MTIRPATPDDVPAILE---LIRPYALEEEIGEF---------WVAE-EDGEIVGCAaLHPLDED-----LAELRSLAVHP 62

                        90       100       110       120       130       140       150
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 85701706  80 SHRRLGLAQKLMDQA-SRAmiENFGAKYVSLHvrkSNRAALHLYSNtLNFQVSEVE--PKYYADGEDAYAMKRDLS 152
Cdd:COG1246  63 DYRGRGIGRRLLEALlAEA--RELGLKRLFLL---TTSAAIHFYEK-LGFEEIDKEdlPYAKVWQRDSVVMEKDLE 132
MnaT COG1247
L-amino acid N-acyltransferase MnaT [Amino acid transport and metabolism];
1-151 3.58e-11

L-amino acid N-acyltransferase MnaT [Amino acid transport and metabolism];


Pssm-ID: 440860 [Multi-domain]  Cd Length: 163  Bit Score: 59.24  E-value: 3.58e-11
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85701706   1 MNIRNARPDDLMNMQHCNLLCLPENY-----------QMKYYFYHGLSWPQLSYIAEdEDGKIVGYVLAKMEEDPDDVPH 69
Cdd:COG1247   2 MTIRPATPEDAPAIAAIYNEAIAEGTatfeteppseeEREAWFAAILAPGRPVLVAE-EDGEVVGFASLGPFRPRPAYRG 80

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85701706  70 GHITSLAVKRSHRRLGLAQKLMDQASRAMIENfGAKYVSLHVRKSNRAALHLYSNtLNFQVSEVEPK-YYADGE--DAYA 146
Cdd:COG1247  81 TAEESIYVDPDARGRGIGRALLEALIERARAR-GYRRLVAVVLADNEASIALYEK-LGFEEVGTLPEvGFKFGRwlDLVL 158


                ....*
gi 85701706 147 MKRDL 151
Cdd:COG1247 159 MQKRL 163
NAT_SF cd04301
N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer ...
 42-110 5.71e-11

N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; NAT (N-Acyltransferase) is a large superfamily of enzymes that mostly catalyze the transfer of an acyl group to a substrate and are implicated in a variety of functions, ranging from bacterial antibiotic resistance to circadian rhythms in mammals. Members include GCN5-related N-Acetyltransferases (GNAT) such as Aminoglycoside N-acetyltransferases, Histone N-acetyltransferase (HAT) enzymes, and Serotonin N-acetyltransferase, which catalyze the transfer of an acetyl group to a substrate. The kinetic mechanism of most GNATs involves the ordered formation of a ternary complex: the reaction begins with Acetyl Coenzyme A (AcCoA) binding, followed by binding of substrate, then direct transfer of the acetyl group from AcCoA to the substrate, followed by product and subsequent CoA release. Other family members include Arginine/ornithine N-succinyltransferase, Myristoyl-CoA: protein N-myristoyltransferase, and Acyl-homoserinelactone synthase which have a similar catalytic mechanism but differ in types of acyl groups transferred. Leucyl/phenylalanyl-tRNA-protein transferase and FemXAB nonribosomal peptidyltransferases which catalyze similar peptidyltransferase reactions are also included.


Pssm-ID: 173926 [Multi-domain]  Cd Length: 65  Bit Score: 56.13  E-value: 5.71e-11
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 85701706  42 SYIAEDeDGKIVGYVLAKMEEDPDDvpHGHITSLAVKRSHRRLGLAQKLMDQASRAMIENfGAKYVSLH 110
Cdd:cd04301   1 FLVAED-DGEIVGFASLSPDGSGGD--TAYIGDLAVLPEYRGKGIGSALLEAAEEEARER-GAKRLRLE 65
Acetyltransf_7 pfam13508
Acetyltransferase (GNAT) domain; This domain catalyzes N-acetyltransferase reactions.
 43-122 1.85e-09

Acetyltransferase (GNAT) domain; This domain catalyzes N-acetyltransferase reactions.


Pssm-ID: 463905 [Multi-domain]  Cd Length: 84  Bit Score: 52.84  E-value: 1.85e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85701706    43 YIAEDeDGKIVGYVLAKMEEDPDDVPHGHItslAVKRSHRRLGLAQKLMDQASRAMIENfGAKYVSLHVRksnRAALHLY 122
Cdd:pfam13508   6 FVAED-DGKIVGFAALLPLDDEGALAELRL---AVHPEYRGQGIGRALLEAAEAAAKEG-GIKLLELETT---NRAAAFY 77
COG3393 COG3393
Predicted acetyltransferase, GNAT family [General function prediction only];
56-122 2.24e-08

Predicted acetyltransferase, GNAT family [General function prediction only];


Pssm-ID: 442620 [Multi-domain]  Cd Length: 86  Bit Score: 49.91  E-value: 2.24e-08
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 85701706  56 VLAKMEEDPDDVPHGHITSLAVKRSHRRLGLAQKLMDQASRAMIENfGAKYVSLHVRKSNRAALHLY 122
Cdd:COG3393   2 LVAMAGVRAESPGVAEISGVYTHPEYRGRGLASALVAALAREALAR-GARTPFLYVDADNPAARRLY 67
PRK03624 PRK03624
putative acetyltransferase; Provisional
 39-133 8.40e-08

putative acetyltransferase; Provisional


Pssm-ID: 235142 [Multi-domain]  Cd Length: 140  Bit Score: 49.54  E-value: 8.40e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85701706   39 PQLSYIAEDeDGKIVGYVLAKMeedpdDVPHGHITSLAVKRSHRRLGLAQKLMDQASRAMIENfGAKYVSLHVRKSNRAA 118
Cdd:PRK03624  44 PSLFLVAEV-GGEVVGTVMGGY-----DGHRGWAYYLAVHPDFRGRGIGRALVARLEKKLIAR-GCPKINLQVREDNDAV 116

                         90
                 ....*....|....*
gi 85701706  119 LHLYSnTLNFQVSEV 133
Cdd:PRK03624 117 LGFYE-ALGYEEQDR 130
ElaA COG2153
Predicted N-acyltransferase, GNAT family [General function prediction only];
48-152 8.60e-08

Predicted N-acyltransferase, GNAT family [General function prediction only];


Pssm-ID: 441756 [Multi-domain]  Cd Length: 134  Bit Score: 49.41  E-value: 8.60e-08
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85701706  48 EDGKIVGY--VLakmeedPDDVPHGHITSLAVKRSHRRLGLAQKLMdQASRAMIENFGAKYVSLHVRKSnraALHLYSNt 125
Cdd:COG2153  41 DDGELVATarLL------PPGDGEAKIGRVAVLPEYRGQGLGRALM-EAAIEEARERGARRIVLSAQAH---AVGFYEK- 109

                        90       100
                ....*....|....*....|....*...
gi 85701706 126 LNFQ-VSEVepkYYADGEDAYAMKRDLS 152
Cdd:COG2153 110 LGFVpVGEE---FLEAGIPHIDMRKPLS 134
rimI PRK09491
ribosomal-protein-alanine N-acetyltransferase; Provisional
 75-147 8.47e-06

ribosomal-protein-alanine N-acetyltransferase; Provisional


Pssm-ID: 181904 [Multi-domain]  Cd Length: 146  Bit Score: 44.15  E-value: 8.47e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85701706   75 LAVKRSHRRLGLAQKLMdqasRAMIENFGAKYVS---LHVRKSNRAALHLYSNtLNF-QVSeVEPKYY--ADG-EDAYAM 147
Cdd:PRK09491  69 IAVDPDYQRQGLGRALL----EHLIDELEKRGVAtlwLEVRASNAAAIALYES-LGFnEVT-IRRNYYptADGrEDAIIM 142
RimL COG1670
Protein N-acetyltransferase, RimJ/RimL family [Translation, ribosomal structure and biogenesis, ...
 44-122 3.53e-05

Protein N-acetyltransferase, RimJ/RimL family [Translation, ribosomal structure and biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 441276 [Multi-domain]  Cd Length: 173  Bit Score: 42.68  E-value: 3.53e-05
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 85701706  44 IAEDEDGKIVGYVLAkMEEDPDDvPHGHItSLAVKRSHRRLGLAQKLMDQASRAMIENFGAKYVSLHVRKSNRAALHLY 122
Cdd:COG1670  65 IEDKEDGELIGVVGL-YDIDRAN-RSAEI-GYWLAPAYWGKGYATEALRALLDYAFEELGLHRVEAEVDPDNTASIRVL 140
Acetyltransf_10 pfam13673
Acetyltransferase (GNAT) domain; This family contains proteins with N-acetyltransferase ...
 47-151 3.90e-05

Acetyltransferase (GNAT) domain; This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.


Pssm-ID: 463953 [Multi-domain]  Cd Length: 128  Bit Score: 41.87  E-value: 3.90e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85701706    47 DEDGKIVGYVLAKMeedpddvpHGHITSLAVKRSHRRLGLAQKLMDQA-SRAMIENFGAKYVSLHvrkSNRAALHLYSnT 125
Cdd:pfam13673  37 FEGGQIVGVIALRD--------RGHISLLFVDPDYQGQGIGKALLEAVeDYAEKDGIKLSELTVN---ASPYAVPFYE-K 104

                          90       100
                  ....*....|....*....|....*.
gi 85701706   126 LNFQVSEVEpkYYADGEDAYAMKRDL 151
Cdd:pfam13673 105 LGFRATGPE--QEFNGIRFVPMEKEL 128
FR47 pfam08445
FR47-like protein; The members of this family are similar to the C-terminal region of the D. ...
 68-134 1.71e-04

FR47-like protein; The members of this family are similar to the C-terminal region of the D. melanogaster hypothetical protein FR47. This protein has been found to consist of two N-acyltransferase-like domains swapped with the C-terminal strands.


Pssm-ID: 117022 [Multi-domain]  Cd Length: 86  Bit Score: 39.24  E-value: 1.71e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 85701706    68 PHGHITSLAVKRSHRRLGLAQKLMDQASRAMIENfgAKYVSLHVRKSNRAALHLYSNtLNFQVSEVE 134
Cdd:pfam08445  20 PGGELGALQTLPEHRRRGLGSRLVAALARGIAER--GITPFAVVVAGNTPSRRLYEK-LGFRKIDET 83
PRK10975 PRK10975
dTDP-4-amino-4,6-dideoxy-D-galactose acyltransferase;
44-122 8.18e-04

dTDP-4-amino-4,6-dideoxy-D-galactose acyltransferase;


Pssm-ID: 182877  Cd Length: 194  Bit Score: 39.14  E-value: 8.18e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85701706   44 IAEDEDGKIVGYVLAKMEEDPDdvphGHITSLAVKRSHRRLGLAQKLMdQASRAMIENFGAKyvSLHV--RKSNRAALHL 121
Cdd:PRK10975 105 LLRDASGQIQGFVTLRELNDTD----ARIGLLAVFPGAQGRGIGARLM-QAALNWCQARGLT--RLRVatQMGNLAALRL 177


                 .
gi 85701706  122 Y 122
Cdd:PRK10975 178 Y 178
PRK09266 PRK09266
hypothetical protein; Provisional
 67-119 8.12e-03

hypothetical protein; Provisional


Pssm-ID: 236438  Cd Length: 266  Bit Score: 36.50  E-value: 8.12e-03
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 85701706   67 VPHGHITSLAVkRSHRRLGLAQKL--MDQASRAMienFGAKYVSLHVRKSNRAAL 119
Cdd:PRK09266  23 ANYGHFTSMQV-RDGRVRGLDLHLqrLRRASREL---FGAALDDDRVRAQLRAAL 73
PRK07757 PRK07757
N-acetyltransferase;
1-94 8.37e-03

N-acetyltransferase;


Pssm-ID: 236088 [Multi-domain]  Cd Length: 152  Bit Score: 35.56  E-value: 8.37e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85701706    1 MNIRNARPDDLMNMQhcNLLclpenyqmKYYFYHGLSWPQ-LSYIAE--------DEDGKIVGYV-LAKMEEDpddvpHG 70
Cdd:PRK07757   2 MEIRKARLSDVKAIH--ALI--------NVYAKKGLMLPRsLDELYEnirdfyvaEEEGEIVGCCaLHILWED-----LA 66

                         90       100
                 ....*....|....*....|....
gi 85701706   71 HITSLAVKRSHRRLGLAQKLMDQA 94
Cdd:PRK07757  67 EIRSLAVSEDYRGQGIGRMLVEAC 90
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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