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Conserved domains on  [gi|2117900732|ref|NP_001025749|]
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kelch domain-containing protein 4 [Gallus gallus]

Protein Classification

Kelch repeat-containing protein( domain architecture ID 11459646)

Kelch repeat-containing protein, member of a superfamily of proteins with diverse functions

CATH:  2.120.10.80
Gene Ontology:  GO:0005515
PubMed:  10603472|31442578|24959344
SCOP:  3000448

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
NanM COG3055
N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];
59-369 2.18e-29

N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];


:

Pssm-ID: 442289 [Multi-domain]  Cd Length: 277  Bit Score: 117.56  E-value: 2.18e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2117900732  59 PPPSPRLNGSLSAHPEKdelILFGGEYFNGQktyLYNDLYVYNIRKNSWTKVEiPNPPPRRcaHQAAVVpTAGGQLWVFG 138
Cdd:COG3055     8 DLPTPRSEAAAALLDGK---VYVAGGLSGGS---ASNSFEVYDPATNTWSELA-PLPGPPR--HHAAAV-AQDGKLYVFG 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2117900732 139 GEFASPSGEQFYhyKDLWVLHLATKTWEQIKASggPSGRSGHRMVACKRQLIIFGGFHESArdyiYYNDVYAFNLDSFTW 218
Cdd:COG3055    78 GFTGANPSSTPL--NDVYVYDPATNTWTKLAPM--PTPRGGATALLLDGKIYVVGGWDDGG----NVAWVEVYDPATGTW 149

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2117900732 219 SKLAPSgigPAPRSGCQMATTPEGSIVIYGGYSkqrvkkdvdkGTLHTDmfllktegsgkeedkwVWSRLNPSgvkPTPR 298
Cdd:COG3055   150 TQLAPL---PTPRDHLAAAVLPDGKILVIGGRN----------GSGFSN----------------TWTTLAPL---PTAR 197

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2117900732 299 SGFSVAIgPNNRSLLFGGvhdeeeeesiEGDFFNDIYFYDTGKNRWFP-GQLKVPksekrkRRRGRQAETDG 369
Cdd:COG3055   198 AGHAAAV-LGGKILVFGG----------ESGFSDEVEAYDPATNTWTAlGELPTP------RHGHAAVLTDG 252
 
Name Accession Description Interval E-value
NanM COG3055
N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];
59-369 2.18e-29

N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442289 [Multi-domain]  Cd Length: 277  Bit Score: 117.56  E-value: 2.18e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2117900732  59 PPPSPRLNGSLSAHPEKdelILFGGEYFNGQktyLYNDLYVYNIRKNSWTKVEiPNPPPRRcaHQAAVVpTAGGQLWVFG 138
Cdd:COG3055     8 DLPTPRSEAAAALLDGK---VYVAGGLSGGS---ASNSFEVYDPATNTWSELA-PLPGPPR--HHAAAV-AQDGKLYVFG 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2117900732 139 GEFASPSGEQFYhyKDLWVLHLATKTWEQIKASggPSGRSGHRMVACKRQLIIFGGFHESArdyiYYNDVYAFNLDSFTW 218
Cdd:COG3055    78 GFTGANPSSTPL--NDVYVYDPATNTWTKLAPM--PTPRGGATALLLDGKIYVVGGWDDGG----NVAWVEVYDPATGTW 149

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2117900732 219 SKLAPSgigPAPRSGCQMATTPEGSIVIYGGYSkqrvkkdvdkGTLHTDmfllktegsgkeedkwVWSRLNPSgvkPTPR 298
Cdd:COG3055   150 TQLAPL---PTPRDHLAAAVLPDGKILVIGGRN----------GSGFSN----------------TWTTLAPL---PTAR 197

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2117900732 299 SGFSVAIgPNNRSLLFGGvhdeeeeesiEGDFFNDIYFYDTGKNRWFP-GQLKVPksekrkRRRGRQAETDG 369
Cdd:COG3055   198 AGHAAAV-LGGKILVFGG----------ESGFSDEVEAYDPATNTWTAlGELPTP------RHGHAAVLTDG 252
PLN02193 PLN02193
nitrile-specifier protein
 77-316 1.21e-16

nitrile-specifier protein


Pssm-ID: 177844 [Multi-domain]  Cd Length: 470  Bit Score: 82.70  E-value: 1.21e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2117900732  77 ELILFGGEY--FNGQKTYLYNDLYVYNIRKNS------WTKVEIPNPPP-RRCAHQAAVVptaGGQLWVFGGEFaSPSGE 147
Cdd:PLN02193  115 KFVLQGGKIvgFHGRSTDVLHSLGAYISLPSTpkllgkWIKVEQKGEGPgLRCSHGIAQV---GNKIYSFGGEF-TPNQP 190

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2117900732 148 QFYHykdLWVLHLATKTWEQIKASGGPSGRS--GHRMVACKRQLIIFGGFHESARdyiyYNDVYAFNLDSFTWSKLAPSG 225
Cdd:PLN02193  191 IDKH---LYVFDLETRTWSISPATGDVPHLSclGVRMVSIGSTLYVFGGRDASRQ----YNGFYSFDTTTNEWKLLTPVE 263

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2117900732 226 IGPAPRSGCQMATTPEgSIVIYGGYS-KQRVK-----KDVDKGTLHT----DMFLLKTeGSGKE---------------- 279
Cdd:PLN02193  264 EGPTPRSFHSMAADEE-NVYVFGGVSaTARLKtldsyNIVDKKWFHCstpgDSFSIRG-GAGLEvvqgkvwvvygfngce 341

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*...
gi 2117900732 280 ----------EDKwvWSRLNPSGVKPTPRSGF-SVAIGpnNRSLLFGG 316
Cdd:PLN02193  342 vddvhyydpvQDK--WTQVETFGVRPSERSVFaSAAVG--KHIVIFGG 385
Kelch_4 pfam13418
Galactose oxidase, central domain;
63-117 3.69e-10

Galactose oxidase, central domain;


Pssm-ID: 433191 [Multi-domain]  Cd Length: 49  Bit Score: 55.31  E-value: 3.69e-10
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 2117900732  63 PRLNGSLSAHPeKDELILFGGEYFNGQktyLYNDLYVYNIRKNSWTKveIPNPPP 117
Cdd:pfam13418   1 PRAYHTSTSIP-DDTIYLFGGEGEDGT---LLSDLWVFDLSTNEWTR--LGSLPS 49
 
Name Accession Description Interval E-value
NanM COG3055
N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];
59-369 2.18e-29

N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442289 [Multi-domain]  Cd Length: 277  Bit Score: 117.56  E-value: 2.18e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2117900732  59 PPPSPRLNGSLSAHPEKdelILFGGEYFNGQktyLYNDLYVYNIRKNSWTKVEiPNPPPRRcaHQAAVVpTAGGQLWVFG 138
Cdd:COG3055     8 DLPTPRSEAAAALLDGK---VYVAGGLSGGS---ASNSFEVYDPATNTWSELA-PLPGPPR--HHAAAV-AQDGKLYVFG 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2117900732 139 GEFASPSGEQFYhyKDLWVLHLATKTWEQIKASggPSGRSGHRMVACKRQLIIFGGFHESArdyiYYNDVYAFNLDSFTW 218
Cdd:COG3055    78 GFTGANPSSTPL--NDVYVYDPATNTWTKLAPM--PTPRGGATALLLDGKIYVVGGWDDGG----NVAWVEVYDPATGTW 149

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2117900732 219 SKLAPSgigPAPRSGCQMATTPEGSIVIYGGYSkqrvkkdvdkGTLHTDmfllktegsgkeedkwVWSRLNPSgvkPTPR 298
Cdd:COG3055   150 TQLAPL---PTPRDHLAAAVLPDGKILVIGGRN----------GSGFSN----------------TWTTLAPL---PTAR 197

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2117900732 299 SGFSVAIgPNNRSLLFGGvhdeeeeesiEGDFFNDIYFYDTGKNRWFP-GQLKVPksekrkRRRGRQAETDG 369
Cdd:COG3055   198 AGHAAAV-LGGKILVFGG----------ESGFSDEVEAYDPATNTWTAlGELPTP------RHGHAAVLTDG 252
NanM COG3055
N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];
59-253 1.47e-17

N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442289 [Multi-domain]  Cd Length: 277  Bit Score: 83.28  E-value: 1.47e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2117900732  59 PPPSPRLNGSLSAHPEkDELILFGGEYFNGQKTYLYNDLYVYNIRKNSWTKveIPNPPPRRCAHQAAVVptaGGQLWVFG 138
Cdd:COG3055    55 PLPGPPRHHAAAVAQD-GKLYVFGGFTGANPSSTPLNDVYVYDPATNTWTK--LAPMPTPRGGATALLL---DGKIYVVG 128

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2117900732 139 GEFASPsgeqfyHYKDLWVLHLATKTWEQIK--------------------ASGG----------------PSGRSGHRM 182
Cdd:COG3055   129 GWDDGG------NVAWVEVYDPATGTWTQLAplptprdhlaaavlpdgkilVIGGrngsgfsntwttlaplPTARAGHAA 202

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2117900732 183 VACKRQLIIFGGFHEsardyiYYNDVYAFNLDSFTWSKLAPSgigPAPRSGCQMATTpEGSIVIYGGYSKQ 253
Cdd:COG3055   203 AVLGGKILVFGGESG------FSDEVEAYDPATNTWTALGEL---PTPRHGHAAVLT-DGKVYVIGGETKP 263
PLN02193 PLN02193
nitrile-specifier protein
 77-316 1.21e-16

nitrile-specifier protein


Pssm-ID: 177844 [Multi-domain]  Cd Length: 470  Bit Score: 82.70  E-value: 1.21e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2117900732  77 ELILFGGEY--FNGQKTYLYNDLYVYNIRKNS------WTKVEIPNPPP-RRCAHQAAVVptaGGQLWVFGGEFaSPSGE 147
Cdd:PLN02193  115 KFVLQGGKIvgFHGRSTDVLHSLGAYISLPSTpkllgkWIKVEQKGEGPgLRCSHGIAQV---GNKIYSFGGEF-TPNQP 190

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2117900732 148 QFYHykdLWVLHLATKTWEQIKASGGPSGRS--GHRMVACKRQLIIFGGFHESARdyiyYNDVYAFNLDSFTWSKLAPSG 225
Cdd:PLN02193  191 IDKH---LYVFDLETRTWSISPATGDVPHLSclGVRMVSIGSTLYVFGGRDASRQ----YNGFYSFDTTTNEWKLLTPVE 263

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2117900732 226 IGPAPRSGCQMATTPEgSIVIYGGYS-KQRVK-----KDVDKGTLHT----DMFLLKTeGSGKE---------------- 279
Cdd:PLN02193  264 EGPTPRSFHSMAADEE-NVYVFGGVSaTARLKtldsyNIVDKKWFHCstpgDSFSIRG-GAGLEvvqgkvwvvygfngce 341

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*...
gi 2117900732 280 ----------EDKwvWSRLNPSGVKPTPRSGF-SVAIGpnNRSLLFGG 316
Cdd:PLN02193  342 vddvhyydpvQDK--WTQVETFGVRPSERSVFaSAAVG--KHIVIFGG 385
PLN02153 PLN02153
epithiospecifier protein
 61-316 2.76e-12

epithiospecifier protein


Pssm-ID: 177814 [Multi-domain]  Cd Length: 341  Bit Score: 68.09  E-value: 2.76e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2117900732  61 PSPRLNGSLSAhpEKDELILFGGEYFNGQktYLYNDLYVYNIRKNSWTKVEIPNPPPRRCAHQAAVVpTAGGQLWVFGGE 140
Cdd:PLN02153   20 PGPRCSHGIAV--VGDKLYSFGGELKPNE--HIDKDLYVFDFNTHTWSIAPANGDVPRISCLGVRMV-AVGTKLYIFGGR 94

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2117900732 141 FASPSGEQFYHYKDLwvlhlaTKTWE---QIKASGGPSGRSGHRMVACKRQLIIFGGFHESA--RDYIYYNDVYAFNLDS 215
Cdd:PLN02153   95 DEKREFSDFYSYDTV------KNEWTfltKLDEEGGPEARTFHSMASDENHVYVFGGVSKGGlmKTPERFRTIEAYNIAD 168

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2117900732 216 FTWSKLAPSGIGPAPRSGCQMATTpEGSIVIYGGYSKQRVKKdvDKGTLHTDMFLLKTEGSGKeedkwvWSRLNPSGVKP 295
Cdd:PLN02153  169 GKWVQLPDPGENFEKRGGAGFAVV-QGKIWVVYGFATSILPG--GKSDYESNAVQFFDPASGK------WTEVETTGAKP 239

                         250       260
                  ....*....|....*....|.
gi 2117900732 296 TPRSGFSVAIgPNNRSLLFGG 316
Cdd:PLN02153  240 SARSVFAHAV-VGKYIIIFGG 259
Kelch_4 pfam13418
Galactose oxidase, central domain;
63-117 3.69e-10

Galactose oxidase, central domain;


Pssm-ID: 433191 [Multi-domain]  Cd Length: 49  Bit Score: 55.31  E-value: 3.69e-10
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 2117900732  63 PRLNGSLSAHPeKDELILFGGEYFNGQktyLYNDLYVYNIRKNSWTKveIPNPPP 117
Cdd:pfam13418   1 PRAYHTSTSIP-DDTIYLFGGEGEDGT---LLSDLWVFDLSTNEWTR--LGSLPS 49
Kelch_3 pfam13415
Galactose oxidase, central domain;
75-127 1.75e-07

Galactose oxidase, central domain;


Pssm-ID: 433188 [Multi-domain]  Cd Length: 49  Bit Score: 47.67  E-value: 1.75e-07
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|...
gi 2117900732  75 KDELILFGGEYFNGQKtyLYNDLYVYNIRKNSWTKVEIPnPPPRRCaHQAAVV 127
Cdd:pfam13415   1 GDKLYIFGGLGFDGQT--RLNDLYVYDLDTNTWTQIGDL-PPPRSG-HSATYI 49
PLN02153 PLN02153
epithiospecifier protein
 61-231 2.27e-07

epithiospecifier protein


Pssm-ID: 177814 [Multi-domain]  Cd Length: 341  Bit Score: 53.07  E-value: 2.27e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2117900732  61 PSPRLNGSLSAhpEKDELILFGGEYFNGQKTY--LYNDLYVYNIRKNSWtkVEIPNPPPRRCAHQAAVVPTAGGQLWVFG 138
Cdd:PLN02153  125 PEARTFHSMAS--DENHVYVFGGVSKGGLMKTpeRFRTIEAYNIADGKW--VQLPDPGENFEKRGGAGFAVVQGKIWVVY 200

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2117900732 139 GeFAS---PSGEQFYHYKDLWVLHLATKTWEQIKASGG-PSGRSGHRMVACKRQLIIFGGfhESARDY-------IYYND 207
Cdd:PLN02153  201 G-FATsilPGGKSDYESNAVQFFDPASGKWTEVETTGAkPSARSVFAHAVVGKYIIIFGG--EVWPDLkghlgpgTLSNE 277

                         170       180
                  ....*....|....*....|....
gi 2117900732 208 VYAFNLDSFTWSKLAPSGIGPAPR 231
Cdd:PLN02153  278 GYALDTETLVWEKLGECGEPAMPR 301
Kelch_5 pfam13854
Kelch motif; The kelch motif was initially discovered in Kelch. In this protein there are six ...
 174-216 4.60e-06

Kelch motif; The kelch motif was initially discovered in Kelch. In this protein there are six copies of the motif. It has been shown that Swiss:Q04652 is related to Galactose Oxidase for which a structure has been solved. The kelch motif forms a beta sheet. Several of these sheets associate to form a beta propeller structure as found in pfam00064, pfam00400 and pfam00415.


Pssm-ID: 433528 [Multi-domain]  Cd Length: 41  Bit Score: 43.71  E-value: 4.60e-06
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|...
gi 2117900732 174 PSGRSGHRMVACKRQLIIFGGFheSARDYIYYNDVYAFNLDSF 216
Cdd:pfam13854   1 PVPRYGHCAVTVGDYIYLYGGY--TGGEGQPSDDVYVLSLPTF 41
Kelch_3 pfam13415
Galactose oxidase, central domain;
131-184 1.51e-05

Galactose oxidase, central domain;


Pssm-ID: 433188 [Multi-domain]  Cd Length: 49  Bit Score: 42.28  E-value: 1.51e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....
gi 2117900732 131 GGQLWVFGGEFasPSGEQFYHykDLWVLHLATKTWEQIKASggPSGRSGHRMVA 184
Cdd:pfam13415   1 GDKLYIFGGLG--FDGQTRLN--DLYVYDLDTNTWTQIGDL--PPPRSGHSATY 48
PRK14131 PRK14131
N-acetylneuraminate epimerase;
163-253 2.44e-05

N-acetylneuraminate epimerase;


Pssm-ID: 237617 [Multi-domain]  Cd Length: 376  Bit Score: 46.93  E-value: 2.44e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2117900732 163 KTWEQIKA-SGGPsgRSGHRMVACKRQLIIFGGFHESARD--YIYYNDVYAFNLDSFTWSKL---APSGIgpaprSGCQM 236
Cdd:PRK14131   62 KGWTKIAAfPGGP--REQAVAAFIDGKLYVFGGIGKTNSEgsPQVFDDVYKYDPKTNSWQKLdtrSPVGL-----AGHVA 134

                          90
                  ....*....|....*..
gi 2117900732 237 ATTPEGSIVIYGGYSKQ 253
Cdd:PRK14131  135 VSLHNGKAYITGGVNKN 151
Kelch_4 pfam13418
Galactose oxidase, central domain;
176-224 2.79e-05

Galactose oxidase, central domain;


Pssm-ID: 433191 [Multi-domain]  Cd Length: 49  Bit Score: 41.44  E-value: 2.79e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|
gi 2117900732 176 GRSGHRMVAC-KRQLIIFGGFHEsarDYIYYNDVYAFNLDSFTWSKLAPS 224
Cdd:pfam13418   1 PRAYHTSTSIpDDTIYLFGGEGE---DGTLLSDLWVFDLSTNEWTRLGSL 47
PRK14131 PRK14131
N-acetylneuraminate epimerase;
76-248 3.18e-05

N-acetylneuraminate epimerase;


Pssm-ID: 237617 [Multi-domain]  Cd Length: 376  Bit Score: 46.55  E-value: 3.18e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2117900732  76 DELILFGG--EYFNGQKTYLYNDLYVYNIRKNSWTKVeiPNPPPRRCAHQAAVVPtAGGQLWVFGGefaspsgeqfyhyk 153
Cdd:PRK14131   85 GKLYVFGGigKTNSEGSPQVFDDVYKYDPKTNSWQKL--DTRSPVGLAGHVAVSL-HNGKAYITGG-------------- 147

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2117900732 154 dlWVLHLATKTWEQIKASGGPSGrsghrmvacKRQLIIFGGFHESARDYIYYNDVYAFNLDSFTWSKLapsGIGP-APRS 232
Cdd:PRK14131  148 --VNKNIFDGYFEDLAAAGKDKT---------PKDKINDAYFDKKPEDYFFNKEVLSYDPSTNQWKNA---GESPfLGTA 213

                         170
                  ....*....|....*.
gi 2117900732 233 GCQMATTPEGSIVIYG 248
Cdd:PRK14131  214 GSAVVIKGNKLWLING 229
Kelch_3 pfam13415
Galactose oxidase, central domain;
186-237 5.80e-05

Galactose oxidase, central domain;


Pssm-ID: 433188 [Multi-domain]  Cd Length: 49  Bit Score: 40.74  E-value: 5.80e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|..
gi 2117900732 186 KRQLIIFGGFHESARDYiyYNDVYAFNLDSFTWSKLAPSgigPAPRSGCQMA 237
Cdd:pfam13415   1 GDKLYIFGGLGFDGQTR--LNDLYVYDLDTNTWTQIGDL---PPPRSGHSAT 47
Kelch_1 pfam01344
Kelch motif; The kelch motif was initially discovered in Kelch. In this protein there are six ...
 177-223 1.95e-04

Kelch motif; The kelch motif was initially discovered in Kelch. In this protein there are six copies of the motif. It has been shown that Swiss:Q04652 is related to Galactose Oxidase for which a structure has been solved. The kelch motif forms a beta sheet. Several of these sheets associate to form a beta propeller structure as found in pfam00064, pfam00400 and pfam00415.


Pssm-ID: 396078 [Multi-domain]  Cd Length: 46  Bit Score: 39.13  E-value: 1.95e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*..
gi 2117900732 177 RSGHRMVACKRQLIIFGGFHESARDyiyyNDVYAFNLDSFTWSKLAP 223
Cdd:pfam01344   2 RSGAGVVVVGGKIYVIGGFDGNQSL----NSVEVYDPETNTWSKLPS 44
Kelch_4 pfam13418
Galactose oxidase, central domain;
117-171 5.08e-04

Galactose oxidase, central domain;


Pssm-ID: 433191 [Multi-domain]  Cd Length: 49  Bit Score: 37.98  E-value: 5.08e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 2117900732 117 PRRCAhqaAVVPTAGGQLWVFGGEFASPSGeqfyhYKDLWVLHLATKTWEQIKAS 171
Cdd:pfam13418   1 PRAYH---TSTSIPDDTIYLFGGEGEDGTL-----LSDLWVFDLSTNEWTRLGSL 47
Kelch_6 pfam13964
Kelch motif;
119-168 6.29e-04

Kelch motif;


Pssm-ID: 404790 [Multi-domain]  Cd Length: 50  Bit Score: 37.70  E-value: 6.29e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|
gi 2117900732 119 RCAHQAAVVptaGGQLWVFGGefaspSGEQFYHYKDLWVLHLATKTWEQI 168
Cdd:pfam13964   2 RTFHSVVSV---GGYIYVFGG-----YTNASPALNKLEVYNPLTKSWEEL 43
Kelch_4 pfam13418
Galactose oxidase, central domain;
297-344 5.96e-03

Galactose oxidase, central domain;


Pssm-ID: 433191 [Multi-domain]  Cd Length: 49  Bit Score: 34.90  E-value: 5.96e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*...
gi 2117900732 297 PRSGFSVAIGPNNRSLLFGGvhdeeeeESIEGDFFNDIYFYDTGKNRW 344
Cdd:pfam13418   1 PRAYHTSTSIPDDTIYLFGG-------EGEDGTLLSDLWVFDLSTNEW 41
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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