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Conserved domains on  [gi|57863295|ref|NP_001009880|]
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uncharacterized protein KIAA0930 isoform b [Homo sapiens]

Protein Classification

DUF2045 domain-containing protein( domain architecture ID 10560859)

DUF2045 domain-containing protein similar to Homo sapiens protein KIAA0930

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
DUF2045 pfam09741
Uncharacterized conserved protein (DUF2045); This entry is the conserved 250 residues of ...
30-257 1.57e-135

Uncharacterized conserved protein (DUF2045); This entry is the conserved 250 residues of proteins of approximately 450 amino acids. It contains several highly conserved motifs including a CVxLxxxD motif.The function is unknown.


:

Pssm-ID: 462872  Cd Length: 223  Bit Score: 386.69  E-value: 1.57e-135
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 57863295    30 VFWTWMFSTYFMEKWAPR---QDDMLFYVRRKLAYSGSESGadgrkaaePEVEVEVYRRDSKKLPGLGDPDIDWEESVCL 106
Cdd:pfam09741   1 VFWTELFDKYFIRARCSRhrhQDDLLFFVRKNLLLSGSKGK--------PQGPVFVYRRDSKWAPKLGDPEVDWEETVYL 72
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 57863295   107 NLILQKLDYMVTCAVCTRADGGDIHIHKKKSQQVFASPSKHPMDSKGEESKISYPNIFFMIDSFEEVFSDMTVGEGEMVC 186
Cdd:pfam09741  73 NLIAQQTDYTLTCAVCTRTSPQELQPLYKVSQRVYASPSRRRMDLKGEETEITYPNICFAVDDFEETFSDVVVRDGECVC 152
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 57863295   187 VELVASDKTNTFQGVIFQGSIRYEALKKVYDNRVSVAARMAQKMSFGFYKYSNMEFVRMKGPQGKGHAEMA 257
Cdd:pfam09741 153 VELVAHDRAAFFKGVLFSGSVRYEMLRKAYDARASSAKSWAQKLLSSGGLQGRVEFVRMKGPGGKGEAEMA 223
 
Name Accession Description Interval E-value
DUF2045 pfam09741
Uncharacterized conserved protein (DUF2045); This entry is the conserved 250 residues of ...
30-257 1.57e-135

Uncharacterized conserved protein (DUF2045); This entry is the conserved 250 residues of proteins of approximately 450 amino acids. It contains several highly conserved motifs including a CVxLxxxD motif.The function is unknown.


Pssm-ID: 462872  Cd Length: 223  Bit Score: 386.69  E-value: 1.57e-135
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 57863295    30 VFWTWMFSTYFMEKWAPR---QDDMLFYVRRKLAYSGSESGadgrkaaePEVEVEVYRRDSKKLPGLGDPDIDWEESVCL 106
Cdd:pfam09741   1 VFWTELFDKYFIRARCSRhrhQDDLLFFVRKNLLLSGSKGK--------PQGPVFVYRRDSKWAPKLGDPEVDWEETVYL 72
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 57863295   107 NLILQKLDYMVTCAVCTRADGGDIHIHKKKSQQVFASPSKHPMDSKGEESKISYPNIFFMIDSFEEVFSDMTVGEGEMVC 186
Cdd:pfam09741  73 NLIAQQTDYTLTCAVCTRTSPQELQPLYKVSQRVYASPSRRRMDLKGEETEITYPNICFAVDDFEETFSDVVVRDGECVC 152
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 57863295   187 VELVASDKTNTFQGVIFQGSIRYEALKKVYDNRVSVAARMAQKMSFGFYKYSNMEFVRMKGPQGKGHAEMA 257
Cdd:pfam09741 153 VELVAHDRAAFFKGVLFSGSVRYEMLRKAYDARASSAKSWAQKLLSSGGLQGRVEFVRMKGPGGKGEAEMA 223
 
Name Accession Description Interval E-value
DUF2045 pfam09741
Uncharacterized conserved protein (DUF2045); This entry is the conserved 250 residues of ...
30-257 1.57e-135

Uncharacterized conserved protein (DUF2045); This entry is the conserved 250 residues of proteins of approximately 450 amino acids. It contains several highly conserved motifs including a CVxLxxxD motif.The function is unknown.


Pssm-ID: 462872  Cd Length: 223  Bit Score: 386.69  E-value: 1.57e-135
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 57863295    30 VFWTWMFSTYFMEKWAPR---QDDMLFYVRRKLAYSGSESGadgrkaaePEVEVEVYRRDSKKLPGLGDPDIDWEESVCL 106
Cdd:pfam09741   1 VFWTELFDKYFIRARCSRhrhQDDLLFFVRKNLLLSGSKGK--------PQGPVFVYRRDSKWAPKLGDPEVDWEETVYL 72
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 57863295   107 NLILQKLDYMVTCAVCTRADGGDIHIHKKKSQQVFASPSKHPMDSKGEESKISYPNIFFMIDSFEEVFSDMTVGEGEMVC 186
Cdd:pfam09741  73 NLIAQQTDYTLTCAVCTRTSPQELQPLYKVSQRVYASPSRRRMDLKGEETEITYPNICFAVDDFEETFSDVVVRDGECVC 152
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 57863295   187 VELVASDKTNTFQGVIFQGSIRYEALKKVYDNRVSVAARMAQKMSFGFYKYSNMEFVRMKGPQGKGHAEMA 257
Cdd:pfam09741 153 VELVAHDRAAFFKGVLFSGSVRYEMLRKAYDARASSAKSWAQKLLSSGGLQGRVEFVRMKGPGGKGEAEMA 223
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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