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Conserved domains on  [gi|57164960|ref|NP_001008949|]
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inositol 1,4,5-trisphosphate receptor-interacting protein-like 1 isoform 2 [Homo sapiens]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Mab-21_C super family cl48430
Mab-21 protein HhH/H2TH-like domain; This family contains Mab-21 and Mab-21 like proteins. In ...
 421-522 8.66e-05

Mab-21 protein HhH/H2TH-like domain; This family contains Mab-21 and Mab-21 like proteins. In C. elegans these proteins are required for several aspects of embryonic development.


The actual alignment was detected with superfamily member pfam20266:

Pssm-ID: 466416  Cd Length: 102  Bit Score: 41.84  E-value: 8.66e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 57164960   421 KCLQIILSLRQHQSLPHGASRPILTSYHFKTALM-HLLLRLPLTDWAHNMLSQRLQDILWFLGRGLQQRSLHHFlignnF 499
Cdd:pfam20266   4 KCLRILKKLKEPGKRDVKTELSKICSYHLKTLFLwECEKHPDDSDWDKENLSDRFLGLLEELHKCLRNGKLPHF-----F 78

                          90       100
                  ....*....|....*....|...
gi 57164960   500 LPltipipktfrnaePVNLFQHL 522
Cdd:pfam20266  79 IP-------------KLNLFQSL 88
 
Name Accession Description Interval E-value
Mab-21_C pfam20266
Mab-21 protein HhH/H2TH-like domain; This family contains Mab-21 and Mab-21 like proteins. In ...
 421-522 8.66e-05

Mab-21 protein HhH/H2TH-like domain; This family contains Mab-21 and Mab-21 like proteins. In C. elegans these proteins are required for several aspects of embryonic development.


Pssm-ID: 466416  Cd Length: 102  Bit Score: 41.84  E-value: 8.66e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 57164960   421 KCLQIILSLRQHQSLPHGASRPILTSYHFKTALM-HLLLRLPLTDWAHNMLSQRLQDILWFLGRGLQQRSLHHFlignnF 499
Cdd:pfam20266   4 KCLRILKKLKEPGKRDVKTELSKICSYHLKTLFLwECEKHPDDSDWDKENLSDRFLGLLEELHKCLRNGKLPHF-----F 78

                          90       100
                  ....*....|....*....|...
gi 57164960   500 LPltipipktfrnaePVNLFQHL 522
Cdd:pfam20266  79 IP-------------KLNLFQSL 88
 
Name Accession Description Interval E-value
Mab-21_C pfam20266
Mab-21 protein HhH/H2TH-like domain; This family contains Mab-21 and Mab-21 like proteins. In ...
 421-522 8.66e-05

Mab-21 protein HhH/H2TH-like domain; This family contains Mab-21 and Mab-21 like proteins. In C. elegans these proteins are required for several aspects of embryonic development.


Pssm-ID: 466416  Cd Length: 102  Bit Score: 41.84  E-value: 8.66e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 57164960   421 KCLQIILSLRQHQSLPHGASRPILTSYHFKTALM-HLLLRLPLTDWAHNMLSQRLQDILWFLGRGLQQRSLHHFlignnF 499
Cdd:pfam20266   4 KCLRILKKLKEPGKRDVKTELSKICSYHLKTLFLwECEKHPDDSDWDKENLSDRFLGLLEELHKCLRNGKLPHF-----F 78

                          90       100
                  ....*....|....*....|...
gi 57164960   500 LPltipipktfrnaePVNLFQHL 522
Cdd:pfam20266  79 IP-------------KLNLFQSL 88
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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