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Conserved domains on  [gi|4506643|ref|NP_000989|]
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large ribosomal subunit protein eL43 [Homo sapiens]

Protein Classification

eL43 family ribosomal protein( domain architecture ID 10015313)

eL43 family ribosomal protein is a 60S ribosomal subunit, similar to fungal 60S ribosomal protein L43 and Dictyostelium discoideum 60S ribosomal protein L37a

Gene Ontology:  GO:0006412|GO:0003735
SCOP:  4003704

Graphical summary

 Zoom to residue level

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List of domain hits

Name Accession Description Interval E-value
PTZ00255 PTZ00255
60S ribosomal protein L37a; Provisional
1-90 9.51e-45

60S ribosomal protein L37a; Provisional


:

Pssm-ID: 240332  Cd Length: 90  Bit Score: 139.07  E-value: 9.51e-45
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506643    1 MAKRTKKVGIVGKYGTRYGASLRKMVKKIEISQHAKYTCSFCGKTKMKRRAVGIWHCGSCMKTVAGGAWTYNTTSAVTVK 80
Cdd:PTZ00255  1 MAKRTKKVGITGKYGTRYGASLRKQIKKIEISQHAKYFCPFCGKHAVKRQAVGIWRCKGCKKTVAGGAWTLSTPAASTVR 80
                        90
                ....*....|
gi 4506643   81 SAIRRLKELK 90
Cdd:PTZ00255 81 STIRRLRKLK 90
 
Name Accession Description Interval E-value
PTZ00255 PTZ00255
60S ribosomal protein L37a; Provisional
1-90 9.51e-45

60S ribosomal protein L37a; Provisional


Pssm-ID: 240332  Cd Length: 90  Bit Score: 139.07  E-value: 9.51e-45
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506643    1 MAKRTKKVGIVGKYGTRYGASLRKMVKKIEISQHAKYTCSFCGKTKMKRRAVGIWHCGSCMKTVAGGAWTYNTTSAVTVK 80
Cdd:PTZ00255  1 MAKRTKKVGITGKYGTRYGASLRKQIKKIEISQHAKYFCPFCGKHAVKRQAVGIWRCKGCKKTVAGGAWTLSTPAASTVR 80
                        90
                ....*....|
gi 4506643   81 SAIRRLKELK 90
Cdd:PTZ00255 81 STIRRLRKLK 90
Ribosomal_L37ae pfam01780
Ribosomal L37ae protein family; This ribosomal protein is found in archaebacteria and ...
11-88 2.65e-44

Ribosomal L37ae protein family; This ribosomal protein is found in archaebacteria and eukaryotes. It contains four conserved cysteine residues that may bind to zinc.


Pssm-ID: 460325  Cd Length: 78  Bit Score: 137.69  E-value: 2.65e-44
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 4506643    11 VGKYGTRYGASLRKMVKKIEISQHAKYTCSFCGKTKMKRRAVGIWHCGSCMKTVAGGAWTYNTTSAVTVKSAIRRLKE 88
Cdd:pfam01780  1 AGKYGTRYGASLRKMVKKIEISQHAKYTCPFCGKTKVKRVAVGIWHCKKCGKTFAGGAYTPTTPSAVTVKSAIRRLKE 78
eL43_euk_arch TIGR00280
ribosomal protein eL43; This model finds eukaryotic ribosomal protein eL43 (previously L37a) ...
1-92 3.89e-28

ribosomal protein eL43; This model finds eukaryotic ribosomal protein eL43 (previously L37a) and its archaeal orthologs. The nomeclature is tricky because eukaryotes have proteins called both L37 and L37a. [Protein synthesis, Ribosomal proteins: synthesis and modification]


Pssm-ID: 272996  Cd Length: 92  Bit Score: 97.25  E-value: 3.89e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506643     1 MAKRTKKVGIVGKYGTRYGASLRKMVKKIEISQHAKYTCSFCGKTKMKRRAVGIWHCGSCMKTVAGGAWTYNTTSAVTVK 80
Cdd:TIGR00280  1 MMKRTKKVGITGRFGPRYGLKLRRQVKKIEIQQKAKYVCPFCGKKTVKRGSTGIWTCRKCGAKFAGGAYTPVTPAGKTVR 80
                         90
                 ....*....|..
gi 4506643    81 SAIRRLKELKDQ 92
Cdd:TIGR00280 81 KTIRRIVEMKEA 92
RPL43A COG1997
Ribosomal protein L37AE/L43A [Translation, ribosomal structure and biogenesis]; Ribosomal ...
1-86 2.30e-25

Ribosomal protein L37AE/L43A [Translation, ribosomal structure and biogenesis]; Ribosomal protein L37AE/L43A is part of the Pathway/BioSystem: Archaeal ribosomal proteins


Pssm-ID: 441600  Cd Length: 87  Bit Score: 89.99  E-value: 2.30e-25
                       10        20        30        40        50        60        70        80
               ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506643   1 MAKRTKKVGIVGKYGTRYGASLRKMVKKIEISQHAKYTCSFCGKTKMKRRAVGIWHCGSCMKTVAGGAWTYNTTSAVTVK 80
Cdd:COG1997  1 MMKKTKKVGSAGRFGPRYGRKLRKRVADIEEKMRAKHTCPECGSKRVKRVATGIWECRKCGYKFAGGAYVPETPAGKTVG 80

               ....*.
gi 4506643  81 SAIRRL 86
Cdd:COG1997 81 RAIKRA 86
 
Name Accession Description Interval E-value
PTZ00255 PTZ00255
60S ribosomal protein L37a; Provisional
1-90 9.51e-45

60S ribosomal protein L37a; Provisional


Pssm-ID: 240332  Cd Length: 90  Bit Score: 139.07  E-value: 9.51e-45
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506643    1 MAKRTKKVGIVGKYGTRYGASLRKMVKKIEISQHAKYTCSFCGKTKMKRRAVGIWHCGSCMKTVAGGAWTYNTTSAVTVK 80
Cdd:PTZ00255  1 MAKRTKKVGITGKYGTRYGASLRKQIKKIEISQHAKYFCPFCGKHAVKRQAVGIWRCKGCKKTVAGGAWTLSTPAASTVR 80
                        90
                ....*....|
gi 4506643   81 SAIRRLKELK 90
Cdd:PTZ00255 81 STIRRLRKLK 90
Ribosomal_L37ae pfam01780
Ribosomal L37ae protein family; This ribosomal protein is found in archaebacteria and ...
11-88 2.65e-44

Ribosomal L37ae protein family; This ribosomal protein is found in archaebacteria and eukaryotes. It contains four conserved cysteine residues that may bind to zinc.


Pssm-ID: 460325  Cd Length: 78  Bit Score: 137.69  E-value: 2.65e-44
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 4506643    11 VGKYGTRYGASLRKMVKKIEISQHAKYTCSFCGKTKMKRRAVGIWHCGSCMKTVAGGAWTYNTTSAVTVKSAIRRLKE 88
Cdd:pfam01780  1 AGKYGTRYGASLRKMVKKIEISQHAKYTCPFCGKTKVKRVAVGIWHCKKCGKTFAGGAYTPTTPSAVTVKSAIRRLKE 78
eL43_euk_arch TIGR00280
ribosomal protein eL43; This model finds eukaryotic ribosomal protein eL43 (previously L37a) ...
1-92 3.89e-28

ribosomal protein eL43; This model finds eukaryotic ribosomal protein eL43 (previously L37a) and its archaeal orthologs. The nomeclature is tricky because eukaryotes have proteins called both L37 and L37a. [Protein synthesis, Ribosomal proteins: synthesis and modification]


Pssm-ID: 272996  Cd Length: 92  Bit Score: 97.25  E-value: 3.89e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506643     1 MAKRTKKVGIVGKYGTRYGASLRKMVKKIEISQHAKYTCSFCGKTKMKRRAVGIWHCGSCMKTVAGGAWTYNTTSAVTVK 80
Cdd:TIGR00280  1 MMKRTKKVGITGRFGPRYGLKLRRQVKKIEIQQKAKYVCPFCGKKTVKRGSTGIWTCRKCGAKFAGGAYTPVTPAGKTVR 80
                         90
                 ....*....|..
gi 4506643    81 SAIRRLKELKDQ 92
Cdd:TIGR00280 81 KTIRRIVEMKEA 92
rpl37ae PRK03976
50S ribosomal protein L37Ae; Reviewed
1-90 1.30e-27

50S ribosomal protein L37Ae; Reviewed


Pssm-ID: 235183  Cd Length: 90  Bit Score: 95.81  E-value: 1.30e-27
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506643    1 MAKRTKKVGIVGKYGTRYGASLRKMVKKIEISQHAKYTCSFCGKTKMKRRAVGIWHCGSCMKTVAGGAWTYNTTSAVTVK 80
Cdd:PRK03976  1 MMSRTKKVGSAGRFGARYGRKIRKRVADIEEKMRAKHVCPVCGRPKVKRVGTGIWECRKCGAKFAGGAYTPETPAGKTVT 80
                        90
                ....*....|
gi 4506643   81 SAIRRLKELK 90
Cdd:PRK03976 81 RAIRRAVEEK 90
RPL43A COG1997
Ribosomal protein L37AE/L43A [Translation, ribosomal structure and biogenesis]; Ribosomal ...
1-86 2.30e-25

Ribosomal protein L37AE/L43A [Translation, ribosomal structure and biogenesis]; Ribosomal protein L37AE/L43A is part of the Pathway/BioSystem: Archaeal ribosomal proteins


Pssm-ID: 441600  Cd Length: 87  Bit Score: 89.99  E-value: 2.30e-25
                       10        20        30        40        50        60        70        80
               ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506643   1 MAKRTKKVGIVGKYGTRYGASLRKMVKKIEISQHAKYTCSFCGKTKMKRRAVGIWHCGSCMKTVAGGAWTYNTTSAVTVK 80
Cdd:COG1997  1 MMKKTKKVGSAGRFGPRYGRKLRKRVADIEEKMRAKHTCPECGSKRVKRVATGIWECRKCGYKFAGGAYVPETPAGKTVG 80

               ....*.
gi 4506643  81 SAIRRL 86
Cdd:COG1997 81 RAIKRA 86
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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