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Conserved domains on  [gi|99030225|gb|ABF61382|]
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NADH dehydrogenase subunit 2, partial (mitochondrion) [Micropsitta finschii]

Protein Classification

NADH dehydrogenase subunit 2( domain architecture ID 11475904)

NADH dehydrogenase subunit 2 is the core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), which functions in the transfer of electrons from NADH to the respiratory chain

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ND2 MTH00112
NADH dehydrogenase subunit 2; Provisional
 1-273 7.90e-122

NADH dehydrogenase subunit 2; Provisional


:

Pssm-ID: 214423 [Multi-domain]  Cd Length: 346  Bit Score: 351.43  E-value: 7.90e-122
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 99030225    1 PLTKFISTTSLLLGTTITITSNHWMMAWTGLEINTLAIIPHISKSHHPRSIEATTKYFLVQATASALMLFSSMINAQLTG 80
Cdd:MTH00112   3 PHAKLIITTSLILGTIITISSNHWLMAWTGLEINTLAIIPLISKPHHPRATEAATKYFLTQAAASALILFSSTTNAWNTG 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 99030225   81 QWDITQLTYPPSCLLLTTAIAIKLGLAPFHFWFPDVLQGSPLTTALLLSTLMKLPPTTILLLTSHSLNPTLLTTMSITSI 160
Cdd:MTH00112  83 QWDITQLTNPTSCTLLTLALAMKLGLAPFHFWLPEVLQGSTTTTALILSTWQKLAPLTLLLMTSNSLNPTLLLTLAILST 162

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 99030225  161 A*GGWMGLNQTQTRKILAFSSISHLGWMTIITTYNPKLTLLTFYTYTLMTTSIFLTMNTTNTLKLPTLMTSWTKMPTLNT 240
Cdd:MTH00112 163 LIGGWGGLNQTQLRKIMAFSSIAHLGWMIAIITYSPKLTLLTFYIYILMTTPMFLTLNTTSTKTLKDMMTSWTKSPTLNT 242

                        250       260       270
                 ....*....|....*....|....*....|...
gi 99030225  241 TLMLTLLSLAGLPPLTGFLPKWLIIQELTKQEM 273
Cdd:MTH00112 243 TLMLTLLSLAGLPPLTGFMPKWLILQELTKQNM 275
 
Name Accession Description Interval E-value
ND2 MTH00112
NADH dehydrogenase subunit 2; Provisional
 1-273 7.90e-122

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214423 [Multi-domain]  Cd Length: 346  Bit Score: 351.43  E-value: 7.90e-122
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 99030225    1 PLTKFISTTSLLLGTTITITSNHWMMAWTGLEINTLAIIPHISKSHHPRSIEATTKYFLVQATASALMLFSSMINAQLTG 80
Cdd:MTH00112   3 PHAKLIITTSLILGTIITISSNHWLMAWTGLEINTLAIIPLISKPHHPRATEAATKYFLTQAAASALILFSSTTNAWNTG 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 99030225   81 QWDITQLTYPPSCLLLTTAIAIKLGLAPFHFWFPDVLQGSPLTTALLLSTLMKLPPTTILLLTSHSLNPTLLTTMSITSI 160
Cdd:MTH00112  83 QWDITQLTNPTSCTLLTLALAMKLGLAPFHFWLPEVLQGSTTTTALILSTWQKLAPLTLLLMTSNSLNPTLLLTLAILST 162

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 99030225  161 A*GGWMGLNQTQTRKILAFSSISHLGWMTIITTYNPKLTLLTFYTYTLMTTSIFLTMNTTNTLKLPTLMTSWTKMPTLNT 240
Cdd:MTH00112 163 LIGGWGGLNQTQLRKIMAFSSIAHLGWMIAIITYSPKLTLLTFYIYILMTTPMFLTLNTTSTKTLKDMMTSWTKSPTLNT 242

                        250       260       270
                 ....*....|....*....|....*....|...
gi 99030225  241 TLMLTLLSLAGLPPLTGFLPKWLIIQELTKQEM 273
Cdd:MTH00112 243 TLMLTLLSLAGLPPLTGFMPKWLILQELTKQNM 275
Proton_antipo_M pfam00361
Proton-conducting membrane transporter; This is a family of membrane transporters that ...
 21-266 5.85e-24

Proton-conducting membrane transporter; This is a family of membrane transporters that inlcudes some 7 of potentially 14-16 TM regions. In many instances the family forms part of complex I that catalyzes the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane, and in this context is a combination predominantly of subunits 2, 4, 5, 14, L, M and N. In many bacterial species these proteins are probable stand-alone transporters not coupled with oxidoreduction. The family in total represents homologs across the phyla.


Pssm-ID: 425636 [Multi-domain]  Cd Length: 291  Bit Score: 97.77  E-value: 5.85e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 99030225    21 SNHWMMAWTGLEINTLAIIPHI-SKSHHPRSIEATTKYFLVQATASALMLFSSMINAQLTGQWDITQL-TYPPSC----- 93
Cdd:pfam00361   1 ANDLLLMYLGWEAVLLPSYLLIgYWGKSPRSSEAGMKYFLLTLLGSSILLFGISLMYNYTGTLSFDELsKALTGGlnssg 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 99030225    94 -----LLLTTAIAIKLGLAPFHFWFPDVLQGSPLTTALLLSTLM-KLPPTTILLLTS--HSLNPT---LLTTMSITSIA* 162
Cdd:pfam00361  81 llllfLLILVGFLFKSAQVPFHTWLPDAYEGAPTPVSALLAATLvKAGGYGLIRRSLlyLPSSPFiqqILLILAIISMLL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 99030225   163 GGWMGLNQTQTRKILAFSSISHLGWMTII----TTYNPKLTLLTFYTYTLMTTSIFL--------TMNTTNTLKLPTLmt 230
Cdd:pfam00361 161 GSLAALVQTDIKRLLAYSSISHMGYMLIAlgagTIYGIQAAIFHLLTHGLFSAGLFLcagsviyrRVHTRNIRDYGGL-- 238

                         250       260       270
                  ....*....|....*....|....*....|....*.
gi 99030225   231 sWTKMPTLNTTLMLTLLSLAGLPPLTGFLPKWLIIQ 266
Cdd:pfam00361 239 -AKTMPILALVFLVAMLSLAGLPPTAGFLGKFLILA 273
NuoN COG1007
NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH: ...
 12-268 1.21e-21

NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 2 (chain N) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440631 [Multi-domain]  Cd Length: 473  Bit Score: 93.64  E-value: 1.21e-21
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 99030225  12 LLGTTITITSNHWMMAWTGLEINTLA--IIPHISKsHHPRSIEATTKYFLVQATASALMLF-SSMINAqLTGQWDITQL- 87
Cdd:COG1007 112 TLGMMLMASANDLLTLFLGLELLSLSlyVLVAFRR-DDRRSSEAALKYFLLGALSSGFLLYgISLLYG-ATGSLNLAGIa 189

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 99030225  88 -------TYPP----SCLLLTTAIAIKLGLAPFHFWFPDVLQGSPlttalllstlmklPPTT-----------------I 139
Cdd:COG1007 190 aalaaggANSPllllGLVLVLAGLAFKLSAVPFHMWTPDVYEGAP-------------TPVTaflatapkiaafaallrL 256

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 99030225 140 LLLTSHSLNP---TLLTTMSITSIA*GGWMGLNQTQTRKILAFSSISHLGWMTI-ITTYNPK-LTLLTFY--TYTLMTTS 212
Cdd:COG1007 257 LVEAFPGLAAdwqLLLAVLAVLSMTVGNLAALAQTNVKRMLAYSSIAHAGYLLLgLAAGTPLgVSAALFYllAYLFMNLG 336

                       250       260       270       280       290       300
                ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 99030225 213 IFLTMNTTNTLKLPTLMTS-----WTKMPTLNTTLMLTLLSLAGLPPLTGFLPKWLIIQEL 268
Cdd:COG1007 337 AFAVILLLSRKGGEAEEIEdlaglARRSPLLALAMTIFLLSLAGIPPTAGFFGKFYVFSAA 397
NDH_I_N TIGR01770
proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th ...
 12-273 6.93e-16

proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th (based on E. coli) structural gene, N, of bacterial and chloroplast energy-transducing NADH (or NADPH) dehydrogenases. This model does not describe any subunit of the mitochondrial complex I (for which the subunit composition is very different), nor NADH dehydrogenases that are not coupled to ion transport. The Enzyme Commission designation 1.6.5.3, for NADH dehydrogenase (ubiquinone), is applied broadly, perhaps unfortunately, even if the quinone is menaquinone (Thermus, Mycobacterium) or plastoquinone (chloroplast). For chloroplast members, the name NADH-plastoquinone oxidoreductase is used for the complex and this protein is designated as subunit 2 or B. This model also includes a subunit of a related complex in the archaeal methanogen, Methanosarcina mazei, in which F420H2 replaces NADH and 2-hydroxyphenazine replaces the quinone. [Energy metabolism, Electron transport]


Pssm-ID: 273795 [Multi-domain]  Cd Length: 468  Bit Score: 76.91  E-value: 6.93e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 99030225    12 LLGTTITITSNHWMMAWTGLEINTLAI-IPHISKSHHPRSIEATTKYFLVQATASALMLFSSMINAQLTGQWDITQLTYP 90
Cdd:TIGR01770 112 LLGIFLLVSSNDLLSIYLGLELQSLCFyVLAGLKRKSRFSTEAGLKYFILGAFSSGLLLFGISLIYGFTGSLNFEDLLLF 191

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 99030225    91 PSC------------LLLTTAIAIKLGLAPFHFWFPDVLQGSPLTTALLLSTLMKLPPTTILL-------LTSHSLNPTL 151
Cdd:TIGR01770 192 LSNgmlnisllllgiVLILVGLLFKLSAVPFHMWVPDVYEGAPTPVTAFFSIVPKIAIFAVFLrlflyilFGFSEAWQIF 271

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 99030225   152 LTTMSITSIA*GGWMGLNQTQTRKILAFSSISHLGW----MTIITTYNPKLTLLTFYTYTLMTTSIFLTMNTTNTLKLP- 226
Cdd:TIGR01770 272 LAIIAFLSMLIGNFGALAQKKVKRLLAYSSISHVGYiligLLAGTLEGIKAVLFYIFIYALMSLGAFGVLSLLRSYKDEw 351

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|..
gi 99030225   227 ----TLMTSWTKM-PTLNTTLMLTLLSLAGLPPLTGFLPKWLIIQELTKQEM 273
Cdd:TIGR01770 352 ieyiSDFAGLFKTnPILAILILIFMFSLAGIPPLAGFFGKFYVFFALLKSGL 403
 
Name Accession Description Interval E-value
ND2 MTH00112
NADH dehydrogenase subunit 2; Provisional
 1-273 7.90e-122

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214423 [Multi-domain]  Cd Length: 346  Bit Score: 351.43  E-value: 7.90e-122
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 99030225    1 PLTKFISTTSLLLGTTITITSNHWMMAWTGLEINTLAIIPHISKSHHPRSIEATTKYFLVQATASALMLFSSMINAQLTG 80
Cdd:MTH00112   3 PHAKLIITTSLILGTIITISSNHWLMAWTGLEINTLAIIPLISKPHHPRATEAATKYFLTQAAASALILFSSTTNAWNTG 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 99030225   81 QWDITQLTYPPSCLLLTTAIAIKLGLAPFHFWFPDVLQGSPLTTALLLSTLMKLPPTTILLLTSHSLNPTLLTTMSITSI 160
Cdd:MTH00112  83 QWDITQLTNPTSCTLLTLALAMKLGLAPFHFWLPEVLQGSTTTTALILSTWQKLAPLTLLLMTSNSLNPTLLLTLAILST 162

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 99030225  161 A*GGWMGLNQTQTRKILAFSSISHLGWMTIITTYNPKLTLLTFYTYTLMTTSIFLTMNTTNTLKLPTLMTSWTKMPTLNT 240
Cdd:MTH00112 163 LIGGWGGLNQTQLRKIMAFSSIAHLGWMIAIITYSPKLTLLTFYIYILMTTPMFLTLNTTSTKTLKDMMTSWTKSPTLNT 242

                        250       260       270
                 ....*....|....*....|....*....|...
gi 99030225  241 TLMLTLLSLAGLPPLTGFLPKWLIIQELTKQEM 273
Cdd:MTH00112 243 TLMLTLLSLAGLPPLTGFMPKWLILQELTKQNM 275
ND2 MTH00135
NADH dehydrogenase subunit 2; Provisional
 10-273 6.40e-104

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177193 [Multi-domain]  Cd Length: 347  Bit Score: 305.96  E-value: 6.40e-104
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 99030225   10 SLLLGTTITITSNHWMMAWTGLEINTLAIIPHISKSHHPRSIEATTKYFLVQATASALMLFSSMINAQLTGQWDITQLTY 89
Cdd:MTH00135  12 SLGLGTTLTFASSHWLLAWMGLEINTLAIIPLMAQHHHPRAVEATTKYFLTQATAAAMILFASTTNAWLTGQWDIQQMSH 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 99030225   90 PPSCLLLTTAIAIKLGLAPFHFWFPDVLQGSPLTTALLLSTLMKLPPTtILLLTSHSLNPTLLTTMSITSIA*GGWMGLN 169
Cdd:MTH00135  92 PLPTTMITLALALKIGLAPLHFWLPEVLQGLDLTTGLILSTWQKLAPF-ALILQIAPTNPTLLITLGLTSTLVGGWGGLN 170

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 99030225  170 QTQTRKILAFSSISHLGWMTIITTYNPKLTLLTFYTYTLMTTSIFLTMNTTNTLKLPTLMTSWTKMPTLNTTLMLTLLSL 249
Cdd:MTH00135 171 QTQLRKILAYSSIAHLGWMILVLQFSPSLTLLALLTYIIMTSSAFLTFKLNSSTKINTLATSWTKAPALTALTPLILLSL 250

                        250       260
                 ....*....|....*....|....
gi 99030225  250 AGLPPLTGFLPKWLIIQELTKQEM 273
Cdd:MTH00135 251 GGLPPLTGFMPKWLILQELTKQDL 274
ND2 MTH00070
NADH dehydrogenase subunit 2; Provisional
 1-273 4.52e-102

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177142 [Multi-domain]  Cd Length: 346  Bit Score: 301.07  E-value: 4.52e-102
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 99030225    1 PLTKFISTTSLLLGTTITITSNHWMMAWTGLEINTLAIIPHISKSHHPRSIEATTKYFLVQATASALMLFSSMINAQLTG 80
Cdd:MTH00070   3 PYALSILLSSLALGTMITLSSNHWFLAWMGLEINTLAIIPLMTKTHHPRATEAATKYFLTQASASALILFSSTINAWFTG 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 99030225   81 QWDITQLTYPPSCLLLTTAIAIKLGLAPFHFWFPDVLQGSPLTTALLLSTLMKLPPTTILLLTSHSLNPTLLTTMSITSI 160
Cdd:MTH00070  83 EWTIMNMQTPLPTIMLTIALMMKLGIAPFHFWLPEVLQGLDLTTGLILSTWQKLAPMALLIQISHLLNSNLLIIMGLLST 162

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 99030225  161 A*GGWMGLNQTQTRKILAFSSISHLGWMTIITTYNPKLTLLTFYTYTLMTTSIFLTMNTTNTLKLPTLMTSWTKMPTLNT 240
Cdd:MTH00070 163 LIGGWGGLNQTQLRKIMAYSSIAHLGWMIIILTFSPHLTLLNLLIYLIMTSSMFLMLMNLNSTNINKLSSSWSKNPTLTS 242

                        250       260       270
                 ....*....|....*....|....*....|...
gi 99030225  241 TLMLTLLSLAGLPPLTGFLPKWLIIQELTKQEM 273
Cdd:MTH00070 243 MMMLTLLSLGGLPPTTGFIPKWLILQELTKQNL 275
ND2 MTH00105
NADH dehydrogenase subunit 2; Provisional
 1-273 2.86e-94

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177167 [Multi-domain]  Cd Length: 347  Bit Score: 281.35  E-value: 2.86e-94
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 99030225    1 PLTKFISTTSLLLGTTITITSNHWMMAWTGLEINTLAIIPHISKSHHPRSIEATTKYFLVQATASALMLFSSMINAQLTG 80
Cdd:MTH00105   3 PLILIIIYLTLFLGTMITMISSHWLLAWIGLEMNMLAIIPILMKKHNPRSTEAATKYFLTQATASMLLMMAIIINLMYSG 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 99030225   81 QWDITQLTYPPSCLLLTTAIAIKLGLAPFHFWFPDVLQGSPLTTALLLSTLMKLPPTTILLLTSHSLNPTLLTTMSITSI 160
Cdd:MTH00105  83 QWTITKLTNPTASTLMTIALAMKLGLAPFHFWVPEVTQGIPLSSGMILLTWQKLAPLSILYQISPSINPNLLLTLAILSI 162

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 99030225  161 A*GGWMGLNQTQTRKILAFSSISHLGWMTIITTYNPKLTLLTFYTYTLMTTSIFLTMNTTNTLKLPTLMTSWTKMPTLNT 240
Cdd:MTH00105 163 LIGGWGGLNQTQLRKILAYSSIAHMGWMTAILPYNPTLTLLNLLIYIIMTLTMFMLLMLNSSTTTLSLSHTWNKTPLMTS 242

                        250       260       270
                 ....*....|....*....|....*....|...
gi 99030225  241 TLMLTLLSLAGLPPLTGFLPKWLIIQELTKQEM 273
Cdd:MTH00105 243 LILLTLLSLGGLPPLTGFMPKWMIIQELTKNNN 275
ND2 MTH00041
NADH dehydrogenase subunit 2; Validated
 9-265 5.10e-77

NADH dehydrogenase subunit 2; Validated


Pssm-ID: 177116 [Multi-domain]  Cd Length: 349  Bit Score: 237.52  E-value: 5.10e-77
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 99030225    9 TSLLLGTTITITSNHWMMAWTGLEINTLAIIPHISKSHHPRSIEATTKYFLVQATASALMLFSSMINAQLTGQWDITQLT 88
Cdd:MTH00041  11 TSIILGTIIVISSNHWFLIWLGLELNTLSIIPILSSNFSPRSVEATIKYFLVQAFSAAILLNGALIQAWLSGSWSINGPL 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 99030225   89 YPPSCLLLTTAIAIKLGLAPFHFWFPDVLQGSPLTTALLLSTLMKLPPTTILLLTSHSLNPTLLTTMSITSIA*GGWMGL 168
Cdd:MTH00041  91 NTLSSIIITLALALKLGLAPCHFWFPDVLQGLPFLQGLIIATWQKIAPLILLISISNLLNSNILILCGILSVLVGGWGGL 170

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 99030225  169 NQTQTRKILAFSSISHLGWMTIITTYNPKLTLLTFYTYTLMTTSIFLTMNTTNTLKLPTLMTSWTKMPTLNTTLMLTLLS 248
Cdd:MTH00041 171 NQTQTRKILAFSSIAHLGWIIITSAYSPNASIIMFLIYIIINTSIFLIGNNFSLSTLSHLNKLSQLNPISAFLFILSILS 250

                        250
                 ....*....|....*..
gi 99030225  249 LAGLPPLTGFLPKWLII 265
Cdd:MTH00041 251 LGGLPPLTGFLNKFISL 267
ND2 MTH00200
NADH dehydrogenase subunit 2; Provisional
 1-273 1.41e-76

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177246 [Multi-domain]  Cd Length: 347  Bit Score: 236.40  E-value: 1.41e-76
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 99030225    1 PLTKFISTTSLLLGTTITITSNHWMMAWTGLEINTLAIIPHISKSHHPRSIEATTKYFLVQATASALMLFSSMINAQLTG 80
Cdd:MTH00200   3 PLILPLFILSLGLGTLLTFSSSHWFLIWLGLEINTLAIIPLLIKQHHPRKVEATTKYFIIQATASALLLFGGLLNAWTSG 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 99030225   81 QWDITQLTYPPSCLLLTTAIAIKLGLAPFHFWFPDVLQGSPLTTALLLSTLMKLPPTTILLLTSHSLNPTLLTTMSITSI 160
Cdd:MTH00200  83 QWGISEMLGPLSETLILLALALKLGLAPGHFWVPDVLQGLSLQTGLILSTWQKLAPFALLIQLAPALNSNILLLLGLLSV 162

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 99030225  161 A*GGWMGLNQTQTRKILAFSSISHLGWMTIITTYNPKLTLLTFYTYTLMTTSIFLTMNTTNTLKLPTLMTSWTKMPTLNT 240
Cdd:MTH00200 163 LVGGWGGLNQTQLRKILAYSSIAHLGWLLSGLVYSPNLALLYLLLYVIITLTVFLLLNLLNSTKINSLSSSKTKNPILSM 242

                        250       260       270
                 ....*....|....*....|....*....|...
gi 99030225  241 TLMLTLLSLAGLPPLTGFLPKWLIIQELTKQEM 273
Cdd:MTH00200 243 LLGLTLLSLGGLPPLTGFFPKWLILQELSKQGL 275
ND2 MTH00160
NADH dehydrogenase subunit 2; Provisional
 2-273 5.28e-49

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214442 [Multi-domain]  Cd Length: 335  Bit Score: 165.00  E-value: 5.28e-49
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 99030225    2 LTKFISTTSLLLGTTITITSNHWMMAWTGLEINTLAIIPHISKSHHPRSIEATTKYFLVQATASALMLFSSMINAQLTGq 81
Cdd:MTH00160   5 SSKLLFLSTLIMGTLISISSNSWFGAWMGLEINLLSFIPLISNKKNLMSSESSLKYFLIQALASIILLFSIILNMLNLM- 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 99030225   82 wditqLTYPPSCLLLTTAIAIKLGLAPFHFWFPDVLQGSPLTTALLLSTLMKLPPttiLLLTSHSLNPTLLTTMSITSIA 161
Cdd:MTH00160  84 -----LFNNISSMLINSSLLLKLGAAPFHFWFPEVMEGLSWINCFILMTWQKIAP---LILLSYLINNNFIIIIIILSAI 155

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 99030225  162 *GGWMGLNQTQTRKILAFSSISHLGWMTIITTYNPKLTLLTFYTYTLMTTSIFLTMNTTNTLKLPTLMTSWTKMPTLNTT 241
Cdd:MTH00160 156 IGAIGGLNQTSLRKILAYSSINHLGWMLSSMMISENLWLIYFLIYSIISLSIILLFNKFNIFFLNQLFNSNNKSKKIKFL 235

                        250       260       270
                 ....*....|....*....|....*....|..
gi 99030225  242 LMLTLLSLAGLPPLTGFLPKWLIIQELTKQEM 273
Cdd:MTH00160 236 LFLNLLSLGGLPPFLGFLPKWIIIQLLISNNM 267
ND2 MTH00144
NADH dehydrogenase subunit 2; Provisional
 11-273 5.31e-42

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214432 [Multi-domain]  Cd Length: 328  Bit Score: 146.57  E-value: 5.31e-42
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 99030225   11 LLLGTTITITSNHWMMAWTGLEINTLAIIPHISKSHHPRSIEATTKYFLVQATASALMLFSSMINAQLTGQWDITqltyp 90
Cdd:MTH00144  13 MVMGTLLSLSSSHWLGVWVGLEINLIGFLPLLVYKKKSSESESVVKYFIIQSLGSSLLIFGSLIMYNLSFSWFSM----- 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 99030225   91 pscLLLTTAIAIKLGLAPFHFWFPDVLQGSPLTTALLLSTLMKLPPttILLLTSHSLNPTLLTT---MSITSIA*GGWMG 167
Cdd:MTH00144  88 ---SLLLLGLCLKLGLFPFHFWVPSVMAGLSWLSCFLLLTWQKVAP--LFLLSNFLDLYWLAYLlcvISVLSALVGSIGG 162

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 99030225  168 LNQTQTRKILAFSSISHLGWMTIITTYNPKLTLLTFYTYTLMTTSIFLTMNTTNTlKLPTLMTSWTKMPTLNTTLMLTLL 247
Cdd:MTH00144 163 LNQTQVRALLAYSSISHTGWMLVAILHGSWLMWMYFLIYIVSSGFLFFSLWSGDS-GSMKDLGSLKPSYKTGLSIISLLL 241

                        250       260
                 ....*....|....*....|....*.
gi 99030225  248 SLAGLPPLTGFLPKWLIIQELTKQEM 273
Cdd:MTH00144 242 SLGGLPPFLGFCSKLLVLISSMESSP 267
ND2 MTH00011
NADH dehydrogenase subunit 2; Validated
 3-273 8.29e-42

NADH dehydrogenase subunit 2; Validated


Pssm-ID: 164587 [Multi-domain]  Cd Length: 330  Bit Score: 146.08  E-value: 8.29e-42
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 99030225    3 TKFISTTSLLLGTTITITSNHWMMAWTGLEINTLAIIPHISKSHHPRSIEATTKYFLVQATASALMLFSSminaqlTGQW 82
Cdd:MTH00011   7 TMFLFSSTMTLGTLMALSSNNWLFLWMGMELNLLSFVPLMTSSKMNQESEAAVKYFLAQALGSGLLLLGM------TMMW 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 99030225   83 DITQLTYPPSCLLLTTAIAIKLGLAPFHFWFPDVLQGSPLTTALLLSTLMKLPPTTILLLTSHSLNPTLLTTMSITSIA* 162
Cdd:MTH00011  81 SFPSLLKNITALMLLVSLMLKLGMAPCHFWFPSVMSSISWTLCLILSTWQKIAPLSILFFFTSHNILPMMTSMAAMSALA 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 99030225  163 GGWMGLNQTQTRKILAFSSISHLGWMTIITTYNPKLTLLTFYTYTLMTTSIFLTMNTTNTLKLPTLMTSWTKMPTLNTTL 242
Cdd:MTH00011 161 GGLGGMNQTQLRPLLAYSSIGHMGWMTMISVFSPSMAILYFMTYIIITTPLMLLFAYLNAFSTKFNSKISSMSQTTSMSL 240

                        250       260       270
                 ....*....|....*....|....*....|.
gi 99030225  243 MLTLLSLAGLPPLTGFLPKWLIIQELTKQEM 273
Cdd:MTH00011 241 FIMLLSLGGLPPFTGFMPKLMAIETLTSNSM 271
ND2 MTH00197
NADH dehydrogenase subunit 2; Provisional
 5-268 1.10e-35

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177244 [Multi-domain]  Cd Length: 323  Bit Score: 129.79  E-value: 1.10e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 99030225    5 FISTTSLLLGTTITITSNHWMMAWTGLEINTLAIIPHISKSHHPRSIEATTKYFLVQATASALMLFSSMINAqltgqwdI 84
Cdd:MTH00197   1 FLFLFIIFGGVLFSLSSSNWFLVWIGMELNLIGFIPLLSQNKSITENEGAMKYFLFQEFGSALLLMGGSLSF-------S 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 99030225   85 TQLTYPPSCLLLTTAIAIKLGLAPFHFWFPDVLQGSPLTTALLLSTLMKLPPttILLLTSHSLNPTLLTTMSITSIA*GG 164
Cdd:MTH00197  74 NLYLSLLSVVLVILGLLLKLGAFPFHFWVPSVMESLSWFNCFLLATWQKLAP--LLILAFNSSSFMGLLICSVLSSLIGG 151

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 99030225  165 WMGLNQTQTRKILAFSSISHLGWMTIITTYNPKLTLLTFYTYTLMTTSIFLTMNTTNTLKLPTLMTSWTKMPTLNTTLML 244
Cdd:MTH00197 152 IGGMNQSNIRQLLAYSSIGHTGWMLMSLVYSPSIFMLYYLIYFVIMFMLFLFLSKNNLSSLNQQYSNPESMSSNLVFLGL 231

                        250       260
                 ....*....|....*....|....
gi 99030225  245 TLLSLAGLPPLTGFLPKWLIIQEL 268
Cdd:MTH00197 232 SFLSLGGLPPLSGFFLKWLILTSL 255
ND2 MTH00196
NADH dehydrogenase subunit 2; Provisional
 11-265 8.73e-25

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214453 [Multi-domain]  Cd Length: 365  Bit Score: 101.26  E-value: 8.73e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 99030225   11 LLLGTTITITSNHWMMAWTGLEINTLAIIPHI-SKSHHPRSIEATTKYFLVQATASALMLFS-------------SMINA 76
Cdd:MTH00196   2 VALGILCLISSSNWLSVYLAIELQTLSLFILIaQNRGSGYSAEAGLKYFVLGALSSGLFLFGcallcgttgglhlSYINL 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 99030225   77 QLTGQWDITQLTYPPSCLLLTTAIAIKLGLAPFHFWFPDVLQGSPLTTALLLSTLMKLPPTTILLltSHSLNPTLLTTMS 156
Cdd:MTH00196  82 VLNSGQSFSSVSVPIGYLLIIVALLFKLSVAPFHMWAPDVYEGAPTKTTALLAIVPKLGIFSILV--SIGLNVNILLIGG 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 99030225  157 ITSIA*GGWMGLNQTQTRKILAFSSISHLGWMTIITTYNP----KLTLLTFYTYTLMTTSIFLTMNTTNTLKLPTLMTSW 232
Cdd:MTH00196 160 LFSLFVGAIGALNQTKIKRLLAYSGIGHMGFVLWGIEIGSfesiQASLVYLFIYIIMSICVFSIILALNVYKNLIIEFSG 239

                        250       260       270
                 ....*....|....*....|....*....|....*
gi 99030225  233 TKM--PTLNTTLMLTLLSLAGLPPLTGFLPKWLII 265
Cdd:MTH00196 240 LSRrlPILAITLALTFLSIAGIPPLVGFLGKWLIL 274
Proton_antipo_M pfam00361
Proton-conducting membrane transporter; This is a family of membrane transporters that ...
 21-266 5.85e-24

Proton-conducting membrane transporter; This is a family of membrane transporters that inlcudes some 7 of potentially 14-16 TM regions. In many instances the family forms part of complex I that catalyzes the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane, and in this context is a combination predominantly of subunits 2, 4, 5, 14, L, M and N. In many bacterial species these proteins are probable stand-alone transporters not coupled with oxidoreduction. The family in total represents homologs across the phyla.


Pssm-ID: 425636 [Multi-domain]  Cd Length: 291  Bit Score: 97.77  E-value: 5.85e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 99030225    21 SNHWMMAWTGLEINTLAIIPHI-SKSHHPRSIEATTKYFLVQATASALMLFSSMINAQLTGQWDITQL-TYPPSC----- 93
Cdd:pfam00361   1 ANDLLLMYLGWEAVLLPSYLLIgYWGKSPRSSEAGMKYFLLTLLGSSILLFGISLMYNYTGTLSFDELsKALTGGlnssg 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 99030225    94 -----LLLTTAIAIKLGLAPFHFWFPDVLQGSPLTTALLLSTLM-KLPPTTILLLTS--HSLNPT---LLTTMSITSIA* 162
Cdd:pfam00361  81 llllfLLILVGFLFKSAQVPFHTWLPDAYEGAPTPVSALLAATLvKAGGYGLIRRSLlyLPSSPFiqqILLILAIISMLL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 99030225   163 GGWMGLNQTQTRKILAFSSISHLGWMTII----TTYNPKLTLLTFYTYTLMTTSIFL--------TMNTTNTLKLPTLmt 230
Cdd:pfam00361 161 GSLAALVQTDIKRLLAYSSISHMGYMLIAlgagTIYGIQAAIFHLLTHGLFSAGLFLcagsviyrRVHTRNIRDYGGL-- 238

                         250       260       270
                  ....*....|....*....|....*....|....*.
gi 99030225   231 sWTKMPTLNTTLMLTLLSLAGLPPLTGFLPKWLIIQ 266
Cdd:pfam00361 239 -AKTMPILALVFLVAMLSLAGLPPTAGFLGKFLILA 273
NuoN COG1007
NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH: ...
 12-268 1.21e-21

NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 2 (chain N) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440631 [Multi-domain]  Cd Length: 473  Bit Score: 93.64  E-value: 1.21e-21
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 99030225  12 LLGTTITITSNHWMMAWTGLEINTLA--IIPHISKsHHPRSIEATTKYFLVQATASALMLF-SSMINAqLTGQWDITQL- 87
Cdd:COG1007 112 TLGMMLMASANDLLTLFLGLELLSLSlyVLVAFRR-DDRRSSEAALKYFLLGALSSGFLLYgISLLYG-ATGSLNLAGIa 189

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 99030225  88 -------TYPP----SCLLLTTAIAIKLGLAPFHFWFPDVLQGSPlttalllstlmklPPTT-----------------I 139
Cdd:COG1007 190 aalaaggANSPllllGLVLVLAGLAFKLSAVPFHMWTPDVYEGAP-------------TPVTaflatapkiaafaallrL 256

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 99030225 140 LLLTSHSLNP---TLLTTMSITSIA*GGWMGLNQTQTRKILAFSSISHLGWMTI-ITTYNPK-LTLLTFY--TYTLMTTS 212
Cdd:COG1007 257 LVEAFPGLAAdwqLLLAVLAVLSMTVGNLAALAQTNVKRMLAYSSIAHAGYLLLgLAAGTPLgVSAALFYllAYLFMNLG 336

                       250       260       270       280       290       300
                ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 99030225 213 IFLTMNTTNTLKLPTLMTS-----WTKMPTLNTTLMLTLLSLAGLPPLTGFLPKWLIIQEL 268
Cdd:COG1007 337 AFAVILLLSRKGGEAEEIEdlaglARRSPLLALAMTIFLLSLAGIPPTAGFFGKFYVFSAA 397
ND2 MTH00199
NADH dehydrogenase subunit 2; Provisional
 11-265 2.50e-20

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177245 [Multi-domain]  Cd Length: 460  Bit Score: 89.69  E-value: 2.50e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 99030225   11 LLLGTTITITSNHWMMAWTGLEINTLAI-IPHISKSHHPRSIEATTKYFLVQATASALMLFSSMINAQLTGQWDITQLTY 89
Cdd:MTH00199 106 VALGSLLLVSSINWLSIYLAIELQTLTLfILVALKRDSAYSTEAGLKYFVLGAVSSGLFLFGCALLYGLTGETSIQGINS 185

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 99030225   90 PPSC----LLLTTAIAIKLGLAPFHFWFPDVLQGSPLTTALLLSTLMKLPPTTILLLTSHSLNPTLLTtmSITSIA*GGW 165
Cdd:MTH00199 186 ILTGdvgkILITISLLFKLSAAPFHMWAPDVYEGAPTITTALLATVPKIGVFSILVQIGPVTNVVLIC--AVLSIIYGAI 263

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 99030225  166 MGLNQTQTRKILAFSSISHLGW----MTIITTYNPKLTLLTFYTYTLMTT---SIFLTMNTTNTLKLPTLMTSwTKMPTL 238
Cdd:MTH00199 264 GALNQTKIKRLLAYSGIGHMGFilfgVAIGSFESIQASLIYMIIYVIMSIcsfSIILSLKLTKGLIVEVSGLS-RKNPVI 342

                        250       260
                 ....*....|....*....|....*..
gi 99030225  239 NTTLMLTLLSLAGLPPLTGFLPKWLII 265
Cdd:MTH00199 343 ALTLALTFLSIAGIPPLAGFLSKWLIL 369
PRK05777 PRK05777
NADH-quinone oxidoreductase subunit NuoN;
12-266 1.69e-18

NADH-quinone oxidoreductase subunit NuoN;


Pssm-ID: 235603 [Multi-domain]  Cd Length: 476  Bit Score: 84.49  E-value: 1.69e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 99030225   12 LLGTTITITSNHWMMAWTGLEINTLA--IIPHISKsHHPRSIEATTKYFLVQATASALMLF-SSMINAqLTGQWDITQL- 87
Cdd:PRK05777 113 LLGMMVMVSANDLLTLFLGLELLSLPlyALAALRR-DRRRSLEAAIKYFVLGALASGFLLYgMSLLYG-ATGSLSFAGIa 190

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 99030225   88 -------TYPP----SCLLLTTAIAIKLGLAPFHFWFPDVLQGSPLTTALLLSTLMKL----PPTTILLLTSHSLNPT-- 150
Cdd:PRK05777 191 kaladgsGNSLlllfGLVFLLVGLAFKLSAVPFHMWTPDVYEGAPTPVTAFLATAPKIaafaVLLRLLVVAFGGLSEDwq 270

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 99030225  151 -LLTTMSITSIA*GGWMGLNQTQTRKILAFSSISHLGWMTI---ITTYNPKLTLLtFY--TYTLMTTSIF--LTMNTTNT 222
Cdd:PRK05777 271 qVLAIIAIASMLVGNLAALSQTNIKRLLAYSSIAHAGYLLVglaAGTAEGYSAVL-FYllAYLFMTLGAFgvISLLRRKG 349

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*...
gi 99030225  223 LKLPTLmTSWT----KMPTLNTTLMLTLLSLAGLPPLTGFLPKWLIIQ 266
Cdd:PRK05777 350 GEAESI-SDFAglskRSPLLAAVMTIFMLSLAGIPPTAGFWGKFYVFE 396
ND2 MTH00198
NADH dehydrogenase subunit 2; Provisional
 13-265 2.35e-16

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214454 [Multi-domain]  Cd Length: 607  Bit Score: 78.36  E-value: 2.35e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 99030225   13 LGTTITITSNHWMMAWTGLEINTLAIIPHISKSHHPRSI---------EATTKYFLVQATASALMLFSSMINAQLTGQ-- 81
Cdd:MTH00198 199 LGGLLLIESANWLTIYLALEFQTLALFILAGEGSQPGSHfpspgntppESGLKYWILGAMSSGFYLFGCALYFGFTGNeg 278

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 99030225   82 ------------WDITQLTYPPSCLLLTTAIAIKLGLAPFHFWFPDVLQGSPLTTALLLSTLMKLppTTILLLTSHSLNP 149
Cdd:MTH00198 279 mlgtilsatletTNIELRQGSLGYLFITVAILFKLAAAPFHMWTPDVYEGAPTPTTALIAIIPKF--TVYILLTSLVITS 356

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 99030225  150 TLLTTMSITSIA*GGWMGLNQTQTRKILAFSSISHLGWMTIITTYNPKLTLLTFYTYTLM-TTSIFLTMNTTNTL----- 223
Cdd:MTH00198 357 KLLLSVAIISLVVGAFGALNQTRIKRLLAYSGIGHIGFILIGVSAGTYESLQASWTYAVTyLVSALASFTVICTLeefgt 436

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 99030225  224 -------------------KLPTLMTSWTKMPTLNTTLMLTLLSLAGLPPLTGFLPKWLII 265
Cdd:MTH00198 437 rtptsrqrdgsfgnynlvrRLVDLTILSRGQPYIAFSLAIVFLSLAGIPPLLGFLGKWFIL 497
NDH_I_N TIGR01770
proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th ...
 12-273 6.93e-16

proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th (based on E. coli) structural gene, N, of bacterial and chloroplast energy-transducing NADH (or NADPH) dehydrogenases. This model does not describe any subunit of the mitochondrial complex I (for which the subunit composition is very different), nor NADH dehydrogenases that are not coupled to ion transport. The Enzyme Commission designation 1.6.5.3, for NADH dehydrogenase (ubiquinone), is applied broadly, perhaps unfortunately, even if the quinone is menaquinone (Thermus, Mycobacterium) or plastoquinone (chloroplast). For chloroplast members, the name NADH-plastoquinone oxidoreductase is used for the complex and this protein is designated as subunit 2 or B. This model also includes a subunit of a related complex in the archaeal methanogen, Methanosarcina mazei, in which F420H2 replaces NADH and 2-hydroxyphenazine replaces the quinone. [Energy metabolism, Electron transport]


Pssm-ID: 273795 [Multi-domain]  Cd Length: 468  Bit Score: 76.91  E-value: 6.93e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 99030225    12 LLGTTITITSNHWMMAWTGLEINTLAI-IPHISKSHHPRSIEATTKYFLVQATASALMLFSSMINAQLTGQWDITQLTYP 90
Cdd:TIGR01770 112 LLGIFLLVSSNDLLSIYLGLELQSLCFyVLAGLKRKSRFSTEAGLKYFILGAFSSGLLLFGISLIYGFTGSLNFEDLLLF 191

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 99030225    91 PSC------------LLLTTAIAIKLGLAPFHFWFPDVLQGSPLTTALLLSTLMKLPPTTILL-------LTSHSLNPTL 151
Cdd:TIGR01770 192 LSNgmlnisllllgiVLILVGLLFKLSAVPFHMWVPDVYEGAPTPVTAFFSIVPKIAIFAVFLrlflyilFGFSEAWQIF 271

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 99030225   152 LTTMSITSIA*GGWMGLNQTQTRKILAFSSISHLGW----MTIITTYNPKLTLLTFYTYTLMTTSIFLTMNTTNTLKLP- 226
Cdd:TIGR01770 272 LAIIAFLSMLIGNFGALAQKKVKRLLAYSSISHVGYiligLLAGTLEGIKAVLFYIFIYALMSLGAFGVLSLLRSYKDEw 351

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|..
gi 99030225   227 ----TLMTSWTKM-PTLNTTLMLTLLSLAGLPPLTGFLPKWLIIQELTKQEM 273
Cdd:TIGR01770 352 ieyiSDFAGLFKTnPILAILILIFMFSLAGIPPLAGFFGKFYVFFALLKSGL 403
HyfB COG0651
Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit [Energy ...
 11-266 4.28e-15

Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit [Energy production and conversion, Inorganic ion transport and metabolism];


Pssm-ID: 440416 [Multi-domain]  Cd Length: 430  Bit Score: 74.41  E-value: 4.28e-15
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 99030225  11 LLLGTTITITSNHWMMAWTGLEINTLAIIPHISKSHHPRSIEATTKYFLVQATASALMLFSSMINAQLTGQWDITQL--- 87
Cdd:COG0651 116 LLAGMNGAFLTGDLFNLFVFFEVMLLASYGLVALGGTKEALRAGLKYLILNLVGSALFLLGVGLLYGATGTLNMADLaar 195

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 99030225  88 --TYPPS-----CLLLTTAIAIKLGLAPFHFWFPDVLQGSPLTTALLLSTLM-KLPP----TTILLLTSHSLNP---TLL 152
Cdd:COG0651 196 laELDPGlllaaFALLLVGFGIKAALFPLHFWLPDAYPAAPSPVSALLSGLLtKVGVyailRVLTLLFGADPALflgTLL 275

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 99030225 153 TTMSITSIA*GGWMGLNQTQTRKILAFSSISHLGWMTI-ITTYNPKLTLLTFY---TYTLMTTSIFLT----MNTTNTLK 224
Cdd:COG0651 276 LVLGLLTMLVGALGALAQRDLKRLLAYSSVSQIGYILLgLGLGTPLGLAGALFhllNHALAKALLFLAagaiERATGTRD 355

                       250       260       270       280
                ....*....|....*....|....*....|....*....|..
gi 99030225 225 LPTLMTSWTKMPTLNTTLMLTLLSLAGLPPLTGFLPKWLIIQ 266
Cdd:COG0651 356 LDKLGGLGKRMPLTAAAFLIGALALAGLPPLSGFVSKWLLLQ 397
ndhB CHL00049
NADH dehydrogenase subunit 2
 49-261 5.86e-13

NADH dehydrogenase subunit 2


Pssm-ID: 176990 [Multi-domain]  Cd Length: 494  Bit Score: 68.11  E-value: 5.86e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 99030225   49 RSIEATTKYFLVQATASALMLF---------------SSMINAQLTgqwdiTQLTYPPSCLL----LTTAIAIKLGLAPF 109
Cdd:CHL00049 159 RSNEATMKYLLMGGASSSILVYgfswlyglsggeielQEIVNGLIN-----TQMYNSPGISIalifITVGIGFKLSLAPF 233

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 99030225  110 HFWFPDVLQGSPLTTALLLSTLMKLP----PTTILLLTSHSLNP---TLLTTMSITSIA*GGWMGLNQTQTRKILAFSSI 182
Cdd:CHL00049 234 HQWTPDVYEGSPTPVVAFLSVTSKVAasalATRIFDIPFYFSSNewhLLLEILAILSMILGNLIAITQTSMKRMLAYSSI 313

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 99030225  183 SHLGWMTI-ITTYNPKLTLLTFYTYTLMttSIFLTMNTTNTLKLPTLMT----------SWTKMPTLNTTLMLTLLSLAG 251
Cdd:CHL00049 314 GQIGYVIIgIIVGDSNDGYASMITYMLF--YIFMNLGTFACIVLFGLRTgtdnirdyagLYTKDPFLALSLALCLLSLGG 391

                        250
                 ....*....|
gi 99030225  252 LPPLTGFLPK 261
Cdd:CHL00049 392 IPPLAGFFGK 401
NuoM COG1008
NADH:ubiquinone oxidoreductase subunit 4 (chain M) [Energy production and conversion]; NADH: ...
 47-190 1.97e-11

NADH:ubiquinone oxidoreductase subunit 4 (chain M) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 4 (chain M) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440632 [Multi-domain]  Cd Length: 488  Bit Score: 63.56  E-value: 1.97e-11
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 99030225  47 HPRSIEATTKYFLVQATASALMLFSSMINAQLTGQW-----DITQLTYPPS-----CLLLTTAIAIKLGLAPFHFWFPDV 116
Cdd:COG1008 156 GERRIYAAIKFFLYTLAGSLLMLVAILALYFLAGALtfdiaELAAAPLPLTaqlllFLAFFIAFAVKVPMFPFHTWLPDA 235

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 99030225 117 LQGSPlttalllstlmklPPTTILL---------------------LTSHSLNPTLLTtMSITSIA*GGWMGLNQTQTRK 175
Cdd:COG1008 236 HVEAP-------------TAGSVLLagvllkmggygllrfalplfpEASAYFAPLLAA-LGVIGIIYGALVALAQTDLKR 301

                       170
                ....*....|....*
gi 99030225 176 ILAFSSISHLGWMTI 190
Cdd:COG1008 302 LIAYSSVSHMGFVLL 316
PRK08668 PRK08668
NADH dehydrogenase subunit M; Validated
 32-273 4.52e-09

NADH dehydrogenase subunit M; Validated


Pssm-ID: 236332 [Multi-domain]  Cd Length: 610  Bit Score: 56.54  E-value: 4.52e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 99030225   32 EINTLA---IIPHISKshhpRSIEATTKYFLVQATASALMLFSSMINAQLTGQWDITQ----LTYPPS-------CLLLT 97
Cdd:PRK08668 128 EIMTFSsfmMVPMGKK----ESRKASLKYFVLSAIGAYAMLYAIFLIYAKTGTFDFADisqgLINDTStgfalivFLFLL 203

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 99030225   98 TAIAIKLGLAPFHFWFPDVLQGSPLTTALL------------LSTLMKLPPTTILLLT-----SHSLNPTLLTTMSITSI 160
Cdd:PRK08668 204 AFGVAKAGIFPLHVWAPDAYSEAPQSFSAVlsgqlsklgaygFLLVLYVLPGTKLFSEfgtyrGVPLFNYILAWLGNISI 283

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 99030225  161 A*GGWMGLNQTQTRKILAFSSISHLGWMTI----ITTYNPKLTLLTFYTYTLMTTSIFLTMNT----TNTLKLPTLMTSW 232
Cdd:PRK08668 284 IVGTLMAILQEDIKKLIAYSSVANGGYILVglglGTSLGFAGGLFHVFNHALFKGLFFLIFAAviyrTGTTKISEMGGLI 363

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|.
gi 99030225  233 TKMPTLNTTLMLTLLSLAGLPPLTGFLPKWLIIQELTKQEM 273
Cdd:PRK08668 364 EKMPFTFAMYLVAIISLAGIPPMSGFASKWLIFEALISKGM 404
PRK08376 PRK08376
putative monovalent cation/H+ antiporter subunit D; Reviewed
 31-264 9.68e-09

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 236252 [Multi-domain]  Cd Length: 521  Bit Score: 55.49  E-value: 9.68e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 99030225   31 LEINTLAIIPHIS-KSHHPRSIEATTKYFLVQATASALMLFSSminAQLTGQWDITQLTY-------PPSCL------LL 96
Cdd:PRK08376 150 LEIMSIASYALVAfRNDTWEAIEAGIKYMFVGSLASSMVLLGI---ALLYGQYGTLNMAYlavkmseNPTVVakialaLF 226

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 99030225   97 TTAIAIKLGLAPFHFWFPDVLQGSPLTTALLLSTLMKLPPTTI----LLLTSHSLNPT----LLTTMSITSIA*GGWMGL 168
Cdd:PRK08376 227 IAGLAMKSGAVPVHMWLPDAYPAAPSSISAMLLVIKQAGLYALarvlFSIYGPAINLAtvgwVIIILGCLTMFVGVAMAV 306

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 99030225  169 NQTQTRKILAFSSISHLGWMTI-----ITTYNPklTLLTFYTYTLMTTSIFLTMN-----------------TTNTLKLP 226
Cdd:PRK08376 307 VQKDVKRLLAYHSVSQIGYMLLglgvgLAALGD--PAMASYGEIALAGGIYHIVNhalykallfltagaviyETGTRNLN 384

                        250       260       270
                 ....*....|....*....|....*....|....*...
gi 99030225  227 TLMTSWTKMPTLNTTLMLTLLSLAGLPPLTGFLPKWLI 264
Cdd:PRK08376 385 ELGGLARTMPKTTIAFLIGAAAIVGLPPFNGFASKWLI 422
NDH_I_M TIGR01972
proton-translocating NADH-quinone oxidoreductase, chain M; This model describes the 13th ...
 48-266 3.05e-08

proton-translocating NADH-quinone oxidoreductase, chain M; This model describes the 13th (based on E. coli) structural gene, M, of bacterial NADH dehydrogenase I, as well as chain 4 of the corresponding mitochondrial complex I and of the chloroplast NAD(P)H dehydrogenase complex. [Energy metabolism, Electron transport]


Pssm-ID: 273903 [Multi-domain]  Cd Length: 481  Bit Score: 54.18  E-value: 3.05e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 99030225    48 PRSIEATTKYFLVQATASALMLfSSMINAQLTGQW-----DITQLTYPPSC-----LLLTTAIAIKLGLAPFHFWFPDV- 116
Cdd:TIGR01972 152 PNRIYAAMKFFLYTLAGSLLML-LAILGLYFLGGGtfdllELLNLPLPFGVqtwlfLAFFIAFAVKVPLFPLHTWLPDAh 230

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 99030225   117 LQGSPLTTALLLSTLMKLPPTTILLL-------TSHSLNPtLLTTMSITSIA*GGWMGLNQTQTRKILAFSSISHLGWMT 189
Cdd:TIGR01972 231 VEAPTAGSVILAGVLLKMGTYGFLRFnlplfpdASLYFAP-VLAALGVIAIIYGALIALAQTDIKRLIAYSSISHMGFVL 309

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 99030225   190 I-ITTYNPKLT---LLTFYTYTLMTTSIFLTMNT----TNTLKLPTLMTSWTKMPTLNTTLMLTLLSLAGLPPLTGFLPK 261
Cdd:TIGR01972 310 LgIFSFNELGIsgaVFQMISHGLITAALFLLVGVlyerAHTRDIAKYGGLANKMPVLAAFFMLFAMASLGLPGTSGFVGE 389


                  ....*
gi 99030225   262 WLIIQ 266
Cdd:TIGR01972 390 FLILL 394
PRK02504 PRK02504
NAD(P)H-quinone oxidoreductase subunit N;
48-190 4.39e-08

NAD(P)H-quinone oxidoreductase subunit N;


Pssm-ID: 235044 [Multi-domain]  Cd Length: 513  Bit Score: 53.52  E-value: 4.39e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 99030225   48 PRSIEATTKYFLVQATASALMLF-SSMINAQLTGQWDIT----QLTYPPSCLLLTT------AIAIKLGLAPFHFWFPDV 116
Cdd:PRK02504 157 PRSNEAALKYLLIGAASSAIFLYgSSLLYGLSGGSTQLSaialALITSPSLGLALAlvfviaGIAFKISAVPFHQWTPDV 236

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 99030225  117 LQGSPLTTALLLSTLMKLPPTTI---LLLTSHSLNPT----LLTTMSITSIA*GGWMGLNQTQTRKILAFSSISHLGWMT 189
Cdd:PRK02504 237 YEGSPTPVVAFLSVGSKAAGFALairLLVTAFPSFDEqwklLFTALAILSMVLGNVVALAQTSMKRMLAYSSIGQAGFVM 316


                 .
gi 99030225  190 I 190
Cdd:PRK02504 317 I 317
PRK05846 PRK05846
NADH:ubiquinone oxidoreductase subunit M; Reviewed
 48-190 6.26e-07

NADH:ubiquinone oxidoreductase subunit M; Reviewed


Pssm-ID: 235622 [Multi-domain]  Cd Length: 497  Bit Score: 50.20  E-value: 6.26e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 99030225   48 PRSIEATTKYFLVQATASALMLFSSM----INAQLTGQWDITQLTYPPSCLLLTT--------AIAIKLGLAPFHFWFPD 115
Cdd:PRK05846 157 KNRIYAATKFFLYTLLGSLLMLVAIIylvvVYYNATGTFDIADLLNLPLPPGVQYwlflaffiAFAVKMPMFPLHTWLPD 236

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 99030225  116 VLQGSPlttalllstlmklPPTTILL---------------------LTSHSLNPtLLTTMSITSIA*GGWMGLNQTQTR 174
Cdd:PRK05846 237 AHVQAP-------------TAGSVLLagillkmgaygllrfslplfpDASHEFAP-IIITLGVIAIIYGALVALAQTDIK 302

                        170
                 ....*....|....*.
gi 99030225  175 KILAFSSISHLGWMTI 190
Cdd:PRK05846 303 KLIAYSSISHMGFVTL 318
NuoL COG1009
Membrane H+-translocase/NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ ...
 46-268 6.40e-07

Membrane H+-translocase/NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit [Energy production and conversion]; Membrane H+-translocase/NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440633 [Multi-domain]  Cd Length: 608  Bit Score: 50.15  E-value: 6.40e-07
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 99030225  46 HHPRSIEATTKYFLVQATASALMLFSSMINAQLTGQWDITQL-----------TYPPSCLLLTTAIAIKLGLAPFHFWFP 114
Cdd:COG1009 156 EKPSARRAARKAFLVTRVGDLGLLLGILLLGAIAGTLNFSELlaaaptilsspLLTLILLLLLLGAFGKSAQFPLHFWLP 235

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 99030225 115 DVLQGsplttalllstlmklpPTTI---------------LLLTSH---SLNPTLLTTMSITSIA---*GGWMGLNQTQT 173
Cdd:COG1009 236 DAMEG----------------PTPVsallhaatmvkagvyLLARLSplfALSPVWLTVVAIIGAItalFAALIALAQTDI 299

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 99030225 174 RKILAFSSISHLGWMTI---ITTYNPKLTLLTFYTYT-----LMTTSIFLTMNTTNTLKLPTLmtsWTKMPTLNTTLMLT 245
Cdd:COG1009 300 KRVLAYSTVSQLGYMFLalgVGAYVAALFHLLTHAFFkallfLGAGSVIHATGTRDIRKMGGL---RKKMPITAITFLIG 376

                       250       260
                ....*....|....*....|...
gi 99030225 246 LLSLAGLPPLTGFLPKWLIIQEL 268
Cdd:COG1009 377 ALSLAGIPPFAGFFSKEAILEAA 399
PRK08375 PRK08375
putative monovalent cation/H+ antiporter subunit D; Reviewed
 31-268 7.94e-07

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 236251 [Multi-domain]  Cd Length: 487  Bit Score: 49.88  E-value: 7.94e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 99030225   31 LEINTLAIIPHISKSHHPRSIEATTKYFLVQATASALMLFSSMINAQLTGQWDITQLT--YPPSCLLLT------TAIAI 102
Cdd:PRK08375 135 LEIMSLSSYALVAMGGDRRALAAARKYLIVGLIGSTFLLIGVGLLYGVTGTLNMADLAgaLAENPTVVTafgfvlLALAL 214

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 99030225  103 KLGLAPFHFWFPDVLQG-SPLTTALLLSTLMKLPPTTILLLTSH----------SLNPTLLTTMSItSIA*GGWMGLNQT 171
Cdd:PRK08375 215 KAAVFPLHTWLPRAYPAaPPVVTALLSGLVTKVAVYALIRIYFTvfggdfrfalGLGWLLAVLALL-SMLVGSLAALGQD 293

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 99030225  172 QTRKILAFSSISHLGWMTI-ITTYNPK-LTLLTFYT--YTLMTTSIFLT----MNTTNTLKLPTLMTSWTKMPTLNTTLM 243
Cdd:PRK08375 294 DVKRVLAYSTVSQMGYILLgLALLTPLaLAAGLLHLlhHALMKGALFLAagaiEVTYGTRRLSELSGLGRRMPLTAAAFA 373

                        250       260
                 ....*....|....*....|....*
gi 99030225  244 LTLLSLAGLPPLTGFLPKWLIIQEL 268
Cdd:PRK08375 374 VASLSLIGVPPTSGFVSKWYLVVGA 398
PRK12649 PRK12649
putative monovalent cation/H+ antiporter subunit A; Reviewed
 46-261 1.90e-06

putative monovalent cation/H+ antiporter subunit A; Reviewed


Pssm-ID: 183649 [Multi-domain]  Cd Length: 789  Bit Score: 48.67  E-value: 1.90e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 99030225   46 HHPRSIEATTKYFLVQATASALMLFSSMINAQLTGQWDITQLTYPPSC--------LLLTTAIAIKLGLA------PFHF 111
Cdd:PRK12649 156 HRPESVYGATKSLLITAGGGLFMFAGFLLLHVITGTYDIATILQDSELienikghpLFLITLILIFIGAAaksaqgPFYI 235

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 99030225  112 WFPDVLQGSPLTTALLLSTLMKLPPTTILLLTSHSLNPT-----LLTTMSITSIA*GGWMGLNQTQTRKILAFSSISHLG 186
Cdd:PRK12649 236 WLPNAMEAPTPVSAFLHSATMVKAGVYLVARIHPIFSGTeawfiLVSGTGMITMVLAGFLAFRQTDIKAILAYSTISQLA 315

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 99030225  187 WMTII---TTYNPKLTLLTFYTYTLMTTSIF---------LTMNTTNTLKLPTLMTSWTKMPTLNTTLMLTLLSLAGLPP 254
Cdd:PRK12649 316 YLMTMygyTTYHEPGLGVAAATFHLLNHATFkaclflvagIVAHEAATRDIRKLGGLRKEMPITFIVASIAALAMAGIPP 395


                 ....*..
gi 99030225  255 LTGFLPK 261
Cdd:PRK12649 396 LNGFLSK 402
PRK12644 PRK12644
putative monovalent cation/H+ antiporter subunit A; Reviewed
 59-261 2.24e-06

putative monovalent cation/H+ antiporter subunit A; Reviewed


Pssm-ID: 237154 [Multi-domain]  Cd Length: 965  Bit Score: 48.77  E-value: 2.24e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 99030225   59 LVQATASAL-MLFSSMINAQLTGQWDITQL-TYPPSCLLLTTAIAI-------KLGLAPFHFWFPDVLQG-SPLTTALLL 128
Cdd:PRK12644 163 LLVTTAGGLaMLVGIIILGQAAGTYRLSELlADPPTGPAVSVAVVLilvgalsKSAIVPFHFWLPGAMAApTPVSAYLHA 242

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 99030225  129 STLMKLPPTTILLLT-----SHSLNPTLLTTMSITSIa*GGWMGLNQTQTRKILAFSSISHLGWMTIITTYNPK------ 197
Cdd:PRK12644 243 AAMVKAGIYLVARLApgfadVPVWRPTVLVLGLATML-LGGWRALRQHDLKLILAYGTVSQLGFLTVLVGIGTRdaalag 321

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 99030225  198 LTLLTfyTYTLMTTSIFLTM----NTTNTLKLPTLMTSWTKMPTLNTTLMLTLLSLAGLPPLTGFLPK 261
Cdd:PRK12644 322 LAMLL--AHALFKAALFLVVgiidHSTGTRDIRKLSGLGRRQPVLAVVAALAAASMAGLPPLLGFVAK 387
PRK12650 PRK12650
DUF4040 family protein;
96-261 1.57e-05

DUF4040 family protein;


Pssm-ID: 237158 [Multi-domain]  Cd Length: 962  Bit Score: 46.19  E-value: 1.57e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 99030225   96 LTTAIAIKLGLA--------PFHFWFPDVLQG-SPLTTALLLSTLMKlppTTILLLTSHSL----NPT---LLTTMSITS 159
Cdd:PRK12650 206 LTTVVAVLIAVAaftksaqfPFHFWLPEAMAAiTPVSAFLHAAAVVK---AGIYLLLRFSPvfhdVAVwnwLLIIVGMIT 282

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 99030225  160 IA*GGWMGLNQTQTRKILAFSSISHLGWM-TIITTYNP-KLTLLTFYT--YTLMTTSIFLTM----NTTNTLKLPTLMTS 231
Cdd:PRK12650 283 ALMGAVFAVQKTDLKKLTAYSTVSQLGWIvATIGVGTPfALTAAVVHTlaHALFKSSLFMLIgvvdHQAGTRDIRRLGSL 362

                        170       180       190
                 ....*....|....*....|....*....|
gi 99030225  232 WTKMPTLNTTLMLTLLSLAGLPPLTGFLPK 261
Cdd:PRK12650 363 WRRMPFTFVSVTIAALSMAAVPPLFGFVSK 392
PRK08676 PRK08676
hydrogenase membrane subunit; Validated
 11-190 2.36e-05

hydrogenase membrane subunit; Validated


Pssm-ID: 181537 [Multi-domain]  Cd Length: 485  Bit Score: 45.13  E-value: 2.36e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 99030225   11 LLLGTTITITSNHWMMAWTGLEINTLAIIPHISKSHHPRSIEATTKYFLVQATA------SALMLFSSMINAQLTGQWDI 84
Cdd:PRK08676 111 LLSVITFAFFSDNLALFWIFAELTTVFSAMLIAILSARENIDAALKYIFIASTAmifafiGLIFLFSLTRQALGTGTLNW 190

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 99030225   85 TQLT-----YPPSCLLLT-----TAIAIKLGLAPFHFWFPDVLQGSPLTTALLLSTLM-KLPPTTILLLTS-------HS 146
Cdd:PRK08676 191 TELAahaslLSPSVLGASflfifIGFLAKSGLVPFHTWLPAAYAKAPSVVSALLSGTVlNIGIYGILRLSAllrqsgaAE 270

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....
gi 99030225  147 LNPTLLTTMSITSIA*GGWMGLNQTQTRKILAFSSISHLGWMTI 190
Cdd:PRK08676 271 QFSNVLIGLGIFSIAVAAFSMLSQRNLKKLIAFSSIEHMGLMLL 314
PRK12667 PRK12667
putative monovalent cation/H+ antiporter subunit D; Reviewed
 46-268 7.01e-05

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 237167 [Multi-domain]  Cd Length: 520  Bit Score: 43.81  E-value: 7.01e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 99030225   46 HHPRSIEATTKYFLVQATASALMLFS-----------SMINAQLTGQWDITQLTYPPS----------CLLLTTAIAIKL 104
Cdd:PRK12667 158 DRGDAVEAAIKYALIGAVGTTLYFLAlaflyatfgtlNMADLSAKIRGLSFPLTGGLAgnpplalgvaLALALWAFTIKA 237

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 99030225  105 GLAPFHFWFPDVLQGSPLTTALLLSTLMK--------------LPPTTILLLTSHSLNPTLLTTMSITSIA*GGWMGLNQ 170
Cdd:PRK12667 238 AIFPNHFWLPDAHPAAPSPVSAMLSGLVVnvgayaiirflytiFGISPSLIDFRAALSPILIILGAVSAII-GALMMVVQ 316

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 99030225  171 TQTRKILAFSSISHLGWMTIITTYNPKLTLLTFYTYTL----------MTTSIFLtmNTTNTLKLPTLMTSWTKMPTLNT 240
Cdd:PRK12667 317 KDVKRLLAYSTISHMGYIFMGIGIGTQLGLAAALFHIInhaiaksllfLASGVFI--HAAGTRDIDELAGLGRKMPIASF 394

                        250       260
                 ....*....|....*....|....*...
gi 99030225  241 TLMLTLLSLAGLPPLTGFLPKWLIIQEL 268
Cdd:PRK12667 395 AFLIGALSLVGIPPLNGFFSKLLLFNAL 422
PRK12662 PRK12662
putative monovalent cation/H+ antiporter subunit D; Reviewed
 150-265 2.17e-04

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 183662 [Multi-domain]  Cd Length: 492  Bit Score: 42.41  E-value: 2.17e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 99030225  150 TLLTTMSITSIA*GGWMGLNQTQTRKILAFSSISHLGWMTIITTYNPKLTLLTFYTY----TLMTTSIFLTMNTT----N 221
Cdd:PRK12662 280 NVFMILAALAIVFGSVLAILSKDIKRIFAYSSISHIGYIILAVSLNTYYGLAAAVAYivnhSIVKSALFMVSGSIsyhfG 359

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....
gi 99030225  222 TLKLPTLMTSWTKMPTLNTTLMLTLLSLAGLPPLTGFLPKWLII 265
Cdd:PRK12662 360 TTKLEDCLNLWKSMPKITLAFVLLSLSLIGMPPTSGFVAKWYIL 403
PRK06458 PRK06458
hydrogenase 4 subunit F; Validated
 18-190 3.54e-04

hydrogenase 4 subunit F; Validated


Pssm-ID: 235805 [Multi-domain]  Cd Length: 490  Bit Score: 41.45  E-value: 3.54e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 99030225   18 TITSNHWMMAWTGLEINTLAIIPHISKSHHPRSIEATTKYFLVQATASALMLFSS----------MINAQLTGQWdiTQL 87
Cdd:PRK06458 124 ALTSNNLGLMWVAIEATTLSSALLVGIYRTRASLEAAWKYIIICSVGVAFALFGTilvyanaatvMGDGEMAILW--TEL 201

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 99030225   88 TYPPSCL---LLTTAIAI-------KLGLAPFHFWFPDVLQGSPLttalllstlmklpPTTILL---------------- 141
Cdd:PRK06458 202 LKHASLLdptLMKLAFVFlligfgtKVGLFPMHAWLPDAHSEAPS-------------PVSALLsgvllnvalyavlryy 268

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....
gi 99030225  142 -LTSHSLNP----TLLTTMSITSIA*GGWMGLNQTQTRKILAFSSISHLGWMTI 190
Cdd:PRK06458 269 iLIDAAIGSdfpgRLLLIFGLLSVLVAAFFLLRQRDIKRLFAYSSIEHMGLIAF 322
PRK12647 PRK12647
putative monovalent cation/H+ antiporter subunit A; Reviewed
 89-264 3.66e-04

putative monovalent cation/H+ antiporter subunit A; Reviewed


Pssm-ID: 237156 [Multi-domain]  Cd Length: 761  Bit Score: 41.83  E-value: 3.66e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 99030225   89 YPPSCLLLTTAIAIKLGLAPFHFWFPDVlqgsplttalllstlMKLP-PTTILLltsHS-------------LNP----- 149
Cdd:PRK12647 194 YLAILLLVLGGAFTKSAQFPFHFWLPNA---------------MEAPtPVSAYL---HSatmvkagiyllarLNPvlggt 255

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 99030225  150 ----TLLTTMSITSIA*GGWMGLNQTQTRKILAFSSISHLGWMTIITTYNPKLTLLTFYTY----TLMTTSIFLTMNT-- 219
Cdd:PRK12647 256 plwqTILPLFGGLTMLTGALLAVRQTDLKLILAYSTVSALGTLVMLLGLGSELAIKAAVLFlvahSLYKGALFMVAGIid 335

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*..
gi 99030225  220 --TNTLKLPTLMTSWTKMPTLNTTLMLTLLSLAGLPPLTGFLPKWLI 264
Cdd:PRK12647 336 heTGTRDITKLGGLRRAMPITAAAALLAALSMAGLPPLFGFLAKELI 382
PRK12561 PRK12561
NAD(P)H-quinone oxidoreductase subunit 4; Provisional
 53-272 4.35e-03

NAD(P)H-quinone oxidoreductase subunit 4; Provisional


Pssm-ID: 237137 [Multi-domain]  Cd Length: 504  Bit Score: 38.09  E-value: 4.35e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 99030225   53 ATTKYFLVQATASALMLFSSMINAQLTGQ--WDITQLT---YPPSCLLLT-----TAIAIKLGLAPFHFWFPDVL-QGSP 121
Cdd:PRK12561 138 AATKFILYTALASIFILVAGLALALSGDTftFDLAELGaksYPLALELLLyagflIAFGVKLPIFPLHTWLPDAHgEASA 217

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 99030225  122 LTTALLLSTLMKLPPTTI------LLLTSHSLNPTLLTTMSITSIA*GGWMGLNQTQTRKILAFSSISHLGWMTI----I 191
Cdd:PRK12561 218 PVSMILAGVLLKMGGYALirfnvqMLPDAHVYFAPALAILGVVNIIYGALNAFAQDNVKRRLAYSSVSHMGFVLLgiaaF 297

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 99030225  192 TTYNPKLTLLTFYTYTLMTTSIFL----TMNTTNTLKLPTLMTSWTKMPTLNTTLMLTLLSLAGLPPLTGFLPKWLIIQE 267
Cdd:PRK12561 298 TDLGISGAMLQMISHGLIAAALFFltgvTYERTHTLSIPNMGGLAKVMPKTFALFTASSMASLALPGMSGFVSELTVFLG 377


                 ....*
gi 99030225  268 LTKQE 272
Cdd:PRK12561 378 ITSSD 382
PRK07363 PRK07363
NADH-quinone oxidoreductase subunit M;
94-266 5.14e-03

NADH-quinone oxidoreductase subunit M;


Pssm-ID: 180945 [Multi-domain]  Cd Length: 501  Bit Score: 38.15  E-value: 5.14e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 99030225   94 LLLTTAI----AIKLGLAPFHFWFPDV-LQGSPLTTALLLSTLMKLPPTTILLL-------TSHSLNPTLLTTMSITSIa 161
Cdd:PRK07363 205 LILLTGLllgfGIKIPLVPLHTWLPDAyTEASPAVAILLGGVLAKLGTYGLLRFglqlfpqTWSLVAPGLAIIGTISVI- 283

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 99030225  162 *GGWMGLNQTQTRKILAFSSISHLGWMTIITTYNPKLTLL----TFYTYTLMTTSIF-------LTMNTTNTLKLPTLMT 230
Cdd:PRK07363 284 YGALSAIAQKDIKRMVAYSSIGHMGYILVAAAAGTQLSLLgavaQMISHGLILALLFhlvgiveRKVGTRDLDVLNGLMN 363

                        170       180       190
                 ....*....|....*....|....*....|....*.
gi 99030225  231 SWTKMPTLNTTLMLTLLSLAGLPPLTGFLPKWLIIQ 266
Cdd:PRK07363 364 PIRGLPLTSALLVLAGMASAGIPGLVGFVAEFIVFQ 399
PRK06277 PRK06277
energy conserving hydrogenase EhbF;
32-266 5.69e-03

energy conserving hydrogenase EhbF;


Pssm-ID: 235767 [Multi-domain]  Cd Length: 478  Bit Score: 37.70  E-value: 5.69e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 99030225   32 EINTLAIIPHISKSHHPRSIEATTKYFLVQATASALMLFSSMINAQLTGQWDITQLTY-----PPSCLLLTTAIAIKLGL 106
Cdd:PRK06277 130 EIAAIVQVGLVIASGTEEAYKAALKYMILGNVAGSILLLGIGFLLASTGTLNITDIHNallvnPTSPVIYGGLLLLIFGL 209

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 99030225  107 A------PFHFWFPDVLQGSPLTTALLLSTLMKLPPTTILL--------LTSHSLNPTLLTTMSITSIA*GGWMGLNQTQ 172
Cdd:PRK06277 210 LygsglpPFHTIKSDIYAKAKPFGSALLQTFSKFVLVALMLvifklfggLSYFPSAQGVLIALSVLAMVFGVVMALLQTD 289

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 99030225  173 TRKILAFSSISHLGW----MTIITTYNPKLTLLTFYTYTLMTTSIFL-------TMNTTNTLKLPTLMTSwtkMPTLNTT 241
Cdd:PRK06277 290 YKRLLAYHAISQGGYvaagLALGTPLGIVAGIFHAINHVIYKSALFLgagivsyRTKTSNLRKLGGLLPV---MPVVAFM 366

                        250       260
                 ....*....|....*....|....*
gi 99030225  242 LMLTLLSLAGLPPLTGFLPKWLIIQ 266
Cdd:PRK06277 367 VLCAKLAISGVPPFNGFQSKLMLAQ 391
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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