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Conserved domains on  [gi|985671309|gb|KXB02129|]
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hypothetical protein AKJ44_01365, partial [candidate division MSBL1 archaeon SCGC-AAA261F17]

Protein Classification

transposase( domain architecture ID 1750097)

IS5 family transposase binds to the end of a transposon and catalyzes the movement of the transposon to another part of the genome by a cut and paste mechanism or a replicative transposition mechanism

Gene Ontology:  GO:0003677|GO:0032196
PubMed:  20215432|30454069

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
transpos_IS5_2 super family cl41331
IS5 family transposase;
3-93 1.75e-29

IS5 family transposase;


The actual alignment was detected with superfamily member NF033579:

Pssm-ID: 468096 [Multi-domain]  Cd Length: 287  Bit Score: 105.83  E-value: 1.75e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985671309   3 INWSEYNEELVRRGE--FYLSPDFLDSWDEELErmneGKVGRPYEYPESFIQFAALWYEFFHLPYRQLEGALRKLGELL- 79
Cdd:NF033579   1 RNWSSYNVALAKRGSltIWLDPDALAQWYAPPK----GKRGRPQTYSDAAIQTLLLLKVLFGLPLRQTQGLLNSLFKLIg 76

                         90
                 ....*....|....
gi 985671309  80 PELKVADYTRLYRR 93
Cdd:NF033579  77 LDLAVPDYSTLCRR 90
 
Name Accession Description Interval E-value
transpos_IS5_2 NF033579
IS5 family transposase;
3-93 1.75e-29

IS5 family transposase;


Pssm-ID: 468096 [Multi-domain]  Cd Length: 287  Bit Score: 105.83  E-value: 1.75e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985671309   3 INWSEYNEELVRRGE--FYLSPDFLDSWDEELErmneGKVGRPYEYPESFIQFAALWYEFFHLPYRQLEGALRKLGELL- 79
Cdd:NF033579   1 RNWSSYNVALAKRGSltIWLDPDALAQWYAPPK----GKRGRPQTYSDAAIQTLLLLKVLFGLPLRQTQGLLNSLFKLIg 76

                         90
                 ....*....|....
gi 985671309  80 PELKVADYTRLYRR 93
Cdd:NF033579  77 LDLAVPDYSTLCRR 90
DDE_Tnp_1_5 pfam13737
Transposase DDE domain; Transposase proteins are necessary for efficient DNA transposition. ...
 13-93 1.52e-19

Transposase DDE domain; Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis.


Pssm-ID: 433444  Cd Length: 112  Bit Score: 76.22  E-value: 1.52e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985671309   13 VRRGE--FYLSPDFLDSWDEELERmneGKVGRPYEYPESFIQFAALWYEFFHLPYRQLEGALRKLGELLP-ELKVADYTR 89
Cdd:pfam13737   1 KNRGSltFWLDPDMIASWDEAPPP---GKRGRPQVYSDAAIQTCLTIKVLFGLPLRQTQGFVQSLLKLAGlDLPVPDYST 77


                  ....
gi 985671309   90 LYRR 93
Cdd:pfam13737  78 LSRR 81
 
Name Accession Description Interval E-value
transpos_IS5_2 NF033579
IS5 family transposase;
3-93 1.75e-29

IS5 family transposase;


Pssm-ID: 468096 [Multi-domain]  Cd Length: 287  Bit Score: 105.83  E-value: 1.75e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985671309   3 INWSEYNEELVRRGE--FYLSPDFLDSWDEELErmneGKVGRPYEYPESFIQFAALWYEFFHLPYRQLEGALRKLGELL- 79
Cdd:NF033579   1 RNWSSYNVALAKRGSltIWLDPDALAQWYAPPK----GKRGRPQTYSDAAIQTLLLLKVLFGLPLRQTQGLLNSLFKLIg 76

                         90
                 ....*....|....
gi 985671309  80 PELKVADYTRLYRR 93
Cdd:NF033579  77 LDLAVPDYSTLCRR 90
DDE_Tnp_1_5 pfam13737
Transposase DDE domain; Transposase proteins are necessary for efficient DNA transposition. ...
 13-93 1.52e-19

Transposase DDE domain; Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis.


Pssm-ID: 433444  Cd Length: 112  Bit Score: 76.22  E-value: 1.52e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985671309   13 VRRGE--FYLSPDFLDSWDEELERmneGKVGRPYEYPESFIQFAALWYEFFHLPYRQLEGALRKLGELLP-ELKVADYTR 89
Cdd:pfam13737   1 KNRGSltFWLDPDMIASWDEAPPP---GKRGRPQVYSDAAIQTCLTIKVLFGLPLRQTQGFVQSLLKLAGlDLPVPDYST 77


                  ....
gi 985671309   90 LYRR 93
Cdd:pfam13737  78 LSRR 81
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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