|
Name |
Accession |
Description |
Interval |
E-value |
| ClpA |
COG0542 |
ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein ... |
82-876 |
0e+00 |
|
ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 440308 [Multi-domain] Cd Length: 836 Bit Score: 1164.85 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 979895810 82 DAFSEQTLELLQRAAEKAHELRRSELDSEHLLYALADTD--VCAALLKELKLSPQDIRSYIDEHAHTGTADPDAPlDKLS 159
Cdd:COG0542 4 EKFTEKAQEALEAAQELARRLGHQEVEPEHLLLALLEQGegLAAKLLRKLGVDLDALREELEEALGRLPKVSGSS-GQPY 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 979895810 160 ISPRVKKAVQYAFQASRDLGHSYIGPEHLLIGLASVPDSVAGTLLKKYGVTPEALRQKVVKVVGKGAEDGRvDAPTGTPN 239
Cdd:COG0542 83 LSPRLKRVLELAELEARKLGDEYISTEHLLLALLREGEGVAARILKKLGITLEALREALEELRGGSRVTSQ-NPESKTPA 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 979895810 240 LDKFGRDLTAIARQGKLDPVLGRAQEIESTIEVLARRKKNNPVLIGEPGVGKTAIVEGLAQRIVNGDVPEVLRDKRLVEV 319
Cdd:COG0542 162 LDKYGRDLTELAREGKLDPVIGRDEEIRRVIQILSRRTKNNPVLIGEPGVGKTAIVEGLAQRIVNGDVPESLKDKRVLSL 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 979895810 320 NINSMVAGAKYRGEFEERAKQLIDEVTAKQDELILFIDELHTIVgagqgggeggLDIANVLKPALARGELSLIGATTLNE 399
Cdd:COG0542 242 DLGALVAGAKYRGEFEERLKAVLDEVKKSEGNIILFIDELHTLVgagg--aegaMDAANLLKPALARGELRCIGATTLDE 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 979895810 400 YQKYIEKDAALERRFQPVFVPEPSVEQTIVILRGLRDSLEAHHQVTFADDAFVAAAEFADRYITSRFLPDKAIDLIDQAA 479
Cdd:COG0542 320 YRKYIEKDAALERRFQPVLVEEPSVEDTISILRGLKERYEAHHGVRITDEALVAAVRLSDRYITDRFLPDKAIDLIDEAA 399
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 979895810 480 ARVRIGATSRPVDIQEGEAQIAQLKREQDYA---TSRKRFDEAKQFEEQINAKQKSVDEMMEAWQR-------------- 542
Cdd:COG0542 400 ARVRMEIDSKPEELDELERRLEQLEIEKEALkkeQDEASFERLAELRDELAELEEELEALKARWEAekelieeiqelkee 479
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 979895810 543 ---------------KTGSETL---------EVTVESVAEVVSRLTGIPVSELTQEERQKLLKMEEQLRERVVGQSDAVV 598
Cdd:COG0542 480 leqrygkipelekelAELEEELaelapllreEVTEEDIAEVVSRWTGIPVGKLLEGEREKLLNLEEELHERVIGQDEAVE 559
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 979895810 599 AVSDAVRLSRAGLGQTHRPIATFLFLGPTGVGKTELAKALAETVFGDEQAIIRIDMSEYMERHAVARLIGAPPGYVGYDE 678
Cdd:COG0542 560 AVADAIRRSRAGLKDPNRPIGSFLFLGPTGVGKTELAKALAEFLFGDEDALIRIDMSEYMEKHSVSRLIGAPPGYVGYEE 639
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 979895810 679 GGQLTERVRRRPYSVILLDEIEKAHPDVYNVLLQVFDDGRLTDGKGRVVDFSNTIIIATSNLGAAIIMDNLTQPEaarkT 758
Cdd:COG0542 640 GGQLTEAVRRRPYSVVLLDEIEKAHPDVFNILLQVLDDGRLTDGQGRTVDFRNTIIIMTSNIGSELILDLAEDEP----D 715
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 979895810 759 DKAIREELMQVLKGHFRPEFLNRIDEVIVFHALSKENIRSIVQIQLDRVIRTAAAQDITLVMGDSLVEHLTEAGYQPEFG 838
Cdd:COG0542 716 YEEMKEAVMEELKKHFRPEFLNRIDEIIVFHPLSKEELRKIVDLQLKRLRKRLAERGITLELTDAAKDFLAEKGYDPEYG 795
|
810 820 830
....*....|....*....|....*....|....*...
gi 979895810 839 ARELKRQIRQTIETRLAKEILADRLKSGDKCEVDYDKD 876
Cdd:COG0542 796 ARPLKRAIQRELEDPLAEEILAGEIKEGDTITVDVDDG 833
|
|
| chaperone_ClpB |
TIGR03346 |
ATP-dependent chaperone ClpB; Members of this protein family are the bacterial ATP-dependent ... |
84-876 |
0e+00 |
|
ATP-dependent chaperone ClpB; Members of this protein family are the bacterial ATP-dependent chaperone ClpB. This protein belongs to the AAA family, ATPases associated with various cellular activities (pfam00004). This molecular chaperone does not act as a protease, but rather serves to disaggregate misfolded and aggregated proteins. [Protein fate, Protein folding and stabilization]
Pssm-ID: 274529 [Multi-domain] Cd Length: 850 Bit Score: 954.02 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 979895810 84 FSEQTLELLQRAAEKAHELRRSELDSEHLLYALADTD--VCAALLKELKLSPQDIRSYIDEHAHTgTADPDAPLDKLSIS 161
Cdd:TIGR03346 1 LTEKFQEALQAAQSLALGRDHQQIEPEHLLKALLDQEggLARPLLQKAGVNVGALRQALEKELER-LPKVSGPGGQVYLS 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 979895810 162 PRVKKAVQYAFQASRDLGHSYIGPEHLLIGLASVPDSvAGTLLKKYGVTPEALRQKVVKVVG------KGAEDGRvDApt 235
Cdd:TIGR03346 80 PDLNRLLNLAEKLAQKRGDEFISSEHLLLALLDDKGT-LGKLLKEAGATADALEAAINAVRGgqkvtdANAEDQY-EA-- 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 979895810 236 gtpnLDKFGRDLTAIARQGKLDPVLGRAQEIESTIEVLARRKKNNPVLIGEPGVGKTAIVEGLAQRIVNGDVPEVLRDKR 315
Cdd:TIGR03346 156 ----LEKYARDLTERAREGKLDPVIGRDEEIRRTIQVLSRRTKNNPVLIGEPGVGKTAIVEGLAQRIVNGDVPEGLKNKR 231
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 979895810 316 LVEVNINSMVAGAKYRGEFEERAKQLIDEVTAKQDELILFIDELHTIVGAGQGGGEggLDIANVLKPALARGELSLIGAT 395
Cdd:TIGR03346 232 LLALDMGALIAGAKYRGEFEERLKAVLNEVTKSEGQIILFIDELHTLVGAGKAEGA--MDAGNMLKPALARGELHCIGAT 309
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 979895810 396 TLNEYQKYIEKDAALERRFQPVFVPEPSVEQTIVILRGLRDSLEAHHQVTFADDAFVAAAEFADRYITSRFLPDKAIDLI 475
Cdd:TIGR03346 310 TLDEYRKYIEKDAALERRFQPVFVDEPSVEDTISILRGLKERYEVHHGVRITDPAIVAAATLSHRYITDRFLPDKAIDLI 389
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 979895810 476 DQAAARVRIGATSRPVDIQEGEAQIAQL-------KREQDYAtSRKRFD-----------EAKQFEEQINAKQKSVDEM- 536
Cdd:TIGR03346 390 DEAAARIRMEIDSKPEELDELDRRIIQLeierealKKEKDEA-SKKRLEdlekeladleeEYAELEEQWKAEKASIQGIq 468
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 979895810 537 ---------------------------------------MEAWQRKTGSETL-----EVTVESVAEVVSRLTGIPVSELT 572
Cdd:TIGR03346 469 qikeeieqvrleleqaeregdlakaaelqygklpelekqLQAAEQKLGEEQNrllreEVTAEEIAEVVSRWTGIPVSKML 548
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 979895810 573 QEERQKLLKMEEQLRERVVGQSDAVVAVSDAVRLSRAGLGQTHRPIATFLFLGPTGVGKTELAKALAETVFGDEQAIIRI 652
Cdd:TIGR03346 549 EGEREKLLHMEEELHERVVGQDEAVEAVSDAIRRSRAGLSDPNRPIGSFLFLGPTGVGKTELAKALAEFLFDSEDAMVRI 628
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 979895810 653 DMSEYMERHAVARLIGAPPGYVGYDEGGQLTERVRRRPYSVILLDEIEKAHPDVYNVLLQVFDDGRLTDGKGRVVDFSNT 732
Cdd:TIGR03346 629 DMSEYMEKHSVARLIGAPPGYVGYEEGGQLTEAVRRRPYSVVLFDEVEKAHPDVFNVLLQVLDDGRLTDGQGRTVDFRNT 708
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 979895810 733 IIIATSNLGAAIIMDnltQPEAARKTdkAIREELMQVLKGHFRPEFLNRIDEVIVFHALSKENIRSIVQIQLDRVIRTAA 812
Cdd:TIGR03346 709 VIIMTSNLGSDFIQE---LAGGDDYE--EMREAVMEVLRAHFRPEFLNRIDEIVVFHPLGREQIARIVEIQLGRLRKRLA 783
|
810 820 830 840 850 860
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 979895810 813 AQDITLVMGDSLVEHLTEAGYQPEFGARELKRQIRQTIETRLAKEILADRLKSGDKCEVDYDKD 876
Cdd:TIGR03346 784 ERKITLELSDAALDFLAEAGYDPVYGARPLKRAIQREIENPLAKKILAGEVAPGDTIRVDVEGG 847
|
|
| clpC |
CHL00095 |
Clp protease ATP binding subunit |
84-878 |
0e+00 |
|
Clp protease ATP binding subunit
Pssm-ID: 214361 [Multi-domain] Cd Length: 821 Bit Score: 822.76 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 979895810 84 FSEQTLELLQRAAEKAHELRRSELDSEHLLYAL--ADTDVCAALLKELKLSPQDIRSYIDEHAHTGTADPDApldKLSIS 161
Cdd:CHL00095 5 FTEKAIKVIMLSQEEARRLGHNFVGTEQILLGLigEGTGIAARALKSMGVTLKDARIEVEKIIGRGTGFVAV---EIPFT 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 979895810 162 PRVKKAVQYAFQASRDLGHSYIGPEHLLIGLASVPDSVAGTLLKKYGVTPEALRQKVVKVVGKGAEDGRVDAPTG--TPN 239
Cdd:CHL00095 82 PRAKRVLEMSLEEARDLGHNYIGTEHLLLALLEEGEGVAARVLENLGVDLSKIRSLILNLIGEIIEAILGAEQSRskTPT 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 979895810 240 LDKFGRDLTAIARQGKLDPVLGRAQEIESTIEVLARRKKNNPVLIGEPGVGKTAIVEGLAQRIVNGDVPEVLRDKRLVEV 319
Cdd:CHL00095 162 LEEFGTNLTKEAIDGNLDPVIGREKEIERVIQILGRRTKNNPILIGEPGVGKTAIAEGLAQRIVNRDVPDILEDKLVITL 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 979895810 320 NINSMVAGAKYRGEFEERAKQLIDEVTaKQDELILFIDELHTIVGAGQGGGEggLDIANVLKPALARGELSLIGATTLNE 399
Cdd:CHL00095 242 DIGLLLAGTKYRGEFEERLKRIFDEIQ-ENNNIILVIDEVHTLIGAGAAEGA--IDAANILKPALARGELQCIGATTLDE 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 979895810 400 YQKYIEKDAALERRFQPVFVPEPSVEQTIVILRGLRDSLEAHHQVTFADDAFVAAAEFADRYITSRFLPDKAIDLIDQAA 479
Cdd:CHL00095 319 YRKHIEKDPALERRFQPVYVGEPSVEETIEILFGLRSRYEKHHNLSISDKALEAAAKLSDQYIADRFLPDKAIDLLDEAG 398
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 979895810 480 ARVRIGATSRPVDIQEGEAQIAQLKREQDYATSRKRFDEAKQFEE-------QINAKQKSVDEMMEAWQrktgsETLEVT 552
Cdd:CHL00095 399 SRVRLINSRLPPAARELDKELREILKDKDEAIREQDFETAKQLRDremevraQIAAIIQSKKTEEEKRL-----EVPVVT 473
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 979895810 553 VESVAEVVSRLTGIPVSELTQEERQKLLKMEEQLRERVVGQSDAVVAVSDAVRLSRAGLGQTHRPIATFLFLGPTGVGKT 632
Cdd:CHL00095 474 EEDIAEIVSAWTGIPVNKLTKSESEKLLHMEETLHKRIIGQDEAVVAVSKAIRRARVGLKNPNRPIASFLFSGPTGVGKT 553
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 979895810 633 ELAKALAETVFGDEQAIIRIDMSEYMERHAVARLIGAPPGYVGYDEGGQLTERVRRRPYSVILLDEIEKAHPDVYNVLLQ 712
Cdd:CHL00095 554 ELTKALASYFFGSEDAMIRLDMSEYMEKHTVSKLIGSPPGYVGYNEGGQLTEAVRKKPYTVVLFDEIEKAHPDIFNLLLQ 633
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 979895810 713 VFDDGRLTDGKGRVVDFSNTIIIATSNLGAAIIMDN-------LTQPEAARKTDKAIREELMQVLKGHFRPEFLNRIDEV 785
Cdd:CHL00095 634 ILDDGRLTDSKGRTIDFKNTLIIMTSNLGSKVIETNsgglgfeLSENQLSEKQYKRLSNLVNEELKQFFRPEFLNRLDEI 713
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 979895810 786 IVFHALSKENIRSIVQIQLDRVIRTAAAQDITLVMGDSLVEHLTEAGYQPEFGARELKRQIRQTIETRLAKEILADRLKS 865
Cdd:CHL00095 714 IVFRQLTKNDVWEIAEIMLKNLFKRLNEQGIQLEVTERIKTLLIEEGYNPLYGARPLRRAIMRLLEDPLAEEVLSFKIKP 793
|
810
....*....|...
gi 979895810 866 GDKCEVDYDKDSD 878
Cdd:CHL00095 794 GDIIIVDVNDEKE 806
|
|
| PRK10865 |
PRK10865 |
ATP-dependent chaperone ClpB; |
203-877 |
0e+00 |
|
ATP-dependent chaperone ClpB;
Pssm-ID: 182791 [Multi-domain] Cd Length: 857 Bit Score: 713.16 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 979895810 203 LLKKYGVTPEALRQKVVKVVG------KGAEDGRvdaptgtPNLDKFGRDLTAIARQGKLDPVLGRAQEIESTIEVLARR 276
Cdd:PRK10865 125 ILKAAGATTANITQAIEQMRGgesvndQGAEDQR-------QALKKYTIDLTERAEQGKLDPVIGRDEEIRRTIQVLQRR 197
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 979895810 277 KKNNPVLIGEPGVGKTAIVEGLAQRIVNGDVPEVLRDKRLVEVNINSMVAGAKYRGEFEERAKQLIDEVTAKQDELILFI 356
Cdd:PRK10865 198 TKNNPVLIGEPGVGKTAIVEGLAQRIINGEVPEGLKGRRVLALDMGALVAGAKYRGEFEERLKGVLNDLAKQEGNVILFI 277
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 979895810 357 DELHTIVGAGQGGGEggLDIANVLKPALARGELSLIGATTLNEYQKYIEKDAALERRFQPVFVPEPSVEQTIVILRGLRD 436
Cdd:PRK10865 278 DELHTMVGAGKADGA--MDAGNMLKPALARGELHCVGATTLDEYRQYIEKDAALERRFQKVFVAEPSVEDTIAILRGLKE 355
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 979895810 437 SLEAHHQVTFADDAFVAAAEFADRYITSRFLPDKAIDLIDQAAARVRIGATSRPVDIQEGEAQIAQLKREQDyaTSRKRF 516
Cdd:PRK10865 356 RYELHHHVQITDPAIVAAATLSHRYIADRQLPDKAIDLIDEAASSIRMQIDSKPEELDRLDRRIIQLKLEQQ--ALMKES 433
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 979895810 517 DEAKQ-----FEEQINAKQKSVDEMMEAWQRK----TGSETLE------------------------------------- 550
Cdd:PRK10865 434 DEASKkrldmLNEELSDKERQYSELEEEWKAEkaslSGTQTIKaeleqakiaieqarrvgdlarmselqygkipelekql 513
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 979895810 551 -----------------VTVESVAEVVSRLTGIPVSELTQEERQKLLKMEEQLRERVVGQSDAVVAVSDAVRLSRAGLGQ 613
Cdd:PRK10865 514 aaatqlegktmrllrnkVTDAEIAEVLARWTGIPVSRMLESEREKLLRMEQELHHRVIGQNEAVEAVSNAIRRSRAGLSD 593
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 979895810 614 THRPIATFLFLGPTGVGKTELAKALAETVFGDEQAIIRIDMSEYMERHAVARLIGAPPGYVGYDEGGQLTERVRRRPYSV 693
Cdd:PRK10865 594 PNRPIGSFLFLGPTGVGKTELCKALANFMFDSDDAMVRIDMSEFMEKHSVSRLVGAPPGYVGYEEGGYLTEAVRRRPYSV 673
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 979895810 694 ILLDEIEKAHPDVYNVLLQVFDDGRLTDGKGRVVDFSNTIIIATSNLGAAIIMDNLTQPEAARktdkaIREELMQVLKGH 773
Cdd:PRK10865 674 ILLDEVEKAHPDVFNILLQVLDDGRLTDGQGRTVDFRNTVVIMTSNLGSDLIQERFGELDYAH-----MKELVLGVVSHN 748
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 979895810 774 FRPEFLNRIDEVIVFHALSKENIRSIVQIQLDRVIRTAAAQDITLVMGDSLVEHLTEAGYQPEFGARELKRQIRQTIETR 853
Cdd:PRK10865 749 FRPEFINRIDEVVVFHPLGEQHIASIAQIQLQRLYKRLEERGYEIHISDEALKLLSENGYDPVYGARPLKRAIQQQIENP 828
|
730 740
....*....|....*....|....
gi 979895810 854 LAKEILADRLKSGDKCEVDYDKDS 877
Cdd:PRK10865 829 LAQQILSGELVPGKVIRLEVNDDR 852
|
|
| VI_ClpV1 |
TIGR03345 |
type VI secretion ATPase, ClpV1 family; Members of this protein family are homologs of ClpB, ... |
92-859 |
0e+00 |
|
type VI secretion ATPase, ClpV1 family; Members of this protein family are homologs of ClpB, an ATPase associated with chaperone-related functions. These ClpB homologs, designated ClpV1, are a key component of the bacterial pathogenicity-associated type VI secretion system. [Protein fate, Protein and peptide secretion and trafficking, Cellular processes, Pathogenesis]
Pssm-ID: 274528 [Multi-domain] Cd Length: 852 Bit Score: 691.30 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 979895810 92 LQRAAEKAHELRRSELDSEHLLYAL---ADTDVcAALLKELKLSP----QDIRSYIDEHAHTGTADPDapldklsISPRV 164
Cdd:TIGR03345 9 LEQAAALCVARGHPEVELEHWLLALldqPDSDL-AAILRHFGVDLgrlkADLARALDKLPRGNTRTPV-------FSPHL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 979895810 165 KKAVQYAFQ-ASRDLGHSYIGPEHLLIGLASVPD------SVAGTLLKkygVTPEALRQKVVKVVGKGAED--------- 228
Cdd:TIGR03345 81 VELLQEAWLlASLELGDGRIRSGHLLLALLTDPElrrllgSISPELAK---IDREALREALPALVEGSAEAsaaaadaap 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 979895810 229 -GRVDAPTGTPNLDKFGRDLTAIARQGKLDPVLGRAQEIESTIEVLARRKKNNPVLIGEPGVGKTAIVEGLAQRIVNGDV 307
Cdd:TIGR03345 158 aGAAAGAAGTSALDQYTTDLTAQAREGKIDPVLGRDDEIRQMIDILLRRRQNNPILTGEAGVGKTAVVEGLALRIAAGDV 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 979895810 308 PEVLRDKRLVEVNINSMVAGAKYRGEFEERAKQLIDEVTAKQDELILFIDELHTIVGAGQGGGEggLDIANVLKPALARG 387
Cdd:TIGR03345 238 PPALRNVRLLSLDLGLLQAGASVKGEFENRLKSVIDEVKASPQPIILFIDEAHTLIGAGGQAGQ--GDAANLLKPALARG 315
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 979895810 388 ELSLIGATTLNEYQKYIEKDAALERRFQPVFVPEPSVEQTIVILRGLRDSLEAHHQVTFADDAFVAAAEFADRYITSRFL 467
Cdd:TIGR03345 316 ELRTIAATTWAEYKKYFEKDPALTRRFQVVKVEEPDEETAIRMLRGLAPVLEKHHGVLILDEAVVAAVELSHRYIPGRQL 395
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 979895810 468 PDKAIDLIDQAAARVRIGATSRPVDIQEGEAQIAQLKREQDYATSRKRFDEA-----KQFEEQINAKQKSVDEMMEAWQR 542
Cdd:TIGR03345 396 PDKAVSLLDTACARVALSQNATPAALEDLRRRIAALELELDALEREAALGADhderlAELRAELAALEAELAALEARWQQ 475
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 979895810 543 K------------------------------------------TGSETL---EVTVESVAEVVSRLTGIPVSELTQEERQ 577
Cdd:TIGR03345 476 EkelveailalraeleadadapaddddalraqlaeleaalasaQGEEPLvfpEVDAQAVAEVVADWTGIPVGRMVRDEIE 555
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 979895810 578 KLLKMEEQLRERVVGQSDAVVAVSDAVRLSRAGLGQTHRPIATFLFLGPTGVGKTELAKALAETVFGDEQAIIRIDMSEY 657
Cdd:TIGR03345 556 AVLSLPDRLAERVIGQDHALEAIAERIRTARAGLEDPRKPLGVFLLVGPSGVGKTETALALAELLYGGEQNLITINMSEF 635
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 979895810 658 MERHAVARLIGAPPGYVGYDEGGQLTERVRRRPYSVILLDEIEKAHPDVYNVLLQVFDDGRLTDGKGRVVDFSNTIIIAT 737
Cdd:TIGR03345 636 QEAHTVSRLKGSPPGYVGYGEGGVLTEAVRRKPYSVVLLDEVEKAHPDVLELFYQVFDKGVMEDGEGREIDFKNTVILLT 715
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 979895810 738 SNLGAAIIMDNLTQPEAARKTD---KAIREELMQvlkgHFRPEFLNRIdEVIVFHALSKENIRSIVQIQLDRVI-RTAAA 813
Cdd:TIGR03345 716 SNAGSDLIMALCADPETAPDPEallEALRPELLK----VFKPAFLGRM-TVIPYLPLDDDVLAAIVRLKLDRIArRLKEN 790
|
810 820 830 840
....*....|....*....|....*....|....*....|....*.
gi 979895810 814 QDITLVMGDSLVEHLTEAGYQPEFGARELKRQIRQTIETRLAKEIL 859
Cdd:TIGR03345 791 HGAELVYSEALVEHIVARCTEVESGARNIDAILNQTLLPELSRQIL 836
|
|
| ClpA |
TIGR02639 |
ATP-dependent Clp protease ATP-binding subunit clpA; [Protein fate, Degradation of proteins, ... |
84-872 |
0e+00 |
|
ATP-dependent Clp protease ATP-binding subunit clpA; [Protein fate, Degradation of proteins, peptides, and glycopeptides]
Pssm-ID: 274241 [Multi-domain] Cd Length: 730 Bit Score: 677.90 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 979895810 84 FSEQTLELLQRAAEKAHELRRSELDSEHLLYALADTDVCAALLKE----LKLSPQDIRSYIDEHAHTGTADPDA-PLDKL 158
Cdd:TIGR02639 1 ISEELERILSDALEEAKERRHEFVTLEHLLLALLDDNEAIEILEEcggdVELLRKRLEDYLEENLPVIPEDIDEePEQTV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 979895810 159 SISpRVkkaVQYAFQASRDLGHSYIGPEHLLIGLASVPDSVAGTLLKKYGVTPEALRQKVVKVVGKGAEDGRVDAPTGTP 238
Cdd:TIGR02639 81 GVQ-RV---IQRALLHVKSAGKKEIDIGDLLVALFDEEDSHASYFLKSQGITRLDILNYISHGISKDDGKDQLGEEAGKE 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 979895810 239 N------LDKFGRDLTAIARQGKLDPVLGRAQEIESTIEVLARRKKNNPVLIGEPGVGKTAIVEGLAQRIVNGDVPEVLR 312
Cdd:TIGR02639 157 EekgqdaLEKYTVDLTEKAKNGKIDPLIGREDELERTIQVLCRRKKNNPLLVGEPGVGKTAIVEGLALRIAEGKVPERLK 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 979895810 313 DKRLVEVNINSMVAGAKYRGEFEERAKQLIDEVTaKQDELILFIDELHTIVGAGQGGGEGgLDIANVLKPALARGELSLI 392
Cdd:TIGR02639 237 NAKIYSLDMGTLLAGTKYRGDFEERLKAVVSEIE-KEPNAILFIDEIHTIVGAGATSGGS-MDASNLLKPALSSGKIRCI 314
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 979895810 393 GATTLNEYQKYIEKDAALERRFQPVFVPEPSVEQTIVILRGLRDSLEAHHQVTFADDAFVAAAEFADRYITSRFLPDKAI 472
Cdd:TIGR02639 315 GSTTYEEYKNHFEKDRALSRRFQKIDVGEPSIEETVKILKGLKEQYEEFHHVKYSDEALEAAVELSARYINDRFLPDKAI 394
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 979895810 473 DLIDQAAARVRIGATSRPvdiqegeaqiaqlkreqdyatsrkrfdeakqfeeqiNAKqksvdemmeawqrktgsetleVT 552
Cdd:TIGR02639 395 DVIDEAGAAFRLRPKAKK------------------------------------KAN---------------------VN 417
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 979895810 553 VESVAEVVSRLTGIPVSELTQEERQKLLKMEEQLRERVVGQSDAVVAVSDAVRLSRAGLGQTHRPIATFLFLGPTGVGKT 632
Cdd:TIGR02639 418 VKDIENVVAKMAKIPVKTVSSDDREQLKNLEKNLKAKIFGQDEAIDQLVSAIKRSRAGLGDPNKPVGSFLFVGPTGVGKT 497
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 979895810 633 ELAKALAETVfgdEQAIIRIDMSEYMERHAVARLIGAPPGYVGYDEGGQLTERVRRRPYSVILLDEIEKAHPDVYNVLLQ 712
Cdd:TIGR02639 498 ELAKQLAEEL---GVHLLRFDMSEYMEKHTVSRLIGSPPGYVGFEQGGLLTDAVRKHPHCVLLLDEIEKAHPDIYNILLQ 574
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 979895810 713 VFDDGRLTDGKGRVVDFSNTIIIATSNLGAAIIMDN---LTQPEAARKTDKAIreelmqvlKGHFRPEFLNRIDEVIVFH 789
Cdd:TIGR02639 575 VMDYATLTDNNGRKADFRNVILIMTSNAGASEMSKPpigFGGENRESKSLKAI--------KKLFSPEFRNRLDAIIHFN 646
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 979895810 790 ALSKENIRSIVQIQLDRVIRTAAAQDITLVMGDSLVEHLTEAGYQPEFGARELKRQIRQTIETRLAKEILADRLKSGDKC 869
Cdd:TIGR02639 647 DLSEEMAEKIVKKFLDELQDQLNEKNIELELTDDAKKYLAEKGYDEEFGARPLARVIQEEIKKPLSDEILFGKLKKGGSV 726
|
...
gi 979895810 870 EVD 872
Cdd:TIGR02639 727 KIS 729
|
|
| clpA |
PRK11034 |
ATP-dependent Clp protease ATP-binding subunit; Provisional |
87-883 |
4.84e-177 |
|
ATP-dependent Clp protease ATP-binding subunit; Provisional
Pssm-ID: 236828 [Multi-domain] Cd Length: 758 Bit Score: 532.49 E-value: 4.84e-177
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 979895810 87 QTLEL-LQRAAEKAHELRRSELDSEHLLYALADTD-------VCAALLKELKlspQDIRSYIDEHAHTGTADPDAPLDKL 158
Cdd:PRK11034 4 QELELsLNMAFARAREHRHEFMTVEHLLLALLSNPsarealeACSVDLVALR---QELEAFIEQTTPVLPASEEERDTQP 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 979895810 159 SIS-PRVKKAVQYAFQASrdlGHSYIGPEHLLIGLASVPDSVAGTLLKKYGVTpealRQKVVKVVGKGA---EDGRVDAP 234
Cdd:PRK11034 81 TLSfQRVLQRAVFHVQSS---GRSEVTGANVLVAIFSEQESQAAYLLRKHEVS----RLDVVNFISHGTrkdEPSQSSDP 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 979895810 235 TGTPN----------LDKFGRDLTAIARQGKLDPVLGRAQEIESTIEVLARRKKNNPVLIGEPGVGKTAIVEGLAQRIVN 304
Cdd:PRK11034 154 GSQPNseeqaggeerMENFTTNLNQLARVGGIDPLIGREKELERAIQVLCRRRKNNPLLVGESGVGKTAIAEGLAWRIVQ 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 979895810 305 GDVPEVLRDKRLVEVNINSMVAGAKYRGEFEERAKQLIDEVtAKQDELILFIDELHTIVgAGQGGGEGGLDIANVLKPAL 384
Cdd:PRK11034 234 GDVPEVMADCTIYSLDIGSLLAGTKYRGDFEKRFKALLKQL-EQDTNSILFIDEIHTII-GAGAASGGQVDAANLIKPLL 311
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 979895810 385 ARGELSLIGATTLNEYQKYIEKDAALERRFQPVFVPEPSVEQTIVILRGLRDSLEAHHQVTFADDAFVAAAEFADRYITS 464
Cdd:PRK11034 312 SSGKIRVIGSTTYQEFSNIFEKDRALARRFQKIDITEPSIEETVQIINGLKPKYEAHHDVRYTAKAVRAAVELAVKYIND 391
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 979895810 465 RFLPDKAIDLIDQAAARVRIGATSRpvdiqegeaqiaqlkreqdyatsrkrfdeakqfeeqinakqksvdemmeawQRKT 544
Cdd:PRK11034 392 RHLPDKAIDVIDEAGARARLMPVSK---------------------------------------------------RKKT 420
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 979895810 545 gsetleVTVESVAEVVSRLTGIPVSELTQEERQKLLKMEEQLRERVVGQSDAVVAVSDAVRLSRAGLGQTHRPIATFLFL 624
Cdd:PRK11034 421 ------VNVADIESVVARIARIPEKSVSQSDRDTLKNLGDRLKMLVFGQDKAIEALTEAIKMSRAGLGHEHKPVGSFLFA 494
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 979895810 625 GPTGVGKTELAKALAETVfGDEqaIIRIDMSEYMERHAVARLIGAPPGYVGYDEGGQLTERVRRRPYSVILLDEIEKAHP 704
Cdd:PRK11034 495 GPTGVGKTEVTVQLSKAL-GIE--LLRFDMSEYMERHTVSRLIGAPPGYVGFDQGGLLTDAVIKHPHAVLLLDEIEKAHP 571
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 979895810 705 DVYNVLLQVFDDGRLTDGKGRVVDFSNTIIIATSNLGAAiimdnltqpEAARKTDKAIRE----ELMQVLKGHFRPEFLN 780
Cdd:PRK11034 572 DVFNLLLQVMDNGTLTDNNGRKADFRNVVLVMTTNAGVR---------ETERKSIGLIHQdnstDAMEEIKKIFTPEFRN 642
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 979895810 781 RIDEVIVFHALSKENIRSIV-------QIQLDrvirtaaAQDITLVMGDSLVEHLTEAGYQPEFGARELKRQIRQTIETR 853
Cdd:PRK11034 643 RLDNIIWFDHLSTDVIHQVVdkfivelQAQLD-------QKGVSLEVSQEARDWLAEKGYDRAMGARPMARVIQDNLKKP 715
|
810 820 830
....*....|....*....|....*....|
gi 979895810 854 LAKEILADRLKSGDKCEVDYDKDSDEVKFN 883
Cdd:PRK11034 716 LANELLFGSLVDGGQVTVALDKEKNELTYG 745
|
|
| RecA-like_ClpB_Hsp104-like |
cd19499 |
Chaperone protein ClpB/Hsp104 subfamily; Bacterial Caseinolytic peptidase B (ClpB) and ... |
578-788 |
2.38e-105 |
|
Chaperone protein ClpB/Hsp104 subfamily; Bacterial Caseinolytic peptidase B (ClpB) and eukaryotic Heat shock protein 104 (Hsp104) are ATP-dependent molecular chaperones and essential proteins of the heat-shock response. ClpB/Hsp104 ATPases, in concert with the DnaK/Hsp70 chaperone system, disaggregate and reactivate aggregated proteins. This RecA-like_ClpB_Hsp104_like subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.
Pssm-ID: 410907 [Multi-domain] Cd Length: 178 Bit Score: 324.52 E-value: 2.38e-105
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 979895810 578 KLLKMEEQLRERVVGQSDAVVAVSDAVRLSRAGLGQTHRPIATFLFLGPTGVGKTELAKALAETVFGDEQAIIRIDMSEY 657
Cdd:cd19499 1 KLLNLEERLHERVVGQDEAVKAVSDAIRRARAGLSDPNRPIGSFLFLGPTGVGKTELAKALAELLFGDEDNLIRIDMSEY 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 979895810 658 MERHAVARLIGAPPGYVGYDEGGQLTERVRRRPYSVILLDEIEKAHPDVYNVLLQVFDDGRLTDGKGRVVDFSNTIIIAT 737
Cdd:cd19499 81 MEKHSVSRLIGAPPGYVGYTEGGQLTEAVRRKPYSVVLLDEIEKAHPDVQNLLLQVLDDGRLTDSHGRTVDFKNTIIIMT 160
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 979895810 738 SNlgaaiimdnltqpeaarktdkaireelmqvlkgHFRPEFLNRIDEVIVF 788
Cdd:cd19499 161 SN---------------------------------HFRPEFLNRIDEIVVF 178
|
|
| AAA_2 |
pfam07724 |
AAA domain (Cdc48 subfamily); This Pfam entry includes some of the AAA proteins not detected ... |
616-785 |
1.81e-91 |
|
AAA domain (Cdc48 subfamily); This Pfam entry includes some of the AAA proteins not detected by the pfam00004 model.
Pssm-ID: 400187 [Multi-domain] Cd Length: 168 Bit Score: 287.17 E-value: 1.81e-91
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 979895810 616 RPIATFLFLGPTGVGKTELAKALAETVFGDEQAIIRIDMSEYMERHAVARLIGAPPGYVGYDEGGQLTERVRRRPYSVIL 695
Cdd:pfam07724 1 RPIGSFLFLGPTGVGKTELAKALAELLFGDERALIRIDMSEYMEEHSVSRLIGAPPGYVGYEEGGQLTEAVRRKPYSIVL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 979895810 696 LDEIEKAHPDVYNVLLQVFDDGRLTDGKGRVVDFSNTIIIATSNLGAAIIMDNLTQPEaaRKTDKAIREELMQVLKGHFR 775
Cdd:pfam07724 81 IDEIEKAHPGVQNDLLQILEGGTLTDKQGRTVDFKNTLFIMTGNFGSEKISDASRLGD--SPDYELLKEEVMDLLKKGFI 158
|
170
....*....|
gi 979895810 776 PEFLNRIDEV 785
Cdd:pfam07724 159 PEFLGRLPII 168
|
|
| AAA_lid_9 |
pfam17871 |
AAA lid domain; This entry represents the alpha helical AAA+ lid domain that is found to the ... |
423-525 |
1.08e-29 |
|
AAA lid domain; This entry represents the alpha helical AAA+ lid domain that is found to the C-terminus of AAA domains.
Pssm-ID: 465544 [Multi-domain] Cd Length: 104 Bit Score: 113.35 E-value: 1.08e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 979895810 423 SVEQTIVILRGLRDSLEAHHQVTFADDAFVAAAEFADRYITSRFLPDKAIDLIDQAAARVRIGATSRPVDIQEGEAQIAQ 502
Cdd:pfam17871 1 SVEEAIEILRGLKPKYEKHHGVRISDEALEAAVKLSKRYITDRFLPDKAIDLLDEACARVRLSQESKPEELEDLERELAK 80
|
90 100
....*....|....*....|...
gi 979895810 503 LKREQDYATSRKRFDEAKQFEEQ 525
Cdd:pfam17871 81 LEIEKEALEREQDFEKAERLAKL 103
|
|
| ClpB_D2-small |
pfam10431 |
C-terminal, D2-small domain, of ClpB protein; This is the C-terminal domain of ClpB protein, ... |
791-871 |
2.52e-24 |
|
C-terminal, D2-small domain, of ClpB protein; This is the C-terminal domain of ClpB protein, referred to as the D2-small domain, and is a mixed alpha-beta structure. Compared with the D1-small domain (included in AAA, pfam00004) it lacks the long coiled-coil insertion, and instead of helix C4 contains a beta-strand (e3) that is part of a three stranded beta-pleated sheet. In Thermophilus the whole protein forms a hexamer with the D1-small and D2-small domains located on the outside of the hexamer, with the long coiled-coil being exposed on the surface. The D2-small domain is essential for oligomerization, forming a tight interface with the D2-large domain of a neighbouring subunit and thereby providing enough binding energy to stabilize the functional assembly. The domain is associated with two Clp_N, pfam02861, at the N-terminus as well as AAA, pfam00004 and AAA_2, pfam07724.
Pssm-ID: 463090 [Multi-domain] Cd Length: 81 Bit Score: 97.48 E-value: 2.52e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 979895810 791 LSKENIRSIVQIQLDRVIRTAAAQDITLVMGDSLVEHLTEAGYQPEFGARELKRQIRQTIETRLAKEILADRLKSGDKCE 870
Cdd:pfam10431 1 LSKEELRKIVDLQLKELQKRLAERGITLELTDAAKDWLAEKGYDPEYGARPLRRAIQREIEDPLAEEILSGELKEGDTVR 80
|
.
gi 979895810 871 V 871
Cdd:pfam10431 81 V 81
|
|
| ClpB_D2-small |
smart01086 |
C-terminal, D2-small domain, of ClpB protein; This is the C-terminal domain of ClpB protein, ... |
791-880 |
1.46e-21 |
|
C-terminal, D2-small domain, of ClpB protein; This is the C-terminal domain of ClpB protein, referred to as the D2-small domain, and is a mixed alpha-beta structure. Compared with the D1-small domain (included in AAA) it lacks the long coiled-coil insertion, and instead of helix C4 contains a beta-strand (e3) that is part of a three stranded beta-pleated sheet. In Thermophilus the whole protein forms a hexamer with the D1-small and D2-small domains located on the outside of the hexamer, with the long coiled-coil being exposed on the surface. The D2-small domain is essential for oligomerisation, forming a tight interface with the D2-large domain of a neighbouring subunit and thereby providing enough binding energy to stabilise the functional assembly. The domain is associated with two Clp_N at the N-terminus as well as AAA and AAA_2.
Pssm-ID: 198154 [Multi-domain] Cd Length: 90 Bit Score: 89.81 E-value: 1.46e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 979895810 791 LSKENIRSIVQIQLDRVIRTAAAQDITLVMGDSLVEHLTEAGYQPEFGARELKRQIRQTIETRLAKEILADRLKSGDKCE 870
Cdd:smart01086 1 LDKEDLVRIVDLPLNALQKRLAEKGITLEFTDEALDWLAEKGYDPKYGARPLRRIIQRELEDPLAELILSGELKDGDTVV 80
|
90
....*....|
gi 979895810 871 VDYDKDSDEV 880
Cdd:smart01086 81 VDVDDGELVF 90
|
|
| AAA |
cd00009 |
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily ... |
261-422 |
1.63e-18 |
|
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC, RecA-like, VirD4-like, PilT-like, and SF1/2 helicases. Members of the AAA+ ATPases function as molecular chaperons, ATPase subunits of proteases, helicases, or nucleic-acid stimulated ATPases. The AAA+ proteins contain several distinct features in addition to the conserved alpha-beta-alpha core domain structure and the Walker A and B motifs of the P-loop NTPases.
Pssm-ID: 99707 [Multi-domain] Cd Length: 151 Bit Score: 83.35 E-value: 1.63e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 979895810 261 GRAQEIESTIEVLARRKKNNPVLIGEPGVGKTAIVEGLAQRIVNgdvpevlRDKRLVEVNINSMVAGAKYRGEFEERAKQ 340
Cdd:cd00009 2 GQEEAIEALREALELPPPKNLLLYGPPGTGKTTLARAIANELFR-------PGAPFLYLNASDLLEGLVVAELFGHFLVR 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 979895810 341 LIDEVTAKQDELILFIDELHTIVGAGQGGGEGGLDIANVLKPalARGELSLIGATTLNEyqkYIEKDAALERRFQPVFVP 420
Cdd:cd00009 75 LLFELAEKAKPGVLFIDEIDSLSRGAQNALLRVLETLNDLRI--DRENVRVIGATNRPL---LGDLDRALYDRLDIRIVI 149
|
..
gi 979895810 421 EP 422
Cdd:cd00009 150 PL 151
|
|
| AAA |
cd00009 |
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily ... |
591-748 |
1.78e-18 |
|
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC, RecA-like, VirD4-like, PilT-like, and SF1/2 helicases. Members of the AAA+ ATPases function as molecular chaperons, ATPase subunits of proteases, helicases, or nucleic-acid stimulated ATPases. The AAA+ proteins contain several distinct features in addition to the conserved alpha-beta-alpha core domain structure and the Walker A and B motifs of the P-loop NTPases.
Pssm-ID: 99707 [Multi-domain] Cd Length: 151 Bit Score: 83.35 E-value: 1.78e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 979895810 591 VGQSDAVVAVSDAVRLsraglgqthRPIATFLFLGPTGVGKTELAKALAETVFGDEQAIIRIDMSEYMERHAVARLIgap 670
Cdd:cd00009 1 VGQEEAIEALREALEL---------PPPKNLLLYGPPGTGKTTLARAIANELFRPGAPFLYLNASDLLEGLVVAELF--- 68
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 979895810 671 pgyvGYDEGGQLTERVRRRPYSVILLDEIEKAHPDVYNVLLQVFDDGRLTdgkgrVVDFSNTIIIATSNLGAAIIMDN 748
Cdd:cd00009 69 ----GHFLVRLLFELAEKAKPGVLFIDEIDSLSRGAQNALLRVLETLNDL-----RIDRENVRVIGATNRPLLGDLDR 137
|
|
| AAA |
smart00382 |
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ... |
620-745 |
3.36e-15 |
|
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.
Pssm-ID: 214640 [Multi-domain] Cd Length: 148 Bit Score: 73.56 E-value: 3.36e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 979895810 620 TFLFLGPTGVGKTELAKALAETVFGDEQAIIRIDMSEYMERHAVARLIGAPPGYVGYDEGGQ----LTERVRRRPYSVIL 695
Cdd:smart00382 4 VILIVGPPGSGKTTLARALARELGPPGGGVIYIDGEDILEEVLDQLLLIIVGGKKASGSGELrlrlALALARKLKPDVLI 83
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|
gi 979895810 696 LDEIEKAHPDVYNVLLQVFDDGRLTDGKGRvvdFSNTIIIATSNLGAAII 745
Cdd:smart00382 84 LDEITSLLDAEQEALLLLLEELRLLLLLKS---EKNLTVILTTNDEKDLG 130
|
|
| AAA_5 |
pfam07728 |
AAA domain (dynein-related subfamily); This Pfam entry includes some of the AAA proteins not ... |
621-739 |
1.83e-13 |
|
AAA domain (dynein-related subfamily); This Pfam entry includes some of the AAA proteins not detected by the pfam00004 model.
Pssm-ID: 400191 [Multi-domain] Cd Length: 135 Bit Score: 68.09 E-value: 1.83e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 979895810 621 FLFLGPTGVGKTELAKALAETVFGDEQAIIRidMSEYMERhavARLIGappgyvGYDEGGQLTERVRR------RPYSVI 694
Cdd:pfam07728 2 VLLVGPPGTGKTELAERLAAALSNRPVFYVQ--LTRDTTE---EDLFG------RRNIDPGGASWVDGplvraaREGEIA 70
|
90 100 110 120
....*....|....*....|....*....|....*....|....*...
gi 979895810 695 LLDEIEKAHPDVYNVLLQVFDDGRLT--DGKGRV-VDFSNTIIIATSN 739
Cdd:pfam07728 71 VLDEINRANPDVLNSLLSLLDERRLLlpDGGELVkAAPDGFRLIATMN 118
|
|
| Clp_N |
pfam02861 |
Clp amino terminal domain, pathogenicity island component; This short domain is found in one ... |
171-223 |
7.97e-13 |
|
Clp amino terminal domain, pathogenicity island component; This short domain is found in one or two copies at the amino terminus of ClpA and ClpB proteins from bacteria and eukaryotes. The function of these domains is uncertain but they may form a protein binding site. In many bacterial species, including E.coli, this region represents the N-terminus of one of the key components of the pathogenicity island complex that injects toxin from one bacterium into another.
Pssm-ID: 460724 [Multi-domain] Cd Length: 53 Bit Score: 63.69 E-value: 7.97e-13
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|...
gi 979895810 171 AFQASRDLGHSYIGPEHLLIGLASVPDSVAGTLLKKYGVTPEALRQKVVKVVG 223
Cdd:pfam02861 1 AQELARALGHQYIGTEHLLLALLEEDDGLAARLLKKAGVDLDALREAIEKLLG 53
|
|
| AAA |
pfam00004 |
ATPase family associated with various cellular activities (AAA); AAA family proteins often ... |
283-418 |
1.05e-11 |
|
ATPase family associated with various cellular activities (AAA); AAA family proteins often perform chaperone-like functions that assist in the assembly, operation, or disassembly of protein complexes.
Pssm-ID: 459627 [Multi-domain] Cd Length: 130 Bit Score: 63.00 E-value: 1.05e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 979895810 283 LIGEPGVGKTAIVEGLAQRIvngdvpevlrDKRLVEVNINSMVagAKYRGEFEERAKQLIDEVTAKQDeLILFIDELHTI 362
Cdd:pfam00004 3 LYGPPGTGKTTLAKAVAKEL----------GAPFIEISGSELV--SKYVGESEKRLRELFEAAKKLAP-CVIFIDEIDAL 69
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 979895810 363 VGA-GQGGGEGGLDIANVLKPALARGELS-----LIGATtlNEYQKYiekDAALERRFQPVF 418
Cdd:pfam00004 70 AGSrGSGGDSESRRVVNQLLTELDGFTSSnskviVIAAT--NRPDKL---DPALLGRFDRII 126
|
|
| RecA-like_protease |
cd19481 |
proteases similar to RecA; RecA-like NTPases. This family includes the NTP binding domain of ... |
595-745 |
1.14e-09 |
|
proteases similar to RecA; RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.
Pssm-ID: 410889 [Multi-domain] Cd Length: 158 Bit Score: 58.06 E-value: 1.14e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 979895810 595 DAVVAVSDAVRLSRAGLGqthrPIATFLFLGPTGVGKTELAKALA-ETVFGdeqaIIRIDMSEYMERHavarligappGY 673
Cdd:cd19481 7 EAVEAPRRGSRLRRYGLG----LPKGILLYGPPGTGKTLLAKALAgELGLP----LIVVKLSSLLSKY----------VG 68
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 979895810 674 VGYDEGGQLTERVRRRPYSVILLDEIEKAHPD------------VYNVLLQVFDDGRLTDgkgrvvdfsNTIIIATSNLG 741
Cdd:cd19481 69 ESEKNLRKIFERARRLAPCILFIDEIDAIGRKrdssgesgelrrVLNQLLTELDGVNSRS---------KVLVIAATNRP 139
|
....
gi 979895810 742 AAII 745
Cdd:cd19481 140 DLLD 143
|
|
| AAA |
smart00382 |
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ... |
277-419 |
1.45e-08 |
|
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.
Pssm-ID: 214640 [Multi-domain] Cd Length: 148 Bit Score: 54.69 E-value: 1.45e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 979895810 277 KKNNPVLIGEPGVGKTAIVEGLAQRIVNGDVPEVLRD-----KRLVEVNINSMVAGAKYRGEFEERAKQLIDEVtAKQDE 351
Cdd:smart00382 1 PGEVILIVGPPGSGKTTLARALARELGPPGGGVIYIDgedilEEVLDQLLLIIVGGKKASGSGELRLRLALALA-RKLKP 79
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 979895810 352 LILFIDELHTIVGAGQGGGEGGLDIANVLKPALARGELSLIGATTLNEyqkyIEKDAALERRFQPVFV 419
Cdd:smart00382 80 DVLILDEITSLLDAEQEALLLLLEELRLLLLLKSEKNLTVILTTNDEK----DLGPALLRRRFDRRIV 143
|
|
| AAA |
pfam00004 |
ATPase family associated with various cellular activities (AAA); AAA family proteins often ... |
622-739 |
4.53e-07 |
|
ATPase family associated with various cellular activities (AAA); AAA family proteins often perform chaperone-like functions that assist in the assembly, operation, or disassembly of protein complexes.
Pssm-ID: 459627 [Multi-domain] Cd Length: 130 Bit Score: 49.90 E-value: 4.53e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 979895810 622 LFLGPTGVGKTELAKALAETVFGDeqaIIRIDMSEymerhAVARLIGAPPGYVgydegGQLTERVRRRPYSVILLDEIEK 701
Cdd:pfam00004 2 LLYGPPGTGKTTLAKAVAKELGAP---FIEISGSE-----LVSKYVGESEKRL-----RELFEAAKKLAPCVIFIDEIDA 68
|
90 100 110 120
....*....|....*....|....*....|....*....|....*....
gi 979895810 702 AHP-----------DVYNVLLQVFDDGRltdgkgrvVDFSNTIIIATSN 739
Cdd:pfam00004 69 LAGsrgsggdsesrRVVNQLLTELDGFT--------SSNSKVIVIAATN 109
|
|
| COG1223 |
COG1223 |
Predicted ATPase, AAA+ superfamily [General function prediction only]; |
590-807 |
4.95e-07 |
|
Predicted ATPase, AAA+ superfamily [General function prediction only];
Pssm-ID: 440836 [Multi-domain] Cd Length: 246 Bit Score: 51.81 E-value: 4.95e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 979895810 590 VVGQSDAVVAVSDAVR-LSRAGLGQTHRPIAT--FLFLGPTGVGKTELAKALA-ETvfGDEQAIIRID--MSEYMERhAV 663
Cdd:COG1223 4 VVGQEEAKKKLKLIIKeLRRRENLRKFGLWPPrkILFYGPPGTGKTMLAEALAgEL--KLPLLTVRLDslIGSYLGE-TA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 979895810 664 ARLigappgyvgydegGQLTERVRRRPySVILLDEIE---------KAHPD---VYNVLLQVFDDGRltdgkgrvvdfSN 731
Cdd:COG1223 81 RNL-------------RKLFDFARRAP-CVIFFDEFDaiakdrgdqNDVGEvkrVVNALLQELDGLP-----------SG 135
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 979895810 732 TIIIATSNLGAAIimdnltqpeaarktDKAIReelmqvlkghfrpeflNRIDEVIVFHALSKENIRSIVQIQLDRV 807
Cdd:COG1223 136 SVVIAATNHPELL--------------DSALW----------------RRFDEVIEFPLPDKEERKEILELNLKKF 181
|
|
| MoxR |
COG0714 |
MoxR-like ATPase [General function prediction only]; MoxR-like ATPase is part of the Pathway ... |
581-739 |
7.23e-07 |
|
MoxR-like ATPase [General function prediction only]; MoxR-like ATPase is part of the Pathway/BioSystem: Cobalamine/B12 biosynthesis
Pssm-ID: 440478 [Multi-domain] Cd Length: 292 Bit Score: 52.09 E-value: 7.23e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 979895810 581 KMEEQLRERVVGQSDAVVAVSDAVRLsraglgqtHRPIatfLFLGPTGVGKTELAKALAETVFGDeqaIIRI----DMse 656
Cdd:COG0714 5 RLRAEIGKVYVGQEELIELVLIALLA--------GGHL---LLEGVPGVGKTTLAKALARALGLP---FIRIqftpDL-- 68
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 979895810 657 yMErhavARLIGAppgYVgYDEGGQlTERVRRRPY--SVILLDEIEKAHPDVYNVLLQVFDDGRLT-DGKGRVVD--Fsn 731
Cdd:COG0714 69 -LP----SDILGT---YI-YDQQTG-EFEFRPGPLfaNVLLADEINRAPPKTQSALLEAMEERQVTiPGGTYKLPepF-- 136
|
....*...
gi 979895810 732 tIIIATSN 739
Cdd:COG0714 137 -LVIATQN 143
|
|
| AAA_5 |
pfam07728 |
AAA domain (dynein-related subfamily); This Pfam entry includes some of the AAA proteins not ... |
282-414 |
9.90e-07 |
|
AAA domain (dynein-related subfamily); This Pfam entry includes some of the AAA proteins not detected by the pfam00004 model.
Pssm-ID: 400191 [Multi-domain] Cd Length: 135 Bit Score: 48.83 E-value: 9.90e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 979895810 282 VLIGEPGVGKTAIVEGLAQRIVNGDVPEVLRDKRLVEVNInsmvagaKYRGEFEERAKQLIDE--VTAKQDELILFIDEL 359
Cdd:pfam07728 3 LLVGPPGTGKTELAERLAAALSNRPVFYVQLTRDTTEEDL-------FGRRNIDPGGASWVDGplVRAAREGEIAVLDEI 75
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 979895810 360 HTIvgagqgggegGLDIANVLKPALARGELSL---------------IGATTLNEYQKYIEKDAALERRF 414
Cdd:pfam07728 76 NRA----------NPDVLNSLLSLLDERRLLLpdggelvkaapdgfrLIATMNPLDRGLNELSPALRSRF 135
|
|
| AAA_22 |
pfam13401 |
AAA domain; |
619-718 |
1.58e-06 |
|
AAA domain;
Pssm-ID: 379165 [Multi-domain] Cd Length: 129 Bit Score: 48.11 E-value: 1.58e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 979895810 619 ATFLFL-GPTGVGKTELAKALAETVFGDEQAIIRIDMSEYME----RHAVARLIGAPPgyVGYDEGGQLTERV-----RR 688
Cdd:pfam13401 5 AGILVLtGESGTGKTTLLRRLLEQLPEVRDSVVFVDLPSGTSpkdlLRALLRALGLPL--SGRLSKEELLAALqqlllAL 82
|
90 100 110
....*....|....*....|....*....|
gi 979895810 689 RPYSVILLDEIEKAHPDVYNVLLQVFDDGR 718
Cdd:pfam13401 83 AVAVVLIIDEAQHLSLEALEELRDLLNLSS 112
|
|
| SpoVK |
COG0464 |
AAA+-type ATPase, SpoVK/Ycf46/Vps4 family [Cell wall/membrane/envelope biogenesis, Cell cycle ... |
438-830 |
4.18e-06 |
|
AAA+-type ATPase, SpoVK/Ycf46/Vps4 family [Cell wall/membrane/envelope biogenesis, Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];
Pssm-ID: 440232 [Multi-domain] Cd Length: 397 Bit Score: 50.29 E-value: 4.18e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 979895810 438 LEAHHQVTFADDAFVAAAEFADRYITSRFLPDKAIDLIDQAAARVRIGATSRPVDIQEGEAQIAQLKREQDYATSRKRFD 517
Cdd:COG0464 2 AELLALAVALALALLLLDDAALRLLLLLLLALAAALLLLLLLLLLLLLALLLVELLLLLLSGALAALLLLALLLLALLAL 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 979895810 518 EAKQFEEQINAKQKSVDEMMEAWQRKTGSETLEVTVESVAEVVSRLTGIPVSELTQEERQKLLKME-----EQLRERVVG 592
Cdd:COG0464 82 LAALLSALELLLLGELLLLLLLLLLLLLLLLDLERALLELLRESAEALALAAPLVTYEDIGGLEEEllelrEAILDDLGG 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 979895810 593 QSDAVVAVSDAVRL--------SRAGLgqthRPIATFLFLGPTGVGKTELAKALAETVFGDeqaIIRIDMSEymerhava 664
Cdd:COG0464 162 LEEVKEELRELVALplkrpelrEEYGL----PPPRGLLLYGPPGTGKTLLARALAGELGLP---LIEVDLSD-------- 226
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 979895810 665 rLIGappGYVGydEGGQLTERV----RRRPYSVILLDEIEKAHPD-----------VYNVLLQVFDDGRltdgkgrvvdf 729
Cdd:COG0464 227 -LVS---KYVG--ETEKNLREVfdkaRGLAPCVLFIDEADALAGKrgevgdgvgrrVVNTLLTEMEELR----------- 289
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 979895810 730 SNTIIIATSNLgaaiiMDNLTqPEAARKTDKAI------REELMQVLKGHFRPeflNRIDEVIVFHALSKE----NIRSI 799
Cdd:COG0464 290 SDVVVIAATNR-----PDLLD-PALLRRFDEIIffplpdAEERLEIFRIHLRK---RPLDEDVDLEELAEAteglSGADI 360
|
410 420 430
....*....|....*....|....*....|.
gi 979895810 800 VQIqLDRVIRTAAAQDITLVMGDSLVEHLTE 830
Cdd:COG0464 361 RNV-VRRAALQALRLGREPVTTEDLLEALER 390
|
|
| RecA-like_HslU |
cd19498 |
ATP-dependent protease ATPase subunit HslU; HslU is a component of the ATP-dependent protease ... |
584-701 |
6.21e-06 |
|
ATP-dependent protease ATPase subunit HslU; HslU is a component of the ATP-dependent protease HslVU. In HslVU, HslU ATPase serves to unfold and translocate protein substrate, and the HslV protease degrades the unfolded proteins. This RecA-like_HslU subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.
Pssm-ID: 410906 [Multi-domain] Cd Length: 183 Bit Score: 47.76 E-value: 6.21e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 979895810 584 EQLRERVVGQSDAVVAVSDAV--RLSRAGLGQTHRPIAT---FLFLGPTGVGKTELAKALAETVfgdEQAIIRIDMSEYM 658
Cdd:cd19498 7 SELDKYIIGQDEAKRAVAIALrnRWRRMQLPEELRDEVTpknILMIGPTGVGKTEIARRLAKLA---GAPFIKVEATKFT 83
|
90 100 110 120
....*....|....*....|....*....|....*....|...
gi 979895810 659 ErhavarligapPGYVGYDeggqLTERVRRRPYSVILLDEIEK 701
Cdd:cd19498 84 E-----------VGYVGRD----VESIIRDLVEGIVFIDEIDK 111
|
|
| RPT1 |
COG1222 |
ATP-dependent 26S proteasome regulatory subunit [Posttranslational modification, protein ... |
590-848 |
1.09e-05 |
|
ATP-dependent 26S proteasome regulatory subunit [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 440835 [Multi-domain] Cd Length: 326 Bit Score: 48.46 E-value: 1.09e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 979895810 590 VVGQSDAVVAVSDAV--------RLSRAGLgqthRPIATFLFLGPTGVGKTELAKALAETVfgdEQAIIRIDMSEYMERh 661
Cdd:COG1222 80 IGGLDEQIEEIREAVelplknpeLFRKYGI----EPPKGVLLYGPPGTGKTLLAKAVAGEL---GAPFIRVRGSELVSK- 151
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 979895810 662 avarligappgYVGydEGGQLT----ERVRRRPYSVILLDEIE----KAHPD--------VYNVLLQVFDDgrlTDGKGR 725
Cdd:COG1222 152 -----------YIG--EGARNVrevfELAREKAPSIIFIDEIDaiaaRRTDDgtsgevqrTVNQLLAELDG---FESRGD 215
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 979895810 726 VvdfsntIIIATSNLGAAIimdnltqpeaarktDKAIReelmqvlkghfRPeflNRIDEVIVFHALSKENIRSIVQIQLd 805
Cdd:COG1222 216 V------LIIAATNRPDLL--------------DPALL-----------RP---GRFDRVIEVPLPDEEAREEILKIHL- 260
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|
gi 979895810 806 RVIRTAAAQDITLVM-------GDSLVEHLTEAGYqpeFGARELKRQIRQ 848
Cdd:COG1222 261 RDMPLADDVDLDKLAkltegfsGADLKAIVTEAGM---FAIREGRDTVTM 307
|
|
| COG1223 |
COG1223 |
Predicted ATPase, AAA+ superfamily [General function prediction only]; |
283-432 |
2.90e-05 |
|
Predicted ATPase, AAA+ superfamily [General function prediction only];
Pssm-ID: 440836 [Multi-domain] Cd Length: 246 Bit Score: 46.42 E-value: 2.90e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 979895810 283 LIGEPGVGKTAIVEGLAQRIvngdvpevlrDKRLVEVNINSMVAgaKYRGEFEERAKQLIDEvtAKQDELILFIDELHTI 362
Cdd:COG1223 40 FYGPPGTGKTMLAEALAGEL----------KLPLLTVRLDSLIG--SYLGETARNLRKLFDF--ARRAPCVIFFDEFDAI 105
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 979895810 363 VGAGQGGGEGGlDIANVLKPALA-----RGELSLIGATTLNEyqkyiEKDAALERRFQPVF-VPEPSVEQTIVILR 432
Cdd:COG1223 106 AKDRGDQNDVG-EVKRVVNALLQeldglPSGSVVIAATNHPE-----LLDSALWRRFDEVIeFPLPDKEERKEILE 175
|
|
| SpoVK |
COG0464 |
AAA+-type ATPase, SpoVK/Ycf46/Vps4 family [Cell wall/membrane/envelope biogenesis, Cell cycle ... |
282-432 |
1.42e-04 |
|
AAA+-type ATPase, SpoVK/Ycf46/Vps4 family [Cell wall/membrane/envelope biogenesis, Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];
Pssm-ID: 440232 [Multi-domain] Cd Length: 397 Bit Score: 45.29 E-value: 1.42e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 979895810 282 VLIGEPGVGKTAIVEGLAQRIvngdvpevlrDKRLVEVNINSMVagAKYRGEFEERAKQLIDEvtAKQDEL-ILFIDELH 360
Cdd:COG0464 195 LLYGPPGTGKTLLARALAGEL----------GLPLIEVDLSDLV--SKYVGETEKNLREVFDK--ARGLAPcVLFIDEAD 260
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 979895810 361 TIVGAGQGGGEGGLDIA-NVLKPALA--RGELSLIGATtlNeyqkYIEK-DAALERRFQ-PVFVPEPSVEQTIVILR 432
Cdd:COG0464 261 ALAGKRGEVGDGVGRRVvNTLLTEMEelRSDVVVIAAT--N----RPDLlDPALLRRFDeIIFFPLPDAEERLEIFR 331
|
|
| PRK13341 |
PRK13341 |
AAA family ATPase; |
280-400 |
1.74e-04 |
|
AAA family ATPase;
Pssm-ID: 237354 [Multi-domain] Cd Length: 725 Bit Score: 45.43 E-value: 1.74e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 979895810 280 NPVLIGEPGVGKTAivegLAQRIVNGDVPEVlrdkrlveVNINSMVAGAKYRGEFEERAKQLIDEVTAKqdeLILFIDEL 359
Cdd:PRK13341 54 SLILYGPPGVGKTT----LARIIANHTRAHF--------SSLNAVLAGVKDLRAEVDRAKERLERHGKR---TILFIDEV 118
|
90 100 110 120
....*....|....*....|....*....|....*....|...
gi 979895810 360 HtivgagqgggegGLDIA--NVLKPALARGELSLIGATTLNEY 400
Cdd:PRK13341 119 H------------RFNKAqqDALLPWVENGTITLIGATTENPY 149
|
|
| DNA_pol3_delta2 |
pfam13177 |
DNA polymerase III, delta subunit; DNA polymerase III, delta subunit (EC 2.7.7.7) is required ... |
621-711 |
1.09e-03 |
|
DNA polymerase III, delta subunit; DNA polymerase III, delta subunit (EC 2.7.7.7) is required for, along with delta' subunit, the assembly of the processivity factor beta(2) onto primed DNA in the DNA polymerase III holoenzyme-catalyzed reaction. The delta subunit is also known as HolA.
Pssm-ID: 433013 [Multi-domain] Cd Length: 161 Bit Score: 40.66 E-value: 1.09e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 979895810 621 FLFLGPTGVGKTELAKALAETVFGDEQAIiridmSEYMERHAVARLI--GAPPGYVGYDEGGQ---------LTERVRRR 689
Cdd:pfam13177 22 YLFSGPEGVGKLELALAFAKALFCEEPGD-----DLPCGQCRSCRRIesGNHPDLVIIEPEGQsikidqireLQKEFSKS 96
|
90 100
....*....|....*....|....*.
gi 979895810 690 PY----SVILLDEIEKAHPDVYNVLL 711
Cdd:pfam13177 97 PYegkkKVYIIEDAEKMTASAANSLL 122
|
|
| Clp_N |
pfam02861 |
Clp amino terminal domain, pathogenicity island component; This short domain is found in one ... |
95-143 |
2.40e-03 |
|
Clp amino terminal domain, pathogenicity island component; This short domain is found in one or two copies at the amino terminus of ClpA and ClpB proteins from bacteria and eukaryotes. The function of these domains is uncertain but they may form a protein binding site. In many bacterial species, including E.coli, this region represents the N-terminus of one of the key components of the pathogenicity island complex that injects toxin from one bacterium into another.
Pssm-ID: 460724 [Multi-domain] Cd Length: 53 Bit Score: 36.73 E-value: 2.40e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|.
gi 979895810 95 AAEKAHELRRSELDSEHLLYALADTD--VCAALLKELKLSPQDIRSYIDEH 143
Cdd:pfam02861 1 AQELARALGHQYIGTEHLLLALLEEDdgLAARLLKKAGVDLDALREAIEKL 51
|
|
| DnaX |
COG2812 |
DNA polymerase III, gamma/tau subunits [Replication, recombination and repair]; |
588-639 |
2.42e-03 |
|
DNA polymerase III, gamma/tau subunits [Replication, recombination and repair];
Pssm-ID: 442061 [Multi-domain] Cd Length: 340 Bit Score: 41.33 E-value: 2.42e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|...
gi 979895810 588 ERVVGQSDAVVAVSDAVRLSRaglgqthrpIA-TFLFLGPTGVGKTELAKALA 639
Cdd:COG2812 10 DDVVGQEHVVRTLKNALASGR---------LAhAYLFTGPRGVGKTTLARILA 53
|
|
| RecA-like_protease |
cd19481 |
proteases similar to RecA; RecA-like NTPases. This family includes the NTP binding domain of ... |
283-362 |
6.23e-03 |
|
proteases similar to RecA; RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.
Pssm-ID: 410889 [Multi-domain] Cd Length: 158 Bit Score: 38.42 E-value: 6.23e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 979895810 283 LIGEPGVGKTAIVEGLAQRIvngDVPevlrdkrLVEVNINSMVagAKYRGEFEERAKQLIDEVTAKQDeLILFIDELHTI 362
Cdd:cd19481 31 LYGPPGTGKTLLAKALAGEL---GLP-------LIVVKLSSLL--SKYVGESEKNLRKIFERARRLAP-CILFIDEIDAI 97
|
|
| COG3899 |
COG3899 |
Predicted ATPase [General function prediction only]; |
7-303 |
8.47e-03 |
|
Predicted ATPase [General function prediction only];
Pssm-ID: 443106 [Multi-domain] Cd Length: 1244 Bit Score: 40.23 E-value: 8.47e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 979895810 7 ICHARPAVARATVMQDGERKTISICDYHFRQLMRHQSMLNPFDSLLGGGSSSLFGGLGDESPLAAEVPRESVDPTDAFSE 86
Cdd:COG3899 24 AALALLAAALLLLLLLALRLALLLLALALLLLLLLALLLLLALLLALLLLALLLLALALLRLLAAERLALLLALALALLA 103
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 979895810 87 QTLELLQRAAEKAHELRRSELDSEHLLYALADTDVCAALLKELKLSPQDIRSYIDEHAHTGTADPDAPLDKLSISPRVKK 166
Cdd:COG3899 104 ALLLLLALALLLLALLALALLALLLALLLAAGVLGLLLGGLLLAALAALLALAALAAAAAAAAAAAAARAARLRRARAAR 183
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 979895810 167 AVQYAFQASRDLGHSYIGPEHLLIGLASVPDSVAGTLLKKYGVTPEALRQKVVKVVGKGAED-------------GRVDA 233
Cdd:COG3899 184 LAALALRALLLLVLLLLLLLLLLGLLLAAAAALAAAAAAAAAAAPAAPVVLVAALLLALAALlallllaarllglAGAAA 263
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 979895810 234 PTGTPNLDKFGRDLTAIARQGKLDPVLGRAQEIESTIEVL--ARRKKNNPVLI-GEPGVGKTAIVEGLAQRIV 303
Cdd:COG3899 264 LLLLGLLAAAAAGRRLLARRLIPQPLVGREAELAALLAALerARAGRGELVLVsGEAGIGKSRLVRELARRAR 336
|
|
| |
