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Conserved domains on  [gi|973692854|gb|ALX39975|]
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pleiomorphic adenoma protein-like 2, partial [Hemiculter sp. 'Hainan']

Protein Classification

zinc finger family protein( domain architecture ID 706824)

zinc finger family protein may be involved in transcriptional regulation; similar to Schizosaccharomyces pombe E3 ubiquitin-protein ligase hel2, which that plays a key role in the ribosome quality control (RQC), and Homo sapiens histone H4 transcription factor

Gene Ontology:  GO:0008270
PubMed:  11179890

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
COG5236 super family cl28715
Uncharacterized conserved protein, contains RING Zn-finger [General function prediction only];
7-133 3.55e-04

Uncharacterized conserved protein, contains RING Zn-finger [General function prediction only];


The actual alignment was detected with superfamily member COG5236:

Pssm-ID: 227561 [Multi-domain]  Cd Length: 493  Bit Score: 41.54  E-value: 3.55e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973692854   7 HLQTHDPNKEAFKCEECGKHYNTKlGYKRHMAMHSATAGDLTCKVCLQSYESTPALLE-----HLKSHSGKSSGGAKEKK 81
Cdd:COG5236  141 DVRDEMEDLLSFKCPKSKCHRRCG-SLKELKKHYKAQHGFVLCSECIGNKKDFWNEIRlfrssTLRDHKNGGLEEEGFKG 219

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 973692854  82 HP-CDHCDRRFYTRKDVRRHMVVHTGRkdflCQYC-------AQRFGRKDHLTRHVKKSH 133
Cdd:COG5236  220 HPlCIFCKIYFYDDDELRRHCRLRHEA----CHICdmvgpirYQYFKSYEDLEAHFRNAH 275
 
Name Accession Description Interval E-value
COG5236 COG5236
Uncharacterized conserved protein, contains RING Zn-finger [General function prediction only];
7-133 3.55e-04

Uncharacterized conserved protein, contains RING Zn-finger [General function prediction only];


Pssm-ID: 227561 [Multi-domain]  Cd Length: 493  Bit Score: 41.54  E-value: 3.55e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973692854   7 HLQTHDPNKEAFKCEECGKHYNTKlGYKRHMAMHSATAGDLTCKVCLQSYESTPALLE-----HLKSHSGKSSGGAKEKK 81
Cdd:COG5236  141 DVRDEMEDLLSFKCPKSKCHRRCG-SLKELKKHYKAQHGFVLCSECIGNKKDFWNEIRlfrssTLRDHKNGGLEEEGFKG 219

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 973692854  82 HP-CDHCDRRFYTRKDVRRHMVVHTGRkdflCQYC-------AQRFGRKDHLTRHVKKSH 133
Cdd:COG5236  220 HPlCIFCKIYFYDDDELRRHCRLRHEA----CHICdmvgpirYQYFKSYEDLEAHFRNAH 275
 
Name Accession Description Interval E-value
COG5236 COG5236
Uncharacterized conserved protein, contains RING Zn-finger [General function prediction only];
7-133 3.55e-04

Uncharacterized conserved protein, contains RING Zn-finger [General function prediction only];


Pssm-ID: 227561 [Multi-domain]  Cd Length: 493  Bit Score: 41.54  E-value: 3.55e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973692854   7 HLQTHDPNKEAFKCEECGKHYNTKlGYKRHMAMHSATAGDLTCKVCLQSYESTPALLE-----HLKSHSGKSSGGAKEKK 81
Cdd:COG5236  141 DVRDEMEDLLSFKCPKSKCHRRCG-SLKELKKHYKAQHGFVLCSECIGNKKDFWNEIRlfrssTLRDHKNGGLEEEGFKG 219

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 973692854  82 HP-CDHCDRRFYTRKDVRRHMVVHTGRkdflCQYC-------AQRFGRKDHLTRHVKKSH 133
Cdd:COG5236  220 HPlCIFCKIYFYDDDELRRHCRLRHEA----CHICdmvgpirYQYFKSYEDLEAHFRNAH 275
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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