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Conserved domains on  [gi|973165475|gb|KUL05248|]
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Aspartate carbamoyltransferase [Methanomicrobiales archaeon 53_19]

Protein Classification

aspartate carbamoyltransferase( domain architecture ID 11489502)

aspartate carbamoyltransferase catalyzes the conversion of aspartate and carbamoyl phosphate to carbamoyl-L-aspartate, the first unique step of pyrimidine biosynthesis

CATH:  3.40.50.1370
EC:  2.1.3.2
Gene Ontology:  GO:0004070|GO:0006520|GO:0016597|GO:0016743
SCOP:  4000794

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
asp_carb_tr TIGR00670
aspartate carbamoyltransferase; Aspartate transcarbamylase (ATCase) is an alternate name.PyrB ...
 2-297 3.99e-147

aspartate carbamoyltransferase; Aspartate transcarbamylase (ATCase) is an alternate name.PyrB encodes the catalytic chain of aspartate carbamoyltransferase, an enzyme of pyrimidine biosynthesis, which organizes into trimers. In some species, including E. coli and the Archaea but excluding Bacillus subtilis, a regulatory subunit PyrI is also present in an allosterically regulated hexameric holoenzyme. Several molecular weight classes of ATCase are described in MEDLINE:96303527 and often vary within taxa. PyrB and PyrI are fused in Thermotoga maritima.Ornithine carbamoyltransferases are in the same superfamily and form an outgroup. [Purines, pyrimidines, nucleosides, and nucleotides, Pyrimidine ribonucleotide biosynthesis]


:

Pssm-ID: 273209 [Multi-domain]  Cd Length: 301  Bit Score: 414.83  E-value: 3.99e-147
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973165475    2 RHIISINEVSTEEIDDILDRASAIEEGAYD---PDLLNGKILANLFFEPSTRTQMSFVSAMFRLGGKVINLGSIEASSIA 78
Cdd:TIGR00670   1 RHLISISDLSREEIELLLETARELEQVLNGkepLKLLKGKILANLFFEPSTRTRLSFETAMKRLGGSVVNFSDSETSSVA 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973165475   79 KGETLADTIRVVSGYADAIVLRHPKEGAARLASEFSDVPVINAGDGAGQHPSQTLLDLFTIRQSF-PLNGINVGFLGDLR 157
Cdd:TIGR00670  81 KGETLADTIKTLSGYVDAIVIRHPLEGAARLAAEVSEVPVINAGDGSNQHPTQTLLDLYTIYEEFgRLDGLKIALVGDLK 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973165475  158 YGRTAHSLATALSRYGVIIHTITPPGLELPPSLTHDLLDTGTKIVVHEHLEDIIADLDVLYVTRIQRERFPDPGAYASVA 237
Cdd:TIGR00670 161 YGRTVHSLAEALTRFGVEVYLISPEELRMPKEILEELKAKGIKVRETESLEEVIDEADVLYVTRIQKERFPDPEEYEKVK 240

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 973165475  238 SGYRVTPEMLADVSDRFILMHPLPRVDEIDPQVDSMPCARYFEQARNGVPIRMAMLQKVL 297
Cdd:TIGR00670 241 GSYGITLERLEAAKKGVIIMHPLPRVDEIDPSVDDTPHAKYFKQAFNGVPVRMALLALLL 300
 
Name Accession Description Interval E-value
asp_carb_tr TIGR00670
aspartate carbamoyltransferase; Aspartate transcarbamylase (ATCase) is an alternate name.PyrB ...
 2-297 3.99e-147

aspartate carbamoyltransferase; Aspartate transcarbamylase (ATCase) is an alternate name.PyrB encodes the catalytic chain of aspartate carbamoyltransferase, an enzyme of pyrimidine biosynthesis, which organizes into trimers. In some species, including E. coli and the Archaea but excluding Bacillus subtilis, a regulatory subunit PyrI is also present in an allosterically regulated hexameric holoenzyme. Several molecular weight classes of ATCase are described in MEDLINE:96303527 and often vary within taxa. PyrB and PyrI are fused in Thermotoga maritima.Ornithine carbamoyltransferases are in the same superfamily and form an outgroup. [Purines, pyrimidines, nucleosides, and nucleotides, Pyrimidine ribonucleotide biosynthesis]


Pssm-ID: 273209 [Multi-domain]  Cd Length: 301  Bit Score: 414.83  E-value: 3.99e-147
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973165475    2 RHIISINEVSTEEIDDILDRASAIEEGAYD---PDLLNGKILANLFFEPSTRTQMSFVSAMFRLGGKVINLGSIEASSIA 78
Cdd:TIGR00670   1 RHLISISDLSREEIELLLETARELEQVLNGkepLKLLKGKILANLFFEPSTRTRLSFETAMKRLGGSVVNFSDSETSSVA 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973165475   79 KGETLADTIRVVSGYADAIVLRHPKEGAARLASEFSDVPVINAGDGAGQHPSQTLLDLFTIRQSF-PLNGINVGFLGDLR 157
Cdd:TIGR00670  81 KGETLADTIKTLSGYVDAIVIRHPLEGAARLAAEVSEVPVINAGDGSNQHPTQTLLDLYTIYEEFgRLDGLKIALVGDLK 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973165475  158 YGRTAHSLATALSRYGVIIHTITPPGLELPPSLTHDLLDTGTKIVVHEHLEDIIADLDVLYVTRIQRERFPDPGAYASVA 237
Cdd:TIGR00670 161 YGRTVHSLAEALTRFGVEVYLISPEELRMPKEILEELKAKGIKVRETESLEEVIDEADVLYVTRIQKERFPDPEEYEKVK 240

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 973165475  238 SGYRVTPEMLADVSDRFILMHPLPRVDEIDPQVDSMPCARYFEQARNGVPIRMAMLQKVL 297
Cdd:TIGR00670 241 GSYGITLERLEAAKKGVIIMHPLPRVDEIDPSVDDTPHAKYFKQAFNGVPVRMALLALLL 300
PyrB COG0540
Aspartate carbamoyltransferase, catalytic subunit [Nucleotide transport and metabolism]; ...
 1-297 4.09e-147

Aspartate carbamoyltransferase, catalytic subunit [Nucleotide transport and metabolism]; Aspartate carbamoyltransferase, catalytic subunit is part of the Pathway/BioSystem: Pyrimidine biosynthesis


Pssm-ID: 440306 [Multi-domain]  Cd Length: 306  Bit Score: 414.84  E-value: 4.09e-147
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973165475   1 MRHIISINEVSTEEIDDILDRASAIEEGAYD---PDLLNGKILANLFFEPSTRTQMSFVSAMFRLGGKVINLgSIEASSI 77
Cdd:COG0540    5 MRHLLSIEDLSREEIEELLDTAEEFKEVLRPikkVPLLRGKTVANLFFEPSTRTRLSFELAAKRLGADVINF-SASTSSV 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973165475  78 AKGETLADTIRVVSGY-ADAIVLRHPKEGAARLASEFSDVPVINAGDGAGQHPSQTLLDLFTIRQSFP-LNGINVGFLGD 155
Cdd:COG0540   84 SKGESLADTIRTLEAYgADAIVIRHPQEGAARLLAEHVDVPVINAGDGAHEHPTQALLDLYTIREEFGrLDGLKVAIVGD 163

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973165475 156 LRYGRTAHSLATALSRYGVIIHTITPPglELPPSLTHDLldtgtKIVVHEHLEDIIADLDVLYVTRIQRERFPDP--GAY 233
Cdd:COG0540  164 LKHSRVARSNIKALSKLGAEVTLVAPP--TLLPEEIEEL-----GVEVTTDLDEALPDADVVYMLRIQKERFTDGlfPSY 236

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 973165475 234 ASVASGYRVTPEMLADVSDRFILMHPLP--RVDEIDPQVDSMPCARYFEQARNGVPIRMAMLQKVL 297
Cdd:COG0540  237 REYKRSYGLTAERLALAKPDAIVMHPGPrnRGVEIDSDVDDTPRSVIFEQVTNGVAVRMALLYLLL 302
pyrB PRK00856
aspartate carbamoyltransferase catalytic subunit;
1-297 2.14e-142

aspartate carbamoyltransferase catalytic subunit;


Pssm-ID: 234849 [Multi-domain]  Cd Length: 305  Bit Score: 402.91  E-value: 2.14e-142
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973165475   1 MRHIISINEVSTEEIDDILDRASAIEEGAYDP----DLLNGKILANLFFEPSTRTQMSFVSAMFRLGGKVINLgSIEASS 76
Cdd:PRK00856   5 MKHLLSIEDLSREEIELLLDTAEEFKEVLRREvkkvPLLRGKTVANLFFEPSTRTRLSFELAAKRLGADVINF-SASTSS 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973165475  77 IAKGETLADTIRVVSGY-ADAIVLRHPKEGAARLASEFSDVPVINAGDGAGQHPSQTLLDLFTIRQSF-PLNGINVGFLG 154
Cdd:PRK00856  84 VSKGETLADTIRTLSAMgADAIVIRHPQSGAARLLAESSDVPVINAGDGSHQHPTQALLDLLTIREEFgRLEGLKVAIVG 163

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973165475 155 DLRYGRTAHSLATALSRYGVIIHTITPPGLeLPPSLthdlldtgTKIVVHEHLEDIIADLDVLYVTRIQRERFPDPG--A 232
Cdd:PRK00856 164 DIKHSRVARSNIQALTRLGAEVRLIAPPTL-LPEGM--------PEYGVHTDLDEVIEDADVVMMLRVQKERMDGGLlpS 234

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 973165475 233 YASVASGYRVTPEMLADVSDRFILMHPLP--RVDEIDPQVDSMPCARYFEQARNGVPIRMAMLQKVL 297
Cdd:PRK00856 235 YEEYKRSYGLTAERLALAKPDAIVMHPGPvnRGVEIASDVADGPQSVIFEQVTNGVAVRMAVLELLL 301
OTCace_N pfam02729
Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain;
3-141 2.43e-60

Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain;


Pssm-ID: 460665 [Multi-domain]  Cd Length: 140  Bit Score: 188.41  E-value: 2.43e-60
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973165475    3 HIISINEVSTEEIDDILDRASAIEEGAYD---PDLLNGKILANLFFEPSTRTQMSFVSAMFRLGGKVINLGSiEASSIAK 79
Cdd:pfam02729   1 HFLSLEDLSREEIEALLDLAAELKEARKRgkkLPLLKGKTVALLFEEPSTRTRVSFEVAAKRLGGHVIYLSS-SDIQLSS 79

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 973165475   80 GETLADTIRVVSGYADAIVLRHPKEGAARLASEFSDVPVINAGdGAGQHPSQTLLDLFTIRQ 141
Cdd:pfam02729  80 GESLADTARVLSRYVDAIVIRHFGHEDLEELAEYASVPVINAG-GDHEHPTQALADLLTIRE 140
 
Name Accession Description Interval E-value
asp_carb_tr TIGR00670
aspartate carbamoyltransferase; Aspartate transcarbamylase (ATCase) is an alternate name.PyrB ...
 2-297 3.99e-147

aspartate carbamoyltransferase; Aspartate transcarbamylase (ATCase) is an alternate name.PyrB encodes the catalytic chain of aspartate carbamoyltransferase, an enzyme of pyrimidine biosynthesis, which organizes into trimers. In some species, including E. coli and the Archaea but excluding Bacillus subtilis, a regulatory subunit PyrI is also present in an allosterically regulated hexameric holoenzyme. Several molecular weight classes of ATCase are described in MEDLINE:96303527 and often vary within taxa. PyrB and PyrI are fused in Thermotoga maritima.Ornithine carbamoyltransferases are in the same superfamily and form an outgroup. [Purines, pyrimidines, nucleosides, and nucleotides, Pyrimidine ribonucleotide biosynthesis]


Pssm-ID: 273209 [Multi-domain]  Cd Length: 301  Bit Score: 414.83  E-value: 3.99e-147
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973165475    2 RHIISINEVSTEEIDDILDRASAIEEGAYD---PDLLNGKILANLFFEPSTRTQMSFVSAMFRLGGKVINLGSIEASSIA 78
Cdd:TIGR00670   1 RHLISISDLSREEIELLLETARELEQVLNGkepLKLLKGKILANLFFEPSTRTRLSFETAMKRLGGSVVNFSDSETSSVA 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973165475   79 KGETLADTIRVVSGYADAIVLRHPKEGAARLASEFSDVPVINAGDGAGQHPSQTLLDLFTIRQSF-PLNGINVGFLGDLR 157
Cdd:TIGR00670  81 KGETLADTIKTLSGYVDAIVIRHPLEGAARLAAEVSEVPVINAGDGSNQHPTQTLLDLYTIYEEFgRLDGLKIALVGDLK 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973165475  158 YGRTAHSLATALSRYGVIIHTITPPGLELPPSLTHDLLDTGTKIVVHEHLEDIIADLDVLYVTRIQRERFPDPGAYASVA 237
Cdd:TIGR00670 161 YGRTVHSLAEALTRFGVEVYLISPEELRMPKEILEELKAKGIKVRETESLEEVIDEADVLYVTRIQKERFPDPEEYEKVK 240

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 973165475  238 SGYRVTPEMLADVSDRFILMHPLPRVDEIDPQVDSMPCARYFEQARNGVPIRMAMLQKVL 297
Cdd:TIGR00670 241 GSYGITLERLEAAKKGVIIMHPLPRVDEIDPSVDDTPHAKYFKQAFNGVPVRMALLALLL 300
PyrB COG0540
Aspartate carbamoyltransferase, catalytic subunit [Nucleotide transport and metabolism]; ...
 1-297 4.09e-147

Aspartate carbamoyltransferase, catalytic subunit [Nucleotide transport and metabolism]; Aspartate carbamoyltransferase, catalytic subunit is part of the Pathway/BioSystem: Pyrimidine biosynthesis


Pssm-ID: 440306 [Multi-domain]  Cd Length: 306  Bit Score: 414.84  E-value: 4.09e-147
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973165475   1 MRHIISINEVSTEEIDDILDRASAIEEGAYD---PDLLNGKILANLFFEPSTRTQMSFVSAMFRLGGKVINLgSIEASSI 77
Cdd:COG0540    5 MRHLLSIEDLSREEIEELLDTAEEFKEVLRPikkVPLLRGKTVANLFFEPSTRTRLSFELAAKRLGADVINF-SASTSSV 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973165475  78 AKGETLADTIRVVSGY-ADAIVLRHPKEGAARLASEFSDVPVINAGDGAGQHPSQTLLDLFTIRQSFP-LNGINVGFLGD 155
Cdd:COG0540   84 SKGESLADTIRTLEAYgADAIVIRHPQEGAARLLAEHVDVPVINAGDGAHEHPTQALLDLYTIREEFGrLDGLKVAIVGD 163

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973165475 156 LRYGRTAHSLATALSRYGVIIHTITPPglELPPSLTHDLldtgtKIVVHEHLEDIIADLDVLYVTRIQRERFPDP--GAY 233
Cdd:COG0540  164 LKHSRVARSNIKALSKLGAEVTLVAPP--TLLPEEIEEL-----GVEVTTDLDEALPDADVVYMLRIQKERFTDGlfPSY 236

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 973165475 234 ASVASGYRVTPEMLADVSDRFILMHPLP--RVDEIDPQVDSMPCARYFEQARNGVPIRMAMLQKVL 297
Cdd:COG0540  237 REYKRSYGLTAERLALAKPDAIVMHPGPrnRGVEIDSDVDDTPRSVIFEQVTNGVAVRMALLYLLL 302
pyrB PRK00856
aspartate carbamoyltransferase catalytic subunit;
1-297 2.14e-142

aspartate carbamoyltransferase catalytic subunit;


Pssm-ID: 234849 [Multi-domain]  Cd Length: 305  Bit Score: 402.91  E-value: 2.14e-142
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973165475   1 MRHIISINEVSTEEIDDILDRASAIEEGAYDP----DLLNGKILANLFFEPSTRTQMSFVSAMFRLGGKVINLgSIEASS 76
Cdd:PRK00856   5 MKHLLSIEDLSREEIELLLDTAEEFKEVLRREvkkvPLLRGKTVANLFFEPSTRTRLSFELAAKRLGADVINF-SASTSS 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973165475  77 IAKGETLADTIRVVSGY-ADAIVLRHPKEGAARLASEFSDVPVINAGDGAGQHPSQTLLDLFTIRQSF-PLNGINVGFLG 154
Cdd:PRK00856  84 VSKGETLADTIRTLSAMgADAIVIRHPQSGAARLLAESSDVPVINAGDGSHQHPTQALLDLLTIREEFgRLEGLKVAIVG 163

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973165475 155 DLRYGRTAHSLATALSRYGVIIHTITPPGLeLPPSLthdlldtgTKIVVHEHLEDIIADLDVLYVTRIQRERFPDPG--A 232
Cdd:PRK00856 164 DIKHSRVARSNIQALTRLGAEVRLIAPPTL-LPEGM--------PEYGVHTDLDEVIEDADVVMMLRVQKERMDGGLlpS 234

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 973165475 233 YASVASGYRVTPEMLADVSDRFILMHPLP--RVDEIDPQVDSMPCARYFEQARNGVPIRMAMLQKVL 297
Cdd:PRK00856 235 YEEYKRSYGLTAERLALAKPDAIVMHPGPvnRGVEIASDVADGPQSVIFEQVTNGVAVRMAVLELLL 301
PLN02527 PLN02527
aspartate carbamoyltransferase
 13-298 1.73e-99

aspartate carbamoyltransferase


Pssm-ID: 178142 [Multi-domain]  Cd Length: 306  Bit Score: 294.35  E-value: 1.73e-99
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973165475  13 EEIDDILDRASAIEEGAYDPDLLNGKILANLFFEPSTRTQMSFVSAMFRLGGKVINL-GSIEASSIAKGETLADTIRVVS 91
Cdd:PLN02527  15 ELLFEVAREMEKVERGSPGSQMLKGYLMATLFYEPSTRTRLSFESAMKRLGGEVLTTeNAGEFSSAAKGETLEDTIRTVE 94

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973165475  92 GYADAIVLRHPKEGAARLASEFSDVPVINAGDGAGQHPSQTLLDLFTI-RQSFPLNGINVGFLGDLRYGRTAHSLATALS 170
Cdd:PLN02527  95 GYSDIIVLRHFESGAARRAAATAEIPVINAGDGPGQHPTQALLDVYTIqREIGRLDGIKVGLVGDLANGRTVRSLAYLLA 174

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973165475 171 RY-GVIIHTITPPGLELPPSLTHDLLDTGTKIVVHEHLEDIIADLDVLYVTRIQRERFPDP-GAYASVASGYRVTPEMLA 248
Cdd:PLN02527 175 KYeDVKIYFVAPDVVKMKDDIKDYLTSKGVEWEESSDLMEVASKCDVLYQTRIQRERFGERiDLYEAARGKYIVDKKVMD 254

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|
gi 973165475 249 DVSDRFILMHPLPRVDEIDPQVDSMPCARYFEQARNGVPIRMAMLQKVLV 298
Cdd:PLN02527 255 VLPKHAVVMHPLPRLDEITTDVDSDPRAAYFRQAKNGLFIRMALLKLLLG 304
PRK08192 PRK08192
aspartate carbamoyltransferase; Provisional
 3-297 1.90e-83

aspartate carbamoyltransferase; Provisional


Pssm-ID: 169269 [Multi-domain]  Cd Length: 338  Bit Score: 254.65  E-value: 1.90e-83
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973165475   3 HIISINEVSTEEIDDILDRASAIEEGAYDP---DLLNGKILANLFFEPSTRTQMSFVSAMFRLGGKVINLGSIEASSIAK 79
Cdd:PRK08192   7 HILSVNQLDRDAIQRIFNVADRMEPYALREkrtRVLEGAILGNLFFEPSTRTRVSFGCAFNLLGGHVRETTGMASSSLSK 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973165475  80 GETLADTIRVVSGYADAIVLRHPKEGAARLASEFSDVPVINAGDGAGQHPSQTLLDLFTIRQSFP-----LNGINVGFLG 154
Cdd:PRK08192  87 GESLYDTARVLSTYSDVIAMRHPDAGSVKEFAEGSRVPVINGGDGSNEHPTQALLDLFTIQKELAhagrgIDGMHIAMVG 166

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973165475 155 DLRYGRTAHSLATALSRYGVIIHT-ITPPGLELPPSLTHDLLDTGTKIVVHEHLEDIIADLDVLYVTRIQRERFPDPgay 233
Cdd:PRK08192 167 DLKFGRTVHSLSRLLCMYKNVSFTlVSPKELAMPDYVISDIENAGHKITITDQLEGNLDKADILYLTRIQEERFPSQ--- 243

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 973165475 234 aSVASGYRVTPEMLADVSDRF-----ILMHPLPR-----VDEIDPQVDSMPCARYFEQARNGVPIRMAMLQKVL 297
Cdd:PRK08192 244 -EEANKYRGKFRLNQSIYTQHcksntVIMHPLPRdsraqANELDNDLNSHPNLAIFRQADNGLLIRMALFALTL 316
PRK11891 PRK11891
aspartate carbamoyltransferase; Provisional
 3-297 1.73e-76

aspartate carbamoyltransferase; Provisional


Pssm-ID: 183362 [Multi-domain]  Cd Length: 429  Bit Score: 239.77  E-value: 1.73e-76
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973165475   3 HIISINEVSTEEIDDIL---DRASAIEEGAYDPDLLNGKILANLFFEPSTRTQMSFVSAMFRLGGKVINLGSIEASSIAK 79
Cdd:PRK11891  89 QLLSVDQFSRDSVEALFrvaDVMQPIARRQKISRVLEGAVLGNLFFEASTRTRVSFGAAFCRLGGSVCDTTGFTFSSMAK 168

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973165475  80 GETLADTIRVVSGYADAIVLRHPKEGAARLASEFSDVPVINAGDGAGQHPSQTLLDLFTIRQSFP-----LNGINVGFLG 154
Cdd:PRK11891 169 GESIYDTSRVMSGYVDALVIRHPEQGSVAEFARATNLPVINGGDGPGEHPSQALLDLYTIQREFSrlgkiVDGAHIALVG 248

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973165475 155 DLRYGRTAHSLATALSRY-GVIIHTITPPGLELPPSLTHDLLDTGTKIVVHEHLEDIIADLDVLYVTRIQRERFPDpGAY 233
Cdd:PRK11891 249 DLKYGRTVHSLVKLLALYrGLKFTLVSPPTLEMPAYIVEQISRNGHVIEQTDDLAAGLRGADVVYATRIQKERFAD-ESF 327

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973165475 234 ASVASGYRVTPEMLADVSDR-FILMHPLPR-----VDEIDPQVDSMPCARYFEQARNGVPIRMAMLQKVL 297
Cdd:PRK11891 328 EGYTPDFQINQALVDAVCKPdTLIMHPLPRdsrpgANDLSTDLNRDPRLAIFRQTDNGIPVRMAIFAVLL 397
OTCace_N pfam02729
Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain;
3-141 2.43e-60

Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain;


Pssm-ID: 460665 [Multi-domain]  Cd Length: 140  Bit Score: 188.41  E-value: 2.43e-60
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973165475    3 HIISINEVSTEEIDDILDRASAIEEGAYD---PDLLNGKILANLFFEPSTRTQMSFVSAMFRLGGKVINLGSiEASSIAK 79
Cdd:pfam02729   1 HFLSLEDLSREEIEALLDLAAELKEARKRgkkLPLLKGKTVALLFEEPSTRTRVSFEVAAKRLGGHVIYLSS-SDIQLSS 79

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 973165475   80 GETLADTIRVVSGYADAIVLRHPKEGAARLASEFSDVPVINAGdGAGQHPSQTLLDLFTIRQ 141
Cdd:pfam02729  80 GESLADTARVLSRYVDAIVIRHFGHEDLEELAEYASVPVINAG-GDHEHPTQALADLLTIRE 140
ArgF COG0078
Ornithine carbamoyltransferase [Amino acid transport and metabolism]; Ornithine ...
 1-293 2.32e-57

Ornithine carbamoyltransferase [Amino acid transport and metabolism]; Ornithine carbamoyltransferase is part of the Pathway/BioSystem: Arginine biosynthesis


Pssm-ID: 439848 [Multi-domain]  Cd Length: 310  Bit Score: 186.80  E-value: 2.32e-57
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973165475   1 MRHIISINEVSTEEIDDILDRASAIEEGAY---DPDLLNGKILANLFFEPSTRTQMSFVSAMFRLGGKVINLGSiEASSI 77
Cdd:COG0078    5 GRHFLSLLDLTPEELRALLDLAAELKAKRKagiPHRPLKGKTLAMIFEKPSTRTRVSFEVGMAQLGGHAIYLDP-GDSQL 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973165475  78 AKGETLADTIRVVSGYADAIVLR---HpkEGAARLAsEFSDVPVINagdgaGQ----HPSQTLLDLFTIRQSF-PLNGIN 149
Cdd:COG0078   84 GRGESIKDTARVLSRYVDGIMIRtfgH--ETLEELA-KYAGVPVIN-----GLtdlfHPCQALADLLTIREHFgKLKGLK 155

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973165475 150 VGFLGDlryGR-TAHSLATALSRYGVIIHTITPPGLELPPslthDLLD--------TGTKIVVHEHLEDIIADLDVLYvT 220
Cdd:COG0078  156 VAYVGD---GNnVANSLLLAAAKLGMDVRIATPEGYEPDP----EIVAkakeiaaeSGGSITITHDPAEAVKGADVVY-T 227

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973165475 221 -----------RIQRERfpdpgAYAsvasGYRVTPEMLADVSDRFILMHPLP--RVDEIDPQV-DSmPCARYFEQARNGV 286
Cdd:COG0078  228 dvwvsmgqeeeAEERIK-----AFK----PYQVNEELMALAKPDAIFMHCLPahRGEEVTDEViDG-PQSVVFDEAENRL 297


                 ....*..
gi 973165475 287 PIRMAML 293
Cdd:COG0078  298 HAQKALL 304
PRK00779 PRK00779
ornithine carbamoyltransferase; Provisional
 1-284 3.38e-50

ornithine carbamoyltransferase; Provisional


Pssm-ID: 234835 [Multi-domain]  Cd Length: 304  Bit Score: 167.96  E-value: 3.38e-50
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973165475   1 MRHIISINEVSTEEIDDILDRASAIEEGAYDPD---LLNGKILANLFFEPSTRTQMSFVSAMFRLGGKVINLGSIEaSSI 77
Cdd:PRK00779   4 GRHFLSLDDLSPEELEELLDLAAELKKKRKAGEphpPLKGKTLAMIFEKPSTRTRVSFEVGMAQLGGHAIFLSPRD-TQL 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973165475  78 AKGETLADTIRVVSGYADAIVLR---HpkEGAARLAsEFSDVPVINA-GDGAgqHPSQTLLDLFTIRQSF-PLNGINVGF 152
Cdd:PRK00779  83 GRGEPIEDTARVLSRYVDAIMIRtfeH--ETLEELA-EYSTVPVINGlTDLS--HPCQILADLLTIYEHRgSLKGLKVAW 157

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973165475 153 LGDlryGRT-AHSLATALSRYGVIIHTITPPGLELPPSLTHDL-LDTGTKIVVHEHLEDIIADLDVLYvT---------- 220
Cdd:PRK00779 158 VGD---GNNvANSLLLAAALLGFDLRVATPKGYEPDPEIVEKIaKETGASIEVTHDPKEAVKGADVVY-Tdvwvsmgqea 233

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 973165475 221 -RIQRER-FPdpgayasvasGYRVTPEMLADVSDRFILMHPLP--RVDEIDPQV-DSmPCARYFEQARN 284
Cdd:PRK00779 234 eAEERLKaFA----------PYQVNEELMALAKPDAIFMHCLPahRGEEVTDEViDG-PQSVVWDEAEN 291
pyrB PRK13814
aspartate carbamoyltransferase;
3-298 9.03e-46

aspartate carbamoyltransferase;


Pssm-ID: 139876 [Multi-domain]  Cd Length: 310  Bit Score: 156.80  E-value: 9.03e-46
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973165475   3 HIISINEVSTEEIDDILDRASAIEEGAYDP----DLLNGKILANLFFEPSTRTQMSFVSAMFRLGGKVINlGSIEASSIA 78
Cdd:PRK13814   7 HLLNMRSLTRDHIEKLIQRANYFLTQGMEKnsvfETLKGHVVANLFFEPSTRTRNSFEIAAKRLGAMVLN-PNLKISAIS 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973165475  79 KGETLADTIRVVSGYADAI-VLRHPK-EGAARLASEFSDVPVINAGDGAGQHPSQTLLDLFTIRQSFP-LNGINVGFLGD 155
Cdd:PRK13814  86 KGETLFDTIKTLEAMGVYFfIVRHSEnETPEQIAKQLSSGVVINAGDGNHQHPSQALIDLMTIKQHKPhWNKLCVTIIGD 165

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973165475 156 LRYGRTAHSLATALSRYGVIIHTITPPGLELPPSLTHDLLDTGTKivvhehLEDIIADLDVLYVTRIQRERFPDPGAYAS 235
Cdd:PRK13814 166 IRHSRVANSLMDGLVTMGVPEIRLVGPSSLLPDKVGNDSIKKFTE------LKPSLLNSDVIVTLRLQKERHDNSVDIDA 239

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 973165475 236 VASGYRVTPEMLADVSDRFILMHPLP--RVDEIDPQVDSMPCARYFEQARNGVPIRMAMLQKVLV 298
Cdd:PRK13814 240 FRGSFRLTPEKLYSAKPDAIVMHPGPvnREVEINSDVADNQQSVILQQVRNGVAMRMAVLELFLL 304
OTCace pfam00185
Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain;
149-293 6.41e-35

Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain;


Pssm-ID: 425511 [Multi-domain]  Cd Length: 154  Bit Score: 123.87  E-value: 6.41e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973165475  149 NVGFLGDLrYGRTAHSLATALSRYGVIIHTITPPGLELPPSLT----HDLLDTGTKIVVHEHLEDIIADLDVLYVTRIQ- 223
Cdd:pfam00185   1 KIAYVGDG-HNNVAHSLIIAAAKLGMDVRLATPKGYPPDPEVLdkakKIAEKSGGSIEITDDPAEAVKGADVVYTDVWQs 79

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 973165475  224 ----RERFPDPGAYAsvasGYRVTPEMLADVSDRFILMHPLP--RVDEIDPQVDSMPCARYFEQARNGVPIRMAML 293
Cdd:pfam00185  80 mgqeKEREERLKAFK----PYQVNEELMKLAKKDAIFMHCLPahRGEEVTDDVFDGPRSVVFDQAENRLHAQKALL 151
pyrB PRK13376
bifunctional aspartate carbamoyltransferase catalytic subunit/aspartate carbamoyltransferase ...
 43-293 1.13e-32

bifunctional aspartate carbamoyltransferase catalytic subunit/aspartate carbamoyltransferase regulatory subunit; Provisional


Pssm-ID: 237369 [Multi-domain]  Cd Length: 525  Bit Score: 126.03  E-value: 1.13e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973165475  43 LFFEPSTRTQMSFV-SAMFRLGGKViNLGSIEASSIAKGETLADTIRVVSGYADA--IVLRHPKEGAARL----ASEFS- 114
Cdd:PRK13376  56 VFVEPSTRTKESFInAAKFHKNVKV-NIFDSEHSSFNKQESYTDTFNMLTGYSDYsiFIVRTRLEGVCRLleekVSEFAs 134

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973165475 115 ----DVPV-INAGDGAGQHPSQTLLDLFTI--RQSFPLNGINVGFLGDLRYGRTAHSLATALSRYG-VIIHTITPPGLEL 186
Cdd:PRK13376 135 rngiEVPAfINAGDGKHEHPTQELLDEFTFleQNNFDNSFIHIALVGDLLHGRTVHSKVNGLKIFKnVKVDLIAPEELAM 214

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973165475 187 PPSLTHDLLDTGTKIVVHEHLEDIIADLDVL---YVTRIQRERFPDPGAYASVASGYRVT--PEMLADVSDRFILMHPLP 261
Cdd:PRK13376 215 PEHYVEKMKKNGFEVRIFSSIEEYLSQKDVAkiwYFTRLQLERMGEDILEKEHILRKAVTfrKEFLDKLPEGVKFYHPLP 294

                        250       260       270
                 ....*....|....*....|....*....|....*.
gi 973165475 262 RvDEIDPQV----DSMPCARYFEQARNGVPIRMAML 293
Cdd:PRK13376 295 R-HKVYPTIptflDTLPLNGWETQAINGYWVRIVLL 329
PLN02342 PLN02342
ornithine carbamoyltransferase
 1-297 7.68e-32

ornithine carbamoyltransferase


Pssm-ID: 177976 [Multi-domain]  Cd Length: 348  Bit Score: 121.05  E-value: 7.68e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973165475   1 MRHIISINEVSTEEIDDILDRASAIE------EGAYDPdlLNGKILANLFFEPSTRTQMSFVSAMFRLGGKVINLGSiEA 74
Cdd:PLN02342  45 PKHFLHIDDFDKEEILGLLDRAKEVKallksgDRSFQP--FKGKSMAMIFTKPSMRTRVSFETGFFLLGGHALYLGP-DD 121

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973165475  75 SSIAKGETLADTIRVVSGYADAIVLR---HpkEGAARLAsEFSDVPVINaGDGAGQHPSQTLLDLFTIRQSF-PLNGINV 150
Cdd:PLN02342 122 IQLGKREETRDIARVLSRYNDIIMARvfaH--QDVLDLA-EYSSVPVIN-GLTDYNHPCQIMADALTIIEHIgRLEGTKV 197

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973165475 151 GFLGDlryGRT-AHSLATALSRYGVIIHTITPPGLELPPSLTHDLLDTGT-KIVVHEHLEDIIADLDVLY----VTRIQR 224
Cdd:PLN02342 198 VYVGD---GNNiVHSWLLLAAVLPFHFVCACPKGYEPDAKTVEKARAAGIsKIEITNDPAEAVKGADVVYtdvwASMGQK 274

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 973165475 225 ErfpDPGAYASVASGYRVTPEMLADVSDRFILMHPLP--RVDEIDPQVDSMPCARYFEQARNGVPIRMAMLQKVL 297
Cdd:PLN02342 275 E---EAEKRKKAFQGFQVNEALMKLAGPQAYFMHCLPaeRGVEVTDGVMEAPNSIVFPQAENRMHAQNAIMLHQL 346
PRK02102 PRK02102
ornithine carbamoyltransferase; Validated
 2-298 1.56e-31

ornithine carbamoyltransferase; Validated


Pssm-ID: 179366 [Multi-domain]  Cd Length: 331  Bit Score: 119.61  E-value: 1.56e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973165475   2 RHIISINEVSTEEIDDILDRASAIEEGAY---DPDLLNGKILANLFFEPSTRTQMSFVSAMFRLGGKVINLGSIEaSSIA 78
Cdd:PRK02102   8 RSFLKLLDFTPEEIEYLIDLSIELKAAKKagiEHQYLEGKNIALIFEKTSTRTRCAFEVAAIDLGAHVTYLGPND-SQLG 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973165475  79 KGETLADTIRVVSGYADAIVLRHPKEGAARLASEFSDVPVINAGDGAgQHPSQTLLDLFTIRQSF-PLNGINVGFLGDLR 157
Cdd:PRK02102  87 KKESIEDTARVLGRMYDGIEYRGFKQEIVEELAKYSGVPVWNGLTDE-WHPTQMLADFMTMKEHFgPLKGLKLAYVGDGR 165

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973165475 158 YgRTAHSLATALSRYGVIIHTITPPGLElpPSltHDLLD--------TGTKIVVHEHLEDIIADLDVLY----------V 219
Cdd:PRK02102 166 N-NMANSLMVGGAKLGMDVRICAPKELW--PE--EELVAlareiakeTGAKITITEDPEEAVKGADVIYtdvwvsmgeeD 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973165475 220 TRIQRERFPDPgayasvasgYRVTPEMLADVS-DRFILMHPLPRVDEIDPQVDSMPCARY-------------------F 279
Cdd:PRK02102 241 EWEERIKLLKP---------YQVNMDLMKATGnPDVIFMHCLPAFHDTETKVGKEIAEKYglkglevtdevfeskysivF 311

                        330
                 ....*....|....*....
gi 973165475 280 EQARNgvpiRMAMLQKVLV 298
Cdd:PRK02102 312 DEAEN----RMHTIKAVMV 326
PRK04284 PRK04284
ornithine carbamoyltransferase; Provisional
 2-270 6.72e-26

ornithine carbamoyltransferase; Provisional


Pssm-ID: 235269 [Multi-domain]  Cd Length: 332  Bit Score: 104.44  E-value: 6.72e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973165475   2 RHIISINEVSTEEIDDILDRASAIEEGAY---DPDLLNGKILANLFFEPSTRTQMSFVSAMFRLGGKVINLGSiEASSIA 78
Cdd:PRK04284   7 RSFLTLLDFTPKEIEYLLDLSEDLKRAKYagiEVQKLKGKNIALIFEKDSTRTRCAFEVAAYDQGAHVTYLGP-TGSQMG 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973165475  79 KGETLADTIRVVSGYADAIVLRHPKEGAARLASEFSDVPVINaGDGAGQHPSQTLLDLFTIRQSF--PLNGINVGFLGDL 156
Cdd:PRK04284  86 KKESTKDTARVLGGMYDGIEYRGFSQRTVETLAEYSGVPVWN-GLTDEDHPTQVLADFLTAKEHLkkPYKDIKFTYVGDG 164

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973165475 157 RyGRTAHSLATALSRYGVIIHTITPPglELPPslTHDLLD--------TGTKIVVHEHLEDIIADLDVLYV--------- 219
Cdd:PRK04284 165 R-NNVANALMQGAAIMGMDFHLVCPK--ELNP--DDELLNkckeiaaeTGGKITITDDIDEGVKGSDVIYTdvwvsmgep 239

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|..
gi 973165475 220 TRIQRERFpdpgayaSVASGYRVTPEMLADVSD-RFILMHPLPRVDEIDPQV 270
Cdd:PRK04284 240 DEVWEERI-------KLLKPYQVNKEMMKKTGNpNAIFEHCLPSFHDLDTKV 284
PRK14805 PRK14805
ornithine carbamoyltransferase; Provisional
 1-298 4.32e-23

ornithine carbamoyltransferase; Provisional


Pssm-ID: 237819 [Multi-domain]  Cd Length: 302  Bit Score: 96.30  E-value: 4.32e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973165475   1 MRHIISINEVSTEEIDDILDRASAIEEgayDP----DLLNGKILANLFFEPSTRTQMSFVSAMFRLGGKVINLGSiEASS 76
Cdd:PRK14805   1 MKHLLSIKELTQQQLLDLLALAKTIKA---NPaeyrQALAGKSVVMLFEKPSLRTRVSFDIGINKLGGHCLYLDQ-QNGA 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973165475  77 IAKGETLADTIRVVSGYADAIVLR----HPKEGAArlasEFSDVPVINA-GDgaGQHPSQTLLDLFTIRQSFP-LNGINV 150
Cdd:PRK14805  77 LGKRESVADFAANLSCWADAIVARvfshSTIEQLA----EHGSVPVINAlCD--LYHPCQALADFLTLAEQFGdVSKVKL 150

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973165475 151 GFLGDlryG-RTAHSLATALSRYGVIIHTITPPGLELPP---SLTHDLL-DTGTKIVVHEHLEDiIADLDVLYV-TRIQr 224
Cdd:PRK14805 151 AYVGD---GnNVTHSLMYGAAILGATMTVICPPGHFPDGqivAEAQELAaKSGGKLVLTSDIEA-IEGHDAIYTdTWIS- 225

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 973165475 225 erFPDPGAYASVASG---YRVTPEMLADVSDRFIlMHPLP--RVDEIDPQVDSMPCARYFEQARNgvpiRMAMLQKVLV 298
Cdd:PRK14805 226 --MGDDTPLAEIKAKfapYQVNKALMEKAGATFV-MHCQPahRGVEITSEVMDGEGSLILQQAEN----RMHAQNAVLV 297
PRK04523 PRK04523
N-acetylornithine carbamoyltransferase; Reviewed
 1-296 5.90e-21

N-acetylornithine carbamoyltransferase; Reviewed


Pssm-ID: 235304 [Multi-domain]  Cd Length: 335  Bit Score: 90.96  E-value: 5.90e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973165475   1 MRHIISINEVSTEEIDDILDRASAIEEGAYDPdLLNGKILANLFFEPSTRTQMSFVSAMFRLGGKVINL--GS------I 72
Cdd:PRK04523   3 LKHFLNTQDWSRAELDALLTQAAAFKRNKLGS-ALKGKSIALVFFNPSLRTRTSFELGAFQLGGHAVVLqpGKdawpieF 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973165475  73 EASSIAKGET---LADTIRVVSGYADAIVLR-HPK---------EGAARLASEFSDVPVINAGDGAgqHPSQTLLDLFTI 139
Cdd:PRK04523  82 ELGAVMDGETeehIREVARVLSRYVDLIGVRaFPKfvdwskdrqDQVLNSFAKYSTVPVINMETIT--HPCQELAHALAL 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973165475 140 RQSFplnginvgflGDLRYGRT----------------AHSLATALSRYGVIIHTITP-PGLELPP----SLTHDLLDTG 198
Cdd:PRK04523 160 QEHF----------GTTLRGKKyvltwtyhpkplntavANSALLIATRLGMDVTLLCPtPDYILDErymdWAEQNAAESG 229

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973165475 199 TKIVVHEHLEDIIADLDVLYV----TRIQRERFPDPGAYASVASGYRVTPEMLADVSDRfILMHPLP--RVDEIDPQVDS 272
Cdd:PRK04523 230 GSLTVSHDIDSAYAGADVVYAkswgALPFFGNWEPEKPIRDQYQHFIVDERKMALTNNG-VFSHCLPlrRNVKVTDAVMD 308

                        330       340
                 ....*....|....*....|....
gi 973165475 273 MPCARYFEQARNGVPIRMAMLQKV 296
Cdd:PRK04523 309 SPNCIAIDEAENRLHVQKAIMAAL 332
PRK01713 PRK01713
ornithine carbamoyltransferase; Provisional
 2-298 8.72e-21

ornithine carbamoyltransferase; Provisional


Pssm-ID: 167263 [Multi-domain]  Cd Length: 334  Bit Score: 90.43  E-value: 8.72e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973165475   2 RHIISINEVSTEEIDDILDRASAIEEGAY---DPDLLNGKILANLFFEPSTRTQMSFVSAMFRLGGKVINLGSIeASSIA 78
Cdd:PRK01713   8 RHLLSLVNHTEREIKYLLDLSRDLKRAKYagtEQQRLKGKNIALIFEKTSTRTRCAFEVAAYDQGAQVTYIDPN-SSQIG 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973165475  79 KGETLADTIRVVSGYADAIVLRHPKEGAARLASEFSDVPVINaGDGAGQHPSQTLLDLFTIRQSF--PLNGINVGFLGDL 156
Cdd:PRK01713  87 HKESMKDTARVLGRMYDAIEYRGFKQSIVNELAEYAGVPVFN-GLTDEFHPTQMLADVLTMIENCdkPLSEISYVYIGDA 165

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973165475 157 RyGRTAHSLATALSRYGVIIHTITPPGLeLPPSLTHDLL-----DTGTKIVVHEHLEDIIADLDVLY--VTRIQRERFPD 229
Cdd:PRK01713 166 R-NNMGNSLLLIGAKLGMDVRICAPKAL-LPEASLVEMCekfakESGARITVTDDIDKAVKGVDFVHtdVWVSMGEPLET 243

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973165475 230 PGAYASVASGYRVTPEMLADVSD-RFILMHPLPRVDEIDPQVDSMPCARY---------------------FEQARNgvp 287
Cdd:PRK01713 244 WGERIKLLMPYQVTPELMKRTGNpKVKFMHCLPAFHNSETKVGRQIAEKYpelangievtedvfespmniaFEQAEN--- 320

                        330
                 ....*....|.
gi 973165475 288 iRMAMLQKVLV 298
Cdd:PRK01713 321 -RMHTIKAVMV 330
PRK14804 PRK14804
ornithine carbamoyltransferase; Provisional
 1-297 6.37e-17

ornithine carbamoyltransferase; Provisional


Pssm-ID: 173265 [Multi-domain]  Cd Length: 311  Bit Score: 79.30  E-value: 6.37e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973165475   1 MRHIISINEVSTEEIDDILDRASAIEEG-AYDPDLLNGKILANLFFEPSTRTQMSFVSAMFRLGGKVINLgsieaSSIAK 79
Cdd:PRK14804   6 VKHLISWEDWSDSEILDLLDFAVHVKKNrVNYAGHMSGRSLAMLFQKTSTRTRVSFEVAMTEMGGHGIYL-----DWMAS 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973165475  80 GETLADT---IRVVSGYADAIVLRHPKEGAARLASEFSDVPVINAGDGAGqHPSQTLLDLFTI---RQSFPLNGINVGFL 153
Cdd:PRK14804  81 NFQLSDIdleARYLSRNVSVIMARLKKHEDLLVMKNGSQVPVINGCDNMF-HPCQSLADIMTIaldSPEIPLNQKQLTYI 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973165475 154 GdlRYGRTAHSLATALSRYGVIIHTITPpgLELPPSLTHDLLDTGTK---IVVHEHLEDIIADLDVLYV-TRIQRERFPD 229
Cdd:PRK14804 160 G--VHNNVVNSLIGITAALGIHLTLVTP--IAAKENIHAQTVERAKKkgtLSWEMNLHKAVSHADYVYTdTWLDMEFFND 235

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 973165475 230 PgAYA-------SVASGYRVTPEMLADVSDRfiLMHPLP--RVDEIDPQVDSMPCARYFEQARNGVPIRMAMLQKVL 297
Cdd:PRK14804 236 P-SYAdkkkqrmELMMPYQINSSLMEKTNAK--VMHDMPihAGYEITREVVLSDRSIIFQQAENRLDAQKAVILKLL 309
PRK07200 PRK07200
aspartate/ornithine carbamoyltransferase family protein; Validated
 9-100 2.69e-06

aspartate/ornithine carbamoyltransferase family protein; Validated


Pssm-ID: 235961 [Multi-domain]  Cd Length: 395  Bit Score: 48.20  E-value: 2.69e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973165475   9 EVSTEEIDDILDRASAIE---EGAYDPDLLNGKILANLFFEPSTRTQMSFVSAMFRLGGKVINLGSiEASSIAKGETLAD 85
Cdd:PRK07200  28 EKTPDELKAVLDVADALRalrEENISTKVFNSGLGISVFRDNSTRTRFSYASACNLLGLEVQDLDE-GKSQIAHGETVRE 106

                         90
                 ....*....|....*
gi 973165475  86 TIRVVSGYADAIVLR 100
Cdd:PRK07200 107 TANMISFMADVIGIR 121
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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