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Conserved domains on  [gi|972942279|gb|ALW85099|]
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oxidoreductase [Hymenobacter sedentarius]

Protein Classification

FAD-dependent oxidoreductase( domain architecture ID 11429752)

FAD-dependent oxidoreductase containing a Rieske (2Fe-2S)-binding domain

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
DadA COG0665
Glycine/D-amino acid oxidase (deaminating) [Amino acid transport and metabolism];
36-412 1.34e-59

Glycine/D-amino acid oxidase (deaminating) [Amino acid transport and metabolism];


:

Pssm-ID: 440429 [Multi-domain]  Cd Length: 364  Bit Score: 200.90  E-value: 1.34e-59
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 972942279  36 TTTDVVIVGGGIAGLTTAYLLSKEGHKVLLLEDGELASGESGRTTAHLSYALDDRYATLENLFGREGAQLaaeshasaid 115
Cdd:COG0665    1 ATADVVVIGGGIAGLSTAYHLARRGLDVTVLERGRPGSGASGRNAGQLRPGLAALADRALVRLAREALDL---------- 70

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 972942279 116 kIEQIVQAEQIDCDFTRLDGFLFLHADGTHQELMEERDAAHRAGLPaVEWLPNAGTTGFEPG-------ECLRWPGQGQF 188
Cdd:COG0665   71 -WRELAAELGIDCDFRRTGVLYLARTEAELAALRAEAEALRALGLP-VELLDAAELREREPGlgspdyaGGLYDPDDGHV 148

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 972942279 189 HILKYLAGLTQAIVLQGGRICTRTHVSEV--HGGPHAHIVTEDGTVaRAkRAIVVATN---TPFNDRVVMHTKQHPYRTY 263
Cdd:COG0665  149 DPAKLVRALARAARAAGVRIREGTPVTGLerEGGRVTGVRTERGTV-RA-DAVVLAAGawsARLLPMLGLRLPLRPVRGY 226

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 972942279 264 VVGARVPKGSVTKALYWDMAdpyHYVRlqevsagPRGGqtdyDLLIVGGEDHKTGQADDPS-AHLRCLEEWTRDRFPMVR 342
Cdd:COG0665  227 VLVTEPLPDLPLRPVLDDTG---VYLR-------PTAD----GRLLVGGTAEPAGFDRAPTpERLEALLRRLRRLFPALA 292

                        330       340       350       360       370       380       390
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 972942279 343 DFE--YRWSGQVMEPTDGLGYAGRNPlDADNVFIITGDSGHGMTHGTLGPMVVADLLAGRDNAW-AKLYDPGR 412
Cdd:COG0665  293 DAEivRAWAGLRPMTPDGLPIIGRLP-GAPGLYVATGHGGHGVTLAPAAGRLLADLILGGEPPLdLAPFSPDR 364
Rieske_YhfW_C cd03477
YhfW family, C-terminal Rieske domain; YhfW is a protein of unknown function with an ...
 442-524 1.41e-38

YhfW family, C-terminal Rieske domain; YhfW is a protein of unknown function with an N-terminal DadA-like (glycine/D-amino acid dehydrogenase) domain and a C-terminal Rieske domain. The Rieske domain is a [2Fe-2S] cluster binding domain involved in electron transfer. It is commonly found in Rieske non-heme iron oxygenase (RO) systems such as naphthalene and biphenyl dioxygenases, as well as in plant/cyanobacterial chloroplast b6f and mitochondrial cytochrome bc(1) complexes. YhfW is found in bacteria, some eukaryotes and archaea.


:

Pssm-ID: 239559 [Multi-domain]  Cd Length: 91  Bit Score: 135.90  E-value: 1.41e-38
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 972942279 442 DVSTVEEIPNGSGAVMRRGITKVAVYKDEKGAVHECSAICPHLHCVVHWNGLEKSWDCPCHGSRFTALGELLSGPANTGL 521
Cdd:cd03477    1 DITDIEDLAPGEGGVVNIGGKRLAVYRDEDGVLHTVSATCTHLGCIVHWNDAEKSWDCPCHGSRFSYDGEVIEGPAVSGL 80


                 ...
gi 972942279 522 APA 524
Cdd:cd03477   81 KPA 83
 
Name Accession Description Interval E-value
DadA COG0665
Glycine/D-amino acid oxidase (deaminating) [Amino acid transport and metabolism];
36-412 1.34e-59

Glycine/D-amino acid oxidase (deaminating) [Amino acid transport and metabolism];


Pssm-ID: 440429 [Multi-domain]  Cd Length: 364  Bit Score: 200.90  E-value: 1.34e-59
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 972942279  36 TTTDVVIVGGGIAGLTTAYLLSKEGHKVLLLEDGELASGESGRTTAHLSYALDDRYATLENLFGREGAQLaaeshasaid 115
Cdd:COG0665    1 ATADVVVIGGGIAGLSTAYHLARRGLDVTVLERGRPGSGASGRNAGQLRPGLAALADRALVRLAREALDL---------- 70

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 972942279 116 kIEQIVQAEQIDCDFTRLDGFLFLHADGTHQELMEERDAAHRAGLPaVEWLPNAGTTGFEPG-------ECLRWPGQGQF 188
Cdd:COG0665   71 -WRELAAELGIDCDFRRTGVLYLARTEAELAALRAEAEALRALGLP-VELLDAAELREREPGlgspdyaGGLYDPDDGHV 148

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 972942279 189 HILKYLAGLTQAIVLQGGRICTRTHVSEV--HGGPHAHIVTEDGTVaRAkRAIVVATN---TPFNDRVVMHTKQHPYRTY 263
Cdd:COG0665  149 DPAKLVRALARAARAAGVRIREGTPVTGLerEGGRVTGVRTERGTV-RA-DAVVLAAGawsARLLPMLGLRLPLRPVRGY 226

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 972942279 264 VVGARVPKGSVTKALYWDMAdpyHYVRlqevsagPRGGqtdyDLLIVGGEDHKTGQADDPS-AHLRCLEEWTRDRFPMVR 342
Cdd:COG0665  227 VLVTEPLPDLPLRPVLDDTG---VYLR-------PTAD----GRLLVGGTAEPAGFDRAPTpERLEALLRRLRRLFPALA 292

                        330       340       350       360       370       380       390
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 972942279 343 DFE--YRWSGQVMEPTDGLGYAGRNPlDADNVFIITGDSGHGMTHGTLGPMVVADLLAGRDNAW-AKLYDPGR 412
Cdd:COG0665  293 DAEivRAWAGLRPMTPDGLPIIGRLP-GAPGLYVATGHGGHGVTLAPAAGRLLADLILGGEPPLdLAPFSPDR 364
DAO pfam01266
FAD dependent oxidoreductase; This family includes various FAD dependent oxidoreductases: ...
 39-396 8.29e-46

FAD dependent oxidoreductase; This family includes various FAD dependent oxidoreductases: Glycerol-3-phosphate dehydrogenase EC:1.1.99.5, Sarcosine oxidase beta subunit EC:1.5.3.1, D-alanine oxidase EC:1.4.99.1, D-aspartate oxidase EC:1.4.3.1.


Pssm-ID: 426168 [Multi-domain]  Cd Length: 339  Bit Score: 163.72  E-value: 8.29e-46
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 972942279   39 DVVIVGGGIAGLTTAYLLSKEGHKVLLLE-DGELASGESGRTTAHLSYALDDryatLENlfgREGAQLAAEshasAIDKI 117
Cdd:pfam01266   1 DVVVIGGGIVGLSTAYELARRGLSVTLLErGDDPGSGASGRNAGLIHPGLRY----LEP---SELARLALE----ALDLW 69

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 972942279  118 EQIVQAEQIDCDFtRLDGFLFLHADGTHQELMEERDAAHRAGLPaVEWLPNAGTTGFEPGE-----CLRWPGQGQFHILK 192
Cdd:pfam01266  70 EELEEELGIDCGF-RRCGVLVLARDEEEEALEKLLAALRRLGVP-AELLDAEELRELEPLLpglrgGLFYPDGGHVDPAR 147

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 972942279  193 YLAGLTQAIVLQGGRICTRTHVSEVHGGPHAHIVTEDGTVarakRAIVVATN--TPFNDRVVMHTKQHPYRTY--VVGAR 268
Cdd:pfam01266 148 LLRALARAAEALGVRIIEGTEVTGIEEEGGVWGVVTTGEA----DAVVNAAGawADLLALPGLRLPVRPVRGQvlVLEPL 223

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 972942279  269 VPKGSVTKALYWDMADPYHYVRlqevsagprggQTDYDLLIVGG--EDHKTGQADDPSAHLRCLEEWTRDRFPMVRDFEY 346
Cdd:pfam01266 224 PEALLILPVPITVDPGRGVYLR-----------PRADGRLLLGGtdEEDGFDDPTPDPEEIEELLEAARRLFPALADIER 292

                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|
gi 972942279  347 RWSGqVMEPTDGLGYAGRnpLDADNVFIITGDSGHGMTHGTLGPMVVADL 396
Cdd:pfam01266 293 AWAG-LRPLPDGLPIIGR--PGSPGLYLATGHGGHGLTLAPGIGKLLAEL 339
Rieske_YhfW_C cd03477
YhfW family, C-terminal Rieske domain; YhfW is a protein of unknown function with an ...
 442-524 1.41e-38

YhfW family, C-terminal Rieske domain; YhfW is a protein of unknown function with an N-terminal DadA-like (glycine/D-amino acid dehydrogenase) domain and a C-terminal Rieske domain. The Rieske domain is a [2Fe-2S] cluster binding domain involved in electron transfer. It is commonly found in Rieske non-heme iron oxygenase (RO) systems such as naphthalene and biphenyl dioxygenases, as well as in plant/cyanobacterial chloroplast b6f and mitochondrial cytochrome bc(1) complexes. YhfW is found in bacteria, some eukaryotes and archaea.


Pssm-ID: 239559 [Multi-domain]  Cd Length: 91  Bit Score: 135.90  E-value: 1.41e-38
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 972942279 442 DVSTVEEIPNGSGAVMRRGITKVAVYKDEKGAVHECSAICPHLHCVVHWNGLEKSWDCPCHGSRFTALGELLSGPANTGL 521
Cdd:cd03477    1 DITDIEDLAPGEGGVVNIGGKRLAVYRDEDGVLHTVSATCTHLGCIVHWNDAEKSWDCPCHGSRFSYDGEVIEGPAVSGL 80


                 ...
gi 972942279 522 APA 524
Cdd:cd03477   81 KPA 83
QcrA/PetC COG0723
Rieske Fe-S protein [Energy production and conversion];
446-522 7.32e-24

Rieske Fe-S protein [Energy production and conversion];


Pssm-ID: 440487 [Multi-domain]  Cd Length: 118  Bit Score: 96.61  E-value: 7.32e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 972942279 446 VEEIPNGSGAVMRRGITKVAVYK---DEKGAVHECSAICPHLHCVVHWNGLEKSWDCPCHGSRFTALGELLSGPANTGLA 522
Cdd:COG0723   23 LSDLPPGEGKVVEWRGKPVFVVRtpvRGDGEIVAVSAICTHLGCPVTWNADEGGFDCPCHGSRFDPDGRVLKGPAPRPLP 102
PRK13474 PRK13474
cytochrome b6-f complex iron-sulfur subunit; Provisional
 469-522 1.37e-12

cytochrome b6-f complex iron-sulfur subunit; Provisional


Pssm-ID: 237392 [Multi-domain]  Cd Length: 178  Bit Score: 66.21  E-value: 1.37e-12
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 972942279 469 DEKGAVHE--CSAICPHLHCVVHWNGLEKSWDCPCHGSRFTALGELLSGPANTGLA 522
Cdd:PRK13474  93 EEDGTIASygINAVCTHLGCVVPWNSGENKFQCPCHGSQYDATGKVVRGPAPLSLA 148
Rieske pfam00355
Rieske [2Fe-2S] domain; The rieske domain has a [2Fe-2S] centre. Two conserved cysteines ...
 446-522 1.02e-10

Rieske [2Fe-2S] domain; The rieske domain has a [2Fe-2S] centre. Two conserved cysteines coordinate one Fe ion, while the other Fe ion is coordinated by two conserved histidines. In hyperthermophilic archaea there is a SKTPCX(2-3)C motif at the C-terminus. The cysteines in this motif form a disulphide bridge, which stabilizes the protein.


Pssm-ID: 425632 [Multi-domain]  Cd Length: 89  Bit Score: 58.13  E-value: 1.02e-10
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 972942279  446 VEEIPNGSGAVMRRGITKVAVYKDEKGAVHECSAICPHLHC-VVHWNGLEKSW-DCPCHGSRFTALGELLSGPANTGLA 522
Cdd:pfam00355   8 SSELPEGEPKVVEVGGEPLVVFRDEDGELYALEDRCPHRGApLSEGKVNGGGRlECPYHGWRFDGTGKVVKVPAPRPLK 86
Rieske_proteo TIGR01416
ubiquinol-cytochrome c reductase, iron-sulfur subunit; This model represents the ...
 479-522 4.91e-07

ubiquinol-cytochrome c reductase, iron-sulfur subunit; This model represents the Proteobacterial and mitochondrial type of the Rieske [2Fe-2S] iron-sulfur as found in ubiquinol-cytochrome c reductase. The model excludes the Rieske iron-sulfur protein as found in the cytochrome b6-f complex of the Cyanobacteria and chloroplasts. Most members of this family have a recognizable twin-arginine translocation (tat) signal sequence (DeltaPh-dependent translocation in chloroplast) for transport across the membrane with the 2Fe-2S group already bound. These signal sequences include a motif resembling RRxFLK before the transmembrane helix. [Energy metabolism, Electron transport]


Pssm-ID: 273610 [Multi-domain]  Cd Length: 174  Bit Score: 49.69  E-value: 4.91e-07
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*..
gi 972942279  479 AICPHLHCVVHWNGLEKS---WDCPCHGSRFTALGELLSGPANTGLA 522
Cdd:TIGR01416 113 GICTHLGCIPTYGPEEGDkggFFCPCHGSHYDTAGRVRKGPAPLNLP 159
PLN02612 PLN02612
phytoene desaturase
 14-102 3.53e-06

phytoene desaturase


Pssm-ID: 215330 [Multi-domain]  Cd Length: 567  Bit Score: 49.46  E-value: 3.53e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 972942279  14 ATISSWFGTAPalPPFEPLaedtttDVVIVGGGIAGLTTAYLLSKEGHKVLLLE-----DGELAS-----GESGRTTAHL 83
Cdd:PLN02612  78 AALSASFRSAP--RPAKPL------KVVIAGAGLAGLSTAKYLADAGHKPILLEardvlGGKVAAwkdedGDWYETGLHI 149

                         90
                 ....*....|....*....
gi 972942279  84 SYAlddRYATLENLFGREG 102
Cdd:PLN02612 150 FFG---AYPNVQNLFGELG 165
GG-red-SF TIGR02032
geranylgeranyl reductase family; This model represents a subfamily which includes ...
 39-71 8.23e-06

geranylgeranyl reductase family; This model represents a subfamily which includes geranylgeranyl reductases involved in chlorophyll and bacteriochlorophyll biosynthesis as well as other related enzymes which may also act on geranylgeranyl groups or related substrates. [Biosynthesis of cofactors, prosthetic groups, and carriers, Chlorophyll and bacteriochlorphyll]


Pssm-ID: 273936 [Multi-domain]  Cd Length: 295  Bit Score: 47.70  E-value: 8.23e-06
                          10        20        30
                  ....*....|....*....|....*....|...
gi 972942279   39 DVVIVGGGIAGLTTAYLLSKEGHKVLLLEDGEL 71
Cdd:TIGR02032   2 DVVVVGAGPAGASAAYRLADKGLRVLLLEKKSF 34
 
Name Accession Description Interval E-value
DadA COG0665
Glycine/D-amino acid oxidase (deaminating) [Amino acid transport and metabolism];
36-412 1.34e-59

Glycine/D-amino acid oxidase (deaminating) [Amino acid transport and metabolism];


Pssm-ID: 440429 [Multi-domain]  Cd Length: 364  Bit Score: 200.90  E-value: 1.34e-59
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 972942279  36 TTTDVVIVGGGIAGLTTAYLLSKEGHKVLLLEDGELASGESGRTTAHLSYALDDRYATLENLFGREGAQLaaeshasaid 115
Cdd:COG0665    1 ATADVVVIGGGIAGLSTAYHLARRGLDVTVLERGRPGSGASGRNAGQLRPGLAALADRALVRLAREALDL---------- 70

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 972942279 116 kIEQIVQAEQIDCDFTRLDGFLFLHADGTHQELMEERDAAHRAGLPaVEWLPNAGTTGFEPG-------ECLRWPGQGQF 188
Cdd:COG0665   71 -WRELAAELGIDCDFRRTGVLYLARTEAELAALRAEAEALRALGLP-VELLDAAELREREPGlgspdyaGGLYDPDDGHV 148

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 972942279 189 HILKYLAGLTQAIVLQGGRICTRTHVSEV--HGGPHAHIVTEDGTVaRAkRAIVVATN---TPFNDRVVMHTKQHPYRTY 263
Cdd:COG0665  149 DPAKLVRALARAARAAGVRIREGTPVTGLerEGGRVTGVRTERGTV-RA-DAVVLAAGawsARLLPMLGLRLPLRPVRGY 226

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 972942279 264 VVGARVPKGSVTKALYWDMAdpyHYVRlqevsagPRGGqtdyDLLIVGGEDHKTGQADDPS-AHLRCLEEWTRDRFPMVR 342
Cdd:COG0665  227 VLVTEPLPDLPLRPVLDDTG---VYLR-------PTAD----GRLLVGGTAEPAGFDRAPTpERLEALLRRLRRLFPALA 292

                        330       340       350       360       370       380       390
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 972942279 343 DFE--YRWSGQVMEPTDGLGYAGRNPlDADNVFIITGDSGHGMTHGTLGPMVVADLLAGRDNAW-AKLYDPGR 412
Cdd:COG0665  293 DAEivRAWAGLRPMTPDGLPIIGRLP-GAPGLYVATGHGGHGVTLAPAAGRLLADLILGGEPPLdLAPFSPDR 364
DAO pfam01266
FAD dependent oxidoreductase; This family includes various FAD dependent oxidoreductases: ...
 39-396 8.29e-46

FAD dependent oxidoreductase; This family includes various FAD dependent oxidoreductases: Glycerol-3-phosphate dehydrogenase EC:1.1.99.5, Sarcosine oxidase beta subunit EC:1.5.3.1, D-alanine oxidase EC:1.4.99.1, D-aspartate oxidase EC:1.4.3.1.


Pssm-ID: 426168 [Multi-domain]  Cd Length: 339  Bit Score: 163.72  E-value: 8.29e-46
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 972942279   39 DVVIVGGGIAGLTTAYLLSKEGHKVLLLE-DGELASGESGRTTAHLSYALDDryatLENlfgREGAQLAAEshasAIDKI 117
Cdd:pfam01266   1 DVVVIGGGIVGLSTAYELARRGLSVTLLErGDDPGSGASGRNAGLIHPGLRY----LEP---SELARLALE----ALDLW 69

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 972942279  118 EQIVQAEQIDCDFtRLDGFLFLHADGTHQELMEERDAAHRAGLPaVEWLPNAGTTGFEPGE-----CLRWPGQGQFHILK 192
Cdd:pfam01266  70 EELEEELGIDCGF-RRCGVLVLARDEEEEALEKLLAALRRLGVP-AELLDAEELRELEPLLpglrgGLFYPDGGHVDPAR 147

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 972942279  193 YLAGLTQAIVLQGGRICTRTHVSEVHGGPHAHIVTEDGTVarakRAIVVATN--TPFNDRVVMHTKQHPYRTY--VVGAR 268
Cdd:pfam01266 148 LLRALARAAEALGVRIIEGTEVTGIEEEGGVWGVVTTGEA----DAVVNAAGawADLLALPGLRLPVRPVRGQvlVLEPL 223

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 972942279  269 VPKGSVTKALYWDMADPYHYVRlqevsagprggQTDYDLLIVGG--EDHKTGQADDPSAHLRCLEEWTRDRFPMVRDFEY 346
Cdd:pfam01266 224 PEALLILPVPITVDPGRGVYLR-----------PRADGRLLLGGtdEEDGFDDPTPDPEEIEELLEAARRLFPALADIER 292

                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|
gi 972942279  347 RWSGqVMEPTDGLGYAGRnpLDADNVFIITGDSGHGMTHGTLGPMVVADL 396
Cdd:pfam01266 293 AWAG-LRPLPDGLPIIGR--PGSPGLYLATGHGGHGLTLAPGIGKLLAEL 339
Rieske_YhfW_C cd03477
YhfW family, C-terminal Rieske domain; YhfW is a protein of unknown function with an ...
 442-524 1.41e-38

YhfW family, C-terminal Rieske domain; YhfW is a protein of unknown function with an N-terminal DadA-like (glycine/D-amino acid dehydrogenase) domain and a C-terminal Rieske domain. The Rieske domain is a [2Fe-2S] cluster binding domain involved in electron transfer. It is commonly found in Rieske non-heme iron oxygenase (RO) systems such as naphthalene and biphenyl dioxygenases, as well as in plant/cyanobacterial chloroplast b6f and mitochondrial cytochrome bc(1) complexes. YhfW is found in bacteria, some eukaryotes and archaea.


Pssm-ID: 239559 [Multi-domain]  Cd Length: 91  Bit Score: 135.90  E-value: 1.41e-38
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 972942279 442 DVSTVEEIPNGSGAVMRRGITKVAVYKDEKGAVHECSAICPHLHCVVHWNGLEKSWDCPCHGSRFTALGELLSGPANTGL 521
Cdd:cd03477    1 DITDIEDLAPGEGGVVNIGGKRLAVYRDEDGVLHTVSATCTHLGCIVHWNDAEKSWDCPCHGSRFSYDGEVIEGPAVSGL 80


                 ...
gi 972942279 522 APA 524
Cdd:cd03477   81 KPA 83
QcrA/PetC COG0723
Rieske Fe-S protein [Energy production and conversion];
446-522 7.32e-24

Rieske Fe-S protein [Energy production and conversion];


Pssm-ID: 440487 [Multi-domain]  Cd Length: 118  Bit Score: 96.61  E-value: 7.32e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 972942279 446 VEEIPNGSGAVMRRGITKVAVYK---DEKGAVHECSAICPHLHCVVHWNGLEKSWDCPCHGSRFTALGELLSGPANTGLA 522
Cdd:COG0723   23 LSDLPPGEGKVVEWRGKPVFVVRtpvRGDGEIVAVSAICTHLGCPVTWNADEGGFDCPCHGSRFDPDGRVLKGPAPRPLP 102
Rieske cd03467
Rieske domain; a [2Fe-2S] cluster binding domain commonly found in Rieske non-heme iron ...
 443-523 2.56e-13

Rieske domain; a [2Fe-2S] cluster binding domain commonly found in Rieske non-heme iron oxygenase (RO) systems such as naphthalene and biphenyl dioxygenases, as well as in plant/cyanobacterial chloroplast b6f and mitochondrial cytochrome bc(1) complexes. The Rieske domain can be divided into two subdomains, with an incomplete six-stranded, antiparallel beta-barrel at one end, and an iron-sulfur cluster binding subdomain at the other. The Rieske iron-sulfur center contains a [2Fe-2S] cluster, which is involved in electron transfer, and is liganded to two histidine and two cysteine residues present in conserved sequences called Rieske motifs. In RO systems, the N-terminal Rieske domain of the alpha subunit acts as an electron shuttle that accepts electrons from a reductase or ferredoxin component and transfers them to the mononuclear iron in the alpha subunit C-terminal domain to be used for catalysis.


Pssm-ID: 239550 [Multi-domain]  Cd Length: 98  Bit Score: 65.97  E-value: 2.56e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 972942279 443 VSTVEEIPNGSGAVMRRGITKVAVYKDEKGAVHECSAICPHLHCVVHWNGLE-KSWDCPCHGSRFTAL-GELLSGPANTG 520
Cdd:cd03467    4 VGALSELPPGGGRVVVVGGGPVVVVRREGGEVYALSNRCTHQGCPLSEGEGEdGCIVCPCHGSRFDLRtGEVVSGPAPRP 83


                 ...
gi 972942279 521 LAP 523
Cdd:cd03467   84 LPK 86
Rieske_cytochrome_b6f cd03471
Iron-sulfur protein (ISP) component of the b6f complex family, Rieske domain; The Rieske ...
 479-522 1.21e-12

Iron-sulfur protein (ISP) component of the b6f complex family, Rieske domain; The Rieske domain is a [2Fe-2S] cluster binding domain involved in electron transfer. The cytochrome b6f complex from Mastigocladus laminosus, a thermophilic cyanobacterium, contains four large subunits, including cytochrome f, cytochrome b6, the Rieske ISP, and subunit IV; as well as four small hydrophobic subunits, PetG, PetL, PetM, and PetN. Rieske ISP, one of the large subunits of the cytochrome bc-type complexes, is involved in respiratory and photosynthetic electron transfer. The core of the chloroplast b6f complex is similar to the analogous respiratory cytochrome bc(1) complex, but the domain arrangement outside the core and the complement of prosthetic groups are strikingly different.


Pssm-ID: 239553  Cd Length: 126  Bit Score: 64.69  E-value: 1.21e-12
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....
gi 972942279 479 AICPHLHCVVHWNGLEKSWDCPCHGSRFTALGELLSGPANTGLA 522
Cdd:cd03471   53 AVCTHLGCVVPWNAAENKFKCPCHGSQYDATGKVVRGPAPLSLA 96
PRK13474 PRK13474
cytochrome b6-f complex iron-sulfur subunit; Provisional
 469-522 1.37e-12

cytochrome b6-f complex iron-sulfur subunit; Provisional


Pssm-ID: 237392 [Multi-domain]  Cd Length: 178  Bit Score: 66.21  E-value: 1.37e-12
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 972942279 469 DEKGAVHE--CSAICPHLHCVVHWNGLEKSWDCPCHGSRFTALGELLSGPANTGLA 522
Cdd:PRK13474  93 EEDGTIASygINAVCTHLGCVVPWNSGENKFQCPCHGSQYDATGKVVRGPAPLSLA 148
Rieske pfam00355
Rieske [2Fe-2S] domain; The rieske domain has a [2Fe-2S] centre. Two conserved cysteines ...
 446-522 1.02e-10

Rieske [2Fe-2S] domain; The rieske domain has a [2Fe-2S] centre. Two conserved cysteines coordinate one Fe ion, while the other Fe ion is coordinated by two conserved histidines. In hyperthermophilic archaea there is a SKTPCX(2-3)C motif at the C-terminus. The cysteines in this motif form a disulphide bridge, which stabilizes the protein.


Pssm-ID: 425632 [Multi-domain]  Cd Length: 89  Bit Score: 58.13  E-value: 1.02e-10
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 972942279  446 VEEIPNGSGAVMRRGITKVAVYKDEKGAVHECSAICPHLHC-VVHWNGLEKSW-DCPCHGSRFTALGELLSGPANTGLA 522
Cdd:pfam00355   8 SSELPEGEPKVVEVGGEPLVVFRDEDGELYALEDRCPHRGApLSEGKVNGGGRlECPYHGWRFDGTGKVVKVPAPRPLK 86
YobN COG1231
Monoamine oxidase [Amino acid transport and metabolism];
36-240 2.89e-09

Monoamine oxidase [Amino acid transport and metabolism];


Pssm-ID: 440844 [Multi-domain]  Cd Length: 440  Bit Score: 59.16  E-value: 2.89e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 972942279  36 TTTDVVIVGGGIAGLTTAYLLSKEGHKVLLLEdgelASGES-GRT-----------------------TAHLSYA----- 86
Cdd:COG1231    6 RGKDVVIVGAGLAGLAAARELRKAGLDVTVLE----ARDRVgGRVwtlrfgddglyaelgamrippshTNLLALArelgl 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 972942279  87 -LDDRY-ATLENLFGREGAQLAAESHASAIDKIEQIVQA--EQIDCDFT-------RLDGFLFLH------ADGTHQELM 149
Cdd:COG1231   82 pLEPFPnENGNALLYLGGKRVRAGEIAADLRGVAELLAKllRALAAALDpwahpaaELDRESLAEwlrrngASPSARRLL 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 972942279 150 EERDAAHRAG----LPAVEWLPNAGTTGFEPGEclRWPGQGQFHILKYLA-GLtqaivlqGGRICTRTHVSEV-HGGPHA 223
Cdd:COG1231  162 GLLGAGEYGAdpdeLSLLDLLRYAASAGGGAQQ--FRIVGGMDQLPRALAaEL-------GDRIRLGAPVTRIrQDGDGV 232

                        250
                 ....*....|....*..
gi 972942279 224 HIVTEDGTVARAKRAIV 240
Cdd:COG1231  233 TVTTDDGGTVRADAVIV 249
HemY COG1232
Protoporphyrinogen oxidase HemY/PPOX [Coenzyme transport and metabolism]; Protoporphyrinogen ...
 38-67 3.07e-08

Protoporphyrinogen oxidase HemY/PPOX [Coenzyme transport and metabolism]; Protoporphyrinogen oxidase HemY/PPOX is part of the Pathway/BioSystem: Heme biosynthesis


Pssm-ID: 440845 [Multi-domain]  Cd Length: 443  Bit Score: 55.99  E-value: 3.07e-08
                         10        20        30
                 ....*....|....*....|....*....|
gi 972942279  38 TDVVIVGGGIAGLTTAYLLSKEGHKVLLLE 67
Cdd:COG1232    2 KRVAVIGGGIAGLTAAYRLAKAGHEVTVLE 31
LhgO COG0579
L-2-hydroxyglutarate oxidase LhgO [Carbohydrate transport and metabolism];
34-78 3.79e-08

L-2-hydroxyglutarate oxidase LhgO [Carbohydrate transport and metabolism];


Pssm-ID: 440344 [Multi-domain]  Cd Length: 418  Bit Score: 55.54  E-value: 3.79e-08
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*..
gi 972942279  34 EDTTTDVVIVGGGIAGLTTAYLLSK-EGHKVLLLE-DGELASGESGR 78
Cdd:COG0579    1 MMEMYDVVIIGAGIVGLALARELSRyEDLKVLVLEkEDDVAQESSGN 47
COG1233 COG1233
Phytoene dehydrogenase-related protein [Secondary metabolites biosynthesis, transport and ...
 36-67 1.21e-07

Phytoene dehydrogenase-related protein [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 440846 [Multi-domain]  Cd Length: 491  Bit Score: 54.09  E-value: 1.21e-07
                         10        20        30
                 ....*....|....*....|....*....|..
gi 972942279  36 TTTDVVIVGGGIAGLTTAYLLSKEGHKVLLLE 67
Cdd:COG1233    2 MMYDVVVIGAGIGGLAAAALLARAGYRVTVLE 33
NAD_binding_8 pfam13450
NAD(P)-binding Rossmann-like domain;
42-67 1.46e-07

NAD(P)-binding Rossmann-like domain;


Pssm-ID: 433218 [Multi-domain]  Cd Length: 67  Bit Score: 48.30  E-value: 1.46e-07
                          10        20
                  ....*....|....*....|....*.
gi 972942279   42 IVGGGIAGLTTAYLLSKEGHKVLLLE 67
Cdd:pfam13450   1 IVGAGLAGLVAAALLAKRGFRVLVLE 26
UbiH COG0654
2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases [Coenzyme ...
 36-178 1.61e-07

2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases [Coenzyme transport and metabolism, Energy production and conversion]; 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases is part of the Pathway/BioSystem: Ubiquinone biosynthesis


Pssm-ID: 440419 [Multi-domain]  Cd Length: 326  Bit Score: 53.02  E-value: 1.61e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 972942279  36 TTTDVVIVGGGIAGLTTAYLLSKEGHKVLLLEDgelASGESGRTTAHlsyALDDRyaTLEnLFGREGAQLAAESHASAID 115
Cdd:COG0654    2 MRTDVLIVGGGPAGLALALALARAGIRVTVVER---APPPRPDGRGI---ALSPR--SLE-LLRRLGLWDRLLARGAPIR 72

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 972942279 116 KIEqIVQAE------QIDCDFTRLDGFLFLHADGTHQELMEERDAAHraglpaVEWLPNAGTTGFEPGE 178
Cdd:COG0654   73 GIR-VRDGSdgrvlaRFDAAETGLPAGLVVPRADLERALLEAARALG------VELRFGTEVTGLEQDA 134
NirD COG2146
Ferredoxin subunit of nitrite reductase or a ring-hydroxylating dioxygenase [Inorganic ion ...
 442-523 2.45e-07

Ferredoxin subunit of nitrite reductase or a ring-hydroxylating dioxygenase [Inorganic ion transport and metabolism, Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 441749 [Multi-domain]  Cd Length: 103  Bit Score: 49.07  E-value: 2.45e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 972942279 442 DVSTVEEIPNGSGAVMRRGITKVAVYKDEkGAVHECSAICPHLHCVVHWNGLEKSW-DCPCHGSRF---TalGELLSGPA 517
Cdd:COG2146    5 KVCALDDLPEGGGVVVEVGGKQIAVFRTD-GEVYAYDNRCPHQGAPLSEGIVDGGVvTCPLHGARFdlrT--GECLGGPA 81


                 ....*.
gi 972942279 518 NTGLAP 523
Cdd:COG2146   82 TEPLKT 87
Rieske_proteo TIGR01416
ubiquinol-cytochrome c reductase, iron-sulfur subunit; This model represents the ...
 479-522 4.91e-07

ubiquinol-cytochrome c reductase, iron-sulfur subunit; This model represents the Proteobacterial and mitochondrial type of the Rieske [2Fe-2S] iron-sulfur as found in ubiquinol-cytochrome c reductase. The model excludes the Rieske iron-sulfur protein as found in the cytochrome b6-f complex of the Cyanobacteria and chloroplasts. Most members of this family have a recognizable twin-arginine translocation (tat) signal sequence (DeltaPh-dependent translocation in chloroplast) for transport across the membrane with the 2Fe-2S group already bound. These signal sequences include a motif resembling RRxFLK before the transmembrane helix. [Energy metabolism, Electron transport]


Pssm-ID: 273610 [Multi-domain]  Cd Length: 174  Bit Score: 49.69  E-value: 4.91e-07
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*..
gi 972942279  479 AICPHLHCVVHWNGLEKS---WDCPCHGSRFTALGELLSGPANTGLA 522
Cdd:TIGR01416 113 GICTHLGCIPTYGPEEGDkggFFCPCHGSHYDTAGRVRKGPAPLNLP 159
Rieske_cytochrome_bc1 cd03470
Iron-sulfur protein (ISP) component of the bc(1) complex family, Rieske domain; The Rieske ...
 479-522 6.76e-07

Iron-sulfur protein (ISP) component of the bc(1) complex family, Rieske domain; The Rieske domain is a [2Fe-2S] cluster binding domain involved in electron transfer. The bc(1) complex is a multisubunit enzyme found in many different organisms including uni- and multi-cellular eukaryotes, plants (in their mitochondria) and bacteria. The cytochrome bc(1) and b6f complexes are central components of the respiratory and photosynthetic electron transport chains, respectively, which carry out similar core electron and proton transfer steps. The bc(1) and b6f complexes share a common core structure of three catalytic subunits: cyt b, the Rieske ISP, and either a cyt c1 in the bc(1) complex or cyt f in the b6f complex, which are arranged in an integral membrane-bound dimeric complex. While the core of the b6f complex is similar to that of the bc(1) complex, the domain arrangement outside the core and the complement of prosthetic groups are strikingly different.


Pssm-ID: 239552  Cd Length: 126  Bit Score: 48.32  E-value: 6.76e-07
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*
gi 972942279 479 AICPHLHCV-VHWNGLEKSWDCPCHGSRFTALGELLSGPANTGLA 522
Cdd:cd03470   67 GICTHLGCVpTYRAGDYGGFFCPCHGSHYDASGRIRKGPAPLNLE 111
PLN02612 PLN02612
phytoene desaturase
 14-102 3.53e-06

phytoene desaturase


Pssm-ID: 215330 [Multi-domain]  Cd Length: 567  Bit Score: 49.46  E-value: 3.53e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 972942279  14 ATISSWFGTAPalPPFEPLaedtttDVVIVGGGIAGLTTAYLLSKEGHKVLLLE-----DGELAS-----GESGRTTAHL 83
Cdd:PLN02612  78 AALSASFRSAP--RPAKPL------KVVIAGAGLAGLSTAKYLADAGHKPILLEardvlGGKVAAwkdedGDWYETGLHI 149

                         90
                 ....*....|....*....
gi 972942279  84 SYAlddRYATLENLFGREG 102
Cdd:PLN02612 150 FFG---AYPNVQNLFGELG 165
HdrA COG1148
Heterodisulfide reductase, subunit A (polyferredoxin) [Energy production and conversion];
28-67 3.88e-06

Heterodisulfide reductase, subunit A (polyferredoxin) [Energy production and conversion];


Pssm-ID: 440762 [Multi-domain]  Cd Length: 563  Bit Score: 49.47  E-value: 3.88e-06
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|
gi 972942279  28 PFEPLAEDTTTDVVIVGGGIAGLTTAYLLSKEGHKVLLLE 67
Cdd:COG1148  131 PLEPIKVPVNKRALVIGGGIAGMTAALELAEQGYEVYLVE 170
PRK07233 PRK07233
hypothetical protein; Provisional
 40-91 3.94e-06

hypothetical protein; Provisional


Pssm-ID: 235977 [Multi-domain]  Cd Length: 434  Bit Score: 49.11  E-value: 3.94e-06
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....
gi 972942279  40 VVIVGGGIAGLTTAYLLSKEGHKVLLLEdgelASGESGRTTAHLSYALD--DRY 91
Cdd:PRK07233   2 IAIVGGGIAGLAAAYRLAKRGHEVTVFE----ADDQLGGLAASFEFGGLpiERF 51
NadB COG0029
Aspartate oxidase [Coenzyme transport and metabolism]; Aspartate oxidase is part of the ...
 34-74 4.56e-06

Aspartate oxidase [Coenzyme transport and metabolism]; Aspartate oxidase is part of the Pathway/BioSystem: NAD biosynthesis


Pssm-ID: 439800 [Multi-domain]  Cd Length: 521  Bit Score: 49.33  E-value: 4.56e-06
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|.
gi 972942279  34 EDTTTDVVIVGGGIAGLTTAYLLSKEGhKVLLLEDGELASG 74
Cdd:COG0029    1 ERLKTDVLVIGSGIAGLSAALKLAERG-RVTLLTKGELGES 40
COG3380 COG3380
Predicted NAD/FAD-dependent oxidoreductase [General function prediction only];
36-67 5.88e-06

Predicted NAD/FAD-dependent oxidoreductase [General function prediction only];


Pssm-ID: 442607 [Multi-domain]  Cd Length: 331  Bit Score: 48.34  E-value: 5.88e-06
                         10        20        30
                 ....*....|....*....|....*....|..
gi 972942279  36 TTTDVVIVGGGIAGLTTAYLLSKEGHKVLLLE 67
Cdd:COG3380    2 SMPDIAIIGAGIAGLAAARALQDAGHEVTVFE 33
PRK12771 PRK12771
putative glutamate synthase (NADPH) small subunit; Provisional
 28-74 6.36e-06

putative glutamate synthase (NADPH) small subunit; Provisional


Pssm-ID: 237198 [Multi-domain]  Cd Length: 564  Bit Score: 48.72  E-value: 6.36e-06
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*..
gi 972942279  28 PFEPLAEDTTTDVVIVGGGIAGLTTAYLLSKEGHKVLLLEDGELASG 74
Cdd:PRK12771 128 KFPAPAPDTGKRVAVIGGGPAGLSAAYHLRRMGHAVTIFEAGPKLGG 174
PRK07364 PRK07364
FAD-dependent hydroxylase;
22-67 7.63e-06

FAD-dependent hydroxylase;


Pssm-ID: 236001 [Multi-domain]  Cd Length: 415  Bit Score: 48.48  E-value: 7.63e-06
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*..
gi 972942279  22 TAPALPPFEPLAEDT-TTDVVIVGGGIAGLTTAYLLSKEGHKVLLLE 67
Cdd:PRK07364   2 TLTAATSPTLPSTRSlTYDVAIVGGGIVGLTLAAALKDSGLRIALIE 48
GG-red-SF TIGR02032
geranylgeranyl reductase family; This model represents a subfamily which includes ...
 39-71 8.23e-06

geranylgeranyl reductase family; This model represents a subfamily which includes geranylgeranyl reductases involved in chlorophyll and bacteriochlorophyll biosynthesis as well as other related enzymes which may also act on geranylgeranyl groups or related substrates. [Biosynthesis of cofactors, prosthetic groups, and carriers, Chlorophyll and bacteriochlorphyll]


Pssm-ID: 273936 [Multi-domain]  Cd Length: 295  Bit Score: 47.70  E-value: 8.23e-06
                          10        20        30
                  ....*....|....*....|....*....|...
gi 972942279   39 DVVIVGGGIAGLTTAYLLSKEGHKVLLLEDGEL 71
Cdd:TIGR02032   2 DVVVVGAGPAGASAAYRLADKGLRVLLLEKKSF 34
COG3349 COG3349
Uncharacterized protein, contains NAD-binding domain and a Fe-S cluster [General function ...
 36-67 1.12e-05

Uncharacterized protein, contains NAD-binding domain and a Fe-S cluster [General function prediction only];


Pssm-ID: 442577 [Multi-domain]  Cd Length: 445  Bit Score: 47.93  E-value: 1.12e-05
                         10        20        30
                 ....*....|....*....|....*....|..
gi 972942279  36 TTTDVVIVGGGIAGLTTAYLLSKEGHKVLLLE 67
Cdd:COG3349    2 MPPRVVVVGGGLAGLAAAVELAEAGFRVTLLE 33
BetA COG2303
Choline dehydrogenase or related flavoprotein [Lipid transport and metabolism, General ...
 35-105 1.57e-05

Choline dehydrogenase or related flavoprotein [Lipid transport and metabolism, General function prediction only]; Choline dehydrogenase or related flavoprotein is part of the Pathway/BioSystem: Non-phosphorylated Entner-Doudoroff pathway


Pssm-ID: 441878 [Multi-domain]  Cd Length: 531  Bit Score: 47.52  E-value: 1.57e-05
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 972942279  35 DTTTDVVIVGGGIAGLTTAYLLSK-EGHKVLLLEDGELASGESGRTTAHLSYALDD-----RYATL--ENLFGREGAQL 105
Cdd:COG2303    2 LEEYDYVIVGAGSAGCVLANRLSEdAGLRVLLLEAGGRDDDPLIRMPAGYAKLLGNprydwRYETEpqPGLNGRRLYWP 80
PTZ00367 PTZ00367
squalene epoxidase; Provisional
 29-67 1.88e-05

squalene epoxidase; Provisional


Pssm-ID: 240384 [Multi-domain]  Cd Length: 567  Bit Score: 47.15  E-value: 1.88e-05
                         10        20        30
                 ....*....|....*....|....*....|....*....
gi 972942279  29 FEPLAEDTTTDVVIVGGGIAGLTTAYLLSKEGHKVLLLE 67
Cdd:PTZ00367  25 FKPARTNYDYDVIIVGGSIAGPVLAKALSKQGRKVLMLE 63
SdhA COG1053
Succinate dehydrogenase/fumarate reductase, flavoprotein subunit [Energy production and ...
 35-67 2.16e-05

Succinate dehydrogenase/fumarate reductase, flavoprotein subunit [Energy production and conversion]; Succinate dehydrogenase/fumarate reductase, flavoprotein subunit is part of the Pathway/BioSystem: TCA cycle


Pssm-ID: 440673 [Multi-domain]  Cd Length: 443  Bit Score: 46.75  E-value: 2.16e-05
                         10        20        30
                 ....*....|....*....|....*....|...
gi 972942279  35 DTTTDVVIVGGGIAGLTTAYLLSKEGHKVLLLE 67
Cdd:COG1053    1 DHEYDVVVVGSGGAGLRAALEAAEAGLKVLVLE 33
mnmC PRK01747
bifunctional tRNA (5-methylaminomethyl-2-thiouridine)(34)-methyltransferase MnmD/FAD-dependent ...
 22-241 2.17e-05

bifunctional tRNA (5-methylaminomethyl-2-thiouridine)(34)-methyltransferase MnmD/FAD-dependent 5-carboxymethylaminomethyl-2-thiouridine(34) oxidoreductase MnmC;


Pssm-ID: 234978 [Multi-domain]  Cd Length: 662  Bit Score: 47.15  E-value: 2.17e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 972942279  22 TAPALPPFEPLAEDTTTDVVIVGGGIAGLTTAYLLSKEGHKVLLLE-DGELASGESG-RTTA---HLS------------ 84
Cdd:PRK01747 245 APLAAPWFARPGSPKARDAAIIGGGIAGAALALALARRGWQVTLYEaDEAPAQGASGnRQGAlypLLSkddnalsrffra 324

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 972942279  85 ---YALdDRYATLENL---FGREG---AQLaAESHASAiDKIEQIVQAeqidcdftrldgflFLHADgtHQELMEERDAA 155
Cdd:PRK01747 325 aflFAR-RFYDALPAAgvaFDHDWcgvLQL-AWDEKSA-EKIAKMLAL--------------GLPAE--LARALDAEEAE 385

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 972942279 156 HRAGLPavewLPNAGTTgFEPGECLrWPgqgqfhilkylAGLTQA-IVLQGGRICTRTHVsEV----HGGPHAHIVTEDG 230
Cdd:PRK01747 386 ELAGLP----VPCGGIF-YPQGGWL-CP-----------AELCRAlLALAGQQLTIHFGH-EVarleREDDGWQLDFAGG 447

                        250
                 ....*....|.
gi 972942279 231 TVARAkrAIVV 241
Cdd:PRK01747 448 TLASA--PVVV 456
FAD_binding_2 pfam00890
FAD binding domain; This family includes members that bind FAD. This family includes the ...
 39-76 2.21e-05

FAD binding domain; This family includes members that bind FAD. This family includes the flavoprotein subunits from succinate and fumarate dehydrogenase, aspartate oxidase and the alpha subunit of adenylylsulphate reductase.


Pssm-ID: 395718 [Multi-domain]  Cd Length: 398  Bit Score: 46.90  E-value: 2.21e-05
                          10        20        30
                  ....*....|....*....|....*....|....*...
gi 972942279   39 DVVIVGGGIAGLTTAYLLSKEGHKVLLLEDGELASGES 76
Cdd:pfam00890   1 DVLVIGGGLAGLAAALAAAEAGLKVAVVEKGQPFGGAT 38
TrxB COG0492
Thioredoxin reductase [Posttranslational modification, protein turnover, chaperones];
38-71 2.48e-05

Thioredoxin reductase [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440258 [Multi-domain]  Cd Length: 305  Bit Score: 46.27  E-value: 2.48e-05
                         10        20        30
                 ....*....|....*....|....*....|....
gi 972942279  38 TDVVIVGGGIAGLTTAYLLSKEGHKVLLLEDGEL 71
Cdd:COG0492    1 YDVVIIGAGPAGLTAAIYAARAGLKTLVIEGGEP 34
CzcO COG2072
Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD [Inorganic ...
 33-70 2.67e-05

Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD [Inorganic ion transport and metabolism];


Pssm-ID: 441675 [Multi-domain]  Cd Length: 414  Bit Score: 46.39  E-value: 2.67e-05
                         10        20        30
                 ....*....|....*....|....*....|....*...
gi 972942279  33 AEDTTTDVVIVGGGIAGLTTAYLLSKEGHKVLLLEDGE 70
Cdd:COG2072    2 AATEHVDVVVIGAGQAGLAAAYHLRRAGIDFVVLEKAD 39
Pyr_redox_2 pfam07992
Pyridine nucleotide-disulphide oxidoreductase; This family includes both class I and class II ...
 38-129 3.76e-05

Pyridine nucleotide-disulphide oxidoreductase; This family includes both class I and class II oxidoreductases and also NADH oxidases and peroxidases. This domain is actually a small NADH binding domain within a larger FAD binding domain.


Pssm-ID: 400379 [Multi-domain]  Cd Length: 301  Bit Score: 45.77  E-value: 3.76e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 972942279   38 TDVVIVGGGIAGLTTAYLLSKEGHKVLLLEDGELASG---------ESGRTTAHLSYALDDRYATLENLFGREGA--QLA 106
Cdd:pfam07992   1 YDVVVIGGGPAGLAAALTLAQLGGKVTLIEDEGTCPYggcvlskalLGAAEAPEIASLWADLYKRKEEVVKKLNNgiEVL 80

                          90       100
                  ....*....|....*....|...
gi 972942279  107 AESHASAIDKIEQIVQAEQIDCD 129
Cdd:pfam07992  81 LGTEVVSIDPGAKKVVLEELVDG 103
COG3573 COG3573
Predicted oxidoreductase [General function prediction only];
34-67 5.65e-05

Predicted oxidoreductase [General function prediction only];


Pssm-ID: 442794 [Multi-domain]  Cd Length: 551  Bit Score: 45.94  E-value: 5.65e-05
                         10        20        30
                 ....*....|....*....|....*....|....
gi 972942279  34 EDTTTDVVIVGGGIAGLTTAYLLSKEGHKVLLLE 67
Cdd:COG3573    2 AAMDADVIVVGAGLAGLVAAAELADAGRRVLLLD 35
soxA_mon TIGR01377
sarcosine oxidase, monomeric form; Sarcosine oxidase catalyzes the oxidative demethylation of ...
 39-398 5.86e-05

sarcosine oxidase, monomeric form; Sarcosine oxidase catalyzes the oxidative demethylation of sarcosine to glycine. The reaction converts tetrahydrofolate to 5,10-methylene-tetrahydrofolate. The enzyme is known in monomeric and heterotetrameric (alpha,beta,gamma,delta) forms [Energy metabolism, Amino acids and amines]


Pssm-ID: 130444 [Multi-domain]  Cd Length: 380  Bit Score: 45.59  E-value: 5.86e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 972942279   39 DVVIVGGGIAGLTTAYLLSKEGHKVLLLEDGEL------ASGESgRTTAHlSYaLDDRYATLENLFGREGAQLAAESHAS 112
Cdd:TIGR01377   2 DVIVVGAGIMGCFAAYHLAKHGKKTLLLEQFDLphsrgsSHGQS-RIIRK-AY-PEDFYTPMMLECYQLWAQLEKEAGTK 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 972942279  113 AIDKIEQIVQAEQIDCDFTRLDGFLFLHadGTHQELMEERDAAHRagLPAVEwLPNAGTTGFEpgeclrwPGQGQFHILK 192
Cdd:TIGR01377  79 LHRQTGLLLLGPKENQFLKTIQATLSRH--GLEHELLSSKQLKQR--FPNIR-VPRNEVGLLD-------PNGGVLYAEK 146

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 972942279  193 YLAGLTQAIVLQGGRICTRTHVSEVHGGPHAHIVTEDGTVARAKRAIVVAtnTPFNDRVV----MHTKQHPYRTYVVGAR 268
Cdd:TIGR01377 147 ALRALQELAEAHGATVRDGTKVVEIEPTELLVTVKTTKGSYQANKLVVTA--GAWTSKLLsplgIEIPLQPLRINVCYWR 224

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 972942279  269 VPKGSVTK------ALYWDMADPYHYvrlqevsAGPRGGqtdYDLLIVGGEDHktGQADDPS----------AHLRCLEE 332
Cdd:TIGR01377 225 EKEPGSYGvsqafpCFLVLGLNPHIY-------GLPSFE---YPGLMKVYYHH--GQQIDPDerdcpfgadiEDVQILRK 292

                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 972942279  333 WTRDRFPmvrdfeyrwsGQVMEPTDGLGYAGRNPLDA----------DNVFIITGDSGHGMthgTLGPmVVADLLA 398
Cdd:TIGR01377 293 FVRDHLP----------GLNGEPKKGEVCMYTNTPDEhfvidlhpkyDNVVIGAGFSGHGF---KLAP-VVGKILA 354
PRK07494 PRK07494
UbiH/UbiF family hydroxylase;
32-88 7.93e-05

UbiH/UbiF family hydroxylase;


Pssm-ID: 181001 [Multi-domain]  Cd Length: 388  Bit Score: 44.89  E-value: 7.93e-05
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 972942279  32 LAEDTTTDVVIVGGGIAGLTTAYLLSKEGHKVLLLeDGELASGEsGRTTAHLSYALD 88
Cdd:PRK07494   2 LMEKEHTDIAVIGGGPAGLAAAIALARAGASVALV-APEPPYAD-LRTTALLGPSIR 56
PRK07208 PRK07208
hypothetical protein; Provisional
 38-67 8.91e-05

hypothetical protein; Provisional


Pssm-ID: 235967 [Multi-domain]  Cd Length: 479  Bit Score: 44.88  E-value: 8.91e-05
                         10        20        30
                 ....*....|....*....|....*....|
gi 972942279  38 TDVVIVGGGIAGLTTAYLLSKEGHKVLLLE 67
Cdd:PRK07208   5 KSVVIIGAGPAGLTAAYELLKRGYPVTVLE 34
PRK06185 PRK06185
FAD-dependent oxidoreductase;
33-67 1.08e-04

FAD-dependent oxidoreductase;


Pssm-ID: 235729 [Multi-domain]  Cd Length: 407  Bit Score: 44.46  E-value: 1.08e-04
                         10        20        30
                 ....*....|....*....|....*....|....*
gi 972942279  33 AEDTTTDVVIVGGGIAGLTTAYLLSKEGHKVLLLE 67
Cdd:PRK06185   2 AEVETTDCCIVGGGPAGMMLGLLLARAGVDVTVLE 36
PRK12814 PRK12814
putative NADPH-dependent glutamate synthase small subunit; Provisional
 31-74 1.26e-04

putative NADPH-dependent glutamate synthase small subunit; Provisional


Pssm-ID: 139246 [Multi-domain]  Cd Length: 652  Bit Score: 44.72  E-value: 1.26e-04
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....
gi 972942279  31 PLAEDTTTDVVIVGGGIAGLTTAYLLSKEGHKVLLLEDGELASG 74
Cdd:PRK12814 187 ERAPKSGKKVAIIGAGPAGLTAAYYLLRKGHDVTIFDANEQAGG 230
PRK12843 PRK12843
FAD-dependent oxidoreductase;
22-81 2.38e-04

FAD-dependent oxidoreductase;


Pssm-ID: 237225 [Multi-domain]  Cd Length: 578  Bit Score: 43.96  E-value: 2.38e-04
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 972942279  22 TAPALPPFEPLAEDTTTDVVIVGGGIAGLTTAYLLSKEGHKVLLLEDGELASGesgrTTA 81
Cdd:PRK12843   1 MSPVVSELSPERWDAEFDVIVIGAGAAGMSAALFAAIAGLKVLLVERTEYVGG----TTA 56
Ppro0129 COG2907
Predicted flavin-containing amine oxidase [General function prediction only];
42-67 2.72e-04

Predicted flavin-containing amine oxidase [General function prediction only];


Pssm-ID: 442151 [Multi-domain]  Cd Length: 423  Bit Score: 43.57  E-value: 2.72e-04
                         10        20
                 ....*....|....*....|....*.
gi 972942279  42 IVGGGIAGLTTAYLLSKEgHKVLLLE 67
Cdd:COG2907    8 VIGSGISGLTAAWLLSRR-HDVTLFE 32
Thi4 pfam01946
Thi4 family; This family includes Swiss:P32318 a putative thiamine biosynthetic enzyme.
 29-67 2.86e-04

Thi4 family; This family includes Swiss:P32318 a putative thiamine biosynthetic enzyme.


Pssm-ID: 460393  Cd Length: 232  Bit Score: 42.46  E-value: 2.86e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|
gi 972942279   29 FEPLAEDTTTDVVIVGGGIAGLTTAYLLSKE-GHKVLLLE 67
Cdd:pfam01946   9 FEDLDDYAESDVVIVGAGSSGLTAAYYLAKNrGLKVAIIE 48
PRK07804 PRK07804
L-aspartate oxidase; Provisional
 36-74 3.63e-04

L-aspartate oxidase; Provisional


Pssm-ID: 236102 [Multi-domain]  Cd Length: 541  Bit Score: 43.04  E-value: 3.63e-04
                         10        20        30
                 ....*....|....*....|....*....|....*....
gi 972942279  36 TTTDVVIVGGGIAGLTTAYLLSKEGHKVLLLEDGELASG 74
Cdd:PRK07804  15 DAADVVVVGSGVAGLTAALAARRAGRRVLVVTKAALDDG 53
Rieske_ArOX_small cd03476
Small subunit of Arsenite oxidase (ArOX) family, Rieske domain; ArOX is a molybdenum/iron ...
 478-521 3.71e-04

Small subunit of Arsenite oxidase (ArOX) family, Rieske domain; ArOX is a molybdenum/iron protein involved in the detoxification of arsenic, oxidizing it to arsenate. It consists of two subunits, a large subunit similar to members of the DMSO reductase family of molybdenum enzymes and a small subunit with a Rieske-type [2Fe-2S] cluster. The large subunit of ArOX contains the molybdenum site at which the oxidation of arsenite occurs. The small subunit contains a domain homologous to the Rieske domains of the cytochrome bc(1) and cytochrome b6f complexes as well as naphthalene 1,2-dioxygenase. The Rieske domain is a [2Fe-2S] cluster binding domain involved in electron transfer.


Pssm-ID: 239558  Cd Length: 126  Bit Score: 40.45  E-value: 3.71e-04
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*.
gi 972942279 478 SAICPHLHCVVHWNGLEKSWDCPCHGSRF--TALGELLSGPANTGL 521
Cdd:cd03476   52 SALCTHMGCPLTYDPSNKTFVCPCHFSQFdpARGGQMVSGQATQNL 97
PRK08163 PRK08163
3-hydroxybenzoate 6-monooxygenase;
35-74 4.07e-04

3-hydroxybenzoate 6-monooxygenase;


Pssm-ID: 181262 [Multi-domain]  Cd Length: 396  Bit Score: 42.72  E-value: 4.07e-04
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....
gi 972942279  35 DTTTDVVIVGGGIAGLTTAYLLSKEGHKVLLLED----GELASG 74
Cdd:PRK08163   2 TKVTPVLIVGGGIGGLAAALALARQGIKVKLLEQaaeiGEIGAG 45
PLN03000 PLN03000
amine oxidase
 20-110 4.78e-04

amine oxidase


Pssm-ID: 178578 [Multi-domain]  Cd Length: 881  Bit Score: 43.08  E-value: 4.78e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 972942279  20 FGTAPALPPFEPlAEDTTTDVVIVGGGIAGLTTAYLLSKEGHKVLLLEDGELASG-------ESGRTTAHLSYALDDRYA 92
Cdd:PLN03000 168 FGIAQAIKDKFP-AQSSKSSVVIVGAGLSGLAAARQLMRFGFKVTVLEGRKRPGGrvytkkmEANRVGAAADLGGSVLTG 246

                         90
                 ....*....|....*...
gi 972942279  93 TLENLFGREGAQLAAESH 110
Cdd:PLN03000 247 TLGNPLGIIARQLGSSLY 264
PRK10015 PRK10015
oxidoreductase; Provisional
 35-115 4.91e-04

oxidoreductase; Provisional


Pssm-ID: 182194 [Multi-domain]  Cd Length: 429  Bit Score: 42.66  E-value: 4.91e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 972942279  35 DTTTDVVIVGGGIAGLTTAYLLSKEGHKVLLLEDGELASGES---GRTTAHLSYALDDRYAT---LENLFGREGAQLAAE 108
Cdd:PRK10015   3 DDKFDAIVVGAGVAGSVAALVMARAGLDVLVIERGDSAGCKNmtgGRLYAHTLEAIIPGFAAsapVERKVTREKISFLTE 82


                 ....*..
gi 972942279 109 SHASAID 115
Cdd:PRK10015  83 ESAVTLD 89
mhpA PRK06183
bifunctional 3-(3-hydroxy-phenyl)propionate/3-hydroxycinnamic acid hydroxylase;
31-67 5.23e-04

bifunctional 3-(3-hydroxy-phenyl)propionate/3-hydroxycinnamic acid hydroxylase;


Pssm-ID: 235727 [Multi-domain]  Cd Length: 500  Bit Score: 42.59  E-value: 5.23e-04
                         10        20        30
                 ....*....|....*....|....*....|....*..
gi 972942279  31 PLAEDTTTDVVIVGGGIAGLTTAYLLSKEGHKVLLLE 67
Cdd:PRK06183   4 QHPDAHDTDVVIVGAGPVGLTLANLLGQYGVRVLVLE 40
PRK10157 PRK10157
putative oxidoreductase FixC; Provisional
 39-115 5.36e-04

putative oxidoreductase FixC; Provisional


Pssm-ID: 182273 [Multi-domain]  Cd Length: 428  Bit Score: 42.59  E-value: 5.36e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 972942279  39 DVVIVGGGIAGLTTAYLLSKEGHKVLLLEDGELASGES---GRTTAH-LSYALDD--RYATLENLFGREGAQLAAESHAS 112
Cdd:PRK10157   7 DAIIVGAGLAGSVAALVLAREGAQVLVIERGNSAGAKNvtgGRLYAHsLEHIIPGfaDSAPVERLITHEKLAFMTEKSAM 86


                 ...
gi 972942279 113 AID 115
Cdd:PRK10157  87 TMD 89
PRK12409 PRK12409
D-amino acid dehydrogenase small subunit; Provisional
 38-107 5.50e-04

D-amino acid dehydrogenase small subunit; Provisional


Pssm-ID: 237093 [Multi-domain]  Cd Length: 410  Bit Score: 42.32  E-value: 5.50e-04
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 972942279  38 TDVVIVGGGIAGLTTAYLLSKEGHKVLLLEdgelasgesgrttahlsyalDDRYATLENLFGrEGAQLAA 107
Cdd:PRK12409   2 SHIAVIGAGITGVTTAYALAQRGYQVTVFD--------------------RHRYAAMETSFA-NGGQLSA 50
PRK00711 PRK00711
D-amino acid dehydrogenase;
40-67 6.20e-04

D-amino acid dehydrogenase;


Pssm-ID: 234819 [Multi-domain]  Cd Length: 416  Bit Score: 42.09  E-value: 6.20e-04
                         10        20
                 ....*....|....*....|....*...
gi 972942279  40 VVIVGGGIAGLTTAYLLSKEGHKVLLLE 67
Cdd:PRK00711   3 VVVLGSGVIGVTSAWYLAQAGHEVTVID 30
PLN02576 PLN02576
protoporphyrinogen oxidase
 33-74 7.09e-04

protoporphyrinogen oxidase


Pssm-ID: 215314 [Multi-domain]  Cd Length: 496  Bit Score: 42.31  E-value: 7.09e-04
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|...
gi 972942279  33 AEDTTTDVVIVGGGIAGLTTAY-LLSKEGHKVLLLEDGELASG 74
Cdd:PLN02576   8 AAASSKDVAVVGAGVSGLAAAYaLASKHGVNVLVTEARDRVGG 50
PRK06753 PRK06753
hypothetical protein; Provisional
 40-67 7.67e-04

hypothetical protein; Provisional


Pssm-ID: 168661 [Multi-domain]  Cd Length: 373  Bit Score: 41.98  E-value: 7.67e-04
                         10        20
                 ....*....|....*....|....*...
gi 972942279  40 VVIVGGGIAGLTTAYLLSKEGHKVLLLE 67
Cdd:PRK06753   3 IAIIGAGIGGLTAAALLQEQGHEVKVFE 30
PRK12834 PRK12834
putative FAD-binding dehydrogenase; Reviewed
 34-67 8.22e-04

putative FAD-binding dehydrogenase; Reviewed


Pssm-ID: 183782 [Multi-domain]  Cd Length: 549  Bit Score: 42.19  E-value: 8.22e-04
                         10        20        30
                 ....*....|....*....|....*....|....
gi 972942279  34 EDTTTDVVIVGGGIAGLTTAYLLSKEGHKVLLLE 67
Cdd:PRK12834   1 MAMDADVIVVGAGLAGLVAAAELADAGKRVLLLD 34
PRK06292 PRK06292
dihydrolipoamide dehydrogenase; Validated
 37-71 9.08e-04

dihydrolipoamide dehydrogenase; Validated


Pssm-ID: 235774 [Multi-domain]  Cd Length: 460  Bit Score: 41.70  E-value: 9.08e-04
                         10        20        30
                 ....*....|....*....|....*....|....*
gi 972942279  37 TTDVVIVGGGIAGLTTAYLLSKEGHKVLLLEDGEL 71
Cdd:PRK06292   3 KYDVIVIGAGPAGYVAARRAAKLGKKVALIEKGPL 37
PLN02661 PLN02661
Putative thiazole synthesis
 38-83 1.03e-03

Putative thiazole synthesis


Pssm-ID: 178267  Cd Length: 357  Bit Score: 41.35  E-value: 1.03e-03
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 972942279  38 TDVVIVGGGIAGLTTAYLLSKEGH-KVLLLED-----------GELASGESGRTTAHL 83
Cdd:PLN02661  93 TDVVIVGAGSAGLSCAYELSKNPNvKVAIIEQsvspgggawlgGQLFSAMVVRKPAHL 150
PRK06847 PRK06847
hypothetical protein; Provisional
 39-67 1.05e-03

hypothetical protein; Provisional


Pssm-ID: 235874 [Multi-domain]  Cd Length: 375  Bit Score: 41.40  E-value: 1.05e-03
                         10        20
                 ....*....|....*....|....*....
gi 972942279  39 DVVIVGGGIAGLTTAYLLSKEGHKVLLLE 67
Cdd:PRK06847   6 KVLIVGGGIGGLSAAIALRRAGIAVDLVE 34
glpA PRK11101
anaerobic glycerol-3-phosphate dehydrogenase subunit A;
36-90 1.15e-03

anaerobic glycerol-3-phosphate dehydrogenase subunit A;


Pssm-ID: 236847 [Multi-domain]  Cd Length: 546  Bit Score: 41.54  E-value: 1.15e-03
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 972942279  36 TTTDVVIVGGGIAGLTTAYLLSKEGHKVLLLEDGELASGESGRTTAHL----SYALDDR 90
Cdd:PRK11101   5 QETDVIIIGGGATGAGIARDCALRGLRCILVERHDIATGATGRNHGLLhsgaRYAVTDA 63
GltD COG0493
NADPH-dependent glutamate synthase beta chain or related oxidoreductase [Amino acid transport ...
 27-63 1.19e-03

NADPH-dependent glutamate synthase beta chain or related oxidoreductase [Amino acid transport and metabolism, General function prediction only]; NADPH-dependent glutamate synthase beta chain or related oxidoreductase is part of the Pathway/BioSystem: Glutamine biosynthesis


Pssm-ID: 440259 [Multi-domain]  Cd Length: 434  Bit Score: 41.27  E-value: 1.19e-03
                         10        20        30
                 ....*....|....*....|....*....|....*..
gi 972942279  27 PPFEPlAEDTTTDVVIVGGGIAGLTTAYLLSKEGHKV 63
Cdd:COG0493  112 KPPPP-APRTGKKVAVVGSGPAGLAAAYQLARAGHEV 147
PLN02985 PLN02985
squalene monooxygenase
 34-67 1.38e-03

squalene monooxygenase


Pssm-ID: 178566 [Multi-domain]  Cd Length: 514  Bit Score: 41.43  E-value: 1.38e-03
                         10        20        30
                 ....*....|....*....|....*....|....
gi 972942279  34 EDTTTDVVIVGGGIAGLTTAYLLSKEGHKVLLLE 67
Cdd:PLN02985  40 KDGATDVIIVGAGVGGSALAYALAKDGRRVHVIE 73
FixC COG0644
Dehydrogenase (flavoprotein) [Energy production and conversion];
45-67 1.38e-03

Dehydrogenase (flavoprotein) [Energy production and conversion];


Pssm-ID: 440409 [Multi-domain]  Cd Length: 281  Bit Score: 40.72  E-value: 1.38e-03
                         10        20
                 ....*....|....*....|...
gi 972942279  45 GGIAGLTTAYLLSKEGHKVLLLE 67
Cdd:COG0644    1 AGPAGSAAARRLARAGLSVLLLE 23
GlpB COG3075
Anaerobic glycerol-3-phosphate dehydrogenase [Amino acid transport and metabolism];
37-74 1.54e-03

Anaerobic glycerol-3-phosphate dehydrogenase [Amino acid transport and metabolism];


Pssm-ID: 442309  Cd Length: 415  Bit Score: 40.93  E-value: 1.54e-03
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|..
gi 972942279  37 TTDVVIVGGGIAGLTTAYLLSKEGHKVLLLEDGE----LASG 74
Cdd:COG3075    2 KFDVVVIGGGLAGLTAAIRAAEAGLRVAIVSAGQsalhFSSG 43
proto_IX_ox TIGR00562
protoporphyrinogen oxidase; This enzyme oxidizes protoporphyrinogen IX to protoporphyrin IX, a ...
 37-59 1.67e-03

protoporphyrinogen oxidase; This enzyme oxidizes protoporphyrinogen IX to protoporphyrin IX, a precursor of heme and chlorophyll. Bacillus subtilis HemY also has coproporphyrinogen III to coproporphyrin III oxidase activity in a heterologous expression system, although the role for this activity in vivo is unclear. This protein is a flavoprotein and has a beta-alpha-beta dinucleotide binding motif near the amino end. [Biosynthesis of cofactors, prosthetic groups, and carriers, Heme, porphyrin, and cobalamin]


Pssm-ID: 213540 [Multi-domain]  Cd Length: 462  Bit Score: 40.97  E-value: 1.67e-03
                          10        20
                  ....*....|....*....|...
gi 972942279   37 TTDVVIVGGGIAGLTTAYLLSKE 59
Cdd:TIGR00562   2 KKHVVIIGGGISGLCAAYYLEKE 24
Rieske_RO_Alpha_N cd03469
Rieske non-heme iron oxygenase (RO) family, N-terminal Rieske domain of the oxygenase alpha ...
 443-520 2.16e-03

Rieske non-heme iron oxygenase (RO) family, N-terminal Rieske domain of the oxygenase alpha subunit; The RO family comprise a large class of aromatic ring-hydroxylating dioxygenases found predominantly in microorganisms. These enzymes enable microorganisms to tolerate and even exclusively utilize aromatic compounds for growth. ROs consist of two or three components: reductase, oxygenase, and ferredoxin (in some cases) components. The oxygenase component may contain alpha and beta subunits, with the beta subunit having a purely structural function. Some oxygenase components contain only an alpha subunit. The oxygenase alpha subunit has two domains, an N-terminal Rieske domain with an [2Fe-2S] cluster and a C-terminal catalytic domain with a mononuclear Fe(II) binding site. The Rieske [2Fe-2S] cluster accepts electrons from the reductase or ferredoxin component and transfers them to the mononuclear iron for catalysis. Reduced pyridine nucleotide is used as the initial source of two electrons for dioxygen activation.


Pssm-ID: 239551 [Multi-domain]  Cd Length: 118  Bit Score: 37.95  E-value: 2.16e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 972942279 443 VSTVEEIPN-GSGAVMRRGITKVAVYKDEKGAVHECSAICPHLHC--VVHWNGLEKSWDCPCHGSRFTALGELLSGPANT 519
Cdd:cd03469    4 VGHSSELPEpGDYVTLELGGEPLVLVRDRDGEVRAFHNVCPHRGArlCEGRGGNAGRLVCPYHGWTYDLDGKLVGVPREE 83


                 .
gi 972942279 520 G 520
Cdd:cd03469   84 G 84
PRK05329 PRK05329
glycerol-3-phosphate dehydrogenase subunit GlpB;
39-74 2.58e-03

glycerol-3-phosphate dehydrogenase subunit GlpB;


Pssm-ID: 235412  Cd Length: 422  Bit Score: 40.22  E-value: 2.58e-03
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|
gi 972942279  39 DVVIVGGGIAGLTTAYLLSKEGHKVLLLEDGE----LASG 74
Cdd:PRK05329   4 DVLVIGGGLAGLTAALAAAEAGKRVALVAKGQgalhFSSG 43
FAD_binding_3 pfam01494
FAD binding domain; This domain is involved in FAD binding in a number of enzymes.
 38-67 3.74e-03

FAD binding domain; This domain is involved in FAD binding in a number of enzymes.


Pssm-ID: 396193 [Multi-domain]  Cd Length: 348  Bit Score: 39.62  E-value: 3.74e-03
                          10        20        30
                  ....*....|....*....|....*....|
gi 972942279   38 TDVVIVGGGIAGLTTAYLLSKEGHKVLLLE 67
Cdd:pfam01494   2 TDVLIVGGGPAGLMLALLLARAGVRVVLVE 31
PRK08132 PRK08132
FAD-dependent oxidoreductase; Provisional
 28-68 3.97e-03

FAD-dependent oxidoreductase; Provisional


Pssm-ID: 236158 [Multi-domain]  Cd Length: 547  Bit Score: 39.85  E-value: 3.97e-03
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*.
gi 972942279  28 PFEPLAEDTTTD-----VVIVGGGIAGLTTAYLLSKEGHKVLLLED 68
Cdd:PRK08132   9 PYRPHADQDADDparhpVVVVGAGPVGLALAIDLAQQGVPVVLLDD 54
HI0933_like pfam03486
HI0933-like protein;
38-69 4.34e-03

HI0933-like protein;


Pssm-ID: 427330 [Multi-domain]  Cd Length: 406  Bit Score: 39.49  E-value: 4.34e-03
                          10        20        30
                  ....*....|....*....|....*....|..
gi 972942279   38 TDVVIVGGGIAGLTTAYLLSKEGHKVLLLEDG 69
Cdd:pfam03486   1 FDVIVIGGGAAGLMAAISAAKRGRRVLLIEKG 32
PLN02529 PLN02529
lysine-specific histone demethylase 1
 20-67 4.49e-03

lysine-specific histone demethylase 1


Pssm-ID: 178144 [Multi-domain]  Cd Length: 738  Bit Score: 39.87  E-value: 4.49e-03
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*...
gi 972942279  20 FGTAPALPPFEPlAEDTTTDVVIVGGGIAGLTTAYLLSKEGHKVLLLE 67
Cdd:PLN02529 144 FGVSPSFASPIP-EEGTEGSVIIVGAGLAGLAAARQLLSFGFKVVVLE 190
PRK11883 PRK11883
protoporphyrinogen oxidase; Reviewed
 40-70 5.36e-03

protoporphyrinogen oxidase; Reviewed


Pssm-ID: 237009 [Multi-domain]  Cd Length: 451  Bit Score: 39.45  E-value: 5.36e-03
                         10        20        30
                 ....*....|....*....|....*....|...
gi 972942279  40 VVIVGGGIAGLTTAYLLSKEG--HKVLLLEDGE 70
Cdd:PRK11883   3 VAIIGGGITGLSAAYRLHKKGpdADITLLEASD 35
FAD_oxidored pfam12831
FAD dependent oxidoreductase; This family of proteins contains FAD dependent oxidoreductases ...
 39-69 6.93e-03

FAD dependent oxidoreductase; This family of proteins contains FAD dependent oxidoreductases and related proteins.


Pssm-ID: 432816 [Multi-domain]  Cd Length: 420  Bit Score: 38.74  E-value: 6.93e-03
                          10        20        30
                  ....*....|....*....|....*....|.
gi 972942279   39 DVVIVGGGIAGLTTAYLLSKEGHKVLLLEDG 69
Cdd:pfam12831   1 DVVVVGGGPAGVAAAIAAARAGAKVLLVERR 31
GIDA pfam01134
Glucose inhibited division protein A;
39-66 7.39e-03

Glucose inhibited division protein A;


Pssm-ID: 250388 [Multi-domain]  Cd Length: 391  Bit Score: 38.69  E-value: 7.39e-03
                          10        20
                  ....*....|....*....|....*...
gi 972942279   39 DVVIVGGGIAGLTTAYLLSKEGHKVLLL 66
Cdd:pfam01134   1 DVIVIGGGHAGCEAALAAARMGAKVLLI 28
Lpd COG1249
Dihydrolipoamide dehydrogenase (E3) component of pyruvate/2-oxoglutarate dehydrogenase complex ...
 35-71 8.07e-03

Dihydrolipoamide dehydrogenase (E3) component of pyruvate/2-oxoglutarate dehydrogenase complex or glutathione oxidoreductase [Energy production and conversion]; Dihydrolipoamide dehydrogenase (E3) component of pyruvate/2-oxoglutarate dehydrogenase complex or glutathione oxidoreductase is part of the Pathway/BioSystem: Glycine cleavagePyruvate oxidation


Pssm-ID: 440861 [Multi-domain]  Cd Length: 456  Bit Score: 38.91  E-value: 8.07e-03
                         10        20        30
                 ....*....|....*....|....*....|....*..
gi 972942279  35 DTTTDVVIVGGGIAGLTTAYLLSKEGHKVLLLEDGEL 71
Cdd:COG1249    1 MKDYDLVVIGAGPGGYVAAIRAAQLGLKVALVEKGRL 37
arsenite_ox_S TIGR02694
arsenite oxidase, small subunit; This model represents the small subunit of an arsenite ...
 478-506 9.04e-03

arsenite oxidase, small subunit; This model represents the small subunit of an arsenite oxidase complex. It is a Rieske protein and appears to rely on the Tat (twin-arginine translocation) system to cross the membrane. Although this enzyme could run in the direction of arsenate reduction to arsenite in principle, the relevant biological function is arsenite oxidation for energy metabolism, not arsenic resistance. Homologs to both large (TIGR02693) and small subunits that score in the gray zone between the set trusted and noise bit score cutoffs for the respective models are found in Aeropyrum pernix K1 and in Sulfolobus tokodaii str. 7. [Energy metabolism, Electron transport]


Pssm-ID: 131741  Cd Length: 129  Bit Score: 36.40  E-value: 9.04e-03
                          10        20
                  ....*....|....*....|....*....
gi 972942279  478 SAICPHLHCVVHWNGLEKSWDCPCHGSRF 506
Cdd:TIGR02694  55 STLCTHMGCPVSYSADNKTFNCPCHFSVF 83
YhiN COG2081
Predicted flavoprotein YhiN [General function prediction only];
41-91 9.44e-03

Predicted flavoprotein YhiN [General function prediction only];


Pssm-ID: 441684 [Multi-domain]  Cd Length: 402  Bit Score: 38.49  E-value: 9.44e-03
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 972942279  41 VIVGGGIAGLTTAYLLSKEGHKVLLLEDGE------LASGeSGR---TTAHLSYALDDRY 91
Cdd:COG2081    1 IVIGAGAAGLMAAITAAERGARVLLLEKNPkvgrkiLISG-GGRcnfTNSEPLPEFLNYY 59
glycerol3P_GlpB TIGR03378
glycerol-3-phosphate dehydrogenase, anaerobic, B subunit; Members of this protein family are ...
 39-72 9.79e-03

glycerol-3-phosphate dehydrogenase, anaerobic, B subunit; Members of this protein family are the B subunit, product of the glpB gene, of a three-subunit, membrane-anchored, FAD-dependent anaerobic glycerol-3-phosphate dehydrogenase. [Energy metabolism, Anaerobic]


Pssm-ID: 213807  Cd Length: 419  Bit Score: 38.46  E-value: 9.79e-03
                          10        20        30
                  ....*....|....*....|....*....|....
gi 972942279   39 DVVIVGGGIAGLTTAYLLSKEGHKVLLLEDGELA 72
Cdd:TIGR03378   2 DVIIIGGGLAGLSCALRLAEAGKKCAIIAAGQSA 35
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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