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Conserved domains on  [gi|971746594|ref|YP_009200610|]
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RNA polymerase inhibitor [Escherichia phage P483]

Protein Classification

PHA00457 family protein( domain architecture ID 10009713)

PHA00457 family protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PHA00457 PHA00457
inhibitor of host bacterial RNA polymerase
 1-62 3.36e-33

inhibitor of host bacterial RNA polymerase


:

Pssm-ID: 222799  Cd Length: 63  Bit Score: 108.09  E-value: 3.36e-33
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 971746594  1 MSNLNKGSLVNGDKKFFATVEGQGQSFEVPVFAVSLEEANELAEWQYVPAGFAVTRIRPDRK 62
Cdd:PHA00457  1 MSNLNKGSLVNGEKKFIATVEGSGQSFEVPVYAKSLEEATELAEWQYVPAGFVVTRIRPEVK 62
 
Name Accession Description Interval E-value
PHA00457 PHA00457
inhibitor of host bacterial RNA polymerase
 1-62 3.36e-33

inhibitor of host bacterial RNA polymerase


Pssm-ID: 222799  Cd Length: 63  Bit Score: 108.09  E-value: 3.36e-33
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 971746594  1 MSNLNKGSLVNGDKKFFATVEGQGQSFEVPVFAVSLEEANELAEWQYVPAGFAVTRIRPDRK 62
Cdd:PHA00457  1 MSNLNKGSLVNGEKKFIATVEGSGQSFEVPVYAKSLEEATELAEWQYVPAGFVVTRIRPEVK 62
RNA_pol_inhib pfam16857
RNA polymerase inhibitor; This bacteriophage protein inhibits the bacterial host RNA ...
 14-60 3.64e-24

RNA polymerase inhibitor; This bacteriophage protein inhibits the bacterial host RNA polymerase by interacting with the RpoC subunit and inhibiting the formation of a promoter complex.


Pssm-ID: 435606  Cd Length: 47  Bit Score: 84.75  E-value: 3.64e-24
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*..
gi 971746594  14 KKFFATVEGQGQSFEVPVFAVSLEEANELAEWQYVPAGFAVTRIRPD 60
Cdd:pfam16857  1 KKFIATVEGRGTSFEVPVYAESLDEALEVAEEEYEEAGFAVTRVRPE 47
 
Name Accession Description Interval E-value
PHA00457 PHA00457
inhibitor of host bacterial RNA polymerase
 1-62 3.36e-33

inhibitor of host bacterial RNA polymerase


Pssm-ID: 222799  Cd Length: 63  Bit Score: 108.09  E-value: 3.36e-33
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 971746594  1 MSNLNKGSLVNGDKKFFATVEGQGQSFEVPVFAVSLEEANELAEWQYVPAGFAVTRIRPDRK 62
Cdd:PHA00457  1 MSNLNKGSLVNGEKKFIATVEGSGQSFEVPVYAKSLEEATELAEWQYVPAGFVVTRIRPEVK 62
RNA_pol_inhib pfam16857
RNA polymerase inhibitor; This bacteriophage protein inhibits the bacterial host RNA ...
 14-60 3.64e-24

RNA polymerase inhibitor; This bacteriophage protein inhibits the bacterial host RNA polymerase by interacting with the RpoC subunit and inhibiting the formation of a promoter complex.


Pssm-ID: 435606  Cd Length: 47  Bit Score: 84.75  E-value: 3.64e-24
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*..
gi 971746594  14 KKFFATVEGQGQSFEVPVFAVSLEEANELAEWQYVPAGFAVTRIRPD 60
Cdd:pfam16857  1 KKFIATVEGRGTSFEVPVYAESLDEALEVAEEEYEEAGFAVTRVRPE 47
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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