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Conserved domains on  [gi|970962700|ref|WP_058843378|]
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MULTISPECIES: helix-turn-helix transcriptional regulator [Lysinibacillus]

Protein Classification

helix-turn-helix transcriptional regulator( domain architecture ID 12204063)

helix-turn-helix (HTH) transcriptional regulator containing an AraC family DNA-binding HTH domain controls the expression of genes with diverse biological functions including metabolism, stress response, and virulence

CATH:  1.10.10.1310
Gene Ontology:  GO:0006355|GO:0043565|GO:0003700
PubMed:  2644244|15808743|8831795
SCOP:  4000332

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
HTH_ARAC smart00342
helix_turn_helix, arabinose operon control protein;
230-313 6.83e-24

helix_turn_helix, arabinose operon control protein;


:

Pssm-ID: 197666 [Multi-domain]  Cd Length: 84  Bit Score: 93.00  E-value: 6.83e-24
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 970962700   230 QLTLDHLTKISCMGATKLKKLFKEVYHCTITEYIQKQRVHQAEKLLAHTELPINEIARKVGYQSAGRFSELFKRYLDLTP 309
Cdd:smart00342   1 PLTLEDLAEALGVSPRHLQRLFKKETGTTPKQYLRDRRLERARRLLRDTDLSVTEIALRVGFSSQSYFSRAFKKLFGVTP 80


                   ....
gi 970962700   310 KEYR 313
Cdd:smart00342  81 SEYR 84
 
Name Accession Description Interval E-value
HTH_ARAC smart00342
helix_turn_helix, arabinose operon control protein;
230-313 6.83e-24

helix_turn_helix, arabinose operon control protein;


Pssm-ID: 197666 [Multi-domain]  Cd Length: 84  Bit Score: 93.00  E-value: 6.83e-24
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 970962700   230 QLTLDHLTKISCMGATKLKKLFKEVYHCTITEYIQKQRVHQAEKLLAHTELPINEIARKVGYQSAGRFSELFKRYLDLTP 309
Cdd:smart00342   1 PLTLEDLAEALGVSPRHLQRLFKKETGTTPKQYLRDRRLERARRLLRDTDLSVTEIALRVGFSSQSYFSRAFKKLFGVTP 80


                   ....
gi 970962700   310 KEYR 313
Cdd:smart00342  81 SEYR 84
AraC COG2207
AraC-type DNA-binding domain and AraC-containing proteins [Transcription];
206-318 2.15e-22

AraC-type DNA-binding domain and AraC-containing proteins [Transcription];


Pssm-ID: 441809 [Multi-domain]  Cd Length: 258  Bit Score: 94.08  E-value: 2.15e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 970962700 206 SQISKEDIHHIEHVAAHIENYYTLQLTLDHLTKISCMGATKLKKLFKEVYHCTITEYIQKQRVHQAEKLLAHTELPINEI 285
Cdd:COG2207  144 LLLLLLLLLLLLLLLLLLLLLLLLLLTLEELARELGLSPRTLSRLFKEETGTSPKQYLRELRLERAKRLLAETDLSISEI 223

                         90       100       110
                 ....*....|....*....|....*....|...
gi 970962700 286 ARKVGYQSAGRFSELFKRYLDLTPKEYRQQLSK 318
Cdd:COG2207  224 AYELGFSSQSHFSRAFKKRFGVTPSEYRKRLRA 256
HTH_18 pfam12833
Helix-turn-helix domain;
236-315 2.27e-21

Helix-turn-helix domain;


Pssm-ID: 432818 [Multi-domain]  Cd Length: 81  Bit Score: 86.10  E-value: 2.27e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 970962700  236 LTKISCMGATKLKKLFKEVYHCTITEYIQKQRVHQAEKLLAH-TELPINEIARKVGYQSAGRFSELFKRYLDLTPKEYRQ 314
Cdd:pfam12833   1 LAAALGMSPRTLSRLFKRELGLSPKEYLRRLRLERARRLLLEdTGLSVAEIALALGFSDASHFSRAFRRLFGLTPSEYRR 80


                  .
gi 970962700  315 Q 315
Cdd:pfam12833  81 R 81
PRK10572 PRK10572
arabinose operon transcriptional regulator AraC;
150-315 1.08e-14

arabinose operon transcriptional regulator AraC;


Pssm-ID: 236717 [Multi-domain]  Cd Length: 290  Bit Score: 73.08  E-value: 1.08e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 970962700 150 TTLKATSTFSEMVILLRQIAV-YRGSDLTSalfyegkvyEALAL-IMERALsdktCHCSQISKEDIHH-----IEHVAAH 222
Cdd:PRK10572 125 LRIPDEALQPEFSDLFGQIEQaGQSEGRYS---------ELLAMnLLERLL----LRCMEAIPESLHPpmdprVREACQY 191

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 970962700 223 IENYYTLQLTLDHLTKISCMGATKLKKLFKEVYHCTITEYIQKQRVHQAEKLLAHTELPINEIARKVGYQSAGRFSELFK 302
Cdd:PRK10572 192 ISDHLASEFDIESVAQHVCLSPSRLAHLFRQQLGISVLRWREDQRISRAKLLLQTTRMPIATIGRNVGYDDQLYFSRVFK 271

                        170
                 ....*....|...
gi 970962700 303 RYLDLTPKEYRQQ 315
Cdd:PRK10572 272 KCTGASPSEFRAR 284
 
Name Accession Description Interval E-value
HTH_ARAC smart00342
helix_turn_helix, arabinose operon control protein;
230-313 6.83e-24

helix_turn_helix, arabinose operon control protein;


Pssm-ID: 197666 [Multi-domain]  Cd Length: 84  Bit Score: 93.00  E-value: 6.83e-24
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 970962700   230 QLTLDHLTKISCMGATKLKKLFKEVYHCTITEYIQKQRVHQAEKLLAHTELPINEIARKVGYQSAGRFSELFKRYLDLTP 309
Cdd:smart00342   1 PLTLEDLAEALGVSPRHLQRLFKKETGTTPKQYLRDRRLERARRLLRDTDLSVTEIALRVGFSSQSYFSRAFKKLFGVTP 80


                   ....
gi 970962700   310 KEYR 313
Cdd:smart00342  81 SEYR 84
AraC COG2207
AraC-type DNA-binding domain and AraC-containing proteins [Transcription];
206-318 2.15e-22

AraC-type DNA-binding domain and AraC-containing proteins [Transcription];


Pssm-ID: 441809 [Multi-domain]  Cd Length: 258  Bit Score: 94.08  E-value: 2.15e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 970962700 206 SQISKEDIHHIEHVAAHIENYYTLQLTLDHLTKISCMGATKLKKLFKEVYHCTITEYIQKQRVHQAEKLLAHTELPINEI 285
Cdd:COG2207  144 LLLLLLLLLLLLLLLLLLLLLLLLLLTLEELARELGLSPRTLSRLFKEETGTSPKQYLRELRLERAKRLLAETDLSISEI 223

                         90       100       110
                 ....*....|....*....|....*....|...
gi 970962700 286 ARKVGYQSAGRFSELFKRYLDLTPKEYRQQLSK 318
Cdd:COG2207  224 AYELGFSSQSHFSRAFKKRFGVTPSEYRKRLRA 256
HTH_18 pfam12833
Helix-turn-helix domain;
236-315 2.27e-21

Helix-turn-helix domain;


Pssm-ID: 432818 [Multi-domain]  Cd Length: 81  Bit Score: 86.10  E-value: 2.27e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 970962700  236 LTKISCMGATKLKKLFKEVYHCTITEYIQKQRVHQAEKLLAH-TELPINEIARKVGYQSAGRFSELFKRYLDLTPKEYRQ 314
Cdd:pfam12833   1 LAAALGMSPRTLSRLFKRELGLSPKEYLRRLRLERARRLLLEdTGLSVAEIALALGFSDASHFSRAFRRLFGLTPSEYRR 80


                  .
gi 970962700  315 Q 315
Cdd:pfam12833  81 R 81
GlxA COG4977
Transcriptional regulator GlxA, contains an amidase domain and an AraC-type DNA-binding HTH ...
 216-315 2.83e-21

Transcriptional regulator GlxA, contains an amidase domain and an AraC-type DNA-binding HTH domain [Transcription];


Pssm-ID: 444002 [Multi-domain]  Cd Length: 318  Bit Score: 92.14  E-value: 2.83e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 970962700 216 IEHVAAHIENYYTLQLTLDHLTKISCMGATKLKKLFKEVYHCTITEYIQKQRVHQAEKLLAHTELPINEIARKVGYQSAG 295
Cdd:COG4977  212 LARAQAWMEANLEEPLSVDELARRAGMSPRTLERRFRAATGTTPARYLQRLRLERARRLLETTDLSIEEIAAACGFGSAS 291

                         90       100
                 ....*....|....*....|
gi 970962700 296 RFSELFKRYLDLTPKEYRQQ 315
Cdd:COG4977  292 HFRRAFRRRFGVSPSAYRRR 311
AdaA COG2169
Methylphosphotriester-DNA--protein-cysteine methyltransferase (N-terminal fragment of Ada), ...
 216-315 2.56e-17

Methylphosphotriester-DNA--protein-cysteine methyltransferase (N-terminal fragment of Ada), contains Zn-binding and two AraC-type DNA-binding domains [Replication, recombination and repair];


Pssm-ID: 441772 [Multi-domain]  Cd Length: 358  Bit Score: 81.25  E-value: 2.56e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 970962700 216 IEHVAAHIENYYTLQLTLDHLTKISCMGATKLKKLFKEVYHCTITEYIQKQRVHQAEKLLaHTELPINEIARKVGYQSAG 295
Cdd:COG2169   86 VARACRLIEAGAEDRPSLEDLAARLGLSPRHLRRLFKAHTGVTPKAYARARRLLRARQLL-QTGLSVTDAAYAAGFGSLS 164

                         90       100
                 ....*....|....*....|
gi 970962700 296 RFSELFKRYLDLTPKEYRQQ 315
Cdd:COG2169  165 RFYEAFKKLLGMTPSAYRRG 184
PRK10572 PRK10572
arabinose operon transcriptional regulator AraC;
150-315 1.08e-14

arabinose operon transcriptional regulator AraC;


Pssm-ID: 236717 [Multi-domain]  Cd Length: 290  Bit Score: 73.08  E-value: 1.08e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 970962700 150 TTLKATSTFSEMVILLRQIAV-YRGSDLTSalfyegkvyEALAL-IMERALsdktCHCSQISKEDIHH-----IEHVAAH 222
Cdd:PRK10572 125 LRIPDEALQPEFSDLFGQIEQaGQSEGRYS---------ELLAMnLLERLL----LRCMEAIPESLHPpmdprVREACQY 191

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 970962700 223 IENYYTLQLTLDHLTKISCMGATKLKKLFKEVYHCTITEYIQKQRVHQAEKLLAHTELPINEIARKVGYQSAGRFSELFK 302
Cdd:PRK10572 192 ISDHLASEFDIESVAQHVCLSPSRLAHLFRQQLGISVLRWREDQRISRAKLLLQTTRMPIATIGRNVGYDDQLYFSRVFK 271

                        170
                 ....*....|...
gi 970962700 303 RYLDLTPKEYRQQ 315
Cdd:PRK10572 272 KCTGASPSEFRAR 284
PRK10219 PRK10219
superoxide response transcriptional regulator SoxS;
208-316 1.87e-13

superoxide response transcriptional regulator SoxS;


Pssm-ID: 182314 [Multi-domain]  Cd Length: 107  Bit Score: 65.72  E-value: 1.87e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 970962700 208 ISKEDIhhIEHVAAHIENYYTLQLTLDHLTKISCMGATKLKKLFKEVYHCTITEYIQKQRVHQAEKLLAHTELPINEIAR 287
Cdd:PRK10219   1 MSHQKI--IQTLIAWIDEHIDQPLNIDVVAKKSGYSKWYLQRMFRTVTHQTLGDYIRQRRLLLAAVELRTTERPIFDIAM 78

                         90       100
                 ....*....|....*....|....*....
gi 970962700 288 KVGYQSAGRFSELFKRYLDLTPKEYRQQL 316
Cdd:PRK10219  79 DLGYVSQQTFSRVFRRQFDRTPSDYRHRL 107
PRK10371 PRK10371
transcriptional regulator MelR;
204-314 2.39e-10

transcriptional regulator MelR;


Pssm-ID: 182416 [Multi-domain]  Cd Length: 302  Bit Score: 60.60  E-value: 2.39e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 970962700 204 HCSQISKEDIHHIEHVAAHIENYYTLQLTLDHLTKISCMGATKLKKLFKEVYHCTITEYIQKQRVHQAEKLLAHTELPIN 283
Cdd:PRK10371 181 HKNSVSRHAQFYVSQMLGFIAENYDQALTINDVAEHVKLNANYAMGIFQRVMQLTMKQYITAMRINHVRALLSDTDKSIL 260

                         90       100       110
                 ....*....|....*....|....*....|.
gi 970962700 284 EIARKVGYQSAGRFSELFKRYLDLTPKEYRQ 314
Cdd:PRK10371 261 DIALTAGFRSSSRFYSTFGKYVGMSPQQYRK 291
PRK13501 PRK13501
HTH-type transcriptional activator RhaR;
247-316 2.06e-08

HTH-type transcriptional activator RhaR;


Pssm-ID: 184092 [Multi-domain]  Cd Length: 290  Bit Score: 54.53  E-value: 2.06e-08
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 970962700 247 LKKLFKEVYHCTITEYIQKQRVHQAEKLLAHTELPINEIARKVGYQSAGRFSELFKRYLDLTPKEYRQQL 316
Cdd:PRK13501 209 LKQLFRQQTGMSISHYLRQIRLCHAKCLLRGSEHRISDIAARCGFEDSNYFSAVFTREAGMTPRDYRQRF 278
ftrA PRK09393
transcriptional activator FtrA; Provisional
 216-315 4.40e-08

transcriptional activator FtrA; Provisional


Pssm-ID: 181818 [Multi-domain]  Cd Length: 322  Bit Score: 53.81  E-value: 4.40e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 970962700 216 IEHVAAHIenyyTLQLTLDHLTKISCMGATKLKKLFKEVYHCTITEYIQKQRVHQAEKLLAHTELPINEIARKVGYQSAG 295
Cdd:PRK09393 224 IDWMRAHL----AEPHTVASLAARAAMSPRTFLRRFEAATGMTPAEWLLRERLARARDLLESSALSIDQIAERAGFGSEE 299

                         90       100
                 ....*....|....*....|
gi 970962700 296 RFSELFKRYLDLTPKEYRQQ 315
Cdd:PRK09393 300 SLRHHFRRRAATSPAAYRKR 319
PRK13502 PRK13502
HTH-type transcriptional activator RhaR;
247-314 2.73e-07

HTH-type transcriptional activator RhaR;


Pssm-ID: 184093 [Multi-domain]  Cd Length: 282  Bit Score: 51.21  E-value: 2.73e-07
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 970962700 247 LKKLFKEVYHCTITEYIQKQRVHQAEKLLAHTELPINEIARKVGYQSAGRFSELFKRYLDLTPKEYRQ 314
Cdd:PRK13502 209 LRQQFRAQTGMTINQYLRQVRICHAQYLLQHSPLMISEISMQCGFEDSNYFSVVFTRETGMTPSQWRH 276
PRK13500 PRK13500
HTH-type transcriptional activator RhaR;
247-314 8.90e-07

HTH-type transcriptional activator RhaR;


Pssm-ID: 184091 [Multi-domain]  Cd Length: 312  Bit Score: 49.72  E-value: 8.90e-07
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 970962700 247 LKKLFKEVYHCTITEYIQKQRVHQAEKLLAHTELPINEIARKVGYQSAGRFSELFKRYLDLTPKEYRQ 314
Cdd:PRK13500 239 LRQQFRQQTGMTINQYLRQVRVCHAQYLLQHSRLLISDISTECGFEDSNYFSVVFTRETGMTPSQWRH 306
PRK15186 PRK15186
AraC family transcriptional regulator; Provisional
 186-317 2.06e-06

AraC family transcriptional regulator; Provisional


Pssm-ID: 185108 [Multi-domain]  Cd Length: 291  Bit Score: 48.52  E-value: 2.06e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 970962700 186 VYEALALIMERALSDKTChcsqisKEDIHHIehVAAHIENYYTLQLTLDHLTkiscMGATKLKKLFKEvYHCTITEYIQK 265
Cdd:PRK15186 165 IYEPEAFALFRELSQNTL------AENIYNI--IISDISRKWALKDISDSLY----MSCSTLKRKLKQ-ENTSFSEVYLN 231

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|..
gi 970962700 266 QRVHQAEKLLAHTELPINEIARKVGYQSAGRFSELFKRYLDLTPKEYRQQLS 317
Cdd:PRK15186 232 ARMNKATKLLRNSEYNITRVAYMCGYDSASYFTCVFKKHFKTTPSEFLAFLS 283
PRK13503 PRK13503
HTH-type transcriptional activator RhaS;
262-315 2.82e-06

HTH-type transcriptional activator RhaS;


Pssm-ID: 184094 [Multi-domain]  Cd Length: 278  Bit Score: 48.13  E-value: 2.82e-06
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....
gi 970962700 262 YIQKQRVHQAEKLLAHTELPINEIARKVGYQSAGRFSELFKRYLDLTPKEYRQQ 315
Cdd:PRK13503 219 YLNRLRLLKARHLLRHSDASVTDIAYRCGFGDSNHFSTLFRREFSWSPRDIRQG 272
PRK11511 PRK11511
MDR efflux pump AcrAB transcriptional activator MarA;
216-313 7.76e-06

MDR efflux pump AcrAB transcriptional activator MarA;


Pssm-ID: 236920 [Multi-domain]  Cd Length: 127  Bit Score: 44.71  E-value: 7.76e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 970962700 216 IEHVAAHIENYYTLQLTLDHLTKISCMGATKLKKLFKEVYHCTITEYIQKQRVHQAEKLLAHTELPINEIARKVGYQSAG 295
Cdd:PRK11511  11 IHSILDWIEDNLESPLSLEKVSERSGYSKWHLQRMFKKETGHSLGQYIRSRKMTEIAQKLKESNEPILYLAERYGFESQQ 90

                         90
                 ....*....|....*...
gi 970962700 296 RFSELFKRYLDLTPKEYR 313
Cdd:PRK11511  91 TLTRTFKNYFDVPPHKYR 108
HTH_AraC pfam00165
Bacterial regulatory helix-turn-helix proteins, AraC family; In the absence of arabinose, the ...
 276-314 1.16e-05

Bacterial regulatory helix-turn-helix proteins, AraC family; In the absence of arabinose, the N-terminal arm of AraC binds to the DNA binding domain (pfam00165) and helps to hold the two DNA binding domains in a relative orientation that favours DNA looping. In the presence of arabinose, the arms bind over the arabinose on the dimerization domain, thus freeing the DNA-binding domains. The freed DNA-binding domains are then able to assume a conformation suitable for binding to the adjacent DNA sites that are utilized when AraC activates transcription, and hence AraC ceases looping the DNA when arabinose is added.


Pssm-ID: 425497 [Multi-domain]  Cd Length: 42  Bit Score: 41.76  E-value: 1.16e-05
                          10        20        30
                  ....*....|....*....|....*....|....*....
gi 970962700  276 AHTELPINEIARKVGYqSAGRFSELFKRYLDLTPKEYRQ 314
Cdd:pfam00165   5 LSTNLTIADIADELGF-SRSYFSRLFKKYTGVTPSQYRH 42
PRK09685 PRK09685
DNA-binding transcriptional activator FeaR; Provisional
 218-317 9.42e-05

DNA-binding transcriptional activator FeaR; Provisional


Pssm-ID: 236612 [Multi-domain]  Cd Length: 302  Bit Score: 43.48  E-value: 9.42e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 970962700 218 HVAAHIENYYTL-QLTLDHLTKISCMGATKLKKLFKEvYHCTITEYIQKQRVHQAEKLL--AHTELPINEIARKVGYQSA 294
Cdd:PRK09685 201 KVVALIDQSIQEeILRPEWIAGELGISVRSLYRLFAE-QGLVVAQYIRNRRLDRCADDLrpAADDEKITSIAYKWGFSDS 279

                         90       100
                 ....*....|....*....|...
gi 970962700 295 GRFSELFKRYLDLTPKEYRQQLS 317
Cdd:PRK09685 280 SHFSTAFKQRFGVSPGEYRRKFR 302
PRK15185 PRK15185
transcriptional regulator HilD; Provisional
 230-312 6.34e-04

transcriptional regulator HilD; Provisional


Pssm-ID: 185107 [Multi-domain]  Cd Length: 309  Bit Score: 40.75  E-value: 6.34e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 970962700 230 QLTLDHLTKISCMGATKLK-KLFKEvyHCTITEYIQKQRVHQAEKLLAHTELPINEIARKVGYQSAGRFSELFKRYLDLT 308
Cdd:PRK15185 222 QWKLTDVADHIFMSTSTLKrKLAEE--GTSFSDIYLSARMNQAAKLLRIGNHNVNAVALKCGYDSTSYFIQCFKKYFKTT 299


                 ....
gi 970962700 309 PKEY 312
Cdd:PRK15185 300 PSTF 303
PRK10296 PRK10296
DNA-binding transcriptional regulator ChbR; Provisional
 233-317 7.96e-04

DNA-binding transcriptional regulator ChbR; Provisional


Pssm-ID: 182362 [Multi-domain]  Cd Length: 278  Bit Score: 40.51  E-value: 7.96e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 970962700 233 LDHLTKISCMGATKLKKLFKEVYHCTITEYIQKQRVHQAEKLLAHTELPINEIARKVGYQSAGRFSELFKRYLDLTPKEY 312
Cdd:PRK10296 191 LENMVRLSGKSQEYLTRATRRYYGKTPMQIINEIRINFAKKQLEMTNYSVTDIAFEAGYSSPSLFIKTFKKLTSFTPGSY 270


                 ....*
gi 970962700 313 RQQLS 317
Cdd:PRK10296 271 RKKLT 275
PRK15121 PRK15121
MDR efflux pump AcrAB transcriptional activator RobA;
247-313 1.39e-03

MDR efflux pump AcrAB transcriptional activator RobA;


Pssm-ID: 185076 [Multi-domain]  Cd Length: 289  Bit Score: 39.61  E-value: 1.39e-03
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 970962700 247 LKKLFKEVYHCTITEYIQKQRVHQAEKLLAHTELPINEIARKVGYQSAGRFSELFKRYLDLTPKEYR 313
Cdd:PRK15121  38 LQRMFKDVTGHAIGAYIRARRLSKAAVALRLTSRPILDIALQYRFDSQQTFTRAFKKQFAQTPALYR 104
PRK09978 PRK09978
DNA-binding transcriptional regulator GadX; Provisional
 222-319 2.77e-03

DNA-binding transcriptional regulator GadX; Provisional


Pssm-ID: 137624 [Multi-domain]  Cd Length: 274  Bit Score: 38.75  E-value: 2.77e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 970962700 222 HIENYYTLQLTLDHLTkiscMGATKLKKLFKEvYHCTITEYIQKQRVHQAEKLLAHTELPINEIARKVGYQSAGRFSELF 301
Cdd:PRK09978 154 NIAHEWTLARIASELL----MSPSLLKKKLRE-EETSYSQLLTECRMQRALQLIVIHGFSIKRVAVSCGYHSVSYFIYVF 228

                         90
                 ....*....|....*...
gi 970962700 302 KRYLDLTPKEYRQQLSKG 319
Cdd:PRK09978 229 RNYYGMTPTEYQERSAQG 246
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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