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Conserved domains on  [gi|9626171|ref|NP_040519|]
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encapsidation protein 52K [Human mastadenovirus C]

Protein Classification

adenoviridae leader/packaging 3 family protein( domain architecture ID 10503523)

adenoviridae leader/packaging 3 family protein similar to Human adenovirus I-leader protein and packaging protein 3 that is involved in viral genome packaging through its interaction with packaging proteins 1 and 2

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Adeno_52K pfam03052
Adenoviral protein L1 52/55-kDa; The adenoviral protein L1 52/55-kDa is expressed in both the ...
 68-269 1.02e-84

Adenoviral protein L1 52/55-kDa; The adenoviral protein L1 52/55-kDa is expressed in both the early and late stages of infection which suggests that it could play multiple roles in the viral life cycle. The L1 52/55 kDa protein interacts with the viral IVa2 protein and is required for DNA packaging. L1 53/55-kDa is required to mediate stable association between the viral DNA and empty capsid.


:

Pssm-ID: 308597  Cd Length: 198  Bit Score: 257.02  E-value: 1.02e-84
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9626171     68 LARL-GAPSPERHPRVQLKRDTREAYVPRQNLFRDREGEePEEMRDRKFHAGRELRhgLNRERLLREEDFEPDaRTGISP 146
Cdd:pfam03052   1 LAPPvGGMAPEAHPRVQLKDDVMESEVPATNLFRDRSPE-MEEERDLRYRSGRAIK--LDRDRVLEPEDFKPE-FPGLSA 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9626171    147 ARAHVAAADLVTAYEQTVNQEINFQKSFNNHVRTLVAREEVAIGLMHLWDFVSALEQNPNSKPLMAQLFLIVQHSRDNEA 226
Cdd:pfam03052  77 AKAHMVAAELHRAYEQTEVYETNFQDTFNNHIRTLLWRPEVPLGLYYLWDFLQAYLEHPNSIALTVQLLLIAQHGEDNGA 156

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|...
gi 9626171    227 FRDALLNIVEPEGRWLLDLINILQSIvVQERSLSLADKVAAIN 269
Cdd:pfam03052 157 LREALPDISEKGAEWLRDLIQMLAVI-VQERELSVREQVAAIN 198
 
Name Accession Description Interval E-value
Adeno_52K pfam03052
Adenoviral protein L1 52/55-kDa; The adenoviral protein L1 52/55-kDa is expressed in both the ...
 68-269 1.02e-84

Adenoviral protein L1 52/55-kDa; The adenoviral protein L1 52/55-kDa is expressed in both the early and late stages of infection which suggests that it could play multiple roles in the viral life cycle. The L1 52/55 kDa protein interacts with the viral IVa2 protein and is required for DNA packaging. L1 53/55-kDa is required to mediate stable association between the viral DNA and empty capsid.


Pssm-ID: 308597  Cd Length: 198  Bit Score: 257.02  E-value: 1.02e-84
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9626171     68 LARL-GAPSPERHPRVQLKRDTREAYVPRQNLFRDREGEePEEMRDRKFHAGRELRhgLNRERLLREEDFEPDaRTGISP 146
Cdd:pfam03052   1 LAPPvGGMAPEAHPRVQLKDDVMESEVPATNLFRDRSPE-MEEERDLRYRSGRAIK--LDRDRVLEPEDFKPE-FPGLSA 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9626171    147 ARAHVAAADLVTAYEQTVNQEINFQKSFNNHVRTLVAREEVAIGLMHLWDFVSALEQNPNSKPLMAQLFLIVQHSRDNEA 226
Cdd:pfam03052  77 AKAHMVAAELHRAYEQTEVYETNFQDTFNNHIRTLLWRPEVPLGLYYLWDFLQAYLEHPNSIALTVQLLLIAQHGEDNGA 156

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|...
gi 9626171    227 FRDALLNIVEPEGRWLLDLINILQSIvVQERSLSLADKVAAIN 269
Cdd:pfam03052 157 LREALPDISEKGAEWLRDLIQMLAVI-VQERELSVREQVAAIN 198
 
Name Accession Description Interval E-value
Adeno_52K pfam03052
Adenoviral protein L1 52/55-kDa; The adenoviral protein L1 52/55-kDa is expressed in both the ...
 68-269 1.02e-84

Adenoviral protein L1 52/55-kDa; The adenoviral protein L1 52/55-kDa is expressed in both the early and late stages of infection which suggests that it could play multiple roles in the viral life cycle. The L1 52/55 kDa protein interacts with the viral IVa2 protein and is required for DNA packaging. L1 53/55-kDa is required to mediate stable association between the viral DNA and empty capsid.


Pssm-ID: 308597  Cd Length: 198  Bit Score: 257.02  E-value: 1.02e-84
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9626171     68 LARL-GAPSPERHPRVQLKRDTREAYVPRQNLFRDREGEePEEMRDRKFHAGRELRhgLNRERLLREEDFEPDaRTGISP 146
Cdd:pfam03052   1 LAPPvGGMAPEAHPRVQLKDDVMESEVPATNLFRDRSPE-MEEERDLRYRSGRAIK--LDRDRVLEPEDFKPE-FPGLSA 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9626171    147 ARAHVAAADLVTAYEQTVNQEINFQKSFNNHVRTLVAREEVAIGLMHLWDFVSALEQNPNSKPLMAQLFLIVQHSRDNEA 226
Cdd:pfam03052  77 AKAHMVAAELHRAYEQTEVYETNFQDTFNNHIRTLLWRPEVPLGLYYLWDFLQAYLEHPNSIALTVQLLLIAQHGEDNGA 156

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|...
gi 9626171    227 FRDALLNIVEPEGRWLLDLINILQSIvVQERSLSLADKVAAIN 269
Cdd:pfam03052 157 LREALPDISEKGAEWLRDLIQMLAVI-VQERELSVREQVAAIN 198
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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