NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|961955812|ref|XP_014916206|]
View 

PREDICTED: host cell factor 1 [Poecilia latipinna]

Protein Classification

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
NanM COG3055
N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];
26-345 7.42e-21

N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];


:

Pssm-ID: 442289 [Multi-domain]  Cd Length: 277  Bit Score: 94.45  E-value: 7.42e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 961955812   26 WS--GPVPRPRHGHRAVAIKELMVVFGGGNEG-IVDELHVYNTATNQWfipaVRGDIPPGCAAYGFVC--DGTRLLVFGG 100
Cdd:COG3055     3 WSslPDLPTPRSEAAAALLDGKVYVAGGLSGGsASNSFEVYDPATNTW----SELAPLPGPPRHHAAAvaQDGKLYVFGG 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 961955812  101 MVEY---GKYSNDLYELQASRWEWKKLkaknpknGPPPCPRLGHSFSLVGNKCYLFGGlaNDSEDPKNNIPRYlnDLYTL 177
Cdd:COG3055    79 FTGAnpsSTPLNDVYVYDPATNTWTKL-------APMPTPRGGATALLLDGKIYVVGG--WDDGGNVAWVEVY--DPATG 147

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 961955812  178 ELRPGSSvvgwdipitygvLPPPRESHTAVVYTEkttrkSRLIIYGGMSGcrlgdlwtldidTLTWNKPSVGGTAPLPRS 257
Cdd:COG3055   148 TWTQLAP------------LPTPRDHLAAAVLPD-----GKILVIGGRNG------------SGFSNTWTTLAPLPTARA 198

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 961955812  258 LHSATTITNKMYVFGGwvplvmddvkvathekEWKCTNTLACLNLDSMCWETVlmdtleDNIPRARAGHCAVAINSRLYV 337
Cdd:COG3055   199 GHAAAVLGGKILVFGG----------------ESGFSDEVEAYDPATNTWTAL------GELPTPRHGHAAVLTDGKVYV 256

                         330
                  ....*....|
gi 961955812  338 WSG--RDGYR 345
Cdd:COG3055   257 IGGetKPGVR 266
FN3 super family cl21522
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...
 1540-1642 5.23e-03

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.


The actual alignment was detected with superfamily member pfam00041:

Pssm-ID: 473895 [Multi-domain]  Cd Length: 85  Bit Score: 37.78  E-value: 5.23e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 961955812  1540 GAPCAIKIS-KSPDGAHLTWEPPSVTSGKIIEYSVYLAIQSSQTAEAKASTPAQLAFMRVycgpnpsclvqsSSLsNAHI 1618
Cdd:pfam00041    1 SAPSNLTVTdVTSTSLTVSWTPPPDGNGPITGYEVEYRPKNSGEPWNEITVPGTTTSVTL------------TGL-KPGT 67

                           90       100
                   ....*....|....*....|....
gi 961955812  1619 DYTtkpaiiFRIAARNEKGYGPAT 1642
Cdd:pfam00041   68 EYE------VRVQAVNGGGEGPPS 85
FN3 cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...
 1504-1533 8.08e-03

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.


:

Pssm-ID: 238020 [Multi-domain]  Cd Length: 93  Bit Score: 37.48  E-value: 8.08e-03
                          10        20        30
                  ....*....|....*....|....*....|
gi 961955812 1504 LQPGTAYKFRVAGINACGRGTFSEISAFKT 1533
Cdd:cd00063    64 LKPGTEYEFRVRAVNGGGESPPSESVTVTT 93
 
Name Accession Description Interval E-value
NanM COG3055
N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];
26-345 7.42e-21

N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442289 [Multi-domain]  Cd Length: 277  Bit Score: 94.45  E-value: 7.42e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 961955812   26 WS--GPVPRPRHGHRAVAIKELMVVFGGGNEG-IVDELHVYNTATNQWfipaVRGDIPPGCAAYGFVC--DGTRLLVFGG 100
Cdd:COG3055     3 WSslPDLPTPRSEAAAALLDGKVYVAGGLSGGsASNSFEVYDPATNTW----SELAPLPGPPRHHAAAvaQDGKLYVFGG 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 961955812  101 MVEY---GKYSNDLYELQASRWEWKKLkaknpknGPPPCPRLGHSFSLVGNKCYLFGGlaNDSEDPKNNIPRYlnDLYTL 177
Cdd:COG3055    79 FTGAnpsSTPLNDVYVYDPATNTWTKL-------APMPTPRGGATALLLDGKIYVVGG--WDDGGNVAWVEVY--DPATG 147

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 961955812  178 ELRPGSSvvgwdipitygvLPPPRESHTAVVYTEkttrkSRLIIYGGMSGcrlgdlwtldidTLTWNKPSVGGTAPLPRS 257
Cdd:COG3055   148 TWTQLAP------------LPTPRDHLAAAVLPD-----GKILVIGGRNG------------SGFSNTWTTLAPLPTARA 198

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 961955812  258 LHSATTITNKMYVFGGwvplvmddvkvathekEWKCTNTLACLNLDSMCWETVlmdtleDNIPRARAGHCAVAINSRLYV 337
Cdd:COG3055   199 GHAAAVLGGKILVFGG----------------ESGFSDEVEAYDPATNTWTAL------GELPTPRHGHAAVLTDGKVYV 256

                         330
                  ....*....|
gi 961955812  338 WSG--RDGYR 345
Cdd:COG3055   257 IGGetKPGVR 266
PLN02153 PLN02153
epithiospecifier protein
 16-334 1.04e-13

epithiospecifier protein


Pssm-ID: 177814 [Multi-domain]  Cd Length: 341  Bit Score: 74.64  E-value: 1.04e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 961955812   16 LQPRWKRVLGWSGPVPRPRHGHRAVAIKELMVVFGGG---NEGIVDELHVYNTATNQWFIPAVRGDIPP-GCAAYGFVCD 91
Cdd:PLN02153    5 LQGGWIKVEQKGGKGPGPRCSHGIAVVGDKLYSFGGElkpNEHIDKDLYVFDFNTHTWSIAPANGDVPRiSCLGVRMVAV 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 961955812   92 GTRLLVFGGMVEYGKYsNDLYELQASRWEWKKLKAKNPKNGPPpcPRLGHSFSLVGNKCYLFGGLandSEDPKNNIPRYL 171
Cdd:PLN02153   85 GTKLYIFGGRDEKREF-SDFYSYDTVKNEWTFLTKLDEEGGPE--ARTFHSMASDENHVYVFGGV---SKGGLMKTPERF 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 961955812  172 NDLYTLELRPGssvvGWdipityGVLPPPRESHTA--------------VVYTEKTTrksrlIIYGGMSGCRLGDLWTLD 237
Cdd:PLN02153  159 RTIEAYNIADG----KW------VQLPDPGENFEKrggagfavvqgkiwVVYGFATS-----ILPGGKSDYESNAVQFFD 223

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 961955812  238 IDTLTWNKPSVGGTAPLPRSLHSATTITNKMYVFGGwvpLVMDDVKvaTHEKEWKCTNTLACLNLDSMCWETvLMDTLED 317
Cdd:PLN02153  224 PASGKWTEVETTGAKPSARSVFAHAVVGKYIIIFGG---EVWPDLK--GHLGPGTLSNEGYALDTETLVWEK-LGECGEP 297

                         330
                  ....*....|....*..
gi 961955812  318 NIPRARAGHCAVAINSR 334
Cdd:PLN02153  298 AMPRGWTAYTTATVYGK 314
Kelch_3 pfam13415
Galactose oxidase, central domain;
216-264 2.25e-04

Galactose oxidase, central domain;


Pssm-ID: 433188 [Multi-domain]  Cd Length: 49  Bit Score: 40.35  E-value: 2.25e-04
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|..
gi 961955812   216 KSRLIIYGG---MSGCRLGDLWTLDIDTLTWNKPsvgGTAPLPRSLHSATTI 264
Cdd:pfam13415    1 GDKLYIFGGlgfDGQTRLNDLYVYDLDTNTWTQI---GDLPPPRSGHSATYI 49
fn3 pfam00041
Fibronectin type III domain;
1540-1642 5.23e-03

Fibronectin type III domain;


Pssm-ID: 394996 [Multi-domain]  Cd Length: 85  Bit Score: 37.78  E-value: 5.23e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 961955812  1540 GAPCAIKIS-KSPDGAHLTWEPPSVTSGKIIEYSVYLAIQSSQTAEAKASTPAQLAFMRVycgpnpsclvqsSSLsNAHI 1618
Cdd:pfam00041    1 SAPSNLTVTdVTSTSLTVSWTPPPDGNGPITGYEVEYRPKNSGEPWNEITVPGTTTSVTL------------TGL-KPGT 67

                           90       100
                   ....*....|....*....|....
gi 961955812  1619 DYTtkpaiiFRIAARNEKGYGPAT 1642
Cdd:pfam00041   68 EYE------VRVQAVNGGGEGPPS 85
FN3 cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...
 1504-1533 8.08e-03

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.


Pssm-ID: 238020 [Multi-domain]  Cd Length: 93  Bit Score: 37.48  E-value: 8.08e-03
                          10        20        30
                  ....*....|....*....|....*....|
gi 961955812 1504 LQPGTAYKFRVAGINACGRGTFSEISAFKT 1533
Cdd:cd00063    64 LKPGTEYEFRVRAVNGGGESPPSESVTVTT 93
 
Name Accession Description Interval E-value
NanM COG3055
N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];
26-345 7.42e-21

N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442289 [Multi-domain]  Cd Length: 277  Bit Score: 94.45  E-value: 7.42e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 961955812   26 WS--GPVPRPRHGHRAVAIKELMVVFGGGNEG-IVDELHVYNTATNQWfipaVRGDIPPGCAAYGFVC--DGTRLLVFGG 100
Cdd:COG3055     3 WSslPDLPTPRSEAAAALLDGKVYVAGGLSGGsASNSFEVYDPATNTW----SELAPLPGPPRHHAAAvaQDGKLYVFGG 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 961955812  101 MVEY---GKYSNDLYELQASRWEWKKLkaknpknGPPPCPRLGHSFSLVGNKCYLFGGlaNDSEDPKNNIPRYlnDLYTL 177
Cdd:COG3055    79 FTGAnpsSTPLNDVYVYDPATNTWTKL-------APMPTPRGGATALLLDGKIYVVGG--WDDGGNVAWVEVY--DPATG 147

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 961955812  178 ELRPGSSvvgwdipitygvLPPPRESHTAVVYTEkttrkSRLIIYGGMSGcrlgdlwtldidTLTWNKPSVGGTAPLPRS 257
Cdd:COG3055   148 TWTQLAP------------LPTPRDHLAAAVLPD-----GKILVIGGRNG------------SGFSNTWTTLAPLPTARA 198

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 961955812  258 LHSATTITNKMYVFGGwvplvmddvkvathekEWKCTNTLACLNLDSMCWETVlmdtleDNIPRARAGHCAVAINSRLYV 337
Cdd:COG3055   199 GHAAAVLGGKILVFGG----------------ESGFSDEVEAYDPATNTWTAL------GELPTPRHGHAAVLTDGKVYV 256

                         330
                  ....*....|
gi 961955812  338 WSG--RDGYR 345
Cdd:COG3055   257 IGGetKPGVR 266
NanM COG3055
N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];
77-346 9.42e-18

N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442289 [Multi-domain]  Cd Length: 277  Bit Score: 85.21  E-value: 9.42e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 961955812   77 GDIP-PGCAAYGFVCDGtRLLVFGGMvEYGKYSNDLYELQASRWEWKKLkaknpknGPPPCPRLGHSFSLV-GNKCYLFG 154
Cdd:COG3055     7 PDLPtPRSEAAAALLDG-KVYVAGGL-SGGSASNSFEVYDPATNTWSEL-------APLPGPPRHHAAAVAqDGKLYVFG 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 961955812  155 GLandseDPKNNIPRYLNDLYTLELRPGSsvvgWdipITYGVLPPPRESHTAVVYTEKTtrksrLIIYGGMSGCRLGDLW 234
Cdd:COG3055    78 GF-----TGANPSSTPLNDVYVYDPATNT----W---TKLAPMPTPRGGATALLLDGKI-----YVVGGWDDGGNVAWVE 140

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 961955812  235 TLDIDTLTWnkpSVGGTAPLPRSLHSATTITN-KMYVFGGwvplvmddVKVATHEKEWkctntlaclnldsmcwetvlmd 313
Cdd:COG3055   141 VYDPATGTW---TQLAPLPTPRDHLAAAVLPDgKILVIGG--------RNGSGFSNTW---------------------- 187

                         250       260       270
                  ....*....|....*....|....*....|...
gi 961955812  314 TLEDNIPRARAGHCAVAINSRLYVWSGRDGYRK 346
Cdd:COG3055   188 TTLAPLPTARAGHAAAVLGGKILVFGGESGFSD 220
PLN02153 PLN02153
epithiospecifier protein
 16-334 1.04e-13

epithiospecifier protein


Pssm-ID: 177814 [Multi-domain]  Cd Length: 341  Bit Score: 74.64  E-value: 1.04e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 961955812   16 LQPRWKRVLGWSGPVPRPRHGHRAVAIKELMVVFGGG---NEGIVDELHVYNTATNQWFIPAVRGDIPP-GCAAYGFVCD 91
Cdd:PLN02153    5 LQGGWIKVEQKGGKGPGPRCSHGIAVVGDKLYSFGGElkpNEHIDKDLYVFDFNTHTWSIAPANGDVPRiSCLGVRMVAV 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 961955812   92 GTRLLVFGGMVEYGKYsNDLYELQASRWEWKKLKAKNPKNGPPpcPRLGHSFSLVGNKCYLFGGLandSEDPKNNIPRYL 171
Cdd:PLN02153   85 GTKLYIFGGRDEKREF-SDFYSYDTVKNEWTFLTKLDEEGGPE--ARTFHSMASDENHVYVFGGV---SKGGLMKTPERF 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 961955812  172 NDLYTLELRPGssvvGWdipityGVLPPPRESHTA--------------VVYTEKTTrksrlIIYGGMSGCRLGDLWTLD 237
Cdd:PLN02153  159 RTIEAYNIADG----KW------VQLPDPGENFEKrggagfavvqgkiwVVYGFATS-----ILPGGKSDYESNAVQFFD 223

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 961955812  238 IDTLTWNKPSVGGTAPLPRSLHSATTITNKMYVFGGwvpLVMDDVKvaTHEKEWKCTNTLACLNLDSMCWETvLMDTLED 317
Cdd:PLN02153  224 PASGKWTEVETTGAKPSARSVFAHAVVGKYIIIFGG---EVWPDLK--GHLGPGTLSNEGYALDTETLVWEK-LGECGEP 297

                         330
                  ....*....|....*..
gi 961955812  318 NIPRARAGHCAVAINSR 334
Cdd:PLN02153  298 AMPRGWTAYTTATVYGK 314
PLN02193 PLN02193
nitrile-specifier protein
 5-323 2.22e-13

nitrile-specifier protein


Pssm-ID: 177844 [Multi-domain]  Cd Length: 470  Bit Score: 74.61  E-value: 2.22e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 961955812    5 GSAVSGTTPSVLQPRWKRV-LGWSGPVPRPRHGHRAVAIKelMVVFGGG---NEGIVDELHVYNTATNQWFIPAVRGDIP 80
Cdd:PLN02193  138 GAYISLPSTPKLLGKWIKVeQKGEGPGLRCSHGIAQVGNK--IYSFGGEftpNQPIDKHLYVFDLETRTWSISPATGDVP 215

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 961955812   81 P-GCAAYGFVCDGTRLLVFGGMVEYGKYsNDLYELQASRWEWKKLKAKNPKngppPCPRLGHSFSLVGNKCYLFGGLAND 159
Cdd:PLN02193  216 HlSCLGVRMVSIGSTLYVFGGRDASRQY-NGFYSFDTTTNEWKLLTPVEEG----PTPRSFHSMAADEENVYVFGGVSAT 290

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 961955812  160 SE----DPKNNIPRYLNDLYTlelrPGSSVV---GWDIPITYGvlpppresHTAVVYtekttrksrliiygGMSGCRLGD 232
Cdd:PLN02193  291 ARlktlDSYNIVDKKWFHCST----PGDSFSirgGAGLEVVQG--------KVWVVY--------------GFNGCEVDD 344

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 961955812  233 LWTLDIDTLTWNKPSVGGTAPLPRSLHSATTITNKMYVFGGwvPLVMDDVkvaTHEKEWKCTNTLACLNLDSMCWETVLM 312
Cdd:PLN02193  345 VHYYDPVQDKWTQVETFGVRPSERSVFASAAVGKHIVIFGG--EIAMDPL---AHVGPGQLTDGTFALDTETLQWERLDK 419

                         330
                  ....*....|.
gi 961955812  313 DTLEDNIPRAR 323
Cdd:PLN02193  420 FGEEEETPSSR 430
PLN02193 PLN02193
nitrile-specifier protein
 92-273 3.49e-09

nitrile-specifier protein


Pssm-ID: 177844 [Multi-domain]  Cd Length: 470  Bit Score: 61.12  E-value: 3.49e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 961955812   92 GTRLLVFGGMVE--YGKYSNDLYELQA--SRWEWKKLKAKNPK---NGPPPCPRLGHSFSLVGNKCYLFGGlandSEDPK 164
Cdd:PLN02193  113 GVKFVLQGGKIVgfHGRSTDVLHSLGAyiSLPSTPKLLGKWIKveqKGEGPGLRCSHGIAQVGNKIYSFGG----EFTPN 188

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 961955812  165 NNIPRYLNdLYTLELRPgssvvgWDIPITYGVLPppresHTAVVYTEKTTRKSRLIIYGGMSGCR-LGDLWTLDIDTLTW 243
Cdd:PLN02193  189 QPIDKHLY-VFDLETRT------WSISPATGDVP-----HLSCLGVRMVSIGSTLYVFGGRDASRqYNGFYSFDTTTNEW 256

                         170       180       190
                  ....*....|....*....|....*....|
gi 961955812  244 NKPSVGGTAPLPRSLHSATTITNKMYVFGG 273
Cdd:PLN02193  257 KLLTPVEEGPTPRSFHSMAADEENVYVFGG 286
PRK14131 PRK14131
N-acetylneuraminate epimerase;
19-100 8.70e-05

N-acetylneuraminate epimerase;


Pssm-ID: 237617 [Multi-domain]  Cd Length: 376  Bit Score: 46.93  E-value: 8.70e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 961955812   19 RWKRVLGWSGPvprPRHGHRAVAIKELMVVFGG----GNEG---IVDELHVYNTATNQWFIPAVRGdiPPGCA-AYGFVC 90
Cdd:PRK14131   63 GWTKIAAFPGG---PREQAVAAFIDGKLYVFGGigktNSEGspqVFDDVYKYDPKTNSWQKLDTRS--PVGLAgHVAVSL 137

                          90
                  ....*....|
gi 961955812   91 DGTRLLVFGG 100
Cdd:PRK14131  138 HNGKAYITGG 147
NanM COG3055
N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];
28-115 9.08e-05

N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442289 [Multi-domain]  Cd Length: 277  Bit Score: 46.30  E-value: 9.08e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 961955812   28 GPVPRPRHGHRAVAIKELMVVFGGGNeGIVDELHVYNTATNQWFipaVRGDIPPGCAAYGFVCDGTRLLVFGGMVEYGKY 107
Cdd:COG3055   191 APLPTARAGHAAAVLGGKILVFGGES-GFSDEVEAYDPATNTWT---ALGELPTPRHGHAAVLTDGKVYVIGGETKPGVR 266


                  ....*...
gi 961955812  108 SNDLYELQ 115
Cdd:COG3055   267 TPLVTSAE 274
Kelch_3 pfam13415
Galactose oxidase, central domain;
216-264 2.25e-04

Galactose oxidase, central domain;


Pssm-ID: 433188 [Multi-domain]  Cd Length: 49  Bit Score: 40.35  E-value: 2.25e-04
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|..
gi 961955812   216 KSRLIIYGG---MSGCRLGDLWTLDIDTLTWNKPsvgGTAPLPRSLHSATTI 264
Cdd:pfam13415    1 GDKLYIFGGlgfDGQTRLNDLYVYDLDTNTWTQI---GDLPPPRSGHSATYI 49
Kelch_1 pfam01344
Kelch motif; The kelch motif was initially discovered in Kelch. In this protein there are six ...
 33-70 3.05e-04

Kelch motif; The kelch motif was initially discovered in Kelch. In this protein there are six copies of the motif. It has been shown that Swiss:Q04652 is related to Galactose Oxidase for which a structure has been solved. The kelch motif forms a beta sheet. Several of these sheets associate to form a beta propeller structure as found in pfam00064, pfam00400 and pfam00415.


Pssm-ID: 396078 [Multi-domain]  Cd Length: 46  Bit Score: 39.90  E-value: 3.05e-04
                           10        20        30
                   ....*....|....*....|....*....|....*....
gi 961955812    33 PRHGHRAVAIKELMVVFGGGNEG-IVDELHVYNTATNQW 70
Cdd:pfam01344    1 RRSGAGVVVVGGKIYVIGGFDGNqSLNSVEVYDPETNTW 39
Kelch_3 pfam13415
Galactose oxidase, central domain;
265-331 1.27e-03

Galactose oxidase, central domain;


Pssm-ID: 433188 [Multi-domain]  Cd Length: 49  Bit Score: 38.43  E-value: 1.27e-03
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 961955812   265 TNKMYVFGGWVPLVMDdvkvathekewkCTNTLACLNLDSMCWETVlmdtleDNIPRARAGHCAVAI 331
Cdd:pfam13415    1 GDKLYIFGGLGFDGQT------------RLNDLYVYDLDTNTWTQI------GDLPPPRSGHSATYI 49
Kelch_5 pfam13854
Kelch motif; The kelch motif was initially discovered in Kelch. In this protein there are six ...
 31-68 3.18e-03

Kelch motif; The kelch motif was initially discovered in Kelch. In this protein there are six copies of the motif. It has been shown that Swiss:Q04652 is related to Galactose Oxidase for which a structure has been solved. The kelch motif forms a beta sheet. Several of these sheets associate to form a beta propeller structure as found in pfam00064, pfam00400 and pfam00415.


Pssm-ID: 433528 [Multi-domain]  Cd Length: 41  Bit Score: 36.77  E-value: 3.18e-03
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|.
gi 961955812    31 PRPRHGHRAVAIKELMVVFGG---GNEGIVDELHVYNTATN 68
Cdd:pfam13854    1 PVPRYGHCAVTVGDYIYLYGGytgGEGQPSDDVYVLSLPTF 41
fn3 pfam00041
Fibronectin type III domain;
1540-1642 5.23e-03

Fibronectin type III domain;


Pssm-ID: 394996 [Multi-domain]  Cd Length: 85  Bit Score: 37.78  E-value: 5.23e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 961955812  1540 GAPCAIKIS-KSPDGAHLTWEPPSVTSGKIIEYSVYLAIQSSQTAEAKASTPAQLAFMRVycgpnpsclvqsSSLsNAHI 1618
Cdd:pfam00041    1 SAPSNLTVTdVTSTSLTVSWTPPPDGNGPITGYEVEYRPKNSGEPWNEITVPGTTTSVTL------------TGL-KPGT 67

                           90       100
                   ....*....|....*....|....
gi 961955812  1619 DYTtkpaiiFRIAARNEKGYGPAT 1642
Cdd:pfam00041   68 EYE------VRVQAVNGGGEGPPS 85
Kelch_4 pfam13418
Galactose oxidase, central domain;
33-81 6.01e-03

Galactose oxidase, central domain;


Pssm-ID: 433191 [Multi-domain]  Cd Length: 49  Bit Score: 36.44  E-value: 6.01e-03
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|..
gi 961955812    33 PRHGHRAVAIKELMV-VFGG--GNEGIVDELHVYNTATNQWfipAVRGDIPP 81
Cdd:pfam13418    1 PRAYHTSTSIPDDTIyLFGGegEDGTLLSDLWVFDLSTNEW---TRLGSLPS 49
NanM COG3055
N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];
242-349 6.34e-03

N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442289 [Multi-domain]  Cd Length: 277  Bit Score: 40.52  E-value: 6.34e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 961955812  242 TWnkpSVGGTAPLPRSLHSATTITNKMYVFGGWvplvmddvkvatheKEWKCTNTLACLNLDSMCWETVlmdtleDNIPR 321
Cdd:COG3055     2 TW---SSLPDLPTPRSEAAAALLDGKVYVAGGL--------------SGGSASNSFEVYDPATNTWSEL------APLPG 58

                          90       100
                  ....*....|....*....|....*....
gi 961955812  322 ARAGH-CAVAINSRLYVWSGRDGYRKAWN 349
Cdd:COG3055    59 PPRHHaAAVAQDGKLYVFGGFTGANPSST 87
FN3 cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...
 1504-1533 8.08e-03

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.


Pssm-ID: 238020 [Multi-domain]  Cd Length: 93  Bit Score: 37.48  E-value: 8.08e-03
                          10        20        30
                  ....*....|....*....|....*....|
gi 961955812 1504 LQPGTAYKFRVAGINACGRGTFSEISAFKT 1533
Cdd:cd00063    64 LKPGTEYEFRVRAVNGGGESPPSESVTVTT 93
Kelch_5 pfam13854
Kelch motif; The kelch motif was initially discovered in Kelch. In this protein there are six ...
 320-352 9.89e-03

Kelch motif; The kelch motif was initially discovered in Kelch. In this protein there are six copies of the motif. It has been shown that Swiss:Q04652 is related to Galactose Oxidase for which a structure has been solved. The kelch motif forms a beta sheet. Several of these sheets associate to form a beta propeller structure as found in pfam00064, pfam00400 and pfam00415.


Pssm-ID: 433528 [Multi-domain]  Cd Length: 41  Bit Score: 35.62  E-value: 9.89e-03
                           10        20        30
                   ....*....|....*....|....*....|...
gi 961955812   320 PRARAGHCAVAINSRLYVWSGRDGYRKAWNNQV 352
Cdd:pfam13854    1 PVPRYGHCAVTVGDYIYLYGGYTGGEGQPSDDV 33
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH