Transcription elongation factor SPT5 [Nakaseomyces glabratus]
List of domain hits
Name | Accession | Description | Interval | E-value | |||
CTD | smart01104 | Spt5 C-terminal nonapeptide repeat binding Spt4; The C-terminal domain of the transcription ... |
849-970 | 2.75e-37 | |||
Spt5 C-terminal nonapeptide repeat binding Spt4; The C-terminal domain of the transcription elongation factor protein Spt5 is necessary for binding to Spt4 to form the functional complex that regulates early transcription elongation by RNA polymerase II. The complex may be involved in pre-mRNA processing through its association with mRNA capping enzymes. This CTD domain carries a regular nonapeptide repeat that can be present in up to 18 copies, as in S. pombe. The repeat has a characteristic TPA motif. : Pssm-ID: 215026 [Multi-domain] Cd Length: 121 Bit Score: 136.11 E-value: 2.75e-37
|
|||||||
NGN_Euk | cd09888 | Eukaryotic N-Utilization Substance G (NusG) N-terminal (NGN) domain, including plant KTF1 (KOW ... |
235-321 | 3.93e-30 | |||
Eukaryotic N-Utilization Substance G (NusG) N-terminal (NGN) domain, including plant KTF1 (KOW domain-containing Transcription Factor 1); The N-Utilization Substance G (NusG) protein and its eukaryotic homolog, Spt5, are involved in transcription elongation and termination. NusG contains an NGN domain at its N-terminus and Kyrpides Ouzounis and Woese (KOW) repeats at its C-terminus. Spt5 forms an Spt4-Spt5 complex that is an essential RNA polymerase II elongation factor. NusG was originally discovered as an N-dependent antitermination enhancing activity in Escherichia coli, and has a variety of functions such as its involvement in RNA polymerase elongation and Rho-termination in bacteria. Orthologs of the NusG gene exist in all bacteria, but their functions and requirements are different. Spt5-like is homologous to the Spt5 proteins present in all eukaryotes, which is unique as it encodes a protein with an additional long carboxy-terminal extension that contains WG/GW motifs. Spt5-like, or KTF1 (KOW domain-containing Transcription Factor 1), is a RNA-directed DNA methylation (RdDM) pathway effector in plants. : Pssm-ID: 193577 [Multi-domain] Cd Length: 86 Bit Score: 114.16 E-value: 3.93e-30
|
|||||||
Spt5_N | pfam11942 | Spt5 transcription elongation factor, acidic N-terminal; This is the very acidic N-terminal ... |
150-228 | 4.06e-23 | |||
Spt5 transcription elongation factor, acidic N-terminal; This is the very acidic N-terminal region of the early transcription elongation factor Spt5. The Spt5-Spt4 complex regulates early transcription elongation by RNA polymerase II and has an imputed role in pre-mRNA processing via its physical association with mRNA capping enzymes. The actual function of this N-terminal domain is not known although it is dispensable for binding to Spt4. : Pssm-ID: 463406 Cd Length: 97 Bit Score: 94.64 E-value: 4.06e-23
|
|||||||
KOW_Spt5_5 | cd06085 | KOW domain of Spt5, repeat 5; Spt5, an eukaryotic ortholog of NusG, contains multiple KOW ... |
744-795 | 4.32e-18 | |||
KOW domain of Spt5, repeat 5; Spt5, an eukaryotic ortholog of NusG, contains multiple KOW motifs at its C-terminus. Spt5 is involved in transcription elongation and termination. KOW domain is known as an RNA-binding motif that is shared so far among some families of ribosomal proteins, the essential bacterial transcriptional elongation factor NusG, the eukaryotic chromatin elongation factor Spt5, the higher eukaryotic KIN17 proteins and Mtr4. KOW_Spt5 domains play critical roles in recruitment of multiple other eukaryotic transcription elongation and RNA biogenesis factors and additionally are involved in the binding of the eukaryotic Spt5 proteins to RNA polymerases. : Pssm-ID: 240509 Cd Length: 52 Bit Score: 78.68 E-value: 4.32e-18
|
|||||||
KOW_Spt5_1 | cd06081 | KOW domain of Spt5, repeat 1; Spt5, an eukaryotic ortholog of NusG, contains multiple KOW ... |
333-370 | 7.04e-16 | |||
KOW domain of Spt5, repeat 1; Spt5, an eukaryotic ortholog of NusG, contains multiple KOW motifs at its C-terminus. Spt5 is involved in transcription elongation and termination. KOW domain is known as an RNA-binding motif that is shared so far among some families of ribosomal proteins, the essential bacterial transcriptional elongation factor NusG, the eukaryotic chromatin elongation factor Spt5, the higher eukaryotic KIN17 proteins and Mtr4. KOW_Spt5 domains play critical roles in recruitment of multiple other eukaryotic transcription elongation and RNA biogenesis factors and additionally are involved in the binding of the eukaryotic Spt5 proteins to RNA polymerases. : Pssm-ID: 240505 Cd Length: 38 Bit Score: 72.12 E-value: 7.04e-16
|
|||||||
KOW_Spt5_3 | cd06083 | KOW domain of Spt5, repeat 3; Spt5, an eukaryotic ortholog of NusG, contains multiple KOW ... |
532-582 | 3.46e-15 | |||
KOW domain of Spt5, repeat 3; Spt5, an eukaryotic ortholog of NusG, contains multiple KOW motifs at its C-terminus. Spt5 is involved in transcription elongation and termination. KOW domain is known as an RNA-binding motif that is shared so far among some families of ribosomal proteins, the essential bacterial transcriptional elongation factor NusG, the eukaryotic chromatin elongation factor Spt5, the higher eukaryotic KIN17 proteins and Mtr4. KOW_Spt5 domains play critical roles in recruitment of multiple other eukaryotic transcription elongation and RNA biogenesis factors and additionally are involved in the binding of the eukaryotic Spt5 proteins to RNA polymerases. : Pssm-ID: 240507 Cd Length: 51 Bit Score: 70.25 E-value: 3.46e-15
|
|||||||
KOW_Spt5_2 | cd06082 | KOW domain of Spt5, repeat 2; Spt5, an eukaryotic ortholog of NusG, contains multiple KOW ... |
482-531 | 1.46e-12 | |||
KOW domain of Spt5, repeat 2; Spt5, an eukaryotic ortholog of NusG, contains multiple KOW motifs at its C-terminus. Spt5 is involved in transcription elongation and termination. KOW domain is known as an RNA-binding motif that is shared so far among some families of ribosomal proteins, the essential bacterial transcriptional elongation factor NusG, the eukaryotic chromatin elongation factor Spt5, the higher eukaryotic KIN17 proteins and Mtr4. KOW_Spt5 domains play critical roles in recruitment of multiple other eukaryotic transcription elongation and RNA biogenesis factors and additionally are involved in the binding of the eukaryotic Spt5 proteins to RNA polymerases. : Pssm-ID: 240506 Cd Length: 51 Bit Score: 62.90 E-value: 1.46e-12
|
|||||||
KOW_Spt5_4 | cd06084 | KOW domain of Spt5, repeat 4; Spt5, an eukaryotic ortholog of NusG, contains multiple KOW ... |
660-697 | 1.70e-06 | |||
KOW domain of Spt5, repeat 4; Spt5, an eukaryotic ortholog of NusG, contains multiple KOW motifs at its C-terminus. Spt5 is involved in transcription elongation and termination. KOW domain is known as an RNA-binding motif that is shared so far among some families of ribosomal proteins, the essential bacterial transcriptional elongation factor NusG, the eukaryotic chromatin elongation factor Spt5, the higher eukaryotic KIN17 proteins and Mtr4. KOW_Spt5 domains play critical roles in recruitment of multiple other eukaryotic transcription elongation and RNA biogenesis factors and additionally are involved in the binding of the eukaryotic Spt5 proteins to RNA polymerases. : Pssm-ID: 240508 Cd Length: 43 Bit Score: 45.59 E-value: 1.70e-06
|
|||||||
Name | Accession | Description | Interval | E-value | ||||
CTD | smart01104 | Spt5 C-terminal nonapeptide repeat binding Spt4; The C-terminal domain of the transcription ... |
849-970 | 2.75e-37 | ||||
Spt5 C-terminal nonapeptide repeat binding Spt4; The C-terminal domain of the transcription elongation factor protein Spt5 is necessary for binding to Spt4 to form the functional complex that regulates early transcription elongation by RNA polymerase II. The complex may be involved in pre-mRNA processing through its association with mRNA capping enzymes. This CTD domain carries a regular nonapeptide repeat that can be present in up to 18 copies, as in S. pombe. The repeat has a characteristic TPA motif. Pssm-ID: 215026 [Multi-domain] Cd Length: 121 Bit Score: 136.11 E-value: 2.75e-37
|
||||||||
NGN_Euk | cd09888 | Eukaryotic N-Utilization Substance G (NusG) N-terminal (NGN) domain, including plant KTF1 (KOW ... |
235-321 | 3.93e-30 | ||||
Eukaryotic N-Utilization Substance G (NusG) N-terminal (NGN) domain, including plant KTF1 (KOW domain-containing Transcription Factor 1); The N-Utilization Substance G (NusG) protein and its eukaryotic homolog, Spt5, are involved in transcription elongation and termination. NusG contains an NGN domain at its N-terminus and Kyrpides Ouzounis and Woese (KOW) repeats at its C-terminus. Spt5 forms an Spt4-Spt5 complex that is an essential RNA polymerase II elongation factor. NusG was originally discovered as an N-dependent antitermination enhancing activity in Escherichia coli, and has a variety of functions such as its involvement in RNA polymerase elongation and Rho-termination in bacteria. Orthologs of the NusG gene exist in all bacteria, but their functions and requirements are different. Spt5-like is homologous to the Spt5 proteins present in all eukaryotes, which is unique as it encodes a protein with an additional long carboxy-terminal extension that contains WG/GW motifs. Spt5-like, or KTF1 (KOW domain-containing Transcription Factor 1), is a RNA-directed DNA methylation (RdDM) pathway effector in plants. Pssm-ID: 193577 [Multi-domain] Cd Length: 86 Bit Score: 114.16 E-value: 3.93e-30
|
||||||||
Spt5_N | pfam11942 | Spt5 transcription elongation factor, acidic N-terminal; This is the very acidic N-terminal ... |
150-228 | 4.06e-23 | ||||
Spt5 transcription elongation factor, acidic N-terminal; This is the very acidic N-terminal region of the early transcription elongation factor Spt5. The Spt5-Spt4 complex regulates early transcription elongation by RNA polymerase II and has an imputed role in pre-mRNA processing via its physical association with mRNA capping enzymes. The actual function of this N-terminal domain is not known although it is dispensable for binding to Spt4. Pssm-ID: 463406 Cd Length: 97 Bit Score: 94.64 E-value: 4.06e-23
|
||||||||
Spt5-NGN | pfam03439 | Early transcription elongation factor of RNA pol II, NGN section; Spt5p and prokaryotic NusG ... |
235-320 | 8.49e-23 | ||||
Early transcription elongation factor of RNA pol II, NGN section; Spt5p and prokaryotic NusG are shown to contain a novel 'NGN' domain. The combined NGN and KOW motif regions of Spt5 form the binding domain with Spt4. Spt5 complexes with Spt4 as a 1:1 heterodimer snf this Spt5-Spt4 complex regulates early transcription elongation by RNA polymerase II and has an imputed role in pre-mRNA processing via its physical association with mRNA capping enzymes. The Schizosaccharomyces pombe core Spt5-Spt4 complex is a heterodimer bearing a trypsin-resistant Spt4-binding domain within the Spt5 subunit. Pssm-ID: 397481 Cd Length: 84 Bit Score: 93.03 E-value: 8.49e-23
|
||||||||
KOW_Spt5_5 | cd06085 | KOW domain of Spt5, repeat 5; Spt5, an eukaryotic ortholog of NusG, contains multiple KOW ... |
744-795 | 4.32e-18 | ||||
KOW domain of Spt5, repeat 5; Spt5, an eukaryotic ortholog of NusG, contains multiple KOW motifs at its C-terminus. Spt5 is involved in transcription elongation and termination. KOW domain is known as an RNA-binding motif that is shared so far among some families of ribosomal proteins, the essential bacterial transcriptional elongation factor NusG, the eukaryotic chromatin elongation factor Spt5, the higher eukaryotic KIN17 proteins and Mtr4. KOW_Spt5 domains play critical roles in recruitment of multiple other eukaryotic transcription elongation and RNA biogenesis factors and additionally are involved in the binding of the eukaryotic Spt5 proteins to RNA polymerases. Pssm-ID: 240509 Cd Length: 52 Bit Score: 78.68 E-value: 4.32e-18
|
||||||||
KOW_Spt5_1 | cd06081 | KOW domain of Spt5, repeat 1; Spt5, an eukaryotic ortholog of NusG, contains multiple KOW ... |
333-370 | 7.04e-16 | ||||
KOW domain of Spt5, repeat 1; Spt5, an eukaryotic ortholog of NusG, contains multiple KOW motifs at its C-terminus. Spt5 is involved in transcription elongation and termination. KOW domain is known as an RNA-binding motif that is shared so far among some families of ribosomal proteins, the essential bacterial transcriptional elongation factor NusG, the eukaryotic chromatin elongation factor Spt5, the higher eukaryotic KIN17 proteins and Mtr4. KOW_Spt5 domains play critical roles in recruitment of multiple other eukaryotic transcription elongation and RNA biogenesis factors and additionally are involved in the binding of the eukaryotic Spt5 proteins to RNA polymerases. Pssm-ID: 240505 Cd Length: 38 Bit Score: 72.12 E-value: 7.04e-16
|
||||||||
KOW_Spt5_3 | cd06083 | KOW domain of Spt5, repeat 3; Spt5, an eukaryotic ortholog of NusG, contains multiple KOW ... |
532-582 | 3.46e-15 | ||||
KOW domain of Spt5, repeat 3; Spt5, an eukaryotic ortholog of NusG, contains multiple KOW motifs at its C-terminus. Spt5 is involved in transcription elongation and termination. KOW domain is known as an RNA-binding motif that is shared so far among some families of ribosomal proteins, the essential bacterial transcriptional elongation factor NusG, the eukaryotic chromatin elongation factor Spt5, the higher eukaryotic KIN17 proteins and Mtr4. KOW_Spt5 domains play critical roles in recruitment of multiple other eukaryotic transcription elongation and RNA biogenesis factors and additionally are involved in the binding of the eukaryotic Spt5 proteins to RNA polymerases. Pssm-ID: 240507 Cd Length: 51 Bit Score: 70.25 E-value: 3.46e-15
|
||||||||
CTD | pfam12815 | Spt5 C-terminal nonapeptide repeat binding Spt4; The C-terminal domain of the transcription ... |
860-938 | 1.56e-13 | ||||
Spt5 C-terminal nonapeptide repeat binding Spt4; The C-terminal domain of the transcription elongation factor protein Spt5 is necessary for binding to Spt4 to form the functional complex that regulates early transcription elongation by RNA polymerase II. The complex may be involved in pre-mRNA processing through its association with mRNA capping enzymes. This CTD domain carries a regular nonapeptide repeat that can be present in up to 18 copies, as in S. pombe. The repeat has a characteriztic TPA motif. Pssm-ID: 372327 [Multi-domain] Cd Length: 71 Bit Score: 66.31 E-value: 1.56e-13
|
||||||||
KOW_Spt5_2 | cd06082 | KOW domain of Spt5, repeat 2; Spt5, an eukaryotic ortholog of NusG, contains multiple KOW ... |
482-531 | 1.46e-12 | ||||
KOW domain of Spt5, repeat 2; Spt5, an eukaryotic ortholog of NusG, contains multiple KOW motifs at its C-terminus. Spt5 is involved in transcription elongation and termination. KOW domain is known as an RNA-binding motif that is shared so far among some families of ribosomal proteins, the essential bacterial transcriptional elongation factor NusG, the eukaryotic chromatin elongation factor Spt5, the higher eukaryotic KIN17 proteins and Mtr4. KOW_Spt5 domains play critical roles in recruitment of multiple other eukaryotic transcription elongation and RNA biogenesis factors and additionally are involved in the binding of the eukaryotic Spt5 proteins to RNA polymerases. Pssm-ID: 240506 Cd Length: 51 Bit Score: 62.90 E-value: 1.46e-12
|
||||||||
Chi1 | COG3469 | Chitinase [Carbohydrate transport and metabolism]; |
822-971 | 3.07e-07 | ||||
Chitinase [Carbohydrate transport and metabolism]; Pssm-ID: 442692 [Multi-domain] Cd Length: 534 Bit Score: 54.37 E-value: 3.07e-07
|
||||||||
KOW_elon_Spt5 | TIGR00405 | transcription elongation factor Spt5; This protein contains a KOW domain, shared by bacterial ... |
236-365 | 3.10e-07 | ||||
transcription elongation factor Spt5; This protein contains a KOW domain, shared by bacterial NusG and the uL24 (previously L24p/L26e) family of ribosomal proteins. The most recent papers and crystal structures make this a transcription elongation factor rather than a ribosomal protein. Pssm-ID: 129499 [Multi-domain] Cd Length: 145 Bit Score: 50.66 E-value: 3.10e-07
|
||||||||
NGN | smart00738 | In Spt5p, this domain may confer affinity for Spt4p. It possesses a RNP-like fold; In Spt5p, ... |
235-322 | 6.03e-07 | ||||
In Spt5p, this domain may confer affinity for Spt4p. It possesses a RNP-like fold; In Spt5p, this domain may confer affinity for Spt4p.Spt4p Pssm-ID: 197850 [Multi-domain] Cd Length: 106 Bit Score: 48.91 E-value: 6.03e-07
|
||||||||
KOW_Spt5_4 | cd06084 | KOW domain of Spt5, repeat 4; Spt5, an eukaryotic ortholog of NusG, contains multiple KOW ... |
660-697 | 1.70e-06 | ||||
KOW domain of Spt5, repeat 4; Spt5, an eukaryotic ortholog of NusG, contains multiple KOW motifs at its C-terminus. Spt5 is involved in transcription elongation and termination. KOW domain is known as an RNA-binding motif that is shared so far among some families of ribosomal proteins, the essential bacterial transcriptional elongation factor NusG, the eukaryotic chromatin elongation factor Spt5, the higher eukaryotic KIN17 proteins and Mtr4. KOW_Spt5 domains play critical roles in recruitment of multiple other eukaryotic transcription elongation and RNA biogenesis factors and additionally are involved in the binding of the eukaryotic Spt5 proteins to RNA polymerases. Pssm-ID: 240508 Cd Length: 43 Bit Score: 45.59 E-value: 1.70e-06
|
||||||||
nusG | PRK08559 | transcription antitermination protein NusG; Validated |
235-365 | 3.56e-06 | ||||
transcription antitermination protein NusG; Validated Pssm-ID: 181467 [Multi-domain] Cd Length: 153 Bit Score: 47.94 E-value: 3.56e-06
|
||||||||
dermokine | cd21118 | dermokine; Dermokine, also known as epidermis-specific secreted protein SK30/SK89, is a ... |
800-1006 | 5.66e-05 | ||||
dermokine; Dermokine, also known as epidermis-specific secreted protein SK30/SK89, is a skin-specific glycoprotein that may play a regulatory role in the crosstalk between barrier dysfunction and inflammation, and therefore play a role in inflammatory diseases such as psoriasis. Dermokine is one of the most highly expressed proteins in differentiating keratinocytes, found mainly in the spinous and granular layers of the epidermis, but also in the epithelia of the small intestine, macrophages of the lung, and endothelial cells of the lung. Mouse dermokine has been reported to be encoded by 22 exons, and its expression leads to alpha, beta, and gamma transcripts. Pssm-ID: 411053 [Multi-domain] Cd Length: 495 Bit Score: 46.92 E-value: 5.66e-05
|
||||||||
PRK13875 | PRK13875 | conjugal transfer protein TrbL; Provisional |
833-960 | 2.43e-04 | ||||
conjugal transfer protein TrbL; Provisional Pssm-ID: 237537 Cd Length: 440 Bit Score: 44.90 E-value: 2.43e-04
|
||||||||
KOW | pfam00467 | KOW motif; This family has been extended to coincide with ref. The KOW (Kyprides, Ouzounis, ... |
750-780 | 5.37e-04 | ||||
KOW motif; This family has been extended to coincide with ref. The KOW (Kyprides, Ouzounis, Woese) motif is found in a variety of ribosomal proteins and NusG. Pssm-ID: 425698 [Multi-domain] Cd Length: 32 Bit Score: 38.14 E-value: 5.37e-04
|
||||||||
ser_rich_anae_1 | NF033849 | serine-rich protein; This serine-rich protein belongs to a family with large size (over 1000 ... |
822-971 | 2.31e-03 | ||||
serine-rich protein; This serine-rich protein belongs to a family with large size (over 1000 amino acids), which a highly serine-rich central region that averages over 300 aa in length. Species encoding members of this family of proteins tend to be anaerobic bacteria, including Gram-positive bacteria of the human gut microbiome and Chloroflexi from marine sediments. Pssm-ID: 468206 [Multi-domain] Cd Length: 1122 Bit Score: 41.91 E-value: 2.31e-03
|
||||||||
Name | Accession | Description | Interval | E-value | ||||
CTD | smart01104 | Spt5 C-terminal nonapeptide repeat binding Spt4; The C-terminal domain of the transcription ... |
849-970 | 2.75e-37 | ||||
Spt5 C-terminal nonapeptide repeat binding Spt4; The C-terminal domain of the transcription elongation factor protein Spt5 is necessary for binding to Spt4 to form the functional complex that regulates early transcription elongation by RNA polymerase II. The complex may be involved in pre-mRNA processing through its association with mRNA capping enzymes. This CTD domain carries a regular nonapeptide repeat that can be present in up to 18 copies, as in S. pombe. The repeat has a characteristic TPA motif. Pssm-ID: 215026 [Multi-domain] Cd Length: 121 Bit Score: 136.11 E-value: 2.75e-37
|
||||||||
NGN_Euk | cd09888 | Eukaryotic N-Utilization Substance G (NusG) N-terminal (NGN) domain, including plant KTF1 (KOW ... |
235-321 | 3.93e-30 | ||||
Eukaryotic N-Utilization Substance G (NusG) N-terminal (NGN) domain, including plant KTF1 (KOW domain-containing Transcription Factor 1); The N-Utilization Substance G (NusG) protein and its eukaryotic homolog, Spt5, are involved in transcription elongation and termination. NusG contains an NGN domain at its N-terminus and Kyrpides Ouzounis and Woese (KOW) repeats at its C-terminus. Spt5 forms an Spt4-Spt5 complex that is an essential RNA polymerase II elongation factor. NusG was originally discovered as an N-dependent antitermination enhancing activity in Escherichia coli, and has a variety of functions such as its involvement in RNA polymerase elongation and Rho-termination in bacteria. Orthologs of the NusG gene exist in all bacteria, but their functions and requirements are different. Spt5-like is homologous to the Spt5 proteins present in all eukaryotes, which is unique as it encodes a protein with an additional long carboxy-terminal extension that contains WG/GW motifs. Spt5-like, or KTF1 (KOW domain-containing Transcription Factor 1), is a RNA-directed DNA methylation (RdDM) pathway effector in plants. Pssm-ID: 193577 [Multi-domain] Cd Length: 86 Bit Score: 114.16 E-value: 3.93e-30
|
||||||||
Spt5_N | pfam11942 | Spt5 transcription elongation factor, acidic N-terminal; This is the very acidic N-terminal ... |
150-228 | 4.06e-23 | ||||
Spt5 transcription elongation factor, acidic N-terminal; This is the very acidic N-terminal region of the early transcription elongation factor Spt5. The Spt5-Spt4 complex regulates early transcription elongation by RNA polymerase II and has an imputed role in pre-mRNA processing via its physical association with mRNA capping enzymes. The actual function of this N-terminal domain is not known although it is dispensable for binding to Spt4. Pssm-ID: 463406 Cd Length: 97 Bit Score: 94.64 E-value: 4.06e-23
|
||||||||
Spt5-NGN | pfam03439 | Early transcription elongation factor of RNA pol II, NGN section; Spt5p and prokaryotic NusG ... |
235-320 | 8.49e-23 | ||||
Early transcription elongation factor of RNA pol II, NGN section; Spt5p and prokaryotic NusG are shown to contain a novel 'NGN' domain. The combined NGN and KOW motif regions of Spt5 form the binding domain with Spt4. Spt5 complexes with Spt4 as a 1:1 heterodimer snf this Spt5-Spt4 complex regulates early transcription elongation by RNA polymerase II and has an imputed role in pre-mRNA processing via its physical association with mRNA capping enzymes. The Schizosaccharomyces pombe core Spt5-Spt4 complex is a heterodimer bearing a trypsin-resistant Spt4-binding domain within the Spt5 subunit. Pssm-ID: 397481 Cd Length: 84 Bit Score: 93.03 E-value: 8.49e-23
|
||||||||
KOW_Spt5_5 | cd06085 | KOW domain of Spt5, repeat 5; Spt5, an eukaryotic ortholog of NusG, contains multiple KOW ... |
744-795 | 4.32e-18 | ||||
KOW domain of Spt5, repeat 5; Spt5, an eukaryotic ortholog of NusG, contains multiple KOW motifs at its C-terminus. Spt5 is involved in transcription elongation and termination. KOW domain is known as an RNA-binding motif that is shared so far among some families of ribosomal proteins, the essential bacterial transcriptional elongation factor NusG, the eukaryotic chromatin elongation factor Spt5, the higher eukaryotic KIN17 proteins and Mtr4. KOW_Spt5 domains play critical roles in recruitment of multiple other eukaryotic transcription elongation and RNA biogenesis factors and additionally are involved in the binding of the eukaryotic Spt5 proteins to RNA polymerases. Pssm-ID: 240509 Cd Length: 52 Bit Score: 78.68 E-value: 4.32e-18
|
||||||||
KOW_Spt5_1 | cd06081 | KOW domain of Spt5, repeat 1; Spt5, an eukaryotic ortholog of NusG, contains multiple KOW ... |
333-370 | 7.04e-16 | ||||
KOW domain of Spt5, repeat 1; Spt5, an eukaryotic ortholog of NusG, contains multiple KOW motifs at its C-terminus. Spt5 is involved in transcription elongation and termination. KOW domain is known as an RNA-binding motif that is shared so far among some families of ribosomal proteins, the essential bacterial transcriptional elongation factor NusG, the eukaryotic chromatin elongation factor Spt5, the higher eukaryotic KIN17 proteins and Mtr4. KOW_Spt5 domains play critical roles in recruitment of multiple other eukaryotic transcription elongation and RNA biogenesis factors and additionally are involved in the binding of the eukaryotic Spt5 proteins to RNA polymerases. Pssm-ID: 240505 Cd Length: 38 Bit Score: 72.12 E-value: 7.04e-16
|
||||||||
KOW_Spt5_3 | cd06083 | KOW domain of Spt5, repeat 3; Spt5, an eukaryotic ortholog of NusG, contains multiple KOW ... |
532-582 | 3.46e-15 | ||||
KOW domain of Spt5, repeat 3; Spt5, an eukaryotic ortholog of NusG, contains multiple KOW motifs at its C-terminus. Spt5 is involved in transcription elongation and termination. KOW domain is known as an RNA-binding motif that is shared so far among some families of ribosomal proteins, the essential bacterial transcriptional elongation factor NusG, the eukaryotic chromatin elongation factor Spt5, the higher eukaryotic KIN17 proteins and Mtr4. KOW_Spt5 domains play critical roles in recruitment of multiple other eukaryotic transcription elongation and RNA biogenesis factors and additionally are involved in the binding of the eukaryotic Spt5 proteins to RNA polymerases. Pssm-ID: 240507 Cd Length: 51 Bit Score: 70.25 E-value: 3.46e-15
|
||||||||
CTD | pfam12815 | Spt5 C-terminal nonapeptide repeat binding Spt4; The C-terminal domain of the transcription ... |
860-938 | 1.56e-13 | ||||
Spt5 C-terminal nonapeptide repeat binding Spt4; The C-terminal domain of the transcription elongation factor protein Spt5 is necessary for binding to Spt4 to form the functional complex that regulates early transcription elongation by RNA polymerase II. The complex may be involved in pre-mRNA processing through its association with mRNA capping enzymes. This CTD domain carries a regular nonapeptide repeat that can be present in up to 18 copies, as in S. pombe. The repeat has a characteriztic TPA motif. Pssm-ID: 372327 [Multi-domain] Cd Length: 71 Bit Score: 66.31 E-value: 1.56e-13
|
||||||||
KOW_Spt5_2 | cd06082 | KOW domain of Spt5, repeat 2; Spt5, an eukaryotic ortholog of NusG, contains multiple KOW ... |
482-531 | 1.46e-12 | ||||
KOW domain of Spt5, repeat 2; Spt5, an eukaryotic ortholog of NusG, contains multiple KOW motifs at its C-terminus. Spt5 is involved in transcription elongation and termination. KOW domain is known as an RNA-binding motif that is shared so far among some families of ribosomal proteins, the essential bacterial transcriptional elongation factor NusG, the eukaryotic chromatin elongation factor Spt5, the higher eukaryotic KIN17 proteins and Mtr4. KOW_Spt5 domains play critical roles in recruitment of multiple other eukaryotic transcription elongation and RNA biogenesis factors and additionally are involved in the binding of the eukaryotic Spt5 proteins to RNA polymerases. Pssm-ID: 240506 Cd Length: 51 Bit Score: 62.90 E-value: 1.46e-12
|
||||||||
Chi1 | COG3469 | Chitinase [Carbohydrate transport and metabolism]; |
822-971 | 3.07e-07 | ||||
Chitinase [Carbohydrate transport and metabolism]; Pssm-ID: 442692 [Multi-domain] Cd Length: 534 Bit Score: 54.37 E-value: 3.07e-07
|
||||||||
KOW_elon_Spt5 | TIGR00405 | transcription elongation factor Spt5; This protein contains a KOW domain, shared by bacterial ... |
236-365 | 3.10e-07 | ||||
transcription elongation factor Spt5; This protein contains a KOW domain, shared by bacterial NusG and the uL24 (previously L24p/L26e) family of ribosomal proteins. The most recent papers and crystal structures make this a transcription elongation factor rather than a ribosomal protein. Pssm-ID: 129499 [Multi-domain] Cd Length: 145 Bit Score: 50.66 E-value: 3.10e-07
|
||||||||
NGN | smart00738 | In Spt5p, this domain may confer affinity for Spt4p. It possesses a RNP-like fold; In Spt5p, ... |
235-322 | 6.03e-07 | ||||
In Spt5p, this domain may confer affinity for Spt4p. It possesses a RNP-like fold; In Spt5p, this domain may confer affinity for Spt4p.Spt4p Pssm-ID: 197850 [Multi-domain] Cd Length: 106 Bit Score: 48.91 E-value: 6.03e-07
|
||||||||
KOW_Spt5_4 | cd06084 | KOW domain of Spt5, repeat 4; Spt5, an eukaryotic ortholog of NusG, contains multiple KOW ... |
660-697 | 1.70e-06 | ||||
KOW domain of Spt5, repeat 4; Spt5, an eukaryotic ortholog of NusG, contains multiple KOW motifs at its C-terminus. Spt5 is involved in transcription elongation and termination. KOW domain is known as an RNA-binding motif that is shared so far among some families of ribosomal proteins, the essential bacterial transcriptional elongation factor NusG, the eukaryotic chromatin elongation factor Spt5, the higher eukaryotic KIN17 proteins and Mtr4. KOW_Spt5 domains play critical roles in recruitment of multiple other eukaryotic transcription elongation and RNA biogenesis factors and additionally are involved in the binding of the eukaryotic Spt5 proteins to RNA polymerases. Pssm-ID: 240508 Cd Length: 43 Bit Score: 45.59 E-value: 1.70e-06
|
||||||||
nusG | PRK08559 | transcription antitermination protein NusG; Validated |
235-365 | 3.56e-06 | ||||
transcription antitermination protein NusG; Validated Pssm-ID: 181467 [Multi-domain] Cd Length: 153 Bit Score: 47.94 E-value: 3.56e-06
|
||||||||
dermokine | cd21118 | dermokine; Dermokine, also known as epidermis-specific secreted protein SK30/SK89, is a ... |
800-1006 | 5.66e-05 | ||||
dermokine; Dermokine, also known as epidermis-specific secreted protein SK30/SK89, is a skin-specific glycoprotein that may play a regulatory role in the crosstalk between barrier dysfunction and inflammation, and therefore play a role in inflammatory diseases such as psoriasis. Dermokine is one of the most highly expressed proteins in differentiating keratinocytes, found mainly in the spinous and granular layers of the epidermis, but also in the epithelia of the small intestine, macrophages of the lung, and endothelial cells of the lung. Mouse dermokine has been reported to be encoded by 22 exons, and its expression leads to alpha, beta, and gamma transcripts. Pssm-ID: 411053 [Multi-domain] Cd Length: 495 Bit Score: 46.92 E-value: 5.66e-05
|
||||||||
TrbL | COG3846 | Type IV secretory pathway, TrbL components [Intracellular trafficking, secretion, and ... |
826-961 | 5.75e-05 | ||||
Type IV secretory pathway, TrbL components [Intracellular trafficking, secretion, and vesicular transport]; Pssm-ID: 443056 [Multi-domain] Cd Length: 443 Bit Score: 46.86 E-value: 5.75e-05
|
||||||||
TrbL | COG3846 | Type IV secretory pathway, TrbL components [Intracellular trafficking, secretion, and ... |
844-971 | 8.33e-05 | ||||
Type IV secretory pathway, TrbL components [Intracellular trafficking, secretion, and vesicular transport]; Pssm-ID: 443056 [Multi-domain] Cd Length: 443 Bit Score: 46.08 E-value: 8.33e-05
|
||||||||
dermokine | cd21118 | dermokine; Dermokine, also known as epidermis-specific secreted protein SK30/SK89, is a ... |
834-946 | 1.09e-04 | ||||
dermokine; Dermokine, also known as epidermis-specific secreted protein SK30/SK89, is a skin-specific glycoprotein that may play a regulatory role in the crosstalk between barrier dysfunction and inflammation, and therefore play a role in inflammatory diseases such as psoriasis. Dermokine is one of the most highly expressed proteins in differentiating keratinocytes, found mainly in the spinous and granular layers of the epidermis, but also in the epithelia of the small intestine, macrophages of the lung, and endothelial cells of the lung. Mouse dermokine has been reported to be encoded by 22 exons, and its expression leads to alpha, beta, and gamma transcripts. Pssm-ID: 411053 [Multi-domain] Cd Length: 495 Bit Score: 46.15 E-value: 1.09e-04
|
||||||||
PRK13875 | PRK13875 | conjugal transfer protein TrbL; Provisional |
833-960 | 2.43e-04 | ||||
conjugal transfer protein TrbL; Provisional Pssm-ID: 237537 Cd Length: 440 Bit Score: 44.90 E-value: 2.43e-04
|
||||||||
dermokine | cd21118 | dermokine; Dermokine, also known as epidermis-specific secreted protein SK30/SK89, is a ... |
834-968 | 2.48e-04 | ||||
dermokine; Dermokine, also known as epidermis-specific secreted protein SK30/SK89, is a skin-specific glycoprotein that may play a regulatory role in the crosstalk between barrier dysfunction and inflammation, and therefore play a role in inflammatory diseases such as psoriasis. Dermokine is one of the most highly expressed proteins in differentiating keratinocytes, found mainly in the spinous and granular layers of the epidermis, but also in the epithelia of the small intestine, macrophages of the lung, and endothelial cells of the lung. Mouse dermokine has been reported to be encoded by 22 exons, and its expression leads to alpha, beta, and gamma transcripts. Pssm-ID: 411053 [Multi-domain] Cd Length: 495 Bit Score: 44.99 E-value: 2.48e-04
|
||||||||
AidA | COG3468 | Autotransporter adhesin AidA [Cell wall/membrane/envelope biogenesis, Intracellular ... |
834-971 | 5.08e-04 | ||||
Autotransporter adhesin AidA [Cell wall/membrane/envelope biogenesis, Intracellular trafficking, secretion, and vesicular transport]; Pssm-ID: 442691 [Multi-domain] Cd Length: 846 Bit Score: 44.17 E-value: 5.08e-04
|
||||||||
KOW | pfam00467 | KOW motif; This family has been extended to coincide with ref. The KOW (Kyprides, Ouzounis, ... |
750-780 | 5.37e-04 | ||||
KOW motif; This family has been extended to coincide with ref. The KOW (Kyprides, Ouzounis, Woese) motif is found in a variety of ribosomal proteins and NusG. Pssm-ID: 425698 [Multi-domain] Cd Length: 32 Bit Score: 38.14 E-value: 5.37e-04
|
||||||||
PTZ00473 | PTZ00473 | Plasmodium Vir superfamily; Provisional |
850-964 | 1.03e-03 | ||||
Plasmodium Vir superfamily; Provisional Pssm-ID: 240430 [Multi-domain] Cd Length: 420 Bit Score: 42.53 E-value: 1.03e-03
|
||||||||
dermokine | cd21118 | dermokine; Dermokine, also known as epidermis-specific secreted protein SK30/SK89, is a ... |
833-1005 | 1.59e-03 | ||||
dermokine; Dermokine, also known as epidermis-specific secreted protein SK30/SK89, is a skin-specific glycoprotein that may play a regulatory role in the crosstalk between barrier dysfunction and inflammation, and therefore play a role in inflammatory diseases such as psoriasis. Dermokine is one of the most highly expressed proteins in differentiating keratinocytes, found mainly in the spinous and granular layers of the epidermis, but also in the epithelia of the small intestine, macrophages of the lung, and endothelial cells of the lung. Mouse dermokine has been reported to be encoded by 22 exons, and its expression leads to alpha, beta, and gamma transcripts. Pssm-ID: 411053 [Multi-domain] Cd Length: 495 Bit Score: 42.29 E-value: 1.59e-03
|
||||||||
ser_rich_anae_1 | NF033849 | serine-rich protein; This serine-rich protein belongs to a family with large size (over 1000 ... |
822-971 | 2.31e-03 | ||||
serine-rich protein; This serine-rich protein belongs to a family with large size (over 1000 amino acids), which a highly serine-rich central region that averages over 300 aa in length. Species encoding members of this family of proteins tend to be anaerobic bacteria, including Gram-positive bacteria of the human gut microbiome and Chloroflexi from marine sediments. Pssm-ID: 468206 [Multi-domain] Cd Length: 1122 Bit Score: 41.91 E-value: 2.31e-03
|
||||||||
PTZ00473 | PTZ00473 | Plasmodium Vir superfamily; Provisional |
845-948 | 2.69e-03 | ||||
Plasmodium Vir superfamily; Provisional Pssm-ID: 240430 [Multi-domain] Cd Length: 420 Bit Score: 41.37 E-value: 2.69e-03
|
||||||||
PRK13875 | PRK13875 | conjugal transfer protein TrbL; Provisional |
870-972 | 2.74e-03 | ||||
conjugal transfer protein TrbL; Provisional Pssm-ID: 237537 Cd Length: 440 Bit Score: 41.43 E-value: 2.74e-03
|
||||||||
Gly_rich | pfam12810 | Glycine rich protein; This family of proteins is greatly expanded in Trichomonas vaginalis. ... |
852-1003 | 4.28e-03 | ||||
Glycine rich protein; This family of proteins is greatly expanded in Trichomonas vaginalis. The proteins are composed of several glycine rich motifs interspersed through the sequence. Although many proteins have been annotated by similarity in the family these annotations given the biased composition of the sequences these are unlikely to be functionally relevant. Pssm-ID: 403882 [Multi-domain] Cd Length: 257 Bit Score: 39.95 E-value: 4.28e-03
|
||||||||
dermokine | cd21118 | dermokine; Dermokine, also known as epidermis-specific secreted protein SK30/SK89, is a ... |
834-971 | 6.31e-03 | ||||
dermokine; Dermokine, also known as epidermis-specific secreted protein SK30/SK89, is a skin-specific glycoprotein that may play a regulatory role in the crosstalk between barrier dysfunction and inflammation, and therefore play a role in inflammatory diseases such as psoriasis. Dermokine is one of the most highly expressed proteins in differentiating keratinocytes, found mainly in the spinous and granular layers of the epidermis, but also in the epithelia of the small intestine, macrophages of the lung, and endothelial cells of the lung. Mouse dermokine has been reported to be encoded by 22 exons, and its expression leads to alpha, beta, and gamma transcripts. Pssm-ID: 411053 [Multi-domain] Cd Length: 495 Bit Score: 40.37 E-value: 6.31e-03
|
||||||||
PRK13875 | PRK13875 | conjugal transfer protein TrbL; Provisional |
819-959 | 9.06e-03 | ||||
conjugal transfer protein TrbL; Provisional Pssm-ID: 237537 Cd Length: 440 Bit Score: 39.51 E-value: 9.06e-03
|
||||||||
PRK13875 | PRK13875 | conjugal transfer protein TrbL; Provisional |
844-971 | 9.96e-03 | ||||
conjugal transfer protein TrbL; Provisional Pssm-ID: 237537 Cd Length: 440 Bit Score: 39.51 E-value: 9.96e-03
|
||||||||
Blast search parameters | ||||
|