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Conserved domains on  [gi|961556603|gb|ALS55464|]
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RNA-dependent RNA polymerase, partial [Paramyxovirus PREDICT_PMV-18]

Protein Classification

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
Mononeg_RNA_pol super family cl15638
Mononegavirales RNA dependent RNA polymerase; Members of the Mononegavirales including the ...
1-176 4.72e-67

Mononegavirales RNA dependent RNA polymerase; Members of the Mononegavirales including the Paramyxoviridae, like other non-segmented negative strand RNA viruses, have an RNA-dependent RNA polymerase composed of two subunits, a large protein L and a phosphoprotein P. This is a protein family of the L protein. The L protein confers the RNA polymerase activity on the complex. The P protein acts as a transcription factor.


The actual alignment was detected with superfamily member pfam00946:

Pssm-ID: 395756  Cd Length: 1042  Bit Score: 220.29  E-value: 4.72e-67
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 961556603     1 QAIAITRRVHPNLPYNIKK-NLCTQLGQQYFKQLRHNMAGIGHNLKANETIVSSHFFIYSKRIYYDGVALSQSLKPLSRC 79
Cdd:pfam00946  690 QVIAVTYRVPSRLSYEEKKlEQAYRNARRIFKALRKVTSKLGLNLKLEETIISSDFFIYSKRIYYDGVILPQSLKRWSRV 769
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 961556603    80 VFWSETLVDETRSACSNISTSLSKAIEQGFDRWIGYSINVLKVI--------QQLCISLKFTINRSMTSDIVDPIYTNKT 151
Cdd:pfam00946  770 VPWSNDQIDDTRNSCSNISTSVARLIENGESPIPAYILNVLMTVfairllayHQLLISLGFSINKKLTRDILKPLESKIS 849
                          170       180
                   ....*....|....*....|....*
gi 961556603   152 WLATAMLLPSQLGGFNYMNISRLYV 176
Cdd:pfam00946  850 FLSLALLLPSSLGGLSFLSLSRLFY 874
 
Name Accession Description Interval E-value
Mononeg_RNA_pol pfam00946
Mononegavirales RNA dependent RNA polymerase; Members of the Mononegavirales including the ...
1-176 4.72e-67

Mononegavirales RNA dependent RNA polymerase; Members of the Mononegavirales including the Paramyxoviridae, like other non-segmented negative strand RNA viruses, have an RNA-dependent RNA polymerase composed of two subunits, a large protein L and a phosphoprotein P. This is a protein family of the L protein. The L protein confers the RNA polymerase activity on the complex. The P protein acts as a transcription factor.


Pssm-ID: 395756  Cd Length: 1042  Bit Score: 220.29  E-value: 4.72e-67
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 961556603     1 QAIAITRRVHPNLPYNIKK-NLCTQLGQQYFKQLRHNMAGIGHNLKANETIVSSHFFIYSKRIYYDGVALSQSLKPLSRC 79
Cdd:pfam00946  690 QVIAVTYRVPSRLSYEEKKlEQAYRNARRIFKALRKVTSKLGLNLKLEETIISSDFFIYSKRIYYDGVILPQSLKRWSRV 769
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 961556603    80 VFWSETLVDETRSACSNISTSLSKAIEQGFDRWIGYSINVLKVI--------QQLCISLKFTINRSMTSDIVDPIYTNKT 151
Cdd:pfam00946  770 VPWSNDQIDDTRNSCSNISTSVARLIENGESPIPAYILNVLMTVfairllayHQLLISLGFSINKKLTRDILKPLESKIS 849
                          170       180
                   ....*....|....*....|....*
gi 961556603   152 WLATAMLLPSQLGGFNYMNISRLYV 176
Cdd:pfam00946  850 FLSLALLLPSSLGGLSFLSLSRLFY 874
 
Name Accession Description Interval E-value
Mononeg_RNA_pol pfam00946
Mononegavirales RNA dependent RNA polymerase; Members of the Mononegavirales including the ...
1-176 4.72e-67

Mononegavirales RNA dependent RNA polymerase; Members of the Mononegavirales including the Paramyxoviridae, like other non-segmented negative strand RNA viruses, have an RNA-dependent RNA polymerase composed of two subunits, a large protein L and a phosphoprotein P. This is a protein family of the L protein. The L protein confers the RNA polymerase activity on the complex. The P protein acts as a transcription factor.


Pssm-ID: 395756  Cd Length: 1042  Bit Score: 220.29  E-value: 4.72e-67
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 961556603     1 QAIAITRRVHPNLPYNIKK-NLCTQLGQQYFKQLRHNMAGIGHNLKANETIVSSHFFIYSKRIYYDGVALSQSLKPLSRC 79
Cdd:pfam00946  690 QVIAVTYRVPSRLSYEEKKlEQAYRNARRIFKALRKVTSKLGLNLKLEETIISSDFFIYSKRIYYDGVILPQSLKRWSRV 769
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 961556603    80 VFWSETLVDETRSACSNISTSLSKAIEQGFDRWIGYSINVLKVI--------QQLCISLKFTINRSMTSDIVDPIYTNKT 151
Cdd:pfam00946  770 VPWSNDQIDDTRNSCSNISTSVARLIENGESPIPAYILNVLMTVfairllayHQLLISLGFSINKKLTRDILKPLESKIS 849
                          170       180
                   ....*....|....*....|....*
gi 961556603   152 WLATAMLLPSQLGGFNYMNISRLYV 176
Cdd:pfam00946  850 FLSLALLLPSSLGGLSFLSLSRLFY 874
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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