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Conserved domains on  [gi|960498886|gb|ALR85565|]
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NADH dehydrogenase subunit I, partial (mitochondrion) [Basutacris sp. 65_Basu_62]

Protein Classification

complex I subunit 1 family protein( domain architecture ID 103)

complex I subunit 1 family protein similar to NADH dehydrogenase subunit 1, which is the core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that functions in the transfer of electrons from NADH to the respiratory chain

EC:  7.1.1.-
Gene Ontology:  GO:0016655|GO:0016020
PubMed:  23417064|24059520
SCOP:  4005664

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PRK06076 super family cl00469
NADH-quinone oxidoreductase subunit NuoH;
6-104 6.27e-37

NADH-quinone oxidoreductase subunit NuoH;


The actual alignment was detected with superfamily member MTH00193:

Pssm-ID: 469782  Cd Length: 306  Bit Score: 126.04  E-value: 6.27e-37
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 960498886   6 MFMFILNFLLLLICVLISVAFLTLLERSVLGYIQIRKGPNKVGFVGIPQPLSDAIKLICSEQPIPIMSNYMFYYFSPVFS 85
Cdd:MTH00193   1 LMMMLINFLLLIICVLVSVAFLTLLERKVLGYIQIRKGPNKVGFMGILQPFSDAIKLFTKEQTYPLMSNYLLYYFSPVFS 80

                         90
                 ....*....|....*....
gi 960498886  86 LMISLFVWVIFPYLTYMCS 104
Cdd:MTH00193  81 LFLSLLIWLIYPYLFNLIS 99
 
Name Accession Description Interval E-value
ND1 MTH00193
NADH dehydrogenase subunit 1; Provisional
 6-104 6.27e-37

NADH dehydrogenase subunit 1; Provisional


Pssm-ID: 177241  Cd Length: 306  Bit Score: 126.04  E-value: 6.27e-37
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 960498886   6 MFMFILNFLLLLICVLISVAFLTLLERSVLGYIQIRKGPNKVGFVGIPQPLSDAIKLICSEQPIPIMSNYMFYYFSPVFS 85
Cdd:MTH00193   1 LMMMLINFLLLIICVLVSVAFLTLLERKVLGYIQIRKGPNKVGFMGILQPFSDAIKLFTKEQTYPLMSNYLLYYFSPVFS 80

                         90
                 ....*....|....*....
gi 960498886  86 LMISLFVWVIFPYLTYMCS 104
Cdd:MTH00193  81 LFLSLLIWLIYPYLFNLIS 99
NADHdh pfam00146
NADH dehydrogenase;
19-98 1.84e-17

NADH dehydrogenase;


Pssm-ID: 459690  Cd Length: 302  Bit Score: 74.82  E-value: 1.84e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 960498886   19 CVLISVAFLTLLERSVLGYIQIRKGPNKVGFVGIPQPLSDAIKLICSEQPIPIMSNYMFYYFSPVFSLMISLFVWVIFPY 98
Cdd:pfam00146   8 PLLLAVAFLTWAERKVLARMQRRIGPNRVGPFGLLQPFADALKLLFKEDIIPAGADKFLFLLAPIIAFIPALLAFAVIPF 87
 
Name Accession Description Interval E-value
ND1 MTH00193
NADH dehydrogenase subunit 1; Provisional
 6-104 6.27e-37

NADH dehydrogenase subunit 1; Provisional


Pssm-ID: 177241  Cd Length: 306  Bit Score: 126.04  E-value: 6.27e-37
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 960498886   6 MFMFILNFLLLLICVLISVAFLTLLERSVLGYIQIRKGPNKVGFVGIPQPLSDAIKLICSEQPIPIMSNYMFYYFSPVFS 85
Cdd:MTH00193   1 LMMMLINFLLLIICVLVSVAFLTLLERKVLGYIQIRKGPNKVGFMGILQPFSDAIKLFTKEQTYPLMSNYLLYYFSPVFS 80

                         90
                 ....*....|....*....
gi 960498886  86 LMISLFVWVIFPYLTYMCS 104
Cdd:MTH00193  81 LFLSLLIWLIYPYLFNLIS 99
ND1 MTH00225
NADH dehydrogenase subunit 1; Provisional
 8-101 1.02e-29

NADH dehydrogenase subunit 1; Provisional


Pssm-ID: 214465  Cd Length: 305  Bit Score: 107.43  E-value: 1.02e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 960498886   8 MFILNFLLLLICVLISVAFLTLLERSVLGYIQIRKGPNKVGFVGIPQPLSDAIKLICSEQPIPIMSNYMFYYFSPVFSLM 87
Cdd:MTH00225   2 SFLLKFLIMLICLLLSVAFYTLLERKVLGYIQLRKGPNKVGLMGLPQPFADALKLFTKEQTKPQLSNKLPYYIAPILSLI 81

                         90
                 ....*....|....
gi 960498886  88 ISLFVWVIFPYLTY 101
Cdd:MTH00225  82 LSLILWSLYPSMFS 95
ND1 MTH00143
NADH dehydrogenase subunit 1; Provisional
 19-99 1.18e-27

NADH dehydrogenase subunit 1; Provisional


Pssm-ID: 177201  Cd Length: 307  Bit Score: 102.26  E-value: 1.18e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 960498886  19 CVLISVAFLTLLERSVLGYIQIRKGPNKVGFVGIPQPLSDAIKLICSEQPIPIMSNYMFYYFSPVFSLMISLFVWVIFPY 98
Cdd:MTH00143  13 CVLLAVAFFTLLERKGLGYFQIRKGPNKVGLMGLPQPLADAVKLFTKEFVKPTMSNKFPFFLAPCLSLILALLLWQLYPS 92


                 .
gi 960498886  99 L 99
Cdd:MTH00143  93 Y 93
ND1 MTH00195
NADH dehydrogenase subunit 1; Provisional
 6-99 3.48e-22

NADH dehydrogenase subunit 1; Provisional


Pssm-ID: 214452  Cd Length: 307  Bit Score: 87.88  E-value: 3.48e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 960498886   6 MFMFILNFLLLLICVLISVAFLTLLERSVLGYIQIRKGPNKVGFVGIPQPLSDAIKLICSEQPIPIMSNYMFYYFSPVFS 85
Cdd:MTH00195   1 WMISVIHFLIQIVPVLLAVAFFTLLERKILGYIQLRKGPNKVGPYGLLQPIADAVKLFIKEPVKPSTSSLWLFFFAPVLA 80

                         90
                 ....*....|....
gi 960498886  86 LMISLFVWVIFPYL 99
Cdd:MTH00195  81 LALALILWVPIPSP 94
ND1 MTH00218
NADH dehydrogenase subunit 1; Provisional
 19-97 3.62e-21

NADH dehydrogenase subunit 1; Provisional


Pssm-ID: 214463  Cd Length: 311  Bit Score: 84.96  E-value: 3.62e-21
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 960498886  19 CVLISVAFLTLLERSVLGYIQIRKGPNKVGFVGIPQPLSDAIKLICSEQPIPIMSNYMFYYFSPVFSLMISLFVWVIFP 97
Cdd:MTH00218  14 PVLLAVAFLTLLERKVLGYMQLRKGPNVVGPYGLLQPIADGVKLFIKEPIRPSTSSPFLFLLAPILALTLALLLWMPLP 92
ND1 MTH00216
NADH dehydrogenase subunit 1; Provisional
 2-98 9.54e-21

NADH dehydrogenase subunit 1; Provisional


Pssm-ID: 164761  Cd Length: 327  Bit Score: 84.02  E-value: 9.54e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 960498886   2 MFYDMFMFILNFLLLLICVLISVAFLTLLERSVLGYIQIRKGPNKVGFVGIPQPLSDAIKLICSEQPIPIMSNYMFYYFS 81
Cdd:MTH00216   1 MMVFIIFYLIKILIIIVPLLIAVAYLTLAERKVLGYMQARKGPNVVGVYGLLQPFADGVKLFTKEMVIPHHANLFVYIVA 80

                         90
                 ....*....|....*..
gi 960498886  82 PVFSLMISLFVWVIFPY 98
Cdd:MTH00216  81 PVLSFTLALIVWGVIPY 97
ND1 MTH00010
NADH dehydrogenase subunit 1; Validated
 21-98 1.09e-20

NADH dehydrogenase subunit 1; Validated


Pssm-ID: 164586  Cd Length: 311  Bit Score: 83.68  E-value: 1.09e-20
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 960498886  21 LISVAFLTLLERSVLGYIQIRKGPNKVGFVGIPQPLSDAIKLICSEQPIPIMSNYMFYYFSPVFSLMISLFVWVIFPY 98
Cdd:MTH00010  17 LLAMAFYTLLERKALGYFQLRKGPNKVGLAGIPQPFADAIKLFTKEQTKPSPANITPFLGAPMMSLILALLLWSLYPH 94
ND1 MTH00111
NADH dehydrogenase subunit 1; Provisional
 20-97 1.85e-20

NADH dehydrogenase subunit 1; Provisional


Pssm-ID: 214422  Cd Length: 323  Bit Score: 83.41  E-value: 1.85e-20
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 960498886  20 VLISVAFLTLLERSVLGYIQIRKGPNKVGFVGIPQPLSDAIKLICSEQPIPIMSNYMFYYFSPVFSLMISLFVWVIFP 97
Cdd:MTH00111  18 ILIAVAFLTLLERKILGYMQLRKGPNIVGPFGLLQPIADGVKLFIKEPIRPSTSSPILFTLTPILALLLALTIWTPLP 95
ND1 MTH00054
NADH dehydrogenase subunit 1; Provisional
 6-98 8.31e-20

NADH dehydrogenase subunit 1; Provisional


Pssm-ID: 177127  Cd Length: 324  Bit Score: 81.70  E-value: 8.31e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 960498886   6 MFMFILNFLLLLICVLISVAFLTLLERSVLGYIQIRKGPNKVGFVGIPQPLSDAIKLICSEQPIPIMSNYMFYYFSPVFS 85
Cdd:MTH00054   1 MGIIIIKILAILVPLLISIAYLTLAERKVLGYIQCRKGPNVVGVYGLLQPLADGLKLFTKEIIIPNHANIFIYIMAPILS 80

                         90
                 ....*....|...
gi 960498886  86 LMISLFVWVIFPY 98
Cdd:MTH00054  81 LTLAFIAWGVIPY 93
ND1 MTH00040
NADH dehydrogenase subunit 1; Validated
 20-97 3.37e-19

NADH dehydrogenase subunit 1; Validated


Pssm-ID: 214409  Cd Length: 323  Bit Score: 80.02  E-value: 3.37e-19
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 960498886  20 VLISVAFLTLLERSVLGYIQIRKGPNKVGFVGIPQPLSDAIKLICSEQPIPIMSNYMFYYFSPVFSLMISLFVWVIFP 97
Cdd:MTH00040  17 VLLAVAFLTLVERKVLGYMQFRKGPNVVGPYGLLQPFADGLKLFIKETLKPSNASPYLFFFSPVLFLFLALLLWSLIP 94
ND1 MTH00071
NADH dehydrogenase subunit 1; Provisional
 20-97 4.97e-19

NADH dehydrogenase subunit 1; Provisional


Pssm-ID: 214418  Cd Length: 322  Bit Score: 79.28  E-value: 4.97e-19
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 960498886  20 VLISVAFLTLLERSVLGYIQIRKGPNKVGFVGIPQPLSDAIKLICSEQPIPIMSNYMFYYFSPVFSLMISLFVWVIFP 97
Cdd:MTH00071  18 VLLAVAFLTLVERKVLGYMQLRKGPNIVGPMGLLQPIADGLKLFIKEPIRPSTSSQILFILMPTMALTLALIIWTPLP 95
ND1 MTH00104
NADH dehydrogenase subunit 1; Provisional
 20-97 3.48e-18

NADH dehydrogenase subunit 1; Provisional


Pssm-ID: 177166  Cd Length: 318  Bit Score: 76.97  E-value: 3.48e-18
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 960498886  20 VLISVAFLTLLERSVLGYIQIRKGPNKVGFVGIPQPLSDAIKLICSEQPIPIMSNYMFYYFSPVFSLMISLFVWVIFP 97
Cdd:MTH00104  13 ILLAVAFLTLVERKVLGYMQLRKGPNIVGPYGLLQPFADAMKLFTKEPLRPLTSSTTMFIIAPILALTLALTMWIPLP 90
ND1 MTH00134
NADH dehydrogenase subunit 1; Provisional
 20-97 6.70e-18

NADH dehydrogenase subunit 1; Provisional


Pssm-ID: 177192  Cd Length: 324  Bit Score: 76.18  E-value: 6.70e-18
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 960498886  20 VLISVAFLTLLERSVLGYIQIRKGPNKVGFVGIPQPLSDAIKLICSEQPIPIMSNYMFYYFSPVFSLMISLFVWVIFP 97
Cdd:MTH00134  19 VLLAVAFLTLLERKVLGYMQLRKGPNIVGPYGLLQPIADGVKLFIKEPVRPSTSSPFLFLATPMLALTLALTLWAPMP 96
NADHdh pfam00146
NADH dehydrogenase;
19-98 1.84e-17

NADH dehydrogenase;


Pssm-ID: 459690  Cd Length: 302  Bit Score: 74.82  E-value: 1.84e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 960498886   19 CVLISVAFLTLLERSVLGYIQIRKGPNKVGFVGIPQPLSDAIKLICSEQPIPIMSNYMFYYFSPVFSLMISLFVWVIFPY 98
Cdd:pfam00146   8 PLLLAVAFLTWAERKVLARMQRRIGPNRVGPFGLLQPFADALKLLFKEDIIPAGADKFLFLLAPIIAFIPALLAFAVIPF 87
ND1 MTH00090
NADH dehydrogenase subunit 1; Provisional
 19-99 1.54e-14

NADH dehydrogenase subunit 1; Provisional


Pssm-ID: 177153  Cd Length: 284  Bit Score: 66.85  E-value: 1.54e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 960498886  19 CVLISVAFLTLLERSVLGYIQIRKGPNKVGFVGIPQPLSDAIKLICSEQPIPIMSNYMFYYFSPVFSLMISLFVWVIFPY 98
Cdd:MTH00090   8 FILQAIAFITLYERHLLGSSQNRLGPNKVSFMGVLQALLDGVKLLKKEQMLPLNSSDLSFLLVPGVSFVVMYLEWFVLPY 87


                 .
gi 960498886  99 L 99
Cdd:MTH00090  88 F 88
ND1 MTH00029
NADH dehydrogenase subunit 1; Provisional
 20-95 4.39e-14

NADH dehydrogenase subunit 1; Provisional


Pssm-ID: 177108  Cd Length: 343  Bit Score: 66.19  E-value: 4.39e-14
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 960498886  20 VLISVAFLTLLERSVLGYIQIRKGPNKVGFVGIPQPLSDAIKLICSEQPIPIMSNYMFYYFSPVFSLMISLFVWVI 95
Cdd:MTH00029  20 LLLSVAYLTLAERKVLGLMQNRKGPAIVGPWGLVQPIADGVKLLTKELIIPSQANKFLYYIAPIISFTLAILAWAI 95
PRK06076 PRK06076
NADH-quinone oxidoreductase subunit NuoH;
20-98 1.76e-13

NADH-quinone oxidoreductase subunit NuoH;


Pssm-ID: 235692  Cd Length: 322  Bit Score: 64.06  E-value: 1.76e-13
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 960498886  20 VLISVAFLTLLERSVLGYIQIRKGPNKVGFVGIPQPLSDAIKLICSEQPIPIMSNYMFYYFSPVFSLMISLFVWVIFPY 98
Cdd:PRK06076  23 VLLCVAFLIWFERKVLARMQLRYGPNRVGPFGLLQLVADGIKLLFKEDIIPAGADKVLFLLAPVIAFIPAFLAWAVIPF 101
ND1 MTH00058
NADH dehydrogenase subunit 1; Provisional
 20-64 2.37e-09

NADH dehydrogenase subunit 1; Provisional


Pssm-ID: 177130  Cd Length: 293  Bit Score: 52.62  E-value: 2.37e-09
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*
gi 960498886  20 VLISVAFLTLLERSVLGYIQIRKGPNKVGFVGIPQPLSDAIKLIC 64
Cdd:MTH00058  14 ILLLVAFFILGERKILGYIQLRKGPNKVGIVGLLQSFADLLKLVV 58
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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