NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|955537576|ref|XP_014650475|]
View 

PREDICTED: ZW10 interactor [Ceratotherium simum simum]

Protein Classification

ZW10 interactor( domain architecture ID 12173870)

ZW10 interactor (ZWINT) is involved in kinetochore formation and spindle checkpoint activity. It interacts with ZW10, another kinetochore protein, possibly regulating the association between ZW10 and kinetochore.

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
Zwint pfam15556
ZW10 interactor; This family of proteins is found in eukaryotes. Proteins in this family are ...
 29-268 7.95e-127

ZW10 interactor; This family of proteins is found in eukaryotes. Proteins in this family are typically between 127 and 281 amino acids in length.


:

Pssm-ID: 464766 [Multi-domain]  Cd Length: 252  Bit Score: 362.76  E-value: 7.95e-127
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 955537576   29 QEEAELPAQILAEFVMDSRKKDKLLCSQLQVVDFLQNFLAQEDIARGLDPLVSEDTSRQKAIAAKEQWKELKATYQEHVE 108
Cdd:pfam15556   1 QEEAELPAQILAEFVMDSRKKDKLLCSQLQVVDFLQNFLAQEDTAQGLDPLASEDTSRQKAIAAKEQWKELKATYQEHVE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 955537576  109 AITSALTQALPKVEEAQRKRAQLQEALEQLQAKKQVAMEKLRIAQKQWQLQQEKHLQHLVEVSAEVRERQTGMQQELERL 188
Cdd:pfam15556  81 AITSALTQALPKMEEAQRKRAQLQEALEQLQAKKQMAMEKLRTAQKQWQLQQEKHLQHLAEVSAEVRERQTGTQQELERL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 955537576  189 YQELGTLKQEAGQERDKLQRHQTFLQLLNTLQGKLLFPEAEAELPQELDLPERKPQQLTQPHEHNTGDTMGRDEDVSSKV 268
Cdd:pfam15556 161 YQELGTLKQQAGQERDKLQRHQTFLQLLYTLQGKLLFPEAEAELPQKLDLPEDKSQQLTQPQEQNTGDTMGRDRAVSSKA 240
 
Name Accession Description Interval E-value
Zwint pfam15556
ZW10 interactor; This family of proteins is found in eukaryotes. Proteins in this family are ...
 29-268 7.95e-127

ZW10 interactor; This family of proteins is found in eukaryotes. Proteins in this family are typically between 127 and 281 amino acids in length.


Pssm-ID: 464766 [Multi-domain]  Cd Length: 252  Bit Score: 362.76  E-value: 7.95e-127
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 955537576   29 QEEAELPAQILAEFVMDSRKKDKLLCSQLQVVDFLQNFLAQEDIARGLDPLVSEDTSRQKAIAAKEQWKELKATYQEHVE 108
Cdd:pfam15556   1 QEEAELPAQILAEFVMDSRKKDKLLCSQLQVVDFLQNFLAQEDTAQGLDPLASEDTSRQKAIAAKEQWKELKATYQEHVE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 955537576  109 AITSALTQALPKVEEAQRKRAQLQEALEQLQAKKQVAMEKLRIAQKQWQLQQEKHLQHLVEVSAEVRERQTGMQQELERL 188
Cdd:pfam15556  81 AITSALTQALPKMEEAQRKRAQLQEALEQLQAKKQMAMEKLRTAQKQWQLQQEKHLQHLAEVSAEVRERQTGTQQELERL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 955537576  189 YQELGTLKQEAGQERDKLQRHQTFLQLLNTLQGKLLFPEAEAELPQELDLPERKPQQLTQPHEHNTGDTMGRDEDVSSKV 268
Cdd:pfam15556 161 YQELGTLKQQAGQERDKLQRHQTFLQLLYTLQGKLLFPEAEAELPQKLDLPEDKSQQLTQPQEQNTGDTMGRDRAVSSKA 240
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
97-237 3.84e-06

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 48.37  E-value: 3.84e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 955537576   97 KELKATYQEHVEAITSALTQALPKVEEAQRKRAQLQEALEQLQAKKQVAMEKL-------RIAQKQWQLQQ----EKHLQ 165
Cdd:COG4913   609 RAKLAALEAELAELEEELAEAEERLEALEAELDALQERREALQRLAEYSWDEIdvasaerEIAELEAELERldasSDDLA 688

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 955537576  166 HLVEVSAEVRERQTGMQQELERLYQELGTLKQEAGQERDKLQRHQTFLQLLNTLQGKLLFPEAEAELPQELD 237
Cdd:COG4913   689 ALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRALLEERFAAALG 760
mukB PRK04863
chromosome partition protein MukB;
91-199 3.41e-05

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 45.72  E-value: 3.41e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 955537576   91 AAKEQWKEL--KATYQEHVEAITSALTQALPKVEEAQRKRAQLQEALEQLQaKKQVAMEKLRIAQKQWQLQQEKHLQHLV 168
Cdd:PRK04863  493 EAWDVARELlrRLREQRHLAEQLQQLRMRLSELEQRLRQQQRAERLLAEFC-KRLGKNLDDEDELEQLQEELEARLESLS 571

                          90       100       110
                  ....*....|....*....|....*....|.
gi 955537576  169 EVSAEVRERQTGMQQELERLYQELGTLKQEA 199
Cdd:PRK04863  572 ESVSEARERRMALRQQLEQLQARIQRLAARA 602
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 70-248 5.44e-04

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 41.58  E-value: 5.44e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 955537576    70 EDIA----RGLDPLVSEDTSRQKAIAAKEQWKELKAT--------YQEHVEAITSALTQALPKVEEAQRKRAQLQEALEQ 137
Cdd:TIGR02168  192 EDILneleRQLKSLERQAEKAERYKELKAELRELELAllvlrleeLREELEELQEELKEAEEELEELTAELQELEEKLEE 271

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 955537576   138 LQAKKQVAMEKLRIAQKQWQLQQ------EKHLQHLVEVSAEVRERQTGMQQELERLYQELGTLKQEAGQERDKLQRHQT 211
Cdd:TIGR02168  272 LRLEVSELEEEIEELQKELYALAneisrlEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKE 351

                          170       180       190
                   ....*....|....*....|....*....|....*..
gi 955537576   212 FLQLLntlqgKLLFPEAEAELPQELDLPERKPQQLTQ 248
Cdd:TIGR02168  352 ELESL-----EAELEELEAELEELESRLEELEEQLET 383
 
Name Accession Description Interval E-value
Zwint pfam15556
ZW10 interactor; This family of proteins is found in eukaryotes. Proteins in this family are ...
 29-268 7.95e-127

ZW10 interactor; This family of proteins is found in eukaryotes. Proteins in this family are typically between 127 and 281 amino acids in length.


Pssm-ID: 464766 [Multi-domain]  Cd Length: 252  Bit Score: 362.76  E-value: 7.95e-127
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 955537576   29 QEEAELPAQILAEFVMDSRKKDKLLCSQLQVVDFLQNFLAQEDIARGLDPLVSEDTSRQKAIAAKEQWKELKATYQEHVE 108
Cdd:pfam15556   1 QEEAELPAQILAEFVMDSRKKDKLLCSQLQVVDFLQNFLAQEDTAQGLDPLASEDTSRQKAIAAKEQWKELKATYQEHVE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 955537576  109 AITSALTQALPKVEEAQRKRAQLQEALEQLQAKKQVAMEKLRIAQKQWQLQQEKHLQHLVEVSAEVRERQTGMQQELERL 188
Cdd:pfam15556  81 AITSALTQALPKMEEAQRKRAQLQEALEQLQAKKQMAMEKLRTAQKQWQLQQEKHLQHLAEVSAEVRERQTGTQQELERL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 955537576  189 YQELGTLKQEAGQERDKLQRHQTFLQLLNTLQGKLLFPEAEAELPQELDLPERKPQQLTQPHEHNTGDTMGRDEDVSSKV 268
Cdd:pfam15556 161 YQELGTLKQQAGQERDKLQRHQTFLQLLYTLQGKLLFPEAEAELPQKLDLPEDKSQQLTQPQEQNTGDTMGRDRAVSSKA 240
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
97-237 3.84e-06

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 48.37  E-value: 3.84e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 955537576   97 KELKATYQEHVEAITSALTQALPKVEEAQRKRAQLQEALEQLQAKKQVAMEKL-------RIAQKQWQLQQ----EKHLQ 165
Cdd:COG4913   609 RAKLAALEAELAELEEELAEAEERLEALEAELDALQERREALQRLAEYSWDEIdvasaerEIAELEAELERldasSDDLA 688

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 955537576  166 HLVEVSAEVRERQTGMQQELERLYQELGTLKQEAGQERDKLQRHQTFLQLLNTLQGKLLFPEAEAELPQELD 237
Cdd:COG4913   689 ALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRALLEERFAAALG 760
mukB PRK04863
chromosome partition protein MukB;
91-199 3.41e-05

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 45.72  E-value: 3.41e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 955537576   91 AAKEQWKEL--KATYQEHVEAITSALTQALPKVEEAQRKRAQLQEALEQLQaKKQVAMEKLRIAQKQWQLQQEKHLQHLV 168
Cdd:PRK04863  493 EAWDVARELlrRLREQRHLAEQLQQLRMRLSELEQRLRQQQRAERLLAEFC-KRLGKNLDDEDELEQLQEELEARLESLS 571

                          90       100       110
                  ....*....|....*....|....*....|.
gi 955537576  169 EVSAEVRERQTGMQQELERLYQELGTLKQEA 199
Cdd:PRK04863  572 ESVSEARERRMALRQQLEQLQARIQRLAARA 602
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
69-225 3.53e-05

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 45.14  E-value: 3.53e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 955537576  69 QEDIARGLDPLVSEDTSRQKAIAAKEQWKELKATyqehvEAITSALTQALPKVEEAQRKRAQLQEALEQLQAKKQVAMEK 148
Cdd:COG4717  104 LEELEAELEELREELEKLEKLLQLLPLYQELEAL-----EAELAELPERLEELEERLEELRELEEELEELEAELAELQEE 178

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 955537576 149 LRIAQKQWQLQQEKHLQHLVEVSAEVRERQTGMQQELERLYQELGTLKQEAGQERDKLQRHQTFLQLLNTLQGKLLF 225
Cdd:COG4717  179 LEELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQEELEELEEELEQLENELEAAALEERLKEARLLLLIA 255
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 80-248 6.60e-05

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 44.56  E-value: 6.60e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 955537576   80 VSEDTSRQKAIAAKEQWKELKATYQEhVEAITSALTQALPKVEEAQRKRAQLQEaLEQLQAKKQVAMEKLRIAQKQWQLQ 159
Cdd:COG3096   488 VERSQAWQTARELLRRYRSQQALAQR-LQQLRAQLAELEQRLRQQQNAERLLEE-FCQRIGQQLDAAEELEELLAELEAQ 565

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 955537576  160 QEKHLQHLvevsAEVRERQTGMQQELERLYQELGTLKQEAGQER---DKLQR-----HQTFL---QLLNTLQGKLlfpEA 228
Cdd:COG3096   566 LEELEEQA----AEAVEQRSELRQQLEQLRARIKELAARAPAWLaaqDALERlreqsGEALAdsqEVTAAMQQLL---ER 638

                         170       180
                  ....*....|....*....|
gi 955537576  229 EAELPQELDLPERKPQQLTQ 248
Cdd:COG3096   639 EREATVERDELAARKQALES 658
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 64-238 7.06e-05

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 44.54  E-value: 7.06e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 955537576  64 QNFLAQEDIARGLDPLVSEDTSRQKAIAAKEQWKELKATYQEHVEAITSALTQALPKVEEAQRKRAQLQEALEQLQAKKQ 143
Cdd:COG1196  289 EEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALL 368

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 955537576 144 VAMEKLRIAQKQWQLQQEKHLQHLVEVS------AEVRERQTGMQQELERLYQELGTLKQEAGQERDKLQRHQTFLQLLN 217
Cdd:COG1196  369 EAEAELAEAEEELEELAEELLEALRAAAelaaqlEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAA 448

                        170       180
                 ....*....|....*....|.
gi 955537576 218 TLQGKLLFPEAEAELPQELDL 238
Cdd:COG1196  449 EEEAELEEEEEALLELLAELL 469
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 88-216 1.35e-04

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 43.77  E-value: 1.35e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 955537576  88 KAIAAKEQWKELKATYQEHVEAITSALTQAlpkvEEAQRKRAQLQEALEQLQAKKQVAMEKLRIAQKQWQLQQEKhLQHL 167
Cdd:COG1196  226 EAELLLLKLRELEAELEELEAELEELEAEL----EELEAELAELEAELEELRLELEELELELEEAQAEEYELLAE-LARL 300

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*....
gi 955537576 168 VEVSAEVRERQTGMQQELERLYQELGTLKQEAGQERDKLQRHQTFLQLL 216
Cdd:COG1196  301 EQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEA 349
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 70-248 5.44e-04

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 41.58  E-value: 5.44e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 955537576    70 EDIA----RGLDPLVSEDTSRQKAIAAKEQWKELKAT--------YQEHVEAITSALTQALPKVEEAQRKRAQLQEALEQ 137
Cdd:TIGR02168  192 EDILneleRQLKSLERQAEKAERYKELKAELRELELAllvlrleeLREELEELQEELKEAEEELEELTAELQELEEKLEE 271

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 955537576   138 LQAKKQVAMEKLRIAQKQWQLQQ------EKHLQHLVEVSAEVRERQTGMQQELERLYQELGTLKQEAGQERDKLQRHQT 211
Cdd:TIGR02168  272 LRLEVSELEEEIEELQKELYALAneisrlEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKE 351

                          170       180       190
                   ....*....|....*....|....*....|....*..
gi 955537576   212 FLQLLntlqgKLLFPEAEAELPQELDLPERKPQQLTQ 248
Cdd:TIGR02168  352 ELESL-----EAELEELEAELEELESRLEELEEQLET 383
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 68-246 6.88e-04

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 41.58  E-value: 6.88e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 955537576    68 AQEDIARGLDPLVSEDTSRQKAIAAKEQWKELKATYQEHVEAITSALTQALPKVEEAQRKRAQLQEALEQLQAKkqVAME 147
Cdd:TIGR02168  314 LERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSK--VAQL 391

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 955537576   148 KLRIAQKQWQLQQ-EKHLQHLvevsAEVRERQTGMQQELERLYQELGTLKQEAGQERDKLQRHQTFLQLLNTLQGKLLFP 226
Cdd:TIGR02168  392 ELQIASLNNEIERlEARLERL----EDRRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELR 467

                          170       180
                   ....*....|....*....|
gi 955537576   227 EAEAELPQELDLPERKPQQL 246
Cdd:TIGR02168  468 EELEEAEQALDAAERELAQL 487
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 69-248 1.88e-03

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 40.04  E-value: 1.88e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 955537576    69 QEDIARGLDPLvseDTSRQKAIAAKEQWKELKATYQEHVEAITSALTQALPKVEEAQRKRAQL------QEALEQLQAKK 142
Cdd:TIGR02168  788 EAQIEQLKEEL---KALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIeelsedIESLAAEIEEL 864

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 955537576   143 QVAMEKLRIAQKQWQLQQEKHLQHLVEVSAEVRERQTGMQ------QELERLYQELGTLKQEAGQERDKLQrhQTFLQLL 216
Cdd:TIGR02168  865 EELIEELESELEALLNERASLEEALALLRSELEELSEELReleskrSELRRELEELREKLAQLELRLEGLE--VRIDNLQ 942

                          170       180       190
                   ....*....|....*....|....*....|....
gi 955537576   217 NTL--QGKLLFPEAEAELPQELDLPERKPQQLTQ 248
Cdd:TIGR02168  943 ERLseEYSLTLEEAEALENKIEDDEEEARRRLKR 976
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
96-223 2.16e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 39.90  E-value: 2.16e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 955537576   96 WKELKATYQEHVEAITsALTQALPKVEEAQRKRAQLQEALEQLQAKKQVAMEKLRIAQKQWQLQQEKHLQHLVEVSAEVR 175
Cdd:COG4913   663 VASAEREIAELEAELE-RLDASSDDLAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAED 741

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*....
gi 955537576  176 ERQTGMQQELERLYQELGTLKQEAgQERDKLQRHQTFLQ-LLNTLQGKL 223
Cdd:COG4913   742 LARLELRALLEERFAAALGDAVER-ELRENLEERIDALRaRLNRAEEEL 789
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 91-207 3.74e-03

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 39.15  E-value: 3.74e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 955537576  91 AAKEQWKELKATYQEH---VEAITSALTQALPKVEEAQRKRAQLQEALEQLQAKKQVAMEKLRIAQKQWQLQQEKhLQHL 167
Cdd:COG1196  236 ELEAELEELEAELEELeaeLEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEER-RREL 314

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|
gi 955537576 168 VEVSAEVRERQTGMQQELERLYQELGTLKQEAGQERDKLQ 207
Cdd:COG1196  315 EERLEELEEELAELEEELEELEEELEELEEELEEAEEELE 354
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
82-198 4.09e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 39.13  E-value: 4.09e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 955537576   82 EDTSRQKAIAAKEQWKELKATYQEH----VEAITSALTQALPKVEEAQRKRAQLQEALEQLQAKKQVAMEKLRIAQKQWQ 157
Cdd:COG4913   311 LERLEARLDALREELDELEAQIRGNggdrLEQLEREIERLERELEERERRRARLEALLAALGLPLPASAEEFAALRAEAA 390

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|.
gi 955537576  158 LQQEKhlqhLVEVSAEVRERQTGMQQELERLYQELGTLKQE 198
Cdd:COG4913   391 ALLEA----LEEELEALEEALAEAEAALRDLRRELRELEAE 427
PTZ00269 PTZ00269
variant surface glycoprotein; Provisional
 132-262 4.44e-03

variant surface glycoprotein; Provisional


Pssm-ID: 140295 [Multi-domain]  Cd Length: 472  Bit Score: 38.74  E-value: 4.44e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 955537576 132 QEALEQLQAKKQVAMEKLRIAQKQWQLQQEKHLQHLVEVS-------AEVRERQTGMQ----QELERLYQELGTLKQEAG 200
Cdd:PTZ00269  40 ERGLKHIKLAKQVTQEALKIGVRYLEVAGEEEAAELAKAQedsctkkMEDRKRNCGLYktfwEEAQEALKERTARSEAPH 119

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 955537576 201 QERDKLQRHQTFLQLLNTLQGKLLFPEAEAELPQ-ELDLPERKPQQLTQPHEHNTGDTMGRDE 262
Cdd:PTZ00269 120 RKRNSLQYHTAEEIKKKVMEVADIYHEVEAESLSgKVEKMEEQLNQALYGMEYFTEEIKGGDD 182
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 47-235 4.77e-03

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 38.80  E-value: 4.77e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 955537576    47 RKKDKLLCSQLQVVDFLQNFLAQEDIARGLDPLVSEdtsRQKAIAAKEQWKELkATYQEHVEAITSALTQALPKVEEAQR 126
Cdd:TIGR00618  246 TQKREAQEEQLKKQQLLKQLRARIEELRAQEAVLEE---TQERINRARKAAPL-AAHIKAVTQIEQQAQRIHTELQSKMR 321

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 955537576   127 KRAQLQEALEQLQAKKQVAMEKLRIAQkQWQlQQEKHLQHLVEVSAEVRE---RQTGMQQELERLYQELGTLKQE---AG 200
Cdd:TIGR00618  322 SRAKLLMKRAAHVKQQSSIEEQRRLLQ-TLH-SQEIHIRDAHEVATSIREiscQQHTLTQHIHTLQQQKTTLTQKlqsLC 399

                          170       180       190
                   ....*....|....*....|....*....|....*....
gi 955537576   201 QERDKLQRHQ----TFLQLLNTLQGKLLFPEAEAELPQE 235
Cdd:TIGR00618  400 KELDILQREQatidTRTSAFRDLQGQLAHAKKQQELQQR 438
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
76-210 5.14e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 38.74  E-value: 5.14e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 955537576   76 LDPLVSEDTSRQKAIAAKEQWKELKATYQehVEAITSALTQALPKVEEAQRKRAQLQEALEQLQAKKQVAMEKLRIAQKQ 155
Cdd:COG4913   254 LEPIRELAERYAAARERLAELEYLRAALR--LWFAQRRLELLEAELEELRAELARLEAELERLEARLDALREELDELEAQ 331

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 955537576  156 WQLQQEKHLQHLVEVSAEVRERQTGMQQELERLYQELGTLKQEAGQERDKLQRHQ 210
Cdd:COG4913   332 IRGNGGDRLEQLEREIERLERELEERERRRARLEALLAALGLPLPASAEEFAALR 386
HEC1 COG5185
Chromosome segregation protein NDC80, interacts with SMC proteins [Cell cycle control, cell ...
 83-270 9.55e-03

Chromosome segregation protein NDC80, interacts with SMC proteins [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 444066 [Multi-domain]  Cd Length: 594  Bit Score: 37.63  E-value: 9.55e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 955537576  83 DTSRQKAIAAKEQWKELKatyQEHVEAITSALTQALPKVEEAQRKRAQLQEALEQLQAKKQVAMEKL-RIAQKQWQLQQE 161
Cdd:COG5185  387 ESTKESLDEIPQNQRGYA---QEILATLEDTLKAADRQIEELQRQIEQATSSNEEVSKLLNELISELnKVMREADEESQS 463

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 955537576 162 KHLQHLVEVSAEVRERQTGMQQELERLYQELGTLKQEAGQERDKLQRH-QTFLQLLNtlQGKLLFPEAEAELPQELDLPE 240
Cdd:COG5185  464 RLEEAYDEINRSVRSKKEDLNEELTQIESRVSTLKATLEKLRAKLERQlEGVRSKLD--QVAESLKDFMRARGYAHILAL 541

                        170       180       190
                 ....*....|....*....|....*....|
gi 955537576 241 RKPQQLTQPHEHNTGDTMGRDEDVSSKVNE 270
Cdd:COG5185  542 ENLIPASELIQASNAKTDGQAANLRTAVID 571
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH