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Conserved domains on  [gi|953245173|ref|YP_009180345|]
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NADH dehydrogenase subunit 4L (mitochondrion) [Aldabrachelys gigantea]

Protein Classification

NADH-ubiquinone oxidoreductase subunit 4L( domain architecture ID 10009576)

NADH-ubiquinone oxidoreductase subunit 4L (ND4L) is core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ND4L MTH00126
NADH dehydrogenase subunit 4L; Provisional
 1-98 3.63e-42

NADH dehydrogenase subunit 4L; Provisional


:

Pssm-ID: 177185  Cd Length: 98  Bit Score: 133.17  E-value: 3.63e-42
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 953245173  1 MTLTHFNCYSAFIISITGLSLHRTHLVSTLLCLEGMMLSLFIALSMWPIQLQTPSLMLAPMLMLAFSACEAGMGLSLLVA 80
Cdd:MTH00126  1 MTPVHFSFSSAFILGLMGLAFHRTHLLSALLCLEGMMLSLFIALSLWALQLESTSFSAAPMLLLAFSACEASAGLALLVA 80

                        90
                ....*....|....*...
gi 953245173 81 SSRTHGSDHLQNLNLLQC 98
Cdd:MTH00126 81 TARTHGTDRLQNLNLLQC 98
 
Name Accession Description Interval E-value
ND4L MTH00126
NADH dehydrogenase subunit 4L; Provisional
 1-98 3.63e-42

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177185  Cd Length: 98  Bit Score: 133.17  E-value: 3.63e-42
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 953245173  1 MTLTHFNCYSAFIISITGLSLHRTHLVSTLLCLEGMMLSLFIALSMWPIQLQTPSLMLAPMLMLAFSACEAGMGLSLLVA 80
Cdd:MTH00126  1 MTPVHFSFSSAFILGLMGLAFHRTHLLSALLCLEGMMLSLFIALSLWALQLESTSFSAAPMLLLAFSACEASAGLALLVA 80

                        90
                ....*....|....*...
gi 953245173 81 SSRTHGSDHLQNLNLLQC 98
Cdd:MTH00126 81 TARTHGTDRLQNLNLLQC 98
Oxidored_q2 pfam00420
NADH-ubiquinone/plastoquinone oxidoreductase chain 4L;
11-98 2.44e-15

NADH-ubiquinone/plastoquinone oxidoreductase chain 4L;


Pssm-ID: 425672  Cd Length: 95  Bit Score: 64.89  E-value: 2.44e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 953245173  11 AFIISITGLsLHRTHLVSTLLCLEGMMLSLFIALSMWPIQLQTPSLMLAPMLMLAFSACEAGMGLSLLVASSRTHGSDHL 90
Cdd:pfam00420  9 LFLIGLYGL-LLRRNLLRVLLSLELMLNAVNLALVLFGRLTADPLPQALILTAIVIAAAEAAVGLALLVRIYRTHGTDDV 87


                 ....*...
gi 953245173  91 QNLNLLQC 98
Cdd:pfam00420 88 DSLNLLKG 95
 
Name Accession Description Interval E-value
ND4L MTH00126
NADH dehydrogenase subunit 4L; Provisional
 1-98 3.63e-42

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177185  Cd Length: 98  Bit Score: 133.17  E-value: 3.63e-42
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 953245173  1 MTLTHFNCYSAFIISITGLSLHRTHLVSTLLCLEGMMLSLFIALSMWPIQLQTPSLMLAPMLMLAFSACEAGMGLSLLVA 80
Cdd:MTH00126  1 MTPVHFSFSSAFILGLMGLAFHRTHLLSALLCLEGMMLSLFIALSLWALQLESTSFSAAPMLLLAFSACEASAGLALLVA 80

                        90
                ....*....|....*...
gi 953245173 81 SSRTHGSDHLQNLNLLQC 98
Cdd:MTH00126 81 TARTHGTDRLQNLNLLQC 98
ND4L MTH00125
NADH dehydrogenase subunit 4L; Provisional
 1-98 1.06e-39

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177184  Cd Length: 98  Bit Score: 126.88  E-value: 1.06e-39
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 953245173  1 MTLTHFNCYSAFIISITGLSLHRTHLVSTLLCLEGMMLSLFIALSMWPIQLQTPSLMLAPMLMLAFSACEAGMGLSLLVA 80
Cdd:MTH00125  1 MTPTHFSLYTAFMLSLLGLSFHRTHLMSALLCLESMMLSLFIMLSLWPITTQTPSFTPMPIILLTFSACEAGTGLALLVA 80

                        90
                ....*....|....*...
gi 953245173 81 SSRTHGSDHLQNLNLLQC 98
Cdd:MTH00125 81 TTRTHGSDHLKNLNLLQC 98
ND4L MTH00067
NADH dehydrogenase subunit 4L; Provisional
 1-98 1.50e-38

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177139  Cd Length: 98  Bit Score: 123.95  E-value: 1.50e-38
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 953245173  1 MTLTHFNCYSAFIISITGLSLHRTHLVSTLLCLEGMMLSLFIALSMWPIQLQTPSLMLAPMLMLAFSACEAGMGLSLLVA 80
Cdd:MTH00067  1 MSPTYFTFYSAFLLGLMGLAFHRTHLLSALLCLEGMMLSLFIALSLWSTQFESLSYFSLPMFMLTFSACEASTGLALMVA 80

                        90
                ....*....|....*...
gi 953245173 81 SSRTHGSDHLQNLNLLQC 98
Cdd:MTH00067 81 TTRTHGTDHLKNLNLLQC 98
ND4L MTH00107
NADH dehydrogenase subunit 4L; Provisional
 1-98 2.83e-27

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177169  Cd Length: 98  Bit Score: 95.38  E-value: 2.83e-27
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 953245173  1 MTLTHFNCYSAFIISITGLSLHRTHLVSTLLCLEGMMLSLFIALSMWPIQLQTPSLMLAPMLMLAFSACEAGMGLSLLVA 80
Cdd:MTH00107  1 MSLIYMNIMLAFTISLLGLLMYRSHLMSSLLCLEGMMLSLFIMATLTILNTHFTLASMMPIILLVFAACEAAVGLALLVM 80

                        90
                ....*....|....*...
gi 953245173 81 SSRTHGSDHLQNLNLLQC 98
Cdd:MTH00107 81 VSNTYGTDYVQNLNLLQC 98
ND4L MTH00181
NADH dehydrogenase subunit 4L; Provisional
 10-96 1.30e-19

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 214450  Cd Length: 93  Bit Score: 75.75  E-value: 1.30e-19
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 953245173 10 SAFIISITGLSLHRTHLVSTLLCLEGMMLSLFIALSMWPIQLQTPSLMLAPMLMLAFSACEAGMGLSLLVASSRTHGSDH 89
Cdd:MTH00181  7 SAFILLLLGLSLYKTHLLSLLLCLEGMMLFLFLLLALFSLLSSSSSMLMFGLILLTFSACEAVLGLSLLVATNRTHGSDH 86


                ....*..
gi 953245173 90 LQNLNLL 96
Cdd:MTH00181 87 LLKFNLL 93
Oxidored_q2 pfam00420
NADH-ubiquinone/plastoquinone oxidoreductase chain 4L;
11-98 2.44e-15

NADH-ubiquinone/plastoquinone oxidoreductase chain 4L;


Pssm-ID: 425672  Cd Length: 95  Bit Score: 64.89  E-value: 2.44e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 953245173  11 AFIISITGLsLHRTHLVSTLLCLEGMMLSLFIALSMWPIQLQTPSLMLAPMLMLAFSACEAGMGLSLLVASSRTHGSDHL 90
Cdd:pfam00420  9 LFLIGLYGL-LLRRNLLRVLLSLELMLNAVNLALVLFGRLTADPLPQALILTAIVIAAAEAAVGLALLVRIYRTHGTDDV 87


                 ....*...
gi 953245173  91 QNLNLLQC 98
Cdd:pfam00420 88 DSLNLLKG 95
ND4L MTH00043
NADH dehydrogenase subunit 4L; Validated
 1-97 2.54e-14

NADH dehydrogenase subunit 4L; Validated


Pssm-ID: 214410  Cd Length: 98  Bit Score: 62.63  E-value: 2.54e-14
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 953245173  1 MTLTHFNCYSAFIISITGLSLHRTHLVSTLLCLEGMMLSLFIALSMWPIQLQTPSLMLAPMLMLAFSACEAGMGLSLLVA 80
Cdd:MTH00043  1 MNIILIIILSSFFLGLLGILINRLHLLSILLCLELLLISLFLNISIWSLNYGNFSNLSFSLLLLTLSACEASIGLSLMVL 80

                        90
                ....*....|....*..
gi 953245173 81 SSRTHGSDHLQNLNLLQ 97
Cdd:MTH00043 81 LSRNHNSDLVASLNLLQ 97
ND4L MTH00188
NADH dehydrogenase subunit 4L; Provisional
 6-98 3.95e-10

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177237  Cd Length: 97  Bit Score: 51.90  E-value: 3.95e-10
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 953245173  6 FNCYSAFIISITGLSLHRTHLVSTLLCLEGMMLSLFIALSMWPiqLQTPSLMLAPMLMLAFSACEAGMGLSLLVASSRTH 85
Cdd:MTH00188  7 LVILLFVVLGLFTFLLNRKHLLMLLLSLEAIMLSLFWFLLVGL--SYMEKELYLSLVLLTFAACEASVGLALLVSLIRSH 84

                        90
                ....*....|...
gi 953245173 86 GSDHLQNLNLLQC 98
Cdd:MTH00188 85 GSDYVSSLNLIKC 97
ND4L MTH00162
NADH dehydrogenase subunit 4L; Provisional
 12-92 3.35e-08

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177218  Cd Length: 89  Bit Score: 46.69  E-value: 3.35e-08
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 953245173 12 FIISITGLSLHRTHLVSTLLCLEGMMLSLFIALSMWPIQLQTPSLMLapMLMLAFSACEAGMGLSLLVASSRTHGSDHLQ 91
Cdd:MTH00162 11 FFSGLLVFLSKRKHLLLMLLSLEFMVLSLFFLLFLYLSFFNYELYFL--LFFLTFSVCEGALGLSILVSMIRSHGNDYFS 88


                .
gi 953245173 92 N 92
Cdd:MTH00162 89 S 89
ND4L MTH00013
NADH dehydrogenase subunit 4L; Validated
 12-98 1.75e-07

NADH dehydrogenase subunit 4L; Validated


Pssm-ID: 133655  Cd Length: 97  Bit Score: 45.13  E-value: 1.75e-07
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 953245173 12 FIISITGLSLHRTHLVSTLLCLEGMMLSLFIALSMWPIQLQTPSLMLApMLMLAFSACEAGMGLSLLVASSRTHGSDHLQ 91
Cdd:MTH00013 12 PFISMFNLSLQRKHLLMSLLSLEAMILSLALFIPLSLMFANQVNGMLA-IVLLTFGACEASLGLSLLVLMTRSYGNDMLK 90


                ....*..
gi 953245173 92 NLNLLQC 98
Cdd:MTH00013 91 SLTSNKC 97
ND4L MTH00149
NADH dehydrogenase subunit 4L; Provisional
 12-98 3.90e-07

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 214434  Cd Length: 97  Bit Score: 44.07  E-value: 3.90e-07
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 953245173 12 FIISITGLSLHRTHLVSTLLCLEGMMLSLFIalSMWPIQLQTPSLMLAPMLMLAFSACEAGMGLSLLVASSRTHGSDHLQ 91
Cdd:MTH00149 13 FLMGVFALLFQYKHLLSILLSLEALMLSLLV--MMFSSSGLISFSSYLFLIILTFGACEASLGLSLLVSLIRLHGNDYVS 90


                ....*..
gi 953245173 92 NLNLLQC 98
Cdd:MTH00149 91 SLSSLKF 97
ND4L MTH00180
NADH dehydrogenase subunit 4L; Provisional
 12-97 8.57e-05

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177231  Cd Length: 99  Bit Score: 38.09  E-value: 8.57e-05
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 953245173 12 FIISITGLSLHRTHLVSTLLCLEGMMLSLFIALSMWPIQLQTPSLMLAPMLMLAFSACEAGMGLSLLVASSRTHGSDHLQ 91
Cdd:MTH00180 13 FILGVLGIVLNRSNLIIMLMSIELMLLAISLLFLINSVAIDNLIGQIFTIMILTVAAAESAIGLAILVAYYRIRGTIAVK 92


                ....*.
gi 953245173 92 NLNLLQ 97
Cdd:MTH00180 93 SLNLLR 98
ND4L MTH00001
NADH dehydrogenase subunit 4L; Provisional
 12-97 6.77e-04

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177099  Cd Length: 99  Bit Score: 35.81  E-value: 6.77e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 953245173 12 FIISITGLSLHRTHLVSTLLCLEGMMLSLFIALSMWPIQLQTPSLMLAPMLMLAFSACEAGMGLSLLVASSRTHGSDHLQ 91
Cdd:MTH00001 13 FLLGIWGIILNRGHFIIMLVSIELVLLSTFFLFLINSIEIDLLIEQIFTIMGLTIAAAESAIGLAIMVAYYRIRGTISLK 92


                ....*.
gi 953245173 92 NLNLLQ 97
Cdd:MTH00001 93 SLNSLR 98
ND4 MTH00127
NADH dehydrogenase subunit 4; Provisional
 67-98 2.72e-03

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 177186 [Multi-domain]  Cd Length: 459  Bit Score: 35.32  E-value: 2.72e-03
                         10        20        30
                 ....*....|....*....|....*....|..
gi 953245173  67 SACEAGMGLSLLVASSRTHGSDHLQNLNLLQC 98
Cdd:MTH00127 401 TLITAGYSLYMFLMTQRGPLPDHIIALNPSHT 432
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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