|
Name |
Accession |
Description |
Interval |
E-value |
| FepA |
COG4771 |
Outer membrane receptor for ferrienterochelin and colicins [Inorganic ion transport and ... |
70-734 |
1.91e-60 |
|
Outer membrane receptor for ferrienterochelin and colicins [Inorganic ion transport and metabolism];
Pssm-ID: 443803 [Multi-domain] Cd Length: 612 Bit Score: 215.11 E-value: 1.91e-60
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 952994189 70 ALNREVSSASKKGESVFESPLSTTVITKEEIKLTGATTYEELFRLVPGMIVRQESN--GNYDIHIRGndnLPPGNfshfs 147
Cdd:COG4771 26 ELEEVVVTATRTEQSLSDAPASVSVITAEEIEKLGATDLADALRLLPGVSVTRSGGrgGSSGISIRG---LGGDR----- 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 952994189 148 enmmTLVMVDGRIVYNYINGGTiWESLPVAMSDIERIEIIRGASSALYGPNAVSGVINIITRTPDKDGaqvHGDVKVGNS 227
Cdd:COG4771 98 ----VLVLIDGVPVNNPALGGG-GDLSYIPPDDIERIEVIRGPASALYGSDAIGGVINIITKKPTDEL---EGSVSLGYG 169
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 952994189 228 DTYIGNFSL---LNKISEDFGFKVSGAYDFRDRFQDDFYEYASGTYvpadsltsmfgnqlhasspdaelAKKAFNANAGL 304
Cdd:COG4771 170 SNGNGTYSGslsLGGPGDKLSFLLSGSYRDRDGYLDYRNGGFVGNS-----------------------GYERYNLNAKL 226
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 952994189 305 FYEPSNDLSMSLNGGWQSSESQSMFFENLATPFGIRESETGYVDYKASAYG----------FQAQVNYLTGRQN----LH 370
Cdd:COG4771 227 GYRLSDNHRLSLSGGYSRQDRDGGPPTLGDTEISSDNAGDRDTTTDRGNYSlryngdlgdnLDLSLYYSRTDRDstngSL 306
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 952994189 371 EKMIKPVIEYDMNFLSANLEYDLVLNDlgigELTVRPGFNYQLANYDDKTYVEKVDTvgdldrgllngekSLETISGSMR 450
Cdd:COG4771 307 GGSTGSFSDSDDTTYGLELDLTYPLGG----NHTLTLGAEYRYDDLDSSSFLGGADA-------------SRDTYGLFAQ 369
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 952994189 451 IDYKPISELRLIAALRADKYNVPD---DIYMSWQFVGAYNINSKHLLRATYSRANRGSFMGNAYANFQNPLGPNyyqfYV 527
Cdd:COG4771 370 DEWKLTDKLTLTAGLRYDYYSTFGasnYTAFSPRLGLRYDLSDNLTLRASYGRGFRAPSLAELYGSGTGTPGRY----VL 445
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 952994189 528 GDENLNLLTQDLIEVGYRGILTNY-LQVDFEAFRTKTTDFDalfpkVYEIDGGITYDQWYYQNIDmESEQLGATLNVAVQ 606
Cdd:COG4771 446 GNPDLKPETSDNYELGLEYRLGNGgLSLSLTGFYTDIKDLI-----VLVPVGPGPGDVLQYENVG-KARTYGLELELKYR 519
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 952994189 607 PLDNLIIKVFGTYQNTKLthvlkdisefytinfitgqqsmtpyseldESSFEDGNNDWTPGFYGGAMINYTPVQKFNINA 686
Cdd:COG4771 520 LGKGLTLTASYTYLDSKI-----------------------------DDGDTGEPLPNVPPHKANLGLDYRLPKWWLLLL 570
|
650 660 670 680
....*....|....*....|....*....|....*....|....*...
gi 952994189 687 SLYYYDKQTYSRYYFAYPTHktmeasLDPNVILNAKVAYRISNNASVY 734
Cdd:COG4771 571 LTRYYGGRYVTPPSGRLEGY------TPGYTLLDLRASYKLTKNLTLS 612
|
|
| ligand_gated_channel |
cd01347 |
TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) ... |
91-742 |
2.36e-29 |
|
TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel. Energy (proton-motive force) and TonB-dependent conformational alteration of channel (parts of plug, and loops 7 and 8) allow passage of ligand. FepA residues 12-18 form the TonB box, which mediates the interaction with the TonB-containing inner membrane complex. TonB preferentially interacts with ligand-bound receptors. Transport thru the channel may resemble passage thru an air lock. In this model, ligand binding leads to closure of the extracellular end of pore, then a TonB-mediated signal facillitates opening of the interior side of pore, deforming the N-terminal plug and allowing passage of the ligand to the periplasm. Such a mechanism would prevent the free diffusion of small molecules thru the pore.
Pssm-ID: 238657 [Multi-domain] Cd Length: 635 Bit Score: 124.10 E-value: 2.36e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 952994189 91 STTVITKEEIKLTGATTYEELFRLVPGM-IVRQESNGNYDIHIRGndnLPPGNfshfsenmmTLVMVDGRIVYNYiNGGT 169
Cdd:cd01347 1 SVSVITAEDIEKQPATSLADLLRRIPGVsVTRGGGGGGSTISIRG---FGPDR---------TLVLVDGLPLASS-NYGR 67
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 952994189 170 IWESLPVAMSDIERIEIIRGASSALYGPNAVSGVINIITRTPdkdGAQVHGDVKVG-NSDTYI----GNFSLLNKISED- 243
Cdd:cd01347 68 GVDLNTIPPELIERVEVLKGPSSALYGSGAIGGVVNIITKRP---TDEFGGSVTAGyGSDNSGssggGGFDVSGALADDg 144
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 952994189 244 -FGFKVSGAYDFRDRFQDDFYEYASGTYVpADSLTSMFGNQLhasSPDAELakkafNANAGLFYEPSNDLSMSLNGGWQS 322
Cdd:cd01347 145 aFGARLYGAYRDGDGTIDGDGQADDSDEE-RYNVAGKLDWRP---DDDTRL-----TLDAGYQDQDADGPGGTLPANGTG 215
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 952994189 323 SESQSMFFENLATPFGIRESeTGYVDYKASAYGFQAQVNYLTGRQNLH--EKMIKPVIEYDMNFLSANLEYDLVLNDLGI 400
Cdd:cd01347 216 SSLGGGPSSNTNGDRDWDYR-DRYRKRASLGLEHDLNDTGWTLRANLSysYTDNDGDPLILNGGNNAAGGDLGRSGYSSE 294
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 952994189 401 GELTVRPGFNYQLANYDDKTYVEKVdTVGDLDRGLLNGEKSLET-ISGSMRIDYKpiseLRLIAALRADKYNVPDDIYM- 478
Cdd:cd01347 295 RDTTQLGFDAGLNAPFGTGPVAHTL-TLGVEYRREELDEKQTALyAQDTIELTDD----LTLTLGLRYDHYDQDSKDTIa 369
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 952994189 479 ------------SWQFVGAYNINSKHLLRATYSRANRGSFMGNAYANfqnplGPNYYQFYVGDENLNLLTQDLIEVGYRG 546
Cdd:cd01347 370 ggttakksyshwSPSLGLVYKLTDGLSLYASYSQGFRAPSLGELYGG-----GSHGGTAAVGNPNLKPEKSKQYELGLKY 444
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 952994189 547 ILTNYLQVDFEAFRTKTTDFdALFPKVYEIDGGITYdqwYYQNIDMESEqlGATLNVAVQPLDNLIIKVFGTYQNTKLTH 626
Cdd:cd01347 445 DPGDGLTLSAALFRIDIKNE-IVSTPTNTGLGLVTV---YVNGGKARIR--GVELEASYDLTDGLGLTGSYTYTDTEVKR 518
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 952994189 627 VLKDIsefytinfitgqqsmtpyseldessfEDGNNDWTPGFYGGAMINYT-PVQKFNINASLYYYDKQTysRYYFAYPT 705
Cdd:cd01347 519 TDGAT--------------------------TGNRLPGIPKHTANLGLDYElPDEGLTAGGGVRYRGKQY--ADTANGNN 570
|
650 660 670
....*....|....*....|....*....|....*..
gi 952994189 706 HKTmeasLDPNVILNAKVAYRISNNASVYLSGQNILD 742
Cdd:cd01347 571 TVK----VPGYTLVDLSASYQFTKNLTLRLGVNNLFD 603
|
|
| Plug |
pfam07715 |
TonB-dependent Receptor Plug Domain; The Plug domain has been shown to be an independently ... |
84-203 |
5.04e-23 |
|
TonB-dependent Receptor Plug Domain; The Plug domain has been shown to be an independently folding subunit of the TonB-dependent receptors. It acts as the channel gate, blocking the pore until the channel is bound by ligand. At this point it under goes conformational changes opens the channel.
Pssm-ID: 462243 [Multi-domain] Cd Length: 107 Bit Score: 94.26 E-value: 5.04e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 952994189 84 SVFESPLSTTVITKEEIKLTGATTYEELFRLVPGMIVRQESNGNYD-IHIRGndnlppgnfshFSENMmTLVMVDGRIVY 162
Cdd:pfam07715 1 DLRDTPGSVSVVTAEDIEDQGATNLADALRGVPGVSVSSGGGGGGSsISIRG-----------FGSNR-VLVLVDGVPLN 68
|
90 100 110 120
....*....|....*....|....*....|....*....|.
gi 952994189 163 NYINGGTIWESLPvaMSDIERIEIIRGASSALYGPNAVSGV 203
Cdd:pfam07715 69 SGGGGSVDLNSID--PEDIERVEVLKGPASALYGSGAIGGV 107
|
|
| TonB-siderophor |
TIGR01783 |
TonB-dependent siderophore receptor; This subfamily model encompasses a wide variety of ... |
87-537 |
8.81e-21 |
|
TonB-dependent siderophore receptor; This subfamily model encompasses a wide variety of TonB-dependent outer membrane siderophore receptors. It has no overlap with TonB receptors known to transport other substances, but is likely incomplete due to lack of characterizations. It is likely that genuine siderophore receptors will be identified which score below the noise cutoff to this model at which point the model should be updated. [Transport and binding proteins, Cations and iron carrying compounds, Transport and binding proteins, Porins]
Pssm-ID: 273805 [Multi-domain] Cd Length: 651 Bit Score: 97.48 E-value: 8.81e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 952994189 87 ESPLSTTVITKEEIKLTGATTYEELFRLVPGmIVRQESNGNYD---IHIRGndnlppgnfshFSENMMTL-VMVDGRIVY 162
Cdd:TIGR01783 1 DIPQSVSVITRQELEDQQAGSLSEALQRVPG-VVVGGSGGTTQfgnITIRG-----------FGLEVDIDnVYLDGVPLL 68
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 952994189 163 NYINggtiweSLPVAMSDIERIEIIRGASSALYGPNAVSGVINIITRTPDKDGAQvHGDVKVGNSDTYIGNFSLLNKISE 242
Cdd:TIGR01783 69 SRGN------LAIVDPAMVERVEVLRGPASLLYGGSAPGGVINIVTKRPQDEPKG-SVTFGAGTRSGYRTAFDLGGPLGA 141
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 952994189 243 DFGFKVSGAYDFRDRfqDDFYEYAS--------GTYVPADSLT------------SMFGNQLHASSPDAELAKKAFNANA 302
Cdd:TIGR01783 142 DGTFRGRLNGARQDG--DSFYDGAGeetrlgatATDWQLDDRTllrlgayyqkerDRGGYGGLPASGGTSGRDLSSDRYL 219
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 952994189 303 GlfyEPSNDLSMSLNGGWQSSESQSMFFENLATPFGIRESETGYVDYKASAYGFQAQVNYLTGRQNLHEKMIKPVI---E 379
Cdd:TIGR01783 220 G---TSSNRNYDDREYLSYGLSLEYQFNDVWTGKQNLRYSYFDTDSNQVQASGYSSDGGLFGRSLTVVNVKQDRVQidaG 296
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 952994189 380 YDMNFLSANLEYDLVlndLGIGELTVRPGFNYQLANYDDKTYVEKVDTVGD-------LDRGLLNGEKSLETISGSMRID 452
Cdd:TIGR01783 297 LDGEFETGPIEHDLL---LGVSYGQRTTNRFNNTGYPSDNIYSLTATSSARtdigdspKDRALSSTTKALNGVALQRILL 373
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 952994189 453 ykpISELRLIAALRADKYNV------------PDDIYMSWQFVGAYNINSKHLLRATYSRANRGSFMGNAYANFQN-PLG 519
Cdd:TIGR01783 374 ---ADKWTLTLGGRYDSVDVksnngvagstgkRDDSQFTPSLGVAYKPTDDWSLYASYAESFKPGGYYPKGAGNSGdILE 450
|
490 500
....*....|....*....|.
gi 952994189 520 P---NYYQFYVGDENLNLLTQ 537
Cdd:TIGR01783 451 PekgKNYELGVRYDLGDSLLA 471
|
|
| PRK13483 |
PRK13483 |
ligand-gated channel protein; |
63-326 |
2.33e-19 |
|
ligand-gated channel protein;
Pssm-ID: 184080 [Multi-domain] Cd Length: 660 Bit Score: 92.92 E-value: 2.33e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 952994189 63 TDELLDLALNREVSSASKKGESVFESPLSTTVITKEEIK------LTGAttyeelFRLVPGMIVRQESNGNyDIHIRGNd 136
Cdd:PRK13483 25 AQAAPDKTMETVVVTASGYEQQIRDAPASISVITREDLEnrfyrdLTDA------LLDVPGVVVTGGGDRT-DISLRGM- 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 952994189 137 nlpPGNFshfsenmmTLVMVDGR------IVYNYINGGTIWESLPvAMSDIERIEIIRGASSALYGPNAVSGVINIITRt 210
Cdd:PRK13483 97 ---GSQY--------TLILVDGKrqssreTRPNSDGPGVEQAWTP-PLAAIERIEVIRGPMSSLYGSDAIGGVINIITR- 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 952994189 211 pdKDGAQVHGDVKVG-----NSDT---YIGNFSLLNKISED-FGFKVSGAYDFRDrfQDDFYEYASGTyvPADSLTSMFG 281
Cdd:PRK13483 164 --KVPNEWQGEVRLDttlqeNSDSgnvYQANFFVNGPLIKDlLGLQLYGQYTQRE--EDDIEGGYRDK--DARSLTAKLA 237
|
250 260 270 280
....*....|....*....|....*....|....*....|....*....
gi 952994189 282 ---NQLHASSPDAELAKKAFNANAGLFYEP-SNDLSMSLNGGWQSSESQ 326
Cdd:PRK13483 238 ltpNEDHDIMLEVGTSNQERDSTVGKTVAPlAPGESCGRRGCPESSTTE 286
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| FepA |
COG4771 |
Outer membrane receptor for ferrienterochelin and colicins [Inorganic ion transport and ... |
70-734 |
1.91e-60 |
|
Outer membrane receptor for ferrienterochelin and colicins [Inorganic ion transport and metabolism];
Pssm-ID: 443803 [Multi-domain] Cd Length: 612 Bit Score: 215.11 E-value: 1.91e-60
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 952994189 70 ALNREVSSASKKGESVFESPLSTTVITKEEIKLTGATTYEELFRLVPGMIVRQESN--GNYDIHIRGndnLPPGNfshfs 147
Cdd:COG4771 26 ELEEVVVTATRTEQSLSDAPASVSVITAEEIEKLGATDLADALRLLPGVSVTRSGGrgGSSGISIRG---LGGDR----- 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 952994189 148 enmmTLVMVDGRIVYNYINGGTiWESLPVAMSDIERIEIIRGASSALYGPNAVSGVINIITRTPDKDGaqvHGDVKVGNS 227
Cdd:COG4771 98 ----VLVLIDGVPVNNPALGGG-GDLSYIPPDDIERIEVIRGPASALYGSDAIGGVINIITKKPTDEL---EGSVSLGYG 169
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 952994189 228 DTYIGNFSL---LNKISEDFGFKVSGAYDFRDRFQDDFYEYASGTYvpadsltsmfgnqlhasspdaelAKKAFNANAGL 304
Cdd:COG4771 170 SNGNGTYSGslsLGGPGDKLSFLLSGSYRDRDGYLDYRNGGFVGNS-----------------------GYERYNLNAKL 226
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 952994189 305 FYEPSNDLSMSLNGGWQSSESQSMFFENLATPFGIRESETGYVDYKASAYG----------FQAQVNYLTGRQN----LH 370
Cdd:COG4771 227 GYRLSDNHRLSLSGGYSRQDRDGGPPTLGDTEISSDNAGDRDTTTDRGNYSlryngdlgdnLDLSLYYSRTDRDstngSL 306
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 952994189 371 EKMIKPVIEYDMNFLSANLEYDLVLNDlgigELTVRPGFNYQLANYDDKTYVEKVDTvgdldrgllngekSLETISGSMR 450
Cdd:COG4771 307 GGSTGSFSDSDDTTYGLELDLTYPLGG----NHTLTLGAEYRYDDLDSSSFLGGADA-------------SRDTYGLFAQ 369
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 952994189 451 IDYKPISELRLIAALRADKYNVPD---DIYMSWQFVGAYNINSKHLLRATYSRANRGSFMGNAYANFQNPLGPNyyqfYV 527
Cdd:COG4771 370 DEWKLTDKLTLTAGLRYDYYSTFGasnYTAFSPRLGLRYDLSDNLTLRASYGRGFRAPSLAELYGSGTGTPGRY----VL 445
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 952994189 528 GDENLNLLTQDLIEVGYRGILTNY-LQVDFEAFRTKTTDFDalfpkVYEIDGGITYDQWYYQNIDmESEQLGATLNVAVQ 606
Cdd:COG4771 446 GNPDLKPETSDNYELGLEYRLGNGgLSLSLTGFYTDIKDLI-----VLVPVGPGPGDVLQYENVG-KARTYGLELELKYR 519
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 952994189 607 PLDNLIIKVFGTYQNTKLthvlkdisefytinfitgqqsmtpyseldESSFEDGNNDWTPGFYGGAMINYTPVQKFNINA 686
Cdd:COG4771 520 LGKGLTLTASYTYLDSKI-----------------------------DDGDTGEPLPNVPPHKANLGLDYRLPKWWLLLL 570
|
650 660 670 680
....*....|....*....|....*....|....*....|....*...
gi 952994189 687 SLYYYDKQTYSRYYFAYPTHktmeasLDPNVILNAKVAYRISNNASVY 734
Cdd:COG4771 571 LTRYYGGRYVTPPSGRLEGY------TPGYTLLDLRASYKLTKNLTLS 612
|
|
| CirA |
COG1629 |
Outer membrane receptor protein, Fe transport [Inorganic ion transport and metabolism]; |
77-745 |
2.73e-52 |
|
Outer membrane receptor protein, Fe transport [Inorganic ion transport and metabolism];
Pssm-ID: 441236 [Multi-domain] Cd Length: 644 Bit Score: 192.74 E-value: 2.73e-52
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 952994189 77 SASKKGESVFESPLSTTVITKEEIKLTGATTYEELFRLVPGMIVRQESNGNYDIHIRGNDNLPPGnfshfsenmmTLVMV 156
Cdd:COG1629 7 TATRTDESLQDVPGSVSVISREQLEDQPATDLGDLLRRVPGVSVTSAGGGAGQISIRGFGGGGNR----------VLVLV 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 952994189 157 DGRIVYNYINGGTIWESLPvaMSDIERIEIIRGASSALYGPNAVSGVINIITRTPdKDGAQVHGDVKVGNSDTYIGNFSL 236
Cdd:COG1629 77 DGVPLNDPSGGDGGLSYID--PEDIERVEVLRGPSSALYGSGALGGVINIVTKKP-KDGKGGEVSASYGSYGTYRASLSL 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 952994189 237 LNKiSEDFGFKVSGAYdfrdRFQDDFYEYASGtyvpadsltsmfgnqlhasspdaelakKAFNANAGLFYEPSNDLSMSL 316
Cdd:COG1629 154 SGG-NGKLAYRLSASY----RDSDGYRDNSDS---------------------------DRYNLRAKLGYQLGDDTRLTL 201
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 952994189 317 NGGWQSSESQS-------MFFENLATPFGIRESETGYVDYKASAYG-------------FQAQVNYLTGRQNLHEKMIKP 376
Cdd:COG1629 202 SASYSDSDQDSpgyltlaALRPRGAMDDGTNPYSNDTDDNTRDRYSlsleyehlgdglkLSASAYYRYDDTDLDSDFTPT 281
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 952994189 377 VI--------EYDMNFLSANLEYDLVLNDLGIGELTVrpGFNYQLANYDDKTYVEKVDTVGDLDRGLLNGEK-SLETISG 447
Cdd:COG1629 282 PAdggtleqtDFDNRTYGLELRLTYDLGFGGKHTLLV--GLDYQRQDLDGSGYPLDLGSGSLPTLTSGADDDgTTTSLAL 359
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 952994189 448 SMRIDYKPISELRLIAALRADKYNVPDDIYM---------------SWQFVGAYNINSKHLLRATYSRANRGSFMGNAYA 512
Cdd:COG1629 360 YAQDTYKLTDKLTLTAGLRYDYVSYDVDDTVtgtdsasgsrsysafSPSLGLTYQLSPNLSLYASYSRGFRAPTFGELYA 439
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 952994189 513 NFQNPlgpnyyqFYVGDENLNLLTQDLIEVGYRG-ILTNYLQVDFEAFRTKTTDFdaLFPKVYEIDGGItydQWYYQNID 591
Cdd:COG1629 440 NGTDP-------YSVGNPDLKPETSTNYELGLRYrLLDGRLSLSLALFYSDVDNE--ILSVPLPNDSGF---STYYTNAG 507
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 952994189 592 mESEQLGATLNVAVQPLDNLIIKVFGTYQNTKlthvlkdisefytinfitgqqsmtpYSELDESSFEDGNNDW--TPGFY 669
Cdd:COG1629 508 -KARSYGVELELSYQLTPGLSLNASYSYTDAK-------------------------FDDDTDGSADLDGNRLpgVPPLT 561
|
650 660 670 680 690 700 710
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 952994189 670 GGAMINYTPVQKFNINASLYYYDKQtysrYYFAYPTHKTMEASldpnVILNAKVAYRISNNASVYLSGQNILDHNN 745
Cdd:COG1629 562 ANLGLTYEFPGGWSLGLGVRYVGDR----YLDDANTQGAPGGY----TLVDLGAGYRFGDNLTLSLGVDNLFDKKY 629
|
|
| BtuB |
COG4206 |
Outer membrane cobalamin receptor protein BtuB [Coenzyme transport and metabolism]; |
75-391 |
5.82e-37 |
|
Outer membrane cobalamin receptor protein BtuB [Coenzyme transport and metabolism];
Pssm-ID: 443355 [Multi-domain] Cd Length: 276 Bit Score: 140.01 E-value: 5.82e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 952994189 75 VSSASKKGESVFESPLSTTVITKEEIKLTGATTYEELFRLVPGMIVRQ--ESNGNYDIHIRGndnlppGNFSHfsenmmT 152
Cdd:COG4206 2 VVTATRLEQSKSDLTGSVTVIDAEELERSGATSLADALRRVPGVQVSSsgGPGSAASISIRG------LGSNQ------T 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 952994189 153 LVMVDGRIVYNYINGGTIWESLPVamSDIERIEIIRGASSALYGPNAVSGVINIITRTPdKDGAQVHGDVKVGNSDTYIG 232
Cdd:COG4206 70 LVLIDGVPLNDPSLGGVDLSLIPP--DDIERIEVLKGAASALYGSDAIGGVINITTKKG-KKGFKGSVSASYGSFGTRRL 146
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 952994189 233 NFSLLNKiSEDFGFKVSGAYdfrdrFQDDFYEYASGTYVPADsltsmfgnqlhasspdaelAKKAFNANAGLFYEPSNDL 312
Cdd:COG4206 147 SASLSGG-AGKFSYSLSASY-----RRSDGYRYNDPDLRNND-------------------GYENTSLNARLGYKLGDNG 201
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 952994189 313 SMSLNGGWQSSESQsmFFENLATPFGIRESetGYVDYKASAYGFQAQVNYLTGRQNLHEKMIKPVIEYDMNFLSANLEY 391
Cdd:COG4206 202 SLSLSGGYSDSERG--YPGAVGSDRNLRLS--LSLEYKLSDGWSLLLLAYYYYDRDYEDGGGDSAGTSNTDGARAGLSY 276
|
|
| FhuE |
COG4773 |
Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid [Inorganic ion ... |
72-742 |
6.48e-30 |
|
Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid [Inorganic ion transport and metabolism];
Pssm-ID: 443805 [Multi-domain] Cd Length: 692 Bit Score: 126.16 E-value: 6.48e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 952994189 72 NREVSSASKKGESVFESPLSTTVITKEEIKLTGATTYEELFRLVPGMIVRQESNGNYD-IHIRGndnlppgnfshFSenm 150
Cdd:COG4773 49 AKSSSTATKLDTPLRETPQSVSVVTRQLIEDQGATTLDDALRNVPGVTVSSYDGGGRDsFSIRG-----------FS--- 114
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 952994189 151 MTLVMVDGRIVYNYINGgtiweslPVAMSDIERIEIIRGASSALYGPNAVSGVINIITRTPDKDgAQVHGDVKVGNSDTY 230
Cdd:COG4773 115 IDNYLRDGLPLGGFGGG-------QPDTANLERVEVLKGPAGLLYGAGSPGGLVNLVTKRPTAE-PQGEVSLSAGSWDTY 186
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 952994189 231 IGNFSLLNKISED--FGFKVSGAYD----FRDRFQDD-FYEYASGTYVPADSLT-------------------SMFGNQL 284
Cdd:COG4773 187 RATADVGGPLNEDgtLRYRLNAAYEdgdsFRDGVDNRrTLIAPSLDWDLTDDTTltlgaeyqdddstgdrgflPLDGTLL 266
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 952994189 285 H------ASSPDAELAKKAFNANAGLFYEPSNDLSMSLNGGWQSSESQSmffeNLATPFGIRESETGYVDYKASAYGFqa 358
Cdd:COG4773 267 DlprstnLGEPWDYYDTETTTLFAELEHRFNDDWSLRANARYSDSDRDG----RSAYAYGAPDAATGTLTRYASARDG-- 340
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 952994189 359 qvnyltgrqnlhekmikpviEYDMNFLSANLEYDLVLndLGIG-ELTVrpGFNYQLANYDDKTYVEKVDTVGDLDRGLLN 437
Cdd:COG4773 341 --------------------DSRSDSLDANLNGKFET--GGLEhTLLV--GADYSRYDSDSDSATAGTINIYNPVYGNLP 396
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 952994189 438 gEKSLETISGSMRIDY---------KPISELRLIAALRADKYNVPDDIYMSWQ-----------FVGA-YNINSKHLLRA 496
Cdd:COG4773 397 -EPDFDASDTDTTTRQtglyaqdqiSLTDRLSLLLGGRYDWYETDSTNRLGGSttsyddsaftpRAGLvYDLTPGLSLYA 475
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 952994189 497 TYSRanrgSFMGNAYANFQ-NPLGPnyyqfyvgdenlnlLTQDLIEVGYRGILTNY-LQVDFEAFRTKTTDF---DALFP 571
Cdd:COG4773 476 SYSE----SFEPQSGADNNgNPLDP--------------ETGKQYEAGVKGELFDGrLNATLAVFDITQKNVattDPDNP 537
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 952994189 572 KVYEIDGGITYDqwyyqnidmeseqlGATLNVAVQPLDNLIIKVFGTYQNTKLThvlkdisefytinfitgqqsmtpyse 651
Cdd:COG4773 538 NFYVQVGEVRSR--------------GVELELSGELTPGLNLIAGYTYTDAKIT-------------------------- 577
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 952994189 652 lDESSFEDGN-NDWTPGFYGGAMINYT----PVQKFNINASLYYYDKqtysRYYFAYPTHKtmeasLDPNVILNAKVAYR 726
Cdd:COG4773 578 -KDADALEGKrLTNVPRHTASLWTTYRfpsgALKGLGLGGGVRYVGE----RYGDAANTFT-----LPSYTLVDAGARYD 647
|
730
....*....|....*.
gi 952994189 727 ISNNASVYLSGQNILD 742
Cdd:COG4773 648 LGKNWTLQLNVNNLFD 663
|
|
| ligand_gated_channel |
cd01347 |
TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) ... |
91-742 |
2.36e-29 |
|
TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel. Energy (proton-motive force) and TonB-dependent conformational alteration of channel (parts of plug, and loops 7 and 8) allow passage of ligand. FepA residues 12-18 form the TonB box, which mediates the interaction with the TonB-containing inner membrane complex. TonB preferentially interacts with ligand-bound receptors. Transport thru the channel may resemble passage thru an air lock. In this model, ligand binding leads to closure of the extracellular end of pore, then a TonB-mediated signal facillitates opening of the interior side of pore, deforming the N-terminal plug and allowing passage of the ligand to the periplasm. Such a mechanism would prevent the free diffusion of small molecules thru the pore.
Pssm-ID: 238657 [Multi-domain] Cd Length: 635 Bit Score: 124.10 E-value: 2.36e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 952994189 91 STTVITKEEIKLTGATTYEELFRLVPGM-IVRQESNGNYDIHIRGndnLPPGNfshfsenmmTLVMVDGRIVYNYiNGGT 169
Cdd:cd01347 1 SVSVITAEDIEKQPATSLADLLRRIPGVsVTRGGGGGGSTISIRG---FGPDR---------TLVLVDGLPLASS-NYGR 67
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 952994189 170 IWESLPVAMSDIERIEIIRGASSALYGPNAVSGVINIITRTPdkdGAQVHGDVKVG-NSDTYI----GNFSLLNKISED- 243
Cdd:cd01347 68 GVDLNTIPPELIERVEVLKGPSSALYGSGAIGGVVNIITKRP---TDEFGGSVTAGyGSDNSGssggGGFDVSGALADDg 144
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 952994189 244 -FGFKVSGAYDFRDRFQDDFYEYASGTYVpADSLTSMFGNQLhasSPDAELakkafNANAGLFYEPSNDLSMSLNGGWQS 322
Cdd:cd01347 145 aFGARLYGAYRDGDGTIDGDGQADDSDEE-RYNVAGKLDWRP---DDDTRL-----TLDAGYQDQDADGPGGTLPANGTG 215
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 952994189 323 SESQSMFFENLATPFGIRESeTGYVDYKASAYGFQAQVNYLTGRQNLH--EKMIKPVIEYDMNFLSANLEYDLVLNDLGI 400
Cdd:cd01347 216 SSLGGGPSSNTNGDRDWDYR-DRYRKRASLGLEHDLNDTGWTLRANLSysYTDNDGDPLILNGGNNAAGGDLGRSGYSSE 294
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 952994189 401 GELTVRPGFNYQLANYDDKTYVEKVdTVGDLDRGLLNGEKSLET-ISGSMRIDYKpiseLRLIAALRADKYNVPDDIYM- 478
Cdd:cd01347 295 RDTTQLGFDAGLNAPFGTGPVAHTL-TLGVEYRREELDEKQTALyAQDTIELTDD----LTLTLGLRYDHYDQDSKDTIa 369
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 952994189 479 ------------SWQFVGAYNINSKHLLRATYSRANRGSFMGNAYANfqnplGPNYYQFYVGDENLNLLTQDLIEVGYRG 546
Cdd:cd01347 370 ggttakksyshwSPSLGLVYKLTDGLSLYASYSQGFRAPSLGELYGG-----GSHGGTAAVGNPNLKPEKSKQYELGLKY 444
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 952994189 547 ILTNYLQVDFEAFRTKTTDFdALFPKVYEIDGGITYdqwYYQNIDMESEqlGATLNVAVQPLDNLIIKVFGTYQNTKLTH 626
Cdd:cd01347 445 DPGDGLTLSAALFRIDIKNE-IVSTPTNTGLGLVTV---YVNGGKARIR--GVELEASYDLTDGLGLTGSYTYTDTEVKR 518
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 952994189 627 VLKDIsefytinfitgqqsmtpyseldessfEDGNNDWTPGFYGGAMINYT-PVQKFNINASLYYYDKQTysRYYFAYPT 705
Cdd:cd01347 519 TDGAT--------------------------TGNRLPGIPKHTANLGLDYElPDEGLTAGGGVRYRGKQY--ADTANGNN 570
|
650 660 670
....*....|....*....|....*....|....*..
gi 952994189 706 HKTmeasLDPNVILNAKVAYRISNNASVYLSGQNILD 742
Cdd:cd01347 571 TVK----VPGYTLVDLSASYQFTKNLTLRLGVNNLFD 603
|
|
| Fiu |
COG4774 |
Outer membrane receptor for monomeric catechols [Inorganic ion transport and metabolism]; |
80-742 |
3.37e-24 |
|
Outer membrane receptor for monomeric catechols [Inorganic ion transport and metabolism];
Pssm-ID: 443806 [Multi-domain] Cd Length: 639 Bit Score: 108.04 E-value: 3.37e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 952994189 80 KKGESVFESPLSTTVITKEEIKLTGATTYEELFRLVPGMIVRQESNGNYD-IHIRGndnlppgnFSHFSEnmmtlVMVDG 158
Cdd:COG4774 1 KTDTPLLDTPQSVTVVTRELIEDQGATSLADALRNVPGVTFGAGEGGNGDsFSIRG--------FSASGD-----IYVDG 67
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 952994189 159 -RIVYNYinggtiweslPVAMSDIERIEIIRGASSALYGPNAVSGVINIITRTPdKDGAQVHGDVKVGNSDTYIGNFSLL 237
Cdd:COG4774 68 lRDPGQY----------RRDTFNLERVEVLKGPASVLYGRGSPGGVINLVTKRP-TDEPFTEVTLTYGSDGQRRATLDVN 136
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 952994189 238 NKISEDFGFKVSGAYD----FRDRFQDDFYEYA-SGTYVPAD--SLTSMFGNQLHASSPD----AELAKKAFNANAGLFY 306
Cdd:COG4774 137 GPLGDDLAYRLNGMYRdsdsYRDGVDNDRWGIApSLTWRLGDrtRLTLDYEYQDDDRTPDygvpAVANGRPVDVDRSTFY 216
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 952994189 307 --------------------EPSNDLSMSLNGGWQSSESQSMFFENLATpfgireSETGyvDYKASAYGFQAQVNYLTGR 366
Cdd:COG4774 217 gqpddysdsetdsatlrlehDFNDNWTLRNALRYSDYDRDYRNTYPTGG------NATG--TVTRSAYRRDQDNDTLSNQ 288
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 952994189 367 QNLhekmikpvieyDMNFLSANLEYDLVLndlgigeltvrpGFNYQLANYDDKTYVEKVDT-------------VGDLDR 433
Cdd:COG4774 289 TDL-----------TGKFDTGGVKHTLLA------------GVEYSREDSDNARYSGGGTAptvnlynpvygapVTGPTL 345
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 952994189 434 GLLNGEKSLETISGSMRIDYKPISELRLIAALRADKYNVP-------------DDIYMSWQFVGAYNINSKHLLRATYSR 500
Cdd:COG4774 346 GGADNDSRTDTTGLYLQDTISLTDRWSLLAGLRYDRFDTDytdrttgattssyDDSAFSPRAGLVYKPTPNLSLYASYST 425
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 952994189 501 ANRGSFMGNAYANFQNPLGPnyyqfYVGdenlnlltqDLIEVGYRG-ILTNYLQVDFEAFRTKTTD---FDALFPKVYEI 576
Cdd:COG4774 426 SFNPGGGAPSLSNAGQALDP-----EKS---------RQYEVGVKWdLLDGRLSLTAALFRIEKTNvrtTDPANPGVYVQ 491
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 952994189 577 DGGITYDqwyyqnidmeseqlGATLNVAVQPLDNLiiKVFG--TYQNTKLTHvlkdisefytinfitgqqsmtpyselDE 654
Cdd:COG4774 492 TGEQRSR--------------GVELEATGELTPGW--SVLAgyTYLDAEITK--------------------------SA 529
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 952994189 655 SSFEDGNN-DWTPGFYGGAMINYT-PVQKFNINASLYYYDKQtysryyFAYPTHKTmeaSLDPNVILNAKVAYRISNNAS 732
Cdd:COG4774 530 NAANVGNRlPNVPRHSASLWTTYDlPLPGLTLGGGVRYVGSR------YADAANTV---KLPSYTRFDAGASYRLNKNLT 600
|
730
....*....|
gi 952994189 733 VYLSGQNILD 742
Cdd:COG4774 601 LRLNVNNLTD 610
|
|
| Plug |
pfam07715 |
TonB-dependent Receptor Plug Domain; The Plug domain has been shown to be an independently ... |
84-203 |
5.04e-23 |
|
TonB-dependent Receptor Plug Domain; The Plug domain has been shown to be an independently folding subunit of the TonB-dependent receptors. It acts as the channel gate, blocking the pore until the channel is bound by ligand. At this point it under goes conformational changes opens the channel.
Pssm-ID: 462243 [Multi-domain] Cd Length: 107 Bit Score: 94.26 E-value: 5.04e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 952994189 84 SVFESPLSTTVITKEEIKLTGATTYEELFRLVPGMIVRQESNGNYD-IHIRGndnlppgnfshFSENMmTLVMVDGRIVY 162
Cdd:pfam07715 1 DLRDTPGSVSVVTAEDIEDQGATNLADALRGVPGVSVSSGGGGGGSsISIRG-----------FGSNR-VLVLVDGVPLN 68
|
90 100 110 120
....*....|....*....|....*....|....*....|.
gi 952994189 163 NYINGGTIWESLPvaMSDIERIEIIRGASSALYGPNAVSGV 203
Cdd:pfam07715 69 SGGGGSVDLNSID--PEDIERVEVLKGPASALYGSGAIGGV 107
|
|
| TonB-siderophor |
TIGR01783 |
TonB-dependent siderophore receptor; This subfamily model encompasses a wide variety of ... |
87-537 |
8.81e-21 |
|
TonB-dependent siderophore receptor; This subfamily model encompasses a wide variety of TonB-dependent outer membrane siderophore receptors. It has no overlap with TonB receptors known to transport other substances, but is likely incomplete due to lack of characterizations. It is likely that genuine siderophore receptors will be identified which score below the noise cutoff to this model at which point the model should be updated. [Transport and binding proteins, Cations and iron carrying compounds, Transport and binding proteins, Porins]
Pssm-ID: 273805 [Multi-domain] Cd Length: 651 Bit Score: 97.48 E-value: 8.81e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 952994189 87 ESPLSTTVITKEEIKLTGATTYEELFRLVPGmIVRQESNGNYD---IHIRGndnlppgnfshFSENMMTL-VMVDGRIVY 162
Cdd:TIGR01783 1 DIPQSVSVITRQELEDQQAGSLSEALQRVPG-VVVGGSGGTTQfgnITIRG-----------FGLEVDIDnVYLDGVPLL 68
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 952994189 163 NYINggtiweSLPVAMSDIERIEIIRGASSALYGPNAVSGVINIITRTPDKDGAQvHGDVKVGNSDTYIGNFSLLNKISE 242
Cdd:TIGR01783 69 SRGN------LAIVDPAMVERVEVLRGPASLLYGGSAPGGVINIVTKRPQDEPKG-SVTFGAGTRSGYRTAFDLGGPLGA 141
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 952994189 243 DFGFKVSGAYDFRDRfqDDFYEYAS--------GTYVPADSLT------------SMFGNQLHASSPDAELAKKAFNANA 302
Cdd:TIGR01783 142 DGTFRGRLNGARQDG--DSFYDGAGeetrlgatATDWQLDDRTllrlgayyqkerDRGGYGGLPASGGTSGRDLSSDRYL 219
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 952994189 303 GlfyEPSNDLSMSLNGGWQSSESQSMFFENLATPFGIRESETGYVDYKASAYGFQAQVNYLTGRQNLHEKMIKPVI---E 379
Cdd:TIGR01783 220 G---TSSNRNYDDREYLSYGLSLEYQFNDVWTGKQNLRYSYFDTDSNQVQASGYSSDGGLFGRSLTVVNVKQDRVQidaG 296
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 952994189 380 YDMNFLSANLEYDLVlndLGIGELTVRPGFNYQLANYDDKTYVEKVDTVGD-------LDRGLLNGEKSLETISGSMRID 452
Cdd:TIGR01783 297 LDGEFETGPIEHDLL---LGVSYGQRTTNRFNNTGYPSDNIYSLTATSSARtdigdspKDRALSSTTKALNGVALQRILL 373
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 952994189 453 ykpISELRLIAALRADKYNV------------PDDIYMSWQFVGAYNINSKHLLRATYSRANRGSFMGNAYANFQN-PLG 519
Cdd:TIGR01783 374 ---ADKWTLTLGGRYDSVDVksnngvagstgkRDDSQFTPSLGVAYKPTDDWSLYASYAESFKPGGYYPKGAGNSGdILE 450
|
490 500
....*....|....*....|.
gi 952994189 520 P---NYYQFYVGDENLNLLTQ 537
Cdd:TIGR01783 451 PekgKNYELGVRYDLGDSLLA 471
|
|
| FecA |
COG4772 |
Outer membrane receptor for Fe3+-dicitrate [Inorganic ion transport and metabolism]; |
74-742 |
1.07e-20 |
|
Outer membrane receptor for Fe3+-dicitrate [Inorganic ion transport and metabolism];
Pssm-ID: 443804 [Multi-domain] Cd Length: 681 Bit Score: 97.31 E-value: 1.07e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 952994189 74 EVSSASKKGESVFESPLSTTVITKEEIKLTGATTYEELFRLVPGMIVRQESNGNYD--IHIRGNDnlppgnfSHFSENmm 151
Cdd:COG4772 27 VVTGSRAAEARLKDVPGSVSVVDREELENQAATSLREVLRRVPGVNVQEEDGFGLRpnIGIRGLG-------PRRSRG-- 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 952994189 152 TLVMVDGRIVY--NYINGGTiweSLPVAMSDIERIEIIRGASSALYGPNAVSGVINIITRT-PDKDGAQVhgDVKVGNSD 228
Cdd:COG4772 98 ITLLEDGIPIApaPYGDPAA---YYFPDLERMERIEVLRGAAALRYGPQTVGGAINFVTRTiPTAFGGEL--RVTGGSFG 172
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 952994189 229 TYIGNFSLLNKIsEDFGFKVSGAYDFRDRFQDDfyeyaSGTyvpadsltsmfgnqlhasspdaelakKAFNANAGLFYEP 308
Cdd:COG4772 173 YRRTHASVGGTV-GNFGYLVEYSRKRGDGFRDN-----SGF--------------------------DINDFNAKLGYRL 220
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 952994189 309 SNDLSMSLNGGWQSSESQsmffenlaTPFGIRESetgyvDYKASAYGFQAQVNYLTGRQNL----HEKMIKPVIE----- 379
Cdd:COG4772 221 SDRQELTLKFQYYDEDAN--------TPGGLTDA-----QFDADPRQSYRPADQFDTRRTQlslrYEHQLSDNTTlttta 287
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 952994189 380 ----------YDMNFLSANLEYDLVLN------------------DLGIGELTVRPGFNYQLANYDDKTYvekVDTVGDL 431
Cdd:COG4772 288 yyndfsrnwyIRQNTADPNTPGLGLRGnprgyrsygieprlthrfELGGVPHTLEVGLRYHREEEDRKQY---VNTYGQG 364
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 952994189 432 DRGLLNGEKSLET-------ISGSMRIDykpiSELRLIAALRAD--KYNVpDDIYMSWQFVGAYNINSKH--LLR--ATY 498
Cdd:COG4772 365 RSGAGLRRDRRFSadalaayAQNRFELT----GRLTLTPGLRYEhiRRDR-TDRYSTRTGGDDSGSNSYSefLPGlgLLY 439
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 952994189 499 SRANRGSFMGNAYANFQnPlgPNYYQ-FYVGDENLNLLTQ--DLIEVGYRGILTNYLQVDFEAFRtktTDFDALFPKVYE 575
Cdd:COG4772 440 QLTDNLQLYANVSRGFE-P--PTFGDlAYGNGGNPDLKPEksWNYELGTRGRIGNGLSAEVALFY---IDYDNELGSCSA 513
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 952994189 576 IDGGITydqwYYQNIDmESEQLG--ATLNVAVQPLDNLIIKVFGTYQNTKlTHVLKDISEFYTINFItgqqsmtPYseld 653
Cdd:COG4772 514 AGGDRS----TFTNAG-ETRHQGleLALDYDLLKGGGLGLPLFAAYTYTD-AEFTSDFGPVFAGNRL-------PY---- 576
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 952994189 654 essfedgnndwTPGFYGGAMINYTPvQKFNINASLYYYDKQtYSRYyfAYPTHKTMEASLDPNVILNAKVAYRISNNASV 733
Cdd:COG4772 577 -----------VPRHQLTAGLGYEH-GGWTANLNGRYVSEQ-FTDA--ANTVADGSFGKIPSYTVLDLSASYDFGKNLSL 641
|
....*....
gi 952994189 734 YLSGQNILD 742
Cdd:COG4772 642 FAGVNNLFD 650
|
|
| PRK13483 |
PRK13483 |
ligand-gated channel protein; |
63-326 |
2.33e-19 |
|
ligand-gated channel protein;
Pssm-ID: 184080 [Multi-domain] Cd Length: 660 Bit Score: 92.92 E-value: 2.33e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 952994189 63 TDELLDLALNREVSSASKKGESVFESPLSTTVITKEEIK------LTGAttyeelFRLVPGMIVRQESNGNyDIHIRGNd 136
Cdd:PRK13483 25 AQAAPDKTMETVVVTASGYEQQIRDAPASISVITREDLEnrfyrdLTDA------LLDVPGVVVTGGGDRT-DISLRGM- 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 952994189 137 nlpPGNFshfsenmmTLVMVDGR------IVYNYINGGTIWESLPvAMSDIERIEIIRGASSALYGPNAVSGVINIITRt 210
Cdd:PRK13483 97 ---GSQY--------TLILVDGKrqssreTRPNSDGPGVEQAWTP-PLAAIERIEVIRGPMSSLYGSDAIGGVINIITR- 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 952994189 211 pdKDGAQVHGDVKVG-----NSDT---YIGNFSLLNKISED-FGFKVSGAYDFRDrfQDDFYEYASGTyvPADSLTSMFG 281
Cdd:PRK13483 164 --KVPNEWQGEVRLDttlqeNSDSgnvYQANFFVNGPLIKDlLGLQLYGQYTQRE--EDDIEGGYRDK--DARSLTAKLA 237
|
250 260 270 280
....*....|....*....|....*....|....*....|....*....
gi 952994189 282 ---NQLHASSPDAELAKKAFNANAGLFYEP-SNDLSMSLNGGWQSSESQ 326
Cdd:PRK13483 238 ltpNEDHDIMLEVGTSNQERDSTVGKTVAPlAPGESCGRRGCPESSTTE 286
|
|
| TonB-B12 |
TIGR01779 |
TonB-dependent vitamin B12 receptor; This model represents the TonB-dependent outer membrane ... |
70-742 |
1.05e-18 |
|
TonB-dependent vitamin B12 receptor; This model represents the TonB-dependent outer membrane receptor found in gamma proteobacteria responsible for translocating the cobalt-containing vitamin B12 (cobalamin). [Transport and binding proteins, Other, Transport and binding proteins, Porins]
Pssm-ID: 273802 [Multi-domain] Cd Length: 614 Bit Score: 90.69 E-value: 1.05e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 952994189 70 ALNREVSSASKKGESVFESPLSTTVITKEEIKLTGATTYEELFRLVPGMIVRQesNG----NYDIHIRGNdnlppgNFSH 145
Cdd:TIGR01779 27 PLDTVVVTANRFAQTASQTLAPVTIITRQDIERTQAKSLPELLRRLPGVSIAQ--NGgrgqNTSLFLRGT------ESDH 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 952994189 146 fsenmmTLVMVDGRIVYNYINGGTIWESLPVAMsdIERIEIIRGASSALYGPNAVSGVINIITRTPDkDGAQVHGDVKVG 225
Cdd:TIGR01779 99 ------VLVLIDGIRFGSAAAGAADFQQLPVEL--VERIEYVRGPRSSLYGSEAIGGVINIITRRRS-GGQGTTLSAGLG 169
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 952994189 226 NSDTYIGNFSLLNKISEDFGFKVSGAYDFRDRFqdDFYEYASGTYVP------ADSLTSMFGNQLHAS-SPDAElAKKAF 298
Cdd:TIGR01779 170 SLDYQEYSIASGVAIGENGWYSVALGTESTKGI--NVRPGGPGVYDPdrdgfrSDSLLLGGGHRFDESwSLFVN-ALRYE 246
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 952994189 299 NANAGLFYEPSNDLSMSLNGGWQSSESQSMFFenlaTPFGIRESETGYVDYKASAYGFQaQVNYLTGRQNLHEKMIKpvi 378
Cdd:TIGR01779 247 NRNDYDNYSFGTRLYKEAEKGDQSFTGGRQRQ----SERDVSELTLSTGKSKDWDYAYS-KGRYSSTSDTREQRNIQ--- 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 952994189 379 eydmnflsanLEYDLVLNDLGIGELtvrpGFNYQLANYDDKTYVEKVDTvgdLDRGLLN------GEKSLEtisgsmrid 452
Cdd:TIGR01779 319 ----------WQNDLLVGDGWVLAG----GVDWQKDSIISSTADKEDDR---SNTAAFAqvlqqwGQQLLE--------- 372
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 952994189 453 ykpiselrliAALRAD---KYNVPD--DIYMSWQFVGAYNinskhlLRATYsranrgsfmGNAYAnfqnplGPNYYQFY- 526
Cdd:TIGR01779 373 ----------ASLRRDdnqQFGSHTtgSIAWGYQFIEELR------FTASY---------GTAFK------APNLNQLYy 421
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 952994189 527 --VGDENLNLLTQDLIEVGYRGiLTNYLQVDFEAFRTKttdfdalfpkvyeIDGGITYDQ--WYYQNIDMESEQLG--AT 600
Cdd:TIGR01779 422 psYGNPNLQPETSKSAELGFYG-LFSGGKWSISGYRTK-------------INDLIDYDShpKGYPNNIGEARIKGveAT 487
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 952994189 601 LNVAVQPLDNLIIKVFGTYQNTKLTHVLKDISEfytinfitgqqSMTPYseldessfedgNNDWTpgfyggaminytpVQ 680
Cdd:TIGR01779 488 AEFATGGWTHQLSVDLLDAQNVNTGNTLPRRAR-----------QMYKW-----------NADRA-------------FE 532
|
650 660 670 680 690 700
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 952994189 681 KFNINASLYYYDKqtysRYYFAYPTHKTMEASLDPNVILNAKVAYRISNNASVYLSGQNILD 742
Cdd:TIGR01779 533 QFDWGASYQYVGK----RYDDDYNTYPTQNVRLGGYSLLDLRVSYYVTDSWTVQGRIANLFD 590
|
|
| TonB-hemin |
TIGR01785 |
TonB-dependent heme/hemoglobin receptor family protein; This model represents the ... |
75-591 |
1.53e-18 |
|
TonB-dependent heme/hemoglobin receptor family protein; This model represents the TonB-dependent outer membrane heme/hemoglobin receptor/transporter found in bacteria which live in contact with animals (which contain hemoglobin or other heme-bearing globins) or legumes (which contain leghemoglobin). Some species having hits to this model such as Nostoc, Caulobacter and Chlorobium do not have an obvious source of hemoglobin-like proteins in their biological niche and so the possibility exists that they act on some other substance. [Transport and binding proteins, Cations and iron carrying compounds, Transport and binding proteins, Porins]
Pssm-ID: 273807 [Multi-domain] Cd Length: 665 Bit Score: 90.14 E-value: 1.53e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 952994189 75 VSSASKKGESVFESPLSTTVITKEEIKLTGATTYEELFRLVPG--MIVRQESNGNyDIHIRGndnlppgnfshFSENMMt 152
Cdd:TIGR01785 5 TVTATRTRQVLSEAPASVSVISGEQIESKQANNLADALNTVPGvdVTGGGRPPGQ-SINIRG-----------LQDNRV- 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 952994189 153 LVMVDGrIVYNYINGGTIWESLPVAMSDIERIEIIRGASSALYGPNAVSGVINIITRTPD---KDGAQVHGDVKVGNSdt 229
Cdd:TIGR01785 72 LVVVDG-ARQNYQRGGAHNGSLFVDPELLKRIEIVKGPSSSLYGSGALGGVVAFRTKDAAdllRPGQLFGGLAKLSYG-- 148
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 952994189 230 yignfsllnKISEDFGFKVSGAYdfrdRFQDDFYEYASGTYVPADSLTSmfGNQLHASSpdaelakKAFNANAGLF---Y 306
Cdd:TIGR01785 149 ---------SNNNSFGGSVAVAG----RLDDNLDALVAATYRDGGNYRN--GNKEEATN-------SAYVQKNLLAklgW 206
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 952994189 307 EPSNDLSMSLNGGWQssESQSMFFENLATPFGIRESETGYV-DYKASAYGFQAQVNYLTGRQNLHEKMIKP--VIEYDMN 383
Cdd:TIGR01785 207 QLDDAQRLEFSYFTT--EGSLDEAQNSGPGTEYVLGSSSTLlASSTRDRSATLTYNWTPEDNPWLDATASLyyNRTENDN 284
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 952994189 384 FLSAN---LEYDLVLNDLGIgelTVRPGFNYQLANYDDKTYveKVDTVGDLDRGLLNGEKSLETI-----------SGSM 449
Cdd:TIGR01785 285 DRSARgvgREEGYQYTTYGA---TLQNTSRFDVASWSTLTY--GVDWMKDKRRTESFDPNSVTTIvpnppsakeyfFGLF 359
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 952994189 450 RIDYKPI--SELRLIAALRADKY-NVPDD-IYMSWQFVGAYNINSKHLLR----------ATYSRANRGSFMGNAYANFQ 515
Cdd:TIGR01785 360 LQDNIPLldDRLTLSAGLRYDHYkLSPKTtADTEAVDRSYSRWSPSLGLSykpvdwltlyASYSQGFRAPSIDELYGTGD 439
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 952994189 516 NPLGPNYYQFYvGDENLNLLTQDLIEVGYR----GILTNYLQVDFEA--FRTKTTDFDALFPKVY--EIDGGITYDQwyY 587
Cdd:TIGR01785 440 HPGTPGGYTFA-PNPNLKPETSKTWELGANlsfdNLLLDNDQLQFKVayFYNDVKDFIDLTIGVTdnVTAGMNNITQ--Y 516
|
....
gi 952994189 588 QNID 591
Cdd:TIGR01785 517 VNID 520
|
|
| PRK10064 |
PRK10064 |
catecholate siderophore receptor CirA; Provisional |
75-257 |
1.70e-17 |
|
catecholate siderophore receptor CirA; Provisional
Pssm-ID: 236646 [Multi-domain] Cd Length: 663 Bit Score: 86.86 E-value: 1.70e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 952994189 75 VSSASKKGESVFESPLSTTVITKEEIKLTGATTYEELFRLVPGMIVRQESNGNYDIHIRGNDNlppgnfshfsenMMTLV 154
Cdd:PRK10064 34 VVTASAVEQNLKDAPASISVITQEDLQRKPVQNLKDVLKEVPGVQLTNEGDNRKGVSIRGLDS------------SYTLI 101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 952994189 155 MVDGR------IVYNYINGGTIWesLPVamSDIERIEIIRGASSALYGPNAVSGVINIITRtpdKDGAQVHGDVKVGNS- 227
Cdd:PRK10064 102 LIDGKrvnsrnAVFRHNDFDLNW--IPV--DAIERIEVVRGPMSSLYGSDALGGVVNIITK---KIGQKWHGTVTVDTTi 174
|
170 180 190
....*....|....*....|....*....|....*...
gi 952994189 228 -------DTYIGNFSLLNKISED-FGFKVSGAYDFRDR 257
Cdd:PRK10064 175 qehrdrgDTYNGQFFTSGPLIDGvLGMKAYGSLAKREK 212
|
|
| PRK13513 |
PRK13513 |
ligand-gated channel protein; |
75-264 |
4.80e-16 |
|
ligand-gated channel protein;
Pssm-ID: 184104 [Multi-domain] Cd Length: 659 Bit Score: 82.12 E-value: 4.80e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 952994189 75 VSSASKKGESVFESPLSTTVITKEEIKLTGATTYEELFRLVPGMIVrQESNGNYDIHIRGNDNlppgnfshfsenMMTLV 154
Cdd:PRK13513 39 VVTASGFQQRIQDAPASISVVTREQLENKAYRDVTDALKDVPGVVV-TGGGSTSDISIRGMAA------------KYTLI 105
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 952994189 155 MVDGRIVY------NYINGGTIWESLPvAMSDIERIEIIRGASSALYGPNAVSGVINIITRTPDKD-GAQVHGDVKVGNS 227
Cdd:PRK13513 106 LVDGKRVDtrstrpNSDGSGIEQGWLP-PLAAIERIEVVRGPMSSLYGSDAMGGVINIITRKVQKEwHGSLRADATLQED 184
|
170 180 190 200
....*....|....*....|....*....|....*....|....
gi 952994189 228 ----DTYIGNFSLLNKISED-FGFKVSGAYDFR--DRFQDDFYE 264
Cdd:PRK13513 185 sksgDIFQTNAYASGPLIDGlLGLKVSGLLSHRseDKIIDGYNE 228
|
|
| PRK13484 |
PRK13484 |
IreA family TonB-dependent siderophore receptor; |
55-293 |
8.06e-16 |
|
IreA family TonB-dependent siderophore receptor;
Pssm-ID: 139605 [Multi-domain] Cd Length: 682 Bit Score: 81.59 E-value: 8.06e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 952994189 55 MAEAIGISTDELLDLALNREVSSASKKGESVFESPLSTTVITKEEIKLTGATTYEELFRLVPGMIVRQESNgNYDIHIRG 134
Cdd:PRK13484 14 MCSAVISSGYASSDKKEDTLVVTASGFTQQLRNAPASVSVITSEQLQKKPVSDLVDAVKDVEGISITGGNE-KPDISIRG 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 952994189 135 ndnlPPGNFshfsenmmTLVMVDGRIVY---NYINGGTIWES--LPVAMSdIERIEIIRGASSALYGPNAVSGVINIITR 209
Cdd:PRK13484 93 ----LSGDY--------TLILVDGRRQSgreSRPNGSGGFEAgfIPPVEA-IERIEVIRGPMSSLYGSDAIGGVINIITK 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 952994189 210 TPDK---DGA-------QVHGDvkVGNSDTyiGNFSLLNKISED-FGFKVSGAYDFRdrfQDDFYEYASG---------- 268
Cdd:PRK13484 160 PVNNqtwDGVlglggiiQEHGK--FGNSTT--NDFYLSGPLIKDkLGLQLYGGMNYR---KEDSISQGTPakdnknitat 232
|
250 260 270
....*....|....*....|....*....|
gi 952994189 269 -TYVPADSLTSMF----GNQLHASSPDAEL 293
Cdd:PRK13484 233 lQFTPTESQKFVFeygkNNQVHTLTPGESL 262
|
|
| btuB |
PRK10641 |
TonB-dependent vitamin B12 receptor BtuB; |
86-281 |
7.96e-14 |
|
TonB-dependent vitamin B12 receptor BtuB;
Pssm-ID: 236730 [Multi-domain] Cd Length: 614 Bit Score: 75.03 E-value: 7.96e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 952994189 86 FESPLS-----TTVITKEEIKLTGATTYEELFRLVPGMIVRQesNG----NYDIHIRGNdnlppgNFSHfsenmmTLVMV 156
Cdd:PRK10641 35 FQQPVStvlapTTVVTRDDIDRWQSKSVNDVLRRLPGVDIAQ--NGglgqLSSLFIRGT------NSSH------VLVLI 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 952994189 157 DG-RIVYNYINGGTIWESLPVAMsdIERIEIIRGASSALYGPNAVSGVINIITRTpDKDGAQVHGDVKVGNSDTYIGnfS 235
Cdd:PRK10641 101 DGvRLNQAGISGSADLSQIPISL--VQRIEYIRGPRSAVYGSDAIGGVVNIITTR-DKPGTTLSAGWGSNGYQNYDG--S 175
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 952994189 236 LLNKISEDFGFKVSGAydfrdrfqddfYEYASGTYVPADSLTSMFG 281
Cdd:PRK10641 176 TQQQLGDNTRVTLAGD-----------YTYTKGFDVVAYGNTGTQA 210
|
|
| PRK13524 |
PRK13524 |
FepA family TonB-dependent siderophore receptor; |
90-253 |
2.79e-12 |
|
FepA family TonB-dependent siderophore receptor;
Pssm-ID: 237410 [Multi-domain] Cd Length: 744 Bit Score: 70.44 E-value: 2.79e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 952994189 90 LSTTVITKEEI-KLTGATTYEELFRLVPGMIVRQESNG-----NYDIHIRGndnLPPGNfshfsenmmTLVMVDGRIV-- 161
Cdd:PRK13524 53 PGVSTITAEDIrKRPPANDVSEIIRTMPGVNLTGNSTSgqrgnNRQIDIRG---MGPEN---------TLILIDGKPVss 120
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 952994189 162 YNYIN----------GGTIWesLPVAMsdIERIEIIRGASSALYGPNAVSGVINIITRTPDKdgaQVHGDVKV-GNS--- 227
Cdd:PRK13524 121 RNSVRygwrgerdtrGDTNW--VPPEM--IERIEVLRGPAAARYGNGAAGGVVNIITKKPTG---EWHGSWNTyFNApeh 193
|
170 180 190
....*....|....*....|....*....|
gi 952994189 228 ----DTYIGNFSLLNKISEDFGFKVSGAYD 253
Cdd:PRK13524 194 kaegATKRTNFSLSGPLGDELSFRLYGNLN 223
|
|
| PRK13528 |
PRK13528 |
outer membrane receptor FepA; Provisional |
83-253 |
1.35e-10 |
|
outer membrane receptor FepA; Provisional
Pssm-ID: 237413 [Multi-domain] Cd Length: 727 Bit Score: 64.78 E-value: 1.35e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 952994189 83 ESVFESPLSTTVITKEEIKLTGATT-YEELFRLVPGM-IVRQESNG----NYDIHIRGndnLPPGNfshfsenmmTLVMV 156
Cdd:PRK13528 44 EQELKQQPGVSIITAEDIKKRPPVNdLSDIIRKMPGVnLTGNSASGtrgnNRQIDIRG---MGPEN---------TLILI 111
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 952994189 157 DGRIV-------YNY-----INGGTIWeslpVAMSDIERIEIIRGASSALYGPNAVSGVINIITRTPDKDgaqVHGDVKV 224
Cdd:PRK13528 112 DGVPVtsrnsvrYSWrgerdTRGDTNW----VPPEMVERIEVIRGPAAARYGSGAAGGVVNIITKRPTND---WHGSLSL 184
|
170 180 190
....*....|....*....|....*....|....*...
gi 952994189 225 -GNS-------DTYIGNFSLLNKISED-FGFKVSGAYD 253
Cdd:PRK13528 185 yTNQpesskegATRRANFSLSGPLAGDaLTMRLYGNLN 222
|
|
| PRK13486 |
PRK13486 |
TonB-dependent receptor; |
75-238 |
1.58e-09 |
|
TonB-dependent receptor;
Pssm-ID: 139606 [Multi-domain] Cd Length: 696 Bit Score: 61.19 E-value: 1.58e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 952994189 75 VSSASKKGESVFESPLSTTVITKEEIKLTGATTYEELFRLVPGMIVRQES--NGNYDIHIRGNdnlpPGNFshfsenmmT 152
Cdd:PRK13486 29 IVSASGYEKKLTNAAASVSVISQEELQSSQYHDLAEALRSVEGVDVESGTgkTGGLEISIRGM----PASY--------T 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 952994189 153 LVMVDGrivynYINGGT----------IWESLPVAMSDIERIEIIRGASSALYGPNAVSGVINIIT-RTPDKDGAQVHGD 221
Cdd:PRK13486 97 LILIDG-----VRQGGSsdvtpngfsaMNTGFMPPLAAIERIEVIRGPMSTLYGSDAMGGVVNIITrKNADKWLSSVNAG 171
|
170
....*....|....*..
gi 952994189 222 VKVGNSDTYiGNFSLLN 238
Cdd:PRK13486 172 LNLQESNKW-GNSSQFN 187
|
|
| TonB_dep_Rec |
pfam00593 |
TonB dependent receptor; This model now only covers the conserved part of the barrel structure. |
346-742 |
1.37e-08 |
|
TonB dependent receptor; This model now only covers the conserved part of the barrel structure.
Pssm-ID: 395474 [Multi-domain] Cd Length: 475 Bit Score: 57.86 E-value: 1.37e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 952994189 346 YVDYKASAYGFQAQVNYLTGRQNLHEKMIKPVIEYDMNFLSANLEYDlvlNDLGIGELTVRPGFNYQLANYDDKTYVEKV 425
Cdd:pfam00593 84 GLRYSSLDGDYTSNSSGLSGAGDYLSDDRLYGLYGLDGDLELSLDLS---HDLLLGVELRTAGLDYRRLDDDAYDPYDPA 160
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 952994189 426 DTVGDLDRGLlngekSLETISGSMRIDYKPISELRLIAALRADKYNV-------------PDDIYMSWQFVGAYNINSKH 492
Cdd:pfam00593 161 NPSSSSYSDT-----TTDSYGLYLQDNIKLTDRLTLTLGLRYDHYSTdgddgngggdnfsRSYSAFSPRLGLVYKPTDNL 235
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 952994189 493 LLRATYSRANRgsfMGNAYANFQNPLGPNYYQFYVGDENLNLLTQDLIEVGYRgILTNYLQVDFEAFRTKTTDFDALFPk 572
Cdd:pfam00593 236 SLYASYSRGFR---APSLGELYGSGSGGGGGAVAGGNPDLKPETSDNYELGLK-YDDGRLSLSLALFYIDIKNLITSDP- 310
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 952994189 573 vyeIDGGITYDQWYYQNIDmESEQLGATLNVAVQPLDNLIIKVFGTYQNTKlthvlKDISEFYTINFITGqqsmtpysel 652
Cdd:pfam00593 311 ---DGPGLGGTVYTYTNVG-KARIRGVELELSGRLWGLGLSGGGYTYTDAD-----DDADADDTGNPLPN---------- 371
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 952994189 653 dessfedgnndwTPGFYGGAMINYTPVQ-KFNINASLYYYDKQTySRYYFAYPTHKTmeaslDPNVILNAKVAYRISNNA 731
Cdd:pfam00593 372 ------------VPRHTANLGLTYDFPLgGWGARLGARYVGSGE-RRYGDAANTFKT-----PGYTLVDLSAGYRLNKNL 433
|
410
....*....|.
gi 952994189 732 SVYLSGQNILD 742
Cdd:pfam00593 434 TLRLGVNNLFD 444
|
|
| OMP_RagA_SusC |
TIGR04056 |
TonB-linked outer membrane protein, SusC/RagA family; This model describes a distinctive clade ... |
115-519 |
8.89e-07 |
|
TonB-linked outer membrane protein, SusC/RagA family; This model describes a distinctive clade among the TonB-linked outer membrane proteins (OMP). Members of this family are restricted to the Bacteriodetes lineage (except for Gemmatimonas aurantiaca T-27 from the novel phylum Gemmatimonadetes) and occur in high copy numbers, with over 100 members from Bacteroides thetaiotaomicron VPI-5482 alone. Published descriptions of members of this family are available for RagA from Porphyromonas gingivalis, SusC from Bacteroides thetaiotaomicron, and OmpW from Bacteroides caccae. Members form pairs with members of the SusD/RagB family (pfam07980). Transporter complexes including these outer membrane proteins are likely to import large degradation products of proteins (e.g. RagA) or carbohydrates (e.g. SusC) as nutrients, rather than siderophores. [Transport and binding proteins, Unknown substrate]
Pssm-ID: 274948 [Multi-domain] Cd Length: 981 Bit Score: 52.59 E-value: 8.89e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 952994189 115 VPGMIVRQES---NGNYDIHIRGNdnlppgnfSHFSENMMTLVMVDGRIVYNYINGgtiweslpVAMSDIERIEIIRGAS 191
Cdd:TIGR04056 122 VAGVIITQSSgepGGDAEIWIRGI--------SSFGGNNSPLYVIDGVPRDNGLSD--------LNPEDIESISVLKDAS 185
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 952994189 192 S-ALYGPNAVSGVInIITrTpdKDGAQvhGDVKVgnsdTYIGNFSLLNKISEDfgfKVSGAYDFRdRFQDDFYEYASGTY 270
Cdd:TIGR04056 186 AtAIYGSRGANGVI-LIT-T--KRGKE--GKPKI----SYNAEFGFSTPTRLP---EMLNAYEYA-ELYNEALLNRGSSP 251
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 952994189 271 VP---ADSLTSMFGNQLHASSPDAELAKKAFNANAglfyePSNDLSMSLNGGwqssesqsmfFENLATPFGireseTGYV 347
Cdd:TIGR04056 252 PDiytDEEIEAYRNGLDPDLYPNTDWQDEIFKRTA-----FNQRHNLSVSGG----------TEKARYYVS-----LGYY 311
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 952994189 348 DYKA-------SAYGFQAQVNYltgrqNLHEKMIkpvieydmnfLSANLEYDLVLNDLGIGE--------LTVRPGFNYQ 412
Cdd:TIGR04056 312 NEEGilknsdyKRYNFRANIDA-----KLTKTLK----------LSLNVSGSLSKYNNPGGStsniwgalMLFPRGTPYS 376
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 952994189 413 LANYDDKTYVEKVDTVGDLDR---GLLNGEKSLE---TISGSMRIDYKPISELRLIAALRADKYNVPDDIYMSWQFVGAY 486
Cdd:TIGR04056 377 TPPVYSDGYYPAYNSGNTSLQnpyALLNRGYNENernRLNGNASLEQKITKGLKLKGTFSYDYSNYKNKKYYKNPYYYNA 456
|
410 420 430
....*....|....*....|....*....|...
gi 952994189 487 NINSKhLLRATYSRANRGSFMGNAYANFQNPLG 519
Cdd:TIGR04056 457 TGGAN-NGYYSESNSRSRNYYLEATLNYNRTFG 488
|
|
| PRK14050 |
PRK14050 |
TonB-dependent siderophore receptor; |
76-211 |
4.34e-06 |
|
TonB-dependent siderophore receptor;
Pssm-ID: 237595 [Multi-domain] Cd Length: 728 Bit Score: 50.18 E-value: 4.34e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 952994189 76 SSASKKGESVFESPLSTTVITKEEIKLTGATT-YEELFRLVPGMIVRQESN-GNYD-IHIRGNDNLPPGNFshfsenmmt 152
Cdd:PRK14050 67 ATGSKTDTPITEIPQSVSVVGRQEMDDRGVTNkVDEALRYTPGVLSQPFGTdGDTDwFYIRGFDATQTGVF--------- 137
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*....
gi 952994189 153 lvmVDGRIVYNYINGGTIWESLPvamsdIERIEIIRGASSALYGPNAVSGVINIITRTP 211
Cdd:PRK14050 138 ---LDGLNLFSYGFGGFQIDPFM-----LERVEVLKGPASVLYGGSNPGGIVNMVSKRP 188
|
|
| PRK14049 |
PRK14049 |
ferrioxamine B receptor precursor protein; Provisional |
181-243 |
8.67e-04 |
|
ferrioxamine B receptor precursor protein; Provisional
Pssm-ID: 172541 [Multi-domain] Cd Length: 726 Bit Score: 42.97 E-value: 8.67e-04
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 952994189 181 IERIEIIRGASSALYGPNAVSGVINIITRTPdKDGAQVHGDVKVGNSDTYIGNFSLLNKISED 243
Cdd:PRK14049 157 LEGVSILRGPSSALYGASGAGGLFNLITKRP-TEEPLREVQVQYGTNNRYQGQFDFSGPVNET 218
|
|
| SusC_RagA_signa |
TIGR04057 |
TonB-dependent outer membrane receptor, SusC/RagA subfamily, signature region; This model ... |
180-209 |
5.20e-03 |
|
TonB-dependent outer membrane receptor, SusC/RagA subfamily, signature region; This model describes a 31-residue signature region of the SusC/RagA family of outer membrane proteins from the Bacteriodetes. While many TonB-dependent outer membrane receptors are associated with siderophore import, this family seems to include generalized nutrient receptors that may convey fairly large oligomers of protein or carbohydrate. This family occurs in high copy numbers in the most abundant species of the human gut microbiome.
Pssm-ID: 274949 [Multi-domain] Cd Length: 31 Bit Score: 35.25 E-value: 5.20e-03
10 20 30
....*....|....*....|....*....|.
gi 952994189 180 DIERIEIIRGASS-ALYGPNAVSGVINIITR 209
Cdd:TIGR04057 1 DIESISVLKDASAaAIYGSRGANGVILITTK 31
|
|
| |
