|
Name |
Accession |
Description |
Interval |
E-value |
| CirA |
COG1629 |
Outer membrane receptor protein, Fe transport [Inorganic ion transport and metabolism]; |
10-643 |
7.38e-52 |
|
Outer membrane receptor protein, Fe transport [Inorganic ion transport and metabolism];
Pssm-ID: 441236 [Multi-domain] Cd Length: 644 Bit Score: 189.65 E-value: 7.38e-52
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 947383669 10 VSAIVVEAPRLPSLAGQEAFSTATYDARALSGQ--TRLDDVLKTTPGVSlFRRTGSDAANPTIQGLSlravapSGAGRAL 87
Cdd:COG1629 1 LEEVVVTATRTDESLQDVPGSVSVISREQLEDQpaTDLGDLLRRVPGVS-VTSAGGGAGQISIRGFG------GGGNRVL 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 947383669 88 VTLDGAPQNDPFGGWVIWTALPGEGLSGATIVRGAGAGPYGAGALTGVVVLRERAVGGGLS-SFTAQAGQRDSWRAAGTF 166
Cdd:COG1629 74 VLVDGVPLNDPSGGDGGLSYIDPEDIERVEVLRGPSSALYGSGALGGVINIVTKKPKDGKGgEVSASYGSYGTYRASLSL 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 947383669 167 --GTDHL--LLTASGSRTDGYRP--------VRGAAVGAADAPTTLE--------DGSIAARVQGELGDVRWAVRAGafQ 226
Cdd:COG1629 154 sgGNGKLayRLSASYRDSDGYRDnsdsdrynLRAKLGYQLGDDTRLTlsasysdsDQDSPGYLTLAALRPRGAMDDG--T 231
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 947383669 227 EKRGAGLVGARSNATGGSLAVTLAGEAWRLQAWARSSDLENTSAAVAAGRVGTTPANDQYSTPASGYGLNAAWQHK---A 303
Cdd:COG1629 232 NPYSNDTDDNTRDRYSLSLEYEHLGDGLKLSASAYYRYDDTDLDSDFTPTPADGGTLEQTDFDNRTYGLELRLTYDlgfG 311
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 947383669 304 GDWSWELGGDVRATEGRTNELFRYMAGAFTRQRTAG----GRTLVGGLYAETAYA-REDFSLTAGARLDGWrsyagvRRE 378
Cdd:COG1629 312 GKHTLLVGLDYQRQDLDGSGYPLDLGSGSLPTLTSGadddGTTTSLALYAQDTYKlTDKLTLTAGLRYDYV------SYD 385
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 947383669 379 RDAATGALTLDAPPADASGTTPtaRIGVRQRVSGETWWRAAAYAGFRPPTLNELhrPFRVGNDVTEANAALKPETLYGLE 458
Cdd:COG1629 386 VDDTVTGTDSASGSRSYSAFSP--SLGLTYQLSPNLSLYASYSRGFRAPTFGEL--YANGTDPYSVGNPDLKPETSTNYE 461
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 947383669 459 TGLAGE---GAVRWTLGAFYNQVQDPITNVTIGVGpgtfpiagfipaGGVLRQRRNAGEISAYGLEGDMAADLSPAWTVR 535
Cdd:COG1629 462 LGLRYRlldGRLSLSLALFYSDVDNEILSVPLPND------------SGFSTYYTNAGKARSYGVELELSYQLTPGLSLN 529
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 947383669 536 AAFSATHARVD----GAAQLTGKRPAQAPALTVTAGARWRPIERLSLDADLRYESKRFEDDLNTRTLKAGAGL-DLRVGW 610
Cdd:COG1629 530 ASYSYTDAKFDddtdGSADLDGNRLPGVPPLTANLGLTYEFPGGWSLGLGVRYVGDRYLDDANTQGAPGGYTLvDLGAGY 609
|
650 660 670
....*....|....*....|....*....|...
gi 947383669 611 KVSPTSEIYLAADNALDADLAVGQTADGVTSYS 643
Cdd:COG1629 610 RFGDNLTLSLGVDNLFDKKYATSLSVRASNVRG 642
|
|
| ligand_gated_channel |
cd01347 |
TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) ... |
40-652 |
9.18e-33 |
|
TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel. Energy (proton-motive force) and TonB-dependent conformational alteration of channel (parts of plug, and loops 7 and 8) allow passage of ligand. FepA residues 12-18 form the TonB box, which mediates the interaction with the TonB-containing inner membrane complex. TonB preferentially interacts with ligand-bound receptors. Transport thru the channel may resemble passage thru an air lock. In this model, ligand binding leads to closure of the extracellular end of pore, then a TonB-mediated signal facillitates opening of the interior side of pore, deforming the N-terminal plug and allowing passage of the ligand to the periplasm. Such a mechanism would prevent the free diffusion of small molecules thru the pore.
Pssm-ID: 238657 [Multi-domain] Cd Length: 635 Bit Score: 134.12 E-value: 9.18e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 947383669 40 SGQTRLDDVLKTTPGVSLFRRTGSDAANPTIQGLslravapsGAGRALVTLDGAPQNDPFGG--WVIWTaLPGEGLSGAT 117
Cdd:cd01347 13 QPATSLADLLRRIPGVSVTRGGGGGGSTISIRGF--------GPDRTLVLVDGLPLASSNYGrgVDLNT-IPPELIERVE 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 947383669 118 IVRGAGAGPYGAGALTGVV-VLRERAVGGGLSSFTAQAGQRDSW----------RAAGTFGTDHLLLTASGSRTDGYRPV 186
Cdd:cd01347 84 VLKGPSSALYGSGAIGGVVnIITKRPTDEFGGSVTAGYGSDNSGssggggfdvsGALADDGAFGARLYGAYRDGDGTIDG 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 947383669 187 RGAAvgaadAPTTLEDGSIAARVQGELGD-VRWAVRAGAFQEK----RGAGLVGARSNATGGSLAVTLAG---------- 251
Cdd:cd01347 164 DGQA-----DDSDEERYNVAGKLDWRPDDdTRLTLDAGYQDQDadgpGGTLPANGTGSSLGGGPSSNTNGdrdwdyrdry 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 947383669 252 --------------EAWRLQAWARSSDLENTSaaVAAGRVGTTPANDQYSTPASGY------------GLNAAWQHKAGD 305
Cdd:cd01347 239 rkraslglehdlndTGWTLRANLSYSYTDNDG--DPLILNGGNNAAGGDLGRSGYSserdttqlgfdaGLNAPFGTGPVA 316
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 947383669 306 WSWELGGDVRATEGRTNelfrymagaftrqrtaggrtlVGGLYAETAY-AREDFSLTAGARLDGWRSYagvrrerdaaTG 384
Cdd:cd01347 317 HTLTLGVEYRREELDEK---------------------QTALYAQDTIeLTDDLTLTLGLRYDHYDQD----------SK 365
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 947383669 385 ALTLDAPPADASGTTPTARIGVRQRVSGETWWRAAAYAGFRPPTLNELHRPFRVGNDVTEANAALKPETLYGLETGLAGE 464
Cdd:cd01347 366 DTIAGGTTAKKSYSHWSPSLGLVYKLTDGLSLYASYSQGFRAPSLGELYGGGSHGGTAAVGNPNLKPEKSKQYELGLKYD 445
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 947383669 465 GAVRW--TLGAFYNQVQDPITNVTIGVGPGTfpiagfipaggvLRQRRNAGEISAYGLEGDMAADLSPAWTVRAAFSATH 542
Cdd:cd01347 446 PGDGLtlSAALFRIDIKNEIVSTPTNTGLGL------------VTVYVNGGKARIRGVELEASYDLTDGLGLTGSYTYTD 513
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 947383669 543 ARV-DGAAQLTGKRPAQAPALTVTAGARW-RPIERLSLDADLRYESKRFEDD---LNTRTLKAGAGLDLRVGWKVSPTSE 617
Cdd:cd01347 514 TEVkRTDGATTGNRLPGIPKHTANLGLDYeLPDEGLTAGGGVRYRGKQYADTangNNTVKVPGYTLVDLSASYQFTKNLT 593
|
650 660 670
....*....|....*....|....*....|....*...
gi 947383669 618 IYLAADNALDADL---AVGQTADGVTSYSAPRTIYVGF 652
Cdd:cd01347 594 LRLGVNNLFDKDYytsLSVRGSGLYGYYGPGRTYYLSV 631
|
|
| TonB_dep_Rec |
pfam00593 |
TonB dependent receptor; This model now only covers the conserved part of the barrel structure. |
258-655 |
1.24e-27 |
|
TonB dependent receptor; This model now only covers the conserved part of the barrel structure.
Pssm-ID: 395474 [Multi-domain] Cd Length: 475 Bit Score: 116.79 E-value: 1.24e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 947383669 258 AWARSSDLENTSAAVAAGRVGTTPANDQYSTPA----SGYGLNAAWQHKAGDWSWELGGDVRATEGRTNELFRYMAGAFT 333
Cdd:pfam00593 86 RYSSLDGDYTSNSSGLSGAGDYLSDDRLYGLYGldgdLELSLDLSHDLLLGVELRTAGLDYRRLDDDAYDPYDPANPSSS 165
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 947383669 334 RQRTAGGRTLvgGLYAETAYA-REDFSLTAGARLDGWRSYAGVRRERDAATGAltldappaDASGTTPtaRIGVRQRVSG 412
Cdd:pfam00593 166 SYSDTTTDSY--GLYLQDNIKlTDRLTLTLGLRYDHYSTDGDDGNGGGDNFSR--------SYSAFSP--RLGLVYKPTD 233
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 947383669 413 ETWWRAAAYAGFRPPTLNELHRPFRVGNDVTEA--NAALKPETLYGLETGL-AGEGAVRWTLGAFYNQVQDPITNVTIGV 489
Cdd:pfam00593 234 NLSLYASYSRGFRAPSLGELYGSGSGGGGGAVAggNPDLKPETSDNYELGLkYDDGRLSLSLALFYIDIKNLITSDPDGP 313
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 947383669 490 GPGTFPIagfipaggvlrQRRNAGEISAYGLEGDMAADLSPAWTVRAAFSATHARVDGAAQLTGKRPAQAPALTVTAGAR 569
Cdd:pfam00593 314 GLGGTVY-----------TYTNVGKARIRGVELELSGRLWGLGLSGGGYTYTDADDDADADDTGNPLPNVPRHTANLGLT 382
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 947383669 570 WR-PIERLSLDADLRY--ESKRFEDDLNTRTLKAGAGL-DLRVGWKVSPTSEIYLAADNALDADL---AVGQTADGVTSY 642
Cdd:pfam00593 383 YDfPLGGWGARLGARYvgSGERRYGDAANTFKTPGYTLvDLSAGYRLNKNLTLRLGVNNLFDKYYkryYSSGGGNLGGYP 462
|
410
....*....|...
gi 947383669 643 SAPRTIYVGFALR 655
Cdd:pfam00593 463 GPGRTFYLGLSYK 475
|
|
| TonB-siderophor |
TIGR01783 |
TonB-dependent siderophore receptor; This subfamily model encompasses a wide variety of ... |
9-651 |
3.21e-16 |
|
TonB-dependent siderophore receptor; This subfamily model encompasses a wide variety of TonB-dependent outer membrane siderophore receptors. It has no overlap with TonB receptors known to transport other substances, but is likely incomplete due to lack of characterizations. It is likely that genuine siderophore receptors will be identified which score below the noise cutoff to this model at which point the model should be updated. [Transport and binding proteins, Cations and iron carrying compounds, Transport and binding proteins, Porins]
Pssm-ID: 273805 [Multi-domain] Cd Length: 651 Bit Score: 82.46 E-value: 3.21e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 947383669 9 PVSAIVVEAPRLpslagqeafstatydarALSGQTRLDDVLKTTPGVSL-FRRTGSDAANPTIQGLSLRAVAPSgagral 87
Cdd:TIGR01783 3 PQSVSVITRQEL-----------------EDQQAGSLSEALQRVPGVVVgGSGGTTQFGNITIRGFGLEVDIDN------ 59
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 947383669 88 VTLDGAPQNDPFGGWVIWTALpgegLSGATIVRGAGAGPYGAGALTGVVVL-RERAVGGGLSSFTAQAGQRDSWRAAGTF 166
Cdd:TIGR01783 60 VYLDGVPLLSRGNLAIVDPAM----VERVEVLRGPASLLYGGSAPGGVINIvTKRPQDEPKGSVTFGAGTRSGYRTAFDL 135
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 947383669 167 G-----TDHLLLTASGSRT--DGYRPVRGAAVGA-ADAPTTLEDGSIAARVQGELGDVRWAVRAGAFQEKRGAGLVGARS 238
Cdd:TIGR01783 136 GgplgaDGTFRGRLNGARQdgDSFYDGAGEETRLgATATDWQLDDRTLLRLGAYYQKERDRGGYGGLPASGGTSGRDLSS 215
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 947383669 239 NATGGSLAVTLAGEAWRL-----------QAWARSSDL---ENTSAAVAAGRVGTTPANDQYstpasGYGLNAAWQ-HKA 303
Cdd:TIGR01783 216 DRYLGTSSNRNYDDREYLsyglsleyqfnDVWTGKQNLrysYFDTDSNQVQASGYSSDGGLF-----GRSLTVVNVkQDR 290
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 947383669 304 GDWSWELGGDVRaTEGRTNELF--------------------------------RYMAGAFTRQRTAGGRTLVGGLYAET 351
Cdd:TIGR01783 291 VQIDAGLDGEFE-TGPIEHDLLlgvsygqrttnrfnntgypsdniysltatssaRTDIGDSPKDRALSSTTKALNGVALQ 369
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 947383669 352 AYARED-FSLTAGARLDGWRSYAGVRRERDAATGaltldappadaSGTTPTARIGVRQRVSGETWWRAAAYAGFRPPTLN 430
Cdd:TIGR01783 370 RILLADkWTLTLGGRYDSVDVKSNNGVAGSTGKR-----------DDSQFTPSLGVAYKPTDDWSLYASYAESFKPGGYY 438
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 947383669 431 ELhrpfrvgnDVTEANAALKPETLYGLETGLAGEGAVRWTL-GAFYNQVQDpiTNVTIGVGPGTFPIagfipaggvlrqr 509
Cdd:TIGR01783 439 PK--------GAGNSGDILEPEKGKNYELGVRYDLGDSLLAtAALFRITKD--NQLVQDPVNGTFSV------------- 495
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 947383669 510 rNAGEISAYGLEGDMAADLSPAWTVRAAFSATHARV--DGAAQLTGKRPAQAPALTVTAGARWRPIE---RLSLDADLRY 584
Cdd:TIGR01783 496 -NAGKTRNRGVELEARGYLTPGLSLSAGYTYTDAEFteDTNGDTQGNTVPFVPKHTASLWASYAPPVgdnGLTLGGGVQY 574
|
650 660 670 680 690 700 710
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 947383669 585 ESKRFEDDLNTRTLKAGAGLDLRVGWKV--SPTSEIYLAADNALDADL--AVGQ-TADGVTSYSAPRTIYVG 651
Cdd:TIGR01783 575 TGKAYVDGGNTGKVPSYTVVDLSVRYDLtkKKNLTLALNVNNLFDRDYytSGYRwGPSAYIYPGAPRTVGLS 646
|
|
| PRK13483 |
PRK13483 |
ligand-gated channel protein; |
347-630 |
4.46e-08 |
|
ligand-gated channel protein;
Pssm-ID: 184080 [Multi-domain] Cd Length: 660 Bit Score: 56.32 E-value: 4.46e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 947383669 347 LYAETAYA-REDFSLTAGARLDGWRSYAGVRRERdaATGALTLdappadasgttpTARIGVRQRVSgetwwraaayAGFR 425
Cdd:PRK13483 374 VFSEDEWRiADDFALTGGLRLDHDENFGGHVSPR--VYGVWNL------------APSWTVKGGVS----------TGFR 429
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 947383669 426 PPTLNELHRPF----RVGNdvTEANAALKPETLYGLETGL---AGEGaVRWTLGAFYNQVQDPITNVtigVGPGTFPIAG 498
Cdd:PRK13483 430 APSLRQTTPDWgqvsRGGN--IYGNPDLKPETSLNKELGLyydLGSG-LTASLTVFYNEFKDKITRV---ACPATQCTDG 503
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 947383669 499 FIPAGGVLRQRRNAGEISAYGLEGDMAADLSPAWTVRAAFSATHARvDGAAQLTGKRPAQAPALTVTAGARWRPIERLSL 578
Cdd:PRK13483 504 PNQFGADPTTYVNIDEAVTQGVEASLSYPITSTLSLSGNYTYTDSE-QKSGAYKGSPLNQLPKHLFQASLNWEPTDRLNS 582
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*.
gi 947383669 579 DADLRYESKRFED----DLNTRTLKAGAGLDLRVGWKVSPTSEIYLAADNALDADL 630
Cdd:PRK13483 583 WARVNYRGEESQPttgpSSSSFIAPSYTFLDLGANYQLTDNLKLSAGIYNLFDKEI 638
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| CirA |
COG1629 |
Outer membrane receptor protein, Fe transport [Inorganic ion transport and metabolism]; |
10-643 |
7.38e-52 |
|
Outer membrane receptor protein, Fe transport [Inorganic ion transport and metabolism];
Pssm-ID: 441236 [Multi-domain] Cd Length: 644 Bit Score: 189.65 E-value: 7.38e-52
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 947383669 10 VSAIVVEAPRLPSLAGQEAFSTATYDARALSGQ--TRLDDVLKTTPGVSlFRRTGSDAANPTIQGLSlravapSGAGRAL 87
Cdd:COG1629 1 LEEVVVTATRTDESLQDVPGSVSVISREQLEDQpaTDLGDLLRRVPGVS-VTSAGGGAGQISIRGFG------GGGNRVL 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 947383669 88 VTLDGAPQNDPFGGWVIWTALPGEGLSGATIVRGAGAGPYGAGALTGVVVLRERAVGGGLS-SFTAQAGQRDSWRAAGTF 166
Cdd:COG1629 74 VLVDGVPLNDPSGGDGGLSYIDPEDIERVEVLRGPSSALYGSGALGGVINIVTKKPKDGKGgEVSASYGSYGTYRASLSL 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 947383669 167 --GTDHL--LLTASGSRTDGYRP--------VRGAAVGAADAPTTLE--------DGSIAARVQGELGDVRWAVRAGafQ 226
Cdd:COG1629 154 sgGNGKLayRLSASYRDSDGYRDnsdsdrynLRAKLGYQLGDDTRLTlsasysdsDQDSPGYLTLAALRPRGAMDDG--T 231
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 947383669 227 EKRGAGLVGARSNATGGSLAVTLAGEAWRLQAWARSSDLENTSAAVAAGRVGTTPANDQYSTPASGYGLNAAWQHK---A 303
Cdd:COG1629 232 NPYSNDTDDNTRDRYSLSLEYEHLGDGLKLSASAYYRYDDTDLDSDFTPTPADGGTLEQTDFDNRTYGLELRLTYDlgfG 311
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 947383669 304 GDWSWELGGDVRATEGRTNELFRYMAGAFTRQRTAG----GRTLVGGLYAETAYA-REDFSLTAGARLDGWrsyagvRRE 378
Cdd:COG1629 312 GKHTLLVGLDYQRQDLDGSGYPLDLGSGSLPTLTSGadddGTTTSLALYAQDTYKlTDKLTLTAGLRYDYV------SYD 385
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 947383669 379 RDAATGALTLDAPPADASGTTPtaRIGVRQRVSGETWWRAAAYAGFRPPTLNELhrPFRVGNDVTEANAALKPETLYGLE 458
Cdd:COG1629 386 VDDTVTGTDSASGSRSYSAFSP--SLGLTYQLSPNLSLYASYSRGFRAPTFGEL--YANGTDPYSVGNPDLKPETSTNYE 461
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 947383669 459 TGLAGE---GAVRWTLGAFYNQVQDPITNVTIGVGpgtfpiagfipaGGVLRQRRNAGEISAYGLEGDMAADLSPAWTVR 535
Cdd:COG1629 462 LGLRYRlldGRLSLSLALFYSDVDNEILSVPLPND------------SGFSTYYTNAGKARSYGVELELSYQLTPGLSLN 529
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 947383669 536 AAFSATHARVD----GAAQLTGKRPAQAPALTVTAGARWRPIERLSLDADLRYESKRFEDDLNTRTLKAGAGL-DLRVGW 610
Cdd:COG1629 530 ASYSYTDAKFDddtdGSADLDGNRLPGVPPLTANLGLTYEFPGGWSLGLGVRYVGDRYLDDANTQGAPGGYTLvDLGAGY 609
|
650 660 670
....*....|....*....|....*....|...
gi 947383669 611 KVSPTSEIYLAADNALDADLAVGQTADGVTSYS 643
Cdd:COG1629 610 RFGDNLTLSLGVDNLFDKKYATSLSVRASNVRG 642
|
|
| FepA |
COG4771 |
Outer membrane receptor for ferrienterochelin and colicins [Inorganic ion transport and ... |
3-619 |
5.84e-46 |
|
Outer membrane receptor for ferrienterochelin and colicins [Inorganic ion transport and metabolism];
Pssm-ID: 443803 [Multi-domain] Cd Length: 612 Bit Score: 172.35 E-value: 5.84e-46
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 947383669 3 LEAPPSPVSAIVVEAPRLPSLAGQEAFSTATYDARAL--SGQTRLDDVLKTTPGVSLFRRTGSDAAN-PTIQGLslrava 79
Cdd:COG4771 20 LAEDATELEEVVVTATRTEQSLSDAPASVSVITAEEIekLGATDLADALRLLPGVSVTRSGGRGGSSgISIRGL------ 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 947383669 80 psGAGRALVTLDGAPQNDP-FGGWVIWTALPGEGLSGATIVRGAGAGPYGAGALTGVV-VLRERAVGGGLSSFTAQAGQR 157
Cdd:COG4771 94 --GGDRVLVLIDGVPVNNPaLGGGGDLSYIPPDDIERIEVIRGPASALYGSDAIGGVInIITKKPTDELEGSVSLGYGSN 171
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 947383669 158 D------SWRAAGTFGTDHLLLTASGSRTDGYRPVRGaavGAADAPTTLEDGSIAARVQGELGD-VRWAVRAGAFQEKRG 230
Cdd:COG4771 172 GngtysgSLSLGGPGDKLSFLLSGSYRDRDGYLDYRN---GGFVGNSGYERYNLNAKLGYRLSDnHRLSLSGGYSRQDRD 248
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 947383669 231 AGLVGARSNA-------------TGGSLAVTLAGE-AWRLQAWARSSDLENTSAAVAAGRVGTTPANDQYSTpasgYGLN 296
Cdd:COG4771 249 GGPPTLGDTEissdnagdrdtttDRGNYSLRYNGDlGDNLDLSLYYSRTDRDSTNGSLGGSTGSFSDSDDTT----YGLE 324
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 947383669 297 AAWQHK-AGDWSWELGGDVRATEGRTNelfrymagafTRQRTAGGRTLVGGLYAETAYA-REDFSLTAGARLDGWRSYAg 374
Cdd:COG4771 325 LDLTYPlGGNHTLTLGAEYRYDDLDSS----------SFLGGADASRDTYGLFAQDEWKlTDKLTLTAGLRYDYYSTFG- 393
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 947383669 375 vrrerdaatgaltldappaDASGTTPTARIGVRQRVSGETWWRAAAYAGFRPPTLNELHRPFR-VGNDVTEANAALKPET 453
Cdd:COG4771 394 -------------------ASNYTAFSPRLGLRYDLSDNLTLRASYGRGFRAPSLAELYGSGTgTPGRYVLGNPDLKPET 454
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 947383669 454 LYGLETGL---AGEGAVRWTLGAFYNQVQDPITNVTIGvgpgtfpiagfiPAGGVLRQRRNAGEISAYGLEGDMAADLSP 530
Cdd:COG4771 455 SDNYELGLeyrLGNGGLSLSLTGFYTDIKDLIVLVPVG------------PGPGDVLQYENVGKARTYGLELELKYRLGK 522
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 947383669 531 AWTVRAAFSATHARVDgaAQLTGKRPAQAPALTVTAGARWRPIERLSLDADLRYESKRFEDDLNTRTLKAGAG---LDLR 607
Cdd:COG4771 523 GLTLTASYTYLDSKID--DGDTGEPLPNVPPHKANLGLDYRLPKWWLLLLLTRYYGGRYVTPPSGRLEGYTPGytlLDLR 600
|
650
....*....|..
gi 947383669 608 VGWKVSPTSEIY 619
Cdd:COG4771 601 ASYKLTKNLTLS 612
|
|
| ligand_gated_channel |
cd01347 |
TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) ... |
40-652 |
9.18e-33 |
|
TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel. Energy (proton-motive force) and TonB-dependent conformational alteration of channel (parts of plug, and loops 7 and 8) allow passage of ligand. FepA residues 12-18 form the TonB box, which mediates the interaction with the TonB-containing inner membrane complex. TonB preferentially interacts with ligand-bound receptors. Transport thru the channel may resemble passage thru an air lock. In this model, ligand binding leads to closure of the extracellular end of pore, then a TonB-mediated signal facillitates opening of the interior side of pore, deforming the N-terminal plug and allowing passage of the ligand to the periplasm. Such a mechanism would prevent the free diffusion of small molecules thru the pore.
Pssm-ID: 238657 [Multi-domain] Cd Length: 635 Bit Score: 134.12 E-value: 9.18e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 947383669 40 SGQTRLDDVLKTTPGVSLFRRTGSDAANPTIQGLslravapsGAGRALVTLDGAPQNDPFGG--WVIWTaLPGEGLSGAT 117
Cdd:cd01347 13 QPATSLADLLRRIPGVSVTRGGGGGGSTISIRGF--------GPDRTLVLVDGLPLASSNYGrgVDLNT-IPPELIERVE 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 947383669 118 IVRGAGAGPYGAGALTGVV-VLRERAVGGGLSSFTAQAGQRDSW----------RAAGTFGTDHLLLTASGSRTDGYRPV 186
Cdd:cd01347 84 VLKGPSSALYGSGAIGGVVnIITKRPTDEFGGSVTAGYGSDNSGssggggfdvsGALADDGAFGARLYGAYRDGDGTIDG 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 947383669 187 RGAAvgaadAPTTLEDGSIAARVQGELGD-VRWAVRAGAFQEK----RGAGLVGARSNATGGSLAVTLAG---------- 251
Cdd:cd01347 164 DGQA-----DDSDEERYNVAGKLDWRPDDdTRLTLDAGYQDQDadgpGGTLPANGTGSSLGGGPSSNTNGdrdwdyrdry 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 947383669 252 --------------EAWRLQAWARSSDLENTSaaVAAGRVGTTPANDQYSTPASGY------------GLNAAWQHKAGD 305
Cdd:cd01347 239 rkraslglehdlndTGWTLRANLSYSYTDNDG--DPLILNGGNNAAGGDLGRSGYSserdttqlgfdaGLNAPFGTGPVA 316
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 947383669 306 WSWELGGDVRATEGRTNelfrymagaftrqrtaggrtlVGGLYAETAY-AREDFSLTAGARLDGWRSYagvrrerdaaTG 384
Cdd:cd01347 317 HTLTLGVEYRREELDEK---------------------QTALYAQDTIeLTDDLTLTLGLRYDHYDQD----------SK 365
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 947383669 385 ALTLDAPPADASGTTPTARIGVRQRVSGETWWRAAAYAGFRPPTLNELHRPFRVGNDVTEANAALKPETLYGLETGLAGE 464
Cdd:cd01347 366 DTIAGGTTAKKSYSHWSPSLGLVYKLTDGLSLYASYSQGFRAPSLGELYGGGSHGGTAAVGNPNLKPEKSKQYELGLKYD 445
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 947383669 465 GAVRW--TLGAFYNQVQDPITNVTIGVGPGTfpiagfipaggvLRQRRNAGEISAYGLEGDMAADLSPAWTVRAAFSATH 542
Cdd:cd01347 446 PGDGLtlSAALFRIDIKNEIVSTPTNTGLGL------------VTVYVNGGKARIRGVELEASYDLTDGLGLTGSYTYTD 513
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 947383669 543 ARV-DGAAQLTGKRPAQAPALTVTAGARW-RPIERLSLDADLRYESKRFEDD---LNTRTLKAGAGLDLRVGWKVSPTSE 617
Cdd:cd01347 514 TEVkRTDGATTGNRLPGIPKHTANLGLDYeLPDEGLTAGGGVRYRGKQYADTangNNTVKVPGYTLVDLSASYQFTKNLT 593
|
650 660 670
....*....|....*....|....*....|....*...
gi 947383669 618 IYLAADNALDADL---AVGQTADGVTSYSAPRTIYVGF 652
Cdd:cd01347 594 LRLGVNNLFDKDYytsLSVRGSGLYGYYGPGRTYYLSV 631
|
|
| FecA |
COG4772 |
Outer membrane receptor for Fe3+-dicitrate [Inorganic ion transport and metabolism]; |
4-655 |
2.71e-28 |
|
Outer membrane receptor for Fe3+-dicitrate [Inorganic ion transport and metabolism];
Pssm-ID: 443804 [Multi-domain] Cd Length: 681 Bit Score: 120.42 E-value: 2.71e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 947383669 4 EAPPSPVSAIVVEAPRLPSLAGQEAFSTATY-DARAL--SGQTRLDDVLKTTPGVSLFRRTGSdAANPTIqglSLRAVAP 80
Cdd:COG4772 17 AEAATTLETVVVTGSRAAEARLKDVPGSVSVvDREELenQAATSLREVLRRVPGVNVQEEDGF-GLRPNI---GIRGLGP 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 947383669 81 SGAGRALVTLDGAPQN-DPFGGWVIWTALPGEGLSGATIVRGAGAGPYGAGALTGVV--VLRE--RAVGGGLSsftAQAG 155
Cdd:COG4772 93 RRSRGITLLEDGIPIApAPYGDPAAYYFPDLERMERIEVLRGAAALRYGPQTVGGAInfVTRTipTAFGGELR---VTGG 169
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 947383669 156 QRDSWR----AAGTFGTDHLLLTASGSRTDGYRP----------VRGAAVGAADAPTTLEDGSIAARVQGELGDVRWAVR 221
Cdd:COG4772 170 SFGYRRthasVGGTVGNFGYLVEYSRKRGDGFRDnsgfdindfnAKLGYRLSDRQELTLKFQYYDEDANTPGGLTDAQFD 249
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 947383669 222 AGAFQEKRGAGLVGARSNATGGSLAVTLAGEA-WRLQAWA----RSSDLENTSAAVAAGRVGTTPANDQYSTpasgYGLN 296
Cdd:COG4772 250 ADPRQSYRPADQFDTRRTQLSLRYEHQLSDNTtLTTTAYYndfsRNWYIRQNTADPNTPGLGLRGNPRGYRS----YGIE 325
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 947383669 297 AAWqhkagDWSWELGGdvrategRTNEL---FRYMAGAFTRQRTAG-------GRTLVG---------GLYAETA-YARE 356
Cdd:COG4772 326 PRL-----THRFELGG-------VPHTLevgLRYHREEEDRKQYVNtygqgrsGAGLRRdrrfsadalAAYAQNRfELTG 393
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 947383669 357 DFSLTAGARldgwrsYAGVRRERDAATGALTLDAPPADASGTTPTARIGVRQRVSGETWWRAAAYAGFRPPTLNELhrpf 436
Cdd:COG4772 394 RLTLTPGLR------YEHIRRDRTDRYSTRTGGDDSGSNSYSEFLPGLGLLYQLTDNLQLYANVSRGFEPPTFGDL---- 463
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 947383669 437 rvgNDVTEANAALKPETLYGLETGL--AGEGAVRWTLGAFYNQVQDPITNVTIgvgpgtfpiagfipAGGVLRQRRNAGE 514
Cdd:COG4772 464 ---AYGNGGNPDLKPEKSWNYELGTrgRIGNGLSAEVALFYIDYDNELGSCSA--------------AGGDRSTFTNAGE 526
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 947383669 515 ISAYGLEGDMAADLSPA----WTVRAAFSATHARVDGA--AQLTGKRPAQAPALTVTAGARWRPiERLSLDADLRYESKR 588
Cdd:COG4772 527 TRHQGLELALDYDLLKGgglgLPLFAAYTYTDAEFTSDfgPVFAGNRLPYVPRHQLTAGLGYEH-GGWTANLNGRYVSEQ 605
|
650 660 670 680 690 700 710
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 947383669 589 FEDDLNTRTLKAGAG------LDLRVGWKVSPTSEIYLAADNALDADLAVGQTADGVTSY--SAPRTIYVGFALR 655
Cdd:COG4772 606 FTDAANTVADGSFGKipsytvLDLSASYDFGKNLSLFAGVNNLFDKRYIASRAPNYAAGIrpGPPRTVYAGLRLK 680
|
|
| TonB_dep_Rec |
pfam00593 |
TonB dependent receptor; This model now only covers the conserved part of the barrel structure. |
258-655 |
1.24e-27 |
|
TonB dependent receptor; This model now only covers the conserved part of the barrel structure.
Pssm-ID: 395474 [Multi-domain] Cd Length: 475 Bit Score: 116.79 E-value: 1.24e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 947383669 258 AWARSSDLENTSAAVAAGRVGTTPANDQYSTPA----SGYGLNAAWQHKAGDWSWELGGDVRATEGRTNELFRYMAGAFT 333
Cdd:pfam00593 86 RYSSLDGDYTSNSSGLSGAGDYLSDDRLYGLYGldgdLELSLDLSHDLLLGVELRTAGLDYRRLDDDAYDPYDPANPSSS 165
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 947383669 334 RQRTAGGRTLvgGLYAETAYA-REDFSLTAGARLDGWRSYAGVRRERDAATGAltldappaDASGTTPtaRIGVRQRVSG 412
Cdd:pfam00593 166 SYSDTTTDSY--GLYLQDNIKlTDRLTLTLGLRYDHYSTDGDDGNGGGDNFSR--------SYSAFSP--RLGLVYKPTD 233
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 947383669 413 ETWWRAAAYAGFRPPTLNELHRPFRVGNDVTEA--NAALKPETLYGLETGL-AGEGAVRWTLGAFYNQVQDPITNVTIGV 489
Cdd:pfam00593 234 NLSLYASYSRGFRAPSLGELYGSGSGGGGGAVAggNPDLKPETSDNYELGLkYDDGRLSLSLALFYIDIKNLITSDPDGP 313
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 947383669 490 GPGTFPIagfipaggvlrQRRNAGEISAYGLEGDMAADLSPAWTVRAAFSATHARVDGAAQLTGKRPAQAPALTVTAGAR 569
Cdd:pfam00593 314 GLGGTVY-----------TYTNVGKARIRGVELELSGRLWGLGLSGGGYTYTDADDDADADDTGNPLPNVPRHTANLGLT 382
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 947383669 570 WR-PIERLSLDADLRY--ESKRFEDDLNTRTLKAGAGL-DLRVGWKVSPTSEIYLAADNALDADL---AVGQTADGVTSY 642
Cdd:pfam00593 383 YDfPLGGWGARLGARYvgSGERRYGDAANTFKTPGYTLvDLSAGYRLNKNLTLRLGVNNLFDKYYkryYSSGGGNLGGYP 462
|
410
....*....|...
gi 947383669 643 SAPRTIYVGFALR 655
Cdd:pfam00593 463 GPGRTFYLGLSYK 475
|
|
| Fiu |
COG4774 |
Outer membrane receptor for monomeric catechols [Inorganic ion transport and metabolism]; |
41-655 |
2.09e-21 |
|
Outer membrane receptor for monomeric catechols [Inorganic ion transport and metabolism];
Pssm-ID: 443806 [Multi-domain] Cd Length: 639 Bit Score: 98.80 E-value: 2.09e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 947383669 41 GQTRLDDVLKTTPGVSLFRRTGSDAANPTIQGLSlravapsgaGRALVTLDGAPQN-----DPFG--------Gwviwta 107
Cdd:COG4774 25 GATSLADALRNVPGVTFGAGEGGNGDSFSIRGFS---------ASGDIYVDGLRDPgqyrrDTFNlervevlkG------ 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 947383669 108 lPGEGLSGATivrgagagpygagALTGVV-VLRERAVGGGLSSFTAQAGQRDSWRAA----GTFGTDHLL-LTASGSRTD 181
Cdd:COG4774 90 -PASVLYGRG-------------SPGGVInLVTKRPTDEPFTEVTLTYGSDGQRRATldvnGPLGDDLAYrLNGMYRDSD 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 947383669 182 GYRPV-----RGAAVGAA---DAPTTLE------------DGSIAARVQGELGDVRWavragafqeKRGAGLVGARSNAT 241
Cdd:COG4774 156 SYRDGvdndrWGIAPSLTwrlGDRTRLTldyeyqdddrtpDYGVPAVANGRPVDVDR---------STFYGQPDDYSDSE 226
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 947383669 242 GGSLAVTLA---GEAWRLQAWARSSDLENT------SAAVAAGRVGTTPANDQYSTPASGYGLNAAWQHKAGDWSWEL-- 310
Cdd:COG4774 227 TDSATLRLEhdfNDNWTLRNALRYSDYDRDyrntypTGGNATGTVTRSAYRRDQDNDTLSNQTDLTGKFDTGGVKHTLla 306
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 947383669 311 GGDVRaTEGRTNELFRYMAGAFT-----------------RQRTAGGRTLVGGLYAE-TAYAREDFSLTAGARLDGWRSy 372
Cdd:COG4774 307 GVEYS-REDSDNARYSGGGTAPTvnlynpvygapvtgptlGGADNDSRTDTTGLYLQdTISLTDRWSLLAGLRYDRFDT- 384
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 947383669 373 agvrRERDAATGALTLDAppaDASGTTPtaRIGVRQRVSGETwwraAAYA----GFRPPTLNelhrpfrvgNDVTEANAA 448
Cdd:COG4774 385 ----DYTDRTTGATTSSY---DDSAFSP--RAGLVYKPTPNL----SLYAsystSFNPGGGA---------PSLSNAGQA 442
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 947383669 449 LKPETLYGLETGL---AGEGAVRWTLGAFYNQVQDPITnvTIGVGPGTFpiagfipaggvlrqrRNAGEISAYGLEGDMA 525
Cdd:COG4774 443 LDPEKSRQYEVGVkwdLLDGRLSLTAALFRIEKTNVRT--TDPANPGVY---------------VQTGEQRSRGVELEAT 505
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 947383669 526 ADLSPAWTVRAAFSATHARV--DGAAQLTGKRPAQAPALTVTAGARWR-PIERLSLDADLRYESKRFEDDLNTRTLKAGA 602
Cdd:COG4774 506 GELTPGWSVLAGYTYLDAEItkSANAANVGNRLPNVPRHSASLWTTYDlPLPGLTLGGGVRYVGSRYADAANTVKLPSYT 585
|
650 660 670 680 690
....*....|....*....|....*....|....*....|....*....|...
gi 947383669 603 GLDLRVGWKVSPTSEIYLAADNALDADLAVGQTADGVTSYSAPRTIYVGFALR 655
Cdd:COG4774 586 RFDAGASYRLNKNLTLRLNVNNLTDKRYYASAYGSGYVTPGAPRTVLLSASYR 638
|
|
| FhuE |
COG4773 |
Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid [Inorganic ion ... |
356-655 |
1.79e-18 |
|
Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid [Inorganic ion transport and metabolism];
Pssm-ID: 443805 [Multi-domain] Cd Length: 692 Bit Score: 89.57 E-value: 1.79e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 947383669 356 EDFSLTAGARLDGWRSYAGVRRERDAATgaltldappADASGTTPtaRIGVRQRVSGETwwraAAYA----GFRPptlne 431
Cdd:COG4773 424 DRLSLLLGGRYDWYETDSTNRLGGSTTS---------YDDSAFTP--RAGLVYDLTPGL----SLYAsyseSFEP----- 483
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 947383669 432 lhrpfrvGNDVTEANAALKPETLYGLETGLAGE---GAVRWTLgAFYNQVQDpitNVTIGVGPGTfpiagfipagGVLRQ 508
Cdd:COG4773 484 -------QSGADNNGNPLDPETGKQYEAGVKGElfdGRLNATL-AVFDITQK---NVATTDPDNP----------NFYVQ 542
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 947383669 509 rrnAGEISAYGLEGDMAADLSPAWTVRAAFSATHARV-DGAAQLTGKRPAQAPALTVTAGARWR----PIERLSLDADLR 583
Cdd:COG4773 543 ---VGEVRSRGVELELSGELTPGLNLIAGYTYTDAKItKDADALEGKRLTNVPRHTASLWTTYRfpsgALKGLGLGGGVR 619
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 947383669 584 YESKRFEDDLNTRTLKAGAGLDLRVGWKVSPTSEIYLAADNALDADLAVGQTADGVTSYSAPRTIYVGFALR 655
Cdd:COG4773 620 YVGERYGDAANTFTLPSYTLVDAGARYDLGKNWTLQLNVNNLFDKKYYASSGSRGYVYYGAPRNVRLSLSYK 691
|
|
| TonB-siderophor |
TIGR01783 |
TonB-dependent siderophore receptor; This subfamily model encompasses a wide variety of ... |
9-651 |
3.21e-16 |
|
TonB-dependent siderophore receptor; This subfamily model encompasses a wide variety of TonB-dependent outer membrane siderophore receptors. It has no overlap with TonB receptors known to transport other substances, but is likely incomplete due to lack of characterizations. It is likely that genuine siderophore receptors will be identified which score below the noise cutoff to this model at which point the model should be updated. [Transport and binding proteins, Cations and iron carrying compounds, Transport and binding proteins, Porins]
Pssm-ID: 273805 [Multi-domain] Cd Length: 651 Bit Score: 82.46 E-value: 3.21e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 947383669 9 PVSAIVVEAPRLpslagqeafstatydarALSGQTRLDDVLKTTPGVSL-FRRTGSDAANPTIQGLSLRAVAPSgagral 87
Cdd:TIGR01783 3 PQSVSVITRQEL-----------------EDQQAGSLSEALQRVPGVVVgGSGGTTQFGNITIRGFGLEVDIDN------ 59
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 947383669 88 VTLDGAPQNDPFGGWVIWTALpgegLSGATIVRGAGAGPYGAGALTGVVVL-RERAVGGGLSSFTAQAGQRDSWRAAGTF 166
Cdd:TIGR01783 60 VYLDGVPLLSRGNLAIVDPAM----VERVEVLRGPASLLYGGSAPGGVINIvTKRPQDEPKGSVTFGAGTRSGYRTAFDL 135
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 947383669 167 G-----TDHLLLTASGSRT--DGYRPVRGAAVGA-ADAPTTLEDGSIAARVQGELGDVRWAVRAGAFQEKRGAGLVGARS 238
Cdd:TIGR01783 136 GgplgaDGTFRGRLNGARQdgDSFYDGAGEETRLgATATDWQLDDRTLLRLGAYYQKERDRGGYGGLPASGGTSGRDLSS 215
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 947383669 239 NATGGSLAVTLAGEAWRL-----------QAWARSSDL---ENTSAAVAAGRVGTTPANDQYstpasGYGLNAAWQ-HKA 303
Cdd:TIGR01783 216 DRYLGTSSNRNYDDREYLsyglsleyqfnDVWTGKQNLrysYFDTDSNQVQASGYSSDGGLF-----GRSLTVVNVkQDR 290
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 947383669 304 GDWSWELGGDVRaTEGRTNELF--------------------------------RYMAGAFTRQRTAGGRTLVGGLYAET 351
Cdd:TIGR01783 291 VQIDAGLDGEFE-TGPIEHDLLlgvsygqrttnrfnntgypsdniysltatssaRTDIGDSPKDRALSSTTKALNGVALQ 369
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 947383669 352 AYARED-FSLTAGARLDGWRSYAGVRRERDAATGaltldappadaSGTTPTARIGVRQRVSGETWWRAAAYAGFRPPTLN 430
Cdd:TIGR01783 370 RILLADkWTLTLGGRYDSVDVKSNNGVAGSTGKR-----------DDSQFTPSLGVAYKPTDDWSLYASYAESFKPGGYY 438
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 947383669 431 ELhrpfrvgnDVTEANAALKPETLYGLETGLAGEGAVRWTL-GAFYNQVQDpiTNVTIGVGPGTFPIagfipaggvlrqr 509
Cdd:TIGR01783 439 PK--------GAGNSGDILEPEKGKNYELGVRYDLGDSLLAtAALFRITKD--NQLVQDPVNGTFSV------------- 495
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 947383669 510 rNAGEISAYGLEGDMAADLSPAWTVRAAFSATHARV--DGAAQLTGKRPAQAPALTVTAGARWRPIE---RLSLDADLRY 584
Cdd:TIGR01783 496 -NAGKTRNRGVELEARGYLTPGLSLSAGYTYTDAEFteDTNGDTQGNTVPFVPKHTASLWASYAPPVgdnGLTLGGGVQY 574
|
650 660 670 680 690 700 710
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 947383669 585 ESKRFEDDLNTRTLKAGAGLDLRVGWKV--SPTSEIYLAADNALDADL--AVGQ-TADGVTSYSAPRTIYVG 651
Cdd:TIGR01783 575 TGKAYVDGGNTGKVPSYTVVDLSVRYDLtkKKNLTLALNVNNLFDRDYytSGYRwGPSAYIYPGAPRTVGLS 646
|
|
| BtuB |
COG4206 |
Outer membrane cobalamin receptor protein BtuB [Coenzyme transport and metabolism]; |
13-280 |
8.41e-14 |
|
Outer membrane cobalamin receptor protein BtuB [Coenzyme transport and metabolism];
Pssm-ID: 443355 [Multi-domain] Cd Length: 276 Bit Score: 72.21 E-value: 8.41e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 947383669 13 IVVEAPRLPSLAGQEAFSTATYDARAL--SGQTRLDDVLKTTPGVSlFRRTGSDAANPTIqglSLRAVapsGAGRALVTL 90
Cdd:COG4206 1 VVVTATRLEQSKSDLTGSVTVIDAEELerSGATSLADALRRVPGVQ-VSSSGGPGSAASI---SIRGL---GSNQTLVLI 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 947383669 91 DGAPQNDPFGGWVIWTALPGEGLSGATIVRGAGAGPYGAGALTGVVVLRERAVGGGLS-SFTAQAGQRDSWRAAGTFGTD 169
Cdd:COG4206 74 DGVPLNDPSLGGVDLSLIPPDDIERIEVLKGAASALYGSDAIGGVINITTKKGKKGFKgSVSASYGSFGTRRLSASLSGG 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 947383669 170 ----HLLLTASGSRTDGYRPVRGAAVGAADapttLEDGSIAARVQGELGD-VRWAVRAGAFQEKRG--AGLVGARSNATG 242
Cdd:COG4206 154 agkfSYSLSASYRRSDGYRYNDPDLRNNDG----YENTSLNARLGYKLGDnGSLSLSGGYSDSERGypGAVGSDRNLRLS 229
|
250 260 270
....*....|....*....|....*....|....*...
gi 947383669 243 GSLAVTLAGEAWRLQAWARSSDLENTSAAVAAGRVGTT 280
Cdd:COG4206 230 LSLEYKLSDGWSLLLLAYYYYDRDYEDGGGDSAGTSNT 267
|
|
| TonB-hemlactrns |
TIGR01786 |
TonB-dependent hemoglobin/transferrin/lactoferrin receptor family protein; This model ... |
26-652 |
4.35e-08 |
|
TonB-dependent hemoglobin/transferrin/lactoferrin receptor family protein; This model represents a family of TonB-dependent outer membrane receptor/transporters acting on iron-containing proteins such as hemoglobin, transferrin and lactoferrin. Two subfamily models with a narrower scope are contained within this model, the heme/hemoglobin receptor family protein model (TIGR01785) and the transferrin/lactoferrin receptor family model (TIGR01776). Accessions which score above trusted to this model while not scoring above trusted to the more specific models are most likely to be hemoglobin transporters. Nearly all of the species containing trusted hits to this model have access to hemoglobin, transferrin or lactoferrin or related proteins in their biological niche. [Transport and binding proteins, Cations and iron carrying compounds, Transport and binding proteins, Porins]
Pssm-ID: 273808 [Multi-domain] Cd Length: 715 Bit Score: 56.27 E-value: 4.35e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 947383669 26 QEAFSTATYDARALSGQ--TRLDDVLKTTPGVSlFRRTGSDAAnptiQGLSLRAVAPSgagRALVTLDGAPQNDPFGG-- 101
Cdd:TIGR01786 20 VTPASVSVISREQLKSQqvRNLRDLLRYEPGVS-VVEGGRGGS----QGINIRGLDKN---RVAVLVDGIRQNTSYGGqg 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 947383669 102 --WVIWTALPGEGLSGATIVRGAGAGPYGAGALTGVV---------VLRERAVGGGLSSFTAQAGQRDSWRAAGTFG-TD 169
Cdd:TIGR01786 92 stFYAINSIDPELIKSIEIVKGASSSLYGSGALGGVVafrtkdaadLLKPGKDLGGLSKLGYSSANNRFTQSVAAAGrND 171
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 947383669 170 HLLLTASGSRTDGYRPVRGAAVGAADAPTTLEDGSIAARVQGELGDVRWAV----RAGAFQE--KRGAGLVGARSNA-TG 242
Cdd:TIGR01786 172 DVDALVQATYRRGHELKNGNKANIGNESKRSKPNPSDYKSQSFLAKLGWQLndahRLGLSLEytQTDYDEPEMTNTSyLT 251
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 947383669 243 GSLAVTLAGEAWRLQA---WARSSDL------ENT---SAAVAAGRVGTTPANDQYSTPASGYG---------------- 294
Cdd:TIGR01786 252 KPLGAPLLSSTVVLGDsktRDRRTGLdyelnpDNSwldTVKLALDKQYIQLYNYLNATSASDYPgvdkngrykdkydyyt 331
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 947383669 295 ----LNAAWQHKAGDWSWELGGDVRATEGRTNELFRYM-------AGAFTRQRTAGGRTLvgGLYAETAYARED-FSLTA 362
Cdd:TIGR01786 332 lgfdTNNKIEFSVHSLSLTYGLDRFKDKVSTGDSRRNLptaaynlYGYEGENRPVKGSNF--GLFLQDNIKLGDwLSLSA 409
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 947383669 363 GARLDgwrsyagvRRERDAATGALTLDAPPA-DASGTTPTARIGVrQRVsgeTWWRAAA-YA-GFRPPTLNELH---RPF 436
Cdd:TIGR01786 410 GLRYD--------HYKTDPKADESKDYGAISkTYSRWSPSLGLTY-KPT---PWLTLYYsYSqGFRAPSFDELYgtgAHP 477
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 947383669 437 RVGNDVTEANAALKPETLYGLETGLAGEG-AVRWTLGAFYNQVQDPItNVTIGVGPGTfPIAGFIPAGGVlrQRRNAGEI 515
Cdd:TIGR01786 478 GGGPYTFLPNPNLKPETSKNWEIGINLHFdQLDFKVSYFRNDYKDFI-DLGIGVTAKG-NMAQVGSNTIT--NYVNIDNA 553
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 947383669 516 SAYGLEGDMAADLSPAWTVRAAFSAT--HARVDGAAQLTGKRPAQAPALTVTAGARWR-PIERLSLDADLRYESKRFEDD 592
Cdd:TIGR01786 554 RIRGIELSGRYDLGSFFSGPDGWTTTlkYGYTKGKDSDTNPWLNAITPLKVVLGLGYDhPDEKWGVGLTLTFSGAKDAVD 633
|
650 660 670 680 690 700 710
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 947383669 593 L------------NTRTLKAGAGL-DLRVGWKVSPTSEIYLAADNALDAD----LAVGQTADGVTSYSAP-RTIYVGF 652
Cdd:TIGR01786 634 AyatyyengeaakAGPLRTPSYTVvDLYGYYKPNKNLTLRFGVYNLLDRKyttwESARQAGPLATGYTAPgRNYKASV 711
|
|
| PRK13483 |
PRK13483 |
ligand-gated channel protein; |
347-630 |
4.46e-08 |
|
ligand-gated channel protein;
Pssm-ID: 184080 [Multi-domain] Cd Length: 660 Bit Score: 56.32 E-value: 4.46e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 947383669 347 LYAETAYA-REDFSLTAGARLDGWRSYAGVRRERdaATGALTLdappadasgttpTARIGVRQRVSgetwwraaayAGFR 425
Cdd:PRK13483 374 VFSEDEWRiADDFALTGGLRLDHDENFGGHVSPR--VYGVWNL------------APSWTVKGGVS----------TGFR 429
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 947383669 426 PPTLNELHRPF----RVGNdvTEANAALKPETLYGLETGL---AGEGaVRWTLGAFYNQVQDPITNVtigVGPGTFPIAG 498
Cdd:PRK13483 430 APSLRQTTPDWgqvsRGGN--IYGNPDLKPETSLNKELGLyydLGSG-LTASLTVFYNEFKDKITRV---ACPATQCTDG 503
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 947383669 499 FIPAGGVLRQRRNAGEISAYGLEGDMAADLSPAWTVRAAFSATHARvDGAAQLTGKRPAQAPALTVTAGARWRPIERLSL 578
Cdd:PRK13483 504 PNQFGADPTTYVNIDEAVTQGVEASLSYPITSTLSLSGNYTYTDSE-QKSGAYKGSPLNQLPKHLFQASLNWEPTDRLNS 582
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*.
gi 947383669 579 DADLRYESKRFED----DLNTRTLKAGAGLDLRVGWKVSPTSEIYLAADNALDADL 630
Cdd:PRK13483 583 WARVNYRGEESQPttgpSSSSFIAPSYTFLDLGANYQLTDNLKLSAGIYNLFDKEI 638
|
|
| Plug |
pfam07715 |
TonB-dependent Receptor Plug Domain; The Plug domain has been shown to be an independently ... |
28-120 |
1.52e-06 |
|
TonB-dependent Receptor Plug Domain; The Plug domain has been shown to be an independently folding subunit of the TonB-dependent receptors. It acts as the channel gate, blocking the pore until the channel is bound by ligand. At this point it under goes conformational changes opens the channel.
Pssm-ID: 462243 [Multi-domain] Cd Length: 107 Bit Score: 47.26 E-value: 1.52e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 947383669 28 AFSTATYDARAL--SGQTRLDDVLKTTPGVSLFRRTGSDAANPTIQGLslravapsGAGRALVTLDGAPQNDPFGGWVIW 105
Cdd:pfam07715 6 PGSVSVVTAEDIedQGATNLADALRGVPGVSVSSGGGGGGSSISIRGF--------GSNRVLVLVDGVPLNSGGGGSVDL 77
|
90
....*....|....*
gi 947383669 106 TALPGEGLSGATIVR 120
Cdd:pfam07715 78 NSIDPEDIERVEVLK 92
|
|
| PRK14050 |
PRK14050 |
TonB-dependent siderophore receptor; |
441-611 |
8.80e-05 |
|
TonB-dependent siderophore receptor;
Pssm-ID: 237595 [Multi-domain] Cd Length: 728 Bit Score: 45.56 E-value: 8.80e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 947383669 441 DVTEANAALKPETLYGLETGLAGEGAvrWTLGAFYNQVQDpIT--NVTIGVgPGTFpiagfipaggvlrQRRNAGEISAY 518
Cdd:PRK14050 523 GTLASGPPLKPEEGEQYEAGIKYEPS--FIDGLITASVFQ-ITkkNVTVTD-PLTF-------------ASTQLGEVRSR 585
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 947383669 519 GLEGDMAADLSPAWTVRAAFSATHARV--DGAAQLTGKRPAQAPALT--------VTAGArwrpIERLSLDADLRYESKR 588
Cdd:PRK14050 586 GFELEGKVNLDDNWKALASFTYTDLEIteDANPSLIGNSPYLVPETQaslwldyaVTDGA----FEGVSLGAGVRYQGES 661
|
170 180
....*....|....*....|...
gi 947383669 589 FEDDLNTRTLKAGAGLDLRVGWK 611
Cdd:PRK14050 662 WADEANTLKVPAATLFDAAIRYE 684
|
|
| OMP_b-brl_3 |
pfam14905 |
Outer membrane protein beta-barrel family; This family includes proteins annotated as TonB ... |
427-588 |
3.94e-03 |
|
Outer membrane protein beta-barrel family; This family includes proteins annotated as TonB dependent receptors. But it is also likely to contain other membrane beta barrel proteins of other functions.
Pssm-ID: 434300 [Multi-domain] Cd Length: 407 Bit Score: 39.95 E-value: 3.94e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 947383669 427 PTLNELhRPFRVGND---VTEANAALKPETLYGLETGLAGEGavRWTLGAFYNQVQDPITNVTIgvgpgtfpiagFIPAG 503
Cdd:pfam14905 188 PSYWDL-NPFRNYSDpynYSQGNPNLKPEYTNSFELGYTYKW--KLSLSLSYRYTNDVIQQTFI-----------TDDND 253
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 947383669 504 GVLRQR-RNAGEISAYGLEGDMAADLSPAWTVRAAFSATHARVDGAAQLTGKRpaQAPALTVTAGARWRPIERLSLDADL 582
Cdd:pfam14905 254 NVTYTTyENLGKSNSYGLELSASFNPTKWWSLNGNLNGYYNKYKIDGSLNSDF--SNFGFNWNLNNTFTLPKGWSLQLNG 331
|
....*.
gi 947383669 583 RYESKR 588
Cdd:pfam14905 332 NYRSPR 337
|
|
| |
