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Conserved domains on  [gi|944375488|gb|ALL72212|]
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polymerase subunits gamma and tau, partial [Aeromonas sp. PDCDC-75]

Protein Classification

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
PRK12323 super family cl46901
DNA polymerase III subunit gamma/tau;
1-273 0e+00

DNA polymerase III subunit gamma/tau;


The actual alignment was detected with superfamily member PRK07994:

Pssm-ID: 481241 [Multi-domain]  Cd Length: 647  Bit Score: 574.89  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944375488   1 ALDQGRLHHAYLLSGTRGVGKTTIARILAKSLNCEQGISSHPCGVCDTCREIDQGNFVDLLEIDAASRTKVEDTRELLDN 80
Cdd:PRK07994  31 ALDLGRLHHAYLFSGTRGVGKTTIARLLAKGLNCETGITATPCGECDNCREIEQGRFVDLIEIDAASRTKVEDTRELLDN 110
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944375488  81 VQYRPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPPYVKFLLATTDPQKLPITILSRCLQFHLKSLDQTQIAKQLEWV 160
Cdd:PRK07994 111 VQYAPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPEHVKFLLATTDPQKLPVTILSRCLQFHLKALDVEQIRQQLEHI 190
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944375488 161 LDQEGQPFEPRALLALAKAADGSMRDALSLTDQALAHGNGSVRLESVLAMLGTLDHRHLHQLLEAILRQDAPATMAKITE 240
Cdd:PRK07994 191 LQAEQIPFEPRALQLLARAADGSMRDALSLTDQAIASGNGQVTTDDVSAMLGTLDDDQALSLLEALVEGDGERVMALINQ 270
                        250       260       270
                 ....*....|....*....|....*....|...
gi 944375488 241 IATLGPDFDQLHAELEGLLHRIAMAQLLPASVQ 273
Cdd:PRK07994 271 LAERGPDWEGLLVELLELLHRIAMAQLLPAALD 303
 
Name Accession Description Interval E-value
PRK07994 PRK07994
DNA polymerase III subunits gamma and tau; Validated
1-273 0e+00

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236138 [Multi-domain]  Cd Length: 647  Bit Score: 574.89  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944375488   1 ALDQGRLHHAYLLSGTRGVGKTTIARILAKSLNCEQGISSHPCGVCDTCREIDQGNFVDLLEIDAASRTKVEDTRELLDN 80
Cdd:PRK07994  31 ALDLGRLHHAYLFSGTRGVGKTTIARLLAKGLNCETGITATPCGECDNCREIEQGRFVDLIEIDAASRTKVEDTRELLDN 110
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944375488  81 VQYRPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPPYVKFLLATTDPQKLPITILSRCLQFHLKSLDQTQIAKQLEWV 160
Cdd:PRK07994 111 VQYAPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPEHVKFLLATTDPQKLPVTILSRCLQFHLKALDVEQIRQQLEHI 190
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944375488 161 LDQEGQPFEPRALLALAKAADGSMRDALSLTDQALAHGNGSVRLESVLAMLGTLDHRHLHQLLEAILRQDAPATMAKITE 240
Cdd:PRK07994 191 LQAEQIPFEPRALQLLARAADGSMRDALSLTDQAIASGNGQVTTDDVSAMLGTLDDDQALSLLEALVEGDGERVMALINQ 270
                        250       260       270
                 ....*....|....*....|....*....|...
gi 944375488 241 IATLGPDFDQLHAELEGLLHRIAMAQLLPASVQ 273
Cdd:PRK07994 271 LAERGPDWEGLLVELLELLHRIAMAQLLPAALD 303
dnaX_nterm TIGR02397
DNA polymerase III, subunit gamma and tau; This model represents the well-conserved first ~ ...
1-272 3.07e-136

DNA polymerase III, subunit gamma and tau; This model represents the well-conserved first ~ 365 amino acids of the translation of the dnaX gene. The full-length product of the dnaX gene in the model bacterium E. coli is the DNA polymerase III tau subunit. A translational frameshift leads to early termination and a truncated protein subunit gamma, about 1/3 shorter than tau and present in roughly equal amounts. This frameshift mechanism is not necessarily universal for species with DNA polymerase III but appears conserved in the exterme thermophile Thermus thermophilis. [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 274111 [Multi-domain]  Cd Length: 355  Bit Score: 388.46  E-value: 3.07e-136
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944375488    1 ALDQGRLHHAYLLSGTRGVGKTTIARILAKSLNCEQGISSHPCGVCDTCREIDQGNFVDLLEIDAASRTKVEDTRELLDN 80
Cdd:TIGR02397  29 AIKNGRIAHAYLFSGPRGTGKTSIARIFAKALNCQNGPDGEPCNECESCKEINSGSSLDVIEIDAASNNGVDDIREILDN 108
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944375488   81 VQYRPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPPYVKFLLATTDPQKLPITILSRCLQFHLKSLDQTQIAKQLEWV 160
Cdd:TIGR02397 109 VKYAPSSGKYKVYIIDEVHMLSKSAFNALLKTLEEPPEHVVFILATTEPHKIPATILSRCQRFDFKRIPLEDIVERLKKI 188
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944375488  161 LDQEGQPFEPRALLALAKAADGSMRDALSLTDQALAHGNGSVRLESVLAMLGTLDHRHLHQLLEAILRQDAPATMAKITE 240
Cdd:TIGR02397 189 LDKEGIKIEDEALELIARAADGSLRDALSLLDQLISFGNGKITYEDVNELLGLVDDEKLIELLEAILNKDTAEALKILDE 268
                         250       260       270
                  ....*....|....*....|....*....|..
gi 944375488  241 IATLGPDFDQLHAELEGLLHRIAMAQLLPASV 272
Cdd:TIGR02397 269 ILESGVDPEKFLEDLIEILRDLLLIKKTPSNL 300
DnaX COG2812
DNA polymerase III, gamma/tau subunits [Replication, recombination and repair];
1-271 3.05e-131

DNA polymerase III, gamma/tau subunits [Replication, recombination and repair];


Pssm-ID: 442061 [Multi-domain]  Cd Length: 340  Bit Score: 374.91  E-value: 3.05e-131
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944375488   1 ALDQGRLHHAYLLSGTRGVGKTTIARILAKSLNCEQGISSHPCGVCDTCREIDQGNFVDLLEIDA-ASRTKVEDTRELLD 79
Cdd:COG2812   25 ALASGRLAHAYLFTGPRGVGKTTLARILAKALNCENGPTGEPCGECESCRAIAAGSHPDVIEIDAeASNIGVDDIRELIE 104
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944375488  80 NVQYRPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPPYVKFLLATTDPQKLPITILSRCLQFHLKSLDQTQIAKQLEW 159
Cdd:COG2812  105 KVSYAPVEGRYKVYIIDEAHMLTTEAFNALLKTLEEPPPHVVFILATTEPQKLLPTILSRCQRFDFRRLPPEEIAEHLAK 184
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944375488 160 VLDQEGQPFEPRALLALAKAADGSMRDALSLTDQALAHGNGSVRlesvlamlgtldhRHLHQLLEAILRQDAPATMAKIT 239
Cdd:COG2812  185 IAEREGIEIEPEALALIARAADGSMRDALSLLDQAIAFGLLDRR-------------ELLLDLLEALLAGDVAALLALAE 251
                        250       260       270
                 ....*....|....*....|....*....|..
gi 944375488 240 EIATLGPDFDQLHAELEGLLHRIAMAQLLPAS 271
Cdd:COG2812  252 ELAKRGRDLKRFLDDLLSLLRDLLLLKLGPDA 283
DNA_pol3_delta2 pfam13177
DNA polymerase III, delta subunit; DNA polymerase III, delta subunit (EC 2.7.7.7) is required ...
1-149 8.94e-55

DNA polymerase III, delta subunit; DNA polymerase III, delta subunit (EC 2.7.7.7) is required for, along with delta' subunit, the assembly of the processivity factor beta(2) onto primed DNA in the DNA polymerase III holoenzyme-catalyzed reaction. The delta subunit is also known as HolA.


Pssm-ID: 433013 [Multi-domain]  Cd Length: 161  Bit Score: 174.32  E-value: 8.94e-55
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944375488    1 ALDQGRLHHAYLLSGTRGVGKTTIARILAKSLNCEQGISSHPCGVCDTCREIDQGNFVDLLEIDAASRT-KVEDTRELLD 79
Cdd:pfam13177  12 SLENGRLSHAYLFSGPEGVGKLELALAFAKALFCEEPGDDLPCGQCRSCRRIESGNHPDLVIIEPEGQSiKIDQIRELQK 91
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944375488   80 NVQYRPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPPYVKFLLATTDPQKLPITILSRCLQFHLKSLD 149
Cdd:pfam13177  92 EFSKSPYEGKKKVYIIEDAEKMTASAANSLLKFLEEPPGNTVIILLTENPSRLLPTIRSRCQIIRFKPLS 161
HLD_clamp_pol_III_gamma_tau cd18137
helical lid domain of DNA polymerase III subunits gamma and tau; DNA polymerase III subunit ...
148-212 2.86e-15

helical lid domain of DNA polymerase III subunits gamma and tau; DNA polymerase III subunit gamma/tau is part of the DNA polymerase III holoenzyme. Gamma and tau subunits are isoforms, both containing the helical lid domain. Gamma interacts with the delta subunit to transfer the beta subunit on the DNA while tau serves as a scaffold to help in the dimerization of the core complex. Both are members of the clamp-loader clade of the AAA+ superfamily.


Pssm-ID: 350839 [Multi-domain]  Cd Length: 65  Bit Score: 68.69  E-value: 2.86e-15
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 944375488 148 LDQTQIAKQLEWVLDQEGQPFEPRALLALAKAADGSMRDALSLTDQALAHGNGSVRLESVLAMLG 212
Cdd:cd18137    1 ISVEDIVGRLAHILEKEGIEIEDEALELIARAAEGSMRDALSLLDQAIAFGGGRVTLDDVREMLG 65
AAA smart00382
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ...
8-139 1.23e-06

ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.


Pssm-ID: 214640 [Multi-domain]  Cd Length: 148  Bit Score: 46.98  E-value: 1.23e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944375488     8 HHAYLLSGTRGVGKTTIARILAKSLNCEQGisshPCGVCDtCREIDQGNFVDLLEIDAASRTKVEDTRELLDNVQYRPAR 87
Cdd:smart00382   2 GEVILIVGPPGSGKTTLARALARELGPPGG----GVIYID-GEDILEEVLDQLLLIIVGGKKASGSGELRLRLALALARK 76
                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 944375488    88 GRFKVYLIDEVHMLSRHSFNALL-------KTLEEPPPYVKFLLATTDPQKLPITILSR 139
Cdd:smart00382  77 LKPDVLILDEITSLLDAEQEALLllleelrLLLLLKSEKNLTVILTTNDEKDLGPALLR 135
 
Name Accession Description Interval E-value
PRK07994 PRK07994
DNA polymerase III subunits gamma and tau; Validated
1-273 0e+00

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236138 [Multi-domain]  Cd Length: 647  Bit Score: 574.89  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944375488   1 ALDQGRLHHAYLLSGTRGVGKTTIARILAKSLNCEQGISSHPCGVCDTCREIDQGNFVDLLEIDAASRTKVEDTRELLDN 80
Cdd:PRK07994  31 ALDLGRLHHAYLFSGTRGVGKTTIARLLAKGLNCETGITATPCGECDNCREIEQGRFVDLIEIDAASRTKVEDTRELLDN 110
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944375488  81 VQYRPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPPYVKFLLATTDPQKLPITILSRCLQFHLKSLDQTQIAKQLEWV 160
Cdd:PRK07994 111 VQYAPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPEHVKFLLATTDPQKLPVTILSRCLQFHLKALDVEQIRQQLEHI 190
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944375488 161 LDQEGQPFEPRALLALAKAADGSMRDALSLTDQALAHGNGSVRLESVLAMLGTLDHRHLHQLLEAILRQDAPATMAKITE 240
Cdd:PRK07994 191 LQAEQIPFEPRALQLLARAADGSMRDALSLTDQAIASGNGQVTTDDVSAMLGTLDDDQALSLLEALVEGDGERVMALINQ 270
                        250       260       270
                 ....*....|....*....|....*....|...
gi 944375488 241 IATLGPDFDQLHAELEGLLHRIAMAQLLPASVQ 273
Cdd:PRK07994 271 LAERGPDWEGLLVELLELLHRIAMAQLLPAALD 303
PRK14949 PRK14949
DNA polymerase III subunits gamma and tau; Provisional
1-273 2.16e-145

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237863 [Multi-domain]  Cd Length: 944  Bit Score: 431.07  E-value: 2.16e-145
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944375488   1 ALDQGRLHHAYLLSGTRGVGKTTIARILAKSLNCEQGISSHPCGVCDTCREIDQGNFVDLLEIDAASRTKVEDTRELLDN 80
Cdd:PRK14949  31 ALTQQRLHHAYLFTGTRGVGKTSLARLFAKGLNCEQGVTATPCGVCSSCVEIAQGRFVDLIEVDAASRTKVDDTRELLDN 110
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944375488  81 VQYRPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPPYVKFLLATTDPQKLPITILSRCLQFHLKSLDQTQIAKQLEWV 160
Cdd:PRK14949 111 VQYRPSRGRFKVYLIDEVHMLSRSSFNALLKTLEEPPEHVKFLLATTDPQKLPVTVLSRCLQFNLKSLTQDEIGTQLNHI 190
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944375488 161 LDQEGQPFEPRALLALAKAADGSMRDALSLTDQALAHGNGSVRLESVLAMLGTLDHRHLHQLLEAILRQDAPATMAKITE 240
Cdd:PRK14949 191 LTQEQLPFEAEALTLLAKAANGSMRDALSLTDQAIAFGGGQVMLTQVQTMLGSIDEQHVIALLKALTDADIGVLMQTCAQ 270
                        250       260       270
                 ....*....|....*....|....*....|....
gi 944375488 241 IATLGPDFDQ-LHAELEgLLHRIAMAQLLPASVQ 273
Cdd:PRK14949 271 VLAFGADAQEvLRSLLE-LLHQITLTQFAPAAAQ 303
PRK14969 PRK14969
DNA polymerase III subunits gamma and tau; Provisional
1-272 8.83e-143

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237873 [Multi-domain]  Cd Length: 527  Bit Score: 411.06  E-value: 8.83e-143
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944375488   1 ALDQGRLHHAYLLSGTRGVGKTTIARILAKSLNCEQGISSHPCGVCDTCREIDQGNFVDLLEIDAASRTKVEDTRELLDN 80
Cdd:PRK14969  31 ALEQQRLHHAYLFTGTRGVGKTTLARILAKSLNCETGVTATPCGVCSACLEIDSGRFVDLIEVDAASNTQVDAMRELLDN 110
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944375488  81 VQYRPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPPYVKFLLATTDPQKLPITILSRCLQFHLKSLDQTQIAKQLEWV 160
Cdd:PRK14969 111 AQYAPTRGRFKVYIIDEVHMLSKSAFNAMLKTLEEPPEHVKFILATTDPQKIPVTVLSRCLQFNLKQMPPPLIVSHLQHI 190
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944375488 161 LDQEGQPFEPRALLALAKAADGSMRDALSLTDQALAHGNGSVRLESVLAMLGTLDHRHLHQLLEAILRQDAPATM--AKI 238
Cdd:PRK14969 191 LEQENIPFDATALQLLARAAAGSMRDALSLLDQAIAYGGGTVNESEVRAMLGAIDQDYLFALLEALLAQDGAALLaiADA 270
                        250       260       270
                 ....*....|....*....|....*....|....
gi 944375488 239 TEIATLgpDFDQLHAELEGLLHRIAMAQLLPASV 272
Cdd:PRK14969 271 MEERSL--SFDAALQDLAALLHRLAIAQTVPDSI 302
dnaX_nterm TIGR02397
DNA polymerase III, subunit gamma and tau; This model represents the well-conserved first ~ ...
1-272 3.07e-136

DNA polymerase III, subunit gamma and tau; This model represents the well-conserved first ~ 365 amino acids of the translation of the dnaX gene. The full-length product of the dnaX gene in the model bacterium E. coli is the DNA polymerase III tau subunit. A translational frameshift leads to early termination and a truncated protein subunit gamma, about 1/3 shorter than tau and present in roughly equal amounts. This frameshift mechanism is not necessarily universal for species with DNA polymerase III but appears conserved in the exterme thermophile Thermus thermophilis. [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 274111 [Multi-domain]  Cd Length: 355  Bit Score: 388.46  E-value: 3.07e-136
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944375488    1 ALDQGRLHHAYLLSGTRGVGKTTIARILAKSLNCEQGISSHPCGVCDTCREIDQGNFVDLLEIDAASRTKVEDTRELLDN 80
Cdd:TIGR02397  29 AIKNGRIAHAYLFSGPRGTGKTSIARIFAKALNCQNGPDGEPCNECESCKEINSGSSLDVIEIDAASNNGVDDIREILDN 108
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944375488   81 VQYRPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPPYVKFLLATTDPQKLPITILSRCLQFHLKSLDQTQIAKQLEWV 160
Cdd:TIGR02397 109 VKYAPSSGKYKVYIIDEVHMLSKSAFNALLKTLEEPPEHVVFILATTEPHKIPATILSRCQRFDFKRIPLEDIVERLKKI 188
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944375488  161 LDQEGQPFEPRALLALAKAADGSMRDALSLTDQALAHGNGSVRLESVLAMLGTLDHRHLHQLLEAILRQDAPATMAKITE 240
Cdd:TIGR02397 189 LDKEGIKIEDEALELIARAADGSLRDALSLLDQLISFGNGKITYEDVNELLGLVDDEKLIELLEAILNKDTAEALKILDE 268
                         250       260       270
                  ....*....|....*....|....*....|..
gi 944375488  241 IATLGPDFDQLHAELEGLLHRIAMAQLLPASV 272
Cdd:TIGR02397 269 ILESGVDPEKFLEDLIEILRDLLLIKKTPSNL 300
DnaX COG2812
DNA polymerase III, gamma/tau subunits [Replication, recombination and repair];
1-271 3.05e-131

DNA polymerase III, gamma/tau subunits [Replication, recombination and repair];


Pssm-ID: 442061 [Multi-domain]  Cd Length: 340  Bit Score: 374.91  E-value: 3.05e-131
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944375488   1 ALDQGRLHHAYLLSGTRGVGKTTIARILAKSLNCEQGISSHPCGVCDTCREIDQGNFVDLLEIDA-ASRTKVEDTRELLD 79
Cdd:COG2812   25 ALASGRLAHAYLFTGPRGVGKTTLARILAKALNCENGPTGEPCGECESCRAIAAGSHPDVIEIDAeASNIGVDDIRELIE 104
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944375488  80 NVQYRPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPPYVKFLLATTDPQKLPITILSRCLQFHLKSLDQTQIAKQLEW 159
Cdd:COG2812  105 KVSYAPVEGRYKVYIIDEAHMLTTEAFNALLKTLEEPPPHVVFILATTEPQKLLPTILSRCQRFDFRRLPPEEIAEHLAK 184
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944375488 160 VLDQEGQPFEPRALLALAKAADGSMRDALSLTDQALAHGNGSVRlesvlamlgtldhRHLHQLLEAILRQDAPATMAKIT 239
Cdd:COG2812  185 IAEREGIEIEPEALALIARAADGSMRDALSLLDQAIAFGLLDRR-------------ELLLDLLEALLAGDVAALLALAE 251
                        250       260       270
                 ....*....|....*....|....*....|..
gi 944375488 240 EIATLGPDFDQLHAELEGLLHRIAMAQLLPAS 271
Cdd:COG2812  252 ELAKRGRDLKRFLDDLLSLLRDLLLLKLGPDA 283
PRK08691 PRK08691
DNA polymerase III subunits gamma and tau; Validated
1-272 4.88e-127

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236333 [Multi-domain]  Cd Length: 709  Bit Score: 377.13  E-value: 4.88e-127
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944375488   1 ALDQGRLHHAYLLSGTRGVGKTTIARILAKSLNCEQGISSHPCGVCDTCREIDQGNFVDLLEIDAASRTKVEDTRELLDN 80
Cdd:PRK08691  31 ALDEGRLHHAYLLTGTRGVGKTTIARILAKSLNCENAQHGEPCGVCQSCTQIDAGRYVDLLEIDAASNTGIDNIREVLEN 110
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944375488  81 VQYRPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPPYVKFLLATTDPQKLPITILSRCLQFHLKSLDQTQIAKQLEWV 160
Cdd:PRK08691 111 AQYAPTAGKYKVYIIDEVHMLSKSAFNAMLKTLEEPPEHVKFILATTDPHKVPVTVLSRCLQFVLRNMTAQQVADHLAHV 190
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944375488 161 LDQEGQPFEPRALLALAKAADGSMRDALSLTDQALAHGNGSVRLESVLAMLGTLDHRHLHQLLEAILRQDAPATMAKITE 240
Cdd:PRK08691 191 LDSEKIAYEPPALQLLGRAAAGSMRDALSLLDQAIALGSGKVAENDVRQMIGAVDKQYLYELLTGIINQDGAALLAKAQE 270
                        250       260       270
                 ....*....|....*....|....*....|..
gi 944375488 241 IATLGPDFDQLHAELEGLLHRIAMAQLLPASV 272
Cdd:PRK08691 271 MAACAVGFDNALGELAILLQQLALIQAVPSAL 302
PRK12323 PRK12323
DNA polymerase III subunit gamma/tau;
1-273 4.87e-125

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237057 [Multi-domain]  Cd Length: 700  Bit Score: 371.52  E-value: 4.87e-125
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944375488   1 ALDQGRLHHAYLLSGTRGVGKTTIARILAKSLNC-----EQGISSHPCGVCDTCREIDQGNFVDLLEIDAASRTKVEDTR 75
Cdd:PRK12323  31 ALEQQRLHHAYLFTGTRGVGKTTLSRILAKSLNCtgadgEGGITAQPCGQCRACTEIDAGRFVDYIEMDAASNRGVDEMA 110
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944375488  76 ELLDNVQYRPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPPYVKFLLATTDPQKLPITILSRCLQFHLKSLDQTQIAK 155
Cdd:PRK12323 111 QLLDKAVYAPTAGRFKVYMIDEVHMLTNHAFNAMLKTLEEPPEHVKFILATTDPQKIPVTVLSRCLQFNLKQMPPGHIVS 190
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944375488 156 QLEWVLDQEGQPFEPRALLALAKAADGSMRDALSLTDQALAHGNGSVRLESVLAMLGTLDHRHLHQLLEAILRQDAPATM 235
Cdd:PRK12323 191 HLDAILGEEGIAHEVNALRLLAQAAQGSMRDALSLTDQAIAYSAGNVSEEAVRGMLGAIDQSYLVRLLDALAAEDGAALL 270
                        250       260       270
                 ....*....|....*....|....*....|....*...
gi 944375488 236 AKITEIATLGPDFDQLHAELEGLLHRIAMAQLLPASVQ 273
Cdd:PRK12323 271 AIADEMAGRSLSFAGALQDLASLLQKIALAQVVPAAVQ 308
PRK14961 PRK14961
DNA polymerase III subunits gamma and tau; Provisional
5-269 4.08e-122

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 184925 [Multi-domain]  Cd Length: 363  Bit Score: 352.96  E-value: 4.08e-122
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944375488   5 GRLHHAYLLSGTRGVGKTTIARILAKSLNCEQGISSHPCGVCDTCREIDQGNFVDLLEIDAASRTKVEDTRELLDNVQYR 84
Cdd:PRK14961  35 GRIHHAWLLSGTRGVGKTTIARLLAKSLNCQNGITSNPCRKCIICKEIEKGLCLDLIEIDAASRTKVEEMREILDNIYYS 114
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944375488  85 PARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPPYVKFLLATTDPQKLPITILSRCLQFHLKSLDQTQIAKQLEWVLDQE 164
Cdd:PRK14961 115 PSKSRFKVYLIDEVHMLSRHSFNALLKTLEEPPQHIKFILATTDVEKIPKTILSRCLQFKLKIISEEKIFNFLKYILIKE 194
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944375488 165 GQPFEPRALLALAKAADGSMRDALSLTDQALAHGNGSVRLESVLAMLGTLDHRHLHQLLEAILRQDAPATMAKITEIATL 244
Cdd:PRK14961 195 SIDTDEYALKLIAYHAHGSMRDALNLLEHAINLGKGNINIKNVTDMLGLLNEKQSFLLTDALLKKDSKKTMLLLNKISSI 274
                        250       260
                 ....*....|....*....|....*
gi 944375488 245 GPDFDQLHAELEGLLHRIAMAQLLP 269
Cdd:PRK14961 275 GIEWENILIEMLRFLHHISMSQSFP 299
PRK14951 PRK14951
DNA polymerase III subunits gamma and tau; Provisional
1-272 4.93e-119

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237865 [Multi-domain]  Cd Length: 618  Bit Score: 353.64  E-value: 4.93e-119
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944375488   1 ALDQGRLHHAYLLSGTRGVGKTTIARILAKSLNC-----EQGISSHPCGVCDTCREIDQGNFVDLLEIDAASRTKVEDTR 75
Cdd:PRK14951  31 ALTQQRLHHAYLFTGTRGVGKTTVSRILAKSLNCqgpdgQGGITATPCGVCQACRDIDSGRFVDYTELDAASNRGVDEVQ 110
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944375488  76 ELLDNVQYRPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPPYVKFLLATTDPQKLPITILSRCLQFHLKSLDQTQIAK 155
Cdd:PRK14951 111 QLLEQAVYKPVQGRFKVFMIDEVHMLTNTAFNAMLKTLEEPPEYLKFVLATTDPQKVPVTVLSRCLQFNLRPMAPETVLE 190
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944375488 156 QLEWVLDQEGQPFEPRALLALAKAADGSMRDALSLTDQALAHGNGSVRLESVLAMLGTLDHRHLHQLLEAILRQDAPATM 235
Cdd:PRK14951 191 HLTQVLAAENVPAEPQALRLLARAARGSMRDALSLTDQAIAFGSGQLQEAAVRQMLGSVDRSHVFRLIDALAQGDGRTVV 270
                        250       260       270
                 ....*....|....*....|....*....|....*..
gi 944375488 236 AKITEIATLGPDFDQLHAELEGLLHRIAMAQLLPASV 272
Cdd:PRK14951 271 ETADELRLNGLSAASTLEEMAAVLQRMAVLQAVPQAA 307
PRK07003 PRK07003
DNA polymerase III subunit gamma/tau;
1-272 1.44e-118

DNA polymerase III subunit gamma/tau;


Pssm-ID: 235906 [Multi-domain]  Cd Length: 830  Bit Score: 358.39  E-value: 1.44e-118
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944375488   1 ALDQGRLHHAYLLSGTRGVGKTTIARILAKSLNCEQGISSHPCGVCDTCREIDQGNFVDLLEIDAASRTKVEDTRELLDN 80
Cdd:PRK07003  31 ALDGGRLHHAYLFTGTRGVGKTTLSRIFAKALNCETGVTSQPCGVCRACREIDEGRFVDYVEMDAASNRGVDEMAALLER 110
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944375488  81 VQYRPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPPYVKFLLATTDPQKLPITILSRCLQFHLKSLDQTQIAKQLEWV 160
Cdd:PRK07003 111 AVYAPVDARFKVYMIDEVHMLTNHAFNAMLKTLEEPPPHVKFILATTDPQKIPVTVLSRCLQFNLKQMPAGHIVSHLERI 190
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944375488 161 LDQEGQPFEPRALLALAKAADGSMRDALSLTDQALAHGNGSVRLESVLAMLGTLDHRHLHQLLEAILRQDAPATMAKITE 240
Cdd:PRK07003 191 LGEERIAFEPQALRLLARAAQGSMRDALSLTDQAIAYSANEVTETAVSGMLGALDQTYMVRLLDALAAGDGPEILAVADE 270
                        250       260       270
                 ....*....|....*....|....*....|..
gi 944375488 241 IATLGPDFDQLHAELEGLLHRIAMAQLLPASV 272
Cdd:PRK07003 271 MALRSLSFSTALQDLASLLHRIAWAQFAPASV 302
PRK05563 PRK05563
DNA polymerase III subunits gamma and tau; Validated
1-241 1.32e-112

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 235505 [Multi-domain]  Cd Length: 559  Bit Score: 335.30  E-value: 1.32e-112
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944375488   1 ALDQGRLHHAYLLSGTRGVGKTTIARILAKSLNCEQGISSHPCGVCDTCREIDQGNFVDLLEIDAASRTKVEDTRELLDN 80
Cdd:PRK05563  31 AIKQGKISHAYLFSGPRGTGKTSAAKIFAKAVNCLNPPDGEPCNECEICKAITNGSLMDVIEIDAASNNGVDEIRDIRDK 110
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944375488  81 VQYRPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPPYVKFLLATTDPQKLPITILSRCLQFHLKSLDQTQIAKQLEWV 160
Cdd:PRK05563 111 VKYAPSEAKYKVYIIDEVHMLSTGAFNALLKTLEEPPAHVIFILATTEPHKIPATILSRCQRFDFKRISVEDIVERLKYI 190
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944375488 161 LDQEGQPFEPRALLALAKAADGSMRDALSLTDQALAHGNGSVRLESVLAMLGTLDHRHLHQLLEAILRQDAPATMAKITE 240
Cdd:PRK05563 191 LDKEGIEYEDEALRLIARAAEGGMRDALSILDQAISFGDGKVTYEDALEVTGSVSQEALDDLVDAIVEGDVAKALKILEE 270

                 .
gi 944375488 241 I 241
Cdd:PRK05563 271 L 271
PRK14960 PRK14960
DNA polymerase III subunit gamma/tau;
1-269 2.07e-112

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237868 [Multi-domain]  Cd Length: 702  Bit Score: 339.33  E-value: 2.07e-112
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944375488   1 ALDQGRLHHAYLLSGTRGVGKTTIARILAKSLNCEQGISSHPCGVCDTCREIDQGNFVDLLEIDAASRTKVEDTRELLDN 80
Cdd:PRK14960  30 ALERGRLHHAYLFTGTRGVGKTTIARILAKCLNCETGVTSTPCEVCATCKAVNEGRFIDLIEIDAASRTKVEDTRELLDN 109
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944375488  81 VQYRPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPPYVKFLLATTDPQKLPITILSRCLQFHLKSLDQTQIAKQLEWV 160
Cdd:PRK14960 110 VPYAPTQGRFKVYLIDEVHMLSTHSFNALLKTLEEPPEHVKFLFATTDPQKLPITVISRCLQFTLRPLAVDEITKHLGAI 189
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944375488 161 LDQEGQPFEPRALLALAKAADGSMRDALSLTDQALAHGNGSVRLESVLAMLGTLDHRHLHQLLEAILRQDAPATMAKITE 240
Cdd:PRK14960 190 LEKEQIAADQDAIWQIAESAQGSLRDALSLTDQAIAYGQGAVHHQDVKEMLGLIDRTIIYDLILAVHQNQREKVSQLLLQ 269
                        250       260
                 ....*....|....*....|....*....
gi 944375488 241 IATLGPDFDQLHAELEGLLHRIAMAQLLP 269
Cdd:PRK14960 270 FRYQALDVSLVLDQLISTLHELALLQYLP 298
PRK14965 PRK14965
DNA polymerase III subunits gamma and tau; Provisional
1-269 1.52e-105

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237871 [Multi-domain]  Cd Length: 576  Bit Score: 317.84  E-value: 1.52e-105
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944375488   1 ALDQGRLHHAYLLSGTRGVGKTTIARILAKSLNCEQGISSHPCGVCDTCREIDQGNFVDLLEIDAASRTKVEDTRELLDN 80
Cdd:PRK14965  31 AIDTGRVAHAFLFTGARGVGKTSTARILAKALNCEQGLTAEPCNVCPPCVEITEGRSVDVFEIDGASNTGVDDIRELREN 110
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944375488  81 VQYRPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPPYVKFLLATTDPQKLPITILSRCLQFHLKSLDQTQIAKQLEWV 160
Cdd:PRK14965 111 VKYLPSRSRYKIFIIDEVHMLSTNAFNALLKTLEEPPPHVKFIFATTEPHKVPITILSRCQRFDFRRIPLQKIVDRLRYI 190
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944375488 161 LDQEGQPFEPRALLALAKAADGSMRDALSLTDQALAHGNGSVRLESVLAMLGTLDHRHLHQLLEAILRQDAPATMAKITE 240
Cdd:PRK14965 191 ADQEGISISDAALALVARKGDGSMRDSLSTLDQVLAFCGDAVGDDDVAELLGVVDRRLLLDISAAVFGRDTRALLEIVER 270
                        250       260
                 ....*....|....*....|....*....
gi 944375488 241 IATLGPDFDQLHAELEGLLHRIAMAQLLP 269
Cdd:PRK14965 271 VDEFGYNMRQFCQELIDHLRNLVVLRAVG 299
PRK14958 PRK14958
DNA polymerase III subunits gamma and tau; Provisional
1-272 3.02e-102

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 184922 [Multi-domain]  Cd Length: 509  Bit Score: 307.43  E-value: 3.02e-102
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944375488   1 ALDQGRLHHAYLLSGTRGVGKTTIARILAKSLNCEQGISSHPCGVCDTCREIDQGNFVDLLEIDAASRTKVEDTRELLDN 80
Cdd:PRK14958  31 ALDQQYLHHAYLFTGTRGVGKTTISRILAKCLNCEKGVSANPCNDCENCREIDEGRFPDLFEVDAASRTKVEDTRELLDN 110
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944375488  81 VQYRPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPPYVKFLLATTDPQKLPITILSRCLQFHLKSLDQTQIAKQLEWV 160
Cdd:PRK14958 111 IPYAPTKGRFKVYLIDEVHMLSGHSFNALLKTLEEPPSHVKFILATTDHHKLPVTVLSRCLQFHLAQLPPLQIAAHCQHL 190
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944375488 161 LDQEGQPFEPRALLALAKAADGSMRDALSLTDQALAHGNGSVRLESVLAMLGTLDHRHLHQLLEAILRQDAPATMAKITE 240
Cdd:PRK14958 191 LKEENVEFENAALDLLARAANGSVRDALSLLDQSIAYGNGKVLIADVKTMLGTIEPLLLFDILEALAAKAGDRLLGCVTR 270
                        250       260       270
                 ....*....|....*....|....*....|..
gi 944375488 241 IATLGPDFDQLHAELEGLLHRIAMAQLLPASV 272
Cdd:PRK14958 271 LVEQGVDFSNALADLLSLLHQIAIIQTVPEAL 302
PRK09111 PRK09111
DNA polymerase III subunits gamma and tau; Validated
1-273 3.00e-100

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236382 [Multi-domain]  Cd Length: 598  Bit Score: 304.90  E-value: 3.00e-100
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944375488   1 ALDQGRLHHAYLLSGTRGVGKTTIARILAKSLNCE-----QGISSHPCGVCDTCREIDQGNFVDLLEIDAASRTKVEDTR 75
Cdd:PRK09111  39 AFETGRIAQAFMLTGVRGVGKTTTARILARALNYEgpdgdGGPTIDLCGVGEHCQAIMEGRHVDVLEMDAASHTGVDDIR 118
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944375488  76 ELLDNVQYRPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPPYVKFLLATTDPQKLPITILSRCLQFHLKSLDQTQIAK 155
Cdd:PRK09111 119 EIIESVRYRPVSARYKVYIIDEVHMLSTAAFNALLKTLEEPPPHVKFIFATTEIRKVPVTVLSRCQRFDLRRIEADVLAA 198
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944375488 156 QLEWVLDQEGQPFEPRALLALAKAADGSMRDALSLTDQALAHGNGSVRLESVLAMLGTLDHRHLHQLLEAILRQDAPATM 235
Cdd:PRK09111 199 HLSRIAAKEGVEVEDEALALIARAAEGSVRDGLSLLDQAIAHGAGEVTAEAVRDMLGLADRARVIDLFEALMRGDVAAAL 278
                        250       260       270
                 ....*....|....*....|....*....|....*...
gi 944375488 236 AKITEIATLGPDFDQLHAELEGLLHRIAMAQLLPASVQ 273
Cdd:PRK09111 279 AEFRAQYDAGADPVVVLTDLAEFTHLVTRLKIVPDAAE 316
PRK08451 PRK08451
DNA polymerase III subunits gamma and tau; Validated
1-240 2.18e-97

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236267 [Multi-domain]  Cd Length: 535  Bit Score: 295.40  E-value: 2.18e-97
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944375488   1 ALDQGRLHHAYLLSGTRGVGKTTIARILAKSLNCEQGISSHPCGVCDTCREIDQGNFVDLLEIDAASRTKVEDTRELLDN 80
Cdd:PRK08451  29 ALDNNRLAHAYLFSGLRGSGKTSSARIFARALVCEQGPSSTPCDTCIQCQSALENRHIDIIEMDAASNRGIDDIRELIEQ 108
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944375488  81 VQYRPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPPYVKFLLATTDPQKLPITILSRCLQFHLKSLDQTQIAKQLEWV 160
Cdd:PRK08451 109 TKYKPSMARFKIFIIDEVHMLTKEAFNALLKTLEEPPSYVKFILATTDPLKLPATILSRTQHFRFKQIPQNSIISHLKTI 188
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944375488 161 LDQEGQPFEPRALLALAKAADGSMRDALSLTDQALAHGNGSVRLESVLAMLGTLDHRHLHQLLEAILRQDAPATMAKITE 240
Cdd:PRK08451 189 LEKEGVSYEPEALEILARSGNGSLRDTLTLLDQAIIYCKNAITESKVADMLGLLDPSKLEDFFQAILNQDKEKLFELLKE 268
PRK14957 PRK14957
DNA polymerase III subunits gamma and tau; Provisional
1-242 5.12e-96

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 184921 [Multi-domain]  Cd Length: 546  Bit Score: 292.37  E-value: 5.12e-96
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944375488   1 ALDQGRLHHAYLLSGTRGVGKTTIARILAKSLNCEQGISSHPCGVCDTCREIDQGNFVDLLEIDAASRTKVEDTRELLDN 80
Cdd:PRK14957  31 ALETQKVHHAYLFTGTRGVGKTTLGRLLAKCLNCKTGVTAEPCNKCENCVAINNNSFIDLIEIDAASRTGVEETKEILDN 110
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944375488  81 VQYRPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPPYVKFLLATTDPQKLPITILSRCLQFHLKSLDQTQIAKQLEWV 160
Cdd:PRK14957 111 IQYMPSQGRYKVYLIDEVHMLSKQSFNALLKTLEEPPEYVKFILATTDYHKIPVTILSRCIQLHLKHISQADIKDQLKII 190
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944375488 161 LDQEGQPFEPRALLALAKAADGSMRDALSLTDQALAHGNGSVRLESVLAMLGTLDHRHLHQLLEAILRQDAPATMAKITE 240
Cdd:PRK14957 191 LAKENINSDEQSLEYIAYHAKGSLRDALSLLDQAISFCGGELKQAQIKQMLGIIDSEEVYSIINAIIDNDPKAILPAIKN 270

                 ..
gi 944375488 241 IA 242
Cdd:PRK14957 271 LA 272
PRK14953 PRK14953
DNA polymerase III subunits gamma and tau; Provisional
1-262 3.62e-94

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237867 [Multi-domain]  Cd Length: 486  Bit Score: 285.95  E-value: 3.62e-94
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944375488   1 ALDQGRLHHAYLLSGTRGVGKTTIARILAKSLNCEQGISSHPCGVCDTCREIDQGNFVDLLEIDAASRTKVEDTRELLDN 80
Cdd:PRK14953  31 AVKLQRVSHAYIFAGPRGTGKTTIARILAKVLNCLNPQEGEPCGKCENCVEIDKGSFPDLIEIDAASNRGIDDIRALRDA 110
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944375488  81 VQYRPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPPYVKFLLATTDPQKLPITILSRCLQFHLKSLDQTQIAKQLEWV 160
Cdd:PRK14953 111 VSYTPIKGKYKVYIIDEAHMLTKEAFNALLKTLEEPPPRTIFILCTTEYDKIPPTILSRCQRFIFSKPTKEQIKEYLKRI 190
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944375488 161 LDQEGQPFEPRALLALAKAADGSMRDALSLTDQALAHGNGSVRLESVLAMLGTLDHRHLHQLLEAILRQDAPATMAKITE 240
Cdd:PRK14953 191 CNEEKIEYEEKALDLLAQASEGGMRDAASLLDQASTYGEGKVTIKVVEEFLGIVSQESVRKFLNLLLESDVDEAIKFLRT 270
                        250       260
                 ....*....|....*....|..
gi 944375488 241 IATLGPDFDQLHAELEGLLHRI 262
Cdd:PRK14953 271 LEEKGYNLNKFWKQLEEEIRNI 292
PRK14950 PRK14950
DNA polymerase III subunits gamma and tau; Provisional
1-255 8.65e-89

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237864 [Multi-domain]  Cd Length: 585  Bit Score: 274.76  E-value: 8.65e-89
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944375488   1 ALDQGRLHHAYLLSGTRGVGKTTIARILAKSLNCEQGI-SSHPCGVCDTCREIDQGNFVDLLEIDAASRTKVEDTRELLD 79
Cdd:PRK14950  31 AIAEGRVAHAYLFTGPRGVGKTSTARILAKAVNCTTNDpKGRPCGTCEMCRAIAEGSAVDVIEMDAASHTSVDDAREIIE 110
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944375488  80 NVQYRPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPPYVKFLLATTDPQKLPITILSRCLQFHLKSLDQTQIAKQLEW 159
Cdd:PRK14950 111 RVQFRPALARYKVYIIDEVHMLSTAAFNALLKTLEEPPPHAIFILATTEVHKVPATILSRCQRFDFHRHSVADMAAHLRK 190
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944375488 160 VLDQEGQPFEPRALLALAKAADGSMRDALSLTDQALAHGNGSVRLESVLAMLGTLDHRHLHQLLEAILRQDAPATMAKIT 239
Cdd:PRK14950 191 IAAAEGINLEPGALEAIARAATGSMRDAENLLQQLATTYGGEISLSQVQSLLGISGDEEVKALAEALLAKDLKAALRTLN 270
                        250
                 ....*....|....*.
gi 944375488 240 EIATLGPDFDQLHAEL 255
Cdd:PRK14950 271 AVAADGADLRQFTRDL 286
PRK14964 PRK14964
DNA polymerase III subunits gamma and tau; Provisional
5-241 1.27e-80

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237870 [Multi-domain]  Cd Length: 491  Bit Score: 251.24  E-value: 1.27e-80
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944375488   5 GRLHHAYLLSGTRGVGKTTIARILAKSLNCEQGISSHPCGVCDTCREIDQGNFVDLLEIDAASRTKVEDTRELLDNVQYR 84
Cdd:PRK14964  32 NKIPQSILLVGASGVGKTTCARIISLCLNCSNGPTSDPCGTCHNCISIKNSNHPDVIEIDAASNTSVDDIKVILENSCYL 111
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944375488  85 PARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPPYVKFLLATTDPQKLPITILSRCLQFHLKSLDQTQIAKQLEWVLDQE 164
Cdd:PRK14964 112 PISSKFKVYIIDEVHMLSNSAFNALLKTLEEPAPHVKFILATTEVKKIPVTIISRCQRFDLQKIPTDKLVEHLVDIAKKE 191
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 944375488 165 GQPFEPRALLALAKAADGSMRDALSLTDQALAHGNGSVRLESVLAMLGTLDHRHLHQLLEAILRQDAPATMAKITEI 241
Cdd:PRK14964 192 NIEHDEESLKLIAENSSGSMRNALFLLEQAAIYSNNKISEKSVRDLLGCVDKHILEDLVEAILLGDAQSALNVFREL 268
PRK14959 PRK14959
DNA polymerase III subunits gamma and tau; Provisional
1-247 3.85e-80

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 184923 [Multi-domain]  Cd Length: 624  Bit Score: 253.45  E-value: 3.85e-80
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944375488   1 ALDQGRLHHAYLLSGTRGVGKTTIARILAKSLNCEQGISSHPCGVCDTCREIDQGNFVDLLEIDAASRTKVEDTRELLDN 80
Cdd:PRK14959  31 AAQENRVAPAYLFSGTRGVGKTTIARIFAKALNCETAPTGEPCNTCEQCRKVTQGMHVDVVEIDGASNRGIDDAKRLKEA 110
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944375488  81 VQYRPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPPYVKFLLATTDPQKLPITILSRCLQFHLKSLDQTQIAKQLEWV 160
Cdd:PRK14959 111 IGYAPMEGRYKVFIIDEAHMLTREAFNALLKTLEEPPARVTFVLATTEPHKFPVTIVSRCQHFTFTRLSEAGLEAHLTKV 190
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944375488 161 LDQEGQPFEPRALLALAKAADGSMRDALSLTDQALAHGNGSVRLESVLAMLGTLDHRHLHQLLEAILRQDAPATMAKITE 240
Cdd:PRK14959 191 LGREGVDYDPAAVRLIARRAAGSVRDSMSLLGQVLALGESRLTIDGARGVLGLAGQELFLRLMEALAAQDCLGVANVVRE 270

                 ....*..
gi 944375488 241 IATLGPD 247
Cdd:PRK14959 271 LLDRGVD 277
PRK06647 PRK06647
DNA polymerase III subunits gamma and tau; Validated
1-231 4.86e-80

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 235845 [Multi-domain]  Cd Length: 563  Bit Score: 251.61  E-value: 4.86e-80
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944375488   1 ALDQGRLHHAYLLSGTRGVGKTTIARILAKSLNCEQGISSHPCGVCDTCREIDQGNFVDLLEIDAASRTKVEDTRELLDN 80
Cdd:PRK06647  31 SIESNKIANAYIFSGPRGVGKTSSARAFARCLNCVNGPTPMPCGECSSCKSIDNDNSLDVIEIDGASNTSVQDVRQIKEE 110
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944375488  81 VQYRPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPPYVKFLLATTDPQKLPITILSRCLQFHLKSLDQTQIAKQLEWV 160
Cdd:PRK06647 111 IMFPPASSRYRVYIIDEVHMLSNSAFNALLKTIEEPPPYIVFIFATTEVHKLPATIKSRCQHFNFRLLSLEKIYNMLKKV 190
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 944375488 161 LDQEGQPFEPRALLALAKAADGSMRDALSLTDQALAHGNGSVRLESVLAMLGTLDHRHLHQLLEAILRQDA 231
Cdd:PRK06647 191 CLEDQIKYEDEALKWIAYKSTGSVRDAYTLFDQVVSFSDSDITLEQIRSKMGLTGDEFLEKLASSILNEDA 261
PRK14962 PRK14962
DNA polymerase III subunits gamma and tau; Provisional
1-251 3.74e-77

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237869 [Multi-domain]  Cd Length: 472  Bit Score: 241.59  E-value: 3.74e-77
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944375488   1 ALDQGRLHHAYLLSGTRGVGKTTIARILAKSLNCEQGISSHPCGVCDTCREIDQGNFVDLLEIDAASRTKVEDTRELLDN 80
Cdd:PRK14962  29 ALKKNSISHAYIFAGPRGTGKTTVARILAKSLNCENRKGVEPCNECRACRSIDEGTFMDVIELDAASNRGIDEIRKIRDA 108
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944375488  81 VQYRPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPPYVKFLLATTDPQKLPITILSRCLQFHLKSLDQTQIAKQLEWV 160
Cdd:PRK14962 109 VGYRPMEGKYKVYIIDEVHMLTKEAFNALLKTLEEPPSHVVFVLATTNLEKVPPTIISRCQVIEFRNISDELIIKRLQEV 188
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944375488 161 LDQEGQPFEPRALLALAKAADGSMRDALSLTDQALAHGNGSVRLESVLAMLGTLDHRHLHQLLEAILRQDAPATMAKITE 240
Cdd:PRK14962 189 AEAEGIEIDREALSFIAKRASGGLRDALTMLEQVWKFSEGKITLETVHEALGLIPIEVVRDYINAIFNGDVKRVFTVLDD 268
                        250
                 ....*....|.
gi 944375488 241 IATLGPDFDQL 251
Cdd:PRK14962 269 VYYSGKDYEVL 279
PRK06305 PRK06305
DNA polymerase III subunits gamma and tau; Validated
1-247 3.10e-76

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 180523 [Multi-domain]  Cd Length: 451  Bit Score: 238.52  E-value: 3.10e-76
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944375488   1 ALDQGRLHHAYLLSGTRGVGKTTIARILAKSLNCEQGISSH-PCGVCDTCREIDQGNFVDLLEIDAASRTKVEDTRELLD 79
Cdd:PRK06305  32 ALRFNRAAHAYLFSGIRGTGKTTLARIFAKALNCQNPTEDQePCNQCASCKEISSGTSLDVLEIDGASHRGIEDIRQINE 111
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944375488  80 NVQYRPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPPYVKFLLATTDPQKLPITILSRCLQFHLKSLDQTQIAKQLEW 159
Cdd:PRK06305 112 TVLFTPSKSRYKIYIIDEVHMLTKEAFNSLLKTLEEPPQHVKFFLATTEIHKIPGTILSRCQKMHLKRIPEETIIDKLAL 191
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944375488 160 VLDQEGQPFEPRALLALAKAADGSMRDALSLTDQALAHGNGSVRLESVLAMLGTLDHRHLHQLLEAILRQDAPATMAKIT 239
Cdd:PRK06305 192 IAKQEGIETSREALLPIARAAQGSLRDAESLYDYVVGLFPKSLDPDSVAKALGLLSQDSLYTLDEAITTQNYAQALEPVT 271

                 ....*...
gi 944375488 240 EIATLGPD 247
Cdd:PRK06305 272 DAMNSGVA 279
PRK14948 PRK14948
DNA polymerase III subunit gamma/tau;
1-230 5.07e-76

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237862 [Multi-domain]  Cd Length: 620  Bit Score: 242.56  E-value: 5.07e-76
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944375488   1 ALDQGRLHHAYLLSGTRGVGKTTIARILAKSLNC--EQGISSHPCGVCDTCREIDQGNFVDLLEIDAASRTKVEDTRELL 78
Cdd:PRK14948  31 ALISNRIAPAYLFTGPRGTGKTSSARILAKSLNClnSDKPTPEPCGKCELCRAIAAGNALDVIEIDAASNTGVDNIRELI 110
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944375488  79 DNVQYRPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPPYVKFLLATTDPQK-LPiTILSRCLQFHLKSLDQTQIAKQL 157
Cdd:PRK14948 111 ERAQFAPVQARWKVYVIDECHMLSTAAFNALLKTLEEPPPRVVFVLATTDPQRvLP-TIISRCQRFDFRRIPLEAMVQHL 189
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 944375488 158 EWVLDQEGQPFEPRALLALAKAADGSMRDALSLTDQaLAHGNGSVRLESVLAMLGTLDHRHLHQLLEAILRQD 230
Cdd:PRK14948 190 SEIAEKESIEIEPEALTLVAQRSQGGLRDAESLLDQ-LSLLPGPITPEAVWDLLGAVPEQDLLNLLKALASND 261
PRK14955 PRK14955
DNA polymerase III subunits gamma and tau; Provisional
1-235 2.31e-73

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 184919 [Multi-domain]  Cd Length: 397  Bit Score: 229.78  E-value: 2.31e-73
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944375488   1 ALDQGRLHHAYLLSGTRGVGKTTIARILAKSLNCEQGIS--------SHPCGVCDTCREIDQGNFVDLLEIDAASRTKVE 72
Cdd:PRK14955  31 SLRMGRVGHGYIFSGLRGVGKTTAARVFAKAVNCQRMIDdadylqevTEPCGECESCRDFDAGTSLNISEFDAASNNSVD 110
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944375488  73 DTRELLDNVQYRPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPPYVKFLLATTDPQKLPITILSRCLQFHLKSLDQTQ 152
Cdd:PRK14955 111 DIRLLRENVRYGPQKGRYRVYIIDEVHMLSIAAFNAFLKTLEEPPPHAIFIFATTELHKIPATIASRCQRFNFKRIPLEE 190
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944375488 153 IAKQLEWVLDQEGQPFEPRALLALAKAADGSMRDALSLTDQALA-----HGNGSVRLESVLAMLGTLDHRHLHQLLEAIL 227
Cdd:PRK14955 191 IQQQLQGICEAEGISVDADALQLIGRKAQGSMRDAQSILDQVIAfsvesEGEGSIRYDKVAELLNYIDDEHFFAVTDAVA 270

                 ....*...
gi 944375488 228 RQDAPATM 235
Cdd:PRK14955 271 DGDAVAML 278
PRK07133 PRK07133
DNA polymerase III subunits gamma and tau; Validated
5-251 2.78e-73

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 235943 [Multi-domain]  Cd Length: 725  Bit Score: 237.79  E-value: 2.78e-73
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944375488   5 GRLHHAYLLSGTRGVGKTTIARILAKSLNCEQgiSSHPCGVCDTCREIDQGNFvDLLEIDAASRTKVEDTRELLDNVQYR 84
Cdd:PRK07133  37 NKISHAYLFSGPRGTGKTSVAKIFANALNCSH--KTDLLEPCQECIENVNNSL-DIIEMDAASNNGVDEIRELIENVKNL 113
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944375488  85 PARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPPYVKFLLATTDPQKLPITILSRCLQFHLKSLDQTQIAKQLEWVLDQE 164
Cdd:PRK07133 114 PTQSKYKIYIIDEVHMLSKSAFNALLKTLEEPPKHVIFILATTEVHKIPLTILSRVQRFNFRRISEDEIVSRLEFILEKE 193
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944375488 165 GQPFEPRALLALAKAADGSMRDALSLTDQALAHGNGSVRLESVLAMLGTLDHRHLHQLLEAILRQDAPATMAKITEIATL 244
Cdd:PRK07133 194 NISYEKNALKLIAKLSSGSLRDALSIAEQVSIFGNNKITLKNVEELFGLVSNENLINLLNLLYSKDIKEVLNILNQIKEQ 273

                 ....*..
gi 944375488 245 GPDFDQL 251
Cdd:PRK07133 274 GIDPELL 280
PRK14963 PRK14963
DNA polymerase III subunits gamma and tau; Provisional
1-231 1.30e-71

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 184927 [Multi-domain]  Cd Length: 504  Bit Score: 228.19  E-value: 1.30e-71
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944375488   1 ALDQGRLHHAYLLSGTRGVGKTTIARILAKSLNCeQGISSHPCGVCDTCREIDQGNFVDLLEIDAASRTKVEDTRELLDN 80
Cdd:PRK14963  29 ALRQGRLGHAYLFSGPRGVGKTTTARLIAMAVNC-SGEDPKPCGECESCLAVRRGAHPDVLEIDAASNNSVEDVRDLREK 107
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944375488  81 VQYRPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPPYVKFLLATTDPQKLPITILSRCLQFHLKSLDQTQIAKQLEWV 160
Cdd:PRK14963 108 VLLAPLRGGRKVYILDEAHMMSKSAFNALLKTLEEPPEHVIFILATTEPEKMPPTILSRTQHFRFRRLTEEEIAGKLRRL 187
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 944375488 161 LDQEGQPFEPRALLALAKAADGSMRDALSLTDQALAHGnGSVRLESVLAMLGTLDHRHLHQLLEAILRQDA 231
Cdd:PRK14963 188 LEAEGREAEPEALQLVARLADGAMRDAESLLERLLALG-TPVTRKQVEEALGLPPQERLRGIAAALAQGDA 257
PRK14971 PRK14971
DNA polymerase III subunit gamma/tau;
1-249 1.74e-71

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237874 [Multi-domain]  Cd Length: 614  Bit Score: 230.43  E-value: 1.74e-71
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944375488   1 ALDQGRLHHAYLLSGTRGVGKTTIARILAKSLNC-EQGISSHPCGVCDTCREIDQGNFVDLLEIDAASRTKVEDTRELLD 79
Cdd:PRK14971  32 AIATNKLAHAYLFCGPRGVGKTTCARIFAKTINCqNLTADGEACNECESCVAFNEQRSYNIHELDAASNNSVDDIRNLIE 111
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944375488  80 NVQYRPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPPYVKFLLATTDPQKLPITILSRCLQFHLKSLDQTQIAKQLEW 159
Cdd:PRK14971 112 QVRIPPQIGKYKIYIIDEVHMLSQAAFNAFLKTLEEPPSYAIFILATTEKHKILPTILSRCQIFDFNRIQVADIVNHLQY 191
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944375488 160 VLDQEGQPFEPRALLALAKAADGSMRDALSLTDQALAHGNGSVRLESVLAMLGTLDHRHLHQLLEAILRQDAPATMAKIT 239
Cdd:PRK14971 192 VASKEGITAEPEALNVIAQKADGGMRDALSIFDQVVSFTGGNITYKSVIENLNILDYDYYFRLTDALLAGKVSDSLLLFD 271
                        250
                 ....*....|
gi 944375488 240 EIatLGPDFD 249
Cdd:PRK14971 272 EI--LNKGFD 279
PRK14956 PRK14956
DNA polymerase III subunits gamma and tau; Provisional
1-212 2.62e-71

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 184920 [Multi-domain]  Cd Length: 484  Bit Score: 226.75  E-value: 2.62e-71
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944375488   1 ALDQGRLHHAYLLSGTRGVGKTTIARILAKSLNCEQGISSHPCGVCDTCREIDQGNFVDLLEIDAASRTKVEDTRELLDN 80
Cdd:PRK14956  33 ALKSGKIGHAYIFFGPRGVGKTTIARILAKRLNCENPIGNEPCNECTSCLEITKGISSDVLEIDAASNRGIENIRELRDN 112
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944375488  81 VQYRPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPPYVKFLLATTDPQKLPITILSRCLQFHLKSLDQTQIAKQLEWV 160
Cdd:PRK14956 113 VKFAPMGGKYKVYIIDEVHMLTDQSFNALLKTLEEPPAHIVFILATTEFHKIPETILSRCQDFIFKKVPLSVLQDYSEKL 192
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|..
gi 944375488 161 LDQEGQPFEPRALLALAKAADGSMRDALSLTDQALAHGNGSVRLESVLAMLG 212
Cdd:PRK14956 193 CKIENVQYDQEGLFWIAKKGDGSVRDMLSFMEQAIVFTDSKLTGVKIRKMIG 244
PRK06645 PRK06645
DNA polymerase III subunits gamma and tau; Validated
5-264 7.24e-71

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 180643 [Multi-domain]  Cd Length: 507  Bit Score: 226.28  E-value: 7.24e-71
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944375488   5 GRLHHAYLLSGTRGVGKTTIARILAKSLNCEQGISSH----PCGVCDTCREIDQGNFVDLLEIDAASRTKVEDTRELLDN 80
Cdd:PRK06645  40 DRLAGGYLLTGIRGVGKTTSARIIAKAVNCSALITENttikTCEQCTNCISFNNHNHPDIIEIDAASKTSVDDIRRIIES 119
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944375488  81 VQYRPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPPYVKFLLATTDPQKLPITILSRCLQFHLKSLDQTQIAKQLEWV 160
Cdd:PRK06645 120 AEYKPLQGKHKIFIIDEVHMLSKGAFNALLKTLEEPPPHIIFIFATTEVQKIPATIISRCQRYDLRRLSFEEIFKLLEYI 199
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944375488 161 LDQEGQPFEPRALLALAKAADGSMRDALSLTDQALAHGNGS---VRLESVLAMLGTLDHRHLHQLLEAILRQDAPATMAK 237
Cdd:PRK06645 200 TKQENLKTDIEALRIIAYKSEGSARDAVSILDQAASMSAKSdniISPQVINQMLGLVDSSVIIEFVEYIIHRETEKAINL 279
                        250       260       270
                 ....*....|....*....|....*....|
gi 944375488 238 ITEIATLGPDFD---QLHAELEGLLHRIAM 264
Cdd:PRK06645 280 INKLYGSSVNLEifiESVSDFIAYLNKVKM 309
PRK14954 PRK14954
DNA polymerase III subunits gamma and tau; Provisional
1-235 4.62e-70

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 184918 [Multi-domain]  Cd Length: 620  Bit Score: 227.13  E-value: 4.62e-70
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944375488   1 ALDQGRLHHAYLLSGTRGVGKTTIARILAKSLNCEQGIS--------SHPCGVCDTCREIDQGNFVDLLEIDAASRTKVE 72
Cdd:PRK14954  31 SLRMDRVGHGYIFSGLRGVGKTTAARVFAKAVNCQRMIDdpvylqevTEPCGECESCRDFDAGTSLNISEFDAASNNSVD 110
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944375488  73 DTRELLDNVQYRPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPPYVKFLLATTDPQKLPITILSRCLQFHLKSLDQTQ 152
Cdd:PRK14954 111 DIRQLRENVRYGPQKGRYRVYIIDEVHMLSTAAFNAFLKTLEEPPPHAIFIFATTELHKIPATIASRCQRFNFKRIPLDE 190
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944375488 153 IAKQLEWVLDQEGQPFEPRALLALAKAADGSMRDALSLTDQALAHGNGS-----VRLESVLAMLGTLDHRHLHQLLEAIL 227
Cdd:PRK14954 191 IQSQLQMICRAEGIQIDADALQLIARKAQGSMRDAQSILDQVIAFSVGSeaekvIAYQGVAELLNYIDDEQFFDVTDAIA 270

                 ....*...
gi 944375488 228 RQDAPATM 235
Cdd:PRK14954 271 ENDAVKML 278
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
1-233 1.28e-69

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 229.49  E-value: 1.28e-69
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944375488   1 ALDQGRLHHAYLLSGTRGVGKTTIARILAKSLNCEQGISSHPCGVCDTCREI---DQGNfVDLLEIDAASRTKVEDTREL 77
Cdd:PRK07764  30 ALDSGRINHAYLFSGPRGCGKTSSARILARSLNCVEGPTSTPCGECDSCVALapgGPGS-LDVTEIDAASHGGVDDAREL 108
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944375488  78 LDNVQYRPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPPYVKFLLATTDPQKLPITILSRCLQFHLKSLDQTQIAKQL 157
Cdd:PRK07764 109 RERAFFAPAESRYKIFIIDEAHMVTPQGFNALLKIVEEPPEHLKFIFATTEPDKVIGTIRSRTHHYPFRLVPPEVMRGYL 188
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 944375488 158 EWVLDQEGQPFEPRALLALAKAADGSMRDALSLTDQALA-HGNGSVRLESVLAMLGTLDHRHLHQLLEAILRQDAPA 233
Cdd:PRK07764 189 ERICAQEGVPVEPGVLPLVIRAGGGSVRDSLSVLDQLLAgAGPEGVTYERAVALLGVTDSALIDEAVDALAAGDGAA 265
PRK05896 PRK05896
DNA polymerase III subunits gamma and tau; Validated
1-259 1.89e-69

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 235638 [Multi-domain]  Cd Length: 605  Bit Score: 225.11  E-value: 1.89e-69
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944375488   1 ALDQGRLHHAYLLSGTRGVGKTTIARILAKSLNCEQGISSHPCGVCDTCREIDQGNFVDLLEIDAASRTKVEDTRELLDN 80
Cdd:PRK05896  31 AILNNKLTHAYIFSGPRGIGKTSIAKIFAKAINCLNPKDGDCCNSCSVCESINTNQSVDIVELDAASNNGVDEIRNIIDN 110
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944375488  81 VQYRPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPPYVKFLLATTDPQKLPITILSRCLQFHLKSLDQTQIAKQLEWV 160
Cdd:PRK05896 111 INYLPTTFKYKVYIIDEAHMLSTSAWNALLKTLEEPPKHVVFIFATTEFQKIPLTIISRCQRYNFKKLNNSELQELLKSI 190
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944375488 161 LDQEGQPFEPRALLALAKAADGSMRDALSLTDQALAHGNGSVRLESVLAMLGTLDHRHLHQLLEAILRQDAPATMAKITE 240
Cdd:PRK05896 191 AKKEKIKIEDNAIDKIADLADGSLRDGLSILDQLSTFKNSEIDIEDINKTFGLVDNNKKINLIELIQKNDIEELRNLINE 270
                        250
                 ....*....|....*....
gi 944375488 241 IATLGPDFDQLHAELEGLL 259
Cdd:PRK05896 271 LESKGINFEAFCRDLINLL 289
PRK14952 PRK14952
DNA polymerase III subunits gamma/tau;
1-247 9.19e-62

DNA polymerase III subunits gamma/tau;


Pssm-ID: 237866 [Multi-domain]  Cd Length: 584  Bit Score: 204.34  E-value: 9.19e-62
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944375488   1 ALDQGRLHHAYLLSGTRGVGKTTIARILAKSLNCEQGISSHPCGVCDTCREIDQ---GNfVDLLEIDAASRTKVEDTREL 77
Cdd:PRK14952  28 ALDAGRINHAYLFSGPRGCGKTSSARILARSLNCAQGPTATPCGVCESCVALAPngpGS-IDVVELDAASHGGVDDTREL 106
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944375488  78 LDNVQYRPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPPYVKFLLATTDPQKLPITILSRCLQFHLKSLDQTQIAKQL 157
Cdd:PRK14952 107 RDRAFYAPAQSRYRIFIVDEAHMVTTAGFNALLKIVEEPPEHLIFIFATTEPEKVLPTIRSRTHHYPFRLLPPRTMRALI 186
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944375488 158 EWVLDQEGQPFEPRALLALAKAADGSMRDALSLTDQALAHGNGS-VRLESVLAMLGTLDHRHLHQLLEAILRQDAPATMA 236
Cdd:PRK14952 187 ARICEQEGVVVDDAVYPLVIRAGGGSPRDTLSVLDQLLAGAADThVTYQRALGLLGATDVALIDDAVDALAADDAAALFG 266
                        250
                 ....*....|.
gi 944375488 237 KITEIATLGPD 247
Cdd:PRK14952 267 AIESVIDAGHD 277
PRK14970 PRK14970
DNA polymerase III subunits gamma and tau; Provisional
1-266 4.41e-55

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 184934 [Multi-domain]  Cd Length: 367  Bit Score: 181.61  E-value: 4.41e-55
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944375488   1 ALDQGRLHHAYLLSGTRGVGKTTIARILAKSLNCEQGISShpcgvcdtcreiDQGNFVDLLEIDAASRTKVEDTRELLDN 80
Cdd:PRK14970  32 AIENNHLAQALLFCGPRGVGKTTCARILARKINQPGYDDP------------NEDFSFNIFELDAASNNSVDDIRNLIDQ 99
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944375488  81 VQYRPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPPYVKFLLATTDPQKLPITILSRCLQFHLKSLDQTQIAKQLEWV 160
Cdd:PRK14970 100 VRIPPQTGKYKIYIIDEVHMLSSAAFNAFLKTLEEPPAHAIFILATTEKHKIIPTILSRCQIFDFKRITIKDIKEHLAGI 179
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944375488 161 LDQEGQPFEPRALLALAKAADGSMRDALSLTDQALAHGNGSVRLESVLAMLGTLDHRHLHQLLEAILRQDAPATMAKITE 240
Cdd:PRK14970 180 AVKEGIKFEDDALHIIAQKADGALRDALSIFDRVVTFCGKNITRQAVTENLNILDYDTYINVTDLILENKIPELLLAFNE 259
                        250       260
                 ....*....|....*....|....*.
gi 944375488 241 IATLGPDFDQLHAELEGLLHRIAMAQ 266
Cdd:PRK14970 260 ILRKGFDGHHFIAGLASHFRDLMVSK 285
DNA_pol3_delta2 pfam13177
DNA polymerase III, delta subunit; DNA polymerase III, delta subunit (EC 2.7.7.7) is required ...
1-149 8.94e-55

DNA polymerase III, delta subunit; DNA polymerase III, delta subunit (EC 2.7.7.7) is required for, along with delta' subunit, the assembly of the processivity factor beta(2) onto primed DNA in the DNA polymerase III holoenzyme-catalyzed reaction. The delta subunit is also known as HolA.


Pssm-ID: 433013 [Multi-domain]  Cd Length: 161  Bit Score: 174.32  E-value: 8.94e-55
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944375488    1 ALDQGRLHHAYLLSGTRGVGKTTIARILAKSLNCEQGISSHPCGVCDTCREIDQGNFVDLLEIDAASRT-KVEDTRELLD 79
Cdd:pfam13177  12 SLENGRLSHAYLFSGPEGVGKLELALAFAKALFCEEPGDDLPCGQCRSCRRIESGNHPDLVIIEPEGQSiKIDQIRELQK 91
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944375488   80 NVQYRPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPPYVKFLLATTDPQKLPITILSRCLQFHLKSLD 149
Cdd:pfam13177  92 EFSKSPYEGKKKVYIIEDAEKMTASAANSLLKFLEEPPGNTVIILLTENPSRLLPTIRSRCQIIRFKPLS 161
holB TIGR00678
DNA polymerase III, delta' subunit; This model describes the N-terminal half of the delta' ...
1-158 1.14e-51

DNA polymerase III, delta' subunit; This model describes the N-terminal half of the delta' subunit of DNA polymerase III. Delta' is homologous to the gamma and tau subunits, which form an outgroup for phylogenetic comparison. The gamma/tau branch of the tree is much more tighly conserved than the delta' branch, and some members of that branch score more highly against this model than some proteins classisified as delta'. The noise cutoff is set to detect weakly scoring delta' subunits rather than to exclude gamma/tau subunits. At position 126-127 of the seed alignment, this family lacks the HM motif of gamma/tau; at 132 it has a near-invariant A vs. an invariant F in gamma/tau. [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 273213 [Multi-domain]  Cd Length: 188  Bit Score: 167.03  E-value: 1.14e-51
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944375488    1 ALDQGRLHHAYLLSGTRGVGKTTIARILAKSLNCEQGISSHPCGVCDTCREIDQGNFVDLLEIDA-ASRTKVEDTRELLD 79
Cdd:TIGR00678   7 ALEKGRLAHAYLFTGPEGVGKELLALALAKALLCEQRGGGEPCGECHSCRLIEAGNHPDLHRLEPeGQSIKVDQVRELVE 86
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 944375488   80 NVQYRPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPPYVKFLLATTDPQKLPITILSRCLQFHLKSLDQTQIAKQLE 158
Cdd:TIGR00678  87 FLSRTPQESGRRVVIIEDAERMNEAAANALLKTLEEPPPNTLFILITPSPEKLLPTIRSRCQRLPFPPLSEEALLQWLI 165
HolB COG0470
DNA polymerase III, delta prime subunit [Replication, recombination and repair];
1-232 1.75e-51

DNA polymerase III, delta prime subunit [Replication, recombination and repair];


Pssm-ID: 440238 [Multi-domain]  Cd Length: 289  Bit Score: 170.16  E-value: 1.75e-51
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944375488   1 ALDQGRLHHAYLLSGTRGVGKTTIARILAKSLNCEQGISSHPCGVCDtCREIDQGNFVDLLEI--DAASRT-KVEDTREL 77
Cdd:COG0470   11 AAESGRLPHALLLHGPPGIGKTTLALALARDLLCENPEGGKACGQCH-SRLMAAGNHPDLLELnpEEKSDQiGIDQIREL 89
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944375488  78 LDNVQYRPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPPYVKFLLATTDPQKLPITILSRCLQFHLKSLDQTQIAKql 157
Cdd:COG0470   90 GEFLSLTPLEGGRKVVIIDEADAMNEAAANALLKTLEEPPKNTPFILIANDPSRLLPTIRSRCQVIRFRPPSEEEALA-- 167
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 944375488 158 ewVLDQEGqpFEPRALLALAKAADGSMRDALSLTdQALAhgngsVRLESVLAMLGTLDHRHLHQLLEAILRQDAP 232
Cdd:COG0470  168 --WLREEG--VDEDALEAILRLAGGDPRAAINLL-QALA-----GRKELLEDLAALLSRDRALELLDALLKAEAL 232
PRK08058 PRK08058
DNA polymerase III subunit delta'; Validated
2-158 2.58e-31

DNA polymerase III subunit delta'; Validated


Pssm-ID: 181214 [Multi-domain]  Cd Length: 329  Bit Score: 118.49  E-value: 2.58e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944375488   2 LDQGRLHHAYLLSGTRGVGKTTIARILAKSLNCEQGISSHPCGVCDTCREIDQGNFVDLLEI--DAASrTKVEDTRELLD 79
Cdd:PRK08058  22 IAKNRLSHAYLFEGAKGTGKKATALWLAKSLFCLERNGVEPCGTCTNCKRIDSGNHPDVHLVapDGQS-IKKDQIRYLKE 100
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 944375488  80 NVQYRPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPPYVKFLLATTDPQKLPITILSRCLQFHLKSLDQTQIAKQLE 158
Cdd:PRK08058 101 EFSKSGVESNKKVYIIEHADKMTASAANSLLKFLEEPSGGTTAILLTENKHQILPTILSRCQVVEFRPLPPESLIQRLQ 179
PRK08699 PRK08699
DNA polymerase III subunit delta'; Validated
6-163 3.74e-31

DNA polymerase III subunit delta'; Validated


Pssm-ID: 181538 [Multi-domain]  Cd Length: 325  Bit Score: 118.05  E-value: 3.74e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944375488   6 RLHHAYLLSGTRGVGKTTIARILAKSLNCEQGISSH-PCGVCDTCREIDQGNFVDLLEIDAASR----------TKVEDT 74
Cdd:PRK08699  19 RRPNAWLFAGKKGIGKTAFARFAAQALLCETPAPGHkPCGECMSCHLFGQGSHPDFYEITPLSDepengrkllqIKIDAV 98
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944375488  75 RELLDNVQYRPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPPYVKFLLATTDPQKLPITILSRCLQFHLKSLDQTQia 154
Cdd:PRK08699  99 REIIDNVYLTSVRGGLRVILIHPAESMNLQAANSLLKVLEEPPPQVVFLLVSHAADKVLPTIKSRCRKMVLPAPSHEE-- 176

                 ....*....
gi 944375488 155 kQLEWVLDQ 163
Cdd:PRK08699 177 -ALAYLRER 184
PRK05707 PRK05707
DNA polymerase III subunit delta'; Validated
2-157 6.54e-27

DNA polymerase III subunit delta'; Validated


Pssm-ID: 180215 [Multi-domain]  Cd Length: 328  Bit Score: 106.71  E-value: 6.54e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944375488   2 LDQGRLHHAYLLSGTRGVGKTTIARILAKSLNCEQGISSHPCGVCDTCREIDQGNFVDL--LEIDAASRT-KVEDTRELL 78
Cdd:PRK05707  16 AGRGRHPHAYLLHGPAGIGKRALAERLAAALLCEAPQGGGACGSCKGCQLLRAGSHPDNfvLEPEEADKTiKVDQVRELV 95
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944375488  79 DNVQYRPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPPYVKFLLATTDPQKLPITILSRCLQ--FHLKSLDQTQ--IA 154
Cdd:PRK05707  96 SFVVQTAQLGGRKVVLIEPAEAMNRNAANALLKSLEEPSGDTVLLLISHQPSRLLPTIKSRCQQqaCPLPSNEESLqwLQ 175

                 ...
gi 944375488 155 KQL 157
Cdd:PRK05707 176 QAL 178
PRK07471 PRK07471
DNA polymerase III subunit delta'; Validated
5-240 1.56e-22

DNA polymerase III subunit delta'; Validated


Pssm-ID: 236022 [Multi-domain]  Cd Length: 365  Bit Score: 95.10  E-value: 1.56e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944375488   5 GRLHHAYLLSGTRGVGKTTIARILAKSL--NCEQGISSHPCGVCD--------TCREIDQGNFVDLLEI-----DAASRT 69
Cdd:PRK07471  38 GRLHHAWLIGGPQGIGKATLAYRMARFLlaTPPPGGDGAVPPPTSlaidpdhpVARRIAAGAHGGLLTLerswnEKGKRL 117
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944375488  70 K----VEDTRELLDNVQYRPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPPYVKFLLATTDPQKLPITILSRCLQFHL 145
Cdd:PRK07471 118 RtvitVDEVRELISFFGLTAAEGGWRVVIVDTADEMNANAANALLKVLEEPPARSLFLLVSHAPARLLPTIRSRCRKLRL 197
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944375488 146 KSLDQTQIAKqlewVLDQEGQPFEPRALLALAKAADGSMRDALSLTDQ-ALA-HGngsvRLESVLAMLGTLDHRHLHQLL 223
Cdd:PRK07471 198 RPLAPEDVID----ALAAAGPDLPDDPRAALAALAEGSVGRALRLAGGdGLAlYR----RLTALLDTLPRLDRRALHALA 269
                        250
                 ....*....|....*..
gi 944375488 224 EAILRQDAPATMAKITE 240
Cdd:PRK07471 270 DAAAGRDRAARFALFLD 286
PRK07940 PRK07940
DNA polymerase III subunit delta'; Validated
9-157 4.01e-22

DNA polymerase III subunit delta'; Validated


Pssm-ID: 236134 [Multi-domain]  Cd Length: 394  Bit Score: 94.21  E-value: 4.01e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944375488   9 HAYLLSGTRGVGKTTIARILAKSLNCEQgISSHPCGVCDTCREIDQGNFVDLLEIdaasRTK-----VEDTRELLDNVQY 83
Cdd:PRK07940  37 HAWLFTGPPGSGRSVAARAFAAALQCTD-PDEPGCGECRACRTVLAGTHPDVRVV----APEglsigVDEVRELVTIAAR 111
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 944375488  84 RPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPPYVKFLLATTDPQKLPITILSRCLQFHLKSLDQTQIAKQL 157
Cdd:PRK07940 112 RPSTGRWRIVVIEDADRLTERAANALLKAVEEPPPRTVWLLCAPSPEDVLPTIRSRCRHVALRTPSVEAVAEVL 185
PRK06964 PRK06964
DNA polymerase III subunit delta'; Validated
4-145 4.10e-22

DNA polymerase III subunit delta'; Validated


Pssm-ID: 235898 [Multi-domain]  Cd Length: 342  Bit Score: 93.67  E-value: 4.10e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944375488   4 QGRLHHAYLLSGTRGVGKTTIARILAKSLNCE-QGISSHPCGVCDTCREIDQGNFVD--------------LLEIDAA-- 66
Cdd:PRK06964  17 RARLPHALLLHGQAGIGKLDFAQHLAQGLLCEtPQPDGEPCGTCAACNWFAQGNHPDyrivrpealaaeapGAADEAKea 96
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944375488  67 --------SRT-----KVEDTRELLDNVQYRPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPPYVKFLLATTDPQKLP 133
Cdd:PRK06964  97 dadeggkkTKApskeiKIEQVRALLDFCGVGTHRGGARVVVLYPAEALNVAAANALLKTLEEPPPGTVFLLVSARIDRLL 176
                        170
                 ....*....|..
gi 944375488 134 ITILSRCLQFHL 145
Cdd:PRK06964 177 PTILSRCRQFPM 188
PRK06871 PRK06871
DNA polymerase III subunit delta'; Validated
1-163 2.96e-21

DNA polymerase III subunit delta'; Validated


Pssm-ID: 180738 [Multi-domain]  Cd Length: 325  Bit Score: 90.95  E-value: 2.96e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944375488   1 ALDQGRLHHAYLLSGTRGVGKTTIARILAKSLNCEQGISSHPCGVCDTCREIDQGNFVDLLEIdAASRTK---VEDTREL 77
Cdd:PRK06871  17 AFQQGLGHHALLFKADSGLGTEQLIRALAQWLMCQTPQGDQPCGQCHSCHLFQAGNHPDFHIL-EPIDNKdigVDQVREI 95
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944375488  78 LDNVQYRPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPPYVKFLLATTDPQKLPITILSRClQFHLKSLDQTQIAkqL 157
Cdd:PRK06871  96 NEKVSQHAQQGGNKVVYIQGAERLTEAAANALLKTLEEPRPNTYFLLQADLSAALLPTIYSRC-QTWLIHPPEEQQA--L 172

                 ....*.
gi 944375488 158 EWVLDQ 163
Cdd:PRK06871 173 DWLQAQ 178
PRK07276 PRK07276
DNA polymerase III subunit delta'; Validated
2-146 2.91e-20

DNA polymerase III subunit delta'; Validated


Pssm-ID: 180916 [Multi-domain]  Cd Length: 290  Bit Score: 87.76  E-value: 2.91e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944375488   2 LDQGRLHHAYLLSGtrGVGKTTIARILAKSLNCEQGISSHPCGVCDTCREIDQGNFVDLLEIDAASRT-KVEDTRELLDN 80
Cdd:PRK07276  18 LEQDRLNHAYLFSG--DFASFEMALFLAQSLFCEQKEGVLPCGHCRSCRLIEQGEFSDVTVIEPQGQViKTDTIRELVKN 95
                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 944375488  81 VQYRPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPPYVKFLLATTDPQKLPITILSRCLQFHLK 146
Cdd:PRK07276  96 FSQSGYEGKQQVFIIKDADKMHVNAANSLLKVIEEPQSEIYIFLLTNDENKVLPTIKSRTQIFHFP 161
PRK07399 PRK07399
DNA polymerase III subunit delta'; Validated
1-164 1.04e-18

DNA polymerase III subunit delta'; Validated


Pssm-ID: 236011 [Multi-domain]  Cd Length: 314  Bit Score: 83.80  E-value: 1.04e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944375488   1 ALDQGRLHHAYLLSGTRGVGKTTIARILAKSLnceqgISSHPCGVCDTCReIDQGNFVDLLEI--------------DAA 66
Cdd:PRK07399  19 AIKQNRIAPAYLFAGPEGVGRKLAALCFIEGL-----LSQGSPSKNIRRR-LEEGNHPDLLWVeptyqhqgklitasEAE 92
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944375488  67 SRT---------KVEDTRELLDNVQYRPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPPYVkFLLATTDPQKLPITIL 137
Cdd:PRK07399  93 EAGlkrkappqiRLEQIREIKRFLSRPPLEAPRKVVVIEDAETMNEAAANALLKTLEEPGNGT-LILIAPSPESLLPTIV 171
                        170       180
                 ....*....|....*....|....*..
gi 944375488 138 SRCLQFHLKSLDQTQIAKQLEWVLDQE 164
Cdd:PRK07399 172 SRCQIIPFYRLSDEQLEQVLKRLGDEE 198
PRK09112 PRK09112
DNA polymerase III subunit delta'; Validated
1-191 3.72e-18

DNA polymerase III subunit delta'; Validated


Pssm-ID: 169667 [Multi-domain]  Cd Length: 351  Bit Score: 82.78  E-value: 3.72e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944375488   1 ALDQGRLHHAYLLSGTRGVGKTTIARILAKSLNCEQGISSHPCGVCD------TCREIDQGNFVDLLEIDAA--SRTK-- 70
Cdd:PRK09112  38 AYREGKLHHALLFEGPEGIGKATLAFHLANHILSHPDPAEAPETLADpdpaspVWRQIAQGAHPNLLHITRPfdEKTGkf 117
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944375488  71 -----VEDTRELLDNVQYRPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPPYVKFLLATTDPQKLPITILSRCLQFHL 145
Cdd:PRK09112 118 ktaitVDEIRRVGHFLSQTSGDGNWRIVIIDPADDMNRNAANAILKTLEEPPARALFILISHSSGRLLPTIRSRCQPISL 197
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*.
gi 944375488 146 KSLDQTQIAKQLEWVldQEGQPFEPRALLALAKAADGSMRDALSLT 191
Cdd:PRK09112 198 KPLDDDELKKALSHL--GSSQGSDGEITEALLQRSKGSVRKALLLL 241
PRK07993 PRK07993
DNA polymerase III subunit delta'; Validated
4-152 1.07e-17

DNA polymerase III subunit delta'; Validated


Pssm-ID: 181190 [Multi-domain]  Cd Length: 334  Bit Score: 81.27  E-value: 1.07e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944375488   4 QGRLHHAYLLSGTRGVGKTTIARILAKSLNCEQGISSHPCGVCDTCREIDQGNFVD---LLEIDAASRTKVEDTRELLDN 80
Cdd:PRK07993  20 AGRGHHALLIQALPGMGDDALIYALSRWLMCQQPQGHKSCGHCRGCQLMQAGTHPDyytLTPEKGKSSLGVDAVREVTEK 99
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 944375488  81 VQYRPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPPYVKFLLATTDPQKLPITILSRCLQFHLKSLDQTQ 152
Cdd:PRK07993 100 LYEHARLGGAKVVWLPDAALLTDAAANALLKTLEEPPENTWFFLACREPARLLATLRSRCRLHYLAPPPEQY 171
PRK06090 PRK06090
DNA polymerase III subunit delta'; Validated
1-165 9.14e-17

DNA polymerase III subunit delta'; Validated


Pssm-ID: 180394 [Multi-domain]  Cd Length: 319  Bit Score: 78.69  E-value: 9.14e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944375488   1 ALDQGRLHHAYLLSGTRGVGKTTIARILAKSLNCeQGISSHPCGVCDTCREIDQGNFVDLLEIDAASRTK---VEDTREL 77
Cdd:PRK06090  18 GLDAGRIPGALLLQSDEGLGVESLVELFSRALLC-QNYQSEACGFCHSCELMQSGNHPDLHVIKPEKEGKsitVEQIRQC 96
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944375488  78 LDNVQYRPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPPYVKFLLATTDPQKLPITILSRCLQFhlkSLDQTQIAKQL 157
Cdd:PRK06090  97 NRLAQESSQLNGYRLFVIEPADAMNESASNALLKTLEEPAPNCLFLLVTHNQKRLLPTIVSRCQQW---VVTPPSTAQAM 173

                 ....*...
gi 944375488 158 EWvLDQEG 165
Cdd:PRK06090 174 QW-LKGQG 180
PRK08769 PRK08769
DNA polymerase III subunit delta'; Validated
1-163 2.36e-16

DNA polymerase III subunit delta'; Validated


Pssm-ID: 181551 [Multi-domain]  Cd Length: 319  Bit Score: 77.31  E-value: 2.36e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944375488   1 ALDQGRLHHAYLLSGTRGVGKTTIARILAKSLnceQGISSHPCGVCDTCREIDQGNFVDLLEID-AASRTK--------V 71
Cdd:PRK08769  19 ALDAGRLGHGLLICGPEGLGKRAVALALAEHV---LASGPDPAAAQRTRQLIAAGTHPDLQLVSfIPNRTGdklrteivI 95
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944375488  72 EDTRELLDNVQYRPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPPYVKFLLATTDPQKLPITILSRC--LQFHLKSLD 149
Cdd:PRK08769  96 EQVREISQKLALTPQYGIAQVVIVDPADAINRAACNALLKTLEEPSPGRYLWLISAQPARLPATIRSRCqrLEFKLPPAH 175
                        170
                 ....*....|....
gi 944375488 150 QTqiakqLEWVLDQ 163
Cdd:PRK08769 176 EA-----LAWLLAQ 184
HLD_clamp_pol_III_gamma_tau cd18137
helical lid domain of DNA polymerase III subunits gamma and tau; DNA polymerase III subunit ...
148-212 2.86e-15

helical lid domain of DNA polymerase III subunits gamma and tau; DNA polymerase III subunit gamma/tau is part of the DNA polymerase III holoenzyme. Gamma and tau subunits are isoforms, both containing the helical lid domain. Gamma interacts with the delta subunit to transfer the beta subunit on the DNA while tau serves as a scaffold to help in the dimerization of the core complex. Both are members of the clamp-loader clade of the AAA+ superfamily.


Pssm-ID: 350839 [Multi-domain]  Cd Length: 65  Bit Score: 68.69  E-value: 2.86e-15
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 944375488 148 LDQTQIAKQLEWVLDQEGQPFEPRALLALAKAADGSMRDALSLTDQALAHGNGSVRLESVLAMLG 212
Cdd:cd18137    1 ISVEDIVGRLAHILEKEGIEIEDEALELIARAAEGSMRDALSLLDQAIAFGGGRVTLDDVREMLG 65
PRK13342 PRK13342
recombination factor protein RarA; Reviewed
1-230 2.32e-14

recombination factor protein RarA; Reviewed


Pssm-ID: 237355 [Multi-domain]  Cd Length: 413  Bit Score: 72.04  E-value: 2.32e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944375488   1 ALDQGRLHHAyLLSGTRGVGKTTIARILAKSLNCEqgisshpcgvcdtcreidqgnFVdllEIDAASrTKVEDTRELLDN 80
Cdd:PRK13342  30 MIEAGRLSSM-ILWGPPGTGKTTLARIIAGATDAP---------------------FE---ALSAVT-SGVKDLREVIEE 83
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944375488  81 VQYRPARGRFKVYLIDEVHmlsRhsFN-----ALLktleeppPYV---KFLL--ATTD-------PQklpitILSRCLQF 143
Cdd:PRK13342  84 ARQRRSAGRRTILFIDEIH---R--FNkaqqdALL-------PHVedgTITLigATTEnpsfevnPA-----LLSRAQVF 146
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944375488 144 HLKSLDQTQIAKQLEWVLDQEGqpfeprallalakaadgsmRDALSLTDQALAH----GNGSVR-----LESVLAMLGTL 214
Cdd:PRK13342 147 ELKPLSEEDIEQLLKRALEDKE-------------------RGLVELDDEALDAlarlANGDARralnlLELAALGVDSI 207
                        250
                 ....*....|....*..
gi 944375488 215 DHRHLHQLL-EAILRQD 230
Cdd:PRK13342 208 TLELLEEALqKRAARYD 224
PRK05564 PRK05564
DNA polymerase III subunit delta'; Validated
2-158 3.14e-14

DNA polymerase III subunit delta'; Validated


Pssm-ID: 180132 [Multi-domain]  Cd Length: 313  Bit Score: 71.22  E-value: 3.14e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944375488   2 LDQGRLHHAYLLSGTRGVGKTTIARILA-KSLNCEQgisshpcgvcdtcreidQGNFVDLLE--IDAASRTKVEDTRELL 78
Cdd:PRK05564  20 IIKNRFSHAHIIVGEDGIGKSLLAKEIAlKILGKSQ-----------------QREYVDIIEfkPINKKSIGVDDIRNII 82
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944375488  79 DNVQYRPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPPYVKFLLATTDPQKLPITILSRCLQFHLKSLDQTQIAKQLE 158
Cdd:PRK05564  83 EEVNKKPYEGDKKVIIIYNSEKMTEQAQNAFLKTIEEPPKGVFIILLCENLEQILDTIKSRCQIYKLNRLSKEEIEKFIS 162
PRK05917 PRK05917
DNA polymerase III subunit delta'; Validated
71-156 1.05e-13

DNA polymerase III subunit delta'; Validated


Pssm-ID: 102059 [Multi-domain]  Cd Length: 290  Bit Score: 69.44  E-value: 1.05e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944375488  71 VEDTRELLDNVQYRPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPPYVKFLLATTDPQKLPITILSRCLQFHLKSLDQ 150
Cdd:PRK05917  77 IETPRAIKKQIWIHPYESPYKIYIIHEADRMTLDAISAFLKVLEDPPQHGVIILTSAKPQRLPPTIRSRSLSIHIPMEEK 156

                 ....*.
gi 944375488 151 TQIAKQ 156
Cdd:PRK05917 157 TLVSKE 162
PRK12402 PRK12402
replication factor C small subunit 2; Reviewed
1-233 3.90e-13

replication factor C small subunit 2; Reviewed


Pssm-ID: 237090 [Multi-domain]  Cd Length: 337  Bit Score: 68.09  E-value: 3.90e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944375488   1 ALDQGRLHHaYLLSGTRGVGKTTIARILAKSLNCEQGisshpcgvcdtcreidQGNFVDLLEIDAASRTK---VEDTR-- 75
Cdd:PRK12402  30 AVDSPNLPH-LLVQGPPGSGKTAAVRALARELYGDPW----------------ENNFTEFNVADFFDQGKkylVEDPRfa 92
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944375488  76 -----------ELLDNVQ--------YRPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPPYVKFLLATTDPQKLPITI 136
Cdd:PRK12402  93 hflgtdkrirsSKIDNFKhvlkeyasYRPLSADYKTILLDNAEALREDAQQALRRIMEQYSRTCRFIIATRQPSKLIPPI 172
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944375488 137 LSRCLQFHLKSLDQTQIAKQLEWVLDQEGQPFEPRALLALAKAADGSMRDALsLTDQALAHGNGSVRLESVLAMLGTLDH 216
Cdd:PRK12402 173 RSRCLPLFFRAPTDDELVDVLESIAEAEGVDYDDDGLELIAYYAGGDLRKAI-LTLQTAALAAGEITMEAAYEALGDVGT 251
                        250
                 ....*....|....*...
gi 944375488 217 RH-LHQLLEAILRQDAPA 233
Cdd:PRK12402 252 DEvIESLLDAAEAGDFTD 269
PRK05818 PRK05818
DNA polymerase III subunit delta'; Validated
30-158 6.63e-11

DNA polymerase III subunit delta'; Validated


Pssm-ID: 235618 [Multi-domain]  Cd Length: 261  Bit Score: 61.00  E-value: 6.63e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944375488  30 KSLNCEQGISshPCGVCDTCREIDQGNFVDLLEI-DAASRTKVEDTRELLD--NVQYRPARGRfKVYLIDEVHMLSRHSF 106
Cdd:PRK05818  29 TSIVCTKANG--FCKTCESCLKILNGKYNDFYLIfDQKNPIKKEDALSIINklNRPSVESNGK-KIYIIYGIEKLNKQSA 105
                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|..
gi 944375488 107 NALLKTLEEPPPYVKFLLATTDPQKLPITILSRCLQFHLKSlDQTQIAKQLE 158
Cdd:PRK05818 106 NSLLKLIEEPPKNTYGIFTTRNENNILNTILSRCVQYVVLS-KEKKVPFKVE 156
DNA_pol3_gamma3 pfam12169
DNA polymerase III subunits gamma and tau domain III; This domain family is found in bacteria, ...
202-271 1.06e-10

DNA polymerase III subunits gamma and tau domain III; This domain family is found in bacteria, and is approximately 110 amino acids in length. The family is found in association with pfam00004. Domains I-III are shared between the tau and the gamma subunits, while most of the DnaB-binding Domain IV and all of the alpha-interacting Domain V are unique to tau.


Pssm-ID: 432379 [Multi-domain]  Cd Length: 143  Bit Score: 58.43  E-value: 1.06e-10
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944375488  202 VRLESVLAMLGTLDHRHLHQLLEAILRQDAPATMAKITEIATLGPDFDQLHAELEGLLHRIAMAQLLPAS 271
Cdd:pfam12169   1 VTAAQVRDMLGLADRGRVLDLLEALLEGDAAAALAELRDQYDAGADPVVVLRDLLELIHNLTRLKVAPDA 70
AAA pfam00004
ATPase family associated with various cellular activities (AAA); AAA family proteins often ...
11-140 1.54e-10

ATPase family associated with various cellular activities (AAA); AAA family proteins often perform chaperone-like functions that assist in the assembly, operation, or disassembly of protein complexes.


Pssm-ID: 459627 [Multi-domain]  Cd Length: 130  Bit Score: 57.60  E-value: 1.54e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944375488   11 YLLSGTRGVGKTTIARILAKSLNCEqgisshpcgvcdtCREIDQGNFVDLLEIDAASRtkvedTRELLDNVQyrpaRGRF 90
Cdd:pfam00004   1 LLLYGPPGTGKTTLAKAVAKELGAP-------------FIEISGSELVSKYVGESEKR-----LRELFEAAK----KLAP 58
                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 944375488   91 KVYLIDEVHMLSRHSF-----------NALLKTLEEP---PPYVKFLLATTDPQKLPITILSRC 140
Cdd:pfam00004  59 CVIFIDEIDALAGSRGsggdsesrrvvNQLLTELDGFtssNSKVIVIAATNRPDKLDPALLGRF 122
PRK07132 PRK07132
DNA polymerase III subunit delta'; Validated
4-157 1.87e-10

DNA polymerase III subunit delta'; Validated


Pssm-ID: 180855 [Multi-domain]  Cd Length: 299  Bit Score: 60.12  E-value: 1.87e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944375488   4 QGRLHHAYLLSGTRGVGKTTIARILAKSLNCEQGISSHPCgvcDTCREIdqgNFVDLLEiDAASRTKVEDTRELLDNVQY 83
Cdd:PRK07132  14 QNKISHSFLLKSNYNEDIDEKILYFLNKFNNLQITNLNEQ---ELPANI---ILFDIFD-KDLSKSEFLSAINKLYFSSF 86
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 944375488  84 rpARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPPYVKFLLATTDPQKLPITILSRCLQFHLKSLDQTQIAKQL 157
Cdd:PRK07132  87 --VQSQKKILIIKNIEKTSNSLLNALLKTIEEPPKDTYFLLTTKNINKVLPTIVSRCQVFNVKEPDQQKILAKL 158
44 PHA02544
clamp loader, small subunit; Provisional
2-171 3.72e-10

clamp loader, small subunit; Provisional


Pssm-ID: 222866 [Multi-domain]  Cd Length: 316  Bit Score: 59.23  E-value: 3.72e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944375488   2 LDQGRLHHAYLLSGTRGVGKTTIARILAKSLNCEQG-ISSHPCGVcDTCREidqgnfvdllEIDAASRTKVEDtrelldn 80
Cdd:PHA02544  37 VKKGRIPNMLLHSPSPGTGKTTVAKALCNEVGAEVLfVNGSDCRI-DFVRN----------RLTRFASTVSLT------- 98
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944375488  81 vqyrparGRFKVYLIDEVHMLSRHSFNALLKTL-EEPPPYVKFLLATTDPQKLPITILSRCLQFHL---KSLDQTQIAKQ 156
Cdd:PHA02544  99 -------GGGKVIIIDEFDRLGLADAQRHLRSFmEAYSKNCSFIITANNKNGIIEPLRSRCRVIDFgvpTKEEQIEMMKQ 171
                        170
                 ....*....|....*....
gi 944375488 157 L----EWVLDQEGQPFEPR 171
Cdd:PHA02544 172 MivrcKGILEAEGVEVDMK 190
RarA COG2256
Replication-associated recombination protein RarA (DNA-dependent ATPase) [Replication, ...
1-232 1.08e-09

Replication-associated recombination protein RarA (DNA-dependent ATPase) [Replication, recombination and repair];


Pssm-ID: 441857 [Multi-domain]  Cd Length: 439  Bit Score: 58.53  E-value: 1.08e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944375488   1 ALDQGRLHHAyLLSGTRGVGKTTIARILAKSLNCEqgisshpcgvcdtcreidqgnFVDLleidAASRTKVEDTRELLDN 80
Cdd:COG2256   43 AIEAGRLSSM-ILWGPPGTGKTTLARLIANATDAE---------------------FVAL----SAVTSGVKDIREVIEE 96
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944375488  81 VQYRPARGRFKVYLIDEVHmlsRhsFN-----ALLktleeppPYV---KFLL--ATTD--------PqklpitILSRCLQ 142
Cdd:COG2256   97 ARERRAYGRRTILFVDEIH---R--FNkaqqdALL-------PHVedgTITLigATTEnpsfevnsA------LLSRCRV 158
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944375488 143 FHLKSLDQTQIAKQLEWVLDQEGQpfeprallalakaadGSMRDALSLTDQALAH----GNGSVR-----LESVLAMLGT 213
Cdd:COG2256  159 FVLKPLSEEDLEQLLERALADDER---------------GLGGYKLELDDEALEAlarlADGDARralnaLELAVLSAPP 223
                        250       260
                 ....*....|....*....|
gi 944375488 214 LDHRHL-HQLLEAILRQDAP 232
Cdd:COG2256  224 DGVIEItLELVEEALQRRAL 243
AAA cd00009
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily ...
11-140 1.99e-09

The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC, RecA-like, VirD4-like, PilT-like, and SF1/2 helicases. Members of the AAA+ ATPases function as molecular chaperons, ATPase subunits of proteases, helicases, or nucleic-acid stimulated ATPases. The AAA+ proteins contain several distinct features in addition to the conserved alpha-beta-alpha core domain structure and the Walker A and B motifs of the P-loop NTPases.


Pssm-ID: 99707 [Multi-domain]  Cd Length: 151  Bit Score: 55.23  E-value: 1.99e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944375488  11 YLLSGTRGVGKTTIARILAKSLNceqgisshpcgvcdtcreidqGNFVDLLEIDAASRTKVEDTRELLDNVQYRPARGRF 90
Cdd:cd00009   22 LLLYGPPGTGKTTLARAIANELF---------------------RPGAPFLYLNASDLLEGLVVAELFGHFLVRLLFELA 80
                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 944375488  91 K-----VYLIDEVHMLSRHSFNALLKTLEEPPPY------VKFLLATTDP--QKLPITILSRC 140
Cdd:cd00009   81 EkakpgVLFIDEIDSLSRGAQNALLRVLETLNDLridrenVRVIGATNRPllGDLDRALYDRL 143
PRK04132 PRK04132
replication factor C small subunit; Provisional
59-196 1.39e-08

replication factor C small subunit; Provisional


Pssm-ID: 235223 [Multi-domain]  Cd Length: 846  Bit Score: 55.23  E-value: 1.39e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944375488  59 DLLEIDAASRTKVEDTRELL-DNVQYRPARG-RFKVYLIDEVHMLSRHSFNALLKTLEEPPPYVKFLLATTDPQKLPITI 136
Cdd:PRK04132 598 NFLELNASDERGINVIREKVkEFARTKPIGGaSFKIIFLDEADALTQDAQQALRRTMEMFSSNVRFILSCNYSSKIIEPI 677
                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 944375488 137 LSRCLQFHLKSLDQTQIAKQLEWVLDQEGQPFEPRALLALAKAADGSMRDALSLTDQALA 196
Cdd:PRK04132 678 QSRCAIFRFRPLRDEDIAKRLRYIAENEGLELTEEGLQAILYIAEGDMRRAINILQAAAA 737
rfc PRK00440
replication factor C small subunit; Reviewed
12-255 2.01e-08

replication factor C small subunit; Reviewed


Pssm-ID: 234763 [Multi-domain]  Cd Length: 319  Bit Score: 54.11  E-value: 2.01e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944375488  12 LLSGTRGVGKTTIARILAKSLnceqgisshpcgVCDTCREidqgNFvdlLEIDAAS-------RTKVEDTrelldnvqyr 84
Cdd:PRK00440  42 LFAGPPGTGKTTAALALAREL------------YGEDWRE----NF---LELNASDergidviRNKIKEF---------- 92
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944375488  85 pARGR------FKVYLIDEVHMLSRHSFNALLKTLEEPPPYVKFLLATTDPQKLPITILSRCLQFHLKSLDQTQIAKQLE 158
Cdd:PRK00440  93 -ARTApvggapFKIIFLDEADNLTSDAQQALRRTMEMYSQNTRFILSCNYSSKIIDPIQSRCAVFRFSPLKKEAVAERLR 171
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944375488 159 WVLDQEGQPFEPRALLALAKAADGSMRDALSLTdQALAHGNGSVRLESVLAMLGTLDHRHLHQLLEAILRQDAPATMAKI 238
Cdd:PRK00440 172 YIAENEGIEITDDALEAIYYVSEGDMRKAINAL-QAAAATGKEVTEEAVYKITGTARPEEIREMIELALNGDFTEAREKL 250
                        250       260
                 ....*....|....*....|..
gi 944375488 239 TEIATL----GPDF-DQLHAEL 255
Cdd:PRK00440 251 RDLMIDyglsGEDIiKQIHREV 272
PLN03025 PLN03025
replication factor C subunit; Provisional
86-245 3.51e-07

replication factor C subunit; Provisional


Pssm-ID: 178596 [Multi-domain]  Cd Length: 319  Bit Score: 50.50  E-value: 3.51e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944375488  86 ARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPPYVKFLLATTDPQKLPITILSRCLQFHLKSLDQTQIAKQLEWVLDQEG 165
Cdd:PLN03025  96 PPGRHKIVILDEADSMTSGAQQALRRTMEIYSNTTRFALACNTSSKIIEPIQSRCAIVRFSRLSDQEILGRLMKVVEAEK 175
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944375488 166 QPFEPRALLALAKAADGSMRDALSlTDQALAHGNGSVRLESVLAMLGTLDHRHLHQLLEAILRQDAPATMAKITEIATLG 245
Cdd:PLN03025 176 VPYVPEGLEAIIFTADGDMRQALN-NLQATHSGFGFVNQENVFKVCDQPHPLHVKNIVRNCLKGKFDDACDGLKQLYDLG 254
AAA smart00382
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ...
8-139 1.23e-06

ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.


Pssm-ID: 214640 [Multi-domain]  Cd Length: 148  Bit Score: 46.98  E-value: 1.23e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944375488     8 HHAYLLSGTRGVGKTTIARILAKSLNCEQGisshPCGVCDtCREIDQGNFVDLLEIDAASRTKVEDTRELLDNVQYRPAR 87
Cdd:smart00382   2 GEVILIVGPPGSGKTTLARALARELGPPGG----GVIYID-GEDILEEVLDQLLLIIVGGKKASGSGELRLRLALALARK 76
                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 944375488    88 GRFKVYLIDEVHMLSRHSFNALL-------KTLEEPPPYVKFLLATTDPQKLPITILSR 139
Cdd:smart00382  77 LKPDVLILDEITSLLDAEQEALLllleelrLLLLLKSEKNLTVILTTNDEKDLGPALLR 135
AAA_14 pfam13173
AAA domain; This family of domains contain a P-loop motif that is characteriztic of the AAA ...
8-125 2.93e-06

AAA domain; This family of domains contain a P-loop motif that is characteriztic of the AAA superfamily.


Pssm-ID: 463799 [Multi-domain]  Cd Length: 128  Bit Score: 45.66  E-value: 2.93e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944375488    8 HHAYLLSGTRGVGKTTIARILAKSLNCEQGIsshpcgvcdtcreidqgNFVDLLEIDAASRTKVEDTRELLDNVQYRPar 87
Cdd:pfam13173   2 RKILVITGPRQVGKTTLLLQLIKELLPPENI-----------------LYINLDDPRLLKLADFELLELFLELLYPGK-- 62
                          90       100       110
                  ....*....|....*....|....*....|....*...
gi 944375488   88 grfKVYLIDEVHMLSRhsFNALLKTLEEPPPYVKFLLA 125
Cdd:pfam13173  63 ---TYLFLDEIQRVPD--WELALKRLYDDGPNGRVILT 95
PRK08485 PRK08485
DNA polymerase III subunit delta'; Validated
107-167 2.32e-05

DNA polymerase III subunit delta'; Validated


Pssm-ID: 236274 [Multi-domain]  Cd Length: 206  Bit Score: 44.25  E-value: 2.32e-05
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 944375488 107 NALLKTLEEPPPYVKFLLATTDPQKLPITILSRC-------------LQFHLKSLDQTQIAKQLEWvLDQEGQP 167
Cdd:PRK08485  72 NALLKILEEPPKNICFIIVAKSKNLLLPTIRSRLiiekrkqkkpvkpLDLDLKKLDLKDIYEFLKE-LEKENKL 144
HLD_clamp cd18133
helical lid domain of clamp loader-like AAA+ proteins; Clamp loader complexes are multisubunit ...
148-211 2.75e-05

helical lid domain of clamp loader-like AAA+ proteins; Clamp loader complexes are multisubunit complexes that play an important role in DNA replication. They open sliding clamps for assembly and close them around DNA, specifically targeting them to sites where DNA synthesis is initiated and orienting them correctly for replication. The subunits belong to the clamp loader clade of AAA+ superfamily.


Pssm-ID: 350838 [Multi-domain]  Cd Length: 65  Bit Score: 41.30  E-value: 2.75e-05
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 944375488 148 LDQTQIAKQLEWVLDQEGQPFEPRALLALAKAADGSMRDALSLTDQALAHG-NGSVRLESVLAML 211
Cdd:cd18133    1 LDQEQLKRRLAAIAEQEKLKLDDAALQALAYISEGDLRKALNALQRAAALGdDGKISLDRVYQAV 65
PRK06581 PRK06581
DNA polymerase III subunit delta'; Validated
62-147 3.59e-05

DNA polymerase III subunit delta'; Validated


Pssm-ID: 235833 [Multi-domain]  Cd Length: 263  Bit Score: 44.07  E-value: 3.59e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944375488  62 EIDAASRTK---VEDTRELLDNVQYRPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPPYVKFLLATTDPQKLPITILS 138
Cdd:PRK06581  59 ETSATSNAKnisIEQIRKLQDFLSKTSAISGYKVAIIYSAELMNLNAANSCLKILEDAPKNSYIFLITSRAASIISTIRS 138

                 ....*....
gi 944375488 139 RCLQFHLKS 147
Cdd:PRK06581 139 RCFKINVRS 147
AAA_18 pfam13238
AAA domain;
12-99 5.42e-05

AAA domain;


Pssm-ID: 433052 [Multi-domain]  Cd Length: 128  Bit Score: 42.03  E-value: 5.42e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944375488   12 LLSGTRGVGKTTIARILAKSLNCEqgisshpcgvcDTCREIDQGNFVDLLEIDAASRTKVEDTR---ELLDNVQYRPARG 88
Cdd:pfam13238   2 LITGTPGVGKTTLAKELSKRLGFG-----------DNVRDLALENGLVLGDDPETRESKRLDEDkldRLLDLLEENAALE 70
                          90
                  ....*....|.
gi 944375488   89 RFKVYLIDEVH 99
Cdd:pfam13238  71 EGGNLIIDGHL 81
Fap7 COG1936
Broad-specificity NMP kinase [Nucleotide transport and metabolism];
12-35 3.13e-04

Broad-specificity NMP kinase [Nucleotide transport and metabolism];


Pssm-ID: 441539 [Multi-domain]  Cd Length: 173  Bit Score: 40.57  E-value: 3.13e-04
                         10        20
                 ....*....|....*....|....
gi 944375488  12 LLSGTRGVGKTTIARILAKSLNCE 35
Cdd:COG1936    4 AITGTPGTGKTTVAKLLAERLGLE 27
COG1373 COG1373
Predicted ATPase, AAA+ superfamily [General function prediction only];
8-125 7.87e-04

Predicted ATPase, AAA+ superfamily [General function prediction only];


Pssm-ID: 440984 [Multi-domain]  Cd Length: 405  Bit Score: 40.31  E-value: 7.87e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944375488   8 HHAYLLSGTRGVGKTTIARILAKSLnceqgisshpcgvcdtcreiDQGNFVDlLEIDAASRTKVEDTRELLDnvQYRPAR 87
Cdd:COG1373   20 RKAVVITGPRQVGKTTLLKQLAKEL--------------------ENILYIN-LDDPRLRALAEEDPDDLLE--ALKELY 76
                         90       100       110
                 ....*....|....*....|....*....|....*...
gi 944375488  88 GRFKVYLIDEVHMLsRHSFNALLKTLEEPPPYvKFLLA 125
Cdd:COG1373   77 PGKTYLFLDEIQRV-PEWEDALKRLVDDGRNG-RFILT 112
ExeA COG3267
Type II secretory pathway ATPase component GspA/ExeA/MshM [Intracellular trafficking, ...
12-165 2.96e-03

Type II secretory pathway ATPase component GspA/ExeA/MshM [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 442498 [Multi-domain]  Cd Length: 261  Bit Score: 38.23  E-value: 2.96e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944375488  12 LLSGTRGVGKTTIARILAKSL--NCEQGISSHPcgvcdtcreidQGNFVDLLE-------IDAASRTKVEDTRELLDNVQ 82
Cdd:COG3267   47 VLTGEVGTGKTTLLRRLLERLpdDVKVAYIPNP-----------QLSPAELLRaiadelgLEPKGASKADLLRQLQEFLL 115
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944375488  83 YRPARGRFKVYLIDEVHMLSRhsfnallKTLEEpppyVKFLLA-TTDPQKLPITIL-------------------SRC-L 141
Cdd:COG3267  116 ELAAAGRRVVLIIDEAQNLPP-------ETLEE----LRLLSNlETDSRKLLQIVLvgqpelrerlarpelrqlrQRItA 184
                        170       180
                 ....*....|....*....|....
gi 944375488 142 QFHLKSLDQTQIAKQLEWVLDQEG 165
Cdd:COG3267  185 RYHLRPLDREETAAYIEHRLKVAG 208
PRK13341 PRK13341
AAA family ATPase;
12-156 3.07e-03

AAA family ATPase;


Pssm-ID: 237354 [Multi-domain]  Cd Length: 725  Bit Score: 38.88  E-value: 3.07e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944375488  12 LLSGTRGVGKTTIARILAKSLNCEqgisshpcgvcdtcreidqgnFVDLleidAASRTKVEDTRELLDNVQYRPARGRFK 91
Cdd:PRK13341  56 ILYGPPGVGKTTLARIIANHTRAH---------------------FSSL----NAVLAGVKDLRAEVDRAKERLERHGKR 110
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 944375488  92 VYL-IDEVHMLSRHSFNALLKTLEEPPpyVKFLLATTDPQKLPI--TILSRCLQFHLKSL---DQTQIAKQ 156
Cdd:PRK13341 111 TILfIDEVHRFNKAQQDALLPWVENGT--ITLIGATTENPYFEVnkALVSRSRLFRLKSLsdeDLHQLLKR 179
SK cd00464
Shikimate kinase (SK) is the fifth enzyme in the shikimate pathway, a seven-step biosynthetic ...
15-35 3.61e-03

Shikimate kinase (SK) is the fifth enzyme in the shikimate pathway, a seven-step biosynthetic pathway which converts erythrose-4-phosphate to chorismic acid, found in bacteria, fungi and plants. Chorismic acid is a important intermediate in the synthesis of aromatic compounds, such as aromatic amino acids, p-aminobenzoic acid, folate and ubiquinone. Shikimate kinase catalyses the phosphorylation of the 3-hydroxyl group of shikimic acid using ATP.


Pssm-ID: 238260 [Multi-domain]  Cd Length: 154  Bit Score: 37.15  E-value: 3.61e-03
                         10        20
                 ....*....|....*....|.
gi 944375488  15 GTRGVGKTTIARILAKSLNCE 35
Cdd:cd00464    6 GMMGAGKTTVGRLLAKALGLP 26
AAA_22 pfam13401
AAA domain;
12-110 3.84e-03

AAA domain;


Pssm-ID: 379165 [Multi-domain]  Cd Length: 129  Bit Score: 36.55  E-value: 3.84e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 944375488   12 LLSGTRGVGKTTIARILAKSLNCEQGIS-----SHPCGVCDTCREIdqgnFVDLLEIDAASRTKVEDTRELLDNVQyrpA 86
Cdd:pfam13401   9 VLTGESGTGKTTLLRRLLEQLPEVRDSVvfvdlPSGTSPKDLLRAL----LRALGLPLSGRLSKEELLAALQQLLL---A 81
                          90       100
                  ....*....|....*....|....
gi 944375488   87 RGRFKVYLIDEVHMLSRHSFNALL 110
Cdd:pfam13401  82 LAVAVVLIIDEAQHLSLEALEELR 105
PRK03839 PRK03839
putative kinase; Provisional
13-35 4.58e-03

putative kinase; Provisional


Pssm-ID: 179660  Cd Length: 180  Bit Score: 37.01  E-value: 4.58e-03
                         10        20
                 ....*....|....*....|...
gi 944375488  13 LSGTRGVGKTTIARILAKSLNCE 35
Cdd:PRK03839   5 ITGTPGVGKTTVSKLLAEKLGYE 27
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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