ataxin 7-like protein 2, partial [Gadus morhua]
Protein Classification
List of domain hits
| Name | Accession | Description | Interval | E-value | ||
| SCA7 super family | cl07068 | SCA7, zinc-binding domain; This domain is found in the protein Sgf73/Sca7 which is a component ... |
177-215 | 2.92e-08 | ||
SCA7, zinc-binding domain; This domain is found in the protein Sgf73/Sca7 which is a component of the multihistone acetyltransferase complexes SAGA and SILK. This domain is also found in Ataxin-7, a human protein which in its polyglutamine expanded pathological form, is responsible for the neurodegenerative disease spinocerebellar ataxia 7 (SCA7). Ataxin-7 is an integral component of the mammalian SAGA-like complexes, the TATA-binding protein-free TAF-containing complex (TFTC) and the SPT3/TAF9/GCN5 acetyltransferase complex (STAGA). This domain is a minimal domain in ataxin-7-like proteins that is required for interaction with TFTC/STAGA subunits and is conserved highly through evolution. The domain contains a conserved Cys(3)His motif that binds zinc, thus indicating this to be a new zinc-binding domain. The actual alignment was detected with superfamily member pfam08313: Pssm-ID: 462422 Cd Length: 61 Bit Score: 48.75 E-value: 2.92e-08
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| Name | Accession | Description | Interval | E-value | ||
| SCA7 | pfam08313 | SCA7, zinc-binding domain; This domain is found in the protein Sgf73/Sca7 which is a component ... |
177-215 | 2.92e-08 | ||
SCA7, zinc-binding domain; This domain is found in the protein Sgf73/Sca7 which is a component of the multihistone acetyltransferase complexes SAGA and SILK. This domain is also found in Ataxin-7, a human protein which in its polyglutamine expanded pathological form, is responsible for the neurodegenerative disease spinocerebellar ataxia 7 (SCA7). Ataxin-7 is an integral component of the mammalian SAGA-like complexes, the TATA-binding protein-free TAF-containing complex (TFTC) and the SPT3/TAF9/GCN5 acetyltransferase complex (STAGA). This domain is a minimal domain in ataxin-7-like proteins that is required for interaction with TFTC/STAGA subunits and is conserved highly through evolution. The domain contains a conserved Cys(3)His motif that binds zinc, thus indicating this to be a new zinc-binding domain. Pssm-ID: 462422 Cd Length: 61 Bit Score: 48.75 E-value: 2.92e-08
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| Name | Accession | Description | Interval | E-value | ||
| SCA7 | pfam08313 | SCA7, zinc-binding domain; This domain is found in the protein Sgf73/Sca7 which is a component ... |
177-215 | 2.92e-08 | ||
SCA7, zinc-binding domain; This domain is found in the protein Sgf73/Sca7 which is a component of the multihistone acetyltransferase complexes SAGA and SILK. This domain is also found in Ataxin-7, a human protein which in its polyglutamine expanded pathological form, is responsible for the neurodegenerative disease spinocerebellar ataxia 7 (SCA7). Ataxin-7 is an integral component of the mammalian SAGA-like complexes, the TATA-binding protein-free TAF-containing complex (TFTC) and the SPT3/TAF9/GCN5 acetyltransferase complex (STAGA). This domain is a minimal domain in ataxin-7-like proteins that is required for interaction with TFTC/STAGA subunits and is conserved highly through evolution. The domain contains a conserved Cys(3)His motif that binds zinc, thus indicating this to be a new zinc-binding domain. Pssm-ID: 462422 Cd Length: 61 Bit Score: 48.75 E-value: 2.92e-08
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