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Conserved domains on  [gi|943491540|dbj|BAT23992|]
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rhamnosyl transferase [Klebsiella sp. 1756/51]

Protein Classification

glycosyltransferase family 2 protein( domain architecture ID 10135509)

glycosyltransferase family 2 protein catalyzes the transfer of saccharide moieties from a donor to an acceptor to form glycosidic bonds

CAZY:  GT2
EC:  2.4.-.-
Gene Ontology:  GO:0016757
PubMed:  9445404|12691742
SCOP:  3000077

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
GT_2_like_c cd04186
Subfamily of Glycosyltransferase Family GT2 of unknown function; GT-2 includes diverse ...
 4-251 6.95e-46

Subfamily of Glycosyltransferase Family GT2 of unknown function; GT-2 includes diverse families of glycosyltransferases with a common GT-A type structural fold, which has two tightly associated beta/alpha/beta domains that tend to form a continuous central sheet of at least eight beta-strands. These are enzymes that catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. Glycosyltransferases have been classified into more than 90 distinct sequence based families.


:

Pssm-ID: 133029 [Multi-domain]  Cd Length: 166  Bit Score: 153.10  E-value: 6.95e-46
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 943491540   4 IVVLNWNGLLDTLSCLNSLLELQEEKFKVVICDNGSSDGSVlkimnwhnelkEGLKERFPInkidlpinfssikttnnsg 83
Cdd:cd04186    1 IIIVNYNSLEYLKACLDSLLAQTYPDFEVIVVDNASTDGSV-----------ELLRELFPE------------------- 50

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 943491540  84 IYLINIGKNLGYAGGNNVGINFAlsqnDMSYVWLLNNDTEVDPHSLLKMKEAFSKDKKIGICGSRlvyfserdklqglgg 163
Cdd:cd04186   51 VRLIRNGENLGFGAGNNQGIREA----KGDYVLLLNPDTVVEPGALLELLDAAEQDPDVGIVGPK--------------- 111

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 943491540 164 vfnplfcssyhykanenatiefddevisnsidyVIGASMLISAEALNDIGVLCEDYFLYYEEIDYCLRAKNLGYRIYCAT 243
Cdd:cd04186  112 ---------------------------------VSGAFLLVRREVFEEVGGFDEDFFLYYEDVDLCLRARLAGYRVLYVP 158


                 ....*...
gi 943491540 244 ESIVYHKE 251
Cdd:cd04186  159 QAVIYHHG 166
 
Name Accession Description Interval E-value
GT_2_like_c cd04186
Subfamily of Glycosyltransferase Family GT2 of unknown function; GT-2 includes diverse ...
 4-251 6.95e-46

Subfamily of Glycosyltransferase Family GT2 of unknown function; GT-2 includes diverse families of glycosyltransferases with a common GT-A type structural fold, which has two tightly associated beta/alpha/beta domains that tend to form a continuous central sheet of at least eight beta-strands. These are enzymes that catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. Glycosyltransferases have been classified into more than 90 distinct sequence based families.


Pssm-ID: 133029 [Multi-domain]  Cd Length: 166  Bit Score: 153.10  E-value: 6.95e-46
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 943491540   4 IVVLNWNGLLDTLSCLNSLLELQEEKFKVVICDNGSSDGSVlkimnwhnelkEGLKERFPInkidlpinfssikttnnsg 83
Cdd:cd04186    1 IIIVNYNSLEYLKACLDSLLAQTYPDFEVIVVDNASTDGSV-----------ELLRELFPE------------------- 50

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 943491540  84 IYLINIGKNLGYAGGNNVGINFAlsqnDMSYVWLLNNDTEVDPHSLLKMKEAFSKDKKIGICGSRlvyfserdklqglgg 163
Cdd:cd04186   51 VRLIRNGENLGFGAGNNQGIREA----KGDYVLLLNPDTVVEPGALLELLDAAEQDPDVGIVGPK--------------- 111

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 943491540 164 vfnplfcssyhykanenatiefddevisnsidyVIGASMLISAEALNDIGVLCEDYFLYYEEIDYCLRAKNLGYRIYCAT 243
Cdd:cd04186  112 ---------------------------------VSGAFLLVRREVFEEVGGFDEDFFLYYEDVDLCLRARLAGYRVLYVP 158


                 ....*...
gi 943491540 244 ESIVYHKE 251
Cdd:cd04186  159 QAVIYHHG 166
WcaE COG1216
Glycosyltransferase, GT2 family [Carbohydrate transport and metabolism];
1-282 9.08e-45

Glycosyltransferase, GT2 family [Carbohydrate transport and metabolism];


Pssm-ID: 440829 [Multi-domain]  Cd Length: 202  Bit Score: 151.30  E-value: 9.08e-45
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 943491540   1 MVYIVVLNWNGLLDTLSCLNSLLELQEEKFKVVICDNGSSDGSVlkimnwhnelkeglkerfpinkidlpinfSSIKTTN 80
Cdd:COG1216    4 KVSVVIPTYNRPELLRRCLESLLAQTYPPFEVIVVDNGSTDGTA-----------------------------ELLAALA 54

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 943491540  81 NSGIYLINIGKNLGYAGGNNVGINFAlsqnDMSYVWLLNNDTEVDPHSLLKMKEAfskdkkigicgsrlvyfserdklqg 160
Cdd:COG1216   55 FPRVRVIRNPENLGFAAARNLGLRAA----GGDYLLFLDDDTVVEPDWLERLLAA------------------------- 105

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 943491540 161 lggvfnplfcssyhykanenatiefddevisnsidyvigASMLISAEALNDIGVLCEDYFLYYEEIDYCLRAKNLGYRIY 240
Cdd:COG1216  106 ---------------------------------------ACLLIRREVFEEVGGFDERFFLYGEDVDLCLRLRKAGYRIV 146

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|..
gi 943491540 241 CATESIVYHKEGASTqKGILSDYFWVRNRILIAKKYYPASIL 282
Cdd:COG1216  147 YVPDAVVYHLGGASS-GPLLRAYYLGRNRLLFLRKHGPRPLL 187
Glycos_transf_2 pfam00535
Glycosyl transferase family 2; Diverse family, transferring sugar from UDP-glucose, ...
 4-156 1.24e-12

Glycosyl transferase family 2; Diverse family, transferring sugar from UDP-glucose, UDP-N-acetyl- galactosamine, GDP-mannose or CDP-abequose, to a range of substrates including cellulose, dolichol phosphate and teichoic acids.


Pssm-ID: 425738 [Multi-domain]  Cd Length: 166  Bit Score: 64.72  E-value: 1.24e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 943491540    4 IVVLNWNGLLDTLSCLNSLLELQEEKFKVVICDNGSSDGSVLKIMNWHNElkeglkerfpinkidlpinfssikttnNSG 83
Cdd:pfam00535   2 VIIPTYNEEKYLLETLESLLNQTYPNFEIIVVDDGSTDGTVEIAEEYAKK---------------------------DPR 54

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 943491540   84 IYLINIGKNLGYAGGNNVGINFALSQndmsYVWLLNNDTEVDPHSLLKMKEAFSKDKKIGICGSRLVYFSERD 156
Cdd:pfam00535  55 VRVIRLPENRGKAGARNAGLRAATGD----YIAFLDADDEVPPDWLEKLVEALEEDGADVVVGSRYVIFGETG 123
 
Name Accession Description Interval E-value
GT_2_like_c cd04186
Subfamily of Glycosyltransferase Family GT2 of unknown function; GT-2 includes diverse ...
 4-251 6.95e-46

Subfamily of Glycosyltransferase Family GT2 of unknown function; GT-2 includes diverse families of glycosyltransferases with a common GT-A type structural fold, which has two tightly associated beta/alpha/beta domains that tend to form a continuous central sheet of at least eight beta-strands. These are enzymes that catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. Glycosyltransferases have been classified into more than 90 distinct sequence based families.


Pssm-ID: 133029 [Multi-domain]  Cd Length: 166  Bit Score: 153.10  E-value: 6.95e-46
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 943491540   4 IVVLNWNGLLDTLSCLNSLLELQEEKFKVVICDNGSSDGSVlkimnwhnelkEGLKERFPInkidlpinfssikttnnsg 83
Cdd:cd04186    1 IIIVNYNSLEYLKACLDSLLAQTYPDFEVIVVDNASTDGSV-----------ELLRELFPE------------------- 50

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 943491540  84 IYLINIGKNLGYAGGNNVGINFAlsqnDMSYVWLLNNDTEVDPHSLLKMKEAFSKDKKIGICGSRlvyfserdklqglgg 163
Cdd:cd04186   51 VRLIRNGENLGFGAGNNQGIREA----KGDYVLLLNPDTVVEPGALLELLDAAEQDPDVGIVGPK--------------- 111

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 943491540 164 vfnplfcssyhykanenatiefddevisnsidyVIGASMLISAEALNDIGVLCEDYFLYYEEIDYCLRAKNLGYRIYCAT 243
Cdd:cd04186  112 ---------------------------------VSGAFLLVRREVFEEVGGFDEDFFLYYEDVDLCLRARLAGYRVLYVP 158


                 ....*...
gi 943491540 244 ESIVYHKE 251
Cdd:cd04186  159 QAVIYHHG 166
WcaE COG1216
Glycosyltransferase, GT2 family [Carbohydrate transport and metabolism];
1-282 9.08e-45

Glycosyltransferase, GT2 family [Carbohydrate transport and metabolism];


Pssm-ID: 440829 [Multi-domain]  Cd Length: 202  Bit Score: 151.30  E-value: 9.08e-45
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 943491540   1 MVYIVVLNWNGLLDTLSCLNSLLELQEEKFKVVICDNGSSDGSVlkimnwhnelkeglkerfpinkidlpinfSSIKTTN 80
Cdd:COG1216    4 KVSVVIPTYNRPELLRRCLESLLAQTYPPFEVIVVDNGSTDGTA-----------------------------ELLAALA 54

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 943491540  81 NSGIYLINIGKNLGYAGGNNVGINFAlsqnDMSYVWLLNNDTEVDPHSLLKMKEAfskdkkigicgsrlvyfserdklqg 160
Cdd:COG1216   55 FPRVRVIRNPENLGFAAARNLGLRAA----GGDYLLFLDDDTVVEPDWLERLLAA------------------------- 105

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 943491540 161 lggvfnplfcssyhykanenatiefddevisnsidyvigASMLISAEALNDIGVLCEDYFLYYEEIDYCLRAKNLGYRIY 240
Cdd:COG1216  106 ---------------------------------------ACLLIRREVFEEVGGFDERFFLYGEDVDLCLRLRKAGYRIV 146

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|..
gi 943491540 241 CATESIVYHKEGASTqKGILSDYFWVRNRILIAKKYYPASIL 282
Cdd:COG1216  147 YVPDAVVYHLGGASS-GPLLRAYYLGRNRLLFLRKHGPRPLL 187
GT_2_like_b cd04185
Subfamily of Glycosyltransferase Family GT2 of unknown function; GT-2 includes diverse ...
 18-272 2.22e-23

Subfamily of Glycosyltransferase Family GT2 of unknown function; GT-2 includes diverse families of glycosyltransferases with a common GT-A type structural fold, which has two tightly associated beta/alpha/beta domains that tend to form a continuous central sheet of at least eight beta-strands. These are enzymes that catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. Glycosyltransferases have been classified into more than 90 distinct sequence based families.


Pssm-ID: 133028 [Multi-domain]  Cd Length: 202  Bit Score: 95.39  E-value: 2.22e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 943491540  18 CLNSLLELQEEKFKVVICDNGSSDGSvlkimnwhnelKEGLKERFPINKidlpinfssikttnnsgIYLINIGKNLGYAG 97
Cdd:cd04185   15 CLDALLAQTRPPDHIIVIDNASTDGT-----------AEWLTSLGDLDN-----------------IVYLRLPENLGGAG 66

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 943491540  98 GNNVGINFALsQNDMSYVWLLNNDTEVDPHSLLKMKEAFSKDKKIGICGSRLVYfserdklqglGGVFNplfcssyhyka 177
Cdd:cd04185   67 GFYEGVRRAY-ELGYDWIWLMDDDAIPDPDALEKLLAYADKDNPQFLAPLVLDP----------DGSFV----------- 124

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 943491540 178 nenatiefddevisnsidyvigaSMLISAEALNDIGVLCEDYFLYYEEIDYCLRAKNLGYRIYCaTESIVYHKEGASTQK 257
Cdd:cd04185  125 -----------------------GVLISRRVVEKIGLPDKEFFIWGDDTEYTLRASKAGPGIYV-PDAVVVHKTAINKGS 180

                        250       260
                 ....*....|....*....|..
gi 943491540 258 GILSD-------YFWVRNRILI 272
Cdd:cd04185  181 SAVVNidppwklYYGVRNRIYL 202
GT2_RfbF_like cd02526
RfbF is a putative dTDP-rhamnosyl transferase; Shigella flexneri RfbF protein is a putative ...
 18-273 5.67e-23

RfbF is a putative dTDP-rhamnosyl transferase; Shigella flexneri RfbF protein is a putative dTDP-rhamnosyl transferase. dTDP rhamnosyl transferases of Shigella flexneri add rhamnose sugars to N-acetyl-glucosamine in the O-antigen tetrasaccharide repeat. Lipopolysaccharide O antigens are important virulence determinants for many bacteria. The variations of sugar composition, the sequence of the sugars and the linkages in the O antigen provide structural diversity of the O antigen.


Pssm-ID: 133017 [Multi-domain]  Cd Length: 237  Bit Score: 95.04  E-value: 5.67e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 943491540  18 CLNSLLELQEEKFKVVICDNGSsdgsvlkimNWHNELKEGLkerfpinkidlpinfssikttNNSGIYLINIGKNLGYAG 97
Cdd:cd02526   13 LKELLAALAEQVDKVVVVDNSS---------GNDIELRLRL---------------------NSEKIELIHLGENLGIAK 62

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 943491540  98 GNNVGINFALSQNdMSYVWLLNNDTEVDPHSLLKMKEAF---SKDKKIGICGSRlvYFSERDKLQGLGGVFNPLFCSSYH 174
Cdd:cd02526   63 ALNIGIKAALENG-ADYVLLFDQDSVPPPDMVEKLLAYKilsDKNSNIGAVGPR--IIDRRTGENSPGVRKSGYKLRIQK 139

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 943491540 175 YKanENATIEfddevisnsIDYVIGASMLISAEALNDIGVLCEDYFLYYEEIDYCLRAKNLGYRIYCATESIVYHKEGAS 254
Cdd:cd02526  140 EG--EEGLKE---------VDFLITSGSLISLEALEKVGGFDEDLFIDYVDTEWCLRARSKGYKIYVVPDAVLKHELGDK 208

                        250       260
                 ....*....|....*....|....*....
gi 943491540 255 TQKGILSD----------YFWVRNRILIA 273
Cdd:cd02526  209 RVKRLGGVsvplhsplrrYYLFRNAIYLL 237
Glycos_transf_2 pfam00535
Glycosyl transferase family 2; Diverse family, transferring sugar from UDP-glucose, ...
 4-156 1.24e-12

Glycosyl transferase family 2; Diverse family, transferring sugar from UDP-glucose, UDP-N-acetyl- galactosamine, GDP-mannose or CDP-abequose, to a range of substrates including cellulose, dolichol phosphate and teichoic acids.


Pssm-ID: 425738 [Multi-domain]  Cd Length: 166  Bit Score: 64.72  E-value: 1.24e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 943491540    4 IVVLNWNGLLDTLSCLNSLLELQEEKFKVVICDNGSSDGSVLKIMNWHNElkeglkerfpinkidlpinfssikttnNSG 83
Cdd:pfam00535   2 VIIPTYNEEKYLLETLESLLNQTYPNFEIIVVDDGSTDGTVEIAEEYAKK---------------------------DPR 54

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 943491540   84 IYLINIGKNLGYAGGNNVGINFALSQndmsYVWLLNNDTEVDPHSLLKMKEAFSKDKKIGICGSRLVYFSERD 156
Cdd:pfam00535  55 VRVIRLPENRGKAGARNAGLRAATGD----YIAFLDADDEVPPDWLEKLVEALEEDGADVVVGSRYVIFGETG 123
Glyco_tranf_GTA_type cd00761
Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a ...
 4-169 1.17e-11

Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Glycosyltransferases (GTs) are enzymes that synthesize oligosaccharides, polysaccharides, and glycoconjugates by transferring the sugar moiety from an activated nucleotide-sugar donor to an acceptor molecule, which may be a growing oligosaccharide, a lipid, or a protein. Based on the stereochemistry of the donor and acceptor molecules, GTs are classified as either retaining or inverting enzymes. To date, all GT structures adopt one of two possible folds, termed GT-A fold and GT-B fold. This hierarchy includes diverse families of glycosyl transferases with a common GT-A type structural fold, which has two tightly associated beta/alpha/beta domains that tend to form a continuous central sheet of at least eight beta-strands. The majority of the proteins in this superfamily are Glycosyltransferase family 2 (GT-2) proteins. But it also includes families GT-43, GT-6, GT-8, GT13 and GT-7; which are evolutionarily related to GT-2 and share structure similarities.


Pssm-ID: 132997 [Multi-domain]  Cd Length: 156  Bit Score: 61.75  E-value: 1.17e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 943491540   4 IVVLNWNGLLDTLSCLNSLLELQEEKFKVVICDNGSSDGSVLKIMNWHNElkeglkerfpinkidlpinfssikttNNSG 83
Cdd:cd00761    1 VIIPAYNEEPYLERCLESLLAQTYPNFEVIVVDDGSTDGTLEILEEYAKK--------------------------DPRV 54

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 943491540  84 IYLINiGKNLGYAGGNNVGINFALSQndmsYVWLLNNDTEVDPHSLLKMKEAFSKDKKIGICGSRLVYFSERDKLQGLGG 163
Cdd:cd00761   55 IRVIN-EENQGLAAARNAGLKAARGE----YILFLDADDLLLPDWLERLVAELLADPEADAVGGPGNLLFRRELLEEIGG 129


                 ....*.
gi 943491540 164 VFNPLF 169
Cdd:cd00761  130 FDEALL 135
Glyco_tranf_2_3 pfam13641
Glycosyltransferase like family 2; Members of this family of prokaryotic proteins include ...
 1-268 1.00e-08

Glycosyltransferase like family 2; Members of this family of prokaryotic proteins include putative glucosyltransferase, which are involved in bacterial capsule biosynthesis.


Pssm-ID: 433372 [Multi-domain]  Cd Length: 230  Bit Score: 54.68  E-value: 1.00e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 943491540    1 MVYIVVLNWNGLLDTLSCLNSLLELQEEKFKVVICDNGSSDGSVlkimnwhnELKEGLKERFPINKIDLpinfssIKTTN 80
Cdd:pfam13641   3 DVSVVVPAFNEDSVLGRVLEAILAQPYPPVEVVVVVNPSDAETL--------DVAEEIAARFPDVRLRV------IRNAR 68

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 943491540   81 NSGIylinigknlgyaGGNNVGINFALSQNDMSYVWLLNNDTEVDPHsLLKMKEAFSKDKKIGICGSRLvyFSERDKlqg 160
Cdd:pfam13641  69 LLGP------------TGKSRGLNHGFRAVKSDLVVLHDDDSVLHPG-TLKKYVQYFDSPKVGAVGTPV--FSLNRS--- 130

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 943491540  161 lggvfNPLFCSSYHYKANENATIEFDDEVIsnSIDYVIGASMLISAEALNDIGVLCEdYFLYYEEIDYCLRAKNLGYRIY 240
Cdd:pfam13641 131 -----TMLSALGALEFALRHLRMMSLRLAL--GVLPLSGAGSAIRREVLKELGLFDP-FFLLGDDKSLGRRLRRHGWRVA 202

                         250       260
                  ....*....|....*....|....*...
gi 943491540  241 CATESIVYHKEGASTQKGILSDYFWVRN 268
Cdd:pfam13641 203 YAPDAAVRTVFPTYLAASIKQRARWVYG 230
BcsA COG1215
Glycosyltransferase, catalytic subunit of cellulose synthase and poly-beta-1, ...
 18-293 4.71e-08

Glycosyltransferase, catalytic subunit of cellulose synthase and poly-beta-1,6-N-acetylglucosamine synthase [Cell motility];


Pssm-ID: 440828 [Multi-domain]  Cd Length: 303  Bit Score: 53.59  E-value: 4.71e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 943491540  18 CLNSLLEL--QEEKFKVVICDNGSSDGSVlkimnwhnELKEGLKERFPinkidlpinfssikttnnsGIYLINIGKNLGY 95
Cdd:COG1215   47 TLRSLLAQdyPKEKLEVIVVDDGSTDETA--------EIARELAAEYP-------------------RVRVIERPENGGK 99

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 943491540  96 AGGNNVGINFAlsQNDmsYVWLLNNDTEVDPHSLLKMKEAFsKDKKIGICGsrlvyfserdklqglggvfnplfcssyhy 175
Cdd:COG1215  100 AAALNAGLKAA--RGD--IVVFLDADTVLDPDWLRRLVAAF-ADPGVGASG----------------------------- 145

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 943491540 176 kanenatiefddevisnsidyvigASMLISAEALNDIG-----VLCEDYFLyyeeidyCLRAKNLGYRIYCATESIVYHk 250
Cdd:COG1215  146 ------------------------ANLAFRREALEEVGgfdedTLGEDLDL-------SLRLLRAGYRIVYVPDAVVYE- 193

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....
gi 943491540 251 EGASTQKGILSDYF-WVRNRILIAKKyYPASILPVYLSLFVTFF 293
Cdd:COG1215  194 EAPETLRALFRQRRrWARGGLQLLLK-HRPLLRPRRLLLFLLLL 236
WcaA COG0463
Glycosyltransferase involved in cell wall bisynthesis [Cell wall/membrane/envelope biogenesis]; ...
 1-254 3.04e-07

Glycosyltransferase involved in cell wall bisynthesis [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440231 [Multi-domain]  Cd Length: 208  Bit Score: 50.09  E-value: 3.04e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 943491540   1 MVYIVVLNWNGLlDTLS-CLNSLLELQEEKFKVVICDNGSSDGSVLKImnwhnelkEGLKERFPinkidlpinfssiktt 79
Cdd:COG0463    3 LVSVVIPTYNEE-EYLEeALESLLAQTYPDFEIIVVDDGSTDGTAEIL--------RELAAKDP---------------- 57

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 943491540  80 nnsGIYLINIGKNLGYAGGNNVGInfALSQNDmsYVWLLNNDTEVDPHSLLKMKEAFSKDKKIGICGSRLVYFSERDKLQ 159
Cdd:COG0463   58 ---RIRVIRLERNRGKGAARNAGL--AAARGD--YIAFLDADDQLDPEKLEELVAALEEGPADLVYGSRLIREGESDLRR 130

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 943491540 160 GLGGVFNPLfcssyhykanenatiefddEVISNSIDYVIGAsMLISAEALNDIGV---LCEDYFLyyeeidycLRAKNLG 236
Cdd:COG0463  131 LGSRLFNLV-------------------RLLTNLPDSTSGF-RLFRREVLEELGFdegFLEDTEL--------LRALRHG 182

                        250
                 ....*....|....*...
gi 943491540 237 YRIycaTESIVYHKEGAS 254
Cdd:COG0463  183 FRI---AEVPVRYRAGES 197
CESA_like cd06423
CESA_like is the cellulose synthase superfamily; The cellulose synthase (CESA) superfamily ...
 18-158 9.11e-06

CESA_like is the cellulose synthase superfamily; The cellulose synthase (CESA) superfamily includes a wide variety of glycosyltransferase family 2 enzymes that share the common characteristic of catalyzing the elongation of polysaccharide chains. The members include cellulose synthase catalytic subunit, chitin synthase, glucan biosynthesis protein and other families of CESA-like proteins. Cellulose synthase catalyzes the polymerization reaction of cellulose, an aggregate of unbranched polymers of beta-1,4-linked glucose residues in plants, most algae, some bacteria and fungi, and even some animals. In bacteria, algae and lower eukaryotes, there is a second unrelated type of cellulose synthase (Type II), which produces acylated cellulose, a derivative of cellulose. Chitin synthase catalyzes the incorporation of GlcNAc from substrate UDP-GlcNAc into chitin, which is a linear homopolymer of beta-(1,4)-linked GlcNAc residues and Glucan Biosynthesis protein catalyzes the elongation of beta-1,2 polyglucose chains of Glucan.


Pssm-ID: 133045 [Multi-domain]  Cd Length: 180  Bit Score: 45.30  E-value: 9.11e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 943491540  18 CLNSLLELQEEKFKVVICDNGSSDGSVLKimnwhnelkegLKERFPINKIDLpinfssikttnnsgiYLINIGKNLGYAG 97
Cdd:cd06423   15 TIESLLALDYPKLEVIVVDDGSTDDTLEI-----------LEELAALYIRRV---------------LVVRDKENGGKAG 68

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 943491540  98 GNNVGINFAlsqnDMSYVWLLNNDTEVDPHSLLKMKEAFSKDKKIGICGSRLVYFSERDKL 158
Cdd:cd06423   69 ALNAGLRHA----KGDIVVVLDADTILEPDALKRLVVPFFADPKVGAVQGRVRVRNGSENL 125
GT_2_like_d cd04196
Subfamily of Glycosyltransferase Family GT2 of unknown function; GT-2 includes diverse ...
 19-212 8.53e-04

Subfamily of Glycosyltransferase Family GT2 of unknown function; GT-2 includes diverse families of glycosyltransferases with a common GT-A type structural fold, which has two tightly associated beta/alpha/beta domains that tend to form a continuous central sheet of at least eight beta-strands. These are enzymes that catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. Glycosyltransferases have been classified into more than 90 distinct sequence based families.


Pssm-ID: 133039 [Multi-domain]  Cd Length: 214  Bit Score: 39.92  E-value: 8.53e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 943491540  19 LNSLLELQEEKFKVVICDNGSSDGSVLKIMNWHNElkeglkerfpinkidlpinfssikttNNSGIYLINIGKNLGYAGg 98
Cdd:cd04196   17 LDSILAQTYKNDELIISDDGSTDGTVEIIKEYIDK--------------------------DPFIIILIRNGKNLGVAR- 69

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 943491540  99 nnvgiNF--ALSQNDMSY--------VWLlnndtevdPHSLLKMKEAFSKDKKIGICGSRLVYFSERDklqglggvfNPL 168
Cdd:cd04196   70 -----NFesLLQAADGDYvffcdqddIWL--------PDKLERLLKAFLKDDKPLLVYSDLELVDENG---------NPI 127

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....
gi 943491540 169 FCSSYHYKANENATIeFDDEVISNsidYVIGASMLISAEALNDI 212
Cdd:cd04196  128 GESFFEYQKIKPGTS-FNNLLFQN---VVTGCTMAFNRELLELA 167
Glyco_transf_21 pfam13506
Glycosyl transferase family 21; This is a family of ceramide beta-glucosyltransferases - EC:2. ...
 99-247 1.78e-03

Glycosyl transferase family 21; This is a family of ceramide beta-glucosyltransferases - EC:2.4.1.80.


Pssm-ID: 433264 [Multi-domain]  Cd Length: 173  Bit Score: 38.42  E-value: 1.78e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 943491540   99 NNVGINFALSQNDmsYVWLLNNDTEVDPHSLLKMKEAFSkDKKIGI-CGsrLVYFSERdklQGLGGVFNPLFCSSYHYKA 177
Cdd:pfam13506  20 NNLLQGLEAAKYD--LLVISDSDIRVPPDYLRDLLAPLA-DPKVGLvTS--PPVGSDP---KGLAAALEAAFFNTLAGVL 91

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 943491540  178 NENATiefddevisnSIDYVIGASMLISAEALNDIG-------VLCEDYFLyyeeiDYCLRAknLGYRIYCATESIV 247
Cdd:pfam13506  92 QAALS----------GIGFAVGMSMAFRRADLERIGgfealadYLAEDYAL-----GKLLRA--AGLKVVLSPRPIL 151
GT2_RfbC_Mx_like cd04184
Myxococcus xanthus RfbC like proteins are required for O-antigen biosynthesis; The rfbC gene ...
 98-169 3.66e-03

Myxococcus xanthus RfbC like proteins are required for O-antigen biosynthesis; The rfbC gene encodes a predicted protein of 1,276 amino acids, which is required for O-antigen biosynthesis in Myxococcus xanthus. It is a subfamily of Glycosyltransferase Family GT2, which includes diverse families of glycosyl transferases with a common GT-A type structural fold, which has two tightly associated beta/alpha/beta domains that tend to form a continuous central sheet of at least eight beta-strands. These are enzymes that catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds.


Pssm-ID: 133027 [Multi-domain]  Cd Length: 202  Bit Score: 37.95  E-value: 3.66e-03
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 943491540  98 GNNVGI----NFALSQNDMSYVWLLNNDTEVDPHSLLKMKEAFSKDKKIGicgsrLVYfSERDKLQGLGGVFNPLF 169
Cdd:cd04184   66 EENGGIsaatNSALELATGEFVALLDHDDELAPHALYEVVKALNEHPDAD-----LIY-SDEDKIDEGGKRSEPFF 135
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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