|
Name |
Accession |
Description |
Interval |
E-value |
| GT4_AmsD-like |
cd03820 |
amylovoran biosynthesis glycosyltransferase AmsD and similar proteins; This family is most ... |
10-348 |
2.40e-92 |
|
amylovoran biosynthesis glycosyltransferase AmsD and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. AmSD in Erwinia amylovora has been shown to be involved in the biosynthesis of amylovoran, the acidic exopolysaccharide acting as a virulence factor. This enzyme may be responsible for the formation of galactose alpha-1,6 linkages in amylovoran.
Pssm-ID: 340847 [Multi-domain] Cd Length: 351 Bit Score: 279.89 E-value: 2.40e-92
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 943490851 10 INIIIDGISNSGGTDRVLSMISNMFVLNNNKVTVFSLNDSI--PYYKISTEVKII---------SPSTKGRLAKLMSFVR 78
Cdd:cd03820 2 IAIVIPSISNAGGAERVAINLANHLAKKGYDVTIISLDSAEkpPFYELDDNIKIKnlgdrkyshFKLLLKYFKKVRRLRK 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 943490851 79 HVKVDNPDIIIVVSMGRLSAQIIPLLKVFKCKSEIICYDHVSIESFPtyiRMIKRIAYYLADKIVVLTDSDKrFI*DNYK 158
Cdd:cd03820 82 YLKNNKPDVVISFRTSLLTFLALIGLKSKLIVWEHNNYEAYNKGLRR---LLLRRLLYKRADKIVVLTEADK-LKKYKQP 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 943490851 159 IDNVYVIRNPSPFDENTIEPSELQhkiKKILAVGRLTYQKNFHRLINLWSKIDST--GWELCIVGEGDDYESLINLCQRL 236
Cdd:cd03820 158 NSNVVVIPNPLSFPSEEPSTNLKS---KRILAVGRLTYQKGFDLLIEAWALIAKKhpDWKLRIYGDGPEREELEKLIDKL 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 943490851 237 ELNN-IKIKKPDKNIQLLYKESSVLVMTSRYEGLPMVLIESKNFGLPVIAFDCKTGPAEIISN--DGYLVDYSNDCEFLI 313
Cdd:cd03820 235 GLEDrVKLLGPTKNIAEEYANSSIFVLSSRYEGFPMVLLEAMAYGLPIISFDCPTGPSEIIEDgeNGLLVPNGDVDALAE 314
|
330 340 350
....*....|....*....|....*....|....*
gi 943490851 314 KLEKLMFNHELRKELSLNAIKNSKNYSCENIYLQW 348
Cdd:cd03820 315 ALLRLMEDEELRKKMGKNARKNAERFSIEKIIKQW 349
|
|
| GT4_GT28_WabH-like |
cd03811 |
family 4 and family 28 glycosyltransferases similar to Klebsiella WabH; This family is most ... |
9-340 |
1.16e-43 |
|
family 4 and family 28 glycosyltransferases similar to Klebsiella WabH; This family is most closely related to the GT1 family of glycosyltransferases. WabH in Klebsiella pneumoniae has been shown to transfer a GlcNAc residue from UDP-GlcNAc onto the acceptor GalUA residue in the cellular outer core.
Pssm-ID: 340839 [Multi-domain] Cd Length: 351 Bit Score: 154.05 E-value: 1.16e-43
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 943490851 9 NINIIIDGISNsGGTDRVLSMISNMFVLNNNKVTVFSLNDSIPYYK--------ISTEVKIISPSTKGRLAKLMSFVRHV 80
Cdd:cd03811 1 KILFVIPSLSG-GGAERVLLNLANALDKRGYDVTLVLLRDEGDLDKqlngdvklIRLLIRVLKLIKLGLLKAILKLKRIL 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 943490851 81 KVDNPDIIIvvSMGRLSAQIIPLLKVFKCKSEIICYDHVSIESFPTYIRMIKRIAYYLADKIVVLTDSDKRFI*DNYKI- 159
Cdd:cd03811 80 KRAKPDVVI--SFLGFATYIVAKLAAARSKVIAWIHSSLSKLYYLKKKLLLKLKLYKKADKIVCVSKGIKEDLIRLGPSp 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 943490851 160 -DNVYVIRNPSPFDENTIEPSEL----QHKIKKILAVGRLTYQKNFHRLINLWSKI--DSTGWELCIVGEGDDYESLINL 232
Cdd:cd03811 158 pEKIEVIYNPIDIDRIRALAKEPilnePEDGPVILAVGRLDPQKGHDLLIEAFAKLrkKYPDVKLVILGDGPLREELEKL 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 943490851 233 CQRLELNN-IKIKKPDKNIQLLYKESSVLVMTSRYEGLPMVLIESKNFGLPVIAFDCkTGPAEIISN--DGYLVDySNDC 309
Cdd:cd03811 238 AKELGLAErVIFLGFQSNPYPYLKKADLFVLSSRYEGFPNVLLEAMALGTPVVSTDC-PGPREILDDgeNGLLVP-DGDA 315
|
330 340 350
....*....|....*....|....*....|.
gi 943490851 310 EFLIKLEKLMFNHELRKELSLNAIKNSKNYS 340
Cdd:cd03811 316 AALAGILAALLQKKLDAALRERLAKAQEAVF 346
|
|
| GT4_PimA-like |
cd03801 |
phosphatidyl-myo-inositol mannosyltransferase; This family is most closely related to the GT4 ... |
19-353 |
4.97e-38 |
|
phosphatidyl-myo-inositol mannosyltransferase; This family is most closely related to the GT4 family of glycosyltransferases and named after PimA in Propionibacterium freudenreichii, which is involved in the biosynthesis of phosphatidyl-myo-inositol mannosides (PIM) which are early precursors in the biosynthesis of lipomannans (LM) and lipoarabinomannans (LAM), and catalyzes the addition of a mannosyl residue from GDP-D-mannose (GDP-Man) to the position 2 of the carrier lipid phosphatidyl-myo-inositol (PI) to generate a phosphatidyl-myo-inositol bearing an alpha-1,2-linked mannose residue (PIM1). Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found mainly in certain bacteria and archaea.
Pssm-ID: 340831 [Multi-domain] Cd Length: 366 Bit Score: 139.60 E-value: 4.97e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 943490851 19 NSGGTDRVLSMISNMFVLNNNKVTVFSLNDS-IPYYKISTEVKIISPSTKGRLAKLMSFVRHVKVDN----PDIIIVVSM 93
Cdd:cd03801 12 PVGGAERHVRELARALAARGHDVTVLTPADPgEPPEELEDGVIVPLLPSLAALLRARRLLRELRPLLrlrkFDVVHAHGL 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 943490851 94 GRLSAqIIPLLKVFKCKSEIICYDHVSIESFPTYIRMIKRIAYYL-----ADKIVVLTDSDKRFI*DNYKIDN--VYVIR 166
Cdd:cd03801 92 LAALL-AALLALLLGAPLVVTLHGAEPGRLLLLLAAERRLLARAEallrrADAVIAVSEALRDELRALGGIPPekIVVIP 170
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 943490851 167 N---PSPFDENTIEPSELQHKIKKILAVGRLTYQKNFHRLINLWSKIDSTG--WELCIVG-EGDDYESLINLCQRLElNN 240
Cdd:cd03801 171 NgvdLERFSPPLRRKLGIPPDRPVLLFVGRLSPRKGVDLLLEALAKLLRRGpdVRLVIVGgDGPLRAELEELELGLG-DR 249
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 943490851 241 IKI--KKPDKNIQLLYKESSVLVMTSRYEGLPMVLIESKNFGLPVIAFDCkTGPAEIISND--GYLVDYSNDCEFLIKLE 316
Cdd:cd03801 250 VRFlgFVPDEELPALYAAADVFVLPSRYEGFGLVVLEAMAAGLPVVATDV-GGLPEVVEDGegGLVVPPDDVEALADALL 328
|
330 340 350
....*....|....*....|....*....|....*...
gi 943490851 317 KLMFNHELRKELSLNAIKN-SKNYSCENIYLQWLSVLK 353
Cdd:cd03801 329 RLLADPELRARLGRAARERvAERFSWERVAERLLDLYR 366
|
|
| GT4_CapM-like |
cd03808 |
capsular polysaccharide biosynthesis glycosyltransferase CapM and similar proteins; This ... |
37-332 |
3.25e-29 |
|
capsular polysaccharide biosynthesis glycosyltransferase CapM and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. CapM in Staphylococcus aureus is required for the synthesis of type 1 capsular polysaccharides.
Pssm-ID: 340837 [Multi-domain] Cd Length: 358 Bit Score: 115.39 E-value: 3.25e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 943490851 37 NNNKVTVFSLNDSIPYYKISTEVKIISPSTKgrLAKLMSFVRHVKVDNPDIIIVVS-----MGRLSAQIIpllKVFKCKS 111
Cdd:cd03808 36 DGDKLSDELKELGVKVIDIPILRRGINPLKD--LKALFKLYKLLKKEKPDIVHCHTpkpgiLGRLAARLA---GVPKVIY 110
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 943490851 112 EIICYDHVSIESFPTY--IRMIKRIAYYLADKIVVLTDSDKRFI*DNYKID-NVYVIRNPSPFDENTIEPSELQHKIKK- 187
Cdd:cd03808 111 TVHGLGFVFTEGKLLRllYLLLEKLALLFTDKVIFVNEDDRDLAIKKGIIKkKKTVLIPGSGVDLDRFQYSPESLPSEKv 190
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 943490851 188 -ILAVGRLTYQKNFHRLINLWSKIDSTG--WELCIVGEGDDYESLINLCQRLEL-NNIKIKKPDKNIQLLYKESSVLVMT 263
Cdd:cd03808 191 vFLFVARLLKDKGIDELIEAAKILKKKGpnVRFLLVGDGELENPSEILIEKLGLeGRIEFLGFRSDVPELLAESDVFVLP 270
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 943490851 264 SRYEGLPMVLIESKNFGLPVIAFDCkTGPAEIISND--GYLVDySNDCEFLI-KLEKLMFNHELRKELSLNA 332
Cdd:cd03808 271 SYREGLPRSLLEAMAAGRPVITTDV-PGCRELVIDGvnGFLVP-PGDVEALAdAIEKLIEDPELRKEMGEAA 340
|
|
| GT4_GtfA-like |
cd04949 |
accessory Sec system glycosyltransferase GtfA and similar proteins; This family is most ... |
28-348 |
3.56e-28 |
|
accessory Sec system glycosyltransferase GtfA and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases and is named after gtfA in Streptococcus gordonii, where it plays a role in the O-linked glycosylation of GspB, a cell surface glycoprotein involved in platelet binding. In general glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found in bacteria.
Pssm-ID: 340855 [Multi-domain] Cd Length: 328 Bit Score: 112.01 E-value: 3.56e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 943490851 28 SMISNMFVLNNNKVTVFSLNDSIPYYKISTEVKIISpstKGRLAKLMSFVRHVKVDNPDIIIVVSmgrlSAQIIPLLKVF 107
Cdd:cd04949 2 FVINNLIGWASSGIEYAQINRLKLFKEHTRPYKIIF---LNEQELFAFFIEQLNLQKGDIFISDR----PTLTGQVILNT 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 943490851 108 KCKSEIICY---DHVSIESFPTYIRMIKRIAYYLA-----DKIVVLTDSDKRFI*DNYKID-NVYVIRNPSpFDENTIEP 178
Cdd:cd04949 75 KGPAKKGAVlhnEHVKNNDDPEHSLIKNFYKYVFEnlnkyDAIIVSTEQQKQDLSERFNKYpPIFTIPVGY-VDQLDTAE 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 943490851 179 SELQHKIKKILAVGRLTYQKNFHRLINLWSKIDSTGWE--LCIVGEGDDYESLINLCQRLEL-NNIKIKKPDKNIQLLYK 255
Cdd:cd04949 154 SNHERKSNKIITISRLAPEKQLDHLIEAVAKAVKKVPEitLDIYGYGEEREKLKKLIEELHLeDNVFLKGYHSNLDQEYQ 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 943490851 256 ESSVLVMTSRYEGLPMVLIESKNFGLPVIAFDCKTGPAEIISND--GYLVDYSNDCEFLIKLEKLMFNHELRKELSLNAI 333
Cdd:cd04949 234 DAYLSLLTSQMEGFGLTLMEAIGHGLPVVSYDVKYGPSELIEDGenGYLIEKNNIDALADKIIELLNDPEKLQQFSEESY 313
|
330
....*....|....*
gi 943490851 334 KNSKNYSCENIYLQW 348
Cdd:cd04949 314 KIAEKYSTENVMEKW 328
|
|
| Glycos_transf_1 |
pfam00534 |
Glycosyl transferases group 1; Mutations in this domain of Swiss:P37287 lead to disease ... |
186-334 |
2.30e-27 |
|
Glycosyl transferases group 1; Mutations in this domain of Swiss:P37287 lead to disease (Paroxysmal Nocturnal haemoglobinuria). Members of this family transfer activated sugars to a variety of substrates, including glycogen, Fructose-6-phosphate and lipopolysaccharides. Members of this family transfer UDP, ADP, GDP or CMP linked sugars. The eukaryotic glycogen synthases may be distant members of this family.
Pssm-ID: 425737 [Multi-domain] Cd Length: 158 Bit Score: 105.43 E-value: 2.30e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 943490851 186 KKILAVGRLTYQKNFHRLINLWSKIDSTG--WELCIVGEGDDYESLINLCQRLEL-NNIKIK--KPDKNIQLLYKESSVL 260
Cdd:pfam00534 3 KIILFVGRLEPEKGLDLLIKAFALLKEKNpnLKLVIAGDGEEEKRLKKLAEKLGLgDNVIFLgfVSDEDLPELLKIADVF 82
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 943490851 261 VMTSRYEGLPMVLIESKNFGLPVIAFDCKtGPAEIISN--DGYLVDYSNDCEFLIKLEKLMFNHELRKELSLNAIK 334
Cdd:pfam00534 83 VLPSRYEGFGIVLLEAMACGLPVIASDVG-GPPEVVKDgeTGFLVKPNNAEALAEAIDKLLEDEELRERLGENARK 157
|
|
| PRK09922 |
PRK09922 |
lipopolysaccharide 1,6-galactosyltransferase; |
10-346 |
4.06e-26 |
|
lipopolysaccharide 1,6-galactosyltransferase;
Pssm-ID: 182148 [Multi-domain] Cd Length: 359 Bit Score: 107.10 E-value: 4.06e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 943490851 10 INIIIDGISNSGGTDRVLSMISNMFVLN--NNKVTVFSLND--------SIPYYKISTEVKIISPSTKGRLAKLMSFVRH 79
Cdd:PRK09922 3 IAFIGEAVSGFGGMETVISNVINTFEESkiNCEMFFFCRNDkmdkawlkEIKYAQSFSNIKLSFLRRAKHVYNFSKWLKE 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 943490851 80 VKvdnPDIIIvvSMGRLSAQIIPLL-KVFKCKSEIICYDHVSIESFPTY-IRMIKRIAYYLADKIVVltdsDKRFI*DNY 157
Cdd:PRK09922 83 TQ---PDIVI--CIDVISCLYANKArKKSGKQFKIFSWPHFSLDHKKHAeCKKITCADYHLAISSGI----KEQMMARGI 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 943490851 158 KIDNVYVIRNPSPFDENTIEPSElQHKIKKILAVGRLTY--QKNFHRLINLWSKIDSTgWELCIVGEGDDYESLINLCQR 235
Cdd:PRK09922 154 SAQRISVIYNPVEIKTIIIPPPE-RDKPAVFLYVGRLKFegQKNVKELFDGLSQTTGE-WQLHIIGDGSDFEKCKAYSRE 231
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 943490851 236 LELNNIKI-----KKPDKNIQLLYKESSVLVMTSRYEGLPMVLIESKNFGLPVIAFDCKTGPAEIISND--GYLVDYSND 308
Cdd:PRK09922 232 LGIEQRIIwhgwqSQPWEVVQQKIKNVSALLLTSKFEGFPMTLLEAMSYGIPCISSDCMSGPRDIIKPGlnGELYTPGNI 311
|
330 340 350
....*....|....*....|....*....|....*...
gi 943490851 309 CEFLIKLEKLMfnhELRKELSLNAIKNSKNYSCENIYL 346
Cdd:PRK09922 312 DEFVGKLNKVI---SGEVKYQHDAIPNSIERFYEVLYF 346
|
|
| GT4_MtfB-like |
cd03809 |
glycosyltransferases MtfB, WbpX, and similar proteins; This family is most closely related to ... |
12-349 |
3.40e-24 |
|
glycosyltransferases MtfB, WbpX, and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. MtfB (mannosyltransferase B) in E. coli has been shown to direct the growth of the O9-specific polysaccharide chain. It transfers two mannoses into the position 3 of the previously synthesized polysaccharide.
Pssm-ID: 340838 [Multi-domain] Cd Length: 362 Bit Score: 101.67 E-value: 3.40e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 943490851 12 IIIDGIS---NSGGTDR-VLSMISNMFVLNNNKVTVFSLNDSIPYYKISTEVKIISPS-TKGRLAKLMSFVRHVKV---- 82
Cdd:cd03809 2 ILIDGRSlaqRLTGIGRyTRELLKALAKNDPDESVLAVPPLPGELLRLLREYPELSLGvIKIKLWRELALLRWLQIllpk 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 943490851 83 -DNPDIIivvsmgrLSAQIIPLLKVFKCKSEIICYD-------HVSIESFPTYIRMIKRIAYYLADKIVVLTDSDKRFI* 154
Cdd:cd03809 82 kDKPDLL-------HSPHNTAPLLLKGCPQVVTIHDliplrypEFFPKRFRLYYRLLLPISLRRADAIITVSEATRDDII 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 943490851 155 DNYKI--DNVYVIRN--PSPFDENTIEPSELQHKIKK---ILAVGRLTYQKNFHRLINLWSKIDSTG--WELCIVGE-GD 224
Cdd:cd03809 155 KFYGVppEKIVVIPLgvDPSFFPPESAAVLIAKYLLPepyFLYVGTLEPRKNHERLLKAFALLKKQGgdLKLVIVGGkGW 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 943490851 225 DYESLINLCQRLELNNiKIKK----PDKNIQLLYKESSVLVMTSRYEGLPMVLIESKNFGLPVIAFDcktGPA--EIISN 298
Cdd:cd03809 235 EDEELLDLVKKLGLGG-RVRFlgyvSDEDLPALYRGARAFVFPSLYEGFGLPVLEAMACGTPVIASN---ISVlpEVAGD 310
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|.
gi 943490851 299 DGYLVDYSNDCEFLIKLEKLMFNHELRKELSLNAIKNSKNYSCENIYLQWL 349
Cdd:cd03809 311 AALYFDPLDPESIADAILRLLEDPSLREELIRKGLERAKKFSWEKTAEKTL 361
|
|
| Glyco_trans_1_4 |
pfam13692 |
Glycosyl transferases group 1; |
186-319 |
6.25e-24 |
|
Glycosyl transferases group 1;
Pssm-ID: 463957 [Multi-domain] Cd Length: 138 Bit Score: 95.27 E-value: 6.25e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 943490851 186 KKILAVGRLT-YQKNFHRLINLWSKI--DSTGWELCIVGEGDdYESLINLCQRLElNNIKIKKPDKNIQLLYKESSVLVM 262
Cdd:pfam13692 2 PVILFVGRLHpNVKGVDYLLEAVPLLrkRDNDVRLVIVGDGP-EEELEELAAGLE-DRVIFTGFVEDLAELLAAADVFVL 79
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*...
gi 943490851 263 TSRYEGLPMVLIESKNFGLPVIAFDCkTGPAEIISN-DGYLVDYSNDCEFLIKLEKLM 319
Cdd:pfam13692 80 PSLYEGFGLKLLEAMAAGLPVVATDV-GGIPELVDGeNGLLVPPGDPEALAEAILRLL 136
|
|
| GT4_UGDG-like |
cd03817 |
UDP-Glc:1,2-diacylglycerol 3-a-glucosyltransferase and similar proteins; This family is most ... |
40-345 |
1.12e-22 |
|
UDP-Glc:1,2-diacylglycerol 3-a-glucosyltransferase and similar proteins; This family is most closely related to the GT1 family of glycosyltransferases. UDP-glucose-diacylglycerol glucosyltransferase (EC 2.4.1.337, UGDG; also known as 1,2-diacylglycerol 3-glucosyltransferase) catalyzes the transfer of glucose from UDP-glucose to 1,2-diacylglycerol forming 3-D-glucosyl-1,2-diacylglycerol.
Pssm-ID: 340844 [Multi-domain] Cd Length: 372 Bit Score: 97.35 E-value: 1.12e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 943490851 40 KVTVFSLNDS-----IPYYKISTEVKIISPSTKGRLAKLM--SFVRHVKVDNPDIIIV---VSMGRLSAQI-----IPLL 104
Cdd:cd03817 33 EVYVITPSDPgaedeEEVVRYRSFSIPIRKYHRQHIPFPFkkAVIDRIKELGPDIIHThtpFSLGKLGLRIarklkIPIV 112
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 943490851 105 KVFKCK-SEIICYDHVSIESFPTYIRMIKRIAYYLADKIVVLTDSDKR-FI*DNYKiDNVYVIRNPSPFD--ENTIEPSE 180
Cdd:cd03817 113 HTYHTMyEDYLHYIPKGKLLVKAVVRKLVRRFYNHTDAVIAPSEKIKDtLREYGVK-GPIEVIPNGIDLDkfEKPLNTEE 191
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 943490851 181 L-QHKIKK----ILAVGRLTYQKNFHRLINLWSKID-STGWELCIVGEGDDYESLINLCQRLELNNIKI---KKPDKNIQ 251
Cdd:cd03817 192 RrKLGLPPdepiLLYVGRLAKEKNIDFLLRAFAELKkEPNIKLVIVGDGPEREELKELARELGLADKVIftgFVPREELP 271
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 943490851 252 LLYKESSVLVMTSRYEGLPMVLIESKNFGLPVIAFDcKTGPAEIISN--DGYLVDySNDCEFLIKLEKLMFNHELRKELS 329
Cdd:cd03817 272 EYYKAADLFVFASTTETQGLVYLEAMAAGLPVVAAK-DPAASELVEDgeNGFLFE-PNDETLAEKLLHLRENLELLRKLS 349
|
330 340
....*....|....*....|
gi 943490851 330 LNAIKNSKNY----SCENIY 345
Cdd:cd03817 350 KNAEISAREFafakSVEKLY 369
|
|
| RfaB |
COG0438 |
Glycosyltransferase involved in cell wall bisynthesis [Cell wall/membrane/envelope biogenesis]; ... |
246-353 |
1.88e-18 |
|
Glycosyltransferase involved in cell wall bisynthesis [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440207 [Multi-domain] Cd Length: 123 Bit Score: 80.03 E-value: 1.88e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 943490851 246 PDKNIQLL----YKESSVLVMTSRYEGLPMVLIESKNFGLPVIAFDCkTGPAEIISND--GYLVDYSNDCEFLIKLEKLM 319
Cdd:COG0438 6 PRKGLDLLlealLAAADVFVLPSRSEGFGLVLLEAMAAGLPVIATDV-GGLPEVIEDGetGLLVPPGDPEALAEAILRLL 84
|
90 100 110
....*....|....*....|....*....|....*
gi 943490851 320 FNHELRKELSLNAIKN-SKNYSCENIYLQWLSVLK 353
Cdd:COG0438 85 EDPELRRRLGEAARERaEERFSWEAIAERLLALYE 119
|
|
| GT4_WbnK-like |
cd03807 |
Shigella dysenteriae WbnK and similar proteins; This family is most closely related to the GT4 ... |
13-332 |
2.55e-18 |
|
Shigella dysenteriae WbnK and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. WbnK in Shigella dysenteriae has been shown to be involved in the type 7 O-antigen biosynthesis.
Pssm-ID: 340836 [Multi-domain] Cd Length: 362 Bit Score: 85.06 E-value: 2.55e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 943490851 13 IIDGIsNSGGTDRVLSMISNMFVLNNNKVTVFSLNDSIPYYK--ISTEVKIISPSTKG--RLAKLMSFVRHVKVDNPDII 88
Cdd:cd03807 5 VITGL-NVGGAETMLLRLLEHMDKSRFEHVVISLTGDGVLGEelLAAGVPVVCLGLSSgkDPGVLLRLAKLIRKRNPDVV 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 943490851 89 IVV-----SMGRLSAQIIPLLKVFKCKseiicydHVSIESFPTYIRMIK---RIAYYLADKIVVLTDSDKRFI*DNYKID 160
Cdd:cd03807 84 HTWmyhadLIGGLAAKLAGGVKVIWSV-------RSSNIPQRLTRLVRKlclLLSKFSPATVANSSAVAEFHQEQGYAKN 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 943490851 161 NVYVIRN--------PSPFDEN-TIEPSELQHKIKKILAVGRLTYQKNFHRLINLWSKIDSTG--WELCIVGEGDDYESL 229
Cdd:cd03807 157 KIVVIYNgidlfklsPDDASRArARRRLGLAEDRRVIGIVGRLHPVKDHSDLLRAAALLVETHpdLRLLLVGRGPERPNL 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 943490851 230 INLCQRLEL-NNIKIKKPDKNIQLLYKESSVLVMTSRYEGLPMVLIESKNFGLPVIAFDCKTGPAEIISNDGYLVDySND 308
Cdd:cd03807 237 ERLLLELGLeDRVHLLGERSDVPALLPAMDIFVLSSRTEGFPNALLEAMACGLPVVATDVGGAAELVDDGTGFLVP-AGD 315
|
330 340
....*....|....*....|....*
gi 943490851 309 CEFLIK-LEKLMFNHELRKELSLNA 332
Cdd:cd03807 316 PQALADaIRALLEDPEKRARLGRAA 340
|
|
| GT4_CapH-like |
cd03812 |
capsular polysaccharide biosynthesis glycosyltransferase CapH and similar proteins; This ... |
12-302 |
4.41e-18 |
|
capsular polysaccharide biosynthesis glycosyltransferase CapH and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. capH in Staphylococcus aureus has been shown to be required for the biosynthesis of the type 1 capsular polysaccharide (CP1).
Pssm-ID: 340840 [Multi-domain] Cd Length: 357 Bit Score: 84.26 E-value: 4.41e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 943490851 12 IIIDGISNSGGTDRVLSMISNMFVLNNNKVTVFSLNDSIPYYK---ISTEVKIISPSTKGR--LAKLMSFVRHVKVDNPD 86
Cdd:cd03812 3 LHIVGGMNVGGIETFLMNLYRKLDKSKIEFDFLATSDDKGEYDeelEELGGKIFYIPPKKKniIKYFIKLLKLIKKEKYD 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 943490851 87 IIIVVSmgrLSAQIIPLLKVFKCKSEI-ICYDHVSIESFPTYIRMI----KRIAYYLADKIVVLTDSDKRFI*DNYKIDN 161
Cdd:cd03812 83 IVHVHG---SSSNGIILLLAAKAGVPVrIAHSHNTKDSSIKLRKIRknvlKKLIERLSTKYLACSEDAGEWLFGEVENGK 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 943490851 162 VYVIRNPSPfDENTIEPSELQHKIKK--ILA-------VGRLTYQKNFHRLINLWSKIDSTG--WELCIVGEGDDYESLI 230
Cdd:cd03812 160 FKVIPNGID-IEKYKFNKEKRRKRRKllILEdklvlghVGRFNEQKNHSFLIDIFEELKKKNpnVKLVLVGEGELKEKIK 238
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 943490851 231 NLCQRLELN-NIKIKKPDKNIQLLYKESSVLVMTSRYEGLPMVLIESKNFGLPVIAFDCKTGPAEIISNDGYL 302
Cdd:cd03812 239 EKVKELGLEdKVIFLGFRNDVSEILSAMDVFLFPSLYEGLPLVAVEAQASGLPCLLSDTITKECDITNNVEFL 311
|
|
| GT4_WlbH-like |
cd03798 |
Bordetella parapertussis WlbH and similar proteins; This family is most closely related to the ... |
121-304 |
5.85e-16 |
|
Bordetella parapertussis WlbH and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. Staphylococcus aureus CapJ may be involved in capsule polysaccharide biosynthesis. WlbH in Bordetella parapertussis has been shown to be required for the biosynthesis of a trisaccharide that, when attached to the B. pertussis lipopolysaccharide (LPS) core (band B), generates band A LPS.
Pssm-ID: 340828 [Multi-domain] Cd Length: 376 Bit Score: 78.19 E-value: 5.85e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 943490851 121 IESFPTY--IRMIKRIAYYLADKIVVLTDSDKRFI*dNYKI--DNVYVIRNPspFDENTIEPSE----LQHKIKKILAVG 192
Cdd:cd03798 131 INVFPPRslLRKLLRWALRRAARVIAVSKALAEELV-ALGVprDRVDVIPNG--VDPARFQPEDrglgLPLDAFVILFVG 207
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 943490851 193 RLTYQKNFHRLINLWSKI--DSTGWELCIVGEGDDYESLINLCQRLEL-NNIKIKK--PDKNIQLLYKESSVLVMTSRYE 267
Cdd:cd03798 208 RLIPRKGIDLLLEAFARLakARPDVVLLIVGDGPLREALRALAEDLGLgDRVTFTGrlPHEQVPAYYRACDVFVLPSRHE 287
|
170 180 190
....*....|....*....|....*....|....*....
gi 943490851 268 GLPMVLIESKNFGLPVIAFDCKtGPAEII--SNDGYLVD 304
Cdd:cd03798 288 GFGLVLLEAMACGLPVVATDVG-GIPEVVgdPETGLLVP 325
|
|
| GT4_WbdM_like |
cd04951 |
LPS/UnPP-GlcNAc-Gal a-1,4-glucosyltransferase WbdM and similar proteins; This family is most ... |
9-348 |
1.07e-15 |
|
LPS/UnPP-GlcNAc-Gal a-1,4-glucosyltransferase WbdM and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases and is named after WbdM in Escherichia coli. In general glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found in bacteria.
Pssm-ID: 340857 [Multi-domain] Cd Length: 360 Bit Score: 77.10 E-value: 1.07e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 943490851 9 NINIIIDGISnSGGTDRVLSMISNMFVLNNNKVTVFSLNDSIPYYKISTEVKI----ISPSTKGRLAKLMSFVRHVKVDN 84
Cdd:cd04951 1 KILYVITGLG-LGGAEKQTVLLADQMFIRGHDVNIVYLTGEVEVKPLNNNIIIynlgMDKNPRSLLKALLKLKKIISAFK 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 943490851 85 PDiiiVVSMGRLSAQIIP-LLKVFKCKSEIICYDHVSIESfpTYIRM-IKRIAYYLADKIV-VLTDSDKRFI*D----NY 157
Cdd:cd04951 80 PD---VVHSHMFHANIFArFLRMLYPIPLLICTAHNKNEG--GRIRMfIYRLTDFLCDITTnVSREALDEFIAKkafsKN 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 943490851 158 KIDNVYVIRNPSPFDENTIEPSELQHKI------KKILAVGRLTYQKNFHRLINLWSKIDSTG--WELCIVGEGDDYESL 229
Cdd:cd04951 155 KSVPVYNGIDLNKFKKDINVRLKIRNKLnlkndeFVILNVGRLTEAKDYPNLLLAISELILSKndFKLLIAGDGPLRNEL 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 943490851 230 INLCQRLEL-NNIKIKKPDKNIQLLYKESSVLVMTSRYEGLPMVLIESKNFGLPVIAFDCKtGPAEIISNDGYLVDYSND 308
Cdd:cd04951 235 ERLICNLNLvDRVILLGQISNISEYYNAADLFVLSSEWEGFGLVVAEAMACERPVVATDAG-GVAEVVGDHNYVVPVSDP 313
|
330 340 350 360
....*....|....*....|....*....|....*....|.
gi 943490851 309 CEFLIKLEKLM-FNHELRKELSLNAIKNSKNYSCENIYLQW 348
Cdd:cd04951 314 QLLAEKIKEIFdMSDEERDILGNKNEYIAKNFSINTIVNEW 354
|
|
| Glycosyltransferase_GTB-type |
cd01635 |
glycosyltransferase family 1 and related proteins with GTB topology; Glycosyltransferases ... |
189-303 |
4.32e-15 |
|
glycosyltransferase family 1 and related proteins with GTB topology; Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. The structures of the formed glycoconjugates are extremely diverse, reflecting a wide range of biological functions. The members of this family share a common GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility.
Pssm-ID: 340816 [Multi-domain] Cd Length: 235 Bit Score: 73.59 E-value: 4.32e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 943490851 189 LAVGRLTYQKNFHRLINLWSKI--DSTGWELCIVGEGDDYESLINLCQRLELN----NIKIKKPDKNIQLLYKESSVLVM 262
Cdd:cd01635 114 VSVGRLVPEKGIDLLLEALALLkaRLPDLVLVLVGGGGEREEEEALAAALGLLervvIIGGLVDDEVLELLLAAADVFVL 193
|
90 100 110 120
....*....|....*....|....*....|....*....|..
gi 943490851 263 TSRYEGLPMVLIESKNFGLPVIAFDCKTGPAEII-SNDGYLV 303
Cdd:cd01635 194 PSRSEGFGLVLLEAMAAGKPVIATDVGGIPEFVVdGENGLLV 235
|
|
| GT4_WavL-like |
cd03819 |
Vibrio cholerae WavL and similar sequences; This family is most closely related to the GT4 ... |
137-332 |
8.02e-15 |
|
Vibrio cholerae WavL and similar sequences; This family is most closely related to the GT4 family of glycosyltransferases. WavL in Vibrio cholerae has been shown to be involved in the biosynthesis of the lipopolysaccharide core.
Pssm-ID: 340846 [Multi-domain] Cd Length: 345 Bit Score: 74.31 E-value: 8.02e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 943490851 137 YLADKIVVLTDSDKRFI*DNYKID--NVYVIRN---PSPFDENTIEPSELQHKIK----KILAVGRLTYQKNFHRLINLW 207
Cdd:cd03819 125 ARGDRVIAVSELVRDHLIEALGVDpeRIRVIPNgvdTDRFPPEAEAEERAQLGLPegkpVVGYVGRLSPEKGWLLLVDAA 204
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 943490851 208 SKID-STGWELCIVGEGDDYESLINLCQRLELNN-IKIKKPDKNIQLLYKESSVLVMTSRYEGLPMVLIESKNFGLPVIA 285
Cdd:cd03819 205 AELKdEPDFRLLVAGDGPERDEIRRLVERLGLRDrVTFTGFREDVPAALAASDVVVLPSLHEEFGRVALEAMACGTPVVA 284
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 943490851 286 FDcKTGPAEIISN--DGYLVDYSNDCEFLIKLEKLMFNHELRKELSLNA 332
Cdd:cd03819 285 TD-VGGAREIVVHgrTGLLVPPGDAEALADAIRAAKLLPEAREKLQAAA 332
|
|
| GT4_ExpE7-like |
cd03823 |
glycosyltransferase ExpE7 and similar proteins; This family is most closely related to the GT4 ... |
76-319 |
4.13e-14 |
|
glycosyltransferase ExpE7 and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. ExpE7 in Sinorhizobium meliloti has been shown to be involved in the biosynthesis of galactoglucans (exopolysaccharide II).
Pssm-ID: 340850 [Multi-domain] Cd Length: 357 Bit Score: 72.36 E-value: 4.13e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 943490851 76 FVRHVKVDNPDIIIVVSMGRLSAQIIPLLKVFKCKseiicYDHVSIESFPTYIR---MIKRIAYYLAdkivVLTDSDKRF 152
Cdd:cd03823 88 LARLLEDFRPDVVHTHNLSGLGASLLDAARDLGIP-----VVHTLHDYWLLCPRqflFKKGGDAVLA----PSRFTANLH 158
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 943490851 153 I*DNYKIDNVYVIRNPSPFDENTIEPSELQHKIKKILAVGRLTYQKNFHRLINLWSKIDSTGWELCIVGEGDD-YESLIN 231
Cdd:cd03823 159 EANGLFSARISVIPNAVEPDLAPPPRRRPGTERLRFGYIGRLTEEKGIDLLVEAFKRLPREDIELVIAGHGPLsDERQIE 238
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 943490851 232 LCQRLE-LNNIKIKKPDKniqlLYKESSVLVMTSR-YEGLPMVLIESKNFGLPVIAFDcKTGPAEIIS--NDGYLVDYSN 307
Cdd:cd03823 239 GGRRIAfLGRVPTDDIKD----FYEKIDVLVVPSIwPEPFGLVVREAIAAGLPVIASD-LGGIAELIQpgVNGLLFAPGD 313
|
250
....*....|..
gi 943490851 308 DCEFLIKLEKLM 319
Cdd:cd03823 314 AEDLAAAMRRLL 325
|
|
| GT4_WbuB-like |
cd03794 |
Escherichia coli WbuB and similar proteins; This family is most closely related to the GT1 ... |
47-332 |
2.58e-13 |
|
Escherichia coli WbuB and similar proteins; This family is most closely related to the GT1 family of glycosyltransferases. WbuB in E. coli is involved in the biosynthesis of the O26 O-antigen. It has been proposed to function as an N-acetyl-L-fucosamine (L-FucNAc) transferase.
Pssm-ID: 340825 [Multi-domain] Cd Length: 391 Bit Score: 70.45 E-value: 2.58e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 943490851 47 NDSIPYYKISTeVKIISPSTKGRLAKLMSFVRH------VKVDNPDIIIVVSMGRLSAQIIPLLK-VFKCKSEIICYD-- 117
Cdd:cd03794 56 KDGIRVIRVKL-GPIKKNGLIRRLLNYLSFALAallkllVREERPDVIIAYSPPITLGLAALLLKkLRGAPFILDVRDlw 134
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 943490851 118 --------HVSIESFPTYIRMIKRIAYYLADKIVVLTDSDKRFI*DNY-KIDNVYVIRN---PSPFDENTIEPSELQHKI 185
Cdd:cd03794 135 peslialgVLKKGSLLKLLKKLERKLYRLADAIIVLSPGLKEYLLRKGvPKEKIIVIPNwadLEEFKPPPKDELRKKLGL 214
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 943490851 186 --KKILA-VGRLTYQKNFHRLINLWSKIDS-TGWELCIVGEGDDYESLINLCQRLELNNIKIKK--PDKNIQLLYKESSV 259
Cdd:cd03794 215 ddKFVVVyAGNIGKAQGLETLLEAAERLKRrPDIRFLFVGDGDEKERLKELAKARGLDNVTFLGrvPKEEVPELLSAADV 294
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 943490851 260 LVMTSRYEGLPMVLIESKNF-----GLPVIAFDCKTG-PAEIISNDGYLVDYSNDCEFLIKLEKLMFNHELRKELSLNA 332
Cdd:cd03794 295 GLVPLKDNPANRGSSPSKLFeymaaGKPILASDDGGSdLAVEINGCGLVVEPGDPEALADAILELLDDPELRRAMGENG 373
|
|
| GT4_sucrose_synthase |
cd03800 |
sucrose-phosphate synthase and similar proteins; This family is most closely related to the ... |
124-350 |
9.48e-12 |
|
sucrose-phosphate synthase and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. The sucrose-phosphate synthases in this family may be unique to plants and photosynthetic bacteria. This enzyme catalyzes the synthesis of sucrose 6-phosphate from fructose 6-phosphate and uridine 5'-diphosphate-glucose, a key regulatory step of sucrose metabolism. The activity of this enzyme is regulated by phosphorylation and moderated by the concentration of various metabolites and light.
Pssm-ID: 340830 [Multi-domain] Cd Length: 398 Bit Score: 65.72 E-value: 9.48e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 943490851 124 FPTYIRMIKRIAYYLADKIVVLTDSDKRFI*DNYKIDNVYVIRNPSPFDENTIEPSE----------LQHKIKKILAVGR 193
Cdd:cd03800 149 HPSLRITAEEQILEAADRVIASTPQEADELISLYGADPSRINVVPPGVDLERFFPVDraearrarllLPPDKPVVLALGR 228
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 943490851 194 LTYQKNFHRLINLWSKI--DSTGWELCIVG-------EGDDYEsLINLCQRLELN---NIKIKKPDKNIQLLYKESSVLV 261
Cdd:cd03800 229 LDPRKGIDTLVRAFAQLpeLRELANLVLVGgpsddplSMDREE-LAELAEELGLIdrvRFPGRVSRDDLPELYRAADVFV 307
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 943490851 262 MTSRYEGLPMVLIESKNFGLPVIAfDCKTGPAEIISN--DGYLVDYSNDCEFLIKLEKLMFNHELRKELSLNAIKNSK-N 338
Cdd:cd03800 308 VPSLYEPFGLTAIEAMACGTPVVA-TAVGGLQDIVRDgrTGLLVDPHDPEALAAALRRLLDDPALWQRLSRAGLERARaH 386
|
250
....*....|..
gi 943490851 339 YSCENIYLQWLS 350
Cdd:cd03800 387 YTWESVADQLLT 398
|
|
| GT4_WfcD-like |
cd03795 |
Escherichia coli alpha-1,3-mannosyltransferase WfcD and similar proteins; This family is most ... |
170-332 |
2.00e-11 |
|
Escherichia coli alpha-1,3-mannosyltransferase WfcD and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP-linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found mainly in bacteria and eukaryotes.
Pssm-ID: 340826 [Multi-domain] Cd Length: 355 Bit Score: 64.22 E-value: 2.00e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 943490851 170 PFDENTIEPSELQHKIKKI-LAVGRLTYQKNFHRLINLWSKIDstgWELCIVGEGDDYESLINLCQRLELNNIK----IK 244
Cdd:cd03795 175 NIPRVDFENIKREKKGKKIfLFIGRLVYYKGLDYLIEAAQYLN---YPIVIGGEGPLKPDLEAQIELNLLDNVKflgrVD 251
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 943490851 245 KPDKNIqlLYKESSVLVMTS--RYEGLPMVLIESKNFGLPVIAFDCKTGpAEIISNDGY---LVDYSNDCEFLIKLEKLM 319
Cdd:cd03795 252 DEEKVI--YLHLCDVFVFPSvlRSEAFGIVLLEAMMCGKPVISTNIGTG-VPYVNNNGEtglVVPPKDPDALAEAIDKLL 328
|
170
....*....|...
gi 943490851 320 FNHELRKELSLNA 332
Cdd:cd03795 329 SDEELRESYGENA 341
|
|
| GT4-like |
cd03813 |
glycosyltransferase family 4 proteins; This family is most closely related to the GT4 family ... |
127-339 |
4.51e-10 |
|
glycosyltransferase family 4 proteins; This family is most closely related to the GT4 family of glycosyltransferases. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found mainly in bacteria, while some of them are also found in Archaea and eukaryotes.
Pssm-ID: 340841 [Multi-domain] Cd Length: 474 Bit Score: 60.81 E-value: 4.51e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 943490851 127 YIRMIKRIAYYLADKIVVLTDSDKRF-I*DNYKIDNVYVIRN---PSPFDENTIEPSElqhKIKKILA-VGRLTYQKNFH 201
Cdd:cd03813 233 FFERLGKLAYQQADKIISLYEGNRRRqIRLGADPDKTRVIPNgidIQRFAPAREERPE---KEPPVVGlVGRVVPIKDVK 309
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 943490851 202 RLINLWS-----KIDSTGWelcIVGEGDDYESLINLCQRL-----ELNNIKIKKPDkNIQLLYKESSVLVMTSRYEGLPM 271
Cdd:cd03813 310 TFIRAFKlvrraMPDAEGW---LIGPEDEDPEYAQECKRLvaslgLENKVKFLGFQ-NIKEYYPKLGLLVLTSISEGQPL 385
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 943490851 272 VLIESKNFGLPVIAFD---CKT---GPAEIISNDGYLV---DYSNDCEFLIKLEKlmfNHELRKELSLNAIKNSKNY 339
Cdd:cd03813 386 VILEAMASGVPVVATDvgsCREliyGADDALGQAGLVVppaDPEALAEALIKLLR---DPELRQAFGEAGRKRVEKY 459
|
|
| GT4-like |
cd03814 |
glycosyltransferase family 4 proteins; This family is most closely related to the GT4 family ... |
188-345 |
5.65e-10 |
|
glycosyltransferase family 4 proteins; This family is most closely related to the GT4 family of glycosyltransferases and includes a sequence annotated as alpha-D-mannose-alpha(1-6)phosphatidyl myo-inositol monomannoside transferase from Bacillus halodurans. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found mainly in bacteria and eukaryotes.
Pssm-ID: 340842 [Multi-domain] Cd Length: 365 Bit Score: 60.00 E-value: 5.65e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 943490851 188 ILAVGRLTYQKNFHRLINLWSKI-DSTGWELCIVGEGDDYESLinlcqRLELNNIK---IKKPDkniQL--LYKESSVLV 261
Cdd:cd03814 201 LLYVGRLAPEKNLEALLDADLPLaASPPVRLVVVGDGPARAEL-----EARGPDVIftgFLTGE---ELarAYASADVFV 272
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 943490851 262 MTSRYEGLPMVLIESKNFGLPVIAFDcKTGPAEIISN--DGYLVDYSNDCEFLIKLEKLMFNHELRKELSLNAIKNSKNY 339
Cdd:cd03814 273 FPSRTETFGLVVLEAMASGLPVVAAD-AGGPRDIVRPggTGALVEPGDAAAFAAALRALLEDPELRRRMAARARAEAERY 351
|
....*.
gi 943490851 340 SCENIY 345
Cdd:cd03814 352 SWEAFL 357
|
|
| GT4_Bme6-like |
cd03821 |
Brucella melitensis Bme6 and similar proteins; This family is most closely related to the GT4 ... |
183-350 |
3.17e-09 |
|
Brucella melitensis Bme6 and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. Bme6 in Brucella melitensis has been shown to be involved in the biosynthesis of a polysaccharide.
Pssm-ID: 340848 [Multi-domain] Cd Length: 377 Bit Score: 57.76 E-value: 3.17e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 943490851 183 HKIKKILAVGRLTYQKNFHRLINLWSKIDSTG--WELCIVGEGDDYESLINLCQRLELNNIKI----KKPDKNIQLLYKE 256
Cdd:cd03821 202 EDRRIILFLGRIHPKKGLDLLIRAARKLAEQGrdWHLVIAGPDDGAYPAFLQLQSSLGLGDRVtftgPLYGEAKWALYAS 281
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 943490851 257 SSVLVMTSRYEGLPMVLIESKNFGLPVIAFDCKTGPAEIISNDGYLVDySNDCEFLIKLEKLMFNHELRKELSLNA---I 333
Cdd:cd03821 282 ADLFVLPSYSENFGNVVAEALACGLPVVITDKCGLSELVEAGCGVVVD-PNVSSLAEALAEALRDPADRKRLGEMArraR 360
|
170
....*....|....*..
gi 943490851 334 KNSKNYSCENIYLQWLS 350
Cdd:cd03821 361 QVEENFSWEAVAGQLGE 377
|
|
| GT4_AmsK-like |
cd04946 |
amylovoran biosynthesis glycosyltransferase AmsK and similar proteins; This family is most ... |
198-341 |
7.85e-07 |
|
amylovoran biosynthesis glycosyltransferase AmsK and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. AmsK is involved in the biosynthesis of amylovoran, which functions as a virulence factor. It functions as a glycosyl transferase which transfers galactose from UDP-galactose to a lipid-linked amylovoran-subunit precursor. The members of this family are found mainly in bacteria and Archaea.
Pssm-ID: 340854 [Multi-domain] Cd Length: 401 Bit Score: 50.54 E-value: 7.85e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 943490851 198 KNFHRLINLWSKIDSTGWELCI----VGEGDDYESLINLCqRLELNNIKIK----KPDKNIQLLYKESS--VLVMTSRYE 267
Cdd:cd04946 237 KRIDLIIETLNSLCVAHPSICIswthIGGGPLKERLEKLA-ENKLENVKVNftgeVSNKEVKQLYKENDvdVFVNVSESE 315
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 943490851 268 GLPMVLIESKNFGLPVIAfDCKTGPAEIISND--GYLVDysNDC---EFLIKLEKLMFNHELRKELSLNAIKN------- 335
Cdd:cd04946 316 GIPVSIMEAISFGIPVIA-TNVGGTREIVENEtnGLLLD--KDPtpnEIVSSIMKFYLDGGDYKTMKISARECweerfna 392
|
....*.
gi 943490851 336 SKNYSC 341
Cdd:cd04946 393 EVNYSK 398
|
|
| GT4_ALG2-like |
cd03805 |
alpha-1,3/1,6-mannosyltransferase ALG2 and similar proteins; This family is most closely ... |
64-332 |
1.08e-06 |
|
alpha-1,3/1,6-mannosyltransferase ALG2 and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. ALG2, a 1,3-mannosyltransferase, in yeast catalyzes the mannosylation of Man(2)GlcNAc(2)-dolichol diphosphate and Man(1)GlcNAc(2)-dolichol diphosphate to form Man(3)GlcNAc(2)-dolichol diphosphate. A deficiency of this enzyme causes an abnormal accumulation of Man1GlcNAc2-PP-dolichol and Man2GlcNAc2-PP-dolichol, which is associated with a type of congenital disorders of glycosylation (CDG), designated CDG-Ii, in humans.
Pssm-ID: 340834 [Multi-domain] Cd Length: 392 Bit Score: 49.89 E-value: 1.08e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 943490851 64 PSTKGRLAKLMSFVRHV---------KVDNPDIIIV--VSMgrlsaqIIPLLKVFkCKSEIICYDHvsiesFP------- 125
Cdd:cd03805 65 RSIFGRFHALCAYLRMLylalylllfSGEKYDVFIVdqVSA------CVPLLKLF-RPSKILFYCH-----FPdqllaqr 132
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 943490851 126 -TYIRMIKRI--------AYYLADKIVVLTDSDKRFI*D------NYKIDNVYVIRNPSPFDEnTIEPSELQHKIKK--- 187
Cdd:cd03805 133 kSLLKRLYRKpfdwleefTTGMADQIVVNSNFTAGVFKKtfpslaKNPPEVLYPCVDTDSFDS-TSEDPDPGDLIAKsnk 211
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 943490851 188 --ILAVGRLTYQKN-------FHRLinlwsKIDSTGWELC--IVGEGDD---------YESLINLCQRLELNNIKI---- 243
Cdd:cd03805 212 kfFLSINRFERKKNialaieaFAKL-----KQKLPEFENVrlVIAGGYDprvaenveyLEELQRLAEELLNVEDQVlflr 286
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 943490851 244 KKPDKNIQLLYKESSVLVMTSRYEGLPMVLIESKNFGLPVIAfdCKT-GPAEIISND--GYLVDySNDCEFLIKLEKLMF 320
Cdd:cd03805 287 SISDSQKEQLLSSALALLYTPSNEHFGIVPLEAMYAGKPVIA--CNSgGPLETVVEGvtGFLCE-PTPEAFAEAMLKLAN 363
|
330
....*....|..
gi 943490851 321 NHELRKELSLNA 332
Cdd:cd03805 364 DPDLADRMGAAG 375
|
|
| Glyco_transf_4 |
pfam13439 |
Glycosyltransferase Family 4; |
21-168 |
4.82e-06 |
|
Glycosyltransferase Family 4;
Pssm-ID: 463877 [Multi-domain] Cd Length: 169 Bit Score: 46.37 E-value: 4.82e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 943490851 21 GGTDRVLSMISNMFVLNNNKVTVFSLNDSIPYYK---ISTEVKIISPSTKGRLAKLMSFV----RHVKVDNPDIIIVVSM 93
Cdd:pfam13439 1 GGVERYVLELARALARRGHEVTVVTPGGPGPLAEevvRVVRVPRVPLPLPPRLLRSLAFLrrlrRLLRRERPDVVHAHSP 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 943490851 94 GRLSAQIIPLLKVFKCKseIICYDHVSIES----------FPTYIRMIKRIAYYLADKIVVLTDSDKRFI*DNYKIDN-- 161
Cdd:pfam13439 81 FPLGLAALAARLRLGIP--LVVTYHGLFPDykrlgarlspLRRLLRRLERRLLRRADRVIAVSEAVADELRRLYGVPPek 158
|
....*..
gi 943490851 162 VYVIRNP 168
Cdd:pfam13439 159 IRVIPNG 165
|
|
| PRK15179 |
PRK15179 |
Vi polysaccharide biosynthesis protein TviE; Provisional |
219-285 |
2.23e-05 |
|
Vi polysaccharide biosynthesis protein TviE; Provisional
Pssm-ID: 185101 [Multi-domain] Cd Length: 694 Bit Score: 46.18 E-value: 2.23e-05
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 943490851 219 IVGEGDDYESLINLCQRLELNN-IKIKKPDKNIQLLYKESSVLVMTSRYEGLPMVLIESKNFGLPVIA 285
Cdd:PRK15179 553 MVGGGPLLESVREFAQRLGMGErILFTGLSRRVGYWLTQFNAFLLLSRFEGLPNVLIEAQFSGVPVVT 620
|
|
| GT4_AmsK-like |
cd03799 |
Erwinia amylovora AmsK and similar proteins; This is a family of GT4 glycosyltransferases ... |
187-285 |
2.76e-05 |
|
Erwinia amylovora AmsK and similar proteins; This is a family of GT4 glycosyltransferases found specifically in certain bacteria. AmsK in Erwinia amylovora, has been reported to be involved in the biosynthesis of amylovoran, a exopolysaccharide acting as a virulence factor.
Pssm-ID: 340829 [Multi-domain] Cd Length: 350 Bit Score: 45.52 E-value: 2.76e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 943490851 187 KILAVGRLTYQKNFHRLINLWSKIDSTG--WELCIVGEGDDYESLINLCQRLEL-NNIKIK--KPDKNIQLLYKESSVLV 261
Cdd:cd03799 176 RILTVGRLTEKKGLEYAIEAVAKLAQKYpnIEYQIIGDGDLKEQLQQLIQELNIgDCVKLLgwKPQEEIIEILDEADIFI 255
|
90 100 110
....*....|....*....|....*....|
gi 943490851 262 MTS------RYEGLPMVLIESKNFGLPVIA 285
Cdd:cd03799 256 APSvtaadgDQDGPPNTLKEAMAMGLPVIS 285
|
|
| GT4_WcaC-like |
cd03825 |
putative colanic acid biosynthesis glycosyl transferase WcaC and similar proteins; This family ... |
234-303 |
7.66e-05 |
|
putative colanic acid biosynthesis glycosyl transferase WcaC and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. Escherichia coli WcaC has been predicted to function in colanic acid biosynthesis. WcfI in Bacteroides fragilis has been shown to be involved in the capsular polysaccharide biosynthesis.
Pssm-ID: 340851 [Multi-domain] Cd Length: 364 Bit Score: 44.24 E-value: 7.66e-05
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 943490851 234 QRLELNNIKIKKPDKNIQL--LYKESSVLVMTSRYEGLPMVLIESKNFGLPVIAFDcKTGPAEIISND--GYLV 303
Cdd:cd03825 239 VILPFDIISLGYIDDDEQLvdIYSAADLFVHPSLADNLPNTLLEAMACGTPVVAFD-TGGSPEIVQHGvtGYLV 311
|
|
| PLN02871 |
PLN02871 |
UDP-sulfoquinovose:DAG sulfoquinovosyltransferase |
188-328 |
9.54e-05 |
|
UDP-sulfoquinovose:DAG sulfoquinovosyltransferase
Pssm-ID: 215469 [Multi-domain] Cd Length: 465 Bit Score: 43.93 E-value: 9.54e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 943490851 188 ILAVGRLTYQKNFHRLINLWSKIDSTGweLCIVGEGDdyeslinlcQRLELNNIKIKKPDKNIQLL--------YKESSV 259
Cdd:PLN02871 266 IVYVGRLGAEKNLDFLKRVMERLPGAR--LAFVGDGP---------YREELEKMFAGTPTVFTGMLqgdelsqaYASGDV 334
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 943490851 260 LVMTSRYEGLPMVLIESKNFGLPVIAfdCKTG--PaEIISND-----GYLVDYSNDCEFLIKLEKLMFNHELRKEL 328
Cdd:PLN02871 335 FVMPSESETLGFVVLEAMASGVPVVA--ARAGgiP-DIIPPDqegktGFLYTPGDVDDCVEKLETLLADPELRERM 407
|
|
| GT4_trehalose_phosphorylase |
cd03792 |
trehalose phosphorylase and similar proteins; Trehalose phosphorylase (TP) reversibly ... |
245-332 |
3.84e-04 |
|
trehalose phosphorylase and similar proteins; Trehalose phosphorylase (TP) reversibly catalyzes trehalose synthesis and degradation from alpha-glucose-1-phosphate (alpha-Glc-1-P) and glucose. The catalyzing activity includes the phosphorolysis of trehalose, which produce alpha-Glc-1-P and glucose, and the subsequent synthesis of trehalose. This family is most closely related to the GT4 family of glycosyltransferases.
Pssm-ID: 340823 [Multi-domain] Cd Length: 378 Bit Score: 41.92 E-value: 3.84e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 943490851 245 KPDKNIQLLYKESSVLVMTSRYEGLPMVLIESKNFGLPVIAfdCKTG--PAEIISN-DGYLVDySNDCEfLIKLEKLMFN 321
Cdd:cd03792 268 PSDQEINALQRAATVVLQLSTREGFGLTVSEALWKGKPVIA--TPAGgiPLQVIDGeTGFLVN-SVEGA-AVRILRLLTD 343
|
90
....*....|.
gi 943490851 322 HELRKELSLNA 332
Cdd:cd03792 344 PELRRKMGLAA 354
|
|
| PRK15490 |
PRK15490 |
Vi polysaccharide biosynthesis glycosyltransferase TviE; |
219-318 |
5.40e-04 |
|
Vi polysaccharide biosynthesis glycosyltransferase TviE;
Pssm-ID: 185387 [Multi-domain] Cd Length: 578 Bit Score: 41.99 E-value: 5.40e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 943490851 219 IVGEGDDYESLINLCQRLE-LNNIKIKKPDKNIQLLYKESSVLVMTSRYEGLPMVLIESKNFGLPVIAF------DC-KT 290
Cdd:PRK15490 434 LVGDGDLRAEAQKRAEQLGiLERILFVGASRDVGYWLQKMNVFILFSRYEGLPNVLIEAQMVGVPVISTpaggsaECfIE 513
|
90 100
....*....|....*....|....*...
gi 943490851 291 GPAEIISNDGYLVDYSNDCEFLIKLEKL 318
Cdd:PRK15490 514 GVSGFILDDAQTVNLDQACRYAEKLVNL 541
|
|
| GT5_Glycogen_synthase_DULL1-like |
cd03791 |
Glycogen synthase GlgA and similar proteins; This family is most closely related to the GT5 ... |
191-353 |
5.68e-04 |
|
Glycogen synthase GlgA and similar proteins; This family is most closely related to the GT5 family of glycosyltransferases. Glycogen synthase (EC:2.4.1.21) catalyzes the formation and elongation of the alpha-1,4-glucose backbone using ADP-glucose, the second and key step of glycogen biosynthesis. This family includes starch synthases of plants, such as DULL1 in Zea mays and glycogen synthases of various organisms.
Pssm-ID: 340822 [Multi-domain] Cd Length: 474 Bit Score: 41.78 E-value: 5.68e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 943490851 191 VGRLTYQKNFHRLINLWSKIDSTGWELCIVGEGDD-YESlinlcqrlELNNIKIKKPDK---NI-------QLLYKESSV 259
Cdd:cd03791 300 VGRLTEQKGVDLILDALPELLEEGGQLVVLGSGDPeYEQ--------AFRELAERYPGKvavVIgfdealaHRIYAGADF 371
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 943490851 260 LVMTSRYE--GLpmVLIESKNFGLPVIAFdcKTG----------PAEIISNdGYLVDYSNDCEFLIKLEKLM---FNHEL 324
Cdd:cd03791 372 FLMPSRFEpcGL--VQMYAMRYGTLPIVR--RTGgladtvfdydPETGEGT-GFVFEDYDAEALLAALRRALalyRNPEL 446
|
170 180
....*....|....*....|....*....
gi 943490851 325 RKELSLNAIKnsKNYSCENIYLQWLSVLK 353
Cdd:cd03791 447 WRKLQKNAMK--QDFSWDKSAKEYLELYR 473
|
|
| GT4_WbaZ-like |
cd03804 |
mannosyltransferase WbaZ and similar proteins; This family is most closely related to the GT4 ... |
127-298 |
1.02e-03 |
|
mannosyltransferase WbaZ and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. WbaZ in Salmonella enterica has been shown to possess mannosyltransferase activity.
Pssm-ID: 340833 [Multi-domain] Cd Length: 356 Bit Score: 40.73 E-value: 1.02e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 943490851 127 YIRM-----IKRIAYYLADKIVVltdsdKRFI*DNYKIDNVyVIRnpSPFDENTIEPSelQHKIKKILAVGRLTYQKNFH 201
Cdd:cd03804 146 YLRLwdvrtAQRVDLFIANSQFV-----ARRIKKFYGREST-VIY--PPVDTDAFAPA--ADKEDYYLTASRLVPYKRID 215
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 943490851 202 RLINLWSKidsTGWELCIVGEGDDYESLINLCQRlelnNIKI--KKPDKNIQLLYKESSVLVMTSRyEGLPMVLIESKNF 279
Cdd:cd03804 216 LAVEAFNE---LPKRLVVIGDGPDLDRLRAMASP----NVEFlgYQPDEVLKELLSKARAFVFAAE-EDFGIVPVEAQAC 287
|
170
....*....|....*....
gi 943490851 280 GLPVIAFDcKTGPAEIISN 298
Cdd:cd03804 288 GTPVIAFG-KGGALETVRP 305
|
|
| GT4_BshA-like |
cd04962 |
N-acetyl-alpha-D-glucosaminyl L-malate synthase BshA and similar proteins; This family is most ... |
184-334 |
3.02e-03 |
|
N-acetyl-alpha-D-glucosaminyl L-malate synthase BshA and similar proteins; This family is most closely related to the GT1 family of glycosyltransferases. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found mainly in bacteria, while some of them are also found in Archaea and eukaryotes.
Pssm-ID: 340859 [Multi-domain] Cd Length: 370 Bit Score: 39.26 E-value: 3.02e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 943490851 184 KIKKILAVGRLtyqknFHRLINlwsKIDSTgweLCIVGEGDDYESLINLCQRLELNNIKI---KKPDknIQLLYKESSVL 260
Cdd:cd04962 207 PVKRIDDVVRV-----FARVRR---KIPAK---LLLVGDGPERVPAEELARELGVEDRVLflgKQDD--VEELLSIADLF 273
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 943490851 261 VMTSRYEGLPMVLIESKNFGLPVIAFDCKtGPAEIISN--DGYLVDYsNDCEFLIK-LEKLMFNHELRKELSLNAIK 334
Cdd:cd04962 274 LLPSEKESFGLAALEAMACGVPVVSSNAG-GIPEVVKHgeTGFLSDV-GDVDAMAKsALSILEDDELYNRMGRAARK 348
|
|
| |
