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Conserved domains on  [gi|937940199|dbj|BAT15112|]
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Os11g0657100 [Oryza sativa Japonica Group]

Protein Classification

peptide chain release factor 1( domain architecture ID 11415460)

peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA

Gene Ontology:  GO:0016149

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PrfA COG0216
Protein chain release factor RF1 [Translation, ribosomal structure and biogenesis]; Protein ...
 53-408 0e+00

Protein chain release factor RF1 [Translation, ribosomal structure and biogenesis]; Protein chain release factor RF1 is part of the Pathway/BioSystem: Translation factors


:

Pssm-ID: 439986 [Multi-domain]  Cd Length: 356  Bit Score: 523.41  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937940199  53 YLIAKLDSAEKAWKEMSVRLADPDIVSDPSEYQKLAQSVAELDQVVSTYRQFKDCEKQIEETKVLQKEnEDDPDMAEMID 132
Cdd:COG0216    1 SMLDKLEALEERYEELEALLSDPEVISDQKRFRKLSKEYAELEPIVEAYREYKKLLEDIEEAKELLEE-ESDPEMREMAK 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937940199 133 SEMESLSNQLEELEEKLKLLLLPNDPLDARNILLEVRAGAGGDEAGIWAGDLVRMYQKYCERNSWKFKPVSSSEAEKGGF 212
Cdd:COG0216   80 EELEELEARLEELEEELKILLLPKDPNDDKNVILEIRAGTGGDEAALFAGDLFRMYSRYAERKGWKVEILSASEGELGGY 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937940199 213 KTYVMEVKGKQVYSKLKFESGVHRVQRVPQTETMGRVHTSTATVAIMPEADEVDVVIDPKDIELKTARSGGAGGQNVNKV 292
Cdd:COG0216  160 KEVIFRISGEGVYSRLKFESGVHRVQRVPETESQGRIHTSAATVAVLPEAEEVDVEINPKDLRIDTFRSSGAGGQHVNTT 239

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937940199 293 ETAVDLIHKPTGIRIFCTEERSQLQNRERAFQLLRAKLYEIKLREQQESIRNQRKLQVGTGARSEKIRTYNYKDNRVTDH 372
Cdd:COG0216  240 DSAVRITHLPTGIVVECQDERSQHKNKAKAMKVLRARLYEAEQQKQQAEIAAERKSQVGSGDRSERIRTYNFPQGRVTDH 319

                        330       340       350
                 ....*....|....*....|....*....|....*..
gi 937940199 373 RLKMNF-ELTGFLMGDIESAVQSCSSMEQKELLEEMA 408
Cdd:COG0216  320 RINLTLyKLDEVMEGDLDELIDALIAEDQAEKLAALE 356
 
Name Accession Description Interval E-value
PrfA COG0216
Protein chain release factor RF1 [Translation, ribosomal structure and biogenesis]; Protein ...
 53-408 0e+00

Protein chain release factor RF1 [Translation, ribosomal structure and biogenesis]; Protein chain release factor RF1 is part of the Pathway/BioSystem: Translation factors


Pssm-ID: 439986 [Multi-domain]  Cd Length: 356  Bit Score: 523.41  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937940199  53 YLIAKLDSAEKAWKEMSVRLADPDIVSDPSEYQKLAQSVAELDQVVSTYRQFKDCEKQIEETKVLQKEnEDDPDMAEMID 132
Cdd:COG0216    1 SMLDKLEALEERYEELEALLSDPEVISDQKRFRKLSKEYAELEPIVEAYREYKKLLEDIEEAKELLEE-ESDPEMREMAK 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937940199 133 SEMESLSNQLEELEEKLKLLLLPNDPLDARNILLEVRAGAGGDEAGIWAGDLVRMYQKYCERNSWKFKPVSSSEAEKGGF 212
Cdd:COG0216   80 EELEELEARLEELEEELKILLLPKDPNDDKNVILEIRAGTGGDEAALFAGDLFRMYSRYAERKGWKVEILSASEGELGGY 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937940199 213 KTYVMEVKGKQVYSKLKFESGVHRVQRVPQTETMGRVHTSTATVAIMPEADEVDVVIDPKDIELKTARSGGAGGQNVNKV 292
Cdd:COG0216  160 KEVIFRISGEGVYSRLKFESGVHRVQRVPETESQGRIHTSAATVAVLPEAEEVDVEINPKDLRIDTFRSSGAGGQHVNTT 239

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937940199 293 ETAVDLIHKPTGIRIFCTEERSQLQNRERAFQLLRAKLYEIKLREQQESIRNQRKLQVGTGARSEKIRTYNYKDNRVTDH 372
Cdd:COG0216  240 DSAVRITHLPTGIVVECQDERSQHKNKAKAMKVLRARLYEAEQQKQQAEIAAERKSQVGSGDRSERIRTYNFPQGRVTDH 319

                        330       340       350
                 ....*....|....*....|....*....|....*..
gi 937940199 373 RLKMNF-ELTGFLMGDIESAVQSCSSMEQKELLEEMA 408
Cdd:COG0216  320 RINLTLyKLDEVMEGDLDELIDALIAEDQAEKLAALE 356
prfA PRK00591
peptide chain release factor 1; Validated
 51-408 0e+00

peptide chain release factor 1; Validated


Pssm-ID: 234801 [Multi-domain]  Cd Length: 359  Bit Score: 522.33  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937940199  51 EPYLIAKLDSAEKAWKEMSVRLADPDIVSDPSEYQKLAQSVAELDQVVSTYRQFKDCEKQIEETKVLQKEnEDDPDMAEM 130
Cdd:PRK00591   1 KPSMLDKLEALEERYEELEALLSDPEVISDQKRFRKLSKEYAELEPIVEAYREYKQAQEDLEEAKEMLEE-ESDPEMREM 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937940199 131 IDSEMESLSNQLEELEEKLKLLLLPNDPLDARNILLEVRAGAGGDEAGIWAGDLVRMYQKYCERNSWKFKPVSSSEAEKG 210
Cdd:PRK00591  80 AKEELKELEERLEELEEELKILLLPKDPNDDKNVILEIRAGTGGDEAALFAGDLFRMYSRYAERQGWKVEILSASEGELG 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937940199 211 GFKTYVMEVKGKQVYSKLKFESGVHRVQRVPQTETMGRVHTSTATVAIMPEADEVDVVIDPKDIELKTARSGGAGGQNVN 290
Cdd:PRK00591 160 GYKEVIAEISGDGVYSKLKFESGVHRVQRVPATESQGRIHTSAATVAVLPEAEEVEVEINPKDLRIDTFRSSGAGGQHVN 239

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937940199 291 KVETAVDLIHKPTGIRIFCTEERSQLQNRERAFQLLRAKLYEIKLREQQESIRNQRKLQVGTGARSEKIRTYNYKDNRVT 370
Cdd:PRK00591 240 TTDSAVRITHLPTGIVVECQDERSQHKNKAKAMKVLRARLYDAERQKAQAEEAATRKSQVGSGDRSERIRTYNFPQGRVT 319

                        330       340       350
                 ....*....|....*....|....*....|....*....
gi 937940199 371 DHRLKM-NFELTGFLMGDIESAVQSCSSMEQKELLEEMA 408
Cdd:PRK00591 320 DHRINLtLYKLDEVMEGDLDELIDALIAEDQAEKLAALG 358
prfA TIGR00019
peptide chain release factor 1; This model describes peptide chain release factor 1 (PrfA, ...
 50-408 2.23e-154

peptide chain release factor 1; This model describes peptide chain release factor 1 (PrfA, RF-1), and excludes the related peptide chain release factor 2 (PrfB, RF-2). RF-1 helps recognize and terminate translation at UAA and UAG stop codons. The mitochondrial release factors are prfA-like, although not included above the trusted cutoff for this model. RF-1 does not have a translational frameshift. [Protein synthesis, Translation factors]


Pssm-ID: 129130 [Multi-domain]  Cd Length: 360  Bit Score: 440.67  E-value: 2.23e-154
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937940199   50 AEPYLIAKLDSAEKAWKEMSVRLADPDIVSDPSEYQKLAQSVAELDQVVSTYRQFKDCEKQIEETKVLQKENedDPDMAE 129
Cdd:TIGR00019   1 MKPSLLEKLESLLERYEELEALLSDPEVISDQDKLRKLSKEYSQLEEIVDCYREYQQAQEDIKEAKEILEES--DPEMRE 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937940199  130 MIDSEMESLSNQLEELEEKLKLLLLPNDPLDARNILLEVRAGAGGDEAGIWAGDLVRMYQKYCERNSWKFKPVSSSEAEK 209
Cdd:TIGR00019  79 MAKEELEELEEKIEELEEQLKVLLLPKDPNDEKNVILEIRAGTGGDEAAIFAGDLFRMYSRYAESKGWKVEILSANETEL 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937940199  210 GGFKTYVMEVKGKQVYSKLKFESGVHRVQRVPQTETMGRVHTSTATVAIMPEADEVDVVIDPKDIELKTARSGGAGGQNV 289
Cdd:TIGR00019 159 GGYKEVIAEIKGDGVYSRLKFESGVHRVQRVPVTESQGRIHTSAATVAVMPELEEVEVDINPADLRIDTFRSSGAGGQHV 238

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937940199  290 NKVETAVDLIHKPTGIRIFCTEERSQLQNRERAFQLLRAKLYEIKLREQQESIRNQRKLQVGTGARSEKIRTYNYKDNRV 369
Cdd:TIGR00019 239 NTTDSAVRITHLPTGIVVECQDERSQHKNKDKAMKVLRARLYEAEQEKQQAAQASTRKSQVGSGDRSERIRTYNFPQNRV 318

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|
gi 937940199  370 TDHRLKMN-FELTGFLMGDIESAVQSCSSMEQKELLEEMA 408
Cdd:TIGR00019 319 TDHRINLTlYKLDEVLEGDLDELIEALIAEDQAQQLAALS 358
PCRF pfam03462
PCRF domain; This domain is found in peptide chain release factors.
 62-256 1.08e-83

PCRF domain; This domain is found in peptide chain release factors.


Pssm-ID: 460929 [Multi-domain]  Cd Length: 192  Bit Score: 254.23  E-value: 1.08e-83
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937940199   62 EKAWKEMSVRLADPDIVSDPSEYQKLAQSVAELDQVVSTYRQFKDCEKQIEETKVLqkenEDDPDMAEMIDSEMESLSNQ 141
Cdd:pfam03462   2 EERYEELEALLSDPDVWDDQKRAQKLSKEYSELEPIVEAYREYKQALEDLEEAKEL----LEDPELAELAEEELEELEKR 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937940199  142 LEELEEKLKLLLLPNDPLDARNILLEVRAGAGGDEAGIWAGDLVRMYQKYCERNSWKFKPVSSSEAEKGGFKTYVMEVKG 221
Cdd:pfam03462  78 LEELEEELKLLLLPKDPNDDKNAILEIRAGAGGDEAALFAGDLFRMYTRYAERKGWKVEVLDYSETEAGGIKEATFEISG 157

                         170       180       190
                  ....*....|....*....|....*....|....*
gi 937940199  222 KQVYSKLKFESGVHRVQRVPQTETMGRVHTSTATV 256
Cdd:pfam03462 158 EGAYGRLKFESGVHRVQRVPPTESQGRIHTSFATV 192
PCRF smart00937
This domain is found in peptide chain release factors;
120-231 6.08e-40

This domain is found in peptide chain release factors;


Pssm-ID: 214923 [Multi-domain]  Cd Length: 116  Bit Score: 138.36  E-value: 6.08e-40
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937940199   120 ENEDDPDMAEMIDSEMESLSNQLEELEEKLKLLL-LPNDPLDARNILLEVRAGAGGDEAGIWAGDLVRMYQKYCERNSWK 198
Cdd:smart00937   4 EEEEDDEMRELAEEELEELEAELEEELEELLKLLlLPKDPNDDKNAILEIRAGAGGDEAALFAGDLLRMYLRYAERKGWK 83

                           90       100       110
                   ....*....|....*....|....*....|...
gi 937940199   199 FKPVSSSEAEKGGFKTYVMEVKGKQVYSKLKFE 231
Cdd:smart00937  84 VEVLDESEGELGGIKEATLKISGEGAYGKLKFE 116
 
Name Accession Description Interval E-value
PrfA COG0216
Protein chain release factor RF1 [Translation, ribosomal structure and biogenesis]; Protein ...
 53-408 0e+00

Protein chain release factor RF1 [Translation, ribosomal structure and biogenesis]; Protein chain release factor RF1 is part of the Pathway/BioSystem: Translation factors


Pssm-ID: 439986 [Multi-domain]  Cd Length: 356  Bit Score: 523.41  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937940199  53 YLIAKLDSAEKAWKEMSVRLADPDIVSDPSEYQKLAQSVAELDQVVSTYRQFKDCEKQIEETKVLQKEnEDDPDMAEMID 132
Cdd:COG0216    1 SMLDKLEALEERYEELEALLSDPEVISDQKRFRKLSKEYAELEPIVEAYREYKKLLEDIEEAKELLEE-ESDPEMREMAK 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937940199 133 SEMESLSNQLEELEEKLKLLLLPNDPLDARNILLEVRAGAGGDEAGIWAGDLVRMYQKYCERNSWKFKPVSSSEAEKGGF 212
Cdd:COG0216   80 EELEELEARLEELEEELKILLLPKDPNDDKNVILEIRAGTGGDEAALFAGDLFRMYSRYAERKGWKVEILSASEGELGGY 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937940199 213 KTYVMEVKGKQVYSKLKFESGVHRVQRVPQTETMGRVHTSTATVAIMPEADEVDVVIDPKDIELKTARSGGAGGQNVNKV 292
Cdd:COG0216  160 KEVIFRISGEGVYSRLKFESGVHRVQRVPETESQGRIHTSAATVAVLPEAEEVDVEINPKDLRIDTFRSSGAGGQHVNTT 239

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937940199 293 ETAVDLIHKPTGIRIFCTEERSQLQNRERAFQLLRAKLYEIKLREQQESIRNQRKLQVGTGARSEKIRTYNYKDNRVTDH 372
Cdd:COG0216  240 DSAVRITHLPTGIVVECQDERSQHKNKAKAMKVLRARLYEAEQQKQQAEIAAERKSQVGSGDRSERIRTYNFPQGRVTDH 319

                        330       340       350
                 ....*....|....*....|....*....|....*..
gi 937940199 373 RLKMNF-ELTGFLMGDIESAVQSCSSMEQKELLEEMA 408
Cdd:COG0216  320 RINLTLyKLDEVMEGDLDELIDALIAEDQAEKLAALE 356
prfA PRK00591
peptide chain release factor 1; Validated
 51-408 0e+00

peptide chain release factor 1; Validated


Pssm-ID: 234801 [Multi-domain]  Cd Length: 359  Bit Score: 522.33  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937940199  51 EPYLIAKLDSAEKAWKEMSVRLADPDIVSDPSEYQKLAQSVAELDQVVSTYRQFKDCEKQIEETKVLQKEnEDDPDMAEM 130
Cdd:PRK00591   1 KPSMLDKLEALEERYEELEALLSDPEVISDQKRFRKLSKEYAELEPIVEAYREYKQAQEDLEEAKEMLEE-ESDPEMREM 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937940199 131 IDSEMESLSNQLEELEEKLKLLLLPNDPLDARNILLEVRAGAGGDEAGIWAGDLVRMYQKYCERNSWKFKPVSSSEAEKG 210
Cdd:PRK00591  80 AKEELKELEERLEELEEELKILLLPKDPNDDKNVILEIRAGTGGDEAALFAGDLFRMYSRYAERQGWKVEILSASEGELG 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937940199 211 GFKTYVMEVKGKQVYSKLKFESGVHRVQRVPQTETMGRVHTSTATVAIMPEADEVDVVIDPKDIELKTARSGGAGGQNVN 290
Cdd:PRK00591 160 GYKEVIAEISGDGVYSKLKFESGVHRVQRVPATESQGRIHTSAATVAVLPEAEEVEVEINPKDLRIDTFRSSGAGGQHVN 239

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937940199 291 KVETAVDLIHKPTGIRIFCTEERSQLQNRERAFQLLRAKLYEIKLREQQESIRNQRKLQVGTGARSEKIRTYNYKDNRVT 370
Cdd:PRK00591 240 TTDSAVRITHLPTGIVVECQDERSQHKNKAKAMKVLRARLYDAERQKAQAEEAATRKSQVGSGDRSERIRTYNFPQGRVT 319

                        330       340       350
                 ....*....|....*....|....*....|....*....
gi 937940199 371 DHRLKM-NFELTGFLMGDIESAVQSCSSMEQKELLEEMA 408
Cdd:PRK00591 320 DHRINLtLYKLDEVMEGDLDELIDALIAEDQAEKLAALG 358
prfA TIGR00019
peptide chain release factor 1; This model describes peptide chain release factor 1 (PrfA, ...
 50-408 2.23e-154

peptide chain release factor 1; This model describes peptide chain release factor 1 (PrfA, RF-1), and excludes the related peptide chain release factor 2 (PrfB, RF-2). RF-1 helps recognize and terminate translation at UAA and UAG stop codons. The mitochondrial release factors are prfA-like, although not included above the trusted cutoff for this model. RF-1 does not have a translational frameshift. [Protein synthesis, Translation factors]


Pssm-ID: 129130 [Multi-domain]  Cd Length: 360  Bit Score: 440.67  E-value: 2.23e-154
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937940199   50 AEPYLIAKLDSAEKAWKEMSVRLADPDIVSDPSEYQKLAQSVAELDQVVSTYRQFKDCEKQIEETKVLQKENedDPDMAE 129
Cdd:TIGR00019   1 MKPSLLEKLESLLERYEELEALLSDPEVISDQDKLRKLSKEYSQLEEIVDCYREYQQAQEDIKEAKEILEES--DPEMRE 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937940199  130 MIDSEMESLSNQLEELEEKLKLLLLPNDPLDARNILLEVRAGAGGDEAGIWAGDLVRMYQKYCERNSWKFKPVSSSEAEK 209
Cdd:TIGR00019  79 MAKEELEELEEKIEELEEQLKVLLLPKDPNDEKNVILEIRAGTGGDEAAIFAGDLFRMYSRYAESKGWKVEILSANETEL 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937940199  210 GGFKTYVMEVKGKQVYSKLKFESGVHRVQRVPQTETMGRVHTSTATVAIMPEADEVDVVIDPKDIELKTARSGGAGGQNV 289
Cdd:TIGR00019 159 GGYKEVIAEIKGDGVYSRLKFESGVHRVQRVPVTESQGRIHTSAATVAVMPELEEVEVDINPADLRIDTFRSSGAGGQHV 238

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937940199  290 NKVETAVDLIHKPTGIRIFCTEERSQLQNRERAFQLLRAKLYEIKLREQQESIRNQRKLQVGTGARSEKIRTYNYKDNRV 369
Cdd:TIGR00019 239 NTTDSAVRITHLPTGIVVECQDERSQHKNKDKAMKVLRARLYEAEQEKQQAAQASTRKSQVGSGDRSERIRTYNFPQNRV 318

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|
gi 937940199  370 TDHRLKMN-FELTGFLMGDIESAVQSCSSMEQKELLEEMA 408
Cdd:TIGR00019 319 TDHRINLTlYKLDEVLEGDLDELIEALIAEDQAQQLAALS 358
PCRF pfam03462
PCRF domain; This domain is found in peptide chain release factors.
 62-256 1.08e-83

PCRF domain; This domain is found in peptide chain release factors.


Pssm-ID: 460929 [Multi-domain]  Cd Length: 192  Bit Score: 254.23  E-value: 1.08e-83
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937940199   62 EKAWKEMSVRLADPDIVSDPSEYQKLAQSVAELDQVVSTYRQFKDCEKQIEETKVLqkenEDDPDMAEMIDSEMESLSNQ 141
Cdd:pfam03462   2 EERYEELEALLSDPDVWDDQKRAQKLSKEYSELEPIVEAYREYKQALEDLEEAKEL----LEDPELAELAEEELEELEKR 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937940199  142 LEELEEKLKLLLLPNDPLDARNILLEVRAGAGGDEAGIWAGDLVRMYQKYCERNSWKFKPVSSSEAEKGGFKTYVMEVKG 221
Cdd:pfam03462  78 LEELEEELKLLLLPKDPNDDKNAILEIRAGAGGDEAALFAGDLFRMYTRYAERKGWKVEVLDYSETEAGGIKEATFEISG 157

                         170       180       190
                  ....*....|....*....|....*....|....*
gi 937940199  222 KQVYSKLKFESGVHRVQRVPQTETMGRVHTSTATV 256
Cdd:pfam03462 158 EGAYGRLKFESGVHRVQRVPPTESQGRIHTSFATV 192
prfB TIGR00020
peptide chain release factor 2; In many but not all taxa, there is a conserved real ...
 54-390 8.54e-69

peptide chain release factor 2; In many but not all taxa, there is a conserved real translational frameshift at a TGA codon. RF-2 helps terminate translation at TGA codons and can therefore regulate its own production by readthrough when RF-2 is insufficient. There is a Pfam model called "RF-1" for the superfamily of RF-1, RF-2, mitochondrial, RF-H, etc. [Protein synthesis, Translation factors]


Pssm-ID: 272858 [Multi-domain]  Cd Length: 364  Bit Score: 221.96  E-value: 8.54e-69
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937940199   54 LIAKLDSAEKAWKEMSVRLADPDIVSDPSEYQKLAQSVAELDQVVSTYRQFKDCEKQIEETKVLQKEnEDDPDMAEMIDS 133
Cdd:TIGR00020  21 GSLDPEKKKARLEELEKEMEDPNFWNDQERAQAVIKERSSLEAVLDTLEELKNSLEDLSELLELAVE-EDDEETFNELDA 99

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937940199  134 EMESLSNQLEELEEKLKLlllpNDPLDARNILLEVRAGAGGDEAGIWAGDLVRMYQKYCERNSWKFKPVSSSEAEKGGFK 213
Cdd:TIGR00020 100 ELKALEKKLAELELRTML----SGEYDANNAYLTIQAGAGGTEAQDWASMLYRMYLRWAERRGFKVEIIDYSEGEEAGIK 175

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937940199  214 TYVMEVKGKQVYSKLKFESGVHRVQRVPQTETMGRVHTSTATVAIMPEADE-VDVVIDPKDIELKTARSGGAGGQNVNKV 292
Cdd:TIGR00020 176 SVTILIKGPYAYGYLKSEQGVHRLVRISPFDANGRRHTSFASVFVMPEVDDdIDIEIKPEDLRIDTYRASGAGGQHVNKT 255

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937940199  293 ETAVDLIHKPTGIRIFCTEERSQLQNRERAFQLLRAKLYEIKLREQQESIRNQRKLQVGTGARSEkIRTYNYKD-NRVTD 371
Cdd:TIGR00020 256 DSAVRITHIPTGIVVQCQNDRSQHKNKDSAMKVLKAKLYELEMEKEQAEKDAKEGEKSEIGWGSQ-IRSYVLHPySMVKD 334

                         330
                  ....*....|....*....
gi 937940199  372 HRlkmnfelTGFLMGDIES 390
Cdd:TIGR00020 335 LR-------TGYETGNVQA 346
RF-1 pfam00472
RF-1 domain; This domain is found in peptide chain release factors such as RF-1 and RF-2, and ...
 263-373 1.25e-54

RF-1 domain; This domain is found in peptide chain release factors such as RF-1 and RF-2, and a number of smaller proteins of unknown function. This domain contains the peptidyl-tRNA hydrolase activity. The domain contains a highly conserved motif GGQ, where the glutamine is thought to coordinate the water that mediates the hydrolysis.


Pssm-ID: 459823 [Multi-domain]  Cd Length: 111  Bit Score: 176.46  E-value: 1.25e-54
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937940199  263 DEVDVVIDPKDIELKTARSGGAGGQNVNKVETAVDLIHKPTGIRIFCTEERSQLQNRERAFQLLRAKLYEIKLREQQESI 342
Cdd:pfam00472   1 DEIEIEIDPKDLRIDTFRSSGAGGQHVNKTDSAVRLTHIPTGIVVKCQDERSQHQNREKALKRLRARLYELEEEKEEEKK 80

                          90       100       110
                  ....*....|....*....|....*....|..
gi 937940199  343 RNQRKlQVGTGARSEKIRTYNYKD-NRVTDHR 373
Cdd:pfam00472  81 RRIKS-QVGSGDRSEQIRTYNFKPqSRVKDHR 111
PRK08787 PRK08787
peptide chain release factor 2; Provisional
 120-394 8.05e-52

peptide chain release factor 2; Provisional


Pssm-ID: 136970 [Multi-domain]  Cd Length: 313  Bit Score: 176.39  E-value: 8.05e-52
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937940199 120 ENEDDPDMAEMIDSEMESLSNQLEELEEKLKLlllpNDPLDARNILLEVRAGAGGDEAGIWAGDLVRMYQKYCERNSWKF 199
Cdd:PRK08787  27 ESEQDEDTALAVIADLDKYQAHVEKLEFQRMF----SGQMDGANAFVDIQAGAGGTEAQDWAEILLRMYLRWAESRGWKT 102

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937940199 200 KPVSSSEAEKGGFKTYVMEVKGKQVYSKLKFESGVHRVQRVPQTETMGRVHTSTATVAIMPEADE-VDVVIDPKDIELKT 278
Cdd:PRK08787 103 ELMEVSGGEVAGIKSATVRIEGEYAYGWLKTEIGVHRLVRKSPFDSDNRRHTSFTSVFVSPEVDDnIEIDINPADLRTDV 182

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937940199 279 ARSGGAGGQNVNKVETAVDLIHKPTGIRIFCTEERSQLQNRERAFQLLRAKLY--EIKLREQQESIRNQRKLQVGTGArs 356
Cdd:PRK08787 183 YRSSGAGGQHVNKTESAVRITHIPTNTVVACQTGRSQHQNRDNAMKMLAAKLYelEVQKRNAEKDALEATKSDIGWGS-- 260

                        250       260       270
                 ....*....|....*....|....*....|....*....
gi 937940199 357 eKIRTYNYKDNRVTDHRLKMNFELT-GFLMGDIESAVQS 394
Cdd:PRK08787 261 -QIRNYVLDQSRIKDLRTGIERSDTqKVLDGDLDEFVEA 298
PRK07342 PRK07342
peptide chain release factor 2; Provisional
 74-362 1.22e-51

peptide chain release factor 2; Provisional


Pssm-ID: 235997 [Multi-domain]  Cd Length: 339  Bit Score: 176.61  E-value: 1.22e-51
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937940199  74 DPDIVSDPSEYQKLAQSVAELDQVVSTYRQFkdcEKQIEETKVLQKENEDDPDMAEMIDSE--MESLSNQLEELEEKLKL 151
Cdd:PRK07342   5 DPSLWNDAQEAQKLMRERQQLDDSINGINHL---EQTLNDNIELIAMGEEEGDKSIVEDAEktIRDLKDEIDRRQIDALL 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937940199 152 LLLPndplDARNILLEVRAGAGGDEAGIWAGDLVRMYQKYCERNSWKFKPVSSSEAEKGGFKTYVMEVKGKQVYSKLKFE 231
Cdd:PRK07342  82 SGEA----DANDTYLEVHAGAGGTESQDWASMLLRMYTRWAERQGRKVEVLEVHDGEEAGIKSATILVKGHNAYGWLKTE 157

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937940199 232 SGVHRVQRVPQTETMGRVHTSTATVAIMPEADE-VDVVIDPKDIELKTARSGGAGGQNVNKVETAVDLIHKPTGIRIFCT 310
Cdd:PRK07342 158 SGVHRLVRISPYDSNARRHTSFASIWVYPVIDDnIEVDVNESDVRIDTYRSSGAGGQHVNTTDSAVRITHIPTGIVVQCQ 237

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....
gi 937940199 311 EERSQLQNRERAFQLLRAKLYEIKL--REQQESIRNQRKLQVGTGarsEKIRTY 362
Cdd:PRK07342 238 QERSQHKNRAKAWSMLRARLYEEELkkREEATNAAAASKTDIGWG---HQIRSY 288
PRK06746 PRK06746
peptide chain release factor 2; Provisional
 80-373 3.52e-51

peptide chain release factor 2; Provisional


Pssm-ID: 75726 [Multi-domain]  Cd Length: 326  Bit Score: 174.92  E-value: 3.52e-51
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937940199  80 DPSEYQKLAQSVAELDQVVSTYRQFKDCEKQIEETKVLQKEnEDDPDMAEMIDSEMESLSNQLEELEEKLKLlllpNDPL 159
Cdd:PRK06746   9 DQQGAQAVINEANALKDMVGKFRQLDETFENLEITHELLKE-EYDEDLHEELESEVKGLIQEMNEYELQLLL----SDPY 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937940199 160 DARNILLEVRAGAGGDEAGIWAGDLVRMYQKYCERNSWKFKPVSSSEAEKGGFKTYVMEVKGKQVYSKLKFESGVHRVQR 239
Cdd:PRK06746  84 DKNNAILELHPGAGGTESQDWGSMLLRMYTRWAEKRGFKVETVDYLPGDEAGIKSVTLLIKGHNAYGYLKAEKGVHRLVR 163

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937940199 240 VPQTETMGRVHTSTATVAIMPE-ADEVDVVIDPKDIELKTARSGGAGGQNVNKVETAVDLIHKPTGIRIFCTEERSQLQN 318
Cdd:PRK06746 164 ISPFDSSGRRHTSFVSCEVVPEfNDEVEIEVRTEDLKIDTYRASGAGGQHVNTTDSAVRITHTPTNTVVTCQSERSQIKN 243

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 937940199 319 RERAFQLLRAKLYEIKLREQQ---ESIRNQRKlQVGTGArseKIRTYNYKD-NRVTDHR 373
Cdd:PRK06746 244 REHAMKMLKAKLYQKKLEEQQaelDEIRGEQK-EIGWGS---QIRSYVFHPySLVKDHR 298
PRK05589 PRK05589
peptide chain release factor 2; Provisional
 74-389 1.15e-48

peptide chain release factor 2; Provisional


Pssm-ID: 235520 [Multi-domain]  Cd Length: 325  Bit Score: 168.06  E-value: 1.15e-48
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937940199  74 DPDIVSDPSEYQKLAQSVAELDQVVSTYRQFkdcEKQIEETKVLQK-ENEDDPDMAEMIDSEMESLSNQLEELEEKLKLL 152
Cdd:PRK05589   3 EPNFWNDIKEAQEITSEEKYLKDKLDKYNHL---RNRIEDIEVLCEmMSEEDDEMKKEIISEVKNIKEEIDRFKIETLLS 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937940199 153 LLpndpLDARNILLEVRAGAGGDEAGIWAGDLVRMYQKYCERNSWKFKPVSSSEAEKGGFKTYVMEVKGKQVYSKLKFES 232
Cdd:PRK05589  80 GE----YDRNNAILTLHSGVGGTDAQDWTEMLLRMYTRWAEKKGYKVEIIDLLEGDEAGIKSVTLKITGEFAYGYLKAEK 155

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937940199 233 GVHRVQRVPQTETMGRVHTSTATVAIMPE-ADEVDVVIDPKDIELKTARSGGAGGQNVNKVETAVDLIHKPTGIRIFCTE 311
Cdd:PRK05589 156 GIHRLVRISPFNANGKRQTSFASVEVLPElTDDQDIEIRSEDLKIDTYRAGGAGGQHVNKTESAVRITHIPTGIVVQCQN 235

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937940199 312 ERSQLQNRERAFQLLRAKLYEIKLREQQESIRN---QRKlQVGTGArseKIRTYNYKD-NRVTDHRLKM-NFELTGFLMG 386
Cdd:PRK05589 236 ERSQHSNKETAMKMLKSKLVELKERAHKEKIEDltgELK-DMGWGS---QIRSYVFHPyNLVKDHRTGVeTSNVDSVMDG 311


                 ...
gi 937940199 387 DIE 389
Cdd:PRK05589 312 DID 314
PCRF smart00937
This domain is found in peptide chain release factors;
120-231 6.08e-40

This domain is found in peptide chain release factors;


Pssm-ID: 214923 [Multi-domain]  Cd Length: 116  Bit Score: 138.36  E-value: 6.08e-40
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937940199   120 ENEDDPDMAEMIDSEMESLSNQLEELEEKLKLLL-LPNDPLDARNILLEVRAGAGGDEAGIWAGDLVRMYQKYCERNSWK 198
Cdd:smart00937   4 EEEEDDEMRELAEEELEELEAELEEELEELLKLLlLPKDPNDDKNAILEIRAGAGGDEAALFAGDLLRMYLRYAERKGWK 83

                           90       100       110
                   ....*....|....*....|....*....|...
gi 937940199   199 FKPVSSSEAEKGGFKTYVMEVKGKQVYSKLKFE 231
Cdd:smart00937  84 VEVLDESEGELGGIKEATLKISGEGAYGKLKFE 116
PrfB COG1186
Protein chain release factor PrfB [Translation, ribosomal structure and biogenesis]; Protein ...
 266-373 4.12e-30

Protein chain release factor PrfB [Translation, ribosomal structure and biogenesis]; Protein chain release factor PrfB is part of the Pathway/BioSystem: Translation factors


Pssm-ID: 440799 [Multi-domain]  Cd Length: 140  Bit Score: 113.30  E-value: 4.12e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937940199 266 DVVIDPKDIELKTARSGGAGGQNVNKVETAVDLIHK------------PTGIRIFCTEERSQLQNRERAFQLLRAKLYEI 333
Cdd:COG1186   20 EIEIPESDLRIDTYRASGAGGQNVNKVSSAVRLTHDiassslpdsrltPGGIVVKAQEERSQHQNREDALKRLKALLYEA 99

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|..
gi 937940199 334 KLREQQEsiRNQRKLQVGTGARSE--KIRtynykdNRVTDHR 373
Cdd:COG1186  100 ELEPKER--RATKPTRGSKKRRLWgkQIR------SMVKDLR 133
release_prfH TIGR03072
putative peptide chain release factor H; Members of this protein family are bacterial proteins ...
 271-366 2.79e-15

putative peptide chain release factor H; Members of this protein family are bacterial proteins homologous to peptide chain release factors 1 (RF-1, product of the prfA gene), and 2 (RF-2, product of the prfB gene). The member from Escherichia coli K-12, designated prfH, appears to be a pseudogene. This class I release factor is always found as the downstream gene of a two-gene operon. [Protein synthesis, Translation factors]


Pssm-ID: 213768  Cd Length: 200  Bit Score: 74.04  E-value: 2.79e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937940199  271 PKDIELKTARSGGAGGQNVNKVETAVDLIHKPTGIRIFCTEERSQLQNRERAFQLLRAKLYeiKLREQQESI-RNQRKLQ 349
Cdd:TIGR03072 105 EDEIRFETLRSSGPGGQHVNKTESAVRATHLASGISVKVQSERSQHANKRLATLLLAVRLA--DLQQEQAAAlRAERRTA 182

                          90
                  ....*....|....*..
gi 937940199  350 VGTGARSEKIRTYNYKD 366
Cdd:TIGR03072 183 HHQIERGNPVRVFKGEL 199
PRK09256 PRK09256
aminoacyl-tRNA hydrolase;
266-337 1.98e-13

aminoacyl-tRNA hydrolase;


Pssm-ID: 181730 [Multi-domain]  Cd Length: 138  Bit Score: 67.10  E-value: 1.98e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937940199 266 DVVIDPKDIELKTARSGGAGGQNVNKVETAVDLI---------------------HKPTG---IRIFCTEERSQLQNRER 321
Cdd:PRK09256   7 RLVIPENELEWRFIRASGPGGQNVNKVSTAVELRfdiaasslpefykerllalagHRITKdgvIVIKAQEFRSQERNRED 86

                         90
                 ....*....|....*.
gi 937940199 322 AfqllRAKLYEIkLRE 337
Cdd:PRK09256  87 A----LERLVAL-IRE 97
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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