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Conserved domains on  [gi|933504240|gb|ALG66373|]
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NADH dehydrogenase subunit 4L (mitochondrion) [Kuwayamaea brachyptera]

Protein Classification

NADH dehydrogenase subunit 4L( domain architecture ID 10009597)

NADH dehydrogenase subunit 4L is the core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (complex I) that is believed to belong to the minimal assembly required for catalysis

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ND4L MTH00162
NADH dehydrogenase subunit 4L; Provisional
 4-92 1.62e-20

NADH dehydrogenase subunit 4L; Provisional


:

Pssm-ID: 177218  Cd Length: 89  Bit Score: 77.89  E-value: 1.62e-20
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 933504240  4 IFNLMIMFLIMMGGVWVFCSKRKHLLATLLSLEFIVLSLFAMLVFLLHYMSCELYFSMIFLTYAVCEGALGLSILVSMIR 83
Cdd:MTH00162  1 MMMLLIFLFMFFSGLLVFLSKRKHLLLMLLSLEFMVLSLFFLLFLYLSFFNYELYFLLFFLTFSVCEGALGLSILVSMIR 80


                ....*....
gi 933504240 84 THGNDFFQT 92
Cdd:MTH00162 81 SHGNDYFSS 89
 
Name Accession Description Interval E-value
ND4L MTH00162
NADH dehydrogenase subunit 4L; Provisional
 4-92 1.62e-20

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177218  Cd Length: 89  Bit Score: 77.89  E-value: 1.62e-20
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 933504240  4 IFNLMIMFLIMMGGVWVFCSKRKHLLATLLSLEFIVLSLFAMLVFLLHYMSCELYFSMIFLTYAVCEGALGLSILVSMIR 83
Cdd:MTH00162  1 MMMLLIFLFMFFSGLLVFLSKRKHLLLMLLSLEFMVLSLFFLLFLYLSFFNYELYFLLFFLTFSVCEGALGLSILVSMIR 80


                ....*....
gi 933504240 84 THGNDFFQT 92
Cdd:MTH00162 81 SHGNDYFSS 89
Oxidored_q2 pfam00420
NADH-ubiquinone/plastoquinone oxidoreductase chain 4L;
2-98 4.23e-07

NADH-ubiquinone/plastoquinone oxidoreductase chain 4L;


Pssm-ID: 425672  Cd Length: 95  Bit Score: 44.09  E-value: 4.23e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 933504240   2 VMIFNLMIMFLIMMGGVWVfcskRKHLLATLLSLEFIVLSLFAMLVFLLHYMSCEL--YFSMIFLTYAVCEGALGLSILV 79
Cdd:pfam00420  1 AYLLLSGLLFLIGLYGLLL----RRNLLRVLLSLELMLNAVNLALVLFGRLTADPLpqALILTAIVIAAAEAAVGLALLV 76

                         90
                 ....*....|....*....
gi 933504240  80 SMIRTHGNDFFQTFSVLQC 98
Cdd:pfam00420 77 RIYRTHGTDDVDSLNLLKG 95
 
Name Accession Description Interval E-value
ND4L MTH00162
NADH dehydrogenase subunit 4L; Provisional
 4-92 1.62e-20

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177218  Cd Length: 89  Bit Score: 77.89  E-value: 1.62e-20
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 933504240  4 IFNLMIMFLIMMGGVWVFCSKRKHLLATLLSLEFIVLSLFAMLVFLLHYMSCELYFSMIFLTYAVCEGALGLSILVSMIR 83
Cdd:MTH00162  1 MMMLLIFLFMFFSGLLVFLSKRKHLLLMLLSLEFMVLSLFFLLFLYLSFFNYELYFLLFFLTFSVCEGALGLSILVSMIR 80


                ....*....
gi 933504240 84 THGNDFFQT 92
Cdd:MTH00162 81 SHGNDYFSS 89
ND4L MTH00188
NADH dehydrogenase subunit 4L; Provisional
 7-98 1.10e-12

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177237  Cd Length: 97  Bit Score: 58.45  E-value: 1.10e-12
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 933504240  7 LMIMFLIMMGGVWVFCSKRKHLLATLLSLEFIVLSLFAMLVFLLHYMSCELYFSMIFLTYAVCEGALGLSILVSMIRTHG 86
Cdd:MTH00188  6 ILVILLFVVLGLFTFLLNRKHLLMLLLSLEAIMLSLFWFLLVGLSYMEKELYLSLVLLTFAACEASVGLALLVSLIRSHG 85

                        90
                ....*....|..
gi 933504240 87 NDFFQTFSVLQC 98
Cdd:MTH00188 86 SDYVSSLNLIKC 97
ND4L MTH00149
NADH dehydrogenase subunit 4L; Provisional
 7-98 5.24e-12

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 214434  Cd Length: 97  Bit Score: 56.39  E-value: 5.24e-12
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 933504240  7 LMIMFLIMMGGVWVFCSKRKHLLATLLSLEFIVLSLFAMLVFLLHYMSCELYFSMIFLTYAVCEGALGLSILVSMIRTHG 86
Cdd:MTH00149  6 LLLSLFGFLMGVFALLFQYKHLLSILLSLEALMLSLLVMMFSSSGLISFSSYLFLIILTFGACEASLGLSLLVSLIRLHG 85

                        90
                ....*....|..
gi 933504240 87 NDFFQTFSVLQC 98
Cdd:MTH00149 86 NDYVSSLSSLKF 97
ND4L MTH00125
NADH dehydrogenase subunit 4L; Provisional
 1-98 3.23e-11

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177184  Cd Length: 98  Bit Score: 54.47  E-value: 3.23e-11
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 933504240  1 MVMIFNLMIMFLIMMGGvwvFCSKRKHLLATLLSLEFIVLSLFAMLVFLLHYMSCELYFSM--IFLTYAVCEGALGLSIL 78
Cdd:MTH00125  2 TPTHFSLYTAFMLSLLG---LSFHRTHLMSALLCLESMMLSLFIMLSLWPITTQTPSFTPMpiILLTFSACEAGTGLALL 78

                        90       100
                ....*....|....*....|
gi 933504240 79 VSMIRTHGNDFFQTFSVLQC 98
Cdd:MTH00125 79 VATTRTHGSDHLKNLNLLQC 98
ND4L MTH00067
NADH dehydrogenase subunit 4L; Provisional
 1-98 2.62e-10

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177139  Cd Length: 98  Bit Score: 52.30  E-value: 2.62e-10
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 933504240  1 MVMIFNLMIMFLIMMGGvwvFCSKRKHLLATLLSLEFIVLSLFAMLVFLLHYMSCELYFS--MIFLTYAVCEGALGLSIL 78
Cdd:MTH00067  2 SPTYFTFYSAFLLGLMG---LAFHRTHLLSALLCLEGMMLSLFIALSLWSTQFESLSYFSlpMFMLTFSACEASTGLALM 78

                        90       100
                ....*....|....*....|
gi 933504240 79 VSMIRTHGNDFFQTFSVLQC 98
Cdd:MTH00067 79 VATTRTHGTDHLKNLNLLQC 98
ND4L MTH00126
NADH dehydrogenase subunit 4L; Provisional
 25-98 6.46e-10

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177185  Cd Length: 98  Bit Score: 51.12  E-value: 6.46e-10
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 933504240 25 RKHLLATLLSLEFIVLSLF-AMLVFLLHYMSCELYFS-MIFLTYAVCEGALGLSILVSMIRTHGNDFFQTFSVLQC 98
Cdd:MTH00126 23 RTHLLSALLCLEGMMLSLFiALSLWALQLESTSFSAApMLLLAFSACEASAGLALLVATARTHGTDRLQNLNLLQC 98
ND4L MTH00107
NADH dehydrogenase subunit 4L; Provisional
 3-98 7.15e-09

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177169  Cd Length: 98  Bit Score: 48.39  E-value: 7.15e-09
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 933504240  3 MIFNLMIMFLIMMGGVWVFcskRKHLLATLLSLEFIVLSLFAM--LVFLLHYMSCELYFSMIFLTYAVCEGALGLSILVS 80
Cdd:MTH00107  4 IYMNIMLAFTISLLGLLMY---RSHLMSSLLCLEGMMLSLFIMatLTILNTHFTLASMMPIILLVFAACEAAVGLALLVM 80

                        90
                ....*....|....*...
gi 933504240 81 MIRTHGNDFFQTFSVLQC 98
Cdd:MTH00107 81 VSNTYGTDYVQNLNLLQC 98
ND4L MTH00013
NADH dehydrogenase subunit 4L; Validated
 7-98 1.43e-07

NADH dehydrogenase subunit 4L; Validated


Pssm-ID: 133655  Cd Length: 97  Bit Score: 45.13  E-value: 1.43e-07
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 933504240  7 LMIMFLIMMGGVWVFCSKRKHLLATLLSLEFIVLSLFAMLVFLLHYMSC-ELYFSMIFLTYAVCEGALGLSILVSMIRTH 85
Cdd:MTH00013  5 LFILSISPFISMFNLSLQRKHLLMSLLSLEAMILSLALFIPLSLMFANQvNGMLAIVLLTFGACEASLGLSLLVLMTRSY 84

                        90
                ....*....|...
gi 933504240 86 GNDFFQTFSVLQC 98
Cdd:MTH00013 85 GNDMLKSLTSNKC 97
Oxidored_q2 pfam00420
NADH-ubiquinone/plastoquinone oxidoreductase chain 4L;
2-98 4.23e-07

NADH-ubiquinone/plastoquinone oxidoreductase chain 4L;


Pssm-ID: 425672  Cd Length: 95  Bit Score: 44.09  E-value: 4.23e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 933504240   2 VMIFNLMIMFLIMMGGVWVfcskRKHLLATLLSLEFIVLSLFAMLVFLLHYMSCEL--YFSMIFLTYAVCEGALGLSILV 79
Cdd:pfam00420  1 AYLLLSGLLFLIGLYGLLL----RRNLLRVLLSLELMLNAVNLALVLFGRLTADPLpqALILTAIVIAAAEAAVGLALLV 76

                         90
                 ....*....|....*....
gi 933504240  80 SMIRTHGNDFFQTFSVLQC 98
Cdd:pfam00420 77 RIYRTHGTDDVDSLNLLKG 95
ND4L MTH00181
NADH dehydrogenase subunit 4L; Provisional
 3-96 3.81e-06

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 214450  Cd Length: 93  Bit Score: 41.47  E-value: 3.81e-06
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 933504240  3 MIFNLMIMFLIMMGGvwvFCSKRKHLLATLLSLEFIVLSLFA--MLVFLLHYMSCELYFSMIFLTYAVCEGALGLSILVS 80
Cdd:MTH00181  1 MMFVFISAFILLLLG---LSLYKTHLLSLLLCLEGMMLFLFLllALFSLLSSSSSMLMFGLILLTFSACEAVLGLSLLVA 77

                        90
                ....*....|....*.
gi 933504240 81 MIRTHGNDFFQTFSVL 96
Cdd:MTH00181 78 TNRTHGSDHLLKFNLL 93
ND4L MTH00043
NADH dehydrogenase subunit 4L; Validated
 3-97 1.09e-05

NADH dehydrogenase subunit 4L; Validated


Pssm-ID: 214410  Cd Length: 98  Bit Score: 40.29  E-value: 1.09e-05
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 933504240  3 MIFNLMIMFLIMMGGVWVFCSKRKHLLATLLSLEFIVLSLFAMLVF--LLHYMSCELYFSMIFLTYAVCEGALGLSILVS 80
Cdd:MTH00043  1 MNIILIIILSSFFLGLLGILINRLHLLSILLCLELLLISLFLNISIwsLNYGNFSNLSFSLLLLTLSACEASIGLSLMVL 80

                        90
                ....*....|....*..
gi 933504240 81 MIRTHGNDFFQTFSVLQ 97
Cdd:MTH00043 81 LSRNHNSDLVASLNLLQ 97
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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