|
Name |
Accession |
Description |
Interval |
E-value |
| AcrB |
COG0841 |
Multidrug efflux pump subunit AcrB [Defense mechanisms]; |
1-987 |
0e+00 |
|
Multidrug efflux pump subunit AcrB [Defense mechanisms];
Pssm-ID: 440603 [Multi-domain] Cd Length: 1015 Bit Score: 874.43 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931595540 1 MWLlARLSLANRSLIGLITLAVIGFGAFAVPSLKQQLFPSIQPPTAMIVSPYPGAAPDVVSSQVTEPIEAGLQGTEGLEK 80
Cdd:COG0841 1 MNL-SRFFIRRPVAAIVLSLLILLAGLLAYLRLPVEQFPDIDPPTVTVSTTYPGASPEEVESTVTTPIEEALNGVEGIKY 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931595540 81 LSSESAEGISSIVAQFKFGTDMDRAADRMQQAVNRLGTQLPKDV-RPTVTAGSTEDFPAVVLA-AGSTGDQQKLADQLAT 158
Cdd:COG0841 80 ITSTSSEGSSSITVEFELGTDIDEALVDVQNAVDRARSDLPEDVePPGVTKVNPSDFPVMVLAlSSDDLDELELSDYAER 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931595540 159 SAVPELKKIAGVRDVRVTGAAKETVTITVDYAKLAGAGVEPAALITALQSAGKPVPAGSLTEGNRTLTVQVGGQLASVDA 238
Cdd:COG0841 160 NIKDRLERVPGVGQVQIFGGREREIRIWLDPDKLAAYGLTLADVANAIRAQNVDVPAGRIGGGDREYTVRTNGRLKTPEE 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931595540 239 LRDMYL-AGQRQPVRLADVASVEPRLAAATSLTRTNGKPSLGISIMMTSDGNAVDISEAVRGKLSGIGTTV--GAELTVI 315
Cdd:COG0841 240 FENIVIrTNDGSVVRLGDVARVEDGAEDYRSIARLNGKPAVGLAIQKQPGANALEVADAVRAKLEELQASLpeGVELTIV 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931595540 316 FDQGPYIQEAVKGLTTEGLLGLVFAVVVILLFLLSVRSTLVTAVSIPLSVMVALLALWTGDLSLNLLTLGALTIAVGRVV 395
Cdd:COG0841 320 YDQSEFIRASIEEVVKTLLEAILLVVLVVFLFLRSWRATLIPAVAIPVSLIGTFAVMYLLGFSLNILTLFALVLAIGIVV 399
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931595540 396 DDSIVVLENIKRHLAYGEGKQRAVLDGVREVAGAVTASTLTTVAVFLPIAFVSGITGQLFSPFAVTVTVALLASLIVSLT 475
Cdd:COG0841 400 DDAIVVVENIERHMEEGLSPLEAAIKGAREVAGAVIASTLTLVAVFLPLAFMGGITGQLFRQFALTVAIALLISLFVALT 479
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931595540 476 IVPVLAYWFLKPPKAGTDIAAFREQAEAKERrgiLQRAYVPVIRFATRRRLTTLLVALAILVGTFGLLSNLNTNFLDDSG 555
Cdd:COG0841 480 LTPALCARLLKPHPKGKKGRFFRAFNRGFDR---LTRGYGRLLRWALRHRKLTLLVALALLALSVLLFGRLPTEFFPEED 556
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931595540 556 STSMTVSQKLPPGSSIAARDDAARKVEGALAAEQGIEAYQVTIGSEPGFGGevSSVNQFQVTLRK----GTDTKALQDRL 631
Cdd:COG0841 557 QGQIIVSVQLPPGTSLERTEAVVRQVEEILLEVPEVESVFSVVGFSGGGSG--SNSGTIFVTLKPwderDRSADEIIARL 634
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931595540 632 VSRFKGDTSA-GEVKAGGDGGGFGSSDVSVVVKAPNDEALRAATDQVLAKVKGVQGLAEVTNDLAVSAPRVQIDVNERAA 710
Cdd:COG0841 635 REKLAKIPGArVFVFQPPAGGLGSGAPIEVQLQGDDLEELAAAAEKLLAALRQIPGLVDVRSDLQLGKPELQLDIDREKA 714
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931595540 711 AAAGLSADTVGQLAGQAIAGFPVGEVSVAGKRQQIVLRS-GVAPKDVAAIRVMPLLTPTG-PVPLERIAKVETVDGPVVV 788
Cdd:COG0841 715 AALGVTVADVASTLRAALGGRYVNDFNRGGREYDVRVQApEEDRNSPEDLENLYVRTPDGeMVPLSSVATIEEGTGPSSI 794
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931595540 789 KRSESERSATVTAKPV-GKDLGTVNAELDTALKGLKLGGGATYAIGGVSADQQEAFGDLGLALLAAIVIVFAIMVATFRS 867
Cdd:COG0841 795 NRYNGQRSVTVSANLApGVSLGEALAAIEELAAELKLPPGVSIEFTGQAEEEQESFSSLGLAFLLALLLVYLVLAAQFES 874
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931595540 868 FVQPLILLVSIPFAATGAFGLLLATGTPLGLPAMIGLLMLVGIVVTNAIVLIDLVNQYRRQGMSIQDAVVEGGRRRLRPI 947
Cdd:COG0841 875 FIQPLIILLTVPLALIGALLGLLLTGTPLNIYSQIGLIMLIGIVVKNAILLVDFANQLREEGMSLREAILEAARLRLRPI 954
|
970 980 990 1000
....*....|....*....|....*....|....*....|
gi 931595540 948 LMTASATIFALAPMAFGvTGEGAFIGKPLALVVIGGLVSS 987
Cdd:COG0841 955 LMTSLATILGLLPLALG-TGAGAEFRQPLGIAVIGGLLFS 993
|
|
| ACR_tran |
pfam00873 |
AcrB/AcrD/AcrF family; Members of this family are integral membrane proteins. Some are ... |
4-987 |
0e+00 |
|
AcrB/AcrD/AcrF family; Members of this family are integral membrane proteins. Some are involved in drug resistance. AcrB cooperates with a membrane fusion protein, AcrA, and an outer membrane channel TolC. The structure shows the AcrB forms a homotrimer.
Pssm-ID: 395701 [Multi-domain] Cd Length: 1021 Bit Score: 619.31 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931595540 4 LARLSLANRSLIGLITLAVIGFGAFAVPSLKQQLFPSIQPPTAMIVSPYPGAAPDVVSSQVTEPIEAGLQGTEGLEKLSS 83
Cdd:pfam00873 1 MSKFFIRRPIFTLVLAIAILLAGILSFFSLPVDAFPEIAPPTVQVSTSYPGASPEEVEDTVTQPIEQAMNGLDGLKYMSS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931595540 84 ESAEGISSIVAQFKFGTDMDRAADRMQQAVNRLGTQLPKDV-RPTVTAGSTEDFPAVVLAAGSTG---DQQKLADQLATS 159
Cdd:pfam00873 81 QSSYGLSSITLTFELGTDIDIARQDVQNRLQLATPLLPEGVqRPGISVIKTSLGPIMVLAVTSPDgsyTQTDLRDYADTN 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931595540 160 AVPELKKIAGVRDVRVTGAAKETVTITVDYAKLAGAGVEPAALITALQSAGKPVPAGSLTEGNRTLTVQVGGQLASVDAL 239
Cdd:pfam00873 161 IKPQLSRVPGVGDVQLFGGSEYAMRIWLDPQKLARYGLTLTDVVSALKEQNVNIGAGQLEGQGLQALIRAQGQLQSAEDF 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931595540 240 RDMYLAGQR-QPVRLADVASVEPRLAAATSLTRTNGKPSLGISIMMTSDGNAVDISEAVRGKLSGIGTTV--GAELTVIF 316
Cdd:pfam00873 241 EKIIVKNQDgSPVRLRDVATVELGSELYRGFATFNGKPAVGLGVQKLPGANAIETADAVRAKLAELKPTFpqGVEIVVVY 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931595540 317 DQGPYIQEAVKGLTTEGLLGLVFAVVVILLFLLSVRSTLVTAVSIPLSVMVALLALWTGDLSLNLLTLGALTIAVGRVVD 396
Cdd:pfam00873 321 DTTPFIRASIEEVVKTLLEAIVLVILVMFLFLQNWRATLIPAIAIPLSLLGTFAVMKAFGFSINTLTLGGLVLAIGLVVD 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931595540 397 DSIVVLENIKRHLA-YGEGKQRAVLDGVREVAGAVTASTLTTVAVFLPIAFVSGITGQLFSPFAVTVTVALLASLIVSLT 475
Cdd:pfam00873 401 DAIVVVENIERVLEeNGLKPLEAAYKSMGEIGGALVAIALVLSAVFLPILFLGGLTGRIFRQFAITIVLAILLSVLVALT 480
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931595540 476 IVPVLAYWFLKPPKAGTDIAAFREQAEAKERrgiLQRAYVPVIRFATRRRLTTLLVALAILVGTFGLLSNLNTNFLDDSG 555
Cdd:pfam00873 481 LTPALCATLLKPRREPKHGGFFRWFNRMFDR---LTRGYAKLLAKVLRHTAVVLLVALLLVVGSVWLFVRIPTEFLPEED 557
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931595540 556 STSMTVSQKLPPGSSIAARDDAARKVEGALAAEQGIEAYQVTIGSepGFGGEVSSVNQ--FQVTL-----RKGTD----- 623
Cdd:pfam00873 558 EGVFVTSAQLPPGVSLDQTQRVMKQVEKILKEKPEVESVFAVTGF--AFSGDNNGPNSgdAFISLkpwkeRPGPEksvqa 635
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931595540 624 -TKALQDRLVSRFKGDTSAGEVKAGGDGGGFGSSDVSVVVKAPND--EALRAATDQVLAKVKGVQGLAEVTNDLAVSAPR 700
Cdd:pfam00873 636 lIERLRKALKQIPGANVFLFQPIQLRGLGTISGFRSDLQVKIFGDdlDALDEARNQILAALAQLPGLSDVRSDGQEDQPQ 715
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931595540 701 VQIDVNERAAAAAGLSADTVGQLAGQAIAGFPVGEVSVAGKRQQIVLRSGVAPK-DVAAIRVMPLLTPTG-PVPLERIAK 778
Cdd:pfam00873 716 LQVNIDREKAARLGVSIQDINDTLSTALGGSYVNDFPEGGRVYDVVVQLPEDFRsSPEDIGQLYVRNPYGkMIPLSAFAK 795
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931595540 779 VETVDGPVVVKRSESERSATVTAKPV-GKDLGTVNAELDTALKGLKLGGGATYAIGGVSADQQEAFGDLGLALLAAIVIV 857
Cdd:pfam00873 796 IEWGYGPPSINRYNGFRSIVISGNVAaGDSLGDAMEAMAQIAKQVKLPPGYGYTWTGQFEQEQLAGNSLPILIALALLVV 875
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931595540 858 FAIMVATFRSFVQPLILLVSIPFAATGAFGLLLATGTPLGLPAMIGLLMLVGIVVTNAIVLIDLVNQYRRQ-GMSIQDAV 936
Cdd:pfam00873 876 FLVLAALYESWSDPLSIMLTVPLALVGALLALWLRGLPNSVYAQVGLILLIGLAVKNAILMVEFANELREQeGKSLEEAI 955
|
970 980 990 1000 1010
....*....|....*....|....*....|....*....|....*....|.
gi 931595540 937 VEGGRRRLRPILMTASATIFALAPMAFGvTGEGAFIGKPLALVVIGGLVSS 987
Cdd:pfam00873 956 LEACRLRLRPILMTALAAILGVLPLALS-TGAGSELQQPLGIVVFGGLVTS 1005
|
|
| CusA |
COG3696 |
Cu/Ag efflux pump CusA [Inorganic ion transport and metabolism]; |
6-987 |
0e+00 |
|
Cu/Ag efflux pump CusA [Inorganic ion transport and metabolism];
Pssm-ID: 442911 [Multi-domain] Cd Length: 1031 Bit Score: 566.96 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931595540 6 RLSLANRSLIGLITLAVIGFGAFAVPSLKQQLFPSIQPPTAMIVSPYPGAAPDVVSSQVTEPIEAGLQGTEGLEKLSSES 85
Cdd:COG3696 7 RFSLRNRLLVLLLTLLLAAAGIYSLRRLPIDAFPDITNVQVQVITEAPGLSPEEVEQQVTYPIETALNGLPGVKEVRSIS 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931595540 86 AEGISSIVAQFKFGTDMDRAadRmQQAVNRLGT---QLPKDVRPTVTAGST---EDFPAVVLAAGSTGDQQKLADQLATS 159
Cdd:COG3696 87 RFGLSVVTVIFEDGTDIYWA--R-QLVLERLQQvreQLPAGVTPELGPISTglgEIYQYTLESDPGKYSLMELRTLQDWV 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931595540 160 AVPELKKIAGVRDVRVTGAAKETVTITVDYAKLAGAGVEPAALITALQSAGKPVPAGSLTEGNRTLTVQVGGQLASVDAL 239
Cdd:COG3696 164 IRPQLRSVPGVAEVNSFGGFVKQYQVLVDPAKLRAYGLTLDDVIEALERNNANVGGGYIERGGQEYLVRGIGLIRSLEDI 243
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931595540 240 RDMYLAGQR-QPVRLADVASV----EPRLAAAtslTRTNGKPSLGISIMMTSDGNAVDISEAVRGKLSGIGTTV--GAEL 312
Cdd:COG3696 244 ENIVVKTRNgTPVLLRDVAEVrigpAPRRGAA---TLNGEGEVVGGIVLMLKGENALEVIEAVKAKLAELKPSLpeGVKI 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931595540 313 TVIFDQGPYIQEAVKGLTTEGLLGLVFAVVVILLFLLSVRSTLVTAVSIPLSVMVALLALWTGDLSLNLLTLGALTIAVG 392
Cdd:COG3696 321 VPFYDRSDLIDRAIHTVTKNLLEGALLVILVLFLFLGNLRAALIVALAIPLSLLFAFIVMRLFGISANLMSLGGLAIDFG 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931595540 393 RVVDDSIVVLENIKRHLA------YGEGKQRAVLDGVREVAGAVTASTLTTVAVFLPIAFVSGITGQLFSPFAVTVTVAL 466
Cdd:COG3696 401 IIVDGAVVMVENILRRLEenraagTPRERLEVVLEAAREVRRPIFFATLIIILVFLPIFTLEGVEGKLFRPMALTVIFAL 480
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931595540 467 LASLIVSLTIVPVLAYWFLKPPKAGTDIAAFReqaeakerrgILQRAYVPVIRFATRRRLTTLLVALAILVGTFGLLSNL 546
Cdd:COG3696 481 LGALLLSLTLVPVLASLLLRGKVPEKENPLVR----------WLKRLYRPLLRWALRHPKLVLAVALVLLVLALALFPRL 550
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931595540 547 NTNFLD--DSGSTSMTVSqkLPPGSSIAARDDAARKVEGALAAEQGIEAYQVTIGSePGFGGEVSSVNQFQVTL------ 618
Cdd:COG3696 551 GSEFLPelDEGDLLVMAT--LPPGISLEESVELGQQVERILKSFPEVESVVSRTGR-AEDATDPMGVNMSETFVilkprs 627
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931595540 619 --RKGTDTKALQDRL---VSRFKG--------------DTSAGeVKAggdgggfgssdvSVVVK--APNDEALRAATDQV 677
Cdd:COG3696 628 ewRSGRTKEELIAEMreaLEQIPGvnfnfsqpiqmrvdELLSG-VRA------------DVAVKifGDDLDVLRRLAEQI 694
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931595540 678 LAKVKGVQGLAEVTNDLAVSAPRVQIDVNERAAAAAGLSADTVGQLAGQAIAGFPVGEVSVAGKRQQIVLR-SGVAPKDV 756
Cdd:COG3696 695 EAVLKTVPGAADVQVERVTGLPQLDIRIDRDAAARYGLNVADVQDVVETAIGGKAVGQVYEGERRFDIVVRlPEELRDDP 774
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931595540 757 AAIRVMPLLTPTG-PVPLERIAKVETVDGPVVVKRSESERSATVTAKPVGKDLGTVNAELDTAL-KGLKLGGGATYAIGG 834
Cdd:COG3696 775 EAIRNLPIPTPSGaQVPLSQVADIEVVEGPNQISRENGRRRIVVQANVRGRDLGSFVAEAQAKVaEQVKLPPGYYIEWGG 854
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931595540 835 VSADQQEAFGDLGLALLAAIVIVFAIMVATFRSFVQPLILLVSIPFAATGAFGLLLATGTPLGLPAMIGLLMLVGIVVTN 914
Cdd:COG3696 855 QFENLQRATARLAIVVPLALLLIFLLLYLAFGSVRDALLILLNVPFALIGGVLALWLRGMPLSVSAGVGFIALFGVAVLN 934
|
970 980 990 1000 1010 1020 1030
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 931595540 915 AIVLIDLVNQYRRQGMSIQDAVVEGGRRRLRPILMTASATIFALAPMAFGvTGEGAFIGKPLALVVIGGLVSS 987
Cdd:COG3696 935 GVVLVSYINQLRAEGLDLREAIIEGALERLRPVLMTALVAALGLLPMALS-TGPGSEVQRPLATVVIGGLITS 1006
|
|
| RND_permease_2 |
NF033617 |
multidrug efflux RND transporter permease subunit; |
17-1004 |
4.22e-152 |
|
multidrug efflux RND transporter permease subunit;
Pssm-ID: 411236 [Multi-domain] Cd Length: 1009 Bit Score: 477.97 E-value: 4.22e-152
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931595540 17 LITLAVIGFGAFAVPSLKQQLFPSIQPPTAMIVSPYPGAAPDVVSSQVTEPIEAGLQGTEGLEKLSSESAEGISSIVAQF 96
Cdd:NF033617 13 LLSLLILLLGLLAFRKLPVREYPEVDFPTITVSTSYPGASPELMQSSITQPLEQQLAQIEGIDEMTSQSSLGYSTITLQF 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931595540 97 KFGTDMDRAADRMQQAVNRLGTQLPKDVR-PTVT--AGSTeDFPAVVLAAGSTG-DQQKLADQLATSAVPELKKIAGVRD 172
Cdd:NF033617 93 RLGTDLDVALSEVQAAINAAQSLLPSEAPdPPVYrkANSA-DTPIMYIGLTSEEmPRGQLTDYAERVLAPKLSQINGVGS 171
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931595540 173 VRVTGAAKETVTITVDYAKLAGAGVEPAALITALQSAGKPVPAGSLTEGNRTLTVQVGGQLASVDALRDMYLAGQRQ--P 250
Cdd:NF033617 172 VDVSGGQRPAMRVWLDPEKMAARGLTADDVRSALNSNNVNSPKGAVRGDSVVSTVRANDQLKTAEDYEDLVIKYADNgaP 251
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931595540 251 VRLADVASVEPRLAAATSLTRTNGKPSLGISIMMTSDGNAVDISEAVRGKLSGIGTTVGA--ELTVIFDQGPYIQEAVKG 328
Cdd:NF033617 252 VRLGDVATVELGAENVRNRAWANGVPAVVLGINRQPGANPIEVADEIRALLPELQETLPKniKVNVLYDRTRFIRASIDE 331
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931595540 329 LTTEGLLGLVFAVVVILLFLLSVRSTLVTAVSIPLSVMVALLALWTGDLSLNLLTLGALTIAVGRVVDDSIVVLENIKRH 408
Cdd:NF033617 332 VESTLLEAVALVILVVFLFLRNLRATLIPAVTVPLSLIGTFAVMYLFGFSINLLTLMALVLAIGLVVDDAIVVVENIHRH 411
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931595540 409 LAYGEGKQRAVLDGVREVAGAVTASTLTTVAVFLPIAFVSGITGQLFSPFAVTVTVALLASLIVSLTIVPVLAYWFLKpp 488
Cdd:NF033617 412 IEEGESPLEAALKGAREIGFTVIAMTLTLVAVYLPILFMGGLTGRLFREFAVTLAGAVIISGIVALTLTPMMCSRLLK-- 489
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931595540 489 kagtdiaafREQAEAKERRGI------LQRAYVPVIRFATRRRLTTLLVALAILVGTFGLLSNLNTNFL--DDSGSTSMT 560
Cdd:NF033617 490 ---------ANEKPGRFARAVdrffdgLTARYGRGLKWVLKHRPLTLVVALATLALLPLLYVFIPKELApsEDRGVIFGM 560
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931595540 561 VsqKLPPGSSIAARDDAARKVEGALAAEQGIEAYQVTIGsepgfGGEVSSVNQ--FQVTLRKGTDTKALQDRLVSRFKG- 637
Cdd:NF033617 561 I--QAPQSISLDYMSAKMRDVEKILSSDPEVQSLTSFNG-----VGGNPGDNTgfGIINLKPWDERDVSAQEIIDRLRPk 633
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931595540 638 -------DTSAGEVKAGGDGGGFGSSDVSVVVKAPNDEALRAATDQVLAKVKGVQGLAEVTNDLAVSAPRVQIDVNERAA 710
Cdd:NF033617 634 lakvpgmDLFLFPLQDLPGGAGSSLPQYQVTLTPSDYDSLFTWAEKLKEKLRKSPQFADVDSDLQDKGPELNVDIDRDKA 713
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931595540 711 AAAGLSADTVGQLAGQAIAGFPVGEVSVAGKRQQIVLRSGVAPK-DVAAIRVMPLLTPTGP-VPLERIAKVETVDGPVVV 788
Cdd:NF033617 714 ARLGISMQDIGSTLEVAFGQRQVNTIYTDGNQYKVVLEVDRRYRlNPEALNQIYVRSNDGKlVPLSTLAKIEERAAPLSL 793
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931595540 789 KRSESERSATVTAKPV-GKDLGTVNAELDTALKGLkLGGGATYAIGGVSADQQEAFGDLGLALLAAIVIVFAIMVATFRS 867
Cdd:NF033617 794 NHFNQFNSATLSFNLApGVSLGEAIEALDQAAKEL-LPSGISGSFQGAARAFQEEGSSLLFLFLLALAAIYLVLAIQYES 872
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931595540 868 FVQPLILLVSIPFAATGAFGLLLATGTPLGLPAMIGLLMLVGIVVTNAIVLIDLVNQYRR-QGMSIQDAVVEGGRRRLRP 946
Cdd:NF033617 873 FVDPLTILSTVPLAGCGALLALALGGQSMNIYAQIGLITLIGLVKKNGILMVEFANELQRhQGLSRREAIYQAAALRLRP 952
|
970 980 990 1000 1010
....*....|....*....|....*....|....*....|....*....|....*...
gi 931595540 947 ILMTASATIFALAPMAFGvTGEGAFIGKPLALVVIGGLVSSTLLTLVLVPTLYTMVER 1004
Cdd:NF033617 953 ILMTTLAMLLGAIPLMLS-TGAGAESRFPLGIVIVGGLGVGTLFTLFVLPVVYLLLAR 1009
|
|
| 2A0601 |
TIGR00914 |
heavy metal efflux pump, CzcA family; This model represents a family of H+/heavy metal cation ... |
6-1024 |
7.91e-111 |
|
heavy metal efflux pump, CzcA family; This model represents a family of H+/heavy metal cation antiporters. This family is one of several subfamilies within the scope of pfam00873. [Cellular processes, Detoxification, Transport and binding proteins, Cations and iron carrying compounds]
Pssm-ID: 129992 [Multi-domain] Cd Length: 1051 Bit Score: 368.70 E-value: 7.91e-111
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931595540 6 RLSLANRSLIGLITLAVIGFGAFAVPSLKQQLFPSIQPPTAMIVSPYPGAAPDVVSSQVTEPIEAGLQGTEGLEKLSSES 85
Cdd:TIGR00914 7 SFSVAQRWLVLLATLVMAILGIWSYNRLPIDAVPDITNVQVQINTSAPGYSPLEVEQRVTYPIETAMAGLPGLETTRSLS 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931595540 86 AEGISSIVAQFKFGTDMDRAADRMQQAVNRLGTQLPKDVRPTVTAGST----------EDFPAVVLAAGSTGDQQKLADQ 155
Cdd:TIGR00914 87 RYGLSQVTVIFKDGTDLYFARQLVNERLQQARDNLPEGVSPEMGPISTglgeiflytvEAEEGARKKDGGAYTLTDLRTI 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931595540 156 LATSAVPELKKIAGVRDVRVTGAAKETVTITVDYAKLAGAGVEPAALITALQSAGKPVPAGSLTEGNRTLTVQVGGQLAS 235
Cdd:TIGR00914 167 QDWIIRPQLRTVPGVAEVNSIGGYVKQFLVAPDPEKLAAYGLSLADVVNALERNNQNVGAGYIERRGEQYLVRAPGQVQS 246
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931595540 236 VDALRDMYLA-GQRQPVRLADVASV----EPRLAAATSltrtNGKPSLGISIMMTSDGNAVDISEAVRGKLSGIGTTV-- 308
Cdd:TIGR00914 247 MDDIRNIVIAtGEGVPIRIRDVARVqigkELRTGAATE----NGKEVVLGTVFMLIGENSRTVAQAVGDKLETINKTLpe 322
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931595540 309 GAELTVIFDQGPYIQEAVKGLTTEGLLGLVFAVVVILLFLLSVRSTLVTAVSIPLSVMVALLALWTGDLSLNLLTLGALt 388
Cdd:TIGR00914 323 GVEIVTTYDRSQLVDAAIATVKKNLLEGALLVIVILFLFLGNIRAALIAATVIPLSLLITFIGMVFQGISANLMSLGAL- 401
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931595540 389 iAVGRVVDDSIVVLENIKRHLA---YGEGKQ-------RAVLDGVREVAGAVTASTLTTVAVFLPIAFVSGITGQLFSPF 458
Cdd:TIGR00914 402 -DFGLIVDGAVVIVENAHRRLAeaqHHHGRQltlkerlHEVFAASREVRRPLIFGQLIITLVFLPIFTLTGVEGKMFHPM 480
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931595540 459 AVTVTVALLASLIVSLTIVPVLAYWFLkppkagtdiaafREQAEAKERRGI--LQRAYVPVIRFATRRRLTTLLVALAIL 536
Cdd:TIGR00914 481 AFTVVLALAGAMILSLTFVPAAVALFI------------RGKVAEKENRLMrvLKRRYEPLLERVLAWPAVVLGAAAVSI 548
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931595540 537 VGTFGLLSNLNTNFLDDSGSTSMTVSQKLPPGSSIAARDDAARKVEGALAAEQGIEAYQVTIG-------SEPGFGGEVS 609
Cdd:TIGR00914 549 VLVVWIASRVGGEFIPSLNEGDLAYQALRIPGTSLAQSVAMQQTLEKLIKSFPEVARVFAKTGtaeiatdPMPPNASDTY 628
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931595540 610 SVNQFQVTLRKGTDTKA-----LQDRLVS------------RFKGDTSAGEVKAggdgggfgssDVSVVVKAPNDEALRA 672
Cdd:TIGR00914 629 IILKPESQWPEGKKTKEdlieeIQEATVRipgnnyeftqpiQMRFNELISGVRS----------DVAVKVFGDDLDDLDA 698
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931595540 673 ATDQVLAKVKGVQGLAEVTNDLAVSAPRVQIDVNERAAAAAGLSADTVGQLAGQAIAGFPVGEVSVAGKRQQIVLR-SGV 751
Cdd:TIGR00914 699 TAEKISAVLKGVPGAADVKVEQTTGLPYLTVEIDREKAARYGLTVGDVQDTVATAVGGRMSGETFEGDRRFDIVIRlPES 778
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931595540 752 APKDVAAIRVMPLLTPTGP------VPLERIAKVETVDGPVVVKRSESERSATVTAKPVGKDLGTVNAELDTAL-KGLKL 824
Cdd:TIGR00914 779 LRESPQALRQLPIPLPLSEdarkqfIPLSDVADLRVSPGPNQISRENGKRRVVVSANVRGRDLGSFVDDAKKAIaEQVKL 858
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931595540 825 GGGATYAIGGVSADQQEAFGDLGLALLAAIVIVFAIMVATFRSFVQPLILLVSIPFAATGAFGLLLATGTPLGLPAMIGL 904
Cdd:TIGR00914 859 PPGYWITWGGQFEQLQSATKRLQIVVPVTLLLIFVLLYAAFGNVKDALLVFTGIPFALTGGVFALWLRGIPLSISAAVGF 938
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931595540 905 LMLVGIVVTNAIVLIDLVNQYRRQGMSIQDAVVEGGRRRLRPILMTASATIFALAPMAFGvTGEGAFIGKPLALVVIGGL 984
Cdd:TIGR00914 939 IALSGVAVLNGLVMISFIRKLLEEGPSLDEAVYEGALTRVRPVLMTALVASLGFVPMAIA-TGTGAEVQRPLATVVIGGI 1017
|
1050 1060 1070 1080
....*....|....*....|....*....|....*....|
gi 931595540 985 VSSTLLTLVLVPTLYTMVERvkersrdKRAAKRSPSAPTE 1024
Cdd:TIGR00914 1018 ITATLLTLFVLPALYRLVHR-------RRHKGRKEHEPLE 1050
|
|
| 2A0602 |
TIGR00915 |
The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family; Proteins ... |
18-1017 |
2.44e-106 |
|
The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family; Proteins scoring above the trusted cutoff (1000) form a tight clade within the RND (Resistance-Nodulation-Cell Division) superfamily. Proteins scoring greater than the noise cutoff (100) appear to form a larger clade, cleanly separated from more distant homologs that include cadmium/zinc/cobalt resistance transporters. This family is one of several subfamilies within the scope of pfam00873. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Unknown substrate]
Pssm-ID: 273335 [Multi-domain] Cd Length: 1044 Bit Score: 356.35 E-value: 2.44e-106
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931595540 18 ITLAVIGFGAFAVPSLKQQLFPSIQPPTAMIVSPYPGAAPDVVSSQVTEPIEAGLQGTEGLEKLSSESA-EGISSIVAQF 96
Cdd:TIGR00915 15 IAIIIMLAGTLSILSLPVSQYPSIAPPAITVSASYPGASAQTVQDTVTQVIEQNMNGIDGLRYMSSSSDsDGSMTITLTF 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931595540 97 KFGTDMDRAADRMQQAVNRLGTQLPKDVRP---TVTAGSTEDFPAVVLAAGSTG-DQQKLADQLATSAVPELKKIAGVRD 172
Cdd:TIGR00915 95 EQGTDPDIAQVQVQNKLQLATPLLPQEVQRqgvRVEKASSNFLMVIGLVSDDGSmTKEDLSDYAASNMVDPLSRLEGVGD 174
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931595540 173 VRVTGAaKETVTITVDYAKLAGAGVEPAALITALQSAGKPVPAGSL--------TEGNRTLTVQvgGQLASVDALRDMYL 244
Cdd:TIGR00915 175 VQLFGS-QYAMRIWLDPAKLNSYQLTPADVISAISAQNAQISAGQLgglpavpgQQLNATIIAQ--TRLQTPEQFENILL 251
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931595540 245 -AGQR-QPVRLADVASVEPRLAAATSLTRTNGKPSLGISIMMTSDGNAVDISEAVRGKLSGIGTTV--GAELTVIFDQGP 320
Cdd:TIGR00915 252 kVNTDgSQVRLKDVARVELGGENYSISARFNGKPASGLAIKLATGANALDTAKAVKAELAVLEPFFpqGMKYVYPYDTTP 331
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931595540 321 YIQEAVKGLTTEGLLGLVFAVVVILLFLLSVRSTLVTAVSIPLSVMVALLALWTGDLSLNLLTLGALTIAVGRVVDDSIV 400
Cdd:TIGR00915 332 FVEASIEEVVHTLIEAIVLVFLVMYLFLQNFRATLIPTIAVPVVLLGTFAVLAAFGFSINTLTMFAMVLAIGLLVDDAIV 411
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931595540 401 VLENIKRHLA-YGEGKQRAVLDGVREVAGAVTASTLTTVAVFLPIAFVSGITGQLFSPFAVTVTVALLASLIVSLTIVPV 479
Cdd:TIGR00915 412 VVENVERVMAeEGLPPKEATRKSMGQIQGALVGIAMVLSAVFVPMAFFGGSTGAIYRQFSITIVSAMALSVLVALILTPA 491
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931595540 480 LAYWFLKPPKAGtdiaafrEQAEAKER--------RGILQRAYVPVIRFATRRRLTTLLVALAILVGTFGLLSNLNTNFL 551
Cdd:TIGR00915 492 LCATMLKPIEKG-------EHHEKKGGffgwfnrmFDSSTHGYENGVGKILRRRGRYLLVYVLLVGGMVFLFVRLPTSFL 564
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931595540 552 DDSGSTSMTVSQKLPPGSSIAARDDAARKVEGALAAEQGIEAYQVTIGSEPGFGGEVSSVNQFQVTLR-------KGTDT 624
Cdd:TIGR00915 565 PDEDQGVFMTIVQLPAGATAERTQAVLAQVTKYLLAKEKANVESVFTVNGFSFAGRGQNMGMAFIRLKdweertgKENSV 644
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931595540 625 KALQDRLVSRFKG--DTSAGEVKAGGDGGGFGSSDVSVVVKAPND---EALRAATDQVLAKVKGVQGLAEVTNDLAVSAP 699
Cdd:TIGR00915 645 FAIAGRATGHFMQikDAMVIAFVPPAILELGNATGFDFFLQDRAGlghEALLQARNQLLGLAAQNPALTRVRPNGLEDEP 724
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931595540 700 RVQIDVNERAAAAAGLSADTVGQLAGQAIAGFPVGEVSVAGKRQQIVLRSG----VAPKDVAAIRVMPllTPTGPVPLER 775
Cdd:TIGR00915 725 QLKIDIDREKAQALGVSIADINTTLSTAWGSSYVNDFIDRGRVKRVYVQAEedarMSPEDINKWYVRN--ASGEMVPFSA 802
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931595540 776 IAKVETVDGPVVVKRSESERSATVTAKPV-GKDLGTVNAELDTALKglKLGGGATYAIGGVSADQQEAfGDLGLALLA-A 853
Cdd:TIGR00915 803 FATVRWEYGSPQLERYNGLPSMEILGSAApGVSTGQAMAAMEAIAQ--KLPPGFGFSWTGMSYEERLS-GSQAPALYAlS 879
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931595540 854 IVIVFAIMVATFRSFVQPLILLVSIPFAATGAfglLLAT---GTPLGLPAMIGLLMLVGIVVTNAIVLIDLVNQYRRQGM 930
Cdd:TIGR00915 880 LLVVFLCLAALYESWSIPVSVMLVVPLGIIGA---LLATtlrGLSNDVYFQVGLLTTIGLSAKNAILIVEFAKELMAQGK 956
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931595540 931 SIQDAVVEGGRRRLRPILMTASATIFALAPMAFGvTGEGAFIGKPLALVVIGGLVSSTLLTLVLVPTLYTMVERV-KERS 1009
Cdd:TIGR00915 957 SIVEAALEAARLRLRPILMTSLAFILGVVPLAIS-TGAGSGSQHAIGTGVFGGMVTATVLAIFFVPLFYVVVRRLfKRKA 1035
|
....*...
gi 931595540 1010 RDKRAAKR 1017
Cdd:TIGR00915 1036 HEKEMSVE 1043
|
|
| PRK10614 |
PRK10614 |
multidrug efflux system subunit MdtC; Provisional |
18-1015 |
2.25e-92 |
|
multidrug efflux system subunit MdtC; Provisional
Pssm-ID: 182589 [Multi-domain] Cd Length: 1025 Bit Score: 317.44 E-value: 2.25e-92
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931595540 18 ITLA-VIGFGAFAVPSLKQQLFPSIqpptaMIVSPYPGAAPDVVSSQVTEPIEAGLQGTEGLEKLSSESAEGISSIVAQF 96
Cdd:PRK10614 21 ITLCgILGFRLLPVAPLPQVDFPVI-----MVSASLPGASPETMASSVATPLERSLGRIAGVNEMTSSSSLGSTRIILQF 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931595540 97 KFGTDMDRAADRMQQAVNRLGTQLPKDV--RPTVTAGSTEDFPAVVLAAGS-TGDQQKLADQLATSAVPELKKIAGVRDV 173
Cdd:PRK10614 96 DFDRDINGAARDVQAAINAAQSLLPSGMpsRPTYRKANPSDAPIMILTLTSdTYSQGQLYDFASTQLAQTISQIDGVGDV 175
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931595540 174 RVTGAAKETVTITVDYAKLAGAGVEPAALITALQSAGKPVPAGSLTEGNRTLTVQVGGQLASVDALRDM---YLAGQrqP 250
Cdd:PRK10614 176 DVGGSSLPAVRVGLNPQALFNQGVSLDDVRQAISNANVRRPQGAVEDGTHRWQIQTNDELKTAAEYQPLiihYNNGA--A 253
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931595540 251 VRLADVASVEPRLAAATSLTRTNGKPSLGISIMMTSDGNAVDISEAVRGKLSGIGTTVGA--ELTVIFDQGPYIQEAVKG 328
Cdd:PRK10614 254 VRLGDVATVTDSVQDVRNAGMTNAKPAILLMIRKLPEANIIQTVDRIRAKLPELRETIPAaiDLQIAQDRSPTIRASLEE 333
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931595540 329 LTTEGLLGLVFAVVVILLFLLSVRSTLVTAVSIPLSVMVALLALWTGDLSLNLLTLGALTIAVGRVVDDSIVVLENIKRH 408
Cdd:PRK10614 334 VEQTLAISVALVILVVFLFLRSGRATLIPAVAVPVSLIGTFAAMYLCGFSLNNLSLMALTIATGFVVDDAIVVLENISRH 413
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931595540 409 LAYGEGKQRAVLDGVREVAGAVTASTLTTVAVFLPIAFVSGITGQLFSPFAVTVTVALLASLIVSLTIVPVLAYWFLK-- 486
Cdd:PRK10614 414 LEAGMKPLQAALQGVREVGFTVLSMSLSLVAVFLPLLLMGGLPGRLFREFAVTLSVAIGISLLVSLTLTPMMCAWLLKss 493
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931595540 487 PPKAGTDIAAFREQAEAkerrgiLQRAYVPVIRFATRRRLTTLLVALAILVGTFGLLSNLNTNFL--DDSGstsmtvsqk 564
Cdd:PRK10614 494 KPREQKRLRGFGRMLVA------LQQGYGRSLKWVLNHTRWVGVVLLGTIALNVWLYISIPKTFFpeQDTG--------- 558
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931595540 565 lppgssiaarddaarKVEGALAAEQGI---------EAYQVTIGSEP------GF--GGEVSSVNQFqVTLR----KGTD 623
Cdd:PRK10614 559 ---------------RLMGFIQADQSIsfqamrgklQDFMKIIRDDPavdnvtGFtgGSRVNSGMMF-ITLKplseRSET 622
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931595540 624 TKALQDRLVSRFKGDTSAG----EVKAGGDGGGFGSSDVSVVVKAPNDEALRAATDQVLAKVKGVQGLAEVTNDLAVSAP 699
Cdd:PRK10614 623 AQQVIDRLRVKLAKEPGANlflmAVQDIRVGGRQSNASYQYTLLSDDLAALREWEPKIRKALAALPELADVNSDQQDKGA 702
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931595540 700 RVQIDVNERAAAAAGLSADTVGQLAGQAIAGFPVGEVSVAGKRQQIVLrsGVAPK---DVAAIRVMPLLTPTG-PVPLER 775
Cdd:PRK10614 703 EMALTYDRDTMARLGIDVQAANSLLNNAFGQRQISTIYQPLNQYKVVM--EVDPRytqDISALEKMFVINNEGkAIPLSY 780
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931595540 776 IAKVETVDGPVVVKRSESERSATVTAK-PVGKDLGTVNAELDTALKGLKLGGGATYAIGGVSADQQEAFGDLGLALLAAI 854
Cdd:PRK10614 781 FAKWQPANAPLSVNHQGLSAASTISFNlPTGKSLSDASAAIERAMTQLGVPSTVRGSFAGTAQVFQETMNSQLILILAAI 860
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931595540 855 VIVFAIMVATFRSFVQPLILLVSIPFAATGAFGLLLATGTPLGLPAMIGLLMLVGIVVTNAIVLIDLVNQYRRQG-MSIQ 933
Cdd:PRK10614 861 ATVYIVLGILYESYVHPLTILSTLPSAGVGALLALELFNAPFSLIALIGIMLLIGIVKKNAIMMVDFALEAQRNGnLTAQ 940
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931595540 934 DAVVEGGRRRLRPILMTASATIFALAPMAFGvTGEGAFIGKPLALVVIGGLVSSTLLTLVLVPTLYTMVERVKERSRDKR 1013
Cdd:PRK10614 941 EAIFQACLLRFRPIMMTTLAALFGALPLVLS-GGDGAELRQPLGITIVGGLVMSQLLTLYTTPVVYLFFDRLRLRFSRKP 1019
|
..
gi 931595540 1014 AA 1015
Cdd:PRK10614 1020 KQ 1021
|
|
| PRK10503 |
PRK10503 |
MdtB/MuxB family multidrug efflux RND transporter permease subunit; |
14-1020 |
6.85e-91 |
|
MdtB/MuxB family multidrug efflux RND transporter permease subunit;
Pssm-ID: 182501 [Multi-domain] Cd Length: 1040 Bit Score: 313.59 E-value: 6.85e-91
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931595540 14 LIGLITLAVIGFGAFAVPSLKQQLFPSIQpptamIVSPYPGAAPDVVSSQVTEPIEAGLQGTEGLEKLSSESAEGISSIV 93
Cdd:PRK10503 27 MVAILLAGIIGYRALPVSALPEVDYPTIQ-----VVTLYPGASPDVMTSAVTAPLERQFGQMSGLKQMSSQSSGGASVIT 101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931595540 94 AQFKFGTDMDRAADRMQQAVNRLGTQLPKDV--RPTVTAGSTEDFPAVVLAAGSTG-DQQKLADQLATSAVPELKKIAGV 170
Cdd:PRK10503 102 LQFQLTLPLDVAEQEVQAAINAATNLLPSDLpnPPVYSKVNPADPPIMTLAVTSTAmPMTQVEDMVETRVAQKISQVSGV 181
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931595540 171 RDVRVTGAAKETVTITVDYAKLAGAGVEPAALITALQSAGKPVPAGSLTEGNRTLTVQVGGQLASVDALRDMYLAGQR-Q 249
Cdd:PRK10503 182 GLVTLSGGQRPAVRVKLNAQAIAALGLTSETVRTAITGANVNSAKGSLDGPTRAVTLSANDQMQSAEEYRQLIIAYQNgA 261
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931595540 250 PVRLADVASVEpRLAAATSLTR-TNGKPSLGISIMMTSDGNAVDISEAVRGKLSGIGTTV--GAELTVIFDQGPYIQEAV 326
Cdd:PRK10503 262 PIRLGDVATVE-QGAENSWLGAwANKQQAIVMNVQRQPGANIIATADSIRQMLPQLTESLpkSVKVTVLSDRTTNIRASV 340
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931595540 327 KGLTTEGLLGLVFAVVVILLFLLSVRSTLVTAVSIPLSVMVALLALWTGDLSLNLLTLGALTIAVGRVVDDSIVVLENIK 406
Cdd:PRK10503 341 DDTQFELMLAIALVVMIIYLFLRNIPATIIPGVAVPLSLIGTFAVMVFLDFSINNLTLMALTIATGFVVDDAIVVIENIS 420
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931595540 407 RHLAYGEGKQRAVLDGVREVAGAVTASTLTTVAVFLPIAFVSGITGQLFSPFAVTVTVALLASLIVSLTIVPVLAYWFLK 486
Cdd:PRK10503 421 RYIEKGEKPLAAALKGAGEIGFTIISLTFSLIAVLIPLLFMGDIVGRLFREFAVTLAVAILISAVVSLTLTPMMCARMLS 500
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931595540 487 PpkagtdiAAFREQ---AEAKERrgILQR---AYVPVIRFATRRRLTTLLVALAILVGTFGLLSNLNTNF--LDDSGSTS 558
Cdd:PRK10503 501 Q-------ESLRKQnrfSRASER--MFDRviaAYGRGLAKVLNHPWLTLSVALSTLLLTVLLWIFIPKGFfpVQDNGIIQ 571
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931595540 559 MTVsqKLPPGSSIAARDDAARKVEGALAAEQGIEAYQVTIGSEpgfgGEVSSVN--QFQVTLRKGTDTKALQDRLVSRFK 636
Cdd:PRK10503 572 GTL--QAPQSSSFANMAQRQRQVADVILQDPAVQSLTSFVGVD----GTNPSLNsaRLQINLKPLDERDDRVQKVIARLQ 645
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931595540 637 GDTSA--------GEVKAGGDGGGFGSSDVSVVVKAPNDEALRAATDQVLAKVKGVQGLAEVTNDLAVSAPRVQIDVNER 708
Cdd:PRK10503 646 TAVAKvpgvdlylQPTQDLTIDTQVSRTQYQFTLQATSLDALSTWVPKLMEKLQQLPQLSDVSSDWQDKGLVAYVNVDRD 725
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931595540 709 AAAAAGLSADTVGQLAGQAIAGFPVGEVSVAGKRQQIVLRSGVAPKD-VAAIRVMPLLTPTGP-VPLERIAKVETVDGPV 786
Cdd:PRK10503 726 SASRLGISMADVDNALYNAFGQRLISTIYTQANQYRVVLEHNTENTPgLAALDTIRLTSSDGGvVPLSSIATIEQRFGPL 805
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931595540 787 VVKRSESERSATVTAK-PVGKDLGTVNAELDTALKGLKLGGGATYAIGGVSADQQEAFGDLGLALLAAIVIVFAIMVATF 865
Cdd:PRK10503 806 SINHLDQFPSTTISFNvPDGYSLGDAVQAIMDTEKTLNLPADITTQFQGSTLAFQSALGSTVWLIVAAVVAMYIVLGVLY 885
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931595540 866 RSFVQPLILLVSIPFAATGAFGLLLATGTPLGLPAMIGLLMLVGIVVTNAIVLIDL-VNQYRRQGMSIQDAVVEGGRRRL 944
Cdd:PRK10503 886 ESFIHPITILSTLPTAGVGALLALMIAGSELDVIAIIGIILLIGIVKKNAIMMIDFaLAAEREQGMSPRDAIYQACLLRF 965
|
970 980 990 1000 1010 1020 1030
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 931595540 945 RPILMTASATIFALAPMAFGvTGEGAFIGKPLALVVIGGLVSSTLLTLVLVPTLYTMVERVKERSRDKRAAKRSPS 1020
Cdd:PRK10503 966 RPILMTTLAALLGALPLMLS-TGVGAELRRPLGICMVGGLIVSQVLTLFTTPVIYLLFDRLALYTKSRFPRHEEEA 1040
|
|
| PRK10555 |
PRK10555 |
multidrug efflux RND transporter permease AcrD; |
26-1010 |
1.37e-76 |
|
multidrug efflux RND transporter permease AcrD;
Pssm-ID: 182544 [Multi-domain] Cd Length: 1037 Bit Score: 272.86 E-value: 1.37e-76
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931595540 26 GAFAVPSLKQQLFPSIQPPTAMIVSPYPGAAPDVVSSQVTEPIEAGLQGTEGLEKLSSES-AEGISSIVAQFKFGTDMDR 104
Cdd:PRK10555 23 GTLAIFSLPVEQYPDLAPPNVRITANYPGASAQTLENTVTQVIEQNMTGLDNLMYMSSQSsGTGQASVTLSFKAGTDPDE 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931595540 105 AadrMQQAVNRLGT---QLPKDVRPT-VTAGSTEDFPAVVLAAGSTG---DQQKLADQLATSAVPELKKIAGVRDVRVTG 177
Cdd:PRK10555 103 A---VQQVQNQLQSamrKLPQAVQNQgVTVRKTGDTNILTIAFVSTDgsmDKQDIADYVASNIQDPLSRVNGVGDIDAYG 179
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931595540 178 AaKETVTITVDYAKLAGAGVEPAALITALQSAGKPVPAGSL----TEGNRTL--TVQVGGQLASVDALRDMYLAGQR--Q 249
Cdd:PRK10555 180 S-QYSMRIWLDPAKLNSFQMTTKDVTDAIESQNAQIAVGQLggtpSVDKQALnaTINAQSLLQTPEQFRDITLRVNQdgS 258
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931595540 250 PVRLADVASVEPRLAAATSLTRTNGKPSLGISIMMTSDGNAVDISEAVRGKLSGIGTTV--GAELTVIFDQGPYIQEAVK 327
Cdd:PRK10555 259 EVTLGDVATVELGAEKYDYLSRFNGKPASGLGVKLASGANEMATAKLVLNRLDELAQYFphGLEYKVAYETTSFVKASIE 338
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931595540 328 GLTTEGLLGLVFAVVVILLFLLSVRSTLVTAVSIPLSVMVALLALWTGDLSLNLLTLGALTIAVGRVVDDSIVVLENIKR 407
Cdd:PRK10555 339 DVVKTLLEAIALVFLVMYLFLQNFRATLIPTIAVPVVLMGTFSVLYAFGYSINTLTMFAMVLAIGLLVDDAIVVVENVER 418
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931595540 408 HLA-YGEGKQRAVLDGVREVAGAVTASTLTTVAVFLPIAFVSGITGQLFSPFAVTVTVALLASLIVSLTIVPVLAYWFLK 486
Cdd:PRK10555 419 IMSeEGLTPREATRKSMGQIQGALVGIAMVLSAVFVPMAFFGGTTGAIYRQFSITIVSAMVLSVLVAMILTPALCATLLK 498
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931595540 487 PPKAGtdiaafreqaEAKERRGILQRAYVPVIRFATR----------RRLTTLLVALAILVGTFGLLSNLNTNFLDDSGS 556
Cdd:PRK10555 499 PLKKG----------EHHGQKGFFGWFNRMFNRNAERyekgvakilhRSLRWILIYVLLLGGMVFLFLRLPTSFLPLEDR 568
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931595540 557 TSMTVSQKLPPGSSIAARDDAARKVEGALAAEQGIEAYQV--TIGSEPGFGGEvsSVNQFQVTL-----RKGTDTK--AL 627
Cdd:PRK10555 569 GMFTTSVQLPSGSTQQQTLKVVEKVEKYYFTHEKDNVMSVfaTVGSGPGGNGQ--NVARMFIRLkdwdeRDSKTGTsfAI 646
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931595540 628 QDRLVSRFKGDTSAGEVKAGGDGGGFGSSDVSVVVKAPND-----EALRAATDQVLAKVKGVQGLAEVTNDLAVSAPRVQ 702
Cdd:PRK10555 647 IERATKAFNKIKEARVIASSPPAISGLGSSAGFDMELQDHagaghDALMAARNQLLALAAKNPELTRVRHNGLDDSPQLQ 726
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931595540 703 IDVNERAAAAAGLSADTVGQLAGQAIAGFPVGEVSVAGKRQQIVLRSGVA----PKDVAAIRVMPllTPTGPVPLERIAK 778
Cdd:PRK10555 727 IDIDQRKAQALGVSIDDINDTLQTAWGSSYVNDFMDRGRVKKVYVQAAAPyrmlPDDINLWYVRN--KDGGMVPFSAFAT 804
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931595540 779 VETVDGPVVVKRSESERSATVTAKPV-GKDLGTVNAELDTALKGLKLGGGATYAigGVSAdQQEAFGDLGLALLA-AIVI 856
Cdd:PRK10555 805 SRWETGSPRLERYNGYSAVEIVGEAApGVSTGTAMDIMESLVKQLPNGFGLEWT--AMSY-QERLSGAQAPALYAiSLLV 881
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931595540 857 VFAIMVATFRSFVQPLILLVSIPFaatGAFGLLLAT---GTPLGLPAMIGLLMLVGIVVTNAIVLIDLVNQYRRQGMSIQ 933
Cdd:PRK10555 882 VFLCLAALYESWSVPFSVMLVVPL---GVIGALLATwmrGLENDVYFQVGLLTVIGLSAKNAILIVEFANEMNQKGHDLF 958
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931595540 934 DAVVEGGRRRLRPILMTASATIFALAPMAFGvTGEGAFIGKPLALVVIGGLVSSTLLTLVLVPTLYTMVER---VKERSR 1010
Cdd:PRK10555 959 EATLHASRQRLRPILMTSLAFIFGVLPMATS-TGAGSGSQHAVGTGVMGGMISATILAIFFVPLFFVLVRRrfpLKPRPE 1037
|
|
| PRK09579 |
PRK09579 |
multidrug efflux RND transporter permease subunit; |
20-984 |
8.01e-72 |
|
multidrug efflux RND transporter permease subunit;
Pssm-ID: 169983 [Multi-domain] Cd Length: 1017 Bit Score: 258.61 E-value: 8.01e-72
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931595540 20 LAVIGFGAFAVPSLKQqlFPSIQPPTAMIVSPYPGAAPDVVSSQVTEPIEAGLQGTEGLEKLSSESAEGISSIVAQFKFG 99
Cdd:PRK09579 21 IVLLGFQAWSKLQIRQ--YPQMENALITVTTAYPGANAETIQGYITQPLQQSLASAEGIDYMTSVSRQNFSIISIYARIG 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931595540 100 TDMDRAADRMQQAVNRLGTQLPKDVRPTVTAGSTEDFPAVVLAAGSTGDQQ--KLADQLATSAVPELKKIAGVRDVRVTG 177
Cdd:PRK09579 99 ADSDRLFTELLAKANEVKNQLPQDAEDPVLSKEAADASALMYISFYSEEMSnpQITDYLSRVIQPKLATLPGMAEAEILG 178
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931595540 178 AAKETVTITVDYAKLAGAGVEPAALITALQSAGKPVPAGSLTEGNRTLTVQVGGQLASVDALRDMYL--AGQRQpVRLAD 255
Cdd:PRK09579 179 NQVFAMRLWLDPVKLAGFGLSAGDVTQAVRRYNFLSAAGEVKGEYVVTSINASTELKSAEAFAAIPVktSGDSR-VLLGD 257
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931595540 256 VASVEPRLAAATSLTRTNGKPSLGISIMMTSDGNAVDISEAVRGKLSGIGTTV--GAELTVIFDQGPYIQEAVKGLTTEG 333
Cdd:PRK09579 258 VARVEMGAENYDSISSFDGIPSVYIGIKATPSANPLDVIKEVRAIMPELESQLppNLKVSIAYDATLFIQASIDEVVKTL 337
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931595540 334 LLGLVFAVVVILLFLLSVRSTLVTAVSIPLSVMVALLALWTGDLSLNLLTLGALTIAVGRVVDDSIVVLENIKRHLAYGE 413
Cdd:PRK09579 338 GEAVLIVIVVVFLFLGALRSVLIPVVTIPLSMIGVLFFMQMMGYSINLLTLLAMVLAIGLVVDDAIVVVENIHRHIEEGK 417
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931595540 414 GKQRAVLDGVREVAGAVTASTLTTVAVFLPIAFVSGITGQLFSPFAVTVTVALLASLIVSLTIVPVLAYWFLKPPKAGTD 493
Cdd:PRK09579 418 SPFDAALEGAREIAMPVVSMTITLAAVYAPIGFLTGLTGALFKEFALTLAGAVIISGIVALTLSPMMCALLLRHEENPSG 497
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931595540 494 IAAFREQAEAKerrgiLQRAYVPVIRFATRRRLTTLLVALAILVGTFGLL----SNLNTNflDDSGSTSMTVSQKLPPG- 568
Cdd:PRK09579 498 LAHRLDRLFER-----LKQRYQRALHGTLNTRPVVLVFAVIVLALIPVLLkftqSELAPE--EDQGIIFMMSSSPQPANl 570
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931595540 569 SSIAARDDAARKVEGALAAEQGieAYQVTigsepGFGGEVSSVNQFQVTLRKGTDTKALQDRLVSRFKGDTSAG----EV 644
Cdd:PRK09579 571 DYLNAYTDEFTPIFKSFPEYYS--SFQIN-----GFNGVQSGIGGFLLKPWNERERTQMELLPLVQAKLEEIPGlqifGF 643
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931595540 645 KAGGDGGGFGSSDVSVVVKAPND-EALRAATDQVLAKVKGVQGLAEVTNDLAVSAPRVQIDVNERAAAAAGLSADTVGQL 723
Cdd:PRK09579 644 NLPSLPGTGEGLPFQFVINTANDyESLLQVAQRVKQRAQESGKFAFLDIDLAFDKPEVVVDIDRAKAAQMGVSMQDLGGT 723
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931595540 724 AGQAIAGFPVGEVSVAGKRQQIVLRSGVAPKDVAA-IRVMPLLTPTGP-VPLERIAKVETVDGPVVVKRSESERSATVTA 801
Cdd:PRK09579 724 LATLLGEGEINRFTIDGRSYKVIAQVERPYRDNPGwLNNYYVKNEQGQlLPLSTLITLSDRARPRQLNQFQQLNSAIISG 803
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931595540 802 KPV---GKDLGTVnaeLDTALKGLKLGGGATYAiGGVSADQQEA---FGDLGLALlaaiVIVFAIMVATFRSFVQPLILL 875
Cdd:PRK09579 804 FPIvsmGEAIETV---QQIAREEAPEGFAFDYA-GASRQYVQEGsalWVTFGLAL----AIIFLVLAAQFESFRDPLVIL 875
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931595540 876 VSIPFAATGAFGLLLATGTPLGLPAMIGLLMLVGIVVTNAIVLIDLVNQYRR-QGMSIQDAVVEGGRRRLRPILMTASAT 954
Cdd:PRK09579 876 VTVPLSICGALIPLFLGVSSMNIYTQVGLVTLIGLISKHGILIVEFANQLRHeQGLSRREAIEEAAAIRLRPVLMTTAAM 955
|
970 980 990
....*....|....*....|....*....|
gi 931595540 955 IFALAPMAFGvTGEGAFIGKPLALVVIGGL 984
Cdd:PRK09579 956 VFGMVPLILA-TGAGAVSRFDIGLVIATGM 984
|
|
| PRK09577 |
PRK09577 |
multidrug efflux RND transporter permease subunit; |
17-1010 |
4.38e-70 |
|
multidrug efflux RND transporter permease subunit;
Pssm-ID: 169981 [Multi-domain] Cd Length: 1032 Bit Score: 253.62 E-value: 4.38e-70
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931595540 17 LITLAVIGFGAFAVPSLKQQLFPSIQPPTAMIVSPYPGAAPDVVSSQVTEPIEAGLQGTEGLEKLSSESAEGISSIVAQF 96
Cdd:PRK09577 14 VISLFIMLGGIFAIRALPVAQYPDIAPPVVSIYATYPGASAQVVEESVTALIEREMNGAPGLLYTSATSSAGQASLSLTF 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931595540 97 KFGTDMDRAADRMQQAVNRLGTQLPKDVRPT--VTAGSTEDFPAVVLAAGSTG--DQQKLADQLATSAVPELKKIAGVRD 172
Cdd:PRK09577 94 KQGVNADLAAVEVQNRLKTVEARLPEPVRRDgiQVEKAADNIQLIVSLTSDDGrlTGVELGEYASANVLQALRRVEGVGK 173
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931595540 173 VRVTGaAKETVTITVDYAKLAGAGVEPAALITALQSAGKPVPAGSLteGNRTL--------TVQVGGQLASVDALRDMYL 244
Cdd:PRK09577 174 VQFWG-AEYAMRIWPDPVKLAALGLTASDIASAVRAHNARVTIGDI--GRSAVpdsapiaaTVFADAPLKTPEDFGAIAL 250
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931595540 245 AGQRQ--PVRLADVASVEPRLAAATSLTRTNGKPSLGISIMMTSDGNAVDISEAVRGKLSGIGTTV--GAELTVIFDQGP 320
Cdd:PRK09577 251 RARADgsALYLRDVARIEFGGNDYNYPSYVNGKTATGMGIKLAPGSNAVATEKRVRATMDELSRYFppGVKYQIPYETSS 330
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931595540 321 YIQEAVKGLTTEGLLGLVFAVVVILLFLLSVRSTLVTAVSIPLSVMVALLALWTGDLSLNLLTLGALTIAVGRVVDDSIV 400
Cdd:PRK09577 331 FVRVSMNKVVTTLIEAGVLVFLVMFLFMQNFRATLIPTLVVPVALLGTFGVMLAAGFSINVLTMFGMVLAIGILVDDAIV 410
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931595540 401 VLENIKRHLAY-GEGKQRAVLDGVREVAGAVTASTLTTVAVFLPIAFVSGITGQLFSPFAVTVTVALLASLIVSLTIVPV 479
Cdd:PRK09577 411 VVENVERLMVEeGLSPYDATVKAMKQISGAIVGITVVLTSVFVPMAFFGGAVGNIYRQFALSLAVSIGFSAFLALSLTPA 490
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931595540 480 LAYWFLKPPKAGtdiaafreqaeAKERRGI---LQRAYVPVI-RFATR------RRLTTLLVALAILVGTFGLLSNLNTN 549
Cdd:PRK09577 491 LCATLLKPVDGD-----------HHEKRGFfgwFNRFVARSTqRYATRvgailkRPLRWLVVYGALTAAAALLFTRLPTA 559
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931595540 550 FLDDSGSTSMTVSQKLPPGSSIAARDDAARKVEGALAAEQGIeAYQVTIGsepGFG--GEVSSVNQFQVTL-----RKGT 622
Cdd:PRK09577 560 FLPDEDQGNFMVMVIRPQGTPLAETMQSVREVESYLRRHEPV-AYTFALG---GFNlyGEGPNGGMIFVTLkdwkeRKAA 635
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931595540 623 D--TKALQDRLVSRFKG--DTSAGEVKAGGDGGGFGSSDVSVVVKAPND---EALRAATDQVLAKVKGVQGLAEVTNDLA 695
Cdd:PRK09577 636 RdhVQAIVARINERFAGtpNTTVFAMNSPALPDLGSTSGFDFRLQDRGGlgyAAFVAAREQLLAEGAKDPALTDLMFAGT 715
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931595540 696 VSAPRVQIDVNERAAAAAGLSADTVGQLAGQAIAGFPVGEVSVAGK-RQQIVLRSGVAPKDVAAIRVMPLLTPTGP-VPL 773
Cdd:PRK09577 716 QDAPQLKLDIDRAKASALGVSMDEINTTLAVMFGSDYIGDFMHGSQvRRVIVQADGRHRLDPDDVKKLRVRNAQGEmVPL 795
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931595540 774 ERIAKVETVDGPVVVKRSESERSATV--TAKPvgkdlGTVNAELDTALKGL--KLGGGATYAIGGVSADQQEAfGDLGLA 849
Cdd:PRK09577 796 AAFATLHWTLGPPQLTRYNGYPSFTIngSAAP-----GHSSGEAMAAIERIaaTLPAGIGYAWSGQSFEERLS-GAQAPM 869
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931595540 850 LLA-AIVIVFAIMVATFRSFVQPLILLVSIPFAATGAFGLLLATGTPLGLPAMIGLLMLVGIVVTNAIVLIDLVNQYRRQ 928
Cdd:PRK09577 870 LFAlSVLVVFLALAALYESWSIPFAVMLVVPLGVIGAVLGVTLRGMPNDIYFKVGLIATIGLSAKNAILIVEVAKDLVAQ 949
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931595540 929 GMSIQDAVVEGGRRRLRPILMTASATIFALAPMAFGvTGEGAFIGKPLALVVIGGLVSSTLLTLVLVPTLYTMVERVKER 1008
Cdd:PRK09577 950 RMSLADAALEAARLRLRPIVMTSLAFGVGVLPLAFA-SGAASGAQIAIGTGVLGGVITATVLAVFLVPLFFVVVGRLFDV 1028
|
..
gi 931595540 1009 SR 1010
Cdd:PRK09577 1029 GP 1030
|
|
| PRK15127 |
PRK15127 |
multidrug efflux RND transporter permease subunit AcrB; |
17-1004 |
1.23e-64 |
|
multidrug efflux RND transporter permease subunit AcrB;
Pssm-ID: 185081 [Multi-domain] Cd Length: 1049 Bit Score: 237.49 E-value: 1.23e-64
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931595540 17 LITLAVIGFGAFAVPSLKQQLFPSIQPPTAMIVSPYPGAAPDVVSSQVTEPIEAGLQGTEGLEKLSSES-AEGISSIVAQ 95
Cdd:PRK15127 14 VIAIIIMLAGGLAILKLPVAQYPTIAPPAVTISASYPGADAKTVQDTVTQVIEQNMNGIDNLMYMSSNSdSTGTVQITLT 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931595540 96 FKFGTDMDRAADRMQQAVNRLGTQLPKDVRP--TVTAGSTEDFPAVV--LAAGSTGDQQKLADQLATSAVPELKKIAGVR 171
Cdd:PRK15127 94 FESGTDADIAQVQVQNKLQLAMPLLPQEVQQqgVSVEKSSSSFLMVVgvINTDGTMTQEDISDYVAANMKDPISRTSGVG 173
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931595540 172 DVRVTGAaKETVTITVDYAKLAGAGVEPAALITALQSAGKPVPAGSL--------TEGNRTLTVQVggQLASVDALRDMY 243
Cdd:PRK15127 174 DVQLFGS-QYAMRIWMNPNELNKFQLTPVDVINAIKAQNAQVAAGQLggtppvkgQQLNASIIAQT--RLTSTEEFGKIL 250
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931595540 244 LA----GQRqpVRLADVASVEPRLAAATSLTRTNGKPSLGISIMMTSDGNAVDISEAVRGKLSGIGTTVGAELTVIF--D 317
Cdd:PRK15127 251 LKvnqdGSR--VRLRDVAKIELGGENYDIIAEFNGQPASGLGIKLATGANALDTAAAIRAELAKMEPFFPSGLKIVYpyD 328
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931595540 318 QGPY----IQEAVKGLTtEGLLgLVFavVVILLFLLSVRSTLVTAVSIPLSVMVALLALWTGDLSLNLLTLGALTIAVGR 393
Cdd:PRK15127 329 TTPFvkisIHEVVKTLV-EAII-LVF--LVMYLFLQNFRATLIPTIAVPVVLLGTFAVLAAFGFSINTLTMFGMVLAIGL 404
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931595540 394 VVDDSIVVLENIKRHLA-YGEGKQRAVLDGVREVAGAVTASTLTTVAVFLPIAFVSGITGQLFSPFAVTVTVALLASLIV 472
Cdd:PRK15127 405 LVDDAIVVVENVERVMAeEGLPPKEATRKSMGQIQGALVGIAMVLSAVFVPMAFFGGSTGAIYRQFSITIVSAMALSVLV 484
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931595540 473 SLTIVPVLAYWFLKPPKAGTdiaafreqaEAKERRGIL----------QRAYVPVIRFATRRRLTTLLVALAILVGTFGL 542
Cdd:PRK15127 485 ALILTPALCATMLKPIAKGD---------HGEGKKGFFgwfnrmfeksTHHYTDSVGNILRSTGRYLVLYLIIVVGMAYL 555
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931595540 543 LSNLNTNFLDDSGSTSMTVSQKLPPGSSIAARDDAARKVEGALAAEQGIEAYQVTIGSEPGFGGEVSSVNQFQVTL---- 618
Cdd:PRK15127 556 FVRLPSSFLPDEDQGVFLTMVQLPAGATQERTQKVLNEVTDYYLTKEKNNVESVFAVNGFGFAGRGQNTGIAFVSLkdwa 635
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931595540 619 -RKGTDTK--ALQDRLVSRFkgdtsaGEVKAGGDGGGFGSSDVSVVVKAPND-----------EALRAATDQVLAKV-KG 683
Cdd:PRK15127 636 dRPGEENKveAITMRATRAF------SQIKDAMVFAFNLPAIVELGTATGFDfelidqaglghEKLTQARNQLLGEAaKH 709
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931595540 684 VQGLAEVTNDLAVSAPRVQIDVNERAAAAAGLSADTVGQLAGQAIAGFPVGEVSVAGKRQQIVLRSG----VAPKDVAAI 759
Cdd:PRK15127 710 PDMLVGVRPNGLEDTPQFKIDIDQEKAQALGVSISDINTTLGAAWGGSYVNDFIDRGRVKKVYVMSEakyrMLPDDIGDW 789
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931595540 760 RVMPllTPTGPVPLERIAKVETVDGPVVVKRSESERSATVTAKPV-GKDLGTVnAELDTALKGlKLGGGATYAIGGVSAd 838
Cdd:PRK15127 790 YVRA--ADGQMVPFSAFSSSRWEYGSPRLERYNGLPSMEILGQAApGKSTGEA-MELMEELAS-KLPTGVGYDWTGMSY- 864
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931595540 839 QQEAFGDLGLALLA-AIVIVFAIMVATFRSFVQPLILLVSIPFAATGAfgLLLAT--GTPLGLPAMIGLLMLVGIVVTNA 915
Cdd:PRK15127 865 QERLSGNQAPALYAiSLIVVFLCLAALYESWSIPFSVMLVVPLGVIGA--LLAATfrGLTNDVYFQVGLLTTIGLSAKNA 942
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931595540 916 IVLIDLVNQ-YRRQGMSIQDAVVEGGRRRLRPILMTASATIFALAPMAFGvTGEGAFIGKPLALVVIGGLVSSTLLTLVL 994
Cdd:PRK15127 943 ILIVEFAKDlMDKEGKGLIEATLEAVRMRLRPILMTSLAFILGVMPLVIS-SGAGSGAQNAVGTGVMGGMVTATVLAIFF 1021
|
1050
....*....|
gi 931595540 995 VPTLYTMVER 1004
Cdd:PRK15127 1022 VPVFFVVVRR 1031
|
|
| MMPL |
COG1033 |
Predicted exporter protein, RND superfamily [General function prediction only]; |
333-963 |
8.75e-27 |
|
Predicted exporter protein, RND superfamily [General function prediction only];
Pssm-ID: 440656 [Multi-domain] Cd Length: 767 Bit Score: 117.65 E-value: 8.75e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931595540 333 GLLGLVFAVVVILLFLLSVRSTLVTAVSIPLSVMVAL-LALWTGdLSLNLLT--LGALTIAVGrvVDDSIVVLENIKRHL 409
Cdd:COG1033 224 FPLALLLILLLLFLFFRSLRGVLLPLLVVLLAVIWTLgLMGLLG-IPLSPLTilVPPLLLAIG--IDYGIHLLNRYREER 300
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931595540 410 AYGEGKQRAVLDGVREVAGAVTASTLTTVAVFLPIAFvSGItgQLFSPFAVTVTVALLASLIVSLTIVPVLAYWFLKPpk 489
Cdd:COG1033 301 RKGLDKREALREALRKLGPPVLLTSLTTAIGFLSLLF-SDI--PPIRDFGIVAAIGVLLAFLTSLTLLPALLSLLPRP-- 375
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931595540 490 agtdiaafREQAEAKERRGILQRAYVPVIRFATRRRLTTLLVALAILVGTFGLLSNLNTNFLDDSgstsmtvsqklppgs 569
Cdd:COG1033 376 --------KPKTRRLKKPPELGRLLAKLARFVLRRPKVILVVALVLAVVSLYGISRLKVEYDFED--------------- 432
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931595540 570 siaarddaarkvegalaaeqgieayqvtigsepgfggevssvnqfqvTLRKGTDTKALQDRLVSRFKGDTSagevkaggd 649
Cdd:COG1033 433 -----------------------------------------------YLPEDSPIRQDLDFIEENFGGSDP--------- 456
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931595540 650 gggfgssdVSVVVKAPNDEALRaaTDQVLAKVKGVQglAEVTNDLAVSAPrvqidvneraaaaagLSADTVGQLAGQAIA 729
Cdd:COG1033 457 --------LEVVVDTGEPDGLK--DPEVLKEIDRLQ--DYLESLPEVGKV---------------LSLADLVKELNQALN 509
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931595540 730 GFPVGEVSVAGKRQQIVlrsgvapkdvaaiRVMPLLTPTGPVPLERIakvetvdgpvvvkRSESERSATVTAKPvgKDLG 809
Cdd:COG1033 510 EGDPKYYALPESRELLA-------------QLLLLLSSPPGDDLSRF-------------VDEDYSAARVTVRL--KDLD 561
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931595540 810 T-----VNAELDTALKGLKLGGGATYAIGG---VSADQQEA-FGDLGLALLAAIVIVFAIMVATFRSFVQPLILLVSIPF 880
Cdd:COG1033 562 SeeikaLVEEVRAFLAENFPPDGVEVTLTGsavLFAAINESvIESQIRSLLLALLLIFLLLLLAFRSLRLGLISLIPNLL 641
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931595540 881 AATGAFGLLLATGTPLGLPAMIGLLMLVGIVVTNAIVLIDLVNQYRRQGMSIQDAVVEGGRRRLRPILMTASATIFALAP 960
Cdd:COG1033 642 PILLTFGLMGLLGIPLNIATAVVASIALGIGVDYTIHFLSRYREERRKGGDLEEAIRRALRTTGKAILFTSLTLAAGFGV 721
|
...
gi 931595540 961 MAF 963
Cdd:COG1033 722 LLF 724
|
|
| MMPL |
COG1033 |
Predicted exporter protein, RND superfamily [General function prediction only]; |
335-484 |
1.47e-16 |
|
Predicted exporter protein, RND superfamily [General function prediction only];
Pssm-ID: 440656 [Multi-domain] Cd Length: 767 Bit Score: 84.91 E-value: 1.47e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931595540 335 LGLVFAVVVILLFLL--SVRSTLVTAVSIPLSVMVALLALWTGDLSLNLLTLGALTIAVGRVVDDSIVVLENIKRHLAYG 412
Cdd:COG1033 611 LLLALLLIFLLLLLAfrSLRLGLISLIPNLLPILLTFGLMGLLGIPLNIATAVVASIALGIGVDYTIHFLSRYREERRKG 690
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 931595540 413 EGKQRAVLDGVREVAGAVTASTLTTVAVFLPIAFvSGITGQlfSPFAVTVTVALLASLIVSLTIVPVLAYWF 484
Cdd:COG1033 691 GDLEEAIRRALRTTGKAILFTSLTLAAGFGVLLF-SSFPPL--ADFGLLLALGLLVALLAALLLLPALLLLL 759
|
|
| 2A0601 |
TIGR00914 |
heavy metal efflux pump, CzcA family; This model represents a family of H+/heavy metal cation ... |
147-500 |
5.81e-14 |
|
heavy metal efflux pump, CzcA family; This model represents a family of H+/heavy metal cation antiporters. This family is one of several subfamilies within the scope of pfam00873. [Cellular processes, Detoxification, Transport and binding proteins, Cations and iron carrying compounds]
Pssm-ID: 129992 [Multi-domain] Cd Length: 1051 Bit Score: 76.72 E-value: 5.81e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931595540 147 GDQQKLADQLATSAVPELKKIAGVRDVRV---TGAakETVTITVDYAKLAGAGVEPAALITALQSAGKPVPAGSLTEGNR 223
Cdd:TIGR00914 690 GDDLDDLDATAEKISAVLKGVPGAADVKVeqtTGL--PYLTVEIDREKAARYGLTVGDVQDTVATAVGGRMSGETFEGDR 767
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931595540 224 TLTVQV---GGQLASVDALRDMYL------AGQRQPVRLADVASVEpRLAAATSLTRTNGKPSLGISIMMTSD--GNAV- 291
Cdd:TIGR00914 768 RFDIVIrlpESLRESPQALRQLPIplplseDARKQFIPLSDVADLR-VSPGPNQISRENGKRRVVVSANVRGRdlGSFVd 846
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931595540 292 DISEAVRGKL---SGIGTTVGAEltviFDQgpyIQEAVKGLTTegLLGLVFAVVVILLFLL--SVRSTLVTAVSIPLSVM 366
Cdd:TIGR00914 847 DAKKAIAEQVklpPGYWITWGGQ----FEQ---LQSATKRLQI--VVPVTLLLIFVLLYAAfgNVKDALLVFTGIPFALT 917
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931595540 367 VALLALWTGDLSLNLLTLGALTIAVGRVVDDSIVVLENIKRHLAYGEGKQRAVLDGVREVAGAVTASTLTTVAVFLPIAF 446
Cdd:TIGR00914 918 GGVFALWLRGIPLSISAAVGFIALSGVAVLNGLVMISFIRKLLEEGPSLDEAVYEGALTRVRPVLMTALVASLGFVPMAI 997
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....
gi 931595540 447 VSGITGQLFSPFAVTVTVALLASLIVSLTIVPVLAYWFLKPPKAGTDIAAFREQ 500
Cdd:TIGR00914 998 ATGTGAEVQRPLATVVIGGIITATLLTLFVLPALYRLVHRRRHKGRKEHEPLEG 1051
|
|
| MMPL |
COG1033 |
Predicted exporter protein, RND superfamily [General function prediction only]; |
759-963 |
2.12e-13 |
|
Predicted exporter protein, RND superfamily [General function prediction only];
Pssm-ID: 440656 [Multi-domain] Cd Length: 767 Bit Score: 74.51 E-value: 2.12e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931595540 759 IRVMPLLTPTGPVPLERIAKV--ETVDGPVVVKR--SESERSATVTAKPVG------KDLGTVNAELDTALKGLKLGGGA 828
Cdd:COG1033 120 LTVEPLIPDELPASPEELAELreKVLSSPLYVGRlvSPDGKATLIVVTLDPdplssdLDRKEVVAEIRAIIAKYEDPGVE 199
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931595540 829 TYAIGGV---SADQQEAFGDLGLALLAAIVIVFAIMVATFRSFVQPLILLVSIPFAATGAFGLLLATGTPLGLPAMIGLL 905
Cdd:COG1033 200 VYLTGFPvlrGDIAEAIQSDLAIFFPLALLLILLLLFLFFRSLRGVLLPLLVVLLAVIWTLGLMGLLGIPLSPLTILVPP 279
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 931595540 906 MLVGIVVTNAIVLIDLVNQYRRQGMSIQDAVVEGGRRRLRPILMTASATIFALAPMAF 963
Cdd:COG1033 280 LLLAIGIDYGIHLLNRYREERRKGLDKREALREALRKLGPPVLLTSLTTAIGFLSLLF 337
|
|
| YdfJ |
COG2409 |
Predicted lipid transporter YdfJ, MMPL/SSD domain, RND superfamily [General function ... |
773-963 |
1.26e-09 |
|
Predicted lipid transporter YdfJ, MMPL/SSD domain, RND superfamily [General function prediction only];
Pssm-ID: 441964 [Multi-domain] Cd Length: 697 Bit Score: 62.09 E-value: 1.26e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931595540 773 LERIAKVETVDGPVVVK----RSESERSATVTAKPVGKDLGTVNAELDTALKGLK--LGGGATYAIGG---VSADQQEAF 843
Cdd:COG2409 88 LRADPGVAGVQDPWDDPaaglVSEDGKAALVTVTLDGDAGDEAAEAVDALRDAVAaaPAPGLTVYVTGpaaLAADLNEAF 167
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931595540 844 -GDLGLALLAAIVIVFAIMVATFRSFVQPLILLVSIPFAATGAFGLLLATGTPLGLPAM-IGLLMLVGIVVTnaivlID- 920
Cdd:COG2409 168 eEDLGRAELITLPVALVVLLLVFRSLVAALLPLLTAGLAVGVALGLLALLAAFTDVSSFaPNLLTMLGLGVG-----IDy 242
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 931595540 921 ---LVNQYR---RQGMSIQDAVVEGGRRRLRPILMTASATIFALAPMAF 963
Cdd:COG2409 243 alfLVSRYReelRAGEDREEAVARAVATAGRAVLFSGLTVAIALLGLLL 291
|
|
| actII |
TIGR00833 |
Transport protein; The Resistance-Nodulation-Cell Division (RND) Superfamily- MmpL sub family ... |
303-888 |
1.09e-08 |
|
Transport protein; The Resistance-Nodulation-Cell Division (RND) Superfamily- MmpL sub family (TC 2.A.6.5)Characterized members of the RND superfamily all probably catalyze substrate efflux via an H+ antiport mechanism. These proteins are found ubiquitously in bacteria, archaea and eukaryotes. This sub-family includes the S. coelicolor ActII3 protein, which may play a role in drug resistance, and the M. tuberculosis MmpL7 protein, which catalyzes export of an outer membrane lipid, phthiocerol dimycocerosate. [Transport and binding proteins, Unknown substrate]
Pssm-ID: 129913 [Multi-domain] Cd Length: 910 Bit Score: 59.21 E-value: 1.09e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931595540 303 GIGTTVGAELTVIFDQGPYIQEAVKGLTtegllgLVFAVVVILLFLLSVRS---TLVTAVSIPLSVMVAL----LALWTG 375
Cdd:TIGR00833 152 GLTVHVTGPLATIADILESGDKDMNRIT------ATTGIIVLIILLLVYRSpitMLVPLVSVGFSVVVAQgivsLLGIPG 225
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931595540 376 DLSLNLLTLGALT-IAVGRVVDDSIVVLENIKRHLAYGEGKQRAVLDGVREVAGAVTASTLTTVAVFLPIAFVS-GITGQ 453
Cdd:TIGR00833 226 LIGVNAQTTVLLTaLVIGAGTDYAVFLTGRYHEERRKGESLEEAAAEALRGTGKAILGSALTVAVAFLALSLARlPSFKT 305
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931595540 454 LFSPFAVTVTVALLASLIVSLTIVPVLAYWFLKPPKagtdiaafreqaEAKERRGILQRAYVPVIRFATRRRLTTLLVAL 533
Cdd:TIGR00833 306 LGVSCAVGVLVALLNAVTLTPALLTLEGREGLMKPG------------RKSKIRFIWRRLGTAVVRRPWPILVTTLIISG 373
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931595540 534 AILVGTFGL-------------------LSNLNTNFLDDSGsTSMTVSQKLPPGSSIAARDDAARKVEGALAAEQGIEAY 594
Cdd:TIGR00833 374 VSLLALPLIrtgyddekmiptdlesvqgYEAADRHFPGNSM-DPMVVMIKSDHDVRNPALLADIDRFEREIKAVPGINMV 452
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931595540 595 QVTIGSEPGFGGEVSSVNQFQVTLRKGTDTKALQDRLVSRFKGDTSA--------GEVKAGGDGGGFGSSDVSVVVKAPN 666
Cdd:TIGR00833 453 QETQRPDGVVIKKTYLTFQAGNLGDQLDEFSDQLTSRQAYLLQDAEKiaeaiaglRLVQAGMRLDGENLGQVSLAVRLMQ 532
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931595540 667 DEALRAAT------DQVLAKVKGVQGLAEVTNDLAVSAPRVQIDVNERAAAAAGLSADTVGQLA------GQAIAGFPVG 734
Cdd:TIGR00833 533 QAISKLQGsagdvfDIFDPLRRFVAAIPECRANPVCSVAREIVQAADTVVSSAAKLADAAGQLArgiadvASALSQVSGL 612
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931595540 735 EVSVAGKRQQIVLRSGVAPKDVAAIRVMPLLTPTGPVPLERIAKVETVDGPVVVKRSESERSATVTAKPVG--------- 805
Cdd:TIGR00833 613 PNALDGIGTQLAQMRESAAGVQDLLNELSDYSMTMGKLKGNAMGVDFYAPPRIFTDPNFKAVLDYFLSPDGhaarllvyg 692
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931595540 806 -------KDLGTVNAELDTALKGLKLGG--GATYAIGGVSA---DQQEAFG-DLGLALLAAIVIVFAIMVATFRSFVQPL 872
Cdd:TIGR00833 693 dgspagdQGAQEFNAIRTVAEEAIQRADlePAKVELAGVSAvnrDLRDLVNsDLGLISIITLAIVFMILALLLRAPVAPI 772
|
650
....*....|....*.
gi 931595540 873 ILLVSIPFAATGAFGL 888
Cdd:TIGR00833 773 VLIGSVALSYLWALGL 788
|
|
| MMPL |
pfam03176 |
MMPL family; Members of this family are putative integral membrane proteins from bacteria. ... |
327-507 |
1.31e-08 |
|
MMPL family; Members of this family are putative integral membrane proteins from bacteria. Several of the members are mycobacterial proteins. Many of the proteins contain two copies of this aligned region. The function of these proteins is not known, although it has been suggested that they may be involved in lipid transport.
Pssm-ID: 308676 [Multi-domain] Cd Length: 332 Bit Score: 57.69 E-value: 1.31e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931595540 327 KGLTTEGLLGLVFAVVVILLFLLSVRSTLVTAVSIPLSVMVA--LLALW--TGDLSLNLLTLG---ALTIAVGrvVDDSI 399
Cdd:pfam03176 142 RDLGLIEAVTLVVIFIILLIVYRSVVAALLPLLTVGLSLGAAqgLVAILahILGIGLSTFALNllvVLLIAVG--TDYAL 219
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931595540 400 VVLENIKRHLAYGEGKQRAVLDGVREVAGAVTASTLTTVAVFLPIAFVS-GITGQLFSPFAVTVTVALLASLIVSLTIVP 478
Cdd:pfam03176 220 FLVSRYREELRAGEDREEAVIRAVRGTGKVVTAAGLTVAIAMLALSFARlPVFAQVGPTIAIGVLVDVLAALTLLPALLA 299
|
170 180
....*....|....*....|....*....
gi 931595540 479 VLAYWFLKPPKAGTDIAAFREQAEAKERR 507
Cdd:pfam03176 300 LLGRWGLWPPKRDRTARWWRRIGRLVVRR 328
|
|
| 2A067 |
TIGR00921 |
The (Largely Archaeal Putative) Hydrophobe/Amphiphile Efflux-3 (HAE3) Family; Characterized ... |
834-981 |
2.37e-08 |
|
The (Largely Archaeal Putative) Hydrophobe/Amphiphile Efflux-3 (HAE3) Family; Characterized members of the RND superfamily all probably catalyze substrate efflux via an H+ antiport mechanism. These proteins are found ubiquitously in bacteria, archaea and eukaryotes. They fall into seven phylogenetic families, this family (2.A.6.7) consists of uncharacterised putative transporters, largely in the Archaea. [Transport and binding proteins, Unknown substrate]
Pssm-ID: 273340 [Multi-domain] Cd Length: 719 Bit Score: 58.31 E-value: 2.37e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931595540 834 GVSADQQEAFG-DLGLALLAAIVIVFAIMVATFRSFVQPLILLVSIPFAATGAFGLLLATGTPLGLPAMIGLLMLVGIVV 912
Cdd:TIGR00921 182 AINYDIEREFGkDMGTTMAISGILVVLVLLLDFKRWWRPLLPLVIILFGVAWVLGIMGWLGIPLYATTLLAVPMLIGVGI 261
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 931595540 913 TNAIVLIDLVNQYRRQGMSIQDAVVEGGRRRLRPILMTASATIFALAPMAFGVTGEGAFIGKPLALVVI 981
Cdd:TIGR00921 262 DYGIQTLNRYEEERDIGRAKGEAIVTAVRRTGRAVLIALLTTSAGFAALALSEFPMVSEFGLGLVAGLI 330
|
|
| MMPL |
pfam03176 |
MMPL family; Members of this family are putative integral membrane proteins from bacteria. ... |
817-986 |
2.70e-08 |
|
MMPL family; Members of this family are putative integral membrane proteins from bacteria. Several of the members are mycobacterial proteins. Many of the proteins contain two copies of this aligned region. The function of these proteins is not known, although it has been suggested that they may be involved in lipid transport.
Pssm-ID: 308676 [Multi-domain] Cd Length: 332 Bit Score: 56.92 E-value: 2.70e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931595540 817 TALKGLKLGGGATYAIGGVSA---DQQEAF-GDLGLALLAAIVIVFAIMVATFRSFVQPLILLVSIPFAATGAFGLLLAT 892
Cdd:pfam03176 111 DAVEQAPPPEGLKAYLTGPAAtvaDLRDAGdRDLGLIEAVTLVVIFIILLIVYRSVVAALLPLLTVGLSLGAAQGLVAIL 190
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931595540 893 GTPLGLP-----AMIGLLMLVGIVVTNAIVLIDLVNQYRRQGMSIQDAVVEGGRRRLRPIlmTASATIFALAPMAFGVTG 967
Cdd:pfam03176 191 AHILGIGlstfaLNLLVVLLIAVGTDYALFLVSRYREELRAGEDREEAVIRAVRGTGKVV--TAAGLTVAIAMLALSFAR 268
|
170 180
....*....|....*....|..
gi 931595540 968 EGAF--IGKPLAL-VVIGGLVS 986
Cdd:pfam03176 269 LPVFaqVGPTIAIgVLVDVLAA 290
|
|
| PRK09579 |
PRK09579 |
multidrug efflux RND transporter permease subunit; |
835-987 |
7.69e-08 |
|
multidrug efflux RND transporter permease subunit;
Pssm-ID: 169983 [Multi-domain] Cd Length: 1017 Bit Score: 56.77 E-value: 7.69e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931595540 835 VSADQQEAFGDLGLALLAAIVIVFaIMVATFRSFVQPLillVSIPFAATGAFGLLLATGTPLGLPAMIGLLMLVGIVVTN 914
Cdd:PRK09579 326 IQASIDEVVKTLGEAVLIVIVVVF-LFLGALRSVLIPV---VTIPLSMIGVLFFMQMMGYSINLLTLLAMVLAIGLVVDD 401
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 931595540 915 AIVLIDLVNQYRRQGMSIQDAVVEGGRRRLRPILMTASATIFALAPMAFgVTGEGAFIGKPLALVVIGGLVSS 987
Cdd:PRK09579 402 AIVVVENIHRHIEEGKSPFDAALEGAREIAMPVVSMTITLAAVYAPIGF-LTGLTGALFKEFALTLAGAVIIS 473
|
|
| PRK13024 |
PRK13024 |
bifunctional preprotein translocase subunit SecD/SecF; Reviewed |
306-562 |
9.12e-08 |
|
bifunctional preprotein translocase subunit SecD/SecF; Reviewed
Pssm-ID: 237276 [Multi-domain] Cd Length: 755 Bit Score: 56.39 E-value: 9.12e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931595540 306 TTVGAELTvifdqgpyiQEAVKGLTTEGLLGlvFAVVVILLFLLSVRSTLVTAVSIPLSVMVALLALwtgdLSLN-LLTL 384
Cdd:PRK13024 254 RSVGPTLG---------QDAIDAGIIAGIIG--FALIFLFMLVYYGLPGLIANIALLLYIFLTLGAL----SSLGaVLTL 318
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931595540 385 G---ALTIAVGRVVDDSIVVLENIKRHLAYGEGKQRAVLDGVREVAGAVTASTLTTV--AVFLPIaFVSG-ITGqlfspF 458
Cdd:PRK13024 319 PgiaGLVLGIGMAVDANVLIFERIKEELRKGKSLKKAFKKGFKNAFSTILDSNITTLiaAAILFF-FGTGpVKG-----F 392
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931595540 459 AVTVTVALLASLIVSLTIVPVLAYWFLKPPKAGTDIAAFREQAEAKERRGILQRayvPVIRFATRRRLTTLLVALAILVG 538
Cdd:PRK13024 393 ATTLIIGILASLFTAVFLTRLLLELLVKRGDKKPFLFGVKKKKIHNINEGVTIF---DRIDFVKKRKWFLIFSIVLVIAG 469
|
250 260
....*....|....*....|....*....
gi 931595540 539 -----TFGLlsNLNTNFlddSGSTSMTVS 562
Cdd:PRK13024 470 iiiffIFGL--NLGIDF---TGGTRYEIR 493
|
|
| 2A067 |
TIGR00921 |
The (Largely Archaeal Putative) Hydrophobe/Amphiphile Efflux-3 (HAE3) Family; Characterized ... |
334-541 |
5.06e-07 |
|
The (Largely Archaeal Putative) Hydrophobe/Amphiphile Efflux-3 (HAE3) Family; Characterized members of the RND superfamily all probably catalyze substrate efflux via an H+ antiport mechanism. These proteins are found ubiquitously in bacteria, archaea and eukaryotes. They fall into seven phylogenetic families, this family (2.A.6.7) consists of uncharacterised putative transporters, largely in the Archaea. [Transport and binding proteins, Unknown substrate]
Pssm-ID: 273340 [Multi-domain] Cd Length: 719 Bit Score: 53.69 E-value: 5.06e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931595540 334 LLGLVFAVVVILLFLL--SVRSTLVTAVSIPLSVMVALLALWTGDLSLNLLTLGALTIAVGRVVDDSIVVLENIKRHLAY 411
Cdd:TIGR00921 198 TMAISGILVVLVLLLDfkRWWRPLLPLVIILFGVAWVLGIMGWLGIPLYATTLLAVPMLIGVGIDYGIQTLNRYEEERDI 277
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931595540 412 GEGKQRAVLDGVREVAGAVTASTLTTVAVFLPIaFVSGItgQLFSPFAVTVTVALLASLIVSLTIVPVLAY---WFLKPP 488
Cdd:TIGR00921 278 GRAKGEAIVTAVRRTGRAVLIALLTTSAGFAAL-ALSEF--PMVSEFGLGLVAGLITAYLLTLLVLPALLQsidIGREKV 354
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 931595540 489 KagtdiaafREQAEAKERRGILQRAYVPVIRFATRRRLTTLLVALAI-LVGTFG 541
Cdd:TIGR00921 355 K--------KEIIAIGGKSSEIEEELSKVLSITVRHPVPALVAALIItGLGLYG 400
|
|
| YdfJ |
COG2409 |
Predicted lipid transporter YdfJ, MMPL/SSD domain, RND superfamily [General function ... |
323-631 |
4.33e-06 |
|
Predicted lipid transporter YdfJ, MMPL/SSD domain, RND superfamily [General function prediction only];
Pssm-ID: 441964 [Multi-domain] Cd Length: 697 Bit Score: 50.92 E-value: 4.33e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931595540 323 QEAVKGLTTEGLLGLVFAVVVILLFLLSVRSTLVTAVSIPLSVMVA--LLALWTGDLSLNLLTLGALT---IAVGrvVDD 397
Cdd:COG2409 165 EAFEEDLGRAELITLPVALVVLLLVFRSLVAALLPLLTAGLAVGVAlgLLALLAAFTDVSSFAPNLLTmlgLGVG--IDY 242
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931595540 398 SIVVlenIKRH---LAYGEGKQRAVLDGVREVAGAVTASTLTTVAVFLPIaFVSGITgqLFSPFAVTVTVALLASLIVSL 474
Cdd:COG2409 243 ALFL---VSRYreeLRAGEDREEAVARAVATAGRAVLFSGLTVAIALLGL-LLAGLP--FLRSMGPAAAIGVAVAVLAAL 316
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931595540 475 TIVP----VLAYWFLKPPKAgtdiaafREQAEAKERRGILQRayvpVIRFATRRRLTTLLVALAILVGTFGLLSNLNTNF 550
Cdd:COG2409 317 TLLPallaLLGRRVFWPRRP-------RRRRAAAPESGFWRR----LARAVVRRPVPVLVAAVAVLLALALPALGLRLGL 385
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931595540 551 LDDS----GSTSMTVSQKL----PPGS-------------SIAARDDAARKVEGALAAEQGIEAYQVtIGSEPGFGGEVS 609
Cdd:COG2409 386 PDADslpaDSPSRQGYDALaehfPPGSngpltvvvesdddLDPADLAALDALAAALAAVPGVASVQP-PTRPEGTDGDAA 464
|
330 340
....*....|....*....|..
gi 931595540 610 svnQFQVTLRKGTDTKALQDRL 631
Cdd:COG2409 465 ---RLQVVPDGDPDSPEAIDLV 483
|
|
| PRK08578 |
PRK08578 |
preprotein translocase subunit SecF; Reviewed |
785-986 |
1.98e-05 |
|
preprotein translocase subunit SecF; Reviewed
Pssm-ID: 236302 [Multi-domain] Cd Length: 292 Bit Score: 47.62 E-value: 1.98e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931595540 785 PVVVKRSESERSATVTAKPVGK-DLGTVNAELDTALKGLKLGG--------GATYAiggvSADQQEAFGDLGLALLAAIV 855
Cdd:PRK08578 74 PGVDVRKGSGNGYIITFGSGDDtDVDKLADAVKEFFNVDSISElnysekqiGPTFG----SQFQEQALKAVGFAFIGMAV 149
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931595540 856 IVFAImvatFRSFVQPLILLVS------IPFAATGAFGLLLATGTplglpaMIGLLMLVGIVVTNAIVLIDLVnqYRRQG 929
Cdd:PRK08578 150 VVFLI----FRTPVPSLAVILSafsdiiIALALMNLFGIELSLAT------VAALLMLIGYSVDSDILLTTRV--LKRRG 217
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 931595540 930 M---SIQDAVVEGgrrrlrpILMTaSATIFALAPMAFGVTGEGAFIGKPLALVVIGGLVS 986
Cdd:PRK08578 218 TfdeSIKRAMRTG-------ITMT-LTTIAAMAVLYIVSTIPQAEVLANIAAVLIFGLLA 269
|
|
| 2A0604s01 |
TIGR00916 |
protein-export membrane protein, SecD/SecF family; The SecA,SecB,SecD,SecE,SecF,SecG and SecY ... |
333-474 |
3.25e-05 |
|
protein-export membrane protein, SecD/SecF family; The SecA,SecB,SecD,SecE,SecF,SecG and SecY proteins form the protein translocation appartus in prokaryotes. This family is specific for the SecD and SecF proteins. [Protein fate, Protein and peptide secretion and trafficking]
Pssm-ID: 273336 [Multi-domain] Cd Length: 192 Bit Score: 45.71 E-value: 3.25e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931595540 333 GLLGLVFAVVVILLFLL---SVRSTL--VTAVSIPLSVMVALLALWtgDLSLNLLTLGALTIAVGRVVDDSIVVLENIKR 407
Cdd:TIGR00916 49 GIIALLIGLVLVLLYMLlryEWRGAIaaIAALVHDVILILGVLSLF--GATLTLPGIAGLLTIIGYSVDDTVVIFDRIRE 126
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 931595540 408 HLAYGEGK--QRAVLDGVREvagAVTASTLTTVAVFLPIAFVSGITGQLFSPFAVTVTVALLASLIVSL 474
Cdd:TIGR00916 127 ELRKYKGRtfREAINLGINQ---TLSRIIDTNVTTLLAVLALYVFGGGAIKGFALTLGIGVIAGTYSSI 192
|
|
| PRK12911 |
PRK12911 |
bifunctional preprotein translocase subunit SecD/SecF; Reviewed |
331-474 |
8.22e-05 |
|
bifunctional preprotein translocase subunit SecD/SecF; Reviewed
Pssm-ID: 171815 [Multi-domain] Cd Length: 1403 Bit Score: 46.78 E-value: 8.22e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931595540 331 TEGLLGLVFAVVViLLFLLSVRSTLvTAVSIPLSVMVALLALWTG----DLSLNLLTLGALTIAVGRVVDDSIVVLENIK 406
Cdd:PRK12911 909 TQGIISVCLGLAV-LIVLMSVYYRF-GGVIASGAVLLNLLLIWAAlqylDAPLTLSGLAGIVLAMGMAVDANVLVFERIR 986
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 931595540 407 RHLAYGEGKQRAVLDGVREVAGAVTASTLTTVAVFLPIAFVSgiTGQLfSPFAVTVTVALLASLIVSL 474
Cdd:PRK12911 987 EEYLLSRSLSESVEAGYKKAFSAIFDSNLTTILASALLLMLD--TGPI-KGFALTLIIGIFSSMFTAL 1051
|
|
| COG4258 |
COG4258 |
Predicted exporter [General function prediction only]; |
334-478 |
1.25e-04 |
|
Predicted exporter [General function prediction only];
Pssm-ID: 443400 [Multi-domain] Cd Length: 783 Bit Score: 46.00 E-value: 1.25e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931595540 334 LLGLVFAVVVILLFLLSVRSTLVTAVSIPLSVMVALLALWTGDLSLNLLTLGALTIAVGRVVDDSIVVLEnikrHLAYGE 413
Cdd:COG4258 646 LLALLLILLLLLLRLRSLRRALRVLLPPLLAVLLTLAILGLLGIPLNLFHLIALLLVLGIGIDYALFFTE----GLLDKG 721
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 931595540 414 GKQRAVLdgvrevagAVTASTLTTVAVFLPIAFvSGItgQLFSPFAVTVTVALLASLIVSLTIVP 478
Cdd:COG4258 722 ELARTLL--------SILLAALTTLLGFGLLAF-SST--PALRSFGLTVLLGILLALLLAPLLAP 775
|
|
| COG4258 |
COG4258 |
Predicted exporter [General function prediction only]; |
333-481 |
3.91e-04 |
|
Predicted exporter [General function prediction only];
Pssm-ID: 443400 [Multi-domain] Cd Length: 783 Bit Score: 44.46 E-value: 3.91e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931595540 333 GLLGLVFAVVVILLFLLSVRSTLVTAVSIPLSVMVALLALWTGDLSLNLLTLGALTIAVGRVVDDSIVVLenikrhLAYG 412
Cdd:COG4258 255 GLISLLGILLLLLLVFRSLRPLLLGLLPVAVGALAGLAAVSLVFGSVHGITLGFGSSLIGVAVDYSLHYL------THRR 328
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 931595540 413 EGKQRAVLDGVREVAGAVTASTLTTVAVFLpiafvsgitGQLFSPF------AVTVTVALLASLIVSLTIVPVLA 481
Cdd:COG4258 329 AAGEWDPRAALRRIWPTLLLGLLTTVLGYL---------ALLFSPFpglrqlGVFAAAGLLAAALTTLLWLPLLL 394
|
|
| secD |
TIGR01129 |
protein-export membrane protein SecD; Members of this family are highly variable in length ... |
849-987 |
4.91e-04 |
|
protein-export membrane protein SecD; Members of this family are highly variable in length immediately after the well-conserved motif LGLGLXGG at the amino-terminal end of this model. Archaeal homologs are not included in the seed and score between the trusted and noise cutoffs. SecD from Mycobacterium tuberculosis has a long Pro-rich insert. [Protein fate, Protein and peptide secretion and trafficking]
Pssm-ID: 273456 [Multi-domain] Cd Length: 397 Bit Score: 43.82 E-value: 4.91e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931595540 849 ALLAAIVIVFAIMVATFRSF--VQPLILLVSIpFAATGAFGLLLATgtpLGLPAMIGLLMLVGIVVTNAIVLIDLVNQYR 926
Cdd:TIGR01129 253 AGLIGLVLVLVFMILYYRLFglIAAIALVINI-VLILAILSAFGAT---LTLPGIAGLILTIGMAVDANVLIYERIKEEL 328
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 931595540 927 RQGMSIQDAVVEGGRRRLRPIlMTASATIFaLAPMAFGVTGEGAFIGkpLALVVIGGLVSS 987
Cdd:TIGR01129 329 RLGKSVRQAIEAGFERAFSTI-FDANITTL-IAALILYVFGTGPVKG--FAVTLAIGIIAS 385
|
|
| PRK12911 |
PRK12911 |
bifunctional preprotein translocase subunit SecD/SecF; Reviewed |
262-480 |
7.80e-04 |
|
bifunctional preprotein translocase subunit SecD/SecF; Reviewed
Pssm-ID: 171815 [Multi-domain] Cd Length: 1403 Bit Score: 43.69 E-value: 7.80e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931595540 262 RLAAATSLTRTNGKPSLGISIMMTSDgNAVDISEAVRGKLSGIGTTVGAELTvifdqgpyiqeavKGLTTEGLLGLVFAV 341
Cdd:PRK12911 1179 RVEAIEGAGSEQSDHHLALVLGVLSD-TGSDTSSEVFDATQNFWFKVSGQLS-------------NKMRTQAVIALFGAL 1244
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931595540 342 VVILLFLlSVRSTLVTAVSIPLSVMVALLA---------LWTGDLSLNLLTLGALTIAVGRVVDDSIVVLENIKrhlayg 412
Cdd:PRK12911 1245 GIILLYV-SLRFEWRYAFSAICALIHDLLAtcavlvalhFFLQKIQIDLQAIGALMTVLGYSLNNTLIIFDRIR------ 1317
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 931595540 413 EGKQRAVL--------DGVREVAGAVTASTLTTVAVFLPIAFVSGitGQLFSpFAVTVTVALLASLIVSLTIVPVL 480
Cdd:PRK12911 1318 EDRQEKLFtpmpilinDALQKTLGRTVMTTATTLSVLLILLFVGG--GSIFN-FAFIMTIGILLGTLSSLYIAPPL 1390
|
|
| 2A067 |
TIGR00921 |
The (Largely Archaeal Putative) Hydrophobe/Amphiphile Efflux-3 (HAE3) Family; Characterized ... |
319-480 |
1.07e-03 |
|
The (Largely Archaeal Putative) Hydrophobe/Amphiphile Efflux-3 (HAE3) Family; Characterized members of the RND superfamily all probably catalyze substrate efflux via an H+ antiport mechanism. These proteins are found ubiquitously in bacteria, archaea and eukaryotes. They fall into seven phylogenetic families, this family (2.A.6.7) consists of uncharacterised putative transporters, largely in the Archaea. [Transport and binding proteins, Unknown substrate]
Pssm-ID: 273340 [Multi-domain] Cd Length: 719 Bit Score: 42.90 E-value: 1.07e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931595540 319 GPYIQ-EAVKGLTTEGLLGLVFAVVVILLFLLSVRSTLVTAVSiPLSVMVaLLALWTGDL--------SLNLLTLGALTI 389
Cdd:TIGR00921 554 LPVAFaEMHELVNEGMRRMTIAGAILVLMILLAVFRNPIKAVF-PLIAIG-SGILWAIGLmglrgipsFLAMATTISIIL 631
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931595540 390 AVGrvVDDSIVVLENIKRHLAyGEGKQRAVLDGVREVAGAVTASTLTTVAVFLpiAFVSGITGqLFSPFAVTVTVALLAS 469
Cdd:TIGR00921 632 GLG--MDYSIHLAERYFEERK-EHGPKEAITHTMERTGPGILFSGLTTAGGFL--SLLLSHFP-IMRNFGLVQGIGVLSS 705
|
170
....*....|.
gi 931595540 470 LIVSLTIVPVL 480
Cdd:TIGR00921 706 LTAALVVFPAL 716
|
|
| actII |
TIGR00833 |
Transport protein; The Resistance-Nodulation-Cell Division (RND) Superfamily- MmpL sub family ... |
833-986 |
2.41e-03 |
|
Transport protein; The Resistance-Nodulation-Cell Division (RND) Superfamily- MmpL sub family (TC 2.A.6.5)Characterized members of the RND superfamily all probably catalyze substrate efflux via an H+ antiport mechanism. These proteins are found ubiquitously in bacteria, archaea and eukaryotes. This sub-family includes the S. coelicolor ActII3 protein, which may play a role in drug resistance, and the M. tuberculosis MmpL7 protein, which catalyzes export of an outer membrane lipid, phthiocerol dimycocerosate. [Transport and binding proteins, Unknown substrate]
Pssm-ID: 129913 [Multi-domain] Cd Length: 910 Bit Score: 41.88 E-value: 2.41e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931595540 833 GGVSADQQEAF-GDLGLALLAAIVIVFAIMVATFRSFVQPLILLVSIPFAATGAFGLLLATGTPLGLP-----AMIGLLM 906
Cdd:TIGR00833 161 LATIADILESGdKDMNRITATTGIIVLIILLLVYRSPITMLVPLVSVGFSVVVAQGIVSLLGIPGLIGvnaqtTVLLTAL 240
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931595540 907 LVGIVVTNAIVLIDLVNQYRRQGMSIQDAVVEGGRRRLRPILMTASATIFALAPMAFGVTGEGAFIGKPLALVVIGGLVS 986
Cdd:TIGR00833 241 VIGAGTDYAVFLTGRYHEERRKGESLEEAAAEALRGTGKAILGSALTVAVAFLALSLARLPSFKTLGVSCAVGVLVALLN 320
|
|
| COG4258 |
COG4258 |
Predicted exporter [General function prediction only]; |
844-910 |
2.65e-03 |
|
Predicted exporter [General function prediction only];
Pssm-ID: 443400 [Multi-domain] Cd Length: 783 Bit Score: 41.76 E-value: 2.65e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 931595540 844 GDLGLALLAAIVIVFAIMVATFRSFVQPLILLVSIPFAATGAFGLLLATGTPLGLPAMIGLLMLVGI 910
Cdd:COG4258 639 NDALWLLLLALLLILLLLLLRLRSLRRALRVLLPPLLAVLLTLAILGLLGIPLNLFHLIALLLVLGI 705
|
|
| HpnN |
TIGR03480 |
hopanoid biosynthesis associated RND transporter like protein HpnN; The genomes containing ... |
336-565 |
4.37e-03 |
|
hopanoid biosynthesis associated RND transporter like protein HpnN; The genomes containing members of this family share the machinery for the biosynthesis of hopanoid lipids. Furthermore, the genes of this family are usually located proximal to other components of this biological process. The proteins appear to be related to the RND family of export proteins, particularly the hydrophobe/amphiphile efflux-3 (HAE3) family represented by TIGR00921.
Pssm-ID: 274598 [Multi-domain] Cd Length: 862 Bit Score: 41.14 E-value: 4.37e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931595540 336 GLVFAVVVILLFLLSVRS------TLVTAVsIPLSVMVALLALWTGdlSLNLLTLGALTIAVGRVVDDSIVVLENIKRHL 409
Cdd:TIGR03480 275 GLLSFVLVLVLLWLALRSprlvfaVLVTLI-VGLILTAAFATLAVG--HLNLISVAFAVLFIGLGVDFAIQFSLRYREER 351
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931595540 410 AYGEGKQRAVLDGVREVAGAVTASTLTTVA---VFLPIAFvSGItgqlfSPFAVTVTVALLASLIVSLTIVPVLaywflk 486
Cdd:TIGR03480 352 FRGGNHREALSVAARRMGAALLLAALATAAgffAFLPTDY-KGV-----SELGIIAGTGMFIALFVTLTVLPAL------ 419
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931595540 487 ppkagtdIAAFREQAEAKERRGILQRayvPVIRFATRRRLTTLLVALAILVGTFGLLSNLNTNF----LDDSGSTSMTVS 562
Cdd:TIGR03480 420 -------LRLLRPPRRRKPPGYATLA---PLDAFLRRHRRPVLGVTLILGIAALALLPQLRFDFnplnLQDPKTESVRTF 489
|
...
gi 931595540 563 QKL 565
Cdd:TIGR03480 490 LEL 492
|
|
| HpnN |
TIGR03480 |
hopanoid biosynthesis associated RND transporter like protein HpnN; The genomes containing ... |
333-481 |
4.67e-03 |
|
hopanoid biosynthesis associated RND transporter like protein HpnN; The genomes containing members of this family share the machinery for the biosynthesis of hopanoid lipids. Furthermore, the genes of this family are usually located proximal to other components of this biological process. The proteins appear to be related to the RND family of export proteins, particularly the hydrophobe/amphiphile efflux-3 (HAE3) family represented by TIGR00921.
Pssm-ID: 274598 [Multi-domain] Cd Length: 862 Bit Score: 41.14 E-value: 4.67e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931595540 333 GLLGLVfAVVVILLFLL-SVRSTLVTAVSIPLSVMVALLALWTGDLSLNLLTLGALTIAVGRVVDDSIVVLENIKRhlay 411
Cdd:TIGR03480 718 FIYALV-AITVLLLLTLrRVRDVLLVLAPLLLAGLLTVAAMVLLGIPFNFANIIALPLLLGLGVDFGIYMVHRWRN---- 792
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931595540 412 gEGKQRAVLDGvrEVAGAVTASTLTTVAVFLPIAFVSgitGQLFSPFAVTVTVALLASLIVSLTIVPVLA 481
Cdd:TIGR03480 793 -GVDSGNLLQS--STARAVFFSALTTATAFGSLAVSS---HPGTASMGILLSLGLGLTLLCTLIFLPALL 856
|
|
| |
