|
Name |
Accession |
Description |
Interval |
E-value |
| ClpA |
COG0542 |
ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein ... |
1-796 |
0e+00 |
|
ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 440308 [Multi-domain] Cd Length: 836 Bit Score: 1354.75 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931484044 1 MRFDKFTQKAQEALSNAQEVLDEYNHQELDVEHIFLALLKQDDGLVPKILKRLDIMTEVVLRRLEGSLEIRPKVYGgAAA 80
Cdd:COG0542 1 MNFEKFTEKAQEALEAAQELARRLGHQEVEPEHLLLALLEQGEGLAAKLLRKLGVDLDALREELEEALGRLPKVSG-SSG 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931484044 81 QMYITPRTKKLLSLARAEAQRMNDEYVGSEHLFLAITEEREGETATLLREFGINKEKTYQALQSMRGSQRVTDQDAENKY 160
Cdd:COG0542 80 QPYLSPRLKRVLELAELEARKLGDEYISTEHLLLALLREGEGVAARILKKLGITLEALREALEELRGGSRVTSQNPESKT 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931484044 161 MALERFARDITALAKQGKLDPVIGRDDEIKRIVQVLSRRAKNNPVLIGDAGVGKTAIIEGLAQKIVDKNVPEILKDKRIL 240
Cdd:COG0542 160 PALDKYGRDLTELAREGKLDPVIGRDEEIRRVIQILSRRTKNNPVLIGEPGVGKTAIVEGLAQRIVNGDVPESLKDKRVL 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931484044 241 ALDMGALVAGSKYRGEFEERLKAVMDEIKKGKGEIILFIDELHTIVGAGAAEGAIDASNMLKPALARGELQCIGATTLNE 320
Cdd:COG0542 240 SLDLGALVAGAKYRGEFEERLKAVLDEVKKSEGNIILFIDELHTLVGAGGAEGAMDAANLLKPALARGELRCIGATTLDE 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931484044 321 YRKNVEKDAALERRFAPVYVGEPSVEDTIKILQGLKSRYESHHGVVIDQSAIEAAAKLSDRYITERYLPDKAIDLVDEAC 400
Cdd:COG0542 320 YRKYIEKDAALERRFQPVLVEEPSVEDTISILRGLKERYEAHHGVRITDEALVAAVRLSDRYITDRFLPDKAIDLIDEAA 399
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931484044 401 ARARIEVYSMPDNLKEMEKSLERLNDEGKQAV---DMRNYEKAAELRDESEKLQKEYRQKRGAWMKQRGIDDK------- 470
Cdd:COG0542 400 ARVRMEIDSKPEELDELERRLEQLEIEKEALKkeqDEASFERLAELRDELAELEEELEALKARWEAEKELIEEiqelkee 479
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931484044 471 --------------------------------VCADDIAHIVSTWTGIPVSRMMESEMDKLLKMEERIHMRLVDQEDAVV 518
Cdd:COG0542 480 leqrygkipelekelaeleeelaelapllreeVTEEDIAEVVSRWTGIPVGKLLEGEREKLLNLEEELHERVIGQDEAVE 559
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931484044 519 AVSDAIRRSRAGLKDPNRPIGSFIFLGPTGVGKTELSKSLAEFLFDTEEAMVRIDMTEYQEKHTVSRLIGAPPGYVGYEE 598
Cdd:COG0542 560 AVADAIRRSRAGLKDPNRPIGSFLFLGPTGVGKTELAKALAEFLFGDEDALIRIDMSEYMEKHSVSRLIGAPPGYVGYEE 639
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931484044 599 GGQLTEAVRRRPYRVILFDEFEKAHPDVFNILLQMLDDGRMTDGQGRTVDFKNTIIIMTSNLGSEVItQSLQDGRFDYEK 678
Cdd:COG0542 640 GGQLTEAVRRRPYSVVLLDEIEKAHPDVFNILLQVLDDGRLTDGQGRTVDFRNTIIIMTSNIGSELI-LDLAEDEPDYEE 718
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931484044 679 TKIDVNQILQRSVKPEFLNRVDEVIVFKPLEFDAIKGIVGRELNKVMKNISEFGYEIEFSDTVKDHLAHEGFDQVYGARP 758
Cdd:COG0542 719 MKEAVMEELKKHFRPEFLNRIDEIIVFHPLSKEELRKIVDLQLKRLRKRLAERGITLELTDAAKDFLAEKGYDPEYGARP 798
|
810 820 830
....*....|....*....|....*....|....*...
gi 931484044 759 LRRAIQRLVENPLSKAILAGKFKKGSRIKVDLEKGEVV 796
Cdd:COG0542 799 LKRAIQRELEDPLAEEILAGEIKEGDTITVDVDDGELV 836
|
|
| chaperone_ClpB |
TIGR03346 |
ATP-dependent chaperone ClpB; Members of this protein family are the bacterial ATP-dependent ... |
6-796 |
0e+00 |
|
ATP-dependent chaperone ClpB; Members of this protein family are the bacterial ATP-dependent chaperone ClpB. This protein belongs to the AAA family, ATPases associated with various cellular activities (pfam00004). This molecular chaperone does not act as a protease, but rather serves to disaggregate misfolded and aggregated proteins. [Protein fate, Protein folding and stabilization]
Pssm-ID: 274529 [Multi-domain] Cd Length: 850 Bit Score: 1169.73 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931484044 6 FTQKAQEALSNAQEVLDEYNHQELDVEHIFLALLKQDDGLVPKILKRLDIMTEVVLRRLEGSLEIRPKVyGGAAAQMYIT 85
Cdd:TIGR03346 1 LTEKFQEALQAAQSLALGRDHQQIEPEHLLKALLDQEGGLARPLLQKAGVNVGALRQALEKELERLPKV-SGPGGQVYLS 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931484044 86 PRTKKLLSLARAEAQRMNDEYVGSEHLFLAITEEReGETATLLREFGINKEKTYQALQSMRGSQRVTDQDAENKYMALER 165
Cdd:TIGR03346 80 PDLNRLLNLAEKLAQKRGDEFISSEHLLLALLDDK-GTLGKLLKEAGATADALEAAINAVRGGQKVTDANAEDQYEALEK 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931484044 166 FARDITALAKQGKLDPVIGRDDEIKRIVQVLSRRAKNNPVLIGDAGVGKTAIIEGLAQKIVDKNVPEILKDKRILALDMG 245
Cdd:TIGR03346 159 YARDLTERAREGKLDPVIGRDEEIRRTIQVLSRRTKNNPVLIGEPGVGKTAIVEGLAQRIVNGDVPEGLKNKRLLALDMG 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931484044 246 ALVAGSKYRGEFEERLKAVMDEIKKGKGEIILFIDELHTIVGAGAAEGAIDASNMLKPALARGELQCIGATTLNEYRKNV 325
Cdd:TIGR03346 239 ALIAGAKYRGEFEERLKAVLNEVTKSEGQIILFIDELHTLVGAGKAEGAMDAGNMLKPALARGELHCIGATTLDEYRKYI 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931484044 326 EKDAALERRFAPVYVGEPSVEDTIKILQGLKSRYESHHGVVIDQSAIEAAAKLSDRYITERYLPDKAIDLVDEACARARI 405
Cdd:TIGR03346 319 EKDAALERRFQPVFVDEPSVEDTISILRGLKERYEVHHGVRITDPAIVAAATLSHRYITDRFLPDKAIDLIDEAAARIRM 398
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931484044 406 EVYSMPDNLKEMEKSLERLNDEgKQAV----DMRNYEKAAELRDESEKLQKEYRQKRGAWMKQRG-----------ID-- 468
Cdd:TIGR03346 399 EIDSKPEELDELDRRIIQLEIE-REALkkekDEASKKRLEDLEKELADLEEEYAELEEQWKAEKAsiqgiqqikeeIEqv 477
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931484044 469 -----------------------------------------------DKVCADDIAHIVSTWTGIPVSRMMESEMDKLLK 501
Cdd:TIGR03346 478 rleleqaeregdlakaaelqygklpelekqlqaaeqklgeeqnrllrEEVTAEEIAEVVSRWTGIPVSKMLEGEREKLLH 557
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931484044 502 MEERIHMRLVDQEDAVVAVSDAIRRSRAGLKDPNRPIGSFIFLGPTGVGKTELSKSLAEFLFDTEEAMVRIDMTEYQEKH 581
Cdd:TIGR03346 558 MEEELHERVVGQDEAVEAVSDAIRRSRAGLSDPNRPIGSFLFLGPTGVGKTELAKALAEFLFDSEDAMVRIDMSEYMEKH 637
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931484044 582 TVSRLIGAPPGYVGYEEGGQLTEAVRRRPYRVILFDEFEKAHPDVFNILLQMLDDGRMTDGQGRTVDFKNTIIIMTSNLG 661
Cdd:TIGR03346 638 SVARLIGAPPGYVGYEEGGQLTEAVRRRPYSVVLFDEVEKAHPDVFNVLLQVLDDGRLTDGQGRTVDFRNTVIIMTSNLG 717
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931484044 662 SEVITQslQDGRFDYEKTKIDVNQILQRSVKPEFLNRVDEVIVFKPLEFDAIKGIVGRELNKVMKNISEFGYEIEFSDTV 741
Cdd:TIGR03346 718 SDFIQE--LAGGDDYEEMREAVMEVLRAHFRPEFLNRIDEIVVFHPLGREQIARIVEIQLGRLRKRLAERKITLELSDAA 795
|
810 820 830 840 850
....*....|....*....|....*....|....*....|....*....|....*
gi 931484044 742 KDHLAHEGFDQVYGARPLRRAIQRLVENPLSKAILAGKFKKGSRIKVDLEKGEVV 796
Cdd:TIGR03346 796 LDFLAEAGYDPVYGARPLKRAIQREIENPLAKKILAGEVAPGDTIRVDVEGGRLV 850
|
|
| clpC |
CHL00095 |
Clp protease ATP binding subunit |
3-792 |
0e+00 |
|
Clp protease ATP binding subunit
Pssm-ID: 214361 [Multi-domain] Cd Length: 821 Bit Score: 946.41 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931484044 3 FDKFTQKAQEALSNAQEVLDEYNHQELDVEHIFLALLKQDDGLVPKILKRLDIMTEVVlrRLEGSLEIRpKVYGGAAAQM 82
Cdd:CHL00095 2 FERFTEKAIKVIMLSQEEARRLGHNFVGTEQILLGLIGEGTGIAARALKSMGVTLKDA--RIEVEKIIG-RGTGFVAVEI 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931484044 83 YITPRTKKLLSLARAEAQRMNDEYVGSEHLFLAITEEREGETATLLREFGINKEKTYQALQSMRGSQR---VTDQDAENK 159
Cdd:CHL00095 79 PFTPRAKRVLEMSLEEARDLGHNYIGTEHLLLALLEEGEGVAARVLENLGVDLSKIRSLILNLIGEIIeaiLGAEQSRSK 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931484044 160 YMALERFARDITALAKQGKLDPVIGRDDEIKRIVQVLSRRAKNNPVLIGDAGVGKTAIIEGLAQKIVDKNVPEILKDKRI 239
Cdd:CHL00095 159 TPTLEEFGTNLTKEAIDGNLDPVIGREKEIERVIQILGRRTKNNPILIGEPGVGKTAIAEGLAQRIVNRDVPDILEDKLV 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931484044 240 LALDMGALVAGSKYRGEFEERLKAVMDEIKKgKGEIILFIDELHTIVGAGAAEGAIDASNMLKPALARGELQCIGATTLN 319
Cdd:CHL00095 239 ITLDIGLLLAGTKYRGEFEERLKRIFDEIQE-NNNIILVIDEVHTLIGAGAAEGAIDAANILKPALARGELQCIGATTLD 317
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931484044 320 EYRKNVEKDAALERRFAPVYVGEPSVEDTIKILQGLKSRYESHHGVVIDQSAIEAAAKLSDRYITERYLPDKAIDLVDEA 399
Cdd:CHL00095 318 EYRKHIEKDPALERRFQPVYVGEPSVEETIEILFGLRSRYEKHHNLSISDKALEAAAKLSDQYIADRFLPDKAIDLLDEA 397
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931484044 400 CARARIEVYSMPDNLKEMEKSLERLNDEGKQAVDMRNYEKAAELRDEseklQKEYRQKRGAWMK-------QRGIDDKVC 472
Cdd:CHL00095 398 GSRVRLINSRLPPAARELDKELREILKDKDEAIREQDFETAKQLRDR----EMEVRAQIAAIIQskkteeeKRLEVPVVT 473
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931484044 473 ADDIAHIVSTWTGIPVSRMMESEMDKLLKMEERIHMRLVDQEDAVVAVSDAIRRSRAGLKDPNRPIGSFIFLGPTGVGKT 552
Cdd:CHL00095 474 EEDIAEIVSAWTGIPVNKLTKSESEKLLHMEETLHKRIIGQDEAVVAVSKAIRRARVGLKNPNRPIASFLFSGPTGVGKT 553
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931484044 553 ELSKSLAEFLFDTEEAMVRIDMTEYQEKHTVSRLIGAPPGYVGYEEGGQLTEAVRRRPYRVILFDEFEKAHPDVFNILLQ 632
Cdd:CHL00095 554 ELTKALASYFFGSEDAMIRLDMSEYMEKHTVSKLIGSPPGYVGYNEGGQLTEAVRKKPYTVVLFDEIEKAHPDIFNLLLQ 633
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931484044 633 MLDDGRMTDGQGRTVDFKNTIIIMTSNLGSEVITQSLQDGRFDYEKTKID----------VNQILQRSVKPEFLNRVDEV 702
Cdd:CHL00095 634 ILDDGRLTDSKGRTIDFKNTLIIMTSNLGSKVIETNSGGLGFELSENQLSekqykrlsnlVNEELKQFFRPEFLNRLDEI 713
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931484044 703 IVFKPLEFDAIKGIVGRELNKVMKNISEFGYEIEFSDTVKDHLAHEGFDQVYGARPLRRAIQRLVENPLSKAILAGKFKK 782
Cdd:CHL00095 714 IVFRQLTKNDVWEIAEIMLKNLFKRLNEQGIQLEVTERIKTLLIEEGYNPLYGARPLRRAIMRLLEDPLAEEVLSFKIKP 793
|
810
....*....|
gi 931484044 783 GSRIKVDLEK 792
Cdd:CHL00095 794 GDIIIVDVND 803
|
|
| PRK10865 |
PRK10865 |
ATP-dependent chaperone ClpB; |
1-798 |
0e+00 |
|
ATP-dependent chaperone ClpB;
Pssm-ID: 182791 [Multi-domain] Cd Length: 857 Bit Score: 890.35 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931484044 1 MRFDKFTQKAQEALSNAQEVLDEYNHQELDVEHIFLALLKQDDGLVPKILKRLDIMTEVVLRRLEGSLEIRPKVYGgAAA 80
Cdd:PRK10865 1 MRLDRLTNKFQLALADAQSLALGHDNQFIEPLHLMSALLNQEGGSVRPLLTSAGINAGQLRTDINQALSRLPQVEG-TGG 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931484044 81 QMYITPRTKKLLSLARAEAQRMNDEYVGSEHLFLAITEEReGETATLLREFGINKEKTYQALQSMRGSQRVTDQDAENKY 160
Cdd:PRK10865 80 DVQPSQDLVRVLNLCDKLAQKRGDNFISSELFVLAALESR-GTLADILKAAGATTANITQAIEQMRGGESVNDQGAEDQR 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931484044 161 MALERFARDITALAKQGKLDPVIGRDDEIKRIVQVLSRRAKNNPVLIGDAGVGKTAIIEGLAQKIVDKNVPEILKDKRIL 240
Cdd:PRK10865 159 QALKKYTIDLTERAEQGKLDPVIGRDEEIRRTIQVLQRRTKNNPVLIGEPGVGKTAIVEGLAQRIINGEVPEGLKGRRVL 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931484044 241 ALDMGALVAGSKYRGEFEERLKAVMDEIKKGKGEIILFIDELHTIVGAGAAEGAIDASNMLKPALARGELQCIGATTLNE 320
Cdd:PRK10865 239 ALDMGALVAGAKYRGEFEERLKGVLNDLAKQEGNVILFIDELHTMVGAGKADGAMDAGNMLKPALARGELHCVGATTLDE 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931484044 321 YRKNVEKDAALERRFAPVYVGEPSVEDTIKILQGLKSRYESHHGVVIDQSAIEAAAKLSDRYITERYLPDKAIDLVDEAC 400
Cdd:PRK10865 319 YRQYIEKDAALERRFQKVFVAEPSVEDTIAILRGLKERYELHHHVQITDPAIVAAATLSHRYIADRQLPDKAIDLIDEAA 398
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931484044 401 ARARIEVYSMPDNLKEMEKSLERL-----------NDEGKQAVDMRNYEKAAELRDESE----------------KLQKE 453
Cdd:PRK10865 399 SSIRMQIDSKPEELDRLDRRIIQLkleqqalmkesDEASKKRLDMLNEELSDKERQYSEleeewkaekaslsgtqTIKAE 478
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931484044 454 YRQKRGAWMKQRGIDD-----------------------------------KVCADDIAHIVSTWTGIPVSRMMESEMDK 498
Cdd:PRK10865 479 LEQAKIAIEQARRVGDlarmselqygkipelekqlaaatqlegktmrllrnKVTDAEIAEVLARWTGIPVSRMLESEREK 558
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931484044 499 LLKMEERIHMRLVDQEDAVVAVSDAIRRSRAGLKDPNRPIGSFIFLGPTGVGKTELSKSLAEFLFDTEEAMVRIDMTEYQ 578
Cdd:PRK10865 559 LLRMEQELHHRVIGQNEAVEAVSNAIRRSRAGLSDPNRPIGSFLFLGPTGVGKTELCKALANFMFDSDDAMVRIDMSEFM 638
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931484044 579 EKHTVSRLIGAPPGYVGYEEGGQLTEAVRRRPYRVILFDEFEKAHPDVFNILLQMLDDGRMTDGQGRTVDFKNTIIIMTS 658
Cdd:PRK10865 639 EKHSVSRLVGAPPGYVGYEEGGYLTEAVRRRPYSVILLDEVEKAHPDVFNILLQVLDDGRLTDGQGRTVDFRNTVVIMTS 718
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931484044 659 NLGSEVITQSLqdGRFDYEKTKIDVNQILQRSVKPEFLNRVDEVIVFKPLEFDAIKGIVGRELNKVMKNISEFGYEIEFS 738
Cdd:PRK10865 719 NLGSDLIQERF--GELDYAHMKELVLGVVSHNFRPEFINRIDEVVVFHPLGEQHIASIAQIQLQRLYKRLEERGYEIHIS 796
|
810 820 830 840 850 860
....*....|....*....|....*....|....*....|....*....|....*....|
gi 931484044 739 DTVKDHLAHEGFDQVYGARPLRRAIQRLVENPLSKAILAGKFKKGSRIKVDLEKGEVVFK 798
Cdd:PRK10865 797 DEALKLLSENGYDPVYGARPLKRAIQQQIENPLAQQILSGELVPGKVIRLEVNDDRIVAV 856
|
|
| ClpA |
TIGR02639 |
ATP-dependent Clp protease ATP-binding subunit clpA; [Protein fate, Degradation of proteins, ... |
6-790 |
0e+00 |
|
ATP-dependent Clp protease ATP-binding subunit clpA; [Protein fate, Degradation of proteins, peptides, and glycopeptides]
Pssm-ID: 274241 [Multi-domain] Cd Length: 730 Bit Score: 748.39 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931484044 6 FTQKAQEALSNAQEVLDEYNHQELDVEHIFLALLKQDDGLvpKILKR----LDIMTEVVLRRLEGSLEIRPKVYGGAAAQ 81
Cdd:TIGR02639 1 ISEELERILSDALEEAKERRHEFVTLEHLLLALLDDNEAI--EILEEcggdVELLRKRLEDYLEENLPVIPEDIDEEPEQ 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931484044 82 myiTPRTKKLLSLARAEAQRMNDEYVGSEHLFLAITEEREGETATLLREFGINKEK---------TYQALQSMRGSQRVT 152
Cdd:TIGR02639 79 ---TVGVQRVIQRALLHVKSAGKKEIDIGDLLVALFDEEDSHASYFLKSQGITRLDilnyishgiSKDDGKDQLGEEAGK 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931484044 153 DQDAENKymALERFARDITALAKQGKLDPVIGRDDEIKRIVQVLSRRAKNNPVLIGDAGVGKTAIIEGLAQKIVDKNVPE 232
Cdd:TIGR02639 156 EEEKGQD--ALEKYTVDLTEKAKNGKIDPLIGREDELERTIQVLCRRKKNNPLLVGEPGVGKTAIVEGLALRIAEGKVPE 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931484044 233 ILKDKRILALDMGALVAGSKYRGEFEERLKAVMDEIKKGKGEIiLFIDELHTIVGAGA-AEGAIDASNMLKPALARGELQ 311
Cdd:TIGR02639 234 RLKNAKIYSLDMGTLLAGTKYRGDFEERLKAVVSEIEKEPNAI-LFIDEIHTIVGAGAtSGGSMDASNLLKPALSSGKIR 312
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931484044 312 CIGATTLNEYRKNVEKDAALERRFAPVYVGEPSVEDTIKILQGLKSRYESHHGVVIDQSAIEAAAKLSDRYITERYLPDK 391
Cdd:TIGR02639 313 CIGSTTYEEYKNHFEKDRALSRRFQKIDVGEPSIEETVKILKGLKEQYEEFHHVKYSDEALEAAVELSARYINDRFLPDK 392
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931484044 392 AIDLVDEACARARievysmpdnlkemekslerlndegkqavdmrnyekaaeLRDESEKlqkeyrqkrgawmkqrgiDDKV 471
Cdd:TIGR02639 393 AIDVIDEAGAAFR--------------------------------------LRPKAKK------------------KANV 416
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931484044 472 CADDIAHIVSTWTGIPVSRMMESEMDKLLKMEERIHMRLVDQEDAVVAVSDAIRRSRAGLKDPNRPIGSFIFLGPTGVGK 551
Cdd:TIGR02639 417 NVKDIENVVAKMAKIPVKTVSSDDREQLKNLEKNLKAKIFGQDEAIDQLVSAIKRSRAGLGDPNKPVGSFLFVGPTGVGK 496
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931484044 552 TELSKSLAEFLfdtEEAMVRIDMTEYQEKHTVSRLIGAPPGYVGYEEGGQLTEAVRRRPYRVILFDEFEKAHPDVFNILL 631
Cdd:TIGR02639 497 TELAKQLAEEL---GVHLLRFDMSEYMEKHTVSRLIGSPPGYVGFEQGGLLTDAVRKHPHCVLLLDEIEKAHPDIYNILL 573
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931484044 632 QMLDDGRMTDGQGRTVDFKNTIIIMTSNLGSEVITQSLQDgrFDYEKTKIDVNQILQRSVKPEFLNRVDEVIVFKPLEFD 711
Cdd:TIGR02639 574 QVMDYATLTDNNGRKADFRNVILIMTSNAGASEMSKPPIG--FGGENRESKSLKAIKKLFSPEFRNRLDAIIHFNDLSEE 651
|
730 740 750 760 770 780 790
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 931484044 712 AIKGIVGRELNKVMKNISEFGYEIEFSDTVKDHLAHEGFDQVYGARPLRRAIQRLVENPLSKAILAGKFKKGSRIKVDL 790
Cdd:TIGR02639 652 MAEKIVKKFLDELQDQLNEKNIELELTDDAKKYLAEKGYDEEFGARPLARVIQEEIKKPLSDEILFGKLKKGGSVKISL 730
|
|
| VI_ClpV1 |
TIGR03345 |
type VI secretion ATPase, ClpV1 family; Members of this protein family are homologs of ClpB, ... |
26-776 |
0e+00 |
|
type VI secretion ATPase, ClpV1 family; Members of this protein family are homologs of ClpB, an ATPase associated with chaperone-related functions. These ClpB homologs, designated ClpV1, are a key component of the bacterial pathogenicity-associated type VI secretion system. [Protein fate, Protein and peptide secretion and trafficking, Cellular processes, Pathogenesis]
Pssm-ID: 274528 [Multi-domain] Cd Length: 852 Bit Score: 718.26 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931484044 26 HQELDVEHIFLALLKQDDGLVPKILKRLDIMTEVVLRRLEGSLEIRPKvygGAAAQMYITPRTKKLL----SLARAEaqr 101
Cdd:TIGR03345 21 HPEVELEHWLLALLDQPDSDLAAILRHFGVDLGRLKADLARALDKLPR---GNTRTPVFSPHLVELLqeawLLASLE--- 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931484044 102 MNDEYVGSEHLFLAI--TEEREGETATLLREFG-INKEKTYQALQSMRG-----------SQRVTDQDAENKYMALERFA 167
Cdd:TIGR03345 95 LGDGRIRSGHLLLALltDPELRRLLGSISPELAkIDREALREALPALVEgsaeasaaaadAAPAGAAAGAAGTSALDQYT 174
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931484044 168 RDITALAKQGKLDPVIGRDDEIKRIVQVLSRRAKNNPVLIGDAGVGKTAIIEGLAQKIVDKNVPEILKDKRILALDMGAL 247
Cdd:TIGR03345 175 TDLTAQAREGKIDPVLGRDDEIRQMIDILLRRRQNNPILTGEAGVGKTAVVEGLALRIAAGDVPPALRNVRLLSLDLGLL 254
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931484044 248 VAGSKYRGEFEERLKAVMDEIKKGKGEIILFIDELHTIVGAGAAEGAIDASNMLKPALARGELQCIGATTLNEYRKNVEK 327
Cdd:TIGR03345 255 QAGASVKGEFENRLKSVIDEVKASPQPIILFIDEAHTLIGAGGQAGQGDAANLLKPALARGELRTIAATTWAEYKKYFEK 334
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931484044 328 DAALERRFAPVYVGEPSVEDTIKILQGLKSRYESHHGVVIDQSAIEAAAKLSDRYITERYLPDKAIDLVDEACARARIEV 407
Cdd:TIGR03345 335 DPALTRRFQVVKVEEPDEETAIRMLRGLAPVLEKHHGVLILDEAVVAAVELSHRYIPGRQLPDKAVSLLDTACARVALSQ 414
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931484044 408 YSMPDNLKEMEKSLERLNDE-----GKQAVDMRNYEKAAELRDESEKLQKEYRQKRGAWMKQRGI--------------- 467
Cdd:TIGR03345 415 NATPAALEDLRRRIAALELEldaleREAALGADHDERLAELRAELAALEAELAALEARWQQEKELveailalraeleada 494
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931484044 468 ----DDK---------------------------VCADDIAHIVSTWTGIPVSRMMESEMDKLLKMEERIHMRLVDQEDA 516
Cdd:TIGR03345 495 dapaDDDdalraqlaeleaalasaqgeeplvfpeVDAQAVAEVVADWTGIPVGRMVRDEIEAVLSLPDRLAERVIGQDHA 574
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931484044 517 VVAVSDAIRRSRAGLKDPNRPIGSFIFLGPTGVGKTELSKSLAEFLFDTEEAMVRIDMTEYQEKHTVSRLIGAPPGYVGY 596
Cdd:TIGR03345 575 LEAIAERIRTARAGLEDPRKPLGVFLLVGPSGVGKTETALALAELLYGGEQNLITINMSEFQEAHTVSRLKGSPPGYVGY 654
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931484044 597 EEGGQLTEAVRRRPYRVILFDEFEKAHPDVFNILLQMLDDGRMTDGQGRTVDFKNTIIIMTSNLGSEVITQSLQDG--RF 674
Cdd:TIGR03345 655 GEGGVLTEAVRRKPYSVVLLDEVEKAHPDVLELFYQVFDKGVMEDGEGREIDFKNTVILLTSNAGSDLIMALCADPetAP 734
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931484044 675 DYEKTKIDVNQILQRSVKPEFLNRVdEVIVFKPLEFDAIKGIVGRELNKVMKNISE-FGYEIEFSDTVKDHLAHEGFDQV 753
Cdd:TIGR03345 735 DPEALLEALRPELLKVFKPAFLGRM-TVIPYLPLDDDVLAAIVRLKLDRIARRLKEnHGAELVYSEALVEHIVARCTEVE 813
|
810 820
....*....|....*....|...
gi 931484044 754 YGARPLRRAIQRLVENPLSKAIL 776
Cdd:TIGR03345 814 SGARNIDAILNQTLLPELSRQIL 836
|
|
| clpA |
PRK11034 |
ATP-dependent Clp protease ATP-binding subunit; Provisional |
23-798 |
0e+00 |
|
ATP-dependent Clp protease ATP-binding subunit; Provisional
Pssm-ID: 236828 [Multi-domain] Cd Length: 758 Bit Score: 566.77 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931484044 23 EYNHQELDVEHIFLALLKQDDGLVPKILKRLDImteVVLRR-LEGSLEIRPKVYGGAAAQMYITPRT--KKLLSLARAEA 99
Cdd:PRK11034 19 EHRHEFMTVEHLLLALLSNPSAREALEACSVDL---VALRQeLEAFIEQTTPVLPASEEERDTQPTLsfQRVLQRAVFHV 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931484044 100 QRMNDEYVGSEHLFLAITEEREGETATLLRE-------------FGINKEKTYQALQSMRGSQRVTDQDAENKymaLERF 166
Cdd:PRK11034 96 QSSGRSEVTGANVLVAIFSEQESQAAYLLRKhevsrldvvnfisHGTRKDEPSQSSDPGSQPNSEEQAGGEER---MENF 172
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931484044 167 ARDITALAKQGKLDPVIGRDDEIKRIVQVLSRRAKNNPVLIGDAGVGKTAIIEGLAQKIVDKNVPEILKDKRILALDMGA 246
Cdd:PRK11034 173 TTNLNQLARVGGIDPLIGREKELERAIQVLCRRRKNNPLLVGESGVGKTAIAEGLAWRIVQGDVPEVMADCTIYSLDIGS 252
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931484044 247 LVAGSKYRGEFEERLKAVMDEIKKGKgEIILFIDELHTIVGAGAAEGA-IDASNMLKPALARGELQCIGATTLNEYRKNV 325
Cdd:PRK11034 253 LLAGTKYRGDFEKRFKALLKQLEQDT-NSILFIDEIHTIIGAGAASGGqVDAANLIKPLLSSGKIRVIGSTTYQEFSNIF 331
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931484044 326 EKDAALERRFAPVYVGEPSVEDTIKILQGLKSRYESHHGVVIDQSAIEAAAKLSDRYITERYLPDKAIDLVDEACARARI 405
Cdd:PRK11034 332 EKDRALARRFQKIDITEPSIEETVQIINGLKPKYEAHHDVRYTAKAVRAAVELAVKYINDRHLPDKAIDVIDEAGARARL 411
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931484044 406 evysMPDNlkemekslerlndegkqavdmrnyekaaelrdeseklqkeyRQKRgawmkqrgiddKVCADDIAHIVSTWTG 485
Cdd:PRK11034 412 ----MPVS-----------------------------------------KRKK-----------TVNVADIESVVARIAR 435
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931484044 486 IPVSRMMESEMDKLLKMEERIHMRLVDQEDAVVAVSDAIRRSRAGLKDPNRPIGSFIFLGPTGVGKTELSKSLAEFLfDT 565
Cdd:PRK11034 436 IPEKSVSQSDRDTLKNLGDRLKMLVFGQDKAIEALTEAIKMSRAGLGHEHKPVGSFLFAGPTGVGKTEVTVQLSKAL-GI 514
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931484044 566 EeaMVRIDMTEYQEKHTVSRLIGAPPGYVGYEEGGQLTEAVRRRPYRVILFDEFEKAHPDVFNILLQMLDDGRMTDGQGR 645
Cdd:PRK11034 515 E--LLRFDMSEYMERHTVSRLIGAPPGYVGFDQGGLLTDAVIKHPHAVLLLDEIEKAHPDVFNLLLQVMDNGTLTDNNGR 592
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931484044 646 TVDFKNTIIIMTSNLG-SEVITQSLQdgrFDYEKTKIDVNQILQRSVKPEFLNRVDEVIVFKPLEFDAIKGIVGRELNKV 724
Cdd:PRK11034 593 KADFRNVVLVMTTNAGvRETERKSIG---LIHQDNSTDAMEEIKKIFTPEFRNRLDNIIWFDHLSTDVIHQVVDKFIVEL 669
|
730 740 750 760 770 780 790
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 931484044 725 MKNISEFGYEIEFSDTVKDHLAHEGFDQVYGARPLRRAIQRLVENPLSKAILAGKFKKGSRIKVDLEKGEVVFK 798
Cdd:PRK11034 670 QAQLDQKGVSLEVSQEARDWLAEKGYDRAMGARPMARVIQDNLKKPLANELLFGSLVDGGQVTVALDKEKNELT 743
|
|
| RecA-like_ClpB_Hsp104-like |
cd19499 |
Chaperone protein ClpB/Hsp104 subfamily; Bacterial Caseinolytic peptidase B (ClpB) and ... |
498-705 |
8.63e-105 |
|
Chaperone protein ClpB/Hsp104 subfamily; Bacterial Caseinolytic peptidase B (ClpB) and eukaryotic Heat shock protein 104 (Hsp104) are ATP-dependent molecular chaperones and essential proteins of the heat-shock response. ClpB/Hsp104 ATPases, in concert with the DnaK/Hsp70 chaperone system, disaggregate and reactivate aggregated proteins. This RecA-like_ClpB_Hsp104_like subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.
Pssm-ID: 410907 [Multi-domain] Cd Length: 178 Bit Score: 319.12 E-value: 8.63e-105
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931484044 498 KLLKMEERIHMRLVDQEDAVVAVSDAIRRSRAGLKDPNRPIGSFIFLGPTGVGKTELSKSLAEFLFDTEEAMVRIDMTEY 577
Cdd:cd19499 1 KLLNLEERLHERVVGQDEAVKAVSDAIRRARAGLSDPNRPIGSFLFLGPTGVGKTELAKALAELLFGDEDNLIRIDMSEY 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931484044 578 QEKHTVSRLIGAPPGYVGYEEGGQLTEAVRRRPYRVILFDEFEKAHPDVFNILLQMLDDGRMTDGQGRTVDFKNTIIIMT 657
Cdd:cd19499 81 MEKHSVSRLIGAPPGYVGYTEGGQLTEAVRRKPYSVVLLDEIEKAHPDVQNLLLQVLDDGRLTDSHGRTVDFKNTIIIMT 160
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 931484044 658 SNlgsevitqslqdgRFdyektkidvnqilqrsvKPEFLNRVDEVIVF 705
Cdd:cd19499 161 SN-------------HF-----------------RPEFLNRIDEIVVF 178
|
|
| AAA_2 |
pfam07724 |
AAA domain (Cdc48 subfamily); This Pfam entry includes some of the AAA proteins not detected ... |
536-702 |
3.25e-91 |
|
AAA domain (Cdc48 subfamily); This Pfam entry includes some of the AAA proteins not detected by the pfam00004 model.
Pssm-ID: 400187 [Multi-domain] Cd Length: 168 Bit Score: 283.32 E-value: 3.25e-91
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931484044 536 RPIGSFIFLGPTGVGKTELSKSLAEFLFDTEEAMVRIDMTEYQEKHTVSRLIGAPPGYVGYEEGGQLTEAVRRRPYRVIL 615
Cdd:pfam07724 1 RPIGSFLFLGPTGVGKTELAKALAELLFGDERALIRIDMSEYMEEHSVSRLIGAPPGYVGYEEGGQLTEAVRRKPYSIVL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931484044 616 FDEFEKAHPDVFNILLQMLDDGRMTDGQGRTVDFKNTIIIMTSNLGSEVI-TQSLQDGRFDYEKTKIDVNQILQRSVKPE 694
Cdd:pfam07724 81 IDEIEKAHPGVQNDLLQILEGGTLTDKQGRTVDFKNTLFIMTGNFGSEKIsDASRLGDSPDYELLKEEVMDLLKKGFIPE 160
|
....*...
gi 931484044 695 FLNRVDEV 702
Cdd:pfam07724 161 FLGRLPII 168
|
|
| AAA_lid_9 |
pfam17871 |
AAA lid domain; This entry represents the alpha helical AAA+ lid domain that is found to the ... |
344-446 |
2.00e-42 |
|
AAA lid domain; This entry represents the alpha helical AAA+ lid domain that is found to the C-terminus of AAA domains.
Pssm-ID: 465544 [Multi-domain] Cd Length: 104 Bit Score: 149.56 E-value: 2.00e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931484044 344 SVEDTIKILQGLKSRYESHHGVVIDQSAIEAAAKLSDRYITERYLPDKAIDLVDEACARARIEVYSMPDNLKEMEKSLER 423
Cdd:pfam17871 1 SVEEAIEILRGLKPKYEKHHGVRISDEALEAAVKLSKRYITDRFLPDKAIDLLDEACARVRLSQESKPEELEDLERELAK 80
|
90 100
....*....|....*....|...
gi 931484044 424 LNDEGKQAVDMRNYEKAAELRDE 446
Cdd:pfam17871 81 LEIEKEALEREQDFEKAERLAKL 103
|
|
| ClpB_D2-small |
pfam10431 |
C-terminal, D2-small domain, of ClpB protein; This is the C-terminal domain of ClpB protein, ... |
708-788 |
2.90e-25 |
|
C-terminal, D2-small domain, of ClpB protein; This is the C-terminal domain of ClpB protein, referred to as the D2-small domain, and is a mixed alpha-beta structure. Compared with the D1-small domain (included in AAA, pfam00004) it lacks the long coiled-coil insertion, and instead of helix C4 contains a beta-strand (e3) that is part of a three stranded beta-pleated sheet. In Thermophilus the whole protein forms a hexamer with the D1-small and D2-small domains located on the outside of the hexamer, with the long coiled-coil being exposed on the surface. The D2-small domain is essential for oligomerization, forming a tight interface with the D2-large domain of a neighbouring subunit and thereby providing enough binding energy to stabilize the functional assembly. The domain is associated with two Clp_N, pfam02861, at the N-terminus as well as AAA, pfam00004 and AAA_2, pfam07724.
Pssm-ID: 463090 [Multi-domain] Cd Length: 81 Bit Score: 99.79 E-value: 2.90e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931484044 708 LEFDAIKGIVGRELNKVMKNISEFGYEIEFSDTVKDHLAHEGFDQVYGARPLRRAIQRLVENPLSKAILAGKFKKGSRIK 787
Cdd:pfam10431 1 LSKEELRKIVDLQLKELQKRLAERGITLELTDAAKDWLAEKGYDPEYGARPLRRAIQREIEDPLAEEILSGELKEGDTVR 80
|
.
gi 931484044 788 V 788
Cdd:pfam10431 81 V 81
|
|
| ClpB_D2-small |
smart01086 |
C-terminal, D2-small domain, of ClpB protein; This is the C-terminal domain of ClpB protein, ... |
711-797 |
1.55e-24 |
|
C-terminal, D2-small domain, of ClpB protein; This is the C-terminal domain of ClpB protein, referred to as the D2-small domain, and is a mixed alpha-beta structure. Compared with the D1-small domain (included in AAA) it lacks the long coiled-coil insertion, and instead of helix C4 contains a beta-strand (e3) that is part of a three stranded beta-pleated sheet. In Thermophilus the whole protein forms a hexamer with the D1-small and D2-small domains located on the outside of the hexamer, with the long coiled-coil being exposed on the surface. The D2-small domain is essential for oligomerisation, forming a tight interface with the D2-large domain of a neighbouring subunit and thereby providing enough binding energy to stabilise the functional assembly. The domain is associated with two Clp_N at the N-terminus as well as AAA and AAA_2.
Pssm-ID: 198154 [Multi-domain] Cd Length: 90 Bit Score: 97.90 E-value: 1.55e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931484044 711 DAIKGIVGRELNKVMKNISEFGYEIEFSDTVKDHLAHEGFDQVYGARPLRRAIQRLVENPLSKAILAGKFKKGSRIKVDL 790
Cdd:smart01086 4 EDLVRIVDLPLNALQKRLAEKGITLEFTDEALDWLAEKGYDPKYGARPLRRIIQRELEDPLAELILSGELKDGDTVVVDV 83
|
....*..
gi 931484044 791 EKGEVVF 797
Cdd:smart01086 84 DDGELVF 90
|
|
| AAA |
cd00009 |
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily ... |
183-335 |
8.38e-19 |
|
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC, RecA-like, VirD4-like, PilT-like, and SF1/2 helicases. Members of the AAA+ ATPases function as molecular chaperons, ATPase subunits of proteases, helicases, or nucleic-acid stimulated ATPases. The AAA+ proteins contain several distinct features in addition to the conserved alpha-beta-alpha core domain structure and the Walker A and B motifs of the P-loop NTPases.
Pssm-ID: 99707 [Multi-domain] Cd Length: 151 Bit Score: 83.73 E-value: 8.38e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931484044 183 IGRDDEIKRIVQVLSRRAKNNPVLIGDAGVGKTAIIEGLAQKIVDKNVPeilkdkrILALDMGALVAGSKYRGEFEERLK 262
Cdd:cd00009 1 VGQEEAIEALREALELPPPKNLLLYGPPGTGKTTLARAIANELFRPGAP-------FLYLNASDLLEGLVVAELFGHFLV 73
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 931484044 263 AVMDEIKKGKGEIILFIDELHTIvGAGAAEGAIDASNMLKPALA-RGELQCIGATTLNEYRKnveKDAALERRF 335
Cdd:cd00009 74 RLLFELAEKAKPGVLFIDEIDSL-SRGAQNALLRVLETLNDLRIdRENVRVIGATNRPLLGD---LDRALYDRL 143
|
|
| AAA |
cd00009 |
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily ... |
511-675 |
1.84e-16 |
|
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC, RecA-like, VirD4-like, PilT-like, and SF1/2 helicases. Members of the AAA+ ATPases function as molecular chaperons, ATPase subunits of proteases, helicases, or nucleic-acid stimulated ATPases. The AAA+ proteins contain several distinct features in addition to the conserved alpha-beta-alpha core domain structure and the Walker A and B motifs of the P-loop NTPases.
Pssm-ID: 99707 [Multi-domain] Cd Length: 151 Bit Score: 77.19 E-value: 1.84e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931484044 511 VDQEDAVVAVSDAIRRsraglkdpnRPIGSFIFLGPTGVGKTELSKSLAEFLFDTEEAMVRIDMTEYQEKHTVSRLIgap 590
Cdd:cd00009 1 VGQEEAIEALREALEL---------PPPKNLLLYGPPGTGKTTLARAIANELFRPGAPFLYLNASDLLEGLVVAELF--- 68
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931484044 591 pgyvGYEEGGQLTEAVRRRPYRVILFDEFEKAHPDVFNILLQMLDDGRMTdgqgrTVDFKNTIIIMTSNLGSEVITQSLQ 670
Cdd:cd00009 69 ----GHFLVRLLFELAEKAKPGVLFIDEIDSLSRGAQNALLRVLETLNDL-----RIDRENVRVIGATNRPLLGDLDRAL 139
|
....*
gi 931484044 671 DGRFD 675
Cdd:cd00009 140 YDRLD 144
|
|
| AAA_5 |
pfam07728 |
AAA domain (dynein-related subfamily); This Pfam entry includes some of the AAA proteins not ... |
540-674 |
1.18e-15 |
|
AAA domain (dynein-related subfamily); This Pfam entry includes some of the AAA proteins not detected by the pfam00004 model.
Pssm-ID: 400191 [Multi-domain] Cd Length: 135 Bit Score: 74.25 E-value: 1.18e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931484044 540 SFIFLGPTGVGKTELSKSLAEFLFDTEEAMVRI--DMTEyqekhtvSRLIGA--PPGYVGYEEGGQLTEAVRRRpyRVIL 615
Cdd:pfam07728 1 GVLLVGPPGTGKTELAERLAAALSNRPVFYVQLtrDTTE-------EDLFGRrnIDPGGASWVDGPLVRAAREG--EIAV 71
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 931484044 616 FDEFEKAHPDVFNILLQMLDDGRMTDGQGRT---VDFKNTIIIMTSN---LGSEVITQSLQDgRF 674
Cdd:pfam07728 72 LDEINRANPDVLNSLLSLLDERRLLLPDGGElvkAAPDGFRLIATMNpldRGLNELSPALRS-RF 135
|
|
| AAA |
smart00382 |
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ... |
542-665 |
4.90e-13 |
|
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.
Pssm-ID: 214640 [Multi-domain] Cd Length: 148 Bit Score: 67.40 E-value: 4.90e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931484044 542 IFLGPTGVGKTELSKSLAEFLFDTEEAMVRIDMTEYQEKHTVSRLIGAPPGYVGYEEGGQ----LTEAVRRRPYRVILFD 617
Cdd:smart00382 6 LIVGPPGSGKTTLARALARELGPPGGGVIYIDGEDILEEVLDQLLLIIVGGKKASGSGELrlrlALALARKLKPDVLILD 85
|
90 100 110 120
....*....|....*....|....*....|....*....|....*...
gi 931484044 618 EFEKAHPDVFNILLQMLDDGRMTDGQGRtvdFKNTIIIMTSNLGSEVI 665
Cdd:smart00382 86 EITSLLDAEQEALLLLLEELRLLLLLKS---EKNLTVILTTNDEKDLG 130
|
|
| Clp_N |
pfam02861 |
Clp amino terminal domain, pathogenicity island component; This short domain is found in one ... |
95-147 |
4.70e-11 |
|
Clp amino terminal domain, pathogenicity island component; This short domain is found in one or two copies at the amino terminus of ClpA and ClpB proteins from bacteria and eukaryotes. The function of these domains is uncertain but they may form a protein binding site. In many bacterial species, including E.coli, this region represents the N-terminus of one of the key components of the pathogenicity island complex that injects toxin from one bacterium into another.
Pssm-ID: 460724 [Multi-domain] Cd Length: 53 Bit Score: 58.30 E-value: 4.70e-11
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|...
gi 931484044 95 ARAEAQRMNDEYVGSEHLFLAITEEREGETATLLREFGINKEKTYQALQSMRG 147
Cdd:pfam02861 1 AQELARALGHQYIGTEHLLLALLEEDDGLAARLLKKAGVDLDALREAIEKLLG 53
|
|
| AAA |
pfam00004 |
ATPase family associated with various cellular activities (AAA); AAA family proteins often ... |
206-335 |
3.60e-10 |
|
ATPase family associated with various cellular activities (AAA); AAA family proteins often perform chaperone-like functions that assist in the assembly, operation, or disassembly of protein complexes.
Pssm-ID: 459627 [Multi-domain] Cd Length: 130 Bit Score: 58.37 E-value: 3.60e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931484044 206 LIGDAGVGKTAIIEGLAQKIvdknvpeilkDKRILALDMGALVagSKYRGEFEERLKAVMDEIKKgKGEIILFIDELHTI 285
Cdd:pfam00004 3 LYGPPGTGKTTLAKAVAKEL----------GAPFIEISGSELV--SKYVGESEKRLRELFEAAKK-LAPCVIFIDEIDAL 69
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*....
gi 931484044 286 VGAGAAEG---AIDASNMLKPAL-----ARGELQCIGATTlneyrkNVEK-DAALERRF 335
Cdd:pfam00004 70 AGSRGSGGdseSRRVVNQLLTELdgftsSNSKVIVIAATN------RPDKlDPALLGRF 122
|
|
| RecA-like_protease |
cd19481 |
proteases similar to RecA; RecA-like NTPases. This family includes the NTP binding domain of ... |
523-675 |
5.76e-09 |
|
proteases similar to RecA; RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.
Pssm-ID: 410889 [Multi-domain] Cd Length: 158 Bit Score: 55.75 E-value: 5.76e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931484044 523 AIRRSRAGLKDPNRPIGSFIFLGPTGVGKTELSKSLAEFLFDTeeaMVRIDMTEYQEKhtvsrligappgYVGYEEG--G 600
Cdd:cd19481 11 APRRGSRLRRYGLGLPKGILLYGPPGTGKTLLAKALAGELGLP---LIVVKLSSLLSK------------YVGESEKnlR 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931484044 601 QLTEAVRRRPYRVILFDEFEKAHPD------------VFNILLQMLDDGRMTDgqgrtvdfkNTIIIMTSNLGSEVITQS 668
Cdd:cd19481 76 KIFERARRLAPCILFIDEIDAIGRKrdssgesgelrrVLNQLLTELDGVNSRS---------KVLVIAATNRPDLLDPAL 146
|
....*..
gi 931484044 669 LQDGRFD 675
Cdd:cd19481 147 LRPGRFD 153
|
|
| SpoVK |
COG0464 |
AAA+-type ATPase, SpoVK/Ycf46/Vps4 family [Cell wall/membrane/envelope biogenesis, Cell cycle ... |
26-382 |
2.47e-07 |
|
AAA+-type ATPase, SpoVK/Ycf46/Vps4 family [Cell wall/membrane/envelope biogenesis, Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];
Pssm-ID: 440232 [Multi-domain] Cd Length: 397 Bit Score: 53.76 E-value: 2.47e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931484044 26 HQELDVEHIFLALLKQDDGLVPKILKRLDIMTEVVLRRLEGSLEIRPKVYGGAAAQMYITP--RTKKLLSLARAEAQRMN 103
Cdd:COG0464 1 LAELLALAVALALALLLLDDAALRLLLLLLLALAAALLLLLLLLLLLLLALLLVELLLLLLsgALAALLLLALLLLALLA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931484044 104 DEYVGSEHLFLAITEEREGETATLLREFGINKEKTYQALQSMRGSQRVTDQDAENKYMALERFARDITALAKQGKLDPVI 183
Cdd:COG0464 81 LLAALLSALELLLLGELLLLLLLLLLLLLLLLDLERALLELLRESAEALALAAPLVTYEDIGGLEEELLELREAILDDLG 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931484044 184 GRDD---EIKRIVQVLSRRAK-------NNP---VLIGDAGVGKTAIIEGLAqKIVDKNVpeilkdkriLALDMGALVag 250
Cdd:COG0464 161 GLEEvkeELRELVALPLKRPElreeyglPPPrglLLYGPPGTGKTLLARALA-GELGLPL---------IEVDLSDLV-- 228
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931484044 251 SKYRGEFEERLKAVMDEIKkGKGEIILFIDELHTIVGAGAAEGAIDAS---NMLKPALA--RGELQCIGATtlneYRKNv 325
Cdd:COG0464 229 SKYVGETEKNLREVFDKAR-GLAPCVLFIDEADALAGKRGEVGDGVGRrvvNTLLTEMEelRSDVVVIAAT----NRPD- 302
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*...
gi 931484044 326 EKDAALERRFA-PVYVGEPSVEDTIKILQGLKSRYESHHGVvidqsAIEAAAKLSDRY 382
Cdd:COG0464 303 LLDPALLRRFDeIIFFPLPDAEERLEIFRIHLRKRPLDEDV-----DLEELAEATEGL 355
|
|
| AAA |
smart00382 |
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ... |
201-335 |
9.33e-07 |
|
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.
Pssm-ID: 214640 [Multi-domain] Cd Length: 148 Bit Score: 49.29 E-value: 9.33e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931484044 201 KNNPVLIGDAGVGKTAIIEGLAQKIVDKNVPEILKD-----KRILALDMGALVAGSKYRGEFEERLKAVMDEIKKGKGeI 275
Cdd:smart00382 2 GEVILIVGPPGSGKTTLARALARELGPPGGGVIYIDgedilEEVLDQLLLIIVGGKKASGSGELRLRLALALARKLKP-D 80
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 931484044 276 ILFIDELHTIVGAG--AAEGAIDASNMLKPALARGELQCIGATTlneyRKNVEKDAALERRF 335
Cdd:smart00382 81 VLILDEITSLLDAEqeALLLLLEELRLLLLLKSEKNLTVILTTN----DEKDLGPALLRRRF 138
|
|
| Clp_N |
pfam02861 |
Clp amino terminal domain, pathogenicity island component; This short domain is found in one ... |
17-65 |
3.25e-06 |
|
Clp amino terminal domain, pathogenicity island component; This short domain is found in one or two copies at the amino terminus of ClpA and ClpB proteins from bacteria and eukaryotes. The function of these domains is uncertain but they may form a protein binding site. In many bacterial species, including E.coli, this region represents the N-terminus of one of the key components of the pathogenicity island complex that injects toxin from one bacterium into another.
Pssm-ID: 460724 [Multi-domain] Cd Length: 53 Bit Score: 44.82 E-value: 3.25e-06
10 20 30 40
....*....|....*....|....*....|....*....|....*....
gi 931484044 17 AQEVLDEYNHQELDVEHIFLALLKQDDGLVPKILKRLDIMTEVVLRRLE 65
Cdd:pfam02861 1 AQELARALGHQYIGTEHLLLALLEEDDGLAARLLKKAGVDLDALREAIE 49
|
|
| COG1223 |
COG1223 |
Predicted ATPase, AAA+ superfamily [General function prediction only]; |
510-779 |
9.69e-06 |
|
Predicted ATPase, AAA+ superfamily [General function prediction only];
Pssm-ID: 440836 [Multi-domain] Cd Length: 246 Bit Score: 47.96 E-value: 9.69e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931484044 510 LVDQEDAVVAVSDAIR-------RSRAGLKDPNRpigsFIFLGPTGVGKTELSKSLAEflfdteEAMVRIDMTEYqekht 582
Cdd:COG1223 4 VVGQEEAKKKLKLIIKelrrrenLRKFGLWPPRK----ILFYGPPGTGKTMLAEALAG------ELKLPLLTVRL----- 68
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931484044 583 vSRLIGAppgYVGyeEGG----QLTEAVRRRPYrVILFDEFE---------KAHPD---VFNILLQMLDDGRmtdgqgrt 646
Cdd:COG1223 69 -DSLIGS---YLG--ETArnlrKLFDFARRAPC-VIFFDEFDaiakdrgdqNDVGEvkrVVNALLQELDGLP-------- 133
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931484044 647 vdfKNTIIIMTSNLgsevitqslqdgrfdyektkidvNQILQRSVkpefLNRVDEVIVFKPLEFDAIKGIVGRelnkvmk 726
Cdd:COG1223 134 ---SGSVVIAATNH-----------------------PELLDSAL----WRRFDEVIEFPLPDKEERKEILEL------- 176
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*
gi 931484044 727 NISEFGYEIEFSDTVkdhLAH--EGFDQvygarplrRAIQRLVENPLSKAILAGK 779
Cdd:COG1223 177 NLKKFPLPFELDLKK---LAKklEGLSG--------ADIEKVLKTALKKAILEDR 220
|
|
| AAA_16 |
pfam13191 |
AAA ATPase domain; This family of domains contain a P-loop motif that is characteriztic of the ... |
181-283 |
2.65e-05 |
|
AAA ATPase domain; This family of domains contain a P-loop motif that is characteriztic of the AAA superfamily.
Pssm-ID: 433025 [Multi-domain] Cd Length: 167 Bit Score: 45.19 E-value: 2.65e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931484044 181 PVIGRDDEIKRIVQVLSRRAKNNP---VLIGDAGVGKTAIIEGLAQKIVDKNV----------------PEILKDKRILA 241
Cdd:pfam13191 1 RLVGREEELEQLLDALDRVRSGRPpsvLLTGEAGTGKTTLLRELLRALERDGGyflrgkcdenlpysplLEALTREGLLR 80
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 931484044 242 --LDMGALVAGSKYRGEFEERLKAVMDE------------------IKKGKGEIILFIDELH 283
Cdd:pfam13191 81 qlLDELESSLLEAWRAALLEALAPVPELpgdlaerlldlllrlldlLARGERPLVLVLDDLQ 142
|
|
| COG1223 |
COG1223 |
Predicted ATPase, AAA+ superfamily [General function prediction only]; |
179-285 |
4.07e-05 |
|
Predicted ATPase, AAA+ superfamily [General function prediction only];
Pssm-ID: 440836 [Multi-domain] Cd Length: 246 Bit Score: 46.03 E-value: 4.07e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931484044 179 LDPVIGRDDEIKRIVQVLS--------RRAKNNP----VLIGDAGVGKTAIIEGLAQKIvdkNVPeilkdkrILALDMGA 246
Cdd:COG1223 1 LDDVVGQEEAKKKLKLIIKelrrrenlRKFGLWPprkiLFYGPPGTGKTMLAEALAGEL---KLP-------LLTVRLDS 70
|
90 100 110
....*....|....*....|....*....|....*....
gi 931484044 247 LVagSKYRGEFEERLKAVMDEIKKGKGeiILFIDELHTI 285
Cdd:COG1223 71 LI--GSYLGETARNLRKLFDFARRAPC--VIFFDEFDAI 105
|
|
| McsA |
COG3880 |
Protein-arginine kinase activator protein McsA [Posttranslational modification, protein ... |
415-459 |
1.14e-04 |
|
Protein-arginine kinase activator protein McsA [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 443088 [Multi-domain] Cd Length: 173 Bit Score: 43.35 E-value: 1.14e-04
10 20 30 40
....*....|....*....|....*....|....*....|....*
gi 931484044 415 KEMEKSLERLNDEGKQAVDMRNYEKAAELRDESEKLQKEYRQKRG 459
Cdd:COG3880 129 LRIKREIEELKEELQEAVEKEEYEEAAELRDEIRELEKELGEEGE 173
|
|
| AAA_22 |
pfam13401 |
AAA domain; |
540-638 |
2.49e-04 |
|
AAA domain;
Pssm-ID: 379165 [Multi-domain] Cd Length: 129 Bit Score: 41.56 E-value: 2.49e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931484044 540 SFIFL-GPTGVGKTELSKSLAEFLFDTEEAMVRIDMTEYQEK----HTVSRLIGAPPGYVGYEEG--GQLTEAVRRRP-Y 611
Cdd:pfam13401 6 GILVLtGESGTGKTTLLRRLLEQLPEVRDSVVFVDLPSGTSPkdllRALLRALGLPLSGRLSKEEllAALQQLLLALAvA 85
|
90 100
....*....|....*....|....*..
gi 931484044 612 RVILFDEFEKAHPDVFNILLQMLDDGR 638
Cdd:pfam13401 86 VVLIIDEAQHLSLEALEELRDLLNLSS 112
|
|
| AAA |
pfam00004 |
ATPase family associated with various cellular activities (AAA); AAA family proteins often ... |
542-675 |
4.51e-04 |
|
ATPase family associated with various cellular activities (AAA); AAA family proteins often perform chaperone-like functions that assist in the assembly, operation, or disassembly of protein complexes.
Pssm-ID: 459627 [Multi-domain] Cd Length: 130 Bit Score: 41.04 E-value: 4.51e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931484044 542 IFLGPTGVGKTELSKSLAEFLFDTeeaMVRIDMTEyqekhTVSRLIGAPPGYVgyeegGQLTEAVRRRPYRVILFDEFEK 621
Cdd:pfam00004 2 LLYGPPGTGKTTLAKAVAKELGAP---FIEISGSE-----LVSKYVGESEKRL-----RELFEAAKKLAPCVIFIDEIDA 68
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 931484044 622 AHP-----------DVFNILLQMLDdgrmtdgqGRTVDFKNTIIIMTSNLgSEVITQSLQdGRFD 675
Cdd:pfam00004 69 LAGsrgsggdsesrRVVNQLLTELD--------GFTSSNSKVIVIAATNR-PDKLDPALL-GRFD 123
|
|
| SpoVK |
COG0464 |
AAA+-type ATPase, SpoVK/Ycf46/Vps4 family [Cell wall/membrane/envelope biogenesis, Cell cycle ... |
525-716 |
7.99e-04 |
|
AAA+-type ATPase, SpoVK/Ycf46/Vps4 family [Cell wall/membrane/envelope biogenesis, Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];
Pssm-ID: 440232 [Multi-domain] Cd Length: 397 Bit Score: 42.59 E-value: 7.99e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931484044 525 RRSRAGLkdpnRPIGSFIFLGPTGVGKTELSKSLAEFLfdtEEAMVRIDMteyqekhtvSRLIGappGYVGyEEGGQLTE 604
Cdd:COG0464 182 LREEYGL----PPPRGLLLYGPPGTGKTLLARALAGEL---GLPLIEVDL---------SDLVS---KYVG-ETEKNLRE 241
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931484044 605 AVR--RRPYRVILF-DEFEKAHPD-----------VFNILLQMLDDGRmtdgqgrtvdfKNTIIIMTSNlgsevitqslq 670
Cdd:COG0464 242 VFDkaRGLAPCVLFiDEADALAGKrgevgdgvgrrVVNTLLTEMEELR-----------SDVVVIAATN----------- 299
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 931484044 671 dgRFDyektKIDvnqilqrsvkPEFLNRVDEVIVFKPLEFDAIKGI 716
Cdd:COG0464 300 --RPD----LLD----------PALLRRFDEIIFFPLPDAEERLEI 329
|
|
| PRK05298 |
PRK05298 |
excinuclease ABC subunit UvrB; |
415-458 |
1.59e-03 |
|
excinuclease ABC subunit UvrB;
Pssm-ID: 235395 [Multi-domain] Cd Length: 652 Bit Score: 41.96 E-value: 1.59e-03
10 20 30 40
....*....|....*....|....*....|....*....|....
gi 931484044 415 KEMEKSLERLNDEGKQAVDMRNYEKAAELRDESEKLQKEYRQKR 458
Cdd:PRK05298 609 KELEKLIKELEKQMKEAAKNLEFEEAARLRDEIKELKEELLGLS 652
|
|
| UVR |
pfam02151 |
UvrB/uvrC motif; |
418-453 |
4.77e-03 |
|
UvrB/uvrC motif;
Pssm-ID: 308001 [Multi-domain] Cd Length: 36 Bit Score: 35.45 E-value: 4.77e-03
10 20 30
....*....|....*....|....*....|....*.
gi 931484044 418 EKSLERLNDEGKQAVDMRNYEKAAELRDESEKLQKE 453
Cdd:pfam02151 1 KKLIKELEEEMEEAAENEDFEKAAKLRDQINALKKQ 36
|
|
| COG3899 |
COG3899 |
Predicted ATPase [General function prediction only]; |
162-230 |
7.69e-03 |
|
Predicted ATPase [General function prediction only];
Pssm-ID: 443106 [Multi-domain] Cd Length: 1244 Bit Score: 39.84 E-value: 7.69e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 931484044 162 ALERFARDITALAKQGKLDPVIGRDDEIKRIVQVLSR--RAKNNPVLI-GDAGVGKTAIIEGLAQKIVDKNV 230
Cdd:COG3899 269 LLAAAAAGRRLLARRLIPQPLVGREAELAALLAALERarAGRGELVLVsGEAGIGKSRLVRELARRARARGG 340
|
|
| AAA_5 |
pfam07728 |
AAA domain (dynein-related subfamily); This Pfam entry includes some of the AAA proteins not ... |
205-335 |
8.22e-03 |
|
AAA domain (dynein-related subfamily); This Pfam entry includes some of the AAA proteins not detected by the pfam00004 model.
Pssm-ID: 400191 [Multi-domain] Cd Length: 135 Bit Score: 37.27 E-value: 8.22e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931484044 205 VLIGDAGVGKTAIIEGLAQKIVDKNV----------PEILKDKRILALDMGALVAGSKYRgEFEERLKAVMDEIKKGKGE 274
Cdd:pfam07728 3 LLVGPPGTGKTELAERLAAALSNRPVfyvqltrdttEEDLFGRRNIDPGGASWVDGPLVR-AAREGEIAVLDEINRANPD 81
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 931484044 275 IilfIDELHTIvgagaaegaIDASNMLKPALaRGELQC------IGATTLNEYRKNVEKDAALERRF 335
Cdd:pfam07728 82 V---LNSLLSL---------LDERRLLLPDG-GELVKAapdgfrLIATMNPLDRGLNELSPALRSRF 135
|
|
| UvrB |
COG0556 |
Excinuclease UvrABC helicase subunit UvrB [Replication, recombination and repair]; |
391-453 |
8.37e-03 |
|
Excinuclease UvrABC helicase subunit UvrB [Replication, recombination and repair];
Pssm-ID: 440322 [Multi-domain] Cd Length: 657 Bit Score: 39.61 E-value: 8.37e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931484044 391 KAI-DLVDEACARARIEVYSMPD------NLKEMEKSLERLNDEGKQAVDMRNYEKAAELRDESEKLQKE 453
Cdd:COG0556 588 KSIrDILEGTYEADEETEELVAEadaaklSKEELEKLIKELEKEMKEAAKNLEFEEAARLRDEIKELKKE 657
|
|
| RecA-like_protease |
cd19481 |
proteases similar to RecA; RecA-like NTPases. This family includes the NTP binding domain of ... |
187-285 |
8.73e-03 |
|
proteases similar to RecA; RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.
Pssm-ID: 410889 [Multi-domain] Cd Length: 158 Bit Score: 37.65 E-value: 8.73e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931484044 187 DEIKRIVQVLSRRAKNNPV---------LIGDAGVGKTAIIEGLAQKIvdkNVPEILkdkrilaLDMGALVagSKYRGEF 257
Cdd:cd19481 3 ASLREAVEAPRRGSRLRRYglglpkgilLYGPPGTGKTLLAKALAGEL---GLPLIV-------VKLSSLL--SKYVGES 70
|
90 100
....*....|....*....|....*...
gi 931484044 258 EERLKAVMDEIKKgKGEIILFIDELHTI 285
Cdd:cd19481 71 EKNLRKIFERARR-LAPCILFIDEIDAI 97
|
|
| |
