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Conserved domains on  [gi|931359085|gb|KPJ51314|]
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MAG: fructose-bisphosphate aldolase [candidate division Zixibacteria bacterium DG_27]

Protein Classification

Fba family protein( domain architecture ID 10785082)

Fba family protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Fba COG0191
Fructose/tagatose bisphosphate aldolase [Carbohydrate transport and metabolism]; Fructose ...
 26-350 2.99e-37

Fructose/tagatose bisphosphate aldolase [Carbohydrate transport and metabolism]; Fructose/tagatose bisphosphate aldolase is part of the Pathway/BioSystem: Glycolysis


:

Pssm-ID: 439961  Cd Length: 283  Bit Score: 135.22  E-value: 2.99e-37
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931359085  26 LLSSKPIFNALKDQACIVMACNTRIKHVIPGIMRAAKELEAVVAYELAKSECNlqggYTGmtP*DFFEAVI*YAERl*YT 105
Cdd:COG0191    2 LVSLKELLDKAKEGGYAVPAFNVNNLETLQAILEAAEELNSPVILQVSEGAAK----YAG--LEYLAAMVRAAAEE--AS 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931359085 106 EPFFIHGDHltVKSTKeeeiaeteeLLKAEIDAGYTSFAIDASFNELEDNITVTSRLAKHVVDLDMGLEVEVGEIksAGS 185
Cdd:COG0191   74 VPVALHLDH--GASFE---------LIKRAIDAGFTSVMIDGSHLPFEENIAITKEVVEYAHAAGVSVEAELGVV--GGE 140

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931359085 186 EGEI---------TTVEEATSFInglKENGIlpNLLAINNGSKHGNYlEGEKiFIDLERTGEIYEAIkddGVRIAQHGIT 256
Cdd:COG0191  141 EDGVdvddaealyTDPEEAAEFV---EETGV--DALAVAIGTVHGVY-KGEP-KLDFDRLKEIREAV---PVPLVLHGGS 210

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931359085 257 GTPPHLLGRFADYGIRKGNVGTEWQNIAHQGmptdlvdeMKKWAKEtgkdikfankqfKEEINDlPRKYLEKIADLAYQK 336
Cdd:COG0191  211 GVPDEEIREAIKLGVAKINIDTDLRLAFTAA--------VREYLAE------------NPDKYD-PRKYLKPAREAMKEV 269

                        330
                 ....*....|....
gi 931359085 337 AGEFLIAFRAKGTA 350
Cdd:COG0191  270 VKEKIRLFGSAGKA 283
 
Name Accession Description Interval E-value
Fba COG0191
Fructose/tagatose bisphosphate aldolase [Carbohydrate transport and metabolism]; Fructose ...
 26-350 2.99e-37

Fructose/tagatose bisphosphate aldolase [Carbohydrate transport and metabolism]; Fructose/tagatose bisphosphate aldolase is part of the Pathway/BioSystem: Glycolysis


Pssm-ID: 439961  Cd Length: 283  Bit Score: 135.22  E-value: 2.99e-37
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931359085  26 LLSSKPIFNALKDQACIVMACNTRIKHVIPGIMRAAKELEAVVAYELAKSECNlqggYTGmtP*DFFEAVI*YAERl*YT 105
Cdd:COG0191    2 LVSLKELLDKAKEGGYAVPAFNVNNLETLQAILEAAEELNSPVILQVSEGAAK----YAG--LEYLAAMVRAAAEE--AS 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931359085 106 EPFFIHGDHltVKSTKeeeiaeteeLLKAEIDAGYTSFAIDASFNELEDNITVTSRLAKHVVDLDMGLEVEVGEIksAGS 185
Cdd:COG0191   74 VPVALHLDH--GASFE---------LIKRAIDAGFTSVMIDGSHLPFEENIAITKEVVEYAHAAGVSVEAELGVV--GGE 140

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931359085 186 EGEI---------TTVEEATSFInglKENGIlpNLLAINNGSKHGNYlEGEKiFIDLERTGEIYEAIkddGVRIAQHGIT 256
Cdd:COG0191  141 EDGVdvddaealyTDPEEAAEFV---EETGV--DALAVAIGTVHGVY-KGEP-KLDFDRLKEIREAV---PVPLVLHGGS 210

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931359085 257 GTPPHLLGRFADYGIRKGNVGTEWQNIAHQGmptdlvdeMKKWAKEtgkdikfankqfKEEINDlPRKYLEKIADLAYQK 336
Cdd:COG0191  211 GVPDEEIREAIKLGVAKINIDTDLRLAFTAA--------VREYLAE------------NPDKYD-PRKYLKPAREAMKEV 269

                        330
                 ....*....|....
gi 931359085 337 AGEFLIAFRAKGTA 350
Cdd:COG0191  270 VKEKIRLFGSAGKA 283
F_bP_aldolase pfam01116
Fructose-bisphosphate aldolase class-II;
28-302 1.37e-23

Fructose-bisphosphate aldolase class-II;


Pssm-ID: 460071  Cd Length: 276  Bit Score: 98.25  E-value: 1.37e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931359085   28 SSKPIFNALKDQACIVMACNTRIKHVIPGIMRAAKELEAVVAYELAKSECNlqggYTGMTP*DFFEAVI*YAERl*YTEP 107
Cdd:pfam01116   2 NLKELLKKAKEGGYAVPAFNVNNLETVQAILEAAEEAKSPVILQVSPGAAA----KYAGGAEALAALVRAAAEA--AGVP 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931359085  108 FFIHGDHltvkstkeeeiAETEELLKAEIDAGYTSFAIDASFNELEDNITVTSRLAKHVVDLDMGLEVEVGEIksAGSEG 187
Cdd:pfam01116  76 VALHLDH-----------GASFELIKEAIEAGFTSVMIDGSHLPFEENIAITKEVVEYAHARGVSVEAELGRI--GGEED 142

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931359085  188 EI-------TTVEEATSFInglKENGIlpNLLAINNGSKHGNYLEGEKifIDLERTGEIYEAIkddGVRIAQHGITGTPP 260
Cdd:pfam01116 143 GVvvdeklyTDPEEAAEFV---EATGV--DALAVAIGNVHGVYKPGPK--LDFDRLKEIQEAV---PVPLVLHGGSGVPD 212

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....
gi 931359085  261 HLLGRFADYGIRKGNVGTEWQNIAHQGM--------PTDLV----DEMKKWAKE 302
Cdd:pfam01116 213 EDIRKAIKLGVCKINIDTDLQLAFTAAVreyppnkdPRKYLrpaeEAMKEVVKE 266
PRK08185 PRK08185
hypothetical protein; Provisional
 57-299 7.06e-15

hypothetical protein; Provisional


Pssm-ID: 181275  Cd Length: 283  Bit Score: 73.99  E-value: 7.06e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931359085  57 IMRAAKELEAVVAYELAKSECNLQGgytgmtp*DFFEAVI*YAERL*YtePFFIHGDHltvkstkeeeIAETEELLKAeI 136
Cdd:PRK08185  29 VVEEAEANNAPAIIAIHPNELDFLG-------DNFFAYVRERAKRSPV--PFVIHLDH----------GATIEDVMRA-I 88

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931359085 137 DAGYTSFAIDASFNELEDNITVTsrlaKHVVDLDMGL----EVEVGEIKSAG--SEGEITTV-----EEATSFINglkEN 205
Cdd:PRK08185  89 RCGFTSVMIDGSLLPYEENVALT----KEVVELAHKVgvsvEGELGTIGNTGtsIEGGVSEIiytdpEQAEDFVS---RT 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931359085 206 GIlpNLLAINNGSKHGNYLEGEKIFIDLERTGEIYEAIkddGVRIAQHGITGTPPHLLGRFADYGIRKGNVGTEWQNIAH 285
Cdd:PRK08185 162 GV--DTLAVAIGTAHGIYPKDKKPELQMDLLKEINERV---DIPLVLHGGSANPDAEIAESVQLGVGKINISSDMKYAFF 236

                        250
                 ....*....|....
gi 931359085 286 QGMPTDLVDEMKKW 299
Cdd:PRK08185 237 KKVREILSDNPSLY 250
 
Name Accession Description Interval E-value
Fba COG0191
Fructose/tagatose bisphosphate aldolase [Carbohydrate transport and metabolism]; Fructose ...
 26-350 2.99e-37

Fructose/tagatose bisphosphate aldolase [Carbohydrate transport and metabolism]; Fructose/tagatose bisphosphate aldolase is part of the Pathway/BioSystem: Glycolysis


Pssm-ID: 439961  Cd Length: 283  Bit Score: 135.22  E-value: 2.99e-37
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931359085  26 LLSSKPIFNALKDQACIVMACNTRIKHVIPGIMRAAKELEAVVAYELAKSECNlqggYTGmtP*DFFEAVI*YAERl*YT 105
Cdd:COG0191    2 LVSLKELLDKAKEGGYAVPAFNVNNLETLQAILEAAEELNSPVILQVSEGAAK----YAG--LEYLAAMVRAAAEE--AS 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931359085 106 EPFFIHGDHltVKSTKeeeiaeteeLLKAEIDAGYTSFAIDASFNELEDNITVTSRLAKHVVDLDMGLEVEVGEIksAGS 185
Cdd:COG0191   74 VPVALHLDH--GASFE---------LIKRAIDAGFTSVMIDGSHLPFEENIAITKEVVEYAHAAGVSVEAELGVV--GGE 140

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931359085 186 EGEI---------TTVEEATSFInglKENGIlpNLLAINNGSKHGNYlEGEKiFIDLERTGEIYEAIkddGVRIAQHGIT 256
Cdd:COG0191  141 EDGVdvddaealyTDPEEAAEFV---EETGV--DALAVAIGTVHGVY-KGEP-KLDFDRLKEIREAV---PVPLVLHGGS 210

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931359085 257 GTPPHLLGRFADYGIRKGNVGTEWQNIAHQGmptdlvdeMKKWAKEtgkdikfankqfKEEINDlPRKYLEKIADLAYQK 336
Cdd:COG0191  211 GVPDEEIREAIKLGVAKINIDTDLRLAFTAA--------VREYLAE------------NPDKYD-PRKYLKPAREAMKEV 269

                        330
                 ....*....|....
gi 931359085 337 AGEFLIAFRAKGTA 350
Cdd:COG0191  270 VKEKIRLFGSAGKA 283
F_bP_aldolase pfam01116
Fructose-bisphosphate aldolase class-II;
28-302 1.37e-23

Fructose-bisphosphate aldolase class-II;


Pssm-ID: 460071  Cd Length: 276  Bit Score: 98.25  E-value: 1.37e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931359085   28 SSKPIFNALKDQACIVMACNTRIKHVIPGIMRAAKELEAVVAYELAKSECNlqggYTGMTP*DFFEAVI*YAERl*YTEP 107
Cdd:pfam01116   2 NLKELLKKAKEGGYAVPAFNVNNLETVQAILEAAEEAKSPVILQVSPGAAA----KYAGGAEALAALVRAAAEA--AGVP 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931359085  108 FFIHGDHltvkstkeeeiAETEELLKAEIDAGYTSFAIDASFNELEDNITVTSRLAKHVVDLDMGLEVEVGEIksAGSEG 187
Cdd:pfam01116  76 VALHLDH-----------GASFELIKEAIEAGFTSVMIDGSHLPFEENIAITKEVVEYAHARGVSVEAELGRI--GGEED 142

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931359085  188 EI-------TTVEEATSFInglKENGIlpNLLAINNGSKHGNYLEGEKifIDLERTGEIYEAIkddGVRIAQHGITGTPP 260
Cdd:pfam01116 143 GVvvdeklyTDPEEAAEFV---EATGV--DALAVAIGNVHGVYKPGPK--LDFDRLKEIQEAV---PVPLVLHGGSGVPD 212

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....
gi 931359085  261 HLLGRFADYGIRKGNVGTEWQNIAHQGM--------PTDLV----DEMKKWAKE 302
Cdd:pfam01116 213 EDIRKAIKLGVCKINIDTDLQLAFTAAVreyppnkdPRKYLrpaeEAMKEVVKE 266
PRK08185 PRK08185
hypothetical protein; Provisional
 57-299 7.06e-15

hypothetical protein; Provisional


Pssm-ID: 181275  Cd Length: 283  Bit Score: 73.99  E-value: 7.06e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931359085  57 IMRAAKELEAVVAYELAKSECNLQGgytgmtp*DFFEAVI*YAERL*YtePFFIHGDHltvkstkeeeIAETEELLKAeI 136
Cdd:PRK08185  29 VVEEAEANNAPAIIAIHPNELDFLG-------DNFFAYVRERAKRSPV--PFVIHLDH----------GATIEDVMRA-I 88

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931359085 137 DAGYTSFAIDASFNELEDNITVTsrlaKHVVDLDMGL----EVEVGEIKSAG--SEGEITTV-----EEATSFINglkEN 205
Cdd:PRK08185  89 RCGFTSVMIDGSLLPYEENVALT----KEVVELAHKVgvsvEGELGTIGNTGtsIEGGVSEIiytdpEQAEDFVS---RT 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931359085 206 GIlpNLLAINNGSKHGNYLEGEKIFIDLERTGEIYEAIkddGVRIAQHGITGTPPHLLGRFADYGIRKGNVGTEWQNIAH 285
Cdd:PRK08185 162 GV--DTLAVAIGTAHGIYPKDKKPELQMDLLKEINERV---DIPLVLHGGSANPDAEIAESVQLGVGKINISSDMKYAFF 236

                        250
                 ....*....|....
gi 931359085 286 QGMPTDLVDEMKKW 299
Cdd:PRK08185 237 KKVREILSDNPSLY 250
PRK08610 PRK08610
fructose-bisphosphate aldolase; Reviewed
 26-347 6.55e-14

fructose-bisphosphate aldolase; Reviewed


Pssm-ID: 181501  Cd Length: 286  Bit Score: 71.17  E-value: 6.55e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931359085  26 LLSSKPIFNALKDQACIVMACNTRIKHVIPGIMRAAKELEAVVAYELAKSECNLQGGYtgMTP*DFFEAVI*yaERL*YT 105
Cdd:PRK08610   3 LVSMKEMLIDAKENGYAVGQYNLNNLEFTQAILEASQEENAPVILGVSEGAARYMSGF--YTVVKMVEGLM---HDLNIT 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931359085 106 EPFFIHGDHltvkstkeeeiAETEELLKAEIDAGYTSFAIDASFNELEDNITVTSRLAKHVVDLDMGLEVEVGEIksAGS 185
Cdd:PRK08610  78 IPVAIHLDH-----------GSSFEKCKEAIDAGFTSVMIDASHSPFEENVATTKKVVEYAHEKGVSVEAELGTV--GGQ 144

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931359085 186 EGEIttVEEATSFING------LKENGIlpNLLAINNGSKHGNYlEGEKI--FIDLERTGEiyeaikDDGVRIAQHGITG 257
Cdd:PRK08610 145 EDDV--VADGIIYADPkecqelVEKTGI--DALAPALGSVHGPY-KGEPKlgFKEMEEIGL------STGLPLVLHGGTG 213

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931359085 258 TPPHLLGRFADYGIRKGNVGTEWQnIAHQGMPTDLVDEmkkwaketgkdikfankqfKEEINDlPRKYL----EKIADLA 333
Cdd:PRK08610 214 IPTKDIQKAIPFGTAKINVNTENQ-IASAKAVRDVLNN-------------------DKEVYD-PRKYLgparEAIKETV 272

                        330
                 ....*....|....
gi 931359085 334 YQKAGEFLIAFRAK 347
Cdd:PRK08610 273 KGKIKEFGTSNRAK 286
PRK07709 PRK07709
fructose-bisphosphate aldolase; Provisional
 56-281 3.70e-12

fructose-bisphosphate aldolase; Provisional


Pssm-ID: 169068  Cd Length: 285  Bit Score: 66.23  E-value: 3.70e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931359085  56 GIMRAAKELEAVVAYELAKSECNLQGGYTgmTP*DFFEAVI*yaERL*YTEPFFIHGDHltvkstkeeeiAETEELLKAE 135
Cdd:PRK07709  33 AILAAAEEEKSPVILGVSEGAARHMTGFK--TVVAMVKALI---EEMNITVPVAIHLDH-----------GSSFEKCKEA 96

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931359085 136 IDAGYTSFAIDASFNELEDNITVTSRLAKHVVDLDMGLEVEVGEIksAGSEGEIttVEEATSFING------LKENGIlp 209
Cdd:PRK07709  97 IDAGFTSVMIDASHHPFEENVETTKKVVEYAHARNVSVEAELGTV--GGQEDDV--IAEGVIYADPaeckhlVEATGI-- 170

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 931359085 210 NLLAINNGSKHGNYLEGEKI-FIDLERtgeiyeaIKD-DGVRIAQHGITGTPPHLLGRFADYGIRKGNVGTEWQ 281
Cdd:PRK07709 171 DCLAPALGSVHGPYKGEPNLgFAEMEQ-------VRDfTGVPLVLHGGTGIPTADIEKAISLGTSKINVNTENQ 237
gatY PRK09195
tagatose-bisphosphate aldolase; Reviewed
 26-279 5.29e-12

tagatose-bisphosphate aldolase; Reviewed


Pssm-ID: 181690  Cd Length: 284  Bit Score: 65.53  E-value: 5.29e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931359085  26 LLSSKPIFNALKDQACIVMACNTRIKHVIPGIMRAAKELEAVVAyelaksecnLQGgytgmTP*DFFEAVI*Y------A 99
Cdd:PRK09195   3 LVSTKQMLNNAQRGGYAVPAFNIHNLETMQVVVETAAELHSPVI---------IAG-----TPGTFSYAGTEYllaivsA 68

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931359085 100 ERL*YTEPFFIHGDHltvkstkeeeiAETEELLKAEIDAGYTSFAIDASFNELEDNItvtsRLAKHVVDL----DMGLEV 175
Cdd:PRK09195  69 AAKQYHHPLALHLDH-----------HEKFDDIAQKVRSGVRSVMIDGSHLPFAQNI----SLVKEVVDFchrfDVSVEA 133

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931359085 176 EVGEIksAGSEGEI---------TTVEEATSFINglkENGIlpNLLAINNGSKHGNYLEGEKifIDLERTGEIYEAIKdd 246
Cdd:PRK09195 134 ELGRL--GGQEDDLqvdeadalyTDPAQAREFVE---ATGI--DSLAVAIGTAHGMYKGEPK--LDFDRLENIRQWVN-- 202

                        250       260       270
                 ....*....|....*....|....*....|...
gi 931359085 247 gVRIAQHGITGTPPHLLGRFADYGIRKGNVGTE 279
Cdd:PRK09195 203 -IPLVLHGASGLPTKDIQQTIKLGICKVNVATE 234
kbaY PRK12738
tagatose-bisphosphate aldolase subunit KbaY;
26-309 1.76e-11

tagatose-bisphosphate aldolase subunit KbaY;


Pssm-ID: 183711  Cd Length: 286  Bit Score: 63.90  E-value: 1.76e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931359085  26 LLSSKPIFNALKDQACIVMACNTRIKHVIPGIMRAAKELEAVVAyelaksecnLQGgytgmTP*DF----FEAV--I*YA 99
Cdd:PRK12738   3 IISTKYLLQDAQANGYAVPAFNIHNAETIQAILEVCSEMRSPVI---------LAG-----TPGTFkhiaLEEIyaLCSA 68

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931359085 100 ERL*YTEPFFIHGDHltvkstkeeeiAETEELLKAEIDAGYTSFAIDASFNELEDNItvtsRLAKHVVDL----DMGLEV 175
Cdd:PRK12738  69 YSTTYNMPLALHLDH-----------HESLDDIRRKVHAGVRSAMIDGSHFPFAENV----KLVKSVVDFchsqDCSVEA 133

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931359085 176 EVGEIksAGSEGEItTVEEATSFINGLKENGILPNL-----LAINNGSKHGNYLEGEKifIDLERTGEIYEAIKddgVRI 250
Cdd:PRK12738 134 ELGRL--GGVEDDM-SVDAESAFLTDPQEAKRFVELtgvdsLAVAIGTAHGLYSKTPK--IDFQRLAEIREVVD---VPL 205

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 931359085 251 AQHGITGTPPHLLGRFADYGIRKGNVGTEWQnIAhqgmptdLVDEMKKWAKET--GKDIKF 309
Cdd:PRK12738 206 VLHGASDVPDEFVRRTIELGVTKVNVATELK-IA-------FAGAVKAWFAENpqGNDPRY 258
gatY PRK12737
tagatose-bisphosphate aldolase subunit GatY;
83-327 3.28e-11

tagatose-bisphosphate aldolase subunit GatY;


Pssm-ID: 183710  Cd Length: 284  Bit Score: 63.17  E-value: 3.28e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931359085  83 YTGMtp*DFFEAVI*YAERl*YTEPFFIHGDHltvkstkeeeiAETEELLKAEIDAGYTSFAIDASFNELEDNITVTSRL 162
Cdd:PRK12737  56 YAGT---DYIVAIAEVAAR-KYNIPLALHLDH-----------HEDLDDIKKKVRAGIRSVMIDGSHLSFEENIAIVKEV 120

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931359085 163 AKHVVDLDMGLEVEVGeiKSAGSEGEI---------TTVEEATSFInglKENGIlpNLLAINNGSKHGNYLEGEKifIDL 233
Cdd:PRK12737 121 VEFCHRYDASVEAELG--RLGGQEDDLvvdekdamyTNPDAAAEFV---ERTGI--DSLAVAIGTAHGLYKGEPK--LDF 191

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931359085 234 ERTGEIYEAIKddgVRIAQHGITGTPPHLLGRFADYGIRKGNVGTEWQnIAHQgmptdlvDEMKKWAKEtgkdikfankq 313
Cdd:PRK12737 192 ERLAEIREKVS---IPLVLHGASGVPDEDVKKAISLGICKVNVATELK-IAFS-------DAVKKYFYE----------- 249

                        250
                 ....*....|....
gi 931359085 314 fKEEINDlPRKYLE 327
Cdd:PRK12737 250 -NPKAND-PRKYMT 261
PLN02858 PLN02858
fructose-bisphosphate aldolase
 107-305 3.67e-11

fructose-bisphosphate aldolase


Pssm-ID: 215463 [Multi-domain]  Cd Length: 1378  Bit Score: 64.87  E-value: 3.67e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931359085  107 PFFIHGDHLTVKStkeeeiaeteELLKAeIDAGYTSFAIDASFNELEDNITVTSRLAKHVVDLDMGLEVEVGEIksAGSE 186
Cdd:PLN02858 1171 PITVHFDHGTSKH----------ELLEA-LELGFDSVMVDGSHLSFTENISYTKSISSLAHSKGLMVEAELGRL--SGTE 1237

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931359085  187 ---------GEITTVEEATSFINglkENGIlpNLLAINNGSKHGNY-LEGEKIFIDLERtgEIYEAIKDDGVRIAQHGIT 256
Cdd:PLN02858 1238 dgltveeyeAKLTDVDQAKEFID---ETGI--DALAVCIGNVHGKYpASGPNLRLDLLK--ELRALSSKKGVLLVLHGAS 1310

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|...
gi 931359085  257 GTPPHLLGRFADYGIRKGNVGTEWQNIAHQGM----PTDLVDEMKKwAKETGK 305
Cdd:PLN02858 1311 GLPESLIKECIENGVRKFNVNTEVRTAYMEALsspkKTDLIDVMSA-AKEAMK 1362
PRK06806 PRK06806
class II aldolase;
54-278 3.15e-10

class II aldolase;


Pssm-ID: 180705  Cd Length: 281  Bit Score: 60.15  E-value: 3.15e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931359085  54 IPGIMRAAKELEAVVAYELAKSECNlqggytgMTP*DFFEAVI*YAERl*YTEPFFIHGDH-LTVKStkeeeiaeteelL 132
Cdd:PRK06806  31 VMGAIKAAEELNSPIILQIAEVRLN-------HSPLHLIGPLMVAAAK-QAKVPVAVHFDHgMTFEK------------I 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931359085 133 KAEIDAGYTSFAIDASFNELEDNITVTSRLAKHVVDLDMGLEVEVGEI--KSAGSEGE---ITTVEEATSFInglKENGI 207
Cdd:PRK06806  91 KEALEIGFTSVMFDGSHLPLEENIQKTKEIVELAKQYGATVEAEIGRVggSEDGSEDIemlLTSTTEAKRFA---EETDV 167

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 931359085 208 lpNLLAINNGSKHGNYLEGEKifIDLERTGEIYEAIKddgVRIAQHGITGTPPHLLGRFADYGIRKGNVGT 278
Cdd:PRK06806 168 --DALAVAIGNAHGMYNGDPN--LRFDRLQEINDVVH---IPLVLHGGSGISPEDFKKCIQHGIRKINVAT 231
PRK07315 PRK07315
fructose-bisphosphate aldolase; Provisional
 26-281 1.35e-08

fructose-bisphosphate aldolase; Provisional


Pssm-ID: 180926  Cd Length: 293  Bit Score: 55.28  E-value: 1.35e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931359085  26 LLSSKPIFNALKDQACIVMACNTRIKHVIPGIMRAAKELEAVVAYELAKSECNLQGGYTgmTP*DFFEAVI*yaERL*YT 105
Cdd:PRK07315   3 IVSAEKFVQAARDNGYAVGGFNTNNLEWTQAILRAAEAKKAPVLIQTSMGAAKYMGGYK--VCKNLIENLV---ESMGIT 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931359085 106 EPFFIHGDHLTVKSTKEEeiaeteellkaeIDAGYTSFAIDASFNELEDNItvtsRLAKHVVDL----DMGLEVEVGEIk 181
Cdd:PRK07315  78 VPVAIHLDHGHYEDALEC------------IEVGYTSIMFDGSHLPVEENL----KLAKEVVEKahakGISVEAEVGTI- 140

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931359085 182 sAGSE------GEITTVEEATSFInglkENGIlpNLLAINNGSKHGNYLEGEKiFIDLERTGEIYEAIKddGVRIAQHGI 255
Cdd:PRK07315 141 -GGEEdgiigkGELAPIEDAKAMV----ETGI--DFLAAGIGNIHGPYPENWE-GLDLDHLEKLTEAVP--GFPIVLHGG 210

                        250       260
                 ....*....|....*....|....*.
gi 931359085 256 TGTPPHLLGRFADYGIRKGNVGTEWQ 281
Cdd:PRK07315 211 SGIPDDQIQEAIKLGVAKVNVNTECQ 236
PRK15458 PRK15458
tagatose 6-phosphate aldolase subunit KbaZ; Provisional
 53-195 1.81e-06

tagatose 6-phosphate aldolase subunit KbaZ; Provisional


Pssm-ID: 185355  Cd Length: 426  Bit Score: 49.35  E-value: 1.81e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931359085  53 VIPGIMRAAKELEAVVAYELAKSECNLQGGYTGMTP*DFFEAVI*YAERL*Y-TEPFFIHGDHLT----VKSTKEEEIAE 127
Cdd:PRK15458  29 VLEAAIRYALANDSPLLIEATSNQVDQFGGYTGMTPADFRGFVCQLADSLNFpQEALILGGDHLGpnrwQNLPAAQAMAN 108

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931359085 128 TEELLKAEIDAGYTSFAIDASFNELEDNITVT--------SRLAK--------HVVDLDM----GLEVEV-GEIKSAGSE 186
Cdd:PRK15458 109 ADDLIKSYVAAGFKKIHLDCSMSCADDPIPLTdeivaeraARLAKiaeetcreHFGESDLvyviGTEVPVpGGAHETLSE 188


                 ....*....
gi 931359085 187 GEITTVEEA 195
Cdd:PRK15458 189 LAVTTPDAA 197
GatZ_KbaZ-like pfam08013
D-tagatose-1,6-bisphosphate aldolase subunit GatZ/KbaZ-like; Escherichia coli and other ...
 53-115 2.53e-06

D-tagatose-1,6-bisphosphate aldolase subunit GatZ/KbaZ-like; Escherichia coli and other enteric bacteria contain two closely related D-tagatose 1,6-bisphosphate (TagBP)-specific aldolases involved in catabolism of galactitol (genes gatY gatZ) and of N-acetyl-galactosamine and D-galactosamine (genes kbaY, kbaZ, also called agaY, agaZ). The catalytic subunits GatY/KbaY alone are sufficient to show aldolase activity and contain most or all of the residues that have been identified as essential in substrate/product recognition and catalysis for class II aldolases. However, these aldolases differ from other Class II aldolases (which are homodimeric enzymes) in that they require subunits GatZ/KbaZ for full activity and for good in vivo and in vitro stability. The Z subunits alone do not show any aldolase activity. This entry represents GatZ and KbaZ subunits. This entry also includes the D-tagatose 6-phosphate 4-epimerase Atu3167 from Agrobacterium fabrum which catalyzes the epimerization of D-tagatose 6-phosphate to D-fructose 6-phosphate. It should be noted that the previous suggestion of a tagatose 6P-kinase function for other members of this family has been debated.


Pssm-ID: 429785  Cd Length: 420  Bit Score: 49.07  E-value: 2.53e-06
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 931359085   53 VIPGIMRAAKELEAVVAYELAKSECNLQGGYTGMTP*DFFEAVI*YAERL*Y-TEPFFIHGDHL 115
Cdd:pfam08013  26 VIEAALRQALRDGSPVLIEATSNQVNQFGGYTGMTPADFRDFVLAIADRVGFpRERLILGGDHL 89
PRK05835 PRK05835
class II fructose-1,6-bisphosphate aldolase;
133-270 2.75e-06

class II fructose-1,6-bisphosphate aldolase;


Pssm-ID: 180280 [Multi-domain]  Cd Length: 307  Bit Score: 48.43  E-value: 2.75e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931359085 133 KAEIDAGYTSFAIDASFNELEDNITVTSRLAKHVVDLDMGLEVEVGEIksAGSEGEITTVEEATSFING------LKENG 206
Cdd:PRK05835  91 EKAVKAGFTSVMIDASHHAFEENLELTSKVVKMAHNAGVSVEAELGRL--MGIEDNISVDEKDAVLVNPkeaeqfVKESQ 168

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 931359085 207 IlpNLLAINNGSKHGNY-LEGEKIfIDLERTGEIYeaiKDDGVRIAQHGITGTPPHLLGRFADYG 270
Cdd:PRK05835 169 V--DYLAPAIGTSHGAFkFKGEPK-LDFERLQEVK---RLTNIPLVLHGASAIPDDVRKSYLDAG 227
PRK15052 PRK15052
tagatose-bisphosphate aldolase subunit GatZ;
53-195 7.60e-06

tagatose-bisphosphate aldolase subunit GatZ;


Pssm-ID: 237889  Cd Length: 421  Bit Score: 47.53  E-value: 7.60e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931359085  53 VIPGIMRAAKELEAVVAYELAKSECNLQGGYTGMTP*DFFEAVI*YAERL*YT-EPFFIHGDHLT----VKSTKEEEIAE 127
Cdd:PRK15052  26 VIEAALAFDLNSTRKVLIEATSNQVNQFGGYTGMTPADFREFVYGIADKVGFPrERIILGGDHLGpncwQQEPADAAMEK 105

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 931359085 128 TEELLKAEIDAGYTSFAIDASFNELEDNI-----TVTSRLA--------------KHVVDLDMGLEVEV--GEIKSAGSE 186
Cdd:PRK15052 106 SVELVKAYVRAGFSKIHLDASMSCADDPIplapeTVAERAAvlcqaaesvatdcqREQLSYVIGTEVPVpgGEASAIQSV 185


                 ....*....
gi 931359085 187 gEITTVEEA 195
Cdd:PRK15052 186 -HVTRVEDA 193
GatZ COG4573
Tagatose-1,6-bisphosphate aldolase non-catalytic subunit AgaZ/GatZ [Carbohydrate transport and ...
 53-115 4.75e-05

Tagatose-1,6-bisphosphate aldolase non-catalytic subunit AgaZ/GatZ [Carbohydrate transport and metabolism];


Pssm-ID: 443630  Cd Length: 423  Bit Score: 44.80  E-value: 4.75e-05
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 931359085  53 VIPGIMRAAKELEAVVayeLAKSECNlQ----GGYTGMTP*DFFEAVI*YAERL*Y-TEPFFIHGDHL 115
Cdd:COG4573   28 VIEAALRRALEDGSPV---LIEATSN-QvnqfGGYTGMTPADFRDFVLGIADEVGFpRERLILGGDHL 91
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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