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Conserved domains on  [gi|929654438|dbj|BAA32300|]
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KIAA0455 protein [Homo sapiens]

Protein Classification

PAP2 phosphatase family protein( domain architecture ID 10130187)

type 2 phosphatidic acid phosphatase (PAP2) family protein similar to phospholipid phosphatase that catalyzes the conversion of phosphatidic acid to diacylglycerol

CATH:  1.20.144.10
EC:  3.1.3.-
Gene Ontology:  GO:0042577|GO:0046839|GO:0008610
PubMed:  9122162|12447906|9260289
SCOP:  3001110|4001226

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PAP2_wunen cd03384
PAP2, wunen subfamily. Most likely a family of membrane associated phosphatidic acid ...
 174-323 3.69e-68

PAP2, wunen subfamily. Most likely a family of membrane associated phosphatidic acid phosphatases. Wunen is a drosophila protein expressed in the central nervous system, which provides repellent activity towards primordial germ cells (PGCs), controls the survival of PGCs and is essential in the migration process of these cells towards the somatic gonadal precursors.


:

Pssm-ID: 239479  Cd Length: 150  Bit Score: 221.35  E-value: 3.69e-68
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 929654438 174 RAVRFVGVHVFGLCSTALITDIIQLSTGYQAPYFLTVCKPNYTSLNVSCKEnSYIVEDICSGSDLTVINSGRKSFPSQHA 253
Cdd:cd03384    1 RLYRFVGVFLFGLFATQLLTDLGKYVTGRLRPHFLDVCKPNYTDLTCSLDH-QYIADCTCCTGDPDLIREARLSFPSGHA 79

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 929654438 254 TLAAFAAVYVSMYFNSTLTD-SSKLLKPLLVFTFIICGIICGLTRITQYKNHPVDVYCGFLIGGGIALYLG 323
Cdd:cd03384   80 SLSMYAAVFLALYLQARLKLrGSRLLRPLLQFLLLALALYVGLSRISDYKHHWSDVLAGALLGSVIALFLV 150
 
Name Accession Description Interval E-value
PAP2_wunen cd03384
PAP2, wunen subfamily. Most likely a family of membrane associated phosphatidic acid ...
 174-323 3.69e-68

PAP2, wunen subfamily. Most likely a family of membrane associated phosphatidic acid phosphatases. Wunen is a drosophila protein expressed in the central nervous system, which provides repellent activity towards primordial germ cells (PGCs), controls the survival of PGCs and is essential in the migration process of these cells towards the somatic gonadal precursors.


Pssm-ID: 239479  Cd Length: 150  Bit Score: 221.35  E-value: 3.69e-68
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 929654438 174 RAVRFVGVHVFGLCSTALITDIIQLSTGYQAPYFLTVCKPNYTSLNVSCKEnSYIVEDICSGSDLTVINSGRKSFPSQHA 253
Cdd:cd03384    1 RLYRFVGVFLFGLFATQLLTDLGKYVTGRLRPHFLDVCKPNYTDLTCSLDH-QYIADCTCCTGDPDLIREARLSFPSGHA 79

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 929654438 254 TLAAFAAVYVSMYFNSTLTD-SSKLLKPLLVFTFIICGIICGLTRITQYKNHPVDVYCGFLIGGGIALYLG 323
Cdd:cd03384   80 SLSMYAAVFLALYLQARLKLrGSRLLRPLLQFLLLALALYVGLSRISDYKHHWSDVLAGALLGSVIALFLV 150
PAP2 pfam01569
PAP2 superfamily; This family includes the enzyme type 2 phosphatidic acid phosphatase (PAP2), ...
 183-322 4.54e-14

PAP2 superfamily; This family includes the enzyme type 2 phosphatidic acid phosphatase (PAP2), Glucose-6-phosphatase EC:3.1.3.9, Phosphatidylglycerophosphatase B EC:3.1.3.27 and bacterial acid phosphatase EC:3.1.3.2. The family also includes a variety of haloperoxidases that function by oxidising halides in the presence of hydrogen peroxide to form the corresponding hypohalous acids.


Pssm-ID: 426329 [Multi-domain]  Cd Length: 124  Bit Score: 69.37  E-value: 4.54e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 929654438  183 VFGLCSTALITDIIQLSTGYQAPYFLTVCKPNYTslnvsckensyivedicsgsDLTVINSGRKSFPSQHATLAAFAAVY 262
Cdd:pfam01569   3 LLALALAGLLSSVLKDYFGRPRPFFLLLEGGLVP--------------------APSTLPGLGYSFPSGHSATAFALALL 62

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 929654438  263 VSMYFNSTLtdssKLLKPLLVFTFIICGIICGLTRITQYKNHPVDVYCGFLIGGGIALYL 322
Cdd:pfam01569  63 LALLLRRLR----KIVRVLLALLLLVLALLVGLSRLYLGVHFPSDVLAGALIGILLALLV 118
acidPPc smart00014
Acid phosphatase homologues;
183-322 3.90e-13

Acid phosphatase homologues;


Pssm-ID: 214471 [Multi-domain]  Cd Length: 116  Bit Score: 66.60  E-value: 3.90e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 929654438   183 VFGLCSTALITDIIQLSTGYQAPYFLtvckpnytslnvsckensyIVEDICSGSDLTVINSGRKSFPSQHATLAAFAAVY 262
Cdd:smart00014   1 ALLAVVSQLFNGVIKNYFGRPRPFFL-------------------SIGDACCTPNFLLTLEAGYSFPSGHTAFAFAFALF 61

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 929654438   263 VSMYFNSTLTdsskllKPLLVFTFIICGIICGLTRITQYKNHPVDVYCGFLIGGGIALYL 322
Cdd:smart00014  62 LLLYLPARAG------RKLLIFLLLLLALVVGFSRVYLGAHWPSDVLAGSLLGILIAAVL 115
PLN02715 PLN02715
lipid phosphate phosphatase
 183-366 9.91e-09

lipid phosphate phosphatase


Pssm-ID: 178317 [Multi-domain]  Cd Length: 327  Bit Score: 57.76  E-value: 9.91e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 929654438 183 VFGLCSTALITDIIQLSTGYQAPYFLTVCKPNYTSLNVSckensyIVEDICSGSDLTViNSGRKSFPSQHATLAAFAAVY 262
Cdd:PLN02715 129 LFAVLITGVITDSIKVATGRPRPNFYWRCFPDGKELYDA------LGGVICHGKAAEV-KEGHKSFPSGHTSWSFAGLTF 201

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 929654438 263 VSMYFNSTL---TDSSKLLKPLLVFTFIICGIICGLTRITQYKNHPVDVYCGFLIGGGIALYL--------------GLY 325
Cdd:PLN02715 202 LSLYLSGKIkafNGEGHVAKLCLVIFPLLAACLVGISRVDDYWHHWQDVFAGALIGILVAAFCyrqfypnpyheegwGPY 281

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*.
gi 929654438 326 AVgnFLPSDE-----SMFQHRDALRSLTdLNQDPNRLLSAKNGSSS 366
Cdd:PLN02715 282 AY--FKAAQErgvpvASSQNGDALRAMS-LQMDSTSLENMESGTST 324
PgpB COG0671
Membrane-associated phospholipid phosphatase [Lipid transport and metabolism]; ...
 247-322 1.21e-04

Membrane-associated phospholipid phosphatase [Lipid transport and metabolism]; Membrane-associated phospholipid phosphatase is part of the Pathway/BioSystem: Phospholipid biosynthesis


Pssm-ID: 440435 [Multi-domain]  Cd Length: 189  Bit Score: 43.88  E-value: 1.21e-04
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 929654438 247 SFPSQHATLAAFAAVYVSMYFNSTLtdsskLLKPLLVFTFIIcgiicGLTRITQYKNHPVDVYCGFLIGGGIALYL 322
Cdd:COG0671  118 SFPSGHAAAAFALALVLALLLPRRW-----LAALLLALALLV-----GLSRVYLGVHYPSDVLAGALLGLAIALLL 183
 
Name Accession Description Interval E-value
PAP2_wunen cd03384
PAP2, wunen subfamily. Most likely a family of membrane associated phosphatidic acid ...
 174-323 3.69e-68

PAP2, wunen subfamily. Most likely a family of membrane associated phosphatidic acid phosphatases. Wunen is a drosophila protein expressed in the central nervous system, which provides repellent activity towards primordial germ cells (PGCs), controls the survival of PGCs and is essential in the migration process of these cells towards the somatic gonadal precursors.


Pssm-ID: 239479  Cd Length: 150  Bit Score: 221.35  E-value: 3.69e-68
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 929654438 174 RAVRFVGVHVFGLCSTALITDIIQLSTGYQAPYFLTVCKPNYTSLNVSCKEnSYIVEDICSGSDLTVINSGRKSFPSQHA 253
Cdd:cd03384    1 RLYRFVGVFLFGLFATQLLTDLGKYVTGRLRPHFLDVCKPNYTDLTCSLDH-QYIADCTCCTGDPDLIREARLSFPSGHA 79

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 929654438 254 TLAAFAAVYVSMYFNSTLTD-SSKLLKPLLVFTFIICGIICGLTRITQYKNHPVDVYCGFLIGGGIALYLG 323
Cdd:cd03384   80 SLSMYAAVFLALYLQARLKLrGSRLLRPLLQFLLLALALYVGLSRISDYKHHWSDVLAGALLGSVIALFLV 150
PAP2_containing_1_like cd03390
PAP2, subfamily similar to human phosphatidic_acid_phosphatase_type_2_domain_containing_1. ...
 107-321 2.78e-23

PAP2, subfamily similar to human phosphatidic_acid_phosphatase_type_2_domain_containing_1. Most likely membrane-associated phosphatidic acid phosphatases. Plant members of this group are constitutively expressed in many tissues and exhibit both diacylglycerol pyrophosphate phosphatase activity as well as phosphatidate (PA) phosphatase activity, they may have a more generic housekeeping role in lipid metabolism.


Pssm-ID: 239484 [Multi-domain]  Cd Length: 193  Bit Score: 98.06  E-value: 2.78e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 929654438 107 SLSMPYIEptQEAIPFLMLLSLAFAGPAITImvgegILYCCLSKRRNGVGlepninaggcnFNSFLrravrfvgVHVFGL 186
Cdd:cd03390    2 SISYPFAE--SETVPTWLLVIISVGIPLLVI-----ILISLFFRRSLWDL-----------HTSLL--------GLLLSV 55

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 929654438 187 CSTALITDIIQLSTGYQAPYFLTVCKPNYTSlnvscKENSYIVEDICSGSDLTVINSGRKSFPSQHATLAAFAAVYVSMY 266
Cdd:cd03390   56 SLNGVITNVLKNYAGRPRPDFLARCFPDGGT-----PSDTLVGIDICCTGDPGVLKEGRKSFPSGHSSFAFAGLGFLSLY 130

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 929654438 267 FNSTLT---DSSKLLKPLLVFTFIICGIICGLTRITQYKNHPVDVYCGFLIGGGIALY 321
Cdd:cd03390  131 LAGKLHifdPRGSSWRLLLALLPLLLAILVAVSRTRDYRHHFSDVIAGSLIGLIIAYL 188
PAP2_like cd01610
PAP2_like proteins, a super-family of histidine phosphatases and vanadium haloperoxidases, ...
 175-322 1.36e-18

PAP2_like proteins, a super-family of histidine phosphatases and vanadium haloperoxidases, includes type 2 phosphatidic acid phosphatase or lipid phosphate phosphatase (LPP), Glucose-6-phosphatase, Phosphatidylglycerophosphatase B and bacterial acid phosphatase, vanadium chloroperoxidases, vanadium bromoperoxidases, and several other mostly uncharacterized subfamilies. Several members of this superfamily have been predicted to be transmembrane proteins.


Pssm-ID: 238813 [Multi-domain]  Cd Length: 122  Bit Score: 82.12  E-value: 1.36e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 929654438 175 AVRFVGVHVFGLCSTALITDIIQLSTGYQAPYFLTVCKPNYtslnvsckensyivedicsgsDLTVINSGRKSFPSQHAT 254
Cdd:cd01610    1 RRLLALLLLLALLAGLLLTGVLKYLFGRPRPYFLLRCGPDG---------------------DPLLLTEGGYSFPSGHAA 59

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 929654438 255 LAAFAAVYVSMYFNStltdssKLLKPLLVFTFIICGIICGLTRITQYKNHPVDVYCGFLIGGGIALYL 322
Cdd:cd01610   60 FAFALALFLALLLPR------RLLRLLLGLLLLLLALLVGLSRVYLGVHYPSDVLAGALLGILVALLV 121
PAP2 pfam01569
PAP2 superfamily; This family includes the enzyme type 2 phosphatidic acid phosphatase (PAP2), ...
 183-322 4.54e-14

PAP2 superfamily; This family includes the enzyme type 2 phosphatidic acid phosphatase (PAP2), Glucose-6-phosphatase EC:3.1.3.9, Phosphatidylglycerophosphatase B EC:3.1.3.27 and bacterial acid phosphatase EC:3.1.3.2. The family also includes a variety of haloperoxidases that function by oxidising halides in the presence of hydrogen peroxide to form the corresponding hypohalous acids.


Pssm-ID: 426329 [Multi-domain]  Cd Length: 124  Bit Score: 69.37  E-value: 4.54e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 929654438  183 VFGLCSTALITDIIQLSTGYQAPYFLTVCKPNYTslnvsckensyivedicsgsDLTVINSGRKSFPSQHATLAAFAAVY 262
Cdd:pfam01569   3 LLALALAGLLSSVLKDYFGRPRPFFLLLEGGLVP--------------------APSTLPGLGYSFPSGHSATAFALALL 62

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 929654438  263 VSMYFNSTLtdssKLLKPLLVFTFIICGIICGLTRITQYKNHPVDVYCGFLIGGGIALYL 322
Cdd:pfam01569  63 LALLLRRLR----KIVRVLLALLLLVLALLVGLSRLYLGVHFPSDVLAGALIGILLALLV 118
acidPPc smart00014
Acid phosphatase homologues;
183-322 3.90e-13

Acid phosphatase homologues;


Pssm-ID: 214471 [Multi-domain]  Cd Length: 116  Bit Score: 66.60  E-value: 3.90e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 929654438   183 VFGLCSTALITDIIQLSTGYQAPYFLtvckpnytslnvsckensyIVEDICSGSDLTVINSGRKSFPSQHATLAAFAAVY 262
Cdd:smart00014   1 ALLAVVSQLFNGVIKNYFGRPRPFFL-------------------SIGDACCTPNFLLTLEAGYSFPSGHTAFAFAFALF 61

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 929654438   263 VSMYFNSTLTdsskllKPLLVFTFIICGIICGLTRITQYKNHPVDVYCGFLIGGGIALYL 322
Cdd:smart00014  62 LLLYLPARAG------RKLLIFLLLLLALVVGFSRVYLGAHWPSDVLAGSLLGILIAAVL 115
PLN02715 PLN02715
lipid phosphate phosphatase
 183-366 9.91e-09

lipid phosphate phosphatase


Pssm-ID: 178317 [Multi-domain]  Cd Length: 327  Bit Score: 57.76  E-value: 9.91e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 929654438 183 VFGLCSTALITDIIQLSTGYQAPYFLTVCKPNYTSLNVSckensyIVEDICSGSDLTViNSGRKSFPSQHATLAAFAAVY 262
Cdd:PLN02715 129 LFAVLITGVITDSIKVATGRPRPNFYWRCFPDGKELYDA------LGGVICHGKAAEV-KEGHKSFPSGHTSWSFAGLTF 201

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 929654438 263 VSMYFNSTL---TDSSKLLKPLLVFTFIICGIICGLTRITQYKNHPVDVYCGFLIGGGIALYL--------------GLY 325
Cdd:PLN02715 202 LSLYLSGKIkafNGEGHVAKLCLVIFPLLAACLVGISRVDDYWHHWQDVFAGALIGILVAAFCyrqfypnpyheegwGPY 281

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*.
gi 929654438 326 AVgnFLPSDE-----SMFQHRDALRSLTdLNQDPNRLLSAKNGSSS 366
Cdd:PLN02715 282 AY--FKAAQErgvpvASSQNGDALRAMS-LQMDSTSLENMESGTST 324
PLN02731 PLN02731
Putative lipid phosphate phosphatase
 168-315 4.84e-08

Putative lipid phosphate phosphatase


Pssm-ID: 178332  Cd Length: 333  Bit Score: 55.42  E-value: 4.84e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 929654438 168 FNSFLRRAVRFVGVHVFGLC----STALITDIIQLSTGYQAPYFLTVCKPNYTSLNVSckensyIVEDICSGsDLTVINS 243
Cdd:PLN02731 104 FIYFRRRDVYDLHHAVLGLLysvlVTAVLTDAIKNAVGRPRPDFFWRCFPDGKALYDS------LGDVICHG-DKSVIRE 176

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 929654438 244 GRKSFPSQHATLAAFAAVYVSMYFNSTLT---DSSKLLKPLLVFTFIICGIICGLTRITQYKNHPVDVYCGFLIG 315
Cdd:PLN02731 177 GHKSFPSGHTSWSFSGLGFLSLYLSGKIQafdGKGHVAKLCIVILPLLFAALVGISRVDDYWHHWQDVFAGGLLG 251
PLN02250 PLN02250
lipid phosphate phosphatase
 183-321 5.89e-08

lipid phosphate phosphatase


Pssm-ID: 215139  Cd Length: 314  Bit Score: 55.32  E-value: 5.89e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 929654438 183 VFGLCSTALITDIIQLSTGYQAPYFLTVCKPNYTSLNVSCKENSyivedICSGsDLTVINSGRKSFPSQHATLAAFAAVY 262
Cdd:PLN02250 104 LFSVLITGVITDAIKDAVGRPRPDFFWRCFPDGKGVFHPVTTDV-----LCTG-AKSVIKEGHKSFPSGHTSWSFAGLGF 177

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 929654438 263 VSMYFNSTL---TDSSKLLKPLLVFTFIICGIICGLTRITQYKNHPVDVYCGFLIGGGIALY 321
Cdd:PLN02250 178 LSLYLSGKIrvfDRRGHVAKLCIVFLPLLVAALVGVSRVDDYWHHWQDVFAGALIGLTVASF 239
PAP2_lipid_A_1_phosphatase cd03389
PAP2_like proteins, Lipid A 1-phosphatase subfamily. Lipid A 1-phosphatase, or LpxE from ...
 247-325 1.51e-05

PAP2_like proteins, Lipid A 1-phosphatase subfamily. Lipid A 1-phosphatase, or LpxE from Francisella novicida selectively dephosphorylates lipid A at the 1-position. Lipid A is the membrane-anchor component of lipopolysaccharides (LPS), the major constituents of the outer membrane in many gram-negative bacteria.


Pssm-ID: 239483  Cd Length: 186  Bit Score: 46.16  E-value: 1.51e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 929654438 247 SFPSQHAT--LAAFAAVYvsmyfnstltdsskLLKPLLVFTFIICGIICGLTRITQYKNHPVDVYCGFLIGGGIALYLGL 324
Cdd:cd03389  119 SFPSGHSAtaGAAAAALA--------------LLFPRYRWAFILLALLIAFSRVIVGAHYPSDVIAGSLLGAVTALALYQ 184


                 .
gi 929654438 325 Y 325
Cdd:cd03389  185 R 185
PAP2_containing_2_like cd03391
PAP2, subfamily similar to human phosphatidic_acid_phosphatase_type_2_domain_containing_2. ...
 247-315 1.14e-04

PAP2, subfamily similar to human phosphatidic_acid_phosphatase_type_2_domain_containing_2. PAP2 is a super-family of phosphatases and haloperoxidases. This subgroup, which is specific to eukaryota, lacks functional characterization and may act as a membrane-associated phosphatidic acid phosphatase.


Pssm-ID: 239485 [Multi-domain]  Cd Length: 159  Bit Score: 43.08  E-value: 1.14e-04
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 929654438 247 SFPSQHATLAAFaaVYVSMYFNSTLTDSskLLKPLLVFTFIIcgiicGLTRITQYKNHPVDVYCGFLIG 315
Cdd:cd03391   92 SFPSGHASRAAF--VARFLLNHLVLAVP--LRVLLVLWATVV-----GISRVLLGRHHVLDVLAGAFLG 151
PgpB COG0671
Membrane-associated phospholipid phosphatase [Lipid transport and metabolism]; ...
 247-322 1.21e-04

Membrane-associated phospholipid phosphatase [Lipid transport and metabolism]; Membrane-associated phospholipid phosphatase is part of the Pathway/BioSystem: Phospholipid biosynthesis


Pssm-ID: 440435 [Multi-domain]  Cd Length: 189  Bit Score: 43.88  E-value: 1.21e-04
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 929654438 247 SFPSQHATLAAFAAVYVSMYFNSTLtdsskLLKPLLVFTFIIcgiicGLTRITQYKNHPVDVYCGFLIGGGIALYL 322
Cdd:COG0671  118 SFPSGHAAAAFALALVLALLLPRRW-----LAALLLALALLV-----GLSRVYLGVHYPSDVLAGALLGLAIALLL 183
PAP2_like_4 cd03395
PAP2_like_4 proteins. PAP2 is a super-family of phosphatases and haloperoxidases. This ...
 237-324 5.54e-04

PAP2_like_4 proteins. PAP2 is a super-family of phosphatases and haloperoxidases. This subgroup, which is specific to bacteria, lacks functional characterization and may act as a membrane-associated lipid phosphatase.


Pssm-ID: 239489  Cd Length: 177  Bit Score: 41.48  E-value: 5.54e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 929654438 237 DLTVINSGRK-SFPSQHATLAAFAAVYVSMYFNStltdsskllKPLLVFTFIICgIICGLTRITQYKNHPVDVYCGFLIG 315
Cdd:cd03395   94 LVVLGDQGGSySFASSHAANSFALALFIWLFFRR---------GLFSPVLLLWA-LLVGYSRVYVGVHYPGDVIAGALIG 163


                 ....*....
gi 929654438 316 GGIALYLGL 324
Cdd:cd03395  164 IISGLLFYL 172
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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