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Conserved domains on  [gi|928476047|gb|ALE85775|]
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FAD-linked oxidoreductase [Pseudonocardia sp. HH130629-09]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
GG-red-SF super family cl37033
geranylgeranyl reductase family; This model represents a subfamily which includes ...
 16-322 8.91e-63

geranylgeranyl reductase family; This model represents a subfamily which includes geranylgeranyl reductases involved in chlorophyll and bacteriochlorophyll biosynthesis as well as other related enzymes which may also act on geranylgeranyl groups or related substrates. [Biosynthesis of cofactors, prosthetic groups, and carriers, Chlorophyll and bacteriochlorphyll]


The actual alignment was detected with superfamily member TIGR02032:

Pssm-ID: 273936 [Multi-domain]  Cd Length: 295  Bit Score: 204.48  E-value: 8.91e-63
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928476047   16 DVLVVGAGPAGSATAAWAARHGLDVVLADSATFPRDKACGDGLTPRAIAELGHLGLGAWVDshgTNRGLRAHGFGQVLEL 95
Cdd:TIGR02032   2 DVVVVGAGPAGASAAYRLADKGLRVLLLEKKSFPRYKPCGGALSPRALEELDLPGELIVNL---VRGARFFSPNGDSVEI 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928476047   96 PWPGGSlpahGSAIPRTELDAGIRRVALEAGATPMEDAKAVDVTFSGGRVDSVVFDDGRSVRCRRLVVADGARSTLGRVL 175
Cdd:TIGR02032  79 PIETEL----AYVIDRDAFDEQLAERAQEAGAELRLGTRVLDVEIHDDRVVVIVRGSEGTVTAKIVIGADGSRSIVAKKL 154

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928476047  176 GrEWHQDTAYGVAARGYVTSgrHADPWISSHLELRGEADEVLAGYGWLFPLNDGRVNIGVGTLATdrrPANIKLRGLIDH 255
Cdd:TIGR02032 155 G-LKKEPREYGVAARAEVEM--PDEEVDEDFVEVYIDRGIVPGGYGWVFPKGDGTANVGVGSRSA---EEGEDPKKYLKD 228

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 928476047  256 YAnARRAEWELGPKVElVRSALLPMGGAVSGVAGPNWALVGDAAGCVNPLNGEGIDYGLETGRLVAE 322
Cdd:TIGR02032 229 FL-ARRPELKDAETVE-VCGALIPIGRPDEKLVRGNVLLVGDAAGHVNPLTGEGIYYAMRSGDIAAE 293
 
Name Accession Description Interval E-value
GG-red-SF TIGR02032
geranylgeranyl reductase family; This model represents a subfamily which includes ...
 16-322 8.91e-63

geranylgeranyl reductase family; This model represents a subfamily which includes geranylgeranyl reductases involved in chlorophyll and bacteriochlorophyll biosynthesis as well as other related enzymes which may also act on geranylgeranyl groups or related substrates. [Biosynthesis of cofactors, prosthetic groups, and carriers, Chlorophyll and bacteriochlorphyll]


Pssm-ID: 273936 [Multi-domain]  Cd Length: 295  Bit Score: 204.48  E-value: 8.91e-63
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928476047   16 DVLVVGAGPAGSATAAWAARHGLDVVLADSATFPRDKACGDGLTPRAIAELGHLGLGAWVDshgTNRGLRAHGFGQVLEL 95
Cdd:TIGR02032   2 DVVVVGAGPAGASAAYRLADKGLRVLLLEKKSFPRYKPCGGALSPRALEELDLPGELIVNL---VRGARFFSPNGDSVEI 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928476047   96 PWPGGSlpahGSAIPRTELDAGIRRVALEAGATPMEDAKAVDVTFSGGRVDSVVFDDGRSVRCRRLVVADGARSTLGRVL 175
Cdd:TIGR02032  79 PIETEL----AYVIDRDAFDEQLAERAQEAGAELRLGTRVLDVEIHDDRVVVIVRGSEGTVTAKIVIGADGSRSIVAKKL 154

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928476047  176 GrEWHQDTAYGVAARGYVTSgrHADPWISSHLELRGEADEVLAGYGWLFPLNDGRVNIGVGTLATdrrPANIKLRGLIDH 255
Cdd:TIGR02032 155 G-LKKEPREYGVAARAEVEM--PDEEVDEDFVEVYIDRGIVPGGYGWVFPKGDGTANVGVGSRSA---EEGEDPKKYLKD 228

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 928476047  256 YAnARRAEWELGPKVElVRSALLPMGGAVSGVAGPNWALVGDAAGCVNPLNGEGIDYGLETGRLVAE 322
Cdd:TIGR02032 229 FL-ARRPELKDAETVE-VCGALIPIGRPDEKLVRGNVLLVGDAAGHVNPLTGEGIYYAMRSGDIAAE 293
FixC COG0644
Dehydrogenase (flavoprotein) [Energy production and conversion];
35-339 2.73e-49

Dehydrogenase (flavoprotein) [Energy production and conversion];


Pssm-ID: 440409 [Multi-domain]  Cd Length: 281  Bit Score: 168.99  E-value: 2.73e-49
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928476047  35 RHGLDVVLADSATFPRDKACGDGLTPRAIAELGHLGLGAWVDSHGTNRGLRAHGfGQVLELPWPGGslpaHGSAIPRTEL 114
Cdd:COG0644   14 RAGLSVLLLEKGSFPGDKICGGGLLPRALEELEPLGLDEPLERPVRGARFYSPG-GKSVELPPGRG----GGYVVDRARF 88

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928476047 115 DAGIRRVALEAGATPMEDAKAVDVTFSGGRVdSVVFDDGRSVRCRRLVVADGARSTLGRVLG----REWHQDTAYGVAAR 190
Cdd:COG0644   89 DRWLAEQAEEAGAEVRTGTRVTDVLRDDGRV-VVRTGDGEEIRADYVVDADGARSLLARKLGlkrrSDEPQDYALAIKEH 167

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928476047 191 GYVTSGRHADPWISSHLELRGEADevlaGYGWLFPLNDGRVNIGVgtlatdrrpaniklrglidhyanarraewelgpkv 270
Cdd:COG0644  168 WELPPLEGVDPGAVEFFFGEGAPG----GYGWVFPLGDGRVSVGI----------------------------------- 208

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 928476047 271 elvrsallPMGGAVSGVAGPNWALVGDAAGCVNPLNGEGIDYGLETGRLVAELLASGADLDRAWPATLR 339
Cdd:COG0644  209 --------PLGGPRPRLVGDGVLLVGDAAGFVDPLTGEGIHLAMKSGRLAAEAIAEALEGGDFSAEALA 269
FAD_binding_3 pfam01494
FAD binding domain; This domain is involved in FAD binding in a number of enzymes.
 15-188 1.21e-08

FAD binding domain; This domain is involved in FAD binding in a number of enzymes.


Pssm-ID: 396193 [Multi-domain]  Cd Length: 348  Bit Score: 56.18  E-value: 1.21e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928476047   15 TDVLVVGAGPAGSATAAWAARHGLDVVL----ADSATFPRdkacGDGLTPRAIAELGHLGLGAWVDSHGTnrglRAHGFG 90
Cdd:pfam01494   2 TDVLIVGGGPAGLMLALLLARAGVRVVLverhATTSVLPR----AHGLNQRTMELLRQAGLEDRILAEGV----PHEGMG 73

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928476047   91 QVLELPWPGGSLPAHGS-----AIPRTELDAGIRRVALEAGATPMEDAKAVDVTFSGGRVDSVVFD--DG--RSVRCRRL 161
Cdd:pfam01494  74 LAFYNTRRRADLDFLTSpprvtVYPQTELEPILVEHAEARGAQVRFGTEVLSLEQDGDGVTAVVRDrrDGeeYTVRAKYL 153

                         170       180
                  ....*....|....*....|....*....
gi 928476047  162 VVADGARSTLGRVLG--REWHQDTAYGVA 188
Cdd:pfam01494 154 VGCDGGRSPVRKTLGieFEGFEGVPFGSL 182
PRK06184 PRK06184
hypothetical protein; Provisional
 12-176 4.21e-07

hypothetical protein; Provisional


Pssm-ID: 235728 [Multi-domain]  Cd Length: 502  Bit Score: 51.91  E-value: 4.21e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928476047  12 PDSTDVLVVGAGPAGSATAAWAARHGLDVVLADSATFPRDKACGDGLTPRAIAELGHLGLGAWVDSHGTN--RGLRAHGF 89
Cdd:PRK06184   1 YTTTDVLIVGAGPTGLTLAIELARRGVSFRLIEKAPEPFPGSRGKGIQPRTQEVFDDLGVLDRVVAAGGLypPMRIYRDD 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928476047  90 GQVLELPWPGGSLPAHGSA------IPRTELDAGIRRVALEAGATPMEDAKAVDVTFSGGRVDSVVF--DDGRSVRCRRL 161
Cdd:PRK06184  81 GSVAESDMFAHLEPTPDEPyplplmVPQWRTERILRERLAELGHRVEFGCELVGFEQDADGVTARVAgpAGEETVRARYL 160

                        170
                 ....*....|....*
gi 928476047 162 VVADGARSTLGRVLG 176
Cdd:PRK06184 161 VGADGGRSFVRKALG 175
 
Name Accession Description Interval E-value
GG-red-SF TIGR02032
geranylgeranyl reductase family; This model represents a subfamily which includes ...
 16-322 8.91e-63

geranylgeranyl reductase family; This model represents a subfamily which includes geranylgeranyl reductases involved in chlorophyll and bacteriochlorophyll biosynthesis as well as other related enzymes which may also act on geranylgeranyl groups or related substrates. [Biosynthesis of cofactors, prosthetic groups, and carriers, Chlorophyll and bacteriochlorphyll]


Pssm-ID: 273936 [Multi-domain]  Cd Length: 295  Bit Score: 204.48  E-value: 8.91e-63
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928476047   16 DVLVVGAGPAGSATAAWAARHGLDVVLADSATFPRDKACGDGLTPRAIAELGHLGLGAWVDshgTNRGLRAHGFGQVLEL 95
Cdd:TIGR02032   2 DVVVVGAGPAGASAAYRLADKGLRVLLLEKKSFPRYKPCGGALSPRALEELDLPGELIVNL---VRGARFFSPNGDSVEI 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928476047   96 PWPGGSlpahGSAIPRTELDAGIRRVALEAGATPMEDAKAVDVTFSGGRVDSVVFDDGRSVRCRRLVVADGARSTLGRVL 175
Cdd:TIGR02032  79 PIETEL----AYVIDRDAFDEQLAERAQEAGAELRLGTRVLDVEIHDDRVVVIVRGSEGTVTAKIVIGADGSRSIVAKKL 154

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928476047  176 GrEWHQDTAYGVAARGYVTSgrHADPWISSHLELRGEADEVLAGYGWLFPLNDGRVNIGVGTLATdrrPANIKLRGLIDH 255
Cdd:TIGR02032 155 G-LKKEPREYGVAARAEVEM--PDEEVDEDFVEVYIDRGIVPGGYGWVFPKGDGTANVGVGSRSA---EEGEDPKKYLKD 228

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 928476047  256 YAnARRAEWELGPKVElVRSALLPMGGAVSGVAGPNWALVGDAAGCVNPLNGEGIDYGLETGRLVAE 322
Cdd:TIGR02032 229 FL-ARRPELKDAETVE-VCGALIPIGRPDEKLVRGNVLLVGDAAGHVNPLTGEGIYYAMRSGDIAAE 293
FixC COG0644
Dehydrogenase (flavoprotein) [Energy production and conversion];
35-339 2.73e-49

Dehydrogenase (flavoprotein) [Energy production and conversion];


Pssm-ID: 440409 [Multi-domain]  Cd Length: 281  Bit Score: 168.99  E-value: 2.73e-49
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928476047  35 RHGLDVVLADSATFPRDKACGDGLTPRAIAELGHLGLGAWVDSHGTNRGLRAHGfGQVLELPWPGGslpaHGSAIPRTEL 114
Cdd:COG0644   14 RAGLSVLLLEKGSFPGDKICGGGLLPRALEELEPLGLDEPLERPVRGARFYSPG-GKSVELPPGRG----GGYVVDRARF 88

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928476047 115 DAGIRRVALEAGATPMEDAKAVDVTFSGGRVdSVVFDDGRSVRCRRLVVADGARSTLGRVLG----REWHQDTAYGVAAR 190
Cdd:COG0644   89 DRWLAEQAEEAGAEVRTGTRVTDVLRDDGRV-VVRTGDGEEIRADYVVDADGARSLLARKLGlkrrSDEPQDYALAIKEH 167

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928476047 191 GYVTSGRHADPWISSHLELRGEADevlaGYGWLFPLNDGRVNIGVgtlatdrrpaniklrglidhyanarraewelgpkv 270
Cdd:COG0644  168 WELPPLEGVDPGAVEFFFGEGAPG----GYGWVFPLGDGRVSVGI----------------------------------- 208

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 928476047 271 elvrsallPMGGAVSGVAGPNWALVGDAAGCVNPLNGEGIDYGLETGRLVAELLASGADLDRAWPATLR 339
Cdd:COG0644  209 --------PLGGPRPRLVGDGVLLVGDAAGFVDPLTGEGIHLAMKSGRLAAEAIAEALEGGDFSAEALA 269
UbiH COG0654
2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases [Coenzyme ...
 12-340 2.56e-15

2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases [Coenzyme transport and metabolism, Energy production and conversion]; 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases is part of the Pathway/BioSystem: Ubiquinone biosynthesis


Pssm-ID: 440419 [Multi-domain]  Cd Length: 326  Bit Score: 76.52  E-value: 2.56e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928476047  12 PDSTDVLVVGAGPAGSATAAWAARHGLDVVLADSATFPRDKACGDGLTPRAIAELGHLGLGAWVDSHGT---NRGLRAHG 88
Cdd:COG0654    1 MMRTDVLIVGGGPAGLALALALARAGIRVTVVERAPPPRPDGRGIALSPRSLELLRRLGLWDRLLARGApirGIRVRDGS 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928476047  89 FGQVLELPWPGGSLPAHGSAIPRTELDAGIRRVALEAGATPMEDAKAVDVTFSGGRVdSVVFDDGRSVRCRRLVVADGAR 168
Cdd:COG0654   81 DGRVLARFDAAETGLPAGLVVPRADLERALLEAARALGVELRFGTEVTGLEQDADGV-TVTLADGRTLRADLVVGADGAR 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928476047 169 STLgrvlgREWhqdtaYGVAARGYVTSGRHAdpWISSHLELRGEADEVLAGYGWLFPLNDgrvnigVGTLATDRRPAnik 248
Cdd:COG0654  160 SAV-----RRL-----LGIGFTGRDYPQRAL--WAGVRTELRARLAAAGPRLGELLELSP------RSAFPLRRRRA--- 218

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928476047 249 lrgliDHYanarraewelgpkvelvrsallpmggavsgvAGPNWALVGDAAGCVNPLNGEGIDYGLETGRLVAELLASgA 328
Cdd:COG0654  219 -----ERW-------------------------------RRGRVVLLGDAAHTMHPLGGQGANLALRDAAALAWKLAA-A 261

                        330
                 ....*....|..
gi 928476047 329 DLDRAWPATLRS 340
Cdd:COG0654  262 LRGRDDEAALAR 273
FAD_binding_3 pfam01494
FAD binding domain; This domain is involved in FAD binding in a number of enzymes.
 15-188 1.21e-08

FAD binding domain; This domain is involved in FAD binding in a number of enzymes.


Pssm-ID: 396193 [Multi-domain]  Cd Length: 348  Bit Score: 56.18  E-value: 1.21e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928476047   15 TDVLVVGAGPAGSATAAWAARHGLDVVL----ADSATFPRdkacGDGLTPRAIAELGHLGLGAWVDSHGTnrglRAHGFG 90
Cdd:pfam01494   2 TDVLIVGGGPAGLMLALLLARAGVRVVLverhATTSVLPR----AHGLNQRTMELLRQAGLEDRILAEGV----PHEGMG 73

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928476047   91 QVLELPWPGGSLPAHGS-----AIPRTELDAGIRRVALEAGATPMEDAKAVDVTFSGGRVDSVVFD--DG--RSVRCRRL 161
Cdd:pfam01494  74 LAFYNTRRRADLDFLTSpprvtVYPQTELEPILVEHAEARGAQVRFGTEVLSLEQDGDGVTAVVRDrrDGeeYTVRAKYL 153

                         170       180
                  ....*....|....*....|....*....
gi 928476047  162 VVADGARSTLGRVLG--REWHQDTAYGVA 188
Cdd:pfam01494 154 VGCDGGRSPVRKTLGieFEGFEGVPFGSL 182
PRK06184 PRK06184
hypothetical protein; Provisional
 12-176 4.21e-07

hypothetical protein; Provisional


Pssm-ID: 235728 [Multi-domain]  Cd Length: 502  Bit Score: 51.91  E-value: 4.21e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928476047  12 PDSTDVLVVGAGPAGSATAAWAARHGLDVVLADSATFPRDKACGDGLTPRAIAELGHLGLGAWVDSHGTN--RGLRAHGF 89
Cdd:PRK06184   1 YTTTDVLIVGAGPTGLTLAIELARRGVSFRLIEKAPEPFPGSRGKGIQPRTQEVFDDLGVLDRVVAAGGLypPMRIYRDD 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928476047  90 GQVLELPWPGGSLPAHGSA------IPRTELDAGIRRVALEAGATPMEDAKAVDVTFSGGRVDSVVF--DDGRSVRCRRL 161
Cdd:PRK06184  81 GSVAESDMFAHLEPTPDEPyplplmVPQWRTERILRERLAELGHRVEFGCELVGFEQDADGVTARVAgpAGEETVRARYL 160

                        170
                 ....*....|....*
gi 928476047 162 VVADGARSTLGRVLG 176
Cdd:PRK06184 161 VGADGGRSFVRKALG 175
PLN00093 PLN00093
geranylgeranyl diphosphate reductase; Provisional
 220-329 5.56e-06

geranylgeranyl diphosphate reductase; Provisional


Pssm-ID: 177713 [Multi-domain]  Cd Length: 450  Bit Score: 48.21  E-value: 5.56e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928476047 220 YGWLFPLNDgRVNIGVGTLATdrRPAniklrglIDHYANARRAEWE---LGPKVELVRSALLPMGGAVSGVAGpNWALVG 296
Cdd:PLN00093 247 YGWVFPKCD-HVAVGTGTVVN--KPA-------IKKYQRATRNRAKdkiAGGKIIRVEAHPIPEHPRPRRVRG-RVALVG 315

                         90       100       110
                 ....*....|....*....|....*....|...
gi 928476047 297 DAAGCVNPLNGEGIDYGLETGRLVAELLASGAD 329
Cdd:PLN00093 316 DAAGYVTKCSGEGIYFAAKSGRMCAEAIVEGSE 348
Ubi-OHases TIGR01988
Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; This model represents a ...
 16-358 7.58e-06

Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; This model represents a family of FAD-dependent hydroxylases (monooxygenases) which are all believed to act in the aerobic ubiquinone biosynthesis pathway. A separate set of hydroxylases, as yet undiscovered, are believed to be active under anaerobic conditions. In E. coli three enzyme activities have been described, UbiB (which acts first at position 6, see TIGR01982), UbiH (which acts at position 4) and UbiF (which acts at position 5). UbiH and UbiF are similar to one another and form the basis of this subfamily. Interestingly, E. coli contains another hydroxylase gene, called visC, that is highly similar to UbiF, adjacent to UbiH and, when mutated, results in a phenotype similar to that of UbiH (which has also been named visB). Several other species appear to have three homologs in this family, although they assort themselves differently on phylogenetic trees (e.g. Xylella and Mesorhizobium) making it difficult to ascribe a specific activity to each one. Eukaryotes appear to have only a single homolog in this subfamily (COQ6) which complements UbiH, but also possess a non-orthologous gene, COQ7 which complements UbiF. [Biosynthesis of cofactors, prosthetic groups, and carriers, Menaquinone and ubiquinone]


Pssm-ID: 273913 [Multi-domain]  Cd Length: 385  Bit Score: 47.97  E-value: 7.58e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928476047   16 DVLVVGAGPAGSATAAWAARHGLDVVLADSATFPRDKACG-DG----LTPRAIAELGHLGLGAWVDSHGTN--RGLR--- 85
Cdd:TIGR01988   1 DIVIVGGGMVGLALALALARSGLKVALIEATPLPAPADPGfDNrvsaLSAASIRLLEKLGVWDKIEPARAQpiRDIHvsd 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928476047   86 AHGFGQVlELPWPGGSLPAHGSAIPRTEL-DAGIRRVALEAGATPMEDAKAVDVTFSGGRVdSVVFDDGRSVRCRRLVVA 164
Cdd:TIGR01988  81 GGSFGAL-RFDADEIGLEALGYVVENRVLqQALWERLQELPNVTLLCPARVVELPRHSDHV-ELTLDDGQQLRARLLVGA 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928476047  165 DGARSTLGRVLGREWHQdTAYGvaARGYVTSGRHADPwisshleLRGEADEV------LAgygwLFPLNDGRVNIgVGTL 238
Cdd:TIGR01988 159 DGANSKVRQLAGIPTTG-WDYG--QSAVVANVKHERP-------HQGTAWERftptgpLA----LLPLPDNRSSL-VWTL 223

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928476047  239 ATDRrpANiKLRGLID---HYANARRAEWELGPKVELVRSALLPMGGA-VSGVAGPNWALVGDAAGCVNPLNGEGIDYGL 314
Cdd:TIGR01988 224 PPEE--AE-RLLALSDeefLAELQRAFGSRLGAITLVGERHAFPLSLThAKRYVAPRLALIGDAAHTIHPLAGQGLNLGL 300

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|....*...
gi 928476047  315 ----ETGRLVAELLASGADLdrAWPATLRshyglAFSIARRLAGLITI 358
Cdd:TIGR01988 301 rdvaALAEVLEDARRRGEDI--GSLRVLQ-----RYERRRRFDNAAML 341
carotene-cycl TIGR01790
lycopene cyclase family protein; This family includes lycopene beta and epsilion cyclases ...
 16-333 3.42e-05

lycopene cyclase family protein; This family includes lycopene beta and epsilion cyclases (which form beta and delta carotene, respectively) from bacteria and plants as well as the plant capsanthin/capsorubin and neoxanthin cyclases which appear to have evolved from the plant lycopene cyclases. The plant lycopene epsilon cyclases also transform neurosporene to alpha zeacarotene.


Pssm-ID: 130850 [Multi-domain]  Cd Length: 388  Bit Score: 45.89  E-value: 3.42e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928476047   16 DVLVVGAGPAGSATAAWAARHGLDVVLADsatfPRDKACGDGLTPRAIAELGHLGLGAWVDSHGTNrGLRAHGFGQVLEL 95
Cdd:TIGR01790   1 DLAVIGGGPAGLAIALELARPGLRVQLIE----PHPPIPGNHTYGVWDDDLSDLGLADCVEHVWPD-VYEYRFPKQPRKL 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928476047   96 PWPGGSLpahgsaiPRTELDAGIRRVALEAGATpMEDAKAVDVTFSGGRVDSVVFDDGRSVRCRRLVVADGARSTLGRVL 175
Cdd:TIGR01790  76 GTAYGSV-------DSTRLHEELLQKCPEGGVL-WLERKAIHAEADGVALSTVYCAGGQRIQARLVIDARGFGPLVQYVR 147

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928476047  176 G--REWHQdTAYGVAARgyvTSGRHADP-------WISSHLElRGEADEVLAGYGWLFPLNDGRVNIGVGTLATDRRPAN 246
Cdd:TIGR01790 148 FplNVGFQ-VAYGVEAR---LSRPPHGPssmvimdARVDQLA-APELKGYRPTFLYAMPLGSTRVFIEETSLADRPALPR 222

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928476047  247 IKLRGLIDHYANARraEWELGpkvELVRS--ALLPMGGAVSgVAGPNWALVGDAAGCVNPLNGEGIDYGLETGRLVAELL 324
Cdd:TIGR01790 223 DRLRQRILARLNAQ--GWQIK---TIEEEewGALPVGLPGP-FLPQRVAAFGAAAGMVHPTTGYSVARALSDAPGLAAAI 296


                  ....*....
gi 928476047  325 ASGADLDRA 333
Cdd:TIGR01790 297 AQALCQSSE 305
COQ6 TIGR01989
ubiquinone biosynthesis monooxygenase COQ6; This model represents the monooxygenase ...
 248-328 3.21e-04

ubiquinone biosynthesis monooxygenase COQ6; This model represents the monooxygenase responsible for the 4-hydroxylateion of the phenol ring in the aerobic biosynthesis of ubiquinone


Pssm-ID: 273914 [Multi-domain]  Cd Length: 437  Bit Score: 42.82  E-value: 3.21e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928476047  248 KLRGLIDHYANARRAEWELGPKVELV---RSALLPMG-GAVSGVAGPNWALVGDAAGCVNPLNGEGIDYGLETGRLVAEL 323
Cdd:TIGR01989 287 KLNEDIGFRTEGSKSCFQVPPRVIGVvdkSRAAFPLGlGHADEYVTKRVALVGDAAHRVHPLAGQGVNLGFGDVASLVKA 366


                  ....*
gi 928476047  324 LASGA 328
Cdd:TIGR01989 367 LAEAV 371
PRK07333 PRK07333
ubiquinone biosynthesis hydroxylase;
109-332 3.68e-04

ubiquinone biosynthesis hydroxylase;


Pssm-ID: 180935 [Multi-domain]  Cd Length: 403  Bit Score: 42.66  E-value: 3.68e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928476047 109 IPRTELDAGIRRVALEAGATPMEDAKAVDVTFSGGRVdSVVFDDGRSVRCRRLVVADGARSTLGRVLG---REWhqdtAY 185
Cdd:PRK07333 108 VENRVLINALRKRAEALGIDLREATSVTDFETRDEGV-TVTLSDGSVLEARLLVAADGARSKLRELAGiktVGW----DY 182

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928476047 186 GVAarGYVTSGRHADPwissHlelRGEADE--VLAGYGWLFPLNDGRVNIgVGTLATDRRPANIKLRGLIDHYANARRAE 263
Cdd:PRK07333 183 GQS--GIVCTVEHERP----H---GGRAEEhfLPAGPFAILPLKGNRSSL-VWTERTADAERLVALDDLVFEAELEQRFG 252

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 928476047 264 WELGP-KVELVRSAlLPMGGAVS-GVAGPNWALVGDAAGCVNPLNGEGIDYGLetgRLVAELLASGADLDR 332
Cdd:PRK07333 253 HRLGElKVLGKRRA-FPLGLTLArSFVAPRFALVGDAAHGIHPIAGQGLNLGL---KDVAALAEVVVEAAR 319
PRK07608 PRK07608
UbiH/UbiF family hydroxylase;
113-326 1.11e-03

UbiH/UbiF family hydroxylase;


Pssm-ID: 181057 [Multi-domain]  Cd Length: 388  Bit Score: 41.09  E-value: 1.11e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928476047 113 ELDAGIRRvaleAGATPMEDAKAVDVTFSGGRVdSVVFDDGRSVRCRRLVVADGARSTLgrvlgrewHQDTAYGVAARGY 192
Cdd:PRK07608 116 ALWAALRF----QPNLTWFPARAQGLEVDPDAA-TLTLADGQVLRADLVVGADGAHSWV--------RSQAGIKAERRPY 182

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928476047 193 VTSGRHADpwISSHLELRGEA------DEVLAgygwLFPLNDGRVNIgVGTLATDRRPANIKLRGLIDHYANARRAEWEL 266
Cdd:PRK07608 183 RQTGVVAN--FKAERPHRGTAyqwfrdDGILA----LLPLPDGHVSM-VWSARTAHADELLALSPEALAARVERASGGRL 255

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 928476047 267 GpKVELVRSAL---LPMGGAVSGVAgPNWALVGDAAGCVNPLNGEGIDYGLETGRLVAELLAS 326
Cdd:PRK07608 256 G-RLECVTPAAgfpLRLQRVDRLVA-PRVALVGDAAHLIHPLAGQGMNLGLRDVAALADVLAG 316
PRK11445 PRK11445
FAD-binding protein;
291-337 2.51e-03

FAD-binding protein;


Pssm-ID: 183139 [Multi-domain]  Cd Length: 351  Bit Score: 39.66  E-value: 2.51e-03
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*....
gi 928476047 291 NWALVGDAAGCVNPLNGEGIDYGLETGRLVAELLASGADL--DRAWPAT 337
Cdd:PRK11445 265 NAFLIGEAAGFISPSSLEGISYALDSARILSEVLNKQPEKlnTAYWRKT 313
mhpA PRK06183
bifunctional 3-(3-hydroxy-phenyl)propionate/3-hydroxycinnamic acid hydroxylase;
7-180 3.09e-03

bifunctional 3-(3-hydroxy-phenyl)propionate/3-hydroxycinnamic acid hydroxylase;


Pssm-ID: 235727 [Multi-domain]  Cd Length: 500  Bit Score: 39.89  E-value: 3.09e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928476047   7 PPATTPDSTDVLVVGAGPAGSATAAWAARHGLDVVLAD--SATFPRDKACG-DGLTPRAIAElghLGLGAWVDSHGT-NR 82
Cdd:PRK06183   3 AQHPDAHDTDVVIVGAGPVGLTLANLLGQYGVRVLVLErwPTLYDLPRAVGiDDEALRVLQA---IGLADEVLPHTTpNH 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928476047  83 GLRAH-GFGQVL-ELPWPGGSlpAHG----SAIPRTELDAGIR-RVALEAGATPMEDAKAVDVTFSGGRVdSVVFDD--- 152
Cdd:PRK06183  80 GMRFLdAKGRCLaEIARPSTG--EFGwprrNAFHQPLLEAVLRaGLARFPHVRVRFGHEVTALTQDDDGV-TVTLTDadg 156

                        170       180
                 ....*....|....*....|....*....
gi 928476047 153 -GRSVRCRRLVVADGARSTLGRVLGREWH 180
Cdd:PRK06183 157 qRETVRARYVVGCDGANSFVRRTLGVPFE 185
PRK05732 PRK05732
2-octaprenyl-6-methoxyphenyl hydroxylase; Validated
 133-198 7.15e-03

2-octaprenyl-6-methoxyphenyl hydroxylase; Validated


Pssm-ID: 235584 [Multi-domain]  Cd Length: 395  Bit Score: 38.30  E-value: 7.15e-03
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 928476047 133 AKAVDVTFSGGRVdSVVFDDGRSVRCRRLVVADGARSTLGRVLGREWHQdTAYG-VAARGYVTSGRH 198
Cdd:PRK05732 134 ARVANVERTQGSV-RVTLDDGETLTGRLLVAADGSHSALREALGIDWQQ-HPYEqVAVIANVTTSEA 198
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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