|
Name |
Accession |
Description |
Interval |
E-value |
| MalK |
COG3839 |
ABC-type sugar transport system, ATPase component MalK [Carbohydrate transport and metabolism]; ... |
1-369 |
0e+00 |
|
ABC-type sugar transport system, ATPase component MalK [Carbohydrate transport and metabolism];
Pssm-ID: 443050 [Multi-domain] Cd Length: 352 Bit Score: 551.60 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 1 MASISLRGVQKAYGdGAPVIRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLSIGGKIMNDVPAAQRGVAM 80
Cdd:COG3839 1 MASLELENVSKSYG-GVEALKDIDLDIEDGEFLVLLGPSGCGKSTLLRMIAGLEDPTSGEILIGGRDVTDLPPKDRNIAM 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 81 VFQSYALFPHMTVFENMAFGLKLAKTPKEEIDRKVREAARVLQLEALLERRPKALSGGQRQRVAIGRAIVRQPGVFLFDE 160
Cdd:COG3839 80 VFQSYALYPHMTVYENIAFPLKLRKVPKAEIDRRVREAAELLGLEDLLDRKPKQLSGGQRQRVALGRALVREPKVFLLDE 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 161 PLSNLDATLRGQTRIEIARLHKQFaKASVVYVTHDQIEAMTLADKIVLLHAGKdterygsIAQIGAPLELYHRPKSRFVA 240
Cdd:COG3839 160 PLSNLDAKLRVEMRAEIKRLHRRL-GTTTIYVTHDQVEAMTLADRIAVMNDGR-------IQQVGTPEELYDRPANLFVA 231
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 241 GFIGSPRMNFLPGRVASVDAQgvivtldttLENVRVPV-DGAALEVAQPVTLGVRPEHLEFIDTsslqDEAVLTRTVSLV 319
Cdd:COG3839 232 GFIGSPPMNLLPGTVEGGGVR---------LGGVRLPLpAALAAAAGGEVTLGIRPEHLRLADE----GDGGLEATVEVV 298
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|
gi 928002514 320 EQLGEHSYVHLDqPGGFTLIAKAPGDTHLAPGDRAHLRVPRHATHLFTED 369
Cdd:COG3839 299 EPLGSETLVHVR-LGGQELVARVPGDTRLRPGDTVRLAFDPERLHLFDAE 347
|
|
| PRK11000 |
PRK11000 |
maltose/maltodextrin ABC transporter ATP-binding protein MalK; |
1-372 |
0e+00 |
|
maltose/maltodextrin ABC transporter ATP-binding protein MalK;
Pssm-ID: 182893 [Multi-domain] Cd Length: 369 Bit Score: 523.44 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 1 MASISLRGVQKAYGDgAPVIRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLSIGGKIMNDVPAAQRGVAM 80
Cdd:PRK11000 1 MASVTLRNVTKAYGD-VVISKDINLDIHEGEFVVFVGPSGCGKSTLLRMIAGLEDITSGDLFIGEKRMNDVPPAERGVGM 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 81 VFQSYALFPHMTVFENMAFGLKLAKTPKEEIDRKVREAARVLQLEALLERRPKALSGGQRQRVAIGRAIVRQPGVFLFDE 160
Cdd:PRK11000 80 VFQSYALYPHLSVAENMSFGLKLAGAKKEEINQRVNQVAEVLQLAHLLDRKPKALSGGQRQRVAIGRTLVAEPSVFLLDE 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 161 PLSNLDATLRGQTRIEIARLHKQFaKASVVYVTHDQIEAMTLADKIVLLHAGKdterygsIAQIGAPLELYHRPKSRFVA 240
Cdd:PRK11000 160 PLSNLDAALRVQMRIEISRLHKRL-GRTMIYVTHDQVEAMTLADKIVVLDAGR-------VAQVGKPLELYHYPANRFVA 231
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 241 GFIGSPRMNFLPGRVASVDAQGVIVTLDTTLeNVRVPVDGAALEVAQPVTLGVRPEHLefidTSSLQDEAVLTRTVSLVE 320
Cdd:PRK11000 232 GFIGSPKMNFLPVKVTATAIEQVQVELPNRQ-QVWLPVEGRGVQVGANMSLGIRPEHL----LPSDIADVTLEGEVQVVE 306
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|...
gi 928002514 321 QLGEHSYVHLDQPGG-FTLIAKAPGDTHLAPGDRAHLRVPRHATHLFTEDGFA 372
Cdd:PRK11000 307 QLGNETQIHIQIPAIrQNLVYRQNDVVLVEEGATFAIGLPPERCHLFREDGTA 359
|
|
| ugpC |
PRK11650 |
sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC; |
1-370 |
9.72e-175 |
|
sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC;
Pssm-ID: 236947 [Multi-domain] Cd Length: 356 Bit Score: 490.51 E-value: 9.72e-175
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 1 MASISLRGVQKAYGDGAPVIRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLSIGGKIMNDVPAAQRGVAM 80
Cdd:PRK11650 1 MAGLKLQAVRKSYDGKTQVIKGIDLDVADGEFIVLVGPSGCGKSTLLRMVAGLERITSGEIWIGGRVVNELEPADRDIAM 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 81 VFQSYALFPHMTVFENMAFGLKLAKTPKEEIDRKVREAARVLQLEALLERRPKALSGGQRQRVAIGRAIVRQPGVFLFDE 160
Cdd:PRK11650 81 VFQNYALYPHMSVRENMAYGLKIRGMPKAEIEERVAEAARILELEPLLDRKPRELSGGQRQRVAMGRAIVREPAVFLFDE 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 161 PLSNLDATLRGQTRIEIARLHKQFAKASvVYVTHDQIEAMTLADKIVLLHAGKdterygsIAQIGAPLELYHRPKSRFVA 240
Cdd:PRK11650 161 PLSNLDAKLRVQMRLEIQRLHRRLKTTS-LYVTHDQVEAMTLADRVVVMNGGV-------AEQIGTPVEVYEKPASTFVA 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 241 GFIGSPRMNFLPGRvasVDAQGVIVTLDTtleNVRVPVDGAALEVA-QPVTLGVRPEHLEfidtsSLQDEAVLTRTVSLV 319
Cdd:PRK11650 233 SFIGSPAMNLLDGR---VSADGAAFELAG---GIALPLGGGYRQYAgRKLTLGIRPEHIA-----LSSAEGGVPLTVDTV 301
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|.
gi 928002514 320 EQLGEHSYVHLDQPGGfTLIAKAPGDTHLAPGDRAHLRVPRHATHLFTEDG 370
Cdd:PRK11650 302 ELLGADNLAHGRWGGQ-PLVVRLPHQERPAAGSTLWLHLPANQLHLFDADT 351
|
|
| PotA |
COG3842 |
ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component [Amino acid transport ... |
1-368 |
1.06e-153 |
|
ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 443052 [Multi-domain] Cd Length: 353 Bit Score: 437.22 E-value: 1.06e-153
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 1 MASISLRGVQKAYGDgAPVIRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLSIGGKIMNDVPAAQRGVAM 80
Cdd:COG3842 3 MPALELENVSKRYGD-VTALDDVSLSIEPGEFVALLGPSGCGKTTLLRMIAGFETPDSGRILLDGRDVTGLPPEKRNVGM 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 81 VFQSYALFPHMTVFENMAFGLKLAKTPKEEIDRKVREAARVLQLEALLERRPKALSGGQRQRVAIGRAIVRQPGVFLFDE 160
Cdd:COG3842 82 VFQDYALFPHLTVAENVAFGLRMRGVPKAEIRARVAELLELVGLEGLADRYPHQLSGGQQQRVALARALAPEPRVLLLDE 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 161 PLSNLDATLRGQTRIEIARLHKQFaKASVVYVTHDQIEAMTLADKIVLLHAGKdterygsIAQIGAPLELYHRPKSRFVA 240
Cdd:COG3842 162 PLSALDAKLREEMREELRRLQREL-GITFIYVTHDQEEALALADRIAVMNDGR-------IEQVGTPEEIYERPATRFVA 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 241 GFIGspRMNFLPGRVASVDAQGVivtlDTTLENVRVPVDgAALEVAQPVTLGVRPEHLEFIDTSslqDEAVLTRTVSLVE 320
Cdd:COG3842 234 DFIG--EANLLPGTVLGDEGGGV----RTGGRTLEVPAD-AGLAAGGPVTVAIRPEDIRLSPEG---PENGLPGTVEDVV 303
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|
gi 928002514 321 QLGEHSYVHLDQPGGFTLIAKAPGDT--HLAPGDRAHLRVPRHATHLFTE 368
Cdd:COG3842 304 FLGSHVRYRVRLGDGQELVVRVPNRAalPLEPGDRVGLSWDPEDVVVLPA 353
|
|
| ABC_MalK_N |
cd03301 |
The N-terminal ATPase domain of the maltose transporter, MalK; ATP binding cassette (ABC) ... |
4-225 |
1.34e-118 |
|
The N-terminal ATPase domain of the maltose transporter, MalK; ATP binding cassette (ABC) proteins function from bacteria to human, mediating the translocation of substances into and out of cells or organelles. ABC transporters contain two transmembrane-spanning domains (TMDs) or subunits and two nucleotide binding domains (NBDs) or subunits that couple transport to the hydrolysis of ATP. In the maltose transport system, the periplasmic maltose binding protein (MBP) stimulates the ATPase activity of the membrane-associated transporter, which consists of two transmembrane subunits, MalF and MalG, and two copies of the ATP binding subunit, MalK, and becomes tightly bound to the transporter in the catalytic transition state, ensuring that maltose is passed to the transporter as ATP is hydrolyzed.
Pssm-ID: 213268 [Multi-domain] Cd Length: 213 Bit Score: 342.70 E-value: 1.34e-118
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 4 ISLRGVQKAYGDgAPVIRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLSIGGKIMNDVPAAQRGVAMVFQ 83
Cdd:cd03301 1 VELENVTKRFGN-VTALDDLNLDIADGEFVVLLGPSGCGKTTTLRMIAGLEEPTSGRIYIGGRDVTDLPPKDRDIAMVFQ 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 84 SYALFPHMTVFENMAFGLKLAKTPKEEIDRKVREAARVLQLEALLERRPKALSGGQRQRVAIGRAIVRQPGVFLFDEPLS 163
Cdd:cd03301 80 NYALYPHMTVYDNIAFGLKLRKVPKDEIDERVREVAELLQIEHLLDRKPKQLSGGQRQRVALGRAIVREPKVFLMDEPLS 159
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 928002514 164 NLDATLRGQTRIEIARLHKQFaKASVVYVTHDQIEAMTLADKIVLLHAGKdterygsIAQIG 225
Cdd:cd03301 160 NLDAKLRVQMRAELKRLQQRL-GTTTIYVTHDQVEAMTMADRIAVMNDGQ-------IQQIG 213
|
|
| potA |
PRK09452 |
spermidine/putrescine ABC transporter ATP-binding protein PotA; |
4-298 |
7.08e-111 |
|
spermidine/putrescine ABC transporter ATP-binding protein PotA;
Pssm-ID: 236523 [Multi-domain] Cd Length: 375 Bit Score: 329.22 E-value: 7.08e-111
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 4 ISLRGVQKAYgDGAPVIRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLSIGGKIMNDVPAAQRGVAMVFQ 83
Cdd:PRK09452 15 VELRGISKSF-DGKEVISNLDLTINNGEFLTLLGPSGCGKTTVLRLIAGFETPDSGRIMLDGQDITHVPAENRHVNTVFQ 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 84 SYALFPHMTVFENMAFGLKLAKTPKEEIDRKVREAARVLQLEALLERRPKALSGGQRQRVAIGRAIVRQPGVFLFDEPLS 163
Cdd:PRK09452 94 SYALFPHMTVFENVAFGLRMQKTPAAEITPRVMEALRMVQLEEFAQRKPHQLSGGQQQRVAIARAVVNKPKVLLLDESLS 173
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 164 NLDATLRGQTRIEIARLHKQFAkASVVYVTHDQIEAMTLADKIVLLHAGKdterygsIAQIGAPLELYHRPKSRFVAGFI 243
Cdd:PRK09452 174 ALDYKLRKQMQNELKALQRKLG-ITFVFVTHDQEEALTMSDRIVVMRDGR-------IEQDGTPREIYEEPKNLFVARFI 245
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*.
gi 928002514 244 GSprMNFLPGRV-ASVDAQGVIVTLDTTLENVRVPVDgaaLEVAQPVTLGVRPEHL 298
Cdd:PRK09452 246 GE--INIFDATViERLDEQRVRANVEGRECNIYVNFA---VEPGQKLHVLLRPEDL 296
|
|
| ABC_PotA_N |
cd03300 |
ATP-binding cassette domain of the polyamine transporter; PotA is an ABC-type transporter and ... |
4-244 |
3.90e-108 |
|
ATP-binding cassette domain of the polyamine transporter; PotA is an ABC-type transporter and the ATPase component of the spermidine/putrescine-preferential uptake system consisting of PotA, -B, -C, and -D. PotA has two domains with the N-terminal domain containing the ATPase activity and the residues required for homodimerization with PotA and heterdimerization with PotB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213267 [Multi-domain] Cd Length: 232 Bit Score: 316.87 E-value: 3.90e-108
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 4 ISLRGVQKAYGDGaPVIRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLSIGGKIMNDVPAAQRGVAMVFQ 83
Cdd:cd03300 1 IELENVSKFYGGF-VALDGVSLDIKEGEFFTLLGPSGCGKTTLLRLIAGFETPTSGEILLDGKDITNLPPHKRPVNTVFQ 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 84 SYALFPHMTVFENMAFGLKLAKTPKEEIDRKVREAARVLQLEALLERRPKALSGGQRQRVAIGRAIVRQPGVFLFDEPLS 163
Cdd:cd03300 80 NYALFPHLTVFENIAFGLRLKKLPKAEIKERVAEALDLVQLEGYANRKPSQLSGGQQQRVAIARALVNEPKVLLLDEPLG 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 164 NLDATLRGQTRIEIARLHKQFAkASVVYVTHDQIEAMTLADKIVLLHAGKdterygsIAQIGAPLELYHRPKSRFVAGFI 243
Cdd:cd03300 160 ALDLKLRKDMQLELKRLQKELG-ITFVFVTHDQEEALTMSDRIAVMNKGK-------IQQIGTPEEIYEEPANRFVADFI 231
|
.
gi 928002514 244 G 244
Cdd:cd03300 232 G 232
|
|
| CysA |
COG1118 |
ABC-type sulfate/molybdate transport systems, ATPase component [Inorganic ion transport and ... |
3-365 |
3.57e-105 |
|
ABC-type sulfate/molybdate transport systems, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 440735 [Multi-domain] Cd Length: 348 Bit Score: 313.62 E-value: 3.57e-105
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 3 SISLRGVQKAYGDgAPVIRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLSIGGKIMN-DVPAAQRGVAMV 81
Cdd:COG1118 2 SIEVRNISKRFGS-FTLLDDVSLEIASGELVALLGPSGSGKTTLLRIIAGLETPDSGRIVLNGRDLFtNLPPRERRVGFV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 82 FQSYALFPHMTVFENMAFGLKLAKTPKEEIDRKVREAARVLQLEALLERRPKALSGGQRQRVAIGRAIVRQPGVFLFDEP 161
Cdd:COG1118 81 FQHYALFPHMTVAENIAFGLRVRPPSKAEIRARVEELLELVQLEGLADRYPSQLSGGQRQRVALARALAVEPEVLLLDEP 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 162 LSNLDATLRGQTRIEIARLHKQFaKASVVYVTHDQIEAMTLADKIVLLHAGKdterygsIAQIGAPLELYHRPKSRFVAG 241
Cdd:COG1118 161 FGALDAKVRKELRRWLRRLHDEL-GGTTVFVTHDQEEALELADRVVVMNQGR-------IEQVGTPDEVYDRPATPFVAR 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 242 FIGSPrmNFLPGRVASvdaqGVIVTLDTTLENVRVPVDGaalevaqPVTLGVRPEHLEFIDTSslQDEAVLTRTVSLVEQ 321
Cdd:COG1118 233 FLGCV--NVLRGRVIG----GQLEADGLTLPVAEPLPDG-------PAVAGVRPHDIEVSREP--EGENTFPATVARVSE 297
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|
gi 928002514 322 LGEHS--YVHLDQPGGFTLIAKAPGDT----HLAPGDRAHLRVPRHATHL 365
Cdd:COG1118 298 LGPEVrvELKLEDGEGQPLEAEVTKEAwaelGLAPGDPVYLRPRPARVFL 347
|
|
| ABC_Carb_Solutes_like |
cd03259 |
ATP-binding cassette domain of the carbohydrate and solute transporters-like; This family is ... |
4-225 |
1.60e-100 |
|
ATP-binding cassette domain of the carbohydrate and solute transporters-like; This family is comprised of proteins involved in the transport of apparently unrelated solutes and proteins specific for di- and oligosaccharides and polyols. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213226 [Multi-domain] Cd Length: 213 Bit Score: 296.74 E-value: 1.60e-100
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 4 ISLRGVQKAYGdGAPVIRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLSIGGKIMNDVPAAQRGVAMVFQ 83
Cdd:cd03259 1 LELKGLSKTYG-SVRALDDLSLTVEPGEFLALLGPSGCGKTTLLRLIAGLERPDSGEILIDGRDVTGVPPERRNIGMVFQ 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 84 SYALFPHMTVFENMAFGLKLAKTPKEEIDRKVREAARVLQLEALLERRPKALSGGQRQRVAIGRAIVRQPGVFLFDEPLS 163
Cdd:cd03259 80 DYALFPHLTVAENIAFGLKLRGVPKAEIRARVRELLELVGLEGLLNRYPHELSGGQQQRVALARALAREPSLLLLDEPLS 159
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 928002514 164 NLDATLRGQTRIEIARLHKQFaKASVVYVTHDQIEAMTLADKIVLLHAGKdterygsIAQIG 225
Cdd:cd03259 160 ALDAKLREELREELKELQREL-GITTIYVTHDQEEALALADRIAVMNEGR-------IVQVG 213
|
|
| ABC_arch_GlcV |
NF040933 |
glucose ABC transporter ATP-binding protein GlcV; |
2-366 |
5.53e-92 |
|
glucose ABC transporter ATP-binding protein GlcV;
Pssm-ID: 468866 [Multi-domain] Cd Length: 357 Bit Score: 280.35 E-value: 5.53e-92
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 2 ASISLRGVQKAYGDGAPVI---RDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLSIGGKIMND-----VPA 73
Cdd:NF040933 1 VTVRVENVTKIFKKGKKEVvalDNVNLEIKSGEFFGILGPSGHGKTTFLRIIAGLEVPTDGEIYFDDKLVASpgkiiVPP 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 74 AQRGVAMVFQSYALFPHMTVFENMAFGLKLAKTPKEEIDRKVREAARVLQLEALLERRPKALSGGQRQRVAIGRAIVRQP 153
Cdd:NF040933 81 EDRNIGMVFQNWALYPNMTVFDNIAFPLKIKKVPKDEIEKKVKEVAEILGISEVLDRYPRELSGGQQQRVALARALVKNP 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 154 GVFLFDEPLSNLDATLRGQTRIEIARLHKQFaKASVVYVTHDQIEAMTLADKI-VLLHagkdteryGSIAQIGAPLELYH 232
Cdd:NF040933 161 QVLLLDEPFSNLDARIRDSARALVKKIQREL-KITTIIVSHDPADIFSLADRAgVINN--------GKFQQVGKPEEIYD 231
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 233 RPKSRFVAGFIGSprMNFLPGRVasvdAQGVIVTLDttleNVRVPVDGAALEvAQPVTLGVRPEHLEFIDTSSLQDE--- 309
Cdd:NF040933 232 NPANIFVARLIGD--INLLEGKV----EEEGLVDGN----DLKIPLPNPKLE-AGEVIIGIRPEDIDISESDMRLPPgfv 300
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*..
gi 928002514 310 AVLTRTVSLVEQLGEHSYVHLDQPGGFTLIAKAPGDTHLAPGDRAHLRVPRHATHLF 366
Cdd:NF040933 301 EVGKGRVKVSSYAGGVFRVVVSPIDDDSIEIIVNSDRPIEEGEEVNLYVRPDKIKIF 357
|
|
| PhnT2 |
TIGR03265 |
putative 2-aminoethylphosphonate ABC transporter, ATP-binding protein; This ABC transporter ... |
1-366 |
7.56e-92 |
|
putative 2-aminoethylphosphonate ABC transporter, ATP-binding protein; This ABC transporter ATP-binding protein is found in a number of genomes in operon-like contexts strongly suggesting a substrate specificity for 2-aminoethylphosphonate (2-AEP). The characterized PhnSTUV system is absent in the genomes in which this system is found. These genomes encode systems for the catabolism of 2-AEP, making the need for a 2-AEP-specific transporter likely. [Transport and binding proteins, Amino acids, peptides and amines]
Pssm-ID: 274496 [Multi-domain] Cd Length: 353 Bit Score: 279.61 E-value: 7.56e-92
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 1 MASISLRGVQKAYGDGApVIRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLSIGGKIMNDVPAAQRGVAM 80
Cdd:TIGR03265 2 SPYLSIDNIRKRFGAFT-ALKDISLSVKKGEFVCLLGPSGCGKTTLLRIIAGLERQTAGTIYQGGRDITRLPPQKRDYGI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 81 VFQSYALFPHMTVFENMAFGLKLAKTPKEEIDRKVREAARVLQLEALLERRPKALSGGQRQRVAIGRAIVRQPGVFLFDE 160
Cdd:TIGR03265 81 VFQSYALFPNLTVADNIAYGLKNRGMGRAEVAERVAELLDLVGLPGSERKYPGQLSGGQQQRVALARALATSPGLLLLDE 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 161 PLSNLDATLRGQTRIEIARLHKQFaKASVVYVTHDQIEAMTLADKIVLLHAGKdterygsIAQIGAPLELYHRPKSRFVA 240
Cdd:TIGR03265 161 PLSALDARVREHLRTEIRQLQRRL-GVTTIMVTHDQEEALSMADRIVVMNHGV-------IEQVGTPQEIYRHPATPFVA 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 241 GFIGspRMNFLPGRVASvDAQGVIVTldttlenVRVPVDGAALEVAQPVTLGVRPEHLEFidtSSLQDEA-VLTRTVSLV 319
Cdd:TIGR03265 233 DFVG--EVNWLPGTRGG-GSRARVGG-------LTLACAPGLAQPGASVRLAVRPEDIRV---SPAGNAAnLLLARVEDM 299
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|...
gi 928002514 320 EQLGEHSYVHLDQPG--GFTLIAKAPGD----THLAPGDRAHLRVPRHATHLF 366
Cdd:TIGR03265 300 EFLGAFYRLRLRLEGlpGQALVADVSASeverLGIRAGQPIWIELPAERLRAF 352
|
|
| potA |
TIGR01187 |
spermidine/putrescine ABC transporter ATP-binding subunit; This model describes spermidine ... |
36-357 |
5.28e-88 |
|
spermidine/putrescine ABC transporter ATP-binding subunit; This model describes spermidine/putrescine ABC transporter, ATP binding subunit in bacteria and its equivalents in archaea. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporter is the obligatory coupling of ATP hydrolysis to substrate translocation. The minimal configuration of bacterial ABC transport system: an ATPase or ATP binding subunit; An integral membrane protein; a hydrophilic polypetpide, which likely functions as substrate binding protein. Polyamines like spermidine and putrescine play vital role in cell proliferation, differentiation, and ion homeostasis. The concentration of polyamines within the cell are regulated by biosynthesis, degradation and transport (uptake and efflux included). [Transport and binding proteins, Amino acids, peptides and amines]
Pssm-ID: 162242 [Multi-domain] Cd Length: 325 Bit Score: 268.98 E-value: 5.28e-88
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 36 LGPSGCGKSTLLCMIAGLEDLTDGDLSIGGKIMNDVPAAQRGVAMVFQSYALFPHMTVFENMAFGLKLAKTPKEEIDRKV 115
Cdd:TIGR01187 2 LGPSGCGKTTLLRLLAGFEQPDSGSIMLDGEDVTNVPPHLRHINMVFQSYALFPHMTVEENVAFGLKMRKVPRAEIKPRV 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 116 REAARVLQLEALLERRPKALSGGQRQRVAIGRAIVRQPGVFLFDEPLSNLDATLRGQTRIEIARLHKQFAkASVVYVTHD 195
Cdd:TIGR01187 82 LEALRLVQLEEFADRKPHQLSGGQQQRVALARALVFKPKILLLDEPLSALDKKLRDQMQLELKTIQEQLG-ITFVFVTHD 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 196 QIEAMTLADKIVLLHAGKdterygsIAQIGAPLELYHRPKSRFVAGFIGSPRMNflpgRVASVDAQGVIVTLDTTLENVR 275
Cdd:TIGR01187 161 QEEAMTMSDRIAIMRKGK-------IAQIGTPEEIYEEPANLFVARFIGEINVF----EATVIERKSEQVVLAGVEGRRC 229
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 276 VPVDGAALEVAQPVTLGVRPEHLEFIDTSSLQDEAVLTRTVSLVEQLGEHSYVHLD-QPGGFTLIAKAPGDTHLA----P 350
Cdd:TIGR01187 230 DIYTDVPVEKDQPLHVVLRPEKIVIEEEDEANSSNAIIGHVIDITYLGMTLEVHVRlETGQKVLVSEFFNEDDPHmspsI 309
|
....*..
gi 928002514 351 GDRAHLR 357
Cdd:TIGR01187 310 GDRVGLT 316
|
|
| fbpC |
PRK11432 |
ferric ABC transporter ATP-binding protein; |
6-338 |
1.47e-87 |
|
ferric ABC transporter ATP-binding protein;
Pssm-ID: 183133 [Multi-domain] Cd Length: 351 Bit Score: 268.51 E-value: 1.47e-87
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 6 LRGVQKAYGDgAPVIRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLSIGGKIMNDVPAAQRGVAMVFQSY 85
Cdd:PRK11432 9 LKNITKRFGS-NTVIDNLNLTIKQGTMVTLLGPSGCGKTTVLRLVAGLEKPTEGQIFIDGEDVTHRSIQQRDICMVFQSY 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 86 ALFPHMTVFENMAFGLKLAKTPKEEIDRKVREAARVLQLEALLERRPKALSGGQRQRVAIGRAIVRQPGVFLFDEPLSNL 165
Cdd:PRK11432 88 ALFPHMSLGENVGYGLKMLGVPKEERKQRVKEALELVDLAGFEDRYVDQISGGQQQRVALARALILKPKVLLFDEPLSNL 167
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 166 DATLRGQTRIEIARLHKQFAKASvVYVTHDQIEAMTLADKIVLLHAGKdterygsIAQIGAPLELYHRPKSRFVAGFIGS 245
Cdd:PRK11432 168 DANLRRSMREKIRELQQQFNITS-LYVTHDQSEAFAVSDTVIVMNKGK-------IMQIGSPQELYRQPASRFMASFMGD 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 246 PrmNFLPGRVA--SVDAQGVIVTLDttlenvrvpvDGAALEVAQ-PVTLGVRPE------------------------HL 298
Cdd:PRK11432 240 A--NIFPATLSgdYVDIYGYRLPRP----------AAFAFNLPDgECTVGVRPEaitlseqgeesqrctikhvaymgpQY 307
|
330 340 350 360
....*....|....*....|....*....|....*....|
gi 928002514 299 EFIDTSSLQDEAVLTRTVSLVEQLGEHSYVHLDQPGGFTL 338
Cdd:PRK11432 308 EVTVDWHGQELLLQVNATQLQPDLGEHYYLEIHPYGMFLL 347
|
|
| ABC_CysA_sulfate_importer |
cd03296 |
ATP-binding cassette domain of the sulfate transporter; Part of the ABC transporter complex ... |
3-245 |
4.29e-85 |
|
ATP-binding cassette domain of the sulfate transporter; Part of the ABC transporter complex cysAWTP involved in sulfate import. Responsible for energy coupling to the transport system. The complex is composed of two ATP-binding proteins (cysA), two transmembrane proteins (cysT and cysW), and a solute-binding protein (cysP). ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213263 [Multi-domain] Cd Length: 239 Bit Score: 258.42 E-value: 4.29e-85
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 3 SISLRGVQKAYGDgAPVIRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLSIGGKIMNDVPAAQRGVAMVF 82
Cdd:cd03296 2 SIEVRNVSKRFGD-FVALDDVSLDIPSGELVALLGPSGSGKTTLLRLIAGLERPDSGTILFGGEDATDVPVQERNVGFVF 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 83 QSYALFPHMTVFENMAFGLKLAK----TPKEEIDRKVREAARVLQLEALLERRPKALSGGQRQRVAIGRAIVRQPGVFLF 158
Cdd:cd03296 81 QHYALFRHMTVFDNVAFGLRVKPrserPPEAEIRAKVHELLKLVQLDWLADRYPAQLSGGQRQRVALARALAVEPKVLLL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 159 DEPLSNLDATLRGQTRIEIARLHKQFAKASvVYVTHDQIEAMTLADKIVLLHAGKdterygsIAQIGAPLELYHRPKSRF 238
Cdd:cd03296 161 DEPFGALDAKVRKELRRWLRRLHDELHVTT-VFVTHDQEEALEVADRVVVMNKGR-------IEQVGTPDEVYDHPASPF 232
|
....*..
gi 928002514 239 VAGFIGS 245
Cdd:cd03296 233 VYSFLGE 239
|
|
| TauB |
COG1116 |
ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion ... |
1-224 |
8.86e-79 |
|
ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 440733 [Multi-domain] Cd Length: 260 Bit Score: 243.07 E-value: 8.86e-79
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 1 MASISLRGVQKAYGDGA---PVIRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLSIGGKimnDVPAAQRG 77
Cdd:COG1116 5 APALELRGVSKRFPTGGggvTALDDVSLTVAAGEFVALVGPSGCGKSTLLRLIAGLEKPTSGEVLVDGK---PVTGPGPD 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 78 VAMVFQSYALFPHMTVFENMAFGLKLAKTPKEEIDRKVREAARVLQLEALLERRPKALSGGQRQRVAIGRAIVRQPGVFL 157
Cdd:COG1116 82 RGVVFQEPALLPWLTVLDNVALGLELRGVPKAERRERARELLELVGLAGFEDAYPHQLSGGMRQRVAIARALANDPEVLL 161
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 928002514 158 FDEPLSNLDATLRGQTRIEIARLHKQFaKASVVYVTHDQIEAMTLADKIVLLhagkdTERYGSIAQI 224
Cdd:COG1116 162 MDEPFGALDALTRERLQDELLRLWQET-GKTVLFVTHDVDEAVFLADRVVVL-----SARPGRIVEE 222
|
|
| ABC_ModC_like |
cd03299 |
ATP-binding cassette domain similar to the molybdate transporter; Archaeal protein closely ... |
4-244 |
1.55e-78 |
|
ATP-binding cassette domain similar to the molybdate transporter; Archaeal protein closely related to ModC. ModC is an ABC-type transporter and the ATPase component of a molybdate transport system that also includes the periplasmic binding protein ModA and the membrane protein ModB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213266 [Multi-domain] Cd Length: 235 Bit Score: 241.47 E-value: 1.55e-78
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 4 ISLRGVQKAYGDGapVIRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLSIGGKIMNDVPAAQRGVAMVFQ 83
Cdd:cd03299 1 LKVENLSKDWKEF--KLKNVSLEVERGDYFVILGPTGSGKSVLLETIAGFIKPDSGKILLNGKDITNLPPEKRDISYVPQ 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 84 SYALFPHMTVFENMAFGLKLAKTPKEEIDRKVREAARVLQLEALLERRPKALSGGQRQRVAIGRAIVRQPGVFLFDEPLS 163
Cdd:cd03299 79 NYALFPHMTVYKNIAYGLKKRKVDKKEIERKVLEIAEMLGIDHLLNRKPETLSGGEQQRVAIARALVVNPKILLLDEPFS 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 164 NLDATLRGQTRIEIARLHKQFaKASVVYVTHDQIEAMTLADKIVLLHAGKdterygsIAQIGAPLELYHRPKSRFVAGFI 243
Cdd:cd03299 159 ALDVRTKEKLREELKKIRKEF-GVTVLHVTHDFEEAWALADKVAIMLNGK-------LIQVGKPEEVFKKPKNEFVAEFL 230
|
.
gi 928002514 244 G 244
Cdd:cd03299 231 G 231
|
|
| ABC_NrtD_SsuB_transporters |
cd03293 |
ATP-binding cassette domain of the nitrate and sulfonate transporters; NrtD and SsuB are the ... |
4-211 |
1.02e-75 |
|
ATP-binding cassette domain of the nitrate and sulfonate transporters; NrtD and SsuB are the ATP-binding subunits of the bacterial ABC-type nitrate and sulfonate transport systems, respectively. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213260 [Multi-domain] Cd Length: 220 Bit Score: 233.52 E-value: 1.02e-75
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 4 ISLRGVQKAYGDGA---PVIRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLSIGGKIMNDVPAAqrgVAM 80
Cdd:cd03293 1 LEVRNVSKTYGGGGgavTALEDISLSVEEGEFVALVGPSGCGKSTLLRIIAGLERPTSGEVLVDGEPVTGPGPD---RGY 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 81 VFQSYALFPHMTVFENMAFGLKLAKTPKEEIDRKVREAARVLQLEALLERRPKALSGGQRQRVAIGRAIVRQPGVFLFDE 160
Cdd:cd03293 78 VFQQDALLPWLTVLDNVALGLELQGVPKAEARERAEELLELVGLSGFENAYPHQLSGGMRQRVALARALAVDPDVLLLDE 157
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 928002514 161 PLSNLDATLRGQTRIEIARLHKQfAKASVVYVTHDQIEAMTLADKIVLLHA 211
Cdd:cd03293 158 PFSALDALTREQLQEELLDIWRE-TGKTVLLVTHDIDEAVFLADRVVVLSA 207
|
|
| potG |
PRK11607 |
putrescine ABC transporter ATP-binding subunit PotG; |
4-302 |
1.09e-74 |
|
putrescine ABC transporter ATP-binding subunit PotG;
Pssm-ID: 183226 [Multi-domain] Cd Length: 377 Bit Score: 236.66 E-value: 1.09e-74
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 4 ISLRGVQKAYgDGAPVIRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLSIGGKIMNDVPAAQRGVAMVFQ 83
Cdd:PRK11607 20 LEIRNLTKSF-DGQHAVDDVSLTIYKGEIFALLGASGCGKSTLLRMLAGFEQPTAGQIMLDGVDLSHVPPYQRPINMMFQ 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 84 SYALFPHMTVFENMAFGLKLAKTPKEEIDRKVREAARVLQLEALLERRPKALSGGQRQRVAIGRAIVRQPGVFLFDEPLS 163
Cdd:PRK11607 99 SYALFPHMTVEQNIAFGLKQDKLPKAEIASRVNEMLGLVHMQEFAKRKPHQLSGGQRQRVALARSLAKRPKLLLLDEPMG 178
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 164 NLDATLRGQTRIEIARLHKQFAkASVVYVTHDQIEAMTLADKIVLLHAGKdterygsIAQIGAPLELYHRPKSRFVAGFI 243
Cdd:PRK11607 179 ALDKKLRDRMQLEVVDILERVG-VTCVMVTHDQEEAMTMAGRIAIMNRGK-------FVQIGEPEEIYEHPTTRYSAEFI 250
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*....
gi 928002514 244 GSprMNFLPGRVASVDAQGVIVTLDTTLENVRVPVDGAALEvAQPVTLGVRPEHLEFID 302
Cdd:PRK11607 251 GS--VNVFEGVLKERQEDGLVIDSPGLVHPLKVDADASVVD-NVPVHVALRPEKIMLCE 306
|
|
| PhnT |
TIGR03258 |
2-aminoethylphosphonate ABC transport system, ATP-binding component PhnT; This ATP-binding ... |
4-358 |
1.37e-72 |
|
2-aminoethylphosphonate ABC transport system, ATP-binding component PhnT; This ATP-binding component of an ABC transport system is found in Salmonella and Burkholderia lineages in the vicinity of enzymes for the breakdown of 2-aminoethylphosphonate.
Pssm-ID: 132302 [Multi-domain] Cd Length: 362 Bit Score: 230.65 E-value: 1.37e-72
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 4 ISLRGVQKAYGdGAPVIRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGL--EDLTDGDLSIGGKIMNDVPAAQRGVAMV 81
Cdd:TIGR03258 6 IRIDHLRVAYG-ANTVLDDLSLEIEAGELLALIGKSGCGKTTLLRAIAGFvkAAGLTGRIAIADRDLTHAPPHKRGLALL 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 82 FQSYALFPHMTVFENMAFGLKLAKTPKEEIDRKVREAARVLQLEALLERRPKALSGGQRQRVAIGRAIVRQPGVFLFDEP 161
Cdd:TIGR03258 85 FQNYALFPHLKVEDNVAFGLRAQKMPKADIAERVADALKLVGLGDAAAHLPAQLSGGMQQRIAIARAIAIEPDVLLLDEP 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 162 LSNLDATLRGQTRIEIARLHKQFAKASVVYVTHDQIEAMTLADKIVLLhagkdteRYGSIAQIGAPLELYHRPKSRFVAG 241
Cdd:TIGR03258 165 LSALDANIRANMREEIAALHEELPELTILCVTHDQDDALTLADKAGIM-------KDGRLAAHGEPQALYDAPADGFAAE 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 242 FIGspRMNFLPGRVASVDAQGVIVTLDTTLENVRVPVDGAalEVAQPVTLGVRPEHLEFIDTSSLQDEavLTRTVSLVEQ 321
Cdd:TIGR03258 238 FLG--AANILPAIALGITEAPGLVDVSCGGAVIFAFGDGR--HDGRDKLACIRPEHLALTPRPAGEGR--FHATIASVEW 311
|
330 340 350
....*....|....*....|....*....|....*..
gi 928002514 322 LGEHSYVHLDQPGGFTLIAKAPGDTHLAPGDRAHLRV 358
Cdd:TIGR03258 312 HGAALHLLCDLDAACDEPMLVTMLRGRGPAPERGAKL 348
|
|
| ABC_OpuCA_Osmoprotection |
cd03295 |
ATP-binding cassette domain of the osmoprotectant transporter; OpuCA is a the ATP binding ... |
4-247 |
3.39e-72 |
|
ATP-binding cassette domain of the osmoprotectant transporter; OpuCA is a the ATP binding component of a bacterial solute transporter that serves a protective role to cells growing in a hyperosmolar environment. ABC (ATP-binding cassette) transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition, to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213262 [Multi-domain] Cd Length: 242 Bit Score: 225.64 E-value: 3.39e-72
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 4 ISLRGVQKAYGDGAPVIRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLSIGGKIMNDVPAAQ--RGVAMV 81
Cdd:cd03295 1 IEFENVTKRYGGGKKAVNNLNLEIAKGEFLVLIGPSGSGKTTTMKMINRLIEPTSGEIFIDGEDIREQDPVElrRKIGYV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 82 FQSYALFPHMTVFENMAFGLKLAKTPKEEIDRKVREAARVLQLE--ALLERRPKALSGGQRQRVAIGRAIVRQPGVFLFD 159
Cdd:cd03295 81 IQQIGLFPHMTVEENIALVPKLLKWPKEKIRERADELLALVGLDpaEFADRYPHELSGGQQQRVGVARALAADPPLLLMD 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 160 EPLSNLDATLRGQTRIEIARLHKQFAKaSVVYVTHDQIEAMTLADKIVLLHAGKdterygsIAQIGAPLELYHRPKSRFV 239
Cdd:cd03295 161 EPFGALDPITRDQLQEEFKRLQQELGK-TIVFVTHDIDEAFRLADRIAIMKNGE-------IVQVGTPDEILRSPANDFV 232
|
....*...
gi 928002514 240 AGFIGSPR 247
Cdd:cd03295 233 AEFVGADR 240
|
|
| PRK10851 |
PRK10851 |
sulfate/thiosulfate ABC transporter ATP-binding protein CysA; |
3-255 |
6.52e-70 |
|
sulfate/thiosulfate ABC transporter ATP-binding protein CysA;
Pssm-ID: 182778 [Multi-domain] Cd Length: 353 Bit Score: 223.42 E-value: 6.52e-70
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 3 SISLRGVQKAYGDGApVIRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLSIGGKIMNDVPAAQRGVAMVF 82
Cdd:PRK10851 2 SIEIANIKKSFGRTQ-VLNDISLDIPSGQMVALLGPSGSGKTTLLRIIAGLEHQTSGHIRFHGTDVSRLHARDRKVGFVF 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 83 QSYALFPHMTVFENMAFGLKL---AKTP-KEEIDRKVREAARVLQLEALLERRPKALSGGQRQRVAIGRAIVRQPGVFLF 158
Cdd:PRK10851 81 QHYALFRHMTVFDNIAFGLTVlprRERPnAAAIKAKVTQLLEMVQLAHLADRYPAQLSGGQKQRVALARALAVEPQILLL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 159 DEPLSNLDATLRGQTRIEIARLHKQFaKASVVYVTHDQIEAMTLADKIVLLhagkdteRYGSIAQIGAPLELYHRPKSRF 238
Cdd:PRK10851 161 DEPFGALDAQVRKELRRWLRQLHEEL-KFTSVFVTHDQEEAMEVADRVVVM-------SQGNIEQAGTPDQVWREPATRF 232
|
250
....*....|....*..
gi 928002514 239 VAGFIGSprMNFLPGRV 255
Cdd:PRK10851 233 VLEFMGE--VNRLQGTI 247
|
|
| ModC |
COG4148 |
ABC-type molybdate transport system, ATPase component ModC [Inorganic ion transport and ... |
22-355 |
9.20e-65 |
|
ABC-type molybdate transport system, ATPase component ModC [Inorganic ion transport and metabolism]; ABC-type molybdate transport system, ATPase component ModC is part of the Pathway/BioSystem: Molybdopterin biosynthesis
Pssm-ID: 443319 [Multi-domain] Cd Length: 358 Bit Score: 209.96 E-value: 9.20e-65
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 22 DVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLSIGGKIMND------VPAAQRGVAMVFQSYALFPHMTVFE 95
Cdd:COG4148 17 DVDFTLPGRGVTALFGPSGSGKTTLLRAIAGLERPDSGRIRLGGEVLQDsargifLPPHRRRIGYVFQEARLFPHLSVRG 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 96 NMAFGLKLAKTPKEEIDrkVREAARVLQLEALLERRPKALSGGQRQRVAIGRAIVRQPGVFLFDEPLSNLDATLRGQTRI 175
Cdd:COG4148 97 NLLYGRKRAPRAERRIS--FDEVVELLGIGHLLDRRPATLSGGERQRVAIGRALLSSPRLLLMDEPLAALDLARKAEILP 174
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 176 EIARLHKQFAkASVVYVTHDQIEAMTLADKIVLLHAGKdterygsIAQIGAPLELYHRPKSRFVAGfiGSPRMNFLPGRV 255
Cdd:COG4148 175 YLERLRDELD-IPILYVSHSLDEVARLADHVVLLEQGR-------VVASGPLAEVLSRPDLLPLAG--GEEAGSVLEATV 244
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 256 ASVDAQGVIVTLDTTLENVRVPvdGAALEVAQPVTLGVRPEH----LEFIDTSSLQDeaVLT-RTVSLVEQLGEHSYVHL 330
Cdd:COG4148 245 AAHDPDYGLTRLALGGGRLWVP--RLDLPPGTRVRVRIRARDvslaLEPPEGSSILN--ILPgRVVEIEPADGGQVLVRL 320
|
330 340
....*....|....*....|....*....
gi 928002514 331 DqPGGFTLIA----KAPGDTHLAPGDRAH 355
Cdd:COG4148 321 D-LGGQTLLAritrRSADELGLAPGQTVY 348
|
|
| LolD |
COG1136 |
ABC-type lipoprotein export system, ATPase component [Cell wall/membrane/envelope biogenesis]; |
1-213 |
5.81e-63 |
|
ABC-type lipoprotein export system, ATPase component [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440751 [Multi-domain] Cd Length: 227 Bit Score: 201.04 E-value: 5.81e-63
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 1 MAS-ISLRGVQKAYGDGA---PVIRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLSIGGKIMNDVPAAQR 76
Cdd:COG1136 1 MSPlLELRNLTKSYGTGEgevTALRGVSLSIEAGEFVAIVGPSGSGKSTLLNILGGLDRPTSGEVLIDGQDISSLSEREL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 77 G------VAMVFQSYALFPHMTVFENMAFGLKLAKTPKEEIDRKVREAARVLQLEALLERRPKALSGGQRQRVAIGRAIV 150
Cdd:COG1136 81 ArlrrrhIGFVFQFFNLLPELTALENVALPLLLAGVSRKERRERARELLERVGLGDRLDHRPSQLSGGQQQRVAIARALV 160
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 928002514 151 RQPGVFLFDEPLSNLDAtlrgQTRIEIARLHKQFAK---ASVVYVTHDQiEAMTLADKIVLLHAGK 213
Cdd:COG1136 161 NRPKLILADEPTGNLDS----KTGEEVLELLRELNRelgTTIVMVTHDP-ELAARADRVIRLRDGR 221
|
|
| ABC_Class3 |
cd03229 |
ATP-binding cassette domain of the binding protein-dependent transport systems; This class is ... |
4-213 |
4.77e-61 |
|
ATP-binding cassette domain of the binding protein-dependent transport systems; This class is comprised of all BPD (Binding Protein Dependent) systems that are largely represented in archaea and eubacteria and are primarily involved in scavenging solutes from the environment. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213196 [Multi-domain] Cd Length: 178 Bit Score: 194.33 E-value: 4.77e-61
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 4 ISLRGVQKAYGdGAPVIRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLSIGGKIMND----VPAAQRGVA 79
Cdd:cd03229 1 LELKNVSKRYG-QKTVLNDVSLNIEAGEIVALLGPSGSGKSTLLRCIAGLEEPDSGSILIDGEDLTDledeLPPLRRRIG 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 80 MVFQSYALFPHMTVFENMAFGlklaktpkeeidrkvreaarvlqleallerrpkaLSGGQRQRVAIGRAIVRQPGVFLFD 159
Cdd:cd03229 80 MVFQDFALFPHLTVLENIALG----------------------------------LSGGQQQRVALARALAMDPDVLLLD 125
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 928002514 160 EPLSNLDATLRGQTRIEIARLHKQFAKAsVVYVTHDQIEAMTLADKIVLLHAGK 213
Cdd:cd03229 126 EPTSALDPITRREVRALLKSLQAQLGIT-VVLVTHDLDEAARLADRVVVLRDGK 178
|
|
| ABC_MJ0796_LolCDE_FtsE |
cd03255 |
ATP-binding cassette domain of the transporters involved in export of lipoprotein and ... |
4-213 |
8.20e-60 |
|
ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and Cell division ATP-binding protein FtsE; This family is comprised of MJ0796 ATP-binding cassette, macrolide-specific ABC-type efflux carrier (MacAB), and proteins involved in cell division (FtsE), and release of lipoproteins from the cytoplasmic membrane (LolCDE). They are clustered together phylogenetically. MacAB is an exporter that confers resistance to macrolides, while the LolCDE system is not a transporter at all. The FtsEX complex resembles an ABC transporter, where FtsE is the ATPase and the membrane subunit FtsX resembles a permease subunit. But rather than transporting any substrate, the complex acts in cell division by undergoing conformational changes that alter the activity of cell wall hydrolases located outside the plasma membrane. The complex is widely conserved in bacteria, but also extremely divergent in sequence between different lineages. The LolCDE complex catalyzes the release of lipoproteins from the cytoplasmic membrane prior to their targeting to the outer membrane.
Pssm-ID: 213222 [Multi-domain] Cd Length: 218 Bit Score: 192.70 E-value: 8.20e-60
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 4 ISLRGVQKAYGDGA---PVIRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLSIGGKIMNDVPAAQRG--- 77
Cdd:cd03255 1 IELKNLSKTYGGGGekvQALKGVSLSIEKGEFVAIVGPSGSGKSTLLNILGGLDRPTSGEVRVDGTDISKLSEKELAafr 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 78 ---VAMVFQSYALFPHMTVFENMAFGLKLAKTPKEEIDRKVREAARVLQLEALLERRPKALSGGQRQRVAIGRAIVRQPG 154
Cdd:cd03255 81 rrhIGFVFQSFNLLPDLTALENVELPLLLAGVPKKERRERAEELLERVGLGDRLNHYPSELSGGQQQRVAIARALANDPK 160
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 928002514 155 VFLFDEPLSNLDAtlrgQTRIEIARLHKQFAK---ASVVYVTHDQiEAMTLADKIVLLHAGK 213
Cdd:cd03255 161 IILADEPTGNLDS----ETGKEVMELLRELNKeagTTIVVVTHDP-ELAEYADRIIELRDGK 217
|
|
| ABC_Pro_Gly_Betaine |
cd03294 |
ATP-binding cassette domain of the osmoprotectant proline/glycine betaine uptake system; This ... |
20-243 |
1.26e-59 |
|
ATP-binding cassette domain of the osmoprotectant proline/glycine betaine uptake system; This family comprises the glycine betaine/L-proline ATP binding subunit in bacteria and its equivalents in archaea. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporters is the obligatory coupling of ATP hydrolysis to substrate translocation. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213261 [Multi-domain] Cd Length: 269 Bit Score: 194.01 E-value: 1.26e-59
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 20 IRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLSIGGKIMNDVPAAQ------RGVAMVFQSYALFPHMTV 93
Cdd:cd03294 40 VNDVSLDVREGEIFVIMGLSGSGKSTLLRCINRLIEPTSGKVLIDGQDIAAMSRKElrelrrKKISMVFQSFALLPHRTV 119
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 94 FENMAFGLKLAKTPKEEIDRKVREAARVLQLEALLERRPKALSGGQRQRVAIGRAIVRQPGVFLFDEPLSNLDATLRGQT 173
Cdd:cd03294 120 LENVAFGLEVQGVPRAEREERAAEALELVGLEGWEHKYPDELSGGMQQRVGLARALAVDPDILLMDEAFSALDPLIRREM 199
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 174 RIEIARLHKQFAKaSVVYVTHDQIEAMTLADKIVLLhagKDteryGSIAQIGAPLELYHRPKSRFVAGFI 243
Cdd:cd03294 200 QDELLRLQAELQK-TIVFITHDLDEALRLGDRIAIM---KD----GRLVQVGTPEEILTNPANDYVREFF 261
|
|
| proV |
TIGR01186 |
glycine betaine/L-proline transport ATP binding subunit; This model describes the glycine ... |
20-271 |
2.04e-59 |
|
glycine betaine/L-proline transport ATP binding subunit; This model describes the glycine betaine/L-proline ATP binding subunit in bacteria and its equivalents in archaea. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporter is the obligatory coupling of ATP hydrolysis to substrate translocation. The minimal configuration of bacterial ABC transport system: an ATPase or ATP binding subunit; An integral membrane protein; a hydrophilic polypetpide, which likely functions as substrate binding protein. Functionally, this transport system is involved in osmoregulation. Under conditions of stress, the organism recruits these transport system to accumulate glycine betaine and other solutes which offer osmo-protection. It has been demonstrated that glycine betaine uptake is accompanied by symport with sodium ions. The locus has been named variously as proU or opuA. A gene library from L.lactis functionally complements an E.coli proU mutant. The comlementing locus is similar to a opuA locus in B.sutlis. This clarifies the differences in nomenclature. [Transport and binding proteins, Amino acids, peptides and amines]
Pssm-ID: 130254 [Multi-domain] Cd Length: 363 Bit Score: 196.61 E-value: 2.04e-59
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 20 IRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLSIGGK-IMNDVPA-----AQRGVAMVFQSYALFPHMTV 93
Cdd:TIGR01186 9 VNDADLAIAKGEIFVIMGLSGSGKSTTVRMLNRLIEPTAGQIFIDGEnIMKQSPVelrevRRKKIGMVFQQFALFPHMTI 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 94 FENMAFGLKLAKTPKEEIDRKVREAARVLQLEALLERRPKALSGGQRQRVAIGRAIVRQPGVFLFDEPLSNLDATLRGQT 173
Cdd:TIGR01186 89 LQNTSLGPELLGWPEQERKEKALELLKLVGLEEYEHRYPDELSGGMQQRVGLARALAAEPDILLMDEAFSALDPLIRDSM 168
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 174 RIEIARLHKQFAKaSVVYVTHDQIEAMTLADKIVLLHAGKdterygsIAQIGAPLELYHRPKSRFVAGFIGSPRMN--FL 251
Cdd:TIGR01186 169 QDELKKLQATLQK-TIVFITHDLDEAIRIGDRIVIMKAGE-------IVQVGTPDEILRNPANEYVEEFIGKVDLSqvFD 240
|
250 260
....*....|....*....|.
gi 928002514 252 PGRVAS-VDAQGVIVTLDTTL 271
Cdd:TIGR01186 241 AERIAQrMNTGPITKTADKGP 261
|
|
| ABC_ModC_molybdenum_transporter |
cd03297 |
ATP-binding cassette domain of the molybdenum transport system; ModC is an ABC-type ... |
22-213 |
4.16e-59 |
|
ATP-binding cassette domain of the molybdenum transport system; ModC is an ABC-type transporter and the ATPase component of a molybdate transport system that also includes the periplasmic binding protein ModA and the membrane protein ModB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213264 [Multi-domain] Cd Length: 214 Bit Score: 190.97 E-value: 4.16e-59
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 22 DVDLEIGEnEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLSIGGKIMND------VPAAQRGVAMVFQSYALFPHMTVFE 95
Cdd:cd03297 16 KIDFDLNE-EVTGIFGASGAGKSTLLRCIAGLEKPDGGTIVLNGTVLFDsrkkinLPPQQRKIGLVFQQYALFPHLNVRE 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 96 NMAFGLKlAKTPKEEIDRkVREAARVLQLEALLERRPKALSGGQRQRVAIGRAIVRQPGVFLFDEPLSNLDATLRGQTRI 175
Cdd:cd03297 95 NLAFGLK-RKRNREDRIS-VDELLDLLGLDHLLNRYPAQLSGGEKQRVALARALAAQPELLLLDEPFSALDRALRLQLLP 172
|
170 180 190
....*....|....*....|....*....|....*...
gi 928002514 176 EIARLHKQFaKASVVYVTHDQIEAMTLADKIVLLHAGK 213
Cdd:cd03297 173 ELKQIKKNL-NIPVIFVTHDLSEAEYLADRIVVMEDGR 209
|
|
| EcfA2 |
COG1122 |
Energy-coupling factor transporter ATP-binding protein EcfA2 [Inorganic ion transport and ... |
4-235 |
8.07e-59 |
|
Energy-coupling factor transporter ATP-binding protein EcfA2 [Inorganic ion transport and metabolism, General function prediction only];
Pssm-ID: 440739 [Multi-domain] Cd Length: 230 Bit Score: 190.62 E-value: 8.07e-59
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 4 ISLRGVQKAYGDGAPVIRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLSIGGKIMNDVPAAQ--RGVAMV 81
Cdd:COG1122 1 IELENLSFSYPGGTPALDDVSLSIEKGEFVAIIGPNGSGKSTLLRLLNGLLKPTSGEVLVDGKDITKKNLRElrRKVGLV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 82 FQS--YALFpHMTVFENMAFGLKLAKTPKEEIDRKVREAARVLQLEALLERRPKALSGGQRQRVAIGRAIVRQPGVFLFD 159
Cdd:COG1122 81 FQNpdDQLF-APTVEEDVAFGPENLGLPREEIRERVEEALELVGLEHLADRPPHELSGGQKQRVAIAGVLAMEPEVLVLD 159
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 928002514 160 EPLSNLDatLRGQTRIE--IARLHKQfaKASVVYVTHDQIEAMTLADKIVLLHAGKdterygsIAQIGAPLELYHRPK 235
Cdd:COG1122 160 EPTAGLD--PRGRRELLelLKRLNKE--GKTVIIVTHDLDLVAELADRVIVLDDGR-------IVADGTPREVFSDYE 226
|
|
| FtsE |
COG2884 |
Cell division ATPase FtsE [Cell cycle control, cell division, chromosome partitioning]; |
4-213 |
3.03e-58 |
|
Cell division ATPase FtsE [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 442130 [Multi-domain] Cd Length: 223 Bit Score: 188.72 E-value: 3.03e-58
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 4 ISLRGVQKAYGDGAPVIRDVDLEIGENEFcVFL-GPSGCGKSTLLCMIAGLEDLTDGDLSIGGKIMN-----DVPAAQRG 77
Cdd:COG2884 2 IRFENVSKRYPGGREALSDVSLEIEKGEF-VFLtGPSGAGKSTLLKLLYGEERPTSGQVLVNGQDLSrlkrrEIPYLRRR 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 78 VAMVFQSYALFPHMTVFENMAFGLKLAKTPKEEIDRKVREAARVLQLEALLERRPKALSGGQRQRVAIGRAIVRQPGVFL 157
Cdd:COG2884 81 IGVVFQDFRLLPDRTVYENVALPLRVTGKSRKEIRRRVREVLDLVGLSDKAKALPHELSGGEQQRVAIARALVNRPELLL 160
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 158 FDEPLSNLDAtlrgQTRIEIARLHKQFAKA--SVVYVTHDQ--IEAMtlADKIVLLHAGK 213
Cdd:COG2884 161 ADEPTGNLDP----ETSWEIMELLEEINRRgtTVLIATHDLelVDRM--PKRVLELEDGR 214
|
|
| ThiQ |
COG3840 |
ABC-type thiamine transport system, ATPase component ThiQ [Coenzyme transport and metabolism]; |
4-213 |
1.56e-56 |
|
ABC-type thiamine transport system, ATPase component ThiQ [Coenzyme transport and metabolism];
Pssm-ID: 443051 [Multi-domain] Cd Length: 232 Bit Score: 184.57 E-value: 1.56e-56
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 4 ISLRGVQKAYGDgapVIRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLSIGGKIMNDVPAAQRGVAMVFQ 83
Cdd:COG3840 2 LRLDDLTYRYGD---FPLRFDLTIAAGERVAILGPSGAGKSTLLNLIAGFLPPDSGRILWNGQDLTALPPAERPVSMLFQ 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 84 SYALFPHMTVFENMAFG----LKLAKTPKEeidrKVREAARVLQLEALLERRPKALSGGQRQRVAIGRAIVRQPGVFLFD 159
Cdd:COG3840 79 ENNLFPHLTVAQNIGLGlrpgLKLTAEQRA----QVEQALERVGLAGLLDRLPGQLSGGQRQRVALARCLVRKRPILLLD 154
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 928002514 160 EPLSNLDATLRGQTRIEIARLHKQFaKASVVYVTHDQIEAMTLADKIVLLHAGK 213
Cdd:COG3840 155 EPFSALDPALRQEMLDLVDELCRER-GLTVLMVTHDPEDAARIADRVLLVADGR 207
|
|
| GlnQ |
COG1126 |
ABC-type polar amino acid transport system, ATPase component [Amino acid transport and ... |
4-236 |
3.97e-56 |
|
ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 440743 [Multi-domain] Cd Length: 239 Bit Score: 184.04 E-value: 3.97e-56
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 4 ISLRGVQKAYGDgAPVIRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLSIGGKIMN----DVPAAQRGVA 79
Cdd:COG1126 2 IEIENLHKSFGD-LEVLKGISLDVEKGEVVVIIGPSGSGKSTLLRCINLLEEPDSGTITVDGEDLTdskkDINKLRRKVG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 80 MVFQSYALFPHMTVFENMAFGL-KLAKTPKEEIDRKVREA-ARVlQLEALLERRPKALSGGQRQRVAIGRAIVRQPGVFL 157
Cdd:COG1126 81 MVFQQFNLFPHLTVLENVTLAPiKVKKMSKAEAEERAMELlERV-GLADKADAYPAQLSGGQQQRVAIARALAMEPKVML 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 158 FDEPLSNLDATLRGqtriEIARLHKQFAKA--SVVYVTHDQIEAMTLADKIVLLHAGKdterygsIAQIGAPLELYHRPK 235
Cdd:COG1126 160 FDEPTSALDPELVG----EVLDVMRDLAKEgmTMVVVTHEMGFAREVADRVVFMDGGR-------IVEEGPPEEFFENPQ 228
|
.
gi 928002514 236 S 236
Cdd:COG1126 229 H 229
|
|
| ABC_cobalt_CbiO_domain1 |
cd03225 |
First domain of the ATP-binding cassette component of cobalt transport system; Domain I of the ... |
5-213 |
6.83e-56 |
|
First domain of the ATP-binding cassette component of cobalt transport system; Domain I of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota. The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed. This ABC transport system of the CbiMNQO family is involved in cobalt transport in association with the cobalamin (vitamin B12) biosynthetic pathways. Most of cobalt (Cbi) transport systems possess a separate CbiN component, the cobalt-binding periplasmic protein, and they are encoded by the conserved gene cluster cbiMNQO. Both the CbiM and CbiQ proteins are integral cytoplasmic membrane proteins, and the CbiO protein has the linker peptide and the Walker A and B motifs commonly found in the ATPase components of the ABC-type transport systems.
Pssm-ID: 213192 [Multi-domain] Cd Length: 211 Bit Score: 182.28 E-value: 6.83e-56
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 5 SLRGVQKAYGDGA-PVIRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLSIGGKIMNDVPAAQRG--VAMV 81
Cdd:cd03225 1 ELKNLSFSYPDGArPALDDISLTIKKGEFVLIVGPNGSGKSTLLRLLNGLLGPTSGEVLVDGKDLTKLSLKELRrkVGLV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 82 FQsyalFP-HM----TVFENMAFGLKLAKTPKEEIDRKVREAARVLQLEALLERRPKALSGGQRQRVAIGRAIVRQPGVF 156
Cdd:cd03225 81 FQ----NPdDQffgpTVEEEVAFGLENLGLPEEEIEERVEEALELVGLEGLRDRSPFTLSGGQKQRVAIAGVLAMDPDIL 156
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 928002514 157 LFDEPLSNLDATLRGQTRIEIARLHKQfaKASVVYVTHDQIEAMTLADKIVLLHAGK 213
Cdd:cd03225 157 LLDEPTAGLDPAGRRELLELLKKLKAE--GKTIIIVTHDLDLLLELADRVIVLEDGK 211
|
|
| TauB |
COG4525 |
ABC-type taurine transport system, ATPase component [Inorganic ion transport and metabolism]; |
1-218 |
5.64e-54 |
|
ABC-type taurine transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 443596 [Multi-domain] Cd Length: 262 Bit Score: 179.29 E-value: 5.64e-54
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 1 MASISLRGVQKAYGDGA---PVIRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLSIGGKIMNDvPAAQRG 77
Cdd:COG4525 1 MSMLTVRHVSVRYPGGGqpqPALQDVSLTIESGEFVVALGASGCGKTTLLNLIAGFLAPSSGEITLDGVPVTG-PGADRG 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 78 VamVFQSYALFPHMTVFENMAFGLKLAKTPKEEIDRKVREAARVLQLEALLERRPKALSGGQRQRVAIGRAIVRQPGVFL 157
Cdd:COG4525 80 V--VFQKDALLPWLNVLDNVAFGLRLRGVPKAERRARAEELLALVGLADFARRRIWQLSGGMRQRVGIARALAADPRFLL 157
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 928002514 158 FDEPLSNLDATLRGQTRIEIARLHKQFAKaSVVYVTHDQIEAMTLADKIVLL--HAGKDTERY 218
Cdd:COG4525 158 MDEPFGALDALTREQMQELLLDVWQRTGK-GVFLITHSVEEALFLATRLVVMspGPGRIVERL 219
|
|
| ProV |
COG4175 |
ABC-type proline/glycine betaine transport system, ATPase component [Amino acid transport and ... |
20-243 |
4.41e-53 |
|
ABC-type proline/glycine betaine transport system, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 443334 [Multi-domain] Cd Length: 389 Bit Score: 180.68 E-value: 4.41e-53
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 20 IRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLSIGGKIMNDVPAAQ------RGVAMVFQSYALFPHMTV 93
Cdd:COG4175 43 VNDASFDVEEGEIFVIMGLSGSGKSTLVRCLNRLIEPTAGEVLIDGEDITKLSKKElrelrrKKMSMVFQHFALLPHRTV 122
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 94 FENMAFGLKLAKTPKEEIDRKVREAARVLQLEALLERRPKALSGGQRQRVAIGRAIVRQPGVFLFDEPLSNLDATLRGQT 173
Cdd:COG4175 123 LENVAFGLEIQGVPKAERRERAREALELVGLAGWEDSYPDELSGGMQQRVGLARALATDPDILLMDEAFSALDPLIRREM 202
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 174 RIEIARLHKQFAKaSVVYVTHDQIEAMTLADKIVLLhagKDteryGSIAQIGAPLELYHRPKSRFVAGFI 243
Cdd:COG4175 203 QDELLELQAKLKK-TIVFITHDLDEALRLGDRIAIM---KD----GRIVQIGTPEEILTNPANDYVADFV 264
|
|
| MlaF |
COG1127 |
ATPase subunit MlaF of the ABC-type intermembrane phospholipid transporter Mla [Cell wall ... |
4-213 |
1.30e-52 |
|
ATPase subunit MlaF of the ABC-type intermembrane phospholipid transporter Mla [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440744 [Multi-domain] Cd Length: 241 Bit Score: 174.78 E-value: 1.30e-52
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 4 ISLRGVQKAYGDgAPVIRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLSIGGKIMNDVPAAQ-----RGV 78
Cdd:COG1127 6 IEVRNLTKSFGD-RVVLDGVSLDVPRGEILAIIGGSGSGKSVLLKLIIGLLRPDSGEILVDGQDITGLSEKElyelrRRI 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 79 AMVFQSYALFPHMTVFENMAFGLK-LAKTPKEEIDRKVREAARVLQLEALLERRPKALSGGQRQRVAIGRAIVRQPGVFL 157
Cdd:COG1127 85 GMLFQGGALFDSLTVFENVAFPLReHTDLSEAEIRELVLEKLELVGLPGAADKMPSELSGGMRKRVALARALALDPEILL 164
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 928002514 158 FDEPLSNLDAtlRGQTRIE--IARLHKQFaKASVVYVTHDQIEAMTLADKIVLLHAGK 213
Cdd:COG1127 165 YDEPTAGLDP--ITSAVIDelIRELRDEL-GLTSVVVTHDLDSAFAIADRVAVLADGK 219
|
|
| ABC_HisP_GlnQ |
cd03262 |
ATP-binding cassette domain of the histidine and glutamine transporters; HisP and GlnQ are the ... |
4-213 |
1.53e-52 |
|
ATP-binding cassette domain of the histidine and glutamine transporters; HisP and GlnQ are the ATP-binding components of the bacterial periplasmic histidine and glutamine permeases, respectively. Histidine permease is a multi-subunit complex containing the HisQ and HisM integral membrane subunits and two copies of HisP. HisP has properties intermediate between those of integral and peripheral membrane proteins and is accessible from both sides of the membrane, presumably by its interaction with HisQ and HisM. The two HisP subunits form a homodimer within the complex. The domain structure of the amino acid uptake systems is typical for prokaryotic extracellular solute binding protein-dependent uptake systems. All of the amino acid uptake systems also have at least one, and in a few cases, two extracellular solute binding proteins located in the periplasm of Gram-negative bacteria, or attached to the cell membrane of Gram-positive bacteria. The best-studied member of the PAAT (polar amino acid transport) family is the HisJQMP system of S. typhimurium, where HisJ is the extracellular solute binding proteins and HisP is the ABC protein.
Pssm-ID: 213229 [Multi-domain] Cd Length: 213 Bit Score: 173.87 E-value: 1.53e-52
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 4 ISLRGVQKAYGDgAPVIRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLSIGGKIMN----DVPAAQRGVA 79
Cdd:cd03262 1 IEIKNLHKSFGD-FHVLKGIDLTVKKGEVVVIIGPSGSGKSTLLRCINLLEEPDSGTIIIDGLKLTddkkNINELRQKVG 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 80 MVFQSYALFPHMTVFENMAFGL-KLAKTPKEEIDRKVREAARVLQLEALLERRPKALSGGQRQRVAIGRAIVRQPGVFLF 158
Cdd:cd03262 80 MVFQQFNLFPHLTVLENITLAPiKVKGMSKAEAEERALELLEKVGLADKADAYPAQLSGGQQQRVAIARALAMNPKVMLF 159
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 928002514 159 DEPLSNLDATLRGqtriEIARLHKQFAKA--SVVYVTHDQIEAMTLADKIVLLHAGK 213
Cdd:cd03262 160 DEPTSALDPELVG----EVLDVMKDLAEEgmTMVVVTHEMGFAREVADRVIFMDDGR 212
|
|
| ABC_PstB_phosphate_transporter |
cd03260 |
ATP-binding cassette domain of the phosphate transport system; Phosphate uptake is of ... |
4-224 |
4.50e-52 |
|
ATP-binding cassette domain of the phosphate transport system; Phosphate uptake is of fundamental importance in the cell physiology of bacteria because phosphate is required as a nutrient. The Pst system of E. coli comprises four distinct subunits encoded by the pstS, pstA, pstB, and pstC genes. The PstS protein is a phosphate-binding protein located in the periplasmic space. PstA and PstC are hydrophobic and they form the transmembrane portion of the Pst system. PstB is the catalytic subunit, which couples the energy of ATP hydrolysis to the import of phosphate across cellular membranes through the Pst system, often referred as ABC-protein. PstB belongs to one of the largest superfamilies of proteins characterized by a highly conserved adenosine triphosphate (ATP) binding cassette (ABC), which is also a nucleotide binding domain (NBD).
Pssm-ID: 213227 [Multi-domain] Cd Length: 227 Bit Score: 173.14 E-value: 4.50e-52
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 4 ISLRGVQKAYGDGApVIRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDL-----TDGDLSIGGK----IMNDVPAA 74
Cdd:cd03260 1 IELRDLNVYYGDKH-ALKDISLDIPKGEITALIGPSGCGKSTLLRLLNRLNDLipgapDEGEVLLDGKdiydLDVDVLEL 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 75 QRGVAMVFQSYALFPhMTVFENMAFGLKLAKT-PKEEIDRKVREAARVLQLEALLERRPKA--LSGGQRQRVAIGRAIVR 151
Cdd:cd03260 80 RRRVGMVFQKPNPFP-GSIYDNVAYGLRLHGIkLKEELDERVEEALRKAALWDEVKDRLHAlgLSGGQQQRLCLARALAN 158
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 928002514 152 QPGVFLFDEPLSNLD--ATLrgqtRIE--IARLHKQFAkasVVYVTHDQIEAMTLADKIVLLHAGKDTErYGSIAQI 224
Cdd:cd03260 159 EPEVLLLDEPTSALDpiSTA----KIEelIAELKKEYT---IVIVTHNMQQAARVADRTAFLLNGRLVE-FGPTEQI 227
|
|
| CcmA |
COG1131 |
ABC-type multidrug transport system, ATPase component [Defense mechanisms]; |
4-233 |
7.85e-51 |
|
ABC-type multidrug transport system, ATPase component [Defense mechanisms];
Pssm-ID: 440746 [Multi-domain] Cd Length: 236 Bit Score: 170.24 E-value: 7.85e-51
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 4 ISLRGVQKAYGDgAPVIRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLSIGGK-IMNDVPAAQRGVAMVF 82
Cdd:COG1131 1 IEVRGLTKRYGD-KTALDGVSLTVEPGEIFGLLGPNGAGKTTTIRMLLGLLRPTSGEVRVLGEdVARDPAEVRRRIGYVP 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 83 QSYALFPHMTVFENMAFGLKLAKTPKEEIDRKVREAARVLQLEALLERRPKALSGGQRQRVAIGRAIVRQPGVFLFDEPL 162
Cdd:COG1131 80 QEPALYPDLTVRENLRFFARLYGLPRKEARERIDELLELFGLTDAADRKVGTLSGGMKQRLGLALALLHDPELLILDEPT 159
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 928002514 163 SNLDATLRGQTRIEIARLHKQfaKASVVYVTHDQIEAMTLADKIVLLHAGKdterygsIAQIGAPLELYHR 233
Cdd:COG1131 160 SGLDPEARRELWELLRELAAE--GKTVLLSTHYLEEAERLCDRVAIIDKGR-------IVADGTPDELKAR 221
|
|
| ABC_Org_Solvent_Resistant |
cd03261 |
ATP-binding cassette transport system involved in resistance to organic solvents; ABC ... |
4-213 |
2.23e-50 |
|
ATP-binding cassette transport system involved in resistance to organic solvents; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213228 [Multi-domain] Cd Length: 235 Bit Score: 168.83 E-value: 2.23e-50
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 4 ISLRGVQKAYGDgAPVIRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLSIGGKimnDVPAAQ-------- 75
Cdd:cd03261 1 IELRGLTKSFGG-RTVLKGVDLDVRRGEILAIIGPSGSGKSTLLRLIVGLLRPDSGEVLIDGE---DISGLSeaelyrlr 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 76 RGVAMVFQSYALFPHMTVFENMAFGLK-LAKTPKEEIDRKVREAARVLQLEALLERRPKALSGGQRQRVAIGRAIVRQPG 154
Cdd:cd03261 77 RRMGMLFQSGALFDSLTVFENVAFPLReHTRLSEEEIREIVLEKLEAVGLRGAEDLYPAELSGGMKKRVALARALALDPE 156
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 928002514 155 VFLFDEPLSNLDATLRGQTRIEIARLHKQFAKASVVyVTHDQIEAMTLADKIVLLHAGK 213
Cdd:cd03261 157 LLLYDEPTAGLDPIASGVIDDLIRSLKKELGLTSIM-VTHDLDTAFAIADRIAVLYDGK 214
|
|
| modC_ABC |
TIGR02142 |
molybdenum ABC transporter, ATP-binding protein; This model represents the ATP-binding ... |
22-358 |
2.17e-49 |
|
molybdenum ABC transporter, ATP-binding protein; This model represents the ATP-binding cassette (ABC) protein of the three subunit molybdate ABC transporter. The three proteins of this complex are homologous to proteins of the sulfate ABC transporter. Molybdenum may be used in nitrogenases of nitrogen-fixing bacteria and in molybdopterin cofactors. In some cases, molybdate may be transported by a sulfate transporter rather than by a specific molybdate transporter. [Transport and binding proteins, Anions]
Pssm-ID: 131197 [Multi-domain] Cd Length: 354 Bit Score: 169.91 E-value: 2.17e-49
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 22 DVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLSIGGKIMND------VPAAQRGVAMVFQSYALFPHMTVFE 95
Cdd:TIGR02142 15 DADFTLPGQGVTAIFGRSGSGKTTLIRLIAGLTRPDEGEIVLNGRTLFDsrkgifLPPEKRRIGYVFQEARLFPHLSVRG 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 96 NMAFGLKLAKTPkeeiDRKVREAA--RVLQLEALLERRPKALSGGQRQRVAIGRAIVRQPGVFLFDEPLSNLDATLRGQT 173
Cdd:TIGR02142 95 NLRYGMKRARPS----ERRISFERviELLGIGHLLGRLPGRLSGGEKQRVAIGRALLSSPRLLLMDEPLAALDDPRKYEI 170
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 174 RIEIARLHKQFaKASVVYVTHDQIEAMTLADKIVLLHAGKdterygsIAQIGAPLELYhrpksrfvagfiGSPRMNFLPG 253
Cdd:TIGR02142 171 LPYLERLHAEF-GIPILYVSHSLQEVLRLADRVVVLEDGR-------VAAAGPIAEVW------------ASPDLPWLAR 230
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 254 RVASVDAQGVIVTLDTTLENVRVPVDGAALEVAQP----------------VTLG-VRPEhlefiDTSSLQdeAVLTRTV 316
Cdd:TIGR02142 231 EDQGSLIEGVVAEHDQHYGLTALRLGGGHLWVPENlgptgarlrlrvpardVSLAlQKPE-----ATSIRN--ILPARVV 303
|
330 340 350 360
....*....|....*....|....*....|....*....|....*.
gi 928002514 317 SLVEQLGEHSYVHLDQpGGFTLIA----KAPGDTHLAPGDRAHLRV 358
Cdd:TIGR02142 304 EIEDSDIGRVGVVLES-GGKTLWAritrWARDELGIAPGTPVFAQI 348
|
|
| DppF |
COG1124 |
ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid ... |
4-217 |
7.56e-49 |
|
ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];
Pssm-ID: 440741 [Multi-domain] Cd Length: 248 Bit Score: 165.36 E-value: 7.56e-49
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 4 ISLRGVQKAYGDGA---PVIRDVDLEIGENE-FCVfLGPSGCGKSTLLCMIAGLEDLTDGDLSIGGKIMNDVP--AAQRG 77
Cdd:COG1124 2 LEVRNLSVSYGQGGrrvPVLKDVSLEVAPGEsFGL-VGESGSGKSTLLRALAGLERPWSGEVTFDGRPVTRRRrkAFRRR 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 78 VAMVFQSY--ALFPHMTVFENMAFGLKLAKTPkeEIDRKVREAARVLQL-EALLERRPKALSGGQRQRVAIGRAIVRQPG 154
Cdd:COG1124 81 VQMVFQDPyaSLHPRHTVDRILAEPLRIHGLP--DREERIAELLEQVGLpPSFLDRYPHQLSGGQRQRVAIARALILEPE 158
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 928002514 155 VFLFDEPLSNLDATLRGQTRIEIARLHKQFaKASVVYVTHDqIEAMT-LADKIVLLHAGKDTER 217
Cdd:COG1124 159 LLLLDEPTSALDVSVQAEILNLLKDLREER-GLTYLFVSHD-LAVVAhLCDRVAVMQNGRIVEE 220
|
|
| ABC_MetN_methionine_transporter |
cd03258 |
ATP-binding cassette domain of methionine transporter; MetN (also known as YusC) is an ... |
4-235 |
7.71e-49 |
|
ATP-binding cassette domain of methionine transporter; MetN (also known as YusC) is an ABC-type transporter encoded by metN of the metNPQ operon in Bacillus subtilis that is involved in methionine transport. Other members of this system include the MetP permease and the MetQ substrate binding protein. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213225 [Multi-domain] Cd Length: 233 Bit Score: 164.68 E-value: 7.71e-49
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 4 ISLRGVQKAYGDG---APVIRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLSIGGKIMNDVP-----AAQ 75
Cdd:cd03258 2 IELKNVSKVFGDTggkVTALKDVSLSVPKGEIFGIIGRSGAGKSTLIRCINGLERPTSGSVLVDGTDLTLLSgkelrKAR 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 76 RGVAMVFQSYALFPHMTVFENMAFGLKLAKTPKEEIDRKVREAARVLQLEALLERRPKALSGGQRQRVAIGRAIVRQPGV 155
Cdd:cd03258 82 RRIGMIFQHFNLLSSRTVFENVALPLEIAGVPKAEIEERVLELLELVGLEDKADAYPAQLSGGQKQRVGIARALANNPKV 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 156 FLFDEPLSNLDAtlrgQTRIEIARLHKQFAKA---SVVYVTHdQIEAM-TLADKIVLLHAGKdterygsIAQIGAPLELY 231
Cdd:cd03258 162 LLCDEATSALDP----ETTQSILALLRDINRElglTIVLITH-EMEVVkRICDRVAVMEKGE-------VVEEGTVEEVF 229
|
....
gi 928002514 232 HRPK 235
Cdd:cd03258 230 ANPQ 233
|
|
| FepC |
COG1120 |
ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component [Inorganic ion ... |
4-230 |
1.94e-48 |
|
ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component [Inorganic ion transport and metabolism, Coenzyme transport and metabolism];
Pssm-ID: 440737 [Multi-domain] Cd Length: 254 Bit Score: 164.45 E-value: 1.94e-48
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 4 ISLRGVQKAYGdGAPVIRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLSIGGKIMNDVPAAQRG--VAMV 81
Cdd:COG1120 2 LEAENLSVGYG-GRPVLDDVSLSLPPGEVTALLGPNGSGKSTLLRALAGLLKPSSGEVLLDGRDLASLSRRELArrIAYV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 82 FQSYALFPHMTVFENMAFG----LKLAKTPKEEIDRKVREAARVLQLEALLERRPKALSGGQRQRVAIGRAIVRQPGVFL 157
Cdd:COG1120 81 PQEPPAPFGLTVRELVALGryphLGLFGRPSAEDREAVEEALERTGLEHLADRPVDELSGGERQRVLIARALAQEPPLLL 160
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 928002514 158 FDEPLSNLDatLRGQtrIEIARLHKQFAKA---SVVYVTHDQIEAMTLADKIVLLHAGKdterygsIAQIGAPLEL 230
Cdd:COG1120 161 LDEPTSHLD--LAHQ--LEVLELLRRLARErgrTVVMVLHDLNLAARYADRLVLLKDGR-------IVAQGPPEEV 225
|
|
| glnQ |
PRK09493 |
glutamine ABC transporter ATP-binding protein GlnQ; |
4-236 |
3.38e-48 |
|
glutamine ABC transporter ATP-binding protein GlnQ;
Pssm-ID: 181906 [Multi-domain] Cd Length: 240 Bit Score: 163.34 E-value: 3.38e-48
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 4 ISLRGVQKAYGDgAPVIRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLSIGGKIMNDVPAAQRGV----A 79
Cdd:PRK09493 2 IEFKNVSKHFGP-TQVLHNIDLNIDQGEVVVIIGPSGSGKSTLLRCINKLEEITSGDLIVDGLKVNDPKVDERLIrqeaG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 80 MVFQSYALFPHMTVFENMAFG-LKLAKTPKEEIDRKVREAARVLQLEALLERRPKALSGGQRQRVAIGRAIVRQPGVFLF 158
Cdd:PRK09493 81 MVFQQFYLFPHLTALENVMFGpLRVRGASKEEAEKQARELLAKVGLAERAHHYPSELSGGQQQRVAIARALAVKPKLMLF 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 159 DEPLSNLDATLRGqtriEIARLHKQFAKA--SVVYVTHDQIEAMTLADKIVLLHAGKdterygsIAQIGAPLELYHRPKS 236
Cdd:PRK09493 161 DEPTSALDPELRH----EVLKVMQDLAEEgmTMVIVTHEIGFAEKVASRLIFIDKGR-------IAEDGDPQVLIKNPPS 229
|
|
| FetA |
COG4619 |
ABC-type iron transporter FetAB, ATPase component [Inorganic ion transport and metabolism]; |
4-213 |
5.93e-48 |
|
ABC-type iron transporter FetAB, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 443661 [Multi-domain] Cd Length: 209 Bit Score: 161.91 E-value: 5.93e-48
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 4 ISLRGVQKAYgDGAPVIRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLSIGGKIMNDVPAAQ--RGVAMV 81
Cdd:COG4619 1 LELEGLSFRV-GGKPILSPVSLTLEAGECVAITGPSGSGKSTLLRALADLDPPTSGEIYLDGKPLSAMPPPEwrRQVAYV 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 82 FQSYALFPhMTVFENMAFGLKLAktpKEEIDR-KVREAARVLQL-EALLERRPKALSGGQRQRVAIGRAIVRQPGVFLFD 159
Cdd:COG4619 80 PQEPALWG-GTVRDNLPFPFQLR---ERKFDReRALELLERLGLpPDILDKPVERLSGGERQRLALIRALLLQPDVLLLD 155
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 928002514 160 EPLSNLDATLRGqtRIE--IARLHKQfAKASVVYVTHDQIEAMTLADKIVLLHAGK 213
Cdd:COG4619 156 EPTSALDPENTR--RVEelLREYLAE-EGRAVLWVSHDPEQIERVADRVLTLEAGR 208
|
|
| GsiA |
COG1123 |
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain ... |
4-233 |
7.07e-48 |
|
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 440740 [Multi-domain] Cd Length: 514 Bit Score: 169.70 E-value: 7.07e-48
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 4 ISLRGVQKAYGDGAP----VIRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLSIGGKIMNDVPAAQ---- 75
Cdd:COG1123 261 LEVRNLSKRYPVRGKggvrAVDDVSLTLRRGETLGLVGESGSGKSTLARLLLGLLRPTSGSILFDGKDLTKLSRRSlrel 340
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 76 -RGVAMVFQ--SYALFPHMTVFENMAFGLKLAKT-PKEEIDRKVREAARVLQL-EALLERRPKALSGGQRQRVAIGRAIV 150
Cdd:COG1123 341 rRRVQMVFQdpYSSLNPRMTVGDIIAEPLRLHGLlSRAERRERVAELLERVGLpPDLADRYPHELSGGQRQRVAIARALA 420
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 151 RQPGVFLFDEPLSNLDATLRGQTRIEIARLHKQFAKaSVVYVTHDqIEAM-TLADKIVLLHAGKDTERyGSIAQI-GAPL 228
Cdd:COG1123 421 LEPKLLILDEPTSALDVSVQAQILNLLRDLQRELGL-TYLFISHD-LAVVrYIADRVAVMYDGRIVED-GPTEEVfANPQ 497
|
....*
gi 928002514 229 ELYHR 233
Cdd:COG1123 498 HPYTR 502
|
|
| AbcC |
COG1135 |
ABC-type methionine transport system, ATPase component [Amino acid transport and metabolism]; |
4-278 |
1.22e-47 |
|
ABC-type methionine transport system, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 440750 [Multi-domain] Cd Length: 339 Bit Score: 164.87 E-value: 1.22e-47
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 4 ISLRGVQKAY-GDGAPVI--RDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLSIGGKIMNDVP-----AAQ 75
Cdd:COG1135 2 IELENLSKTFpTKGGPVTalDDVSLTIEKGEIFGIIGYSGAGKSTLIRCINLLERPTSGSVLVDGVDLTALSerelrAAR 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 76 RGVAMVFQSYALFPHMTVFENMAFGLKLAKTPKEEIDRKVREAARVLQLEALLERRPKALSGGQRQRVAIGRAIVRQPGV 155
Cdd:COG1135 82 RKIGMIFQHFNLLSSRTVAENVALPLEIAGVPKAEIRKRVAELLELVGLSDKADAYPSQLSGGQKQRVGIARALANNPKV 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 156 FLFDEPLSNLDAtlrgQTRIEI----ARLHKQFaKASVVYVTHDqieaM----TLADKIVLLHAGKdterygsIAQIGAP 227
Cdd:COG1135 162 LLCDEATSALDP----ETTRSIldllKDINREL-GLTIVLITHE----MdvvrRICDRVAVLENGR-------IVEQGPV 225
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*
gi 928002514 228 LELYHRPKSRFVAGFIGSPRMNFLPG----RVASVDAQGVIVTLDTTLENVRVPV 278
Cdd:COG1135 226 LDVFANPQSELTRRFLPTVLNDELPEellaRLREAAGGGRLVRLTFVGESADEPL 280
|
|
| GsiA |
COG1123 |
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain ... |
4-293 |
1.37e-47 |
|
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 440740 [Multi-domain] Cd Length: 514 Bit Score: 168.93 E-value: 1.37e-47
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 4 ISLRGVQKAYGDGA-PVIRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLT---DGDLSIGGKIMNDVPAAQRG-- 77
Cdd:COG1123 5 LEVRDLSVRYPGGDvPAVDGVSLTIAPGETVALVGESGSGKSTLALALMGLLPHGgriSGEVLLDGRDLLELSEALRGrr 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 78 VAMVFQS--YALFPhMTVFENMAFGLKLAKTPKEEIDRKVREAARVLQLEALLERRPKALSGGQRQRVAIGRAIVRQPGV 155
Cdd:COG1123 85 IGMVFQDpmTQLNP-VTVGDQIAEALENLGLSRAEARARVLELLEAVGLERRLDRYPHQLSGGQRQRVAIAMALALDPDL 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 156 FLFDEPLSNLDATLRGQTRIEIARLHKQFAKAsVVYVTHDQIEAMTLADKIVLLHAGKdterygsIAQIGAPLELYHRPK 235
Cdd:COG1123 164 LIADEPTTALDVTTQAEILDLLRELQRERGTT-VLLITHDLGVVAEIADRVVVMDDGR-------IVEDGPPEEILAAPQ 235
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 928002514 236 SRFVAGFIGSPRMNFLPGRVAS---VDAQGVIVTLDTTLENVRVPVDGAALEVAQPVTLGV 293
Cdd:COG1123 236 ALAAVPRLGAARGRAAPAAAAAeplLEVRNLSKRYPVRGKGGVRAVDDVSLTLRRGETLGL 296
|
|
| NatA |
COG4555 |
ABC-type Na+ transport system, ATPase component NatA [Energy production and conversion, ... |
4-224 |
4.00e-47 |
|
ABC-type Na+ transport system, ATPase component NatA [Energy production and conversion, Inorganic ion transport and metabolism];
Pssm-ID: 443618 [Multi-domain] Cd Length: 243 Bit Score: 160.79 E-value: 4.00e-47
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 4 ISLRGVQKAYGDGaPVIRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLSIGGK-IMNDVPAAQRGVAMVF 82
Cdd:COG4555 2 IEVENLSKKYGKV-PALKDVSFTAKDGEITGLLGPNGAGKTTLLRMLAGLLKPDSGSILIDGEdVRKEPREARRQIGVLP 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 83 QSYALFPHMTVFENMAFGLKLAKTPKEEIDRKVREAARVLQLEALLERRPKALSGGQRQRVAIGRAIVRQPGVFLFDEPL 162
Cdd:COG4555 81 DERGLYDRLTVRENIRYFAELYGLFDEELKKRIEELIELLGLEEFLDRRVGELSTGMKKKVALARALVHDPKVLLLDEPT 160
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 928002514 163 SNLDATLRGQTRIEIARLHKQfaKASVVYVTHDQIEAMTLADKIVLLHAGKdTERYGSIAQI 224
Cdd:COG4555 161 NGLDVMARRLLREILRALKKE--GKTVLFSSHIMQEVEALCDRVVILHKGK-VVAQGSLDEL 219
|
|
| PhnC |
COG3638 |
ABC-type phosphate/phosphonate transport system, ATPase component [Inorganic ion transport and ... |
4-213 |
5.22e-47 |
|
ABC-type phosphate/phosphonate transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 442855 [Multi-domain] Cd Length: 249 Bit Score: 160.61 E-value: 5.22e-47
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 4 ISLRGVQKAYGDGAPVIRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLSIGGKIMN-----DVPAAQRGV 78
Cdd:COG3638 3 LELRNLSKRYPGGTPALDDVSLEIERGEFVALIGPSGAGKSTLLRCLNGLVEPTSGEILVDGQDVTalrgrALRRLRRRI 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 79 AMVFQSYALFPHMTVFENMAFGLkLAKT----------PKEEIDRkvreAARVLQ---LEALLERRPKALSGGQRQRVAI 145
Cdd:COG3638 83 GMIFQQFNLVPRLSVLTNVLAGR-LGRTstwrsllglfPPEDRER----ALEALErvgLADKAYQRADQLSGGQQQRVAI 157
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 928002514 146 GRAIVRQPGVFLFDEPLSNLD--------ATLRgqtriEIARLHkqfaKASVVYVTHdQIE-AMTLADKIVLLHAGK 213
Cdd:COG3638 158 ARALVQEPKLILADEPVASLDpktarqvmDLLR-----RIARED----GITVVVNLH-QVDlARRYADRIIGLRDGR 224
|
|
| FtsE |
TIGR02673 |
cell division ATP-binding protein FtsE; This model describes FtsE, a member of the ABC ... |
4-213 |
1.14e-46 |
|
cell division ATP-binding protein FtsE; This model describes FtsE, a member of the ABC transporter ATP-binding protein family. This protein, and its permease partner FtsX, localize to the division site. In a number of species, the ftsEX gene pair is located next to FtsY, the signal recognition particle-docking protein. [Cellular processes, Cell division]
Pssm-ID: 131721 [Multi-domain] Cd Length: 214 Bit Score: 158.57 E-value: 1.14e-46
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 4 ISLRGVQKAYGDGAPVIRDVDLEIGENEFcVFL-GPSGCGKSTLLCMIAGLEDLTDGDLSIGGKIMN-----DVPAAQRG 77
Cdd:TIGR02673 2 IEFHNVSKAYPGGVAALHDVSLHIRKGEF-LFLtGPSGAGKTTLLKLLYGALTPSRGQVRIAGEDVNrlrgrQLPLLRRR 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 78 VAMVFQSYALFPHMTVFENMAFGLKLAKTPKEEIDRKVREAARVLQLEALLERRPKALSGGQRQRVAIGRAIVRQPGVFL 157
Cdd:TIGR02673 81 IGVVFQDFRLLPDRTVYENVALPLEVRGKKEREIQRRVGAALRQVGLEHKADAFPEQLSGGEQQRVAIARAIVNSPPLLL 160
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 928002514 158 FDEPLSNLDATLRGQtrieIARLHKQFAK--ASVVYVTHDQIEAMTLADKIVLLHAGK 213
Cdd:TIGR02673 161 ADEPTGNLDPDLSER----ILDLLKRLNKrgTTVIVATHDLSLVDRVAHRVIILDDGR 214
|
|
| ABC_NikE_OppD_transporters |
cd03257 |
ATP-binding cassette domain of nickel/oligopeptides specific transporters; The ABC transporter ... |
4-213 |
2.72e-46 |
|
ATP-binding cassette domain of nickel/oligopeptides specific transporters; The ABC transporter subfamily specific for the transport of dipeptides, oligopeptides (OppD), and nickel (NikDE). The NikABCDE system of E. coli belongs to this family and is composed of the periplasmic binding protein NikA, two integral membrane components (NikB and NikC), and two ATPase (NikD and NikE). The NikABCDE transporter is synthesized under anaerobic conditions to meet the increased demand for nickel resulting from hydrogenase synthesis. The molecular mechanism of nickel uptake in many bacteria and most archaea is not known. Many other members of this ABC family are also involved in the uptake of dipeptides and oligopeptides. The oligopeptide transport system (Opp) is a five-component ABC transport composed of a membrane-anchored substrate binding proteins (SRP), OppA, two transmembrane proteins, OppB and OppC, and two ATP-binding domains, OppD and OppF.
Pssm-ID: 213224 [Multi-domain] Cd Length: 228 Bit Score: 158.05 E-value: 2.72e-46
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 4 ISLRGVQKAYGDGA---PVIRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLSIGGKIMNDVPAAQRG--- 77
Cdd:cd03257 2 LEVKNLSVSFPTGGgsvKALDDVSFSIKKGETLGLVGESGSGKSTLARAILGLLKPTSGSIIFDGKDLLKLSRRLRKirr 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 78 --VAMVFQSY--ALFPHMTVFENMAFGLKLAK--TPKEEIDRKVREAARVLQL-EALLERRPKALSGGQRQRVAIGRAIV 150
Cdd:cd03257 82 keIQMVFQDPmsSLNPRMTIGEQIAEPLRIHGklSKKEARKEAVLLLLVGVGLpEEVLNRYPHELSGGQRQRVAIARALA 161
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 928002514 151 RQPGVFLFDEPLSNLDATLRGQTRIEIARLHKQFaKASVVYVTHDqIEAM-TLADKIVLLHAGK 213
Cdd:cd03257 162 LNPKLLIADEPTSALDVSVQAQILDLLKKLQEEL-GLTLLFITHD-LGVVaKIADRVAVMYAGK 223
|
|
| ntrCD |
TIGR01184 |
nitrate transport ATP-binding subunits C and D; This model describes the ATP binding subunits ... |
20-237 |
3.74e-46 |
|
nitrate transport ATP-binding subunits C and D; This model describes the ATP binding subunits of nitrate transport in bacteria and archaea. This protein belongs to the ATP-binding cassette (ABC) superfamily. It is thought that the two subunits encoded by ntrC and ntrD form the binding surface for interaction with ATP. This model is restricted in identifying ATP binding subunit associated with the nitrate transport. Nitrate assimilation is aided by other proteins derived from the operon which among others include products of ntrA - a regulatory protein; ntrB - a hydropbobic transmembrane permease and narB - a reductase. [Transport and binding proteins, Anions, Transport and binding proteins, Other]
Pssm-ID: 130252 [Multi-domain] Cd Length: 230 Bit Score: 158.01 E-value: 3.74e-46
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 20 IRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLSIGGKIMNDvPAAQRGVamVFQSYALFPHMTVFENMAF 99
Cdd:TIGR01184 1 LKGVNLTIQQGEFISLIGHSGCGKSTLLNLISGLAQPTSGGVILEGKQITE-PGPDRMV--VFQNYSLLPWLTVRENIAL 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 100 GLK--LAKTPKEEIDRKVREAARVLQLEALLERRPKALSGGQRQRVAIGRAIVRQPGVFLFDEPLSNLDATLRGQTRIEI 177
Cdd:TIGR01184 78 AVDrvLPDLSKSERRAIVEEHIALVGLTEAADKRPGQLSGGMKQRVAIARALSIRPKVLLLDEPFGALDALTRGNLQEEL 157
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 928002514 178 ARLHKQfAKASVVYVTHDQIEAMTLADKIVLLHAGKDterygsiAQIGAPLEL-YHRPKSR 237
Cdd:TIGR01184 158 MQIWEE-HRVTVLMVTHDVDEALLLSDRVVMLTNGPA-------ANIGQILEVpFPRPRDR 210
|
|
| tauB |
PRK11248 |
taurine ABC transporter ATP-binding subunit; |
15-212 |
7.30e-45 |
|
taurine ABC transporter ATP-binding subunit;
Pssm-ID: 183056 [Multi-domain] Cd Length: 255 Bit Score: 155.24 E-value: 7.30e-45
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 15 DGAPVIRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLSIGGKIMNDvPAAQRGVamVFQSYALFPHMTVF 94
Cdd:PRK11248 12 GGKPALEDINLTLESGELLVVLGPSGCGKTTLLNLIAGFVPYQHGSITLDGKPVEG-PGAERGV--VFQNEGLLPWRNVQ 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 95 ENMAFGLKLAKTPKEEIDRKVREAARVLQLEALLERRPKALSGGQRQRVAIGRAIVRQPGVFLFDEPLSNLDATLRGQTR 174
Cdd:PRK11248 89 DNVAFGLQLAGVEKMQRLEIAHQMLKKVGLEGAEKRYIWQLSGGQRQRVGIARALAANPQLLLLDEPFGALDAFTREQMQ 168
|
170 180 190
....*....|....*....|....*....|....*...
gi 928002514 175 IEIARLHKQFAKaSVVYVTHDQIEAMTLADKIVLLHAG 212
Cdd:PRK11248 169 TLLLKLWQETGK-QVLLITHDIEEAVFMATELVLLSPG 205
|
|
| ABC_ThiQ_thiamine_transporter |
cd03298 |
ATP-binding cassette domain of the thiamine transport system; Part of the ... |
22-213 |
5.31e-44 |
|
ATP-binding cassette domain of the thiamine transport system; Part of the binding-protein-dependent transport system tbpA-thiPQ for thiamine and TPP. Probably responsible for the translocation of thiamine across the membrane. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213265 [Multi-domain] Cd Length: 211 Bit Score: 151.49 E-value: 5.31e-44
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 22 DVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLSIGGKIMNDVPAAQRGVAMVFQSYALFPHMTVFENMAFGL 101
Cdd:cd03298 16 HFDLTFAQGEITAIVGPSGSGKSTLLNLIAGFETPQSGRVLINGVDVTAAPPADRPVSMLFQENNLFAHLTVEQNVGLGL 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 102 KLAKTPKEEIDRKVREAARVLQLEALLERRPKALSGGQRQRVAIGRAIVRQPGVFLFDEPLSNLDATLRGQTRIEIARLH 181
Cdd:cd03298 96 SPGLKLTAEDRQAIEVALARVGLAGLEKRLPGELSGGERQRVALARVLVRDKPVLLLDEPFAALDPALRAEMLDLVLDLH 175
|
170 180 190
....*....|....*....|....*....|..
gi 928002514 182 KQfAKASVVYVTHDQIEAMTLADKIVLLHAGK 213
Cdd:cd03298 176 AE-TKMTVLMVTHQPEDAKRLAQRVVFLDNGR 206
|
|
| PstB |
COG1117 |
ABC-type phosphate transport system, ATPase component [Inorganic ion transport and metabolism]; ... |
2-224 |
5.82e-43 |
|
ABC-type phosphate transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 440734 [Multi-domain] Cd Length: 258 Bit Score: 150.19 E-value: 5.82e-43
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 2 ASISLRGVQKAYGDgAPVIRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGdLSIGGKIM----N------DV 71
Cdd:COG1117 10 PKIEVRNLNVYYGD-KQALKDINLDIPENKVTALIGPSGCGKSTLLRCLNRMNDLIPG-ARVEGEILldgeDiydpdvDV 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 72 PAAQRGVAMVFQSYALFPhMTVFENMAFGLKLA-KTPKEEIDRKVREAarvLQLEAL-------LERRPKALSGGQRQRV 143
Cdd:COG1117 88 VELRRRVGMVFQKPNPFP-KSIYDNVAYGLRLHgIKSKSELDEIVEES---LRKAALwdevkdrLKKSALGLSGGQQQRL 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 144 AIGRAIVRQPGVFLFDEPLSNLD--ATLrgqtRIE--IARLHKQFakaSVVYVTHDQIEAMTLADKIVLLHAGKDTErYG 219
Cdd:COG1117 164 CIARALAVEPEVLLMDEPTSALDpiSTA----KIEelILELKKDY---TIVIVTHNMQQAARVSDYTAFFYLGELVE-FG 235
|
....*
gi 928002514 220 SIAQI 224
Cdd:COG1117 236 PTEQI 240
|
|
| SunT |
COG2274 |
ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase ... |
3-230 |
7.13e-43 |
|
ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain [Defense mechanisms];
Pssm-ID: 441875 [Multi-domain] Cd Length: 711 Bit Score: 158.84 E-value: 7.13e-43
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 3 SISLRGVQKAY-GDGAPVIRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLSIGGKIMNDVPAAQ--RGVA 79
Cdd:COG2274 473 DIELENVSFRYpGDSPPVLDNISLTIKPGERVAIVGRSGSGKSTLLKLLLGLYEPTSGRILIDGIDLRQIDPASlrRQIG 552
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 80 MVFQSYALFpHMTVFENMAFGLKLAktPKEEIdrkvREAARVLQLEALLERRPK-----------ALSGGQRQRVAIGRA 148
Cdd:COG2274 553 VVLQDVFLF-SGTIRENITLGDPDA--TDEEI----IEAARLAGLHDFIEALPMgydtvvgeggsNLSGGQRQRLAIARA 625
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 149 IVRQPGVFLFDEPLSNLDAtlRGQTRIeIARLHKQFAKASVVYVTHDqIEAMTLADKIVLLHAGKdterygsIAQIGAPL 228
Cdd:COG2274 626 LLRNPRILILDEATSALDA--ETEAII-LENLRRLLKGRTVIIIAHR-LSTIRLADRIIVLDKGR-------IVEDGTHE 694
|
..
gi 928002514 229 EL 230
Cdd:COG2274 695 EL 696
|
|
| ABC_PhnC_transporter |
cd03256 |
ATP-binding cassette domain of the binding protein-dependent phosphonate transport system; ... |
4-213 |
1.05e-42 |
|
ATP-binding cassette domain of the binding protein-dependent phosphonate transport system; Phosphonates are a class of organophosphorus compounds characterized by a chemically stable carbon-to-phosphorus (C-P) bond. Phosphonates are widespread among naturally occurring compounds in all kingdoms of wildlife, but only prokaryotic microorganisms are able to cleave this bond. Certain bacteria such as E. coli can use alkylphosphonates as a phosphorus source. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213223 [Multi-domain] Cd Length: 241 Bit Score: 149.26 E-value: 1.05e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 4 ISLRGVQKAYGDGAPVIRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLSIGGKIMNDVP-----AAQRGV 78
Cdd:cd03256 1 IEVENLSKTYPNGKKALKDVSLSINPGEFVALIGPSGAGKSTLLRCLNGLVEPTSGSVLIDGTDINKLKgkalrQLRRQI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 79 AMVFQSYALFPHMTVFENMAFGlKLAKT----------PKEEIdRKVREAARVLQLEALLERRPKALSGGQRQRVAIGRA 148
Cdd:cd03256 81 GMIFQQFNLIERLSVLENVLSG-RLGRRstwrslfglfPKEEK-QRALAALERVGLLDKAYQRADQLSGGQQQRVAIARA 158
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 928002514 149 IVRQPGVFLFDEPLSNLDATLRGQTRIEIARLHKQFAKAsVVYVTHdQIE-AMTLADKIVLLHAGK 213
Cdd:cd03256 159 LMQQPKLILADEPVASLDPASSRQVMDLLKRINREEGIT-VIVSLH-QVDlAREYADRIVGLKDGR 222
|
|
| ABC_FtsE |
cd03292 |
Cell division ATP-binding protein FtsE; The FtsEX complex resembles an ABC transporter, where ... |
4-195 |
1.21e-42 |
|
Cell division ATP-binding protein FtsE; The FtsEX complex resembles an ABC transporter, where FtsE is the ATPase and the membrane subunit FtsX resembles a permease subunit. But rather than transporting any substrate, the complex acts in cell division by undergoing conformational changes that alter the activity of cell wall hydrolases located outside the plasma membrane. The complex is widely conserved in bacteria, but also extremely divergent in sequence between different lineages
Pssm-ID: 213259 [Multi-domain] Cd Length: 214 Bit Score: 147.94 E-value: 1.21e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 4 ISLRGVQKAYGDGAPVIRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLSIGGKIMND-----VPAAQRGV 78
Cdd:cd03292 1 IEFINVTKTYPNGTAALDGINISISAGEFVFLVGPSGAGKSTLLKLIYKEELPTSGTIRVNGQDVSDlrgraIPYLRRKI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 79 AMVFQSYALFPHMTVFENMAFGLKLAKTPKEEIDRKVREAARVLQLEALLERRPKALSGGQRQRVAIGRAIVRQPGVFLF 158
Cdd:cd03292 81 GVVFQDFRLLPDRNVYENVAFALEVTGVPPREIRKRVPAALELVGLSHKHRALPAELSGGEQQRVAIARAIVNSPTILIA 160
|
170 180 190
....*....|....*....|....*....|....*....
gi 928002514 159 DEPLSNLDATlrgqTRIEIARLHKQFAKA--SVVYVTHD 195
Cdd:cd03292 161 DEPTGNLDPD----TTWEIMNLLKKINKAgtTVVVATHA 195
|
|
| ABC_subfamily_A |
cd03263 |
ATP-binding cassette domain of the lipid transporters, subfamily A; The ABCA subfamily ... |
4-230 |
1.36e-42 |
|
ATP-binding cassette domain of the lipid transporters, subfamily A; The ABCA subfamily mediates the transport of a variety of lipid compounds. Mutations of members of ABCA subfamily are associated with human genetic diseases, such as, familial high-density lipoprotein (HDL) deficiency, neonatal surfactant deficiency, degenerative retinopathies, and congenital keratinization disorders. The ABCA1 protein is involved in disorders of cholesterol transport and high-density lipoprotein (HDL) biosynthesis. The ABCA4 (ABCR) protein transports vitamin A derivatives in the outer segments of photoreceptor cells, and therefore, performs a crucial step in the visual cycle. The ABCA genes are not present in yeast. However, evolutionary studies of ABCA genes indicate that they arose as transporters that subsequently duplicated and that certain sets of ABCA genes were lost in different eukaryotic lineages.
Pssm-ID: 213230 [Multi-domain] Cd Length: 220 Bit Score: 148.04 E-value: 1.36e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 4 ISLRGVQKAYGDGA-PVIRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLSIGGK-IMNDVPAAQRGVAMV 81
Cdd:cd03263 1 LQIRNLTKTYKKGTkPAVDDLSLNVYKGEIFGLLGHNGAGKTTTLKMLTGELRPTSGTAYINGYsIRTDRKAARQSLGYC 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 82 FQSYALFPHMTVFENMAFGLKLAKTPKEEIDRKVREAARVLQLEALLERRPKALSGGQRQRVAIGRAIVRQPGVFLFDEP 161
Cdd:cd03263 81 PQFDALFDELTVREHLRFYARLKGLPKSEIKEEVELLLRVLGLTDKANKRARTLSGGMKRKLSLAIALIGGPSVLLLDEP 160
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 928002514 162 LSNLDATLRgqtRIEIARLHKQFAKASVVYVTHDQIEAMTLADKIVLLHAGKdterygsIAQIGAPLEL 230
Cdd:cd03263 161 TSGLDPASR---RAIWDLILEVRKGRSIILTTHSMDEAEALCDRIAIMSDGK-------LRCIGSPQEL 219
|
|
| ssuB |
PRK11247 |
aliphatic sulfonates transport ATP-binding subunit; Provisional |
4-255 |
9.00e-42 |
|
aliphatic sulfonates transport ATP-binding subunit; Provisional
Pssm-ID: 183055 [Multi-domain] Cd Length: 257 Bit Score: 147.13 E-value: 9.00e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 4 ISLRGVQKAYGDGApVIRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLSIGGKIMNDvpaAQRGVAMVFQ 83
Cdd:PRK11247 13 LLLNAVSKRYGERT-VLNQLDLHIPAGQFVAVVGRSGCGKSTLLRLLAGLETPSAGELLAGTAPLAE---AREDTRLMFQ 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 84 SYALFPHMTVFENMAFGLKlaktpkeeidRKVREAArvlqLEAL----LERR----PKALSGGQRQRVAIGRAIVRQPGV 155
Cdd:PRK11247 89 DARLLPWKKVIDNVGLGLK----------GQWRDAA----LQALaavgLADRanewPAALSGGQKQRVALARALIHRPGL 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 156 FLFDEPLSNLDATlrgqTRIE----IARLHKQFAkASVVYVTHDQIEAMTLADKIVLLHAGkdterygsiaQIGAPLEL- 230
Cdd:PRK11247 155 LLLDEPLGALDAL----TRIEmqdlIESLWQQHG-FTVLLVTHDVSEAVAMADRVLLIEEG----------KIGLDLTVd 219
|
250 260
....*....|....*....|....*
gi 928002514 231 YHRPKSRfvagfiGSPRMNFLPGRV 255
Cdd:PRK11247 220 LPRPRRR------GSARLAELEAEV 238
|
|
| ECF_ATPase_1 |
TIGR04520 |
energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette ... |
4-233 |
1.64e-41 |
|
energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette (ABC) proteins by homology, but belong to energy coupling factor (ECF) transport systems. The architecture in general is two ATPase subunits (or a double-length fusion protein), a T component, and a substrate capture (S) component that is highly variable, and may be interchangeable in genomes with only one T component. This model identifies many but not examples of the upstream member of the pair of ECF ATPases in Firmicutes and Mollicutes. [Transport and binding proteins, Unknown substrate]
Pssm-ID: 275313 [Multi-domain] Cd Length: 268 Bit Score: 146.81 E-value: 1.64e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 4 ISLRGVQKAYGDGA-PVIRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLSIGG-KIMND--VPAAQRGVA 79
Cdd:TIGR04520 1 IEVENVSFSYPESEkPALKNVSLSIEKGEFVAIIGHNGSGKSTLAKLLNGLLLPTSGKVTVDGlDTLDEenLWEIRKKVG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 80 MVFQSyalfPH-----MTVFENMAFGLKLAKTPKEEIDRKVREAARVLQLEALLERRPKALSGGQRQRVAIGRAIVRQPG 154
Cdd:TIGR04520 81 MVFQN----PDnqfvgATVEDDVAFGLENLGVPREEMRKRVDEALKLVGMEDFRDREPHLLSGGQKQRVAIAGVLAMRPD 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 155 VFLFDEPLSNLDAtlRGQTRI--EIARLHKQFAKaSVVYVTHDqIEAMTLADKIVLLHAGKdterygsIAQIGAPLELYH 232
Cdd:TIGR04520 157 IIILDEATSMLDP--KGRKEVleTIRKLNKEEGI-TVISITHD-MEEAVLADRVIVMNKGK-------IVAEGTPREIFS 225
|
.
gi 928002514 233 R 233
Cdd:TIGR04520 226 Q 226
|
|
| YnjD |
COG4136 |
ABC-type uncharacterized transport system YnjBCD, ATPase component [General function ... |
3-195 |
3.47e-41 |
|
ABC-type uncharacterized transport system YnjBCD, ATPase component [General function prediction only];
Pssm-ID: 443311 [Multi-domain] Cd Length: 211 Bit Score: 144.16 E-value: 3.47e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 3 SISLRGVQKAYGdGAPVIRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDL---TDGDLSIGGKIMNDVPAAQRGVA 79
Cdd:COG4136 1 MLSLENLTITLG-GRPLLAPLSLTVAPGEILTLMGPSGSGKSTLLAAIAGTLSPafsASGEVLLNGRRLTALPAEQRRIG 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 80 MVFQSYALFPHMTVFENMAFGLKlAKTPKEEIDRKVREAARVLQLEALLERRPKALSGGQRQRVAIGRAIVRQPGVFLFD 159
Cdd:COG4136 80 ILFQDDLLFPHLSVGENLAFALP-PTIGRAQRRARVEQALEEAGLAGFADRDPATLSGGQRARVALLRALLAEPRALLLD 158
|
170 180 190
....*....|....*....|....*....|....*.
gi 928002514 160 EPLSNLDATLRGQTRiEIARLHKQFAKASVVYVTHD 195
Cdd:COG4136 159 EPFSKLDAALRAQFR-EFVFEQIRQRGIPALLVTHD 193
|
|
| ABC_DR_subfamily_A |
cd03230 |
ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily ... |
4-213 |
3.81e-41 |
|
ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; This family of ATP-binding proteins belongs to a multi-subunit transporter involved in drug resistance (BcrA and DrrA), nodulation, lipid transport, and lantibiotic immunity. In bacteria and archaea, these transporters usually include an ATP-binding protein and one or two integral membrane proteins. Eukaryotic systems of the ABCA subfamily display ABC domains that are quite similar to this family. The ATP-binding domain shows the highest similarity between all members of the ABC transporter family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213197 [Multi-domain] Cd Length: 173 Bit Score: 142.92 E-value: 3.81e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 4 ISLRGVQKAYGDGaPVIRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLSIGGKIMNDVPAAQRG-VAMVF 82
Cdd:cd03230 1 IEVRNLSKRYGKK-TALDDISLTVEKGEIYGLLGPNGAGKTTLIKIILGLLKPDSGEIKVLGKDIKKEPEEVKRrIGYLP 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 83 QSYALFPHMTVFENMAfglklaktpkeeidrkvreaarvlqleallerrpkaLSGGQRQRVAIGRAIVRQPGVFLFDEPL 162
Cdd:cd03230 80 EEPSLYENLTVRENLK------------------------------------LSGGMKQRLALAQALLHDPELLILDEPT 123
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 928002514 163 SNLDAtlrgQTRIEIARLHKQFAK--ASVVYVTHDQIEAMTLADKIVLLHAGK 213
Cdd:cd03230 124 SGLDP----ESRREFWELLRELKKegKTILLSSHILEEAERLCDRVAILNNGR 172
|
|
| ArtP |
COG4161 |
ABC-type arginine transport system, ATPase component [Amino acid transport and metabolism]; |
3-227 |
4.76e-41 |
|
ABC-type arginine transport system, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 443326 [Multi-domain] Cd Length: 242 Bit Score: 144.77 E-value: 4.76e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 3 SISLRGVQKAYGdGAPVIRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLSIGGKIMN--------DVPAA 74
Cdd:COG4161 2 SIQLKNINCFYG-SHQALFDINLECPSGETLVLLGPSGAGKSSLLRVLNLLETPDSGQLNIAGHQFDfsqkpsekAIRLL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 75 QRGVAMVFQSYALFPHMTVFENM-AFGLKLAKTPKEEIDRKVREAARVLQLEALLERRPKALSGGQRQRVAIGRAIVRQP 153
Cdd:COG4161 81 RQKVGMVFQQYNLWPHLTVMENLiEAPCKVLGLSKEQAREKAMKLLARLRLTDKADRFPLHLSGGQQQRVAIARALMMEP 160
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 928002514 154 GVFLFDEPLSNLDATLRGQtrieIARLHKQFAKASV--VYVTHDQIEAMTLADKIVLLHAGKDTErYGSIAQIGAP 227
Cdd:COG4161 161 QVLLFDEPTAALDPEITAQ----VVEIIRELSQTGItqVIVTHEVEFARKVASQVVYMEKGRIIE-QGDASHFTQP 231
|
|
| ZnuC |
COG1121 |
ABC-type Mn2+/Zn2+ transport system, ATPase component [Inorganic ion transport and metabolism]; ... |
1-209 |
5.76e-41 |
|
ABC-type Mn2+/Zn2+ transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 440738 [Multi-domain] Cd Length: 245 Bit Score: 144.46 E-value: 5.76e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 1 MASISLRGVQKAYGdGAPVIRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLSIGGKimnDVPAAQRGVAM 80
Cdd:COG1121 4 MPAIELENLTVSYG-GRPVLEDVSLTIPPGEFVAIVGPNGAGKSTLLKAILGLLPPTSGTVRLFGK---PPRRARRRIGY 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 81 VFQSYAL---FPhMTVFENMAFGL----KLAKTPKEEIDRKVREAARVLQLEALLERRPKALSGGQRQRVAIGRAIVRQP 153
Cdd:COG1121 80 VPQRAEVdwdFP-ITVRDVVLMGRygrrGLFRRPSRADREAVDEALERVGLEDLADRPIGELSGGQQQRVLLARALAQDP 158
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 928002514 154 GVFLFDEPLSNLDAtlrgQTRIEIARLHKQFAKA--SVVYVTHDQIEAMTLADKIVLL 209
Cdd:COG1121 159 DLLLLDEPFAGVDA----ATEEALYELLRELRREgkTILVVTHDLGAVREYFDRVLLL 212
|
|
| thiQ |
PRK10771 |
thiamine ABC transporter ATP-binding protein ThiQ; |
24-213 |
2.00e-40 |
|
thiamine ABC transporter ATP-binding protein ThiQ;
Pssm-ID: 182716 [Multi-domain] Cd Length: 232 Bit Score: 142.80 E-value: 2.00e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 24 DLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLSIGGKIMNDVPAAQRGVAMVFQSYALFPHMTVFENMAFG--- 100
Cdd:PRK10771 19 DLTVERGERVAILGPSGAGKSTLLNLIAGFLTPASGSLTLNGQDHTTTPPSRRPVSMLFQENNLFSHLTVAQNIGLGlnp 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 101 -LKLAKTPKEeidrKVREAARVLQLEALLERRPKALSGGQRQRVAIGRAIVRQPGVFLFDEPLSNLDATLRGqtriEIAR 179
Cdd:PRK10771 99 gLKLNAAQRE----KLHAIARQMGIEDLLARLPGQLSGGQRQRVALARCLVREQPILLLDEPFSALDPALRQ----EMLT 170
|
170 180 190
....*....|....*....|....*....|....*..
gi 928002514 180 LHKQFA---KASVVYVTHDQIEAMTLADKIVLLHAGK 213
Cdd:PRK10771 171 LVSQVCqerQLTLLMVSHSLEDAARIAPRSLVVADGR 207
|
|
| thiQ |
TIGR01277 |
thiamine ABC transporter, ATP-binding protein; This model describes the energy-transducing ... |
24-213 |
3.83e-40 |
|
thiamine ABC transporter, ATP-binding protein; This model describes the energy-transducing ATPase subunit ThiQ of the ThiBPQ thiamine (and thiamine pyrophosphate) ABC transporter in several Proteobacteria. This protein is found so far only in Proteobacteria, and is found in complete genomes only if the ThiB and ThiP subunits are also found. [Transport and binding proteins, Other]
Pssm-ID: 130344 [Multi-domain] Cd Length: 213 Bit Score: 141.54 E-value: 3.83e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 24 DLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLSIGGKIMNDVPAAQRGVAMVFQSYALFPHMTVFENMAFGLKL 103
Cdd:TIGR01277 18 DLNVADGEIVAIMGPSGAGKSTLLNLIAGFIEPASGSIKVNDQSHTGLAPYQRPVSMLFQENNLFAHLTVRQNIGLGLHP 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 104 AKTPKEEIDRKVREAARVLQLEALLERRPKALSGGQRQRVAIGRAIVRQPGVFLFDEPLSNLDATLRGQTRIEIARLHKQ 183
Cdd:TIGR01277 98 GLKLNAEQQEKVVDAAQQVGIADYLDRLPEQLSGGQRQRVALARCLVRPNPILLLDEPFSALDPLLREEMLALVKQLCSE 177
|
170 180 190
....*....|....*....|....*....|
gi 928002514 184 fAKASVVYVTHDQIEAMTLADKIVLLHAGK 213
Cdd:TIGR01277 178 -RQRTLLMVTHHLSDARAIASQIAVVSQGK 206
|
|
| ABC_tran |
pfam00005 |
ABC transporter; ABC transporters for a large family of proteins responsible for translocation ... |
20-163 |
8.02e-40 |
|
ABC transporter; ABC transporters for a large family of proteins responsible for translocation of a variety of compounds across biological membranes. ABC transporters are the largest family of proteins in many completely sequenced bacteria. ABC transporters are composed of two copies of this domain and two copies of a transmembrane domain pfam00664. These four domains may belong to a single polypeptide or belong in different polypeptide chains.
Pssm-ID: 394964 [Multi-domain] Cd Length: 150 Bit Score: 138.55 E-value: 8.02e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 20 IRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLSIGGKIMN--DVPAAQRGVAMVFQSYALFPHMTVFENM 97
Cdd:pfam00005 1 LKNVSLTLNPGEILALVGPNGAGKSTLLKLIAGLLSPTEGTILLDGQDLTddERKSLRKEIGYVFQDPQLFPRLTVRENL 80
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 98 AFGLKLAKTPKEEIDRKVREAARVLQLEALLERR----PKALSGGQRQRVAIGRAIVRQPGVFLFDEPLS 163
Cdd:pfam00005 81 RLGLLLKGLSKREKDARAEEALEKLGLGDLADRPvgerPGTLSGGQRQRVAIARALLTKPKLLLLDEPTA 150
|
|
| ABCC_MRP_Like |
cd03228 |
ATP-binding cassette domain of multidrug resistance protein-like transporters; The MRP ... |
4-213 |
1.30e-39 |
|
ATP-binding cassette domain of multidrug resistance protein-like transporters; The MRP (Multidrug Resistance Protein)-like transporters are involved in drug, peptide, and lipid export. They belong to the subfamily C of the ATP-binding cassette (ABC) superfamily of transport proteins. The ABCC subfamily contains transporters with a diverse functional spectrum that includes ion transport, cell surface receptor, and toxin secretion activities. The MRP-like family, similar to all ABC proteins, have a common four-domain core structure constituted by two membrane-spanning domains, each composed of six transmembrane (TM) helices, and two nucleotide-binding domains (NBD). ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213195 [Multi-domain] Cd Length: 171 Bit Score: 138.67 E-value: 1.30e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 4 ISLRGVQKAYGDG-APVIRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLSIGGKIMNDVPAA--QRGVAM 80
Cdd:cd03228 1 IEFKNVSFSYPGRpKPVLKDVSLTIKPGEKVAIVGPSGSGKSTLLKLLLRLYDPTSGEILIDGVDLRDLDLEslRKNIAY 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 81 VFQSYALFpHMTVFENMafglklaktpkeeidrkvreaarvlqleallerrpkaLSGGQRQRVAIGRAIVRQPGVFLFDE 160
Cdd:cd03228 81 VPQDPFLF-SGTIRENI-------------------------------------LSGGQRQRIAIARALLRDPPILILDE 122
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 928002514 161 PLSNLDAtlrgQTRIEI-ARLHKQFAKASVVYVTHDqIEAMTLADKIVLLHAGK 213
Cdd:cd03228 123 ATSALDP----ETEALIlEALRALAKGKTVIVIAHR-LSTIRDADRIIVLDDGR 171
|
|
| artP |
PRK11124 |
arginine transporter ATP-binding subunit; Provisional |
3-216 |
1.46e-39 |
|
arginine transporter ATP-binding subunit; Provisional
Pssm-ID: 182980 [Multi-domain] Cd Length: 242 Bit Score: 140.92 E-value: 1.46e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 3 SISLRGVQKAYGDgAPVIRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLSIGGKIMN--------DVPAA 74
Cdd:PRK11124 2 SIQLNGINCFYGA-HQALFDITLDCPQGETLVLLGPSGAGKSSLLRVLNLLEMPRSGTLNIAGNHFDfsktpsdkAIREL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 75 QRGVAMVFQSYALFPHMTVFENMAFG-LKLAKTPKEEIDRKVREAARVLQLEALLERRPKALSGGQRQRVAIGRAIVRQP 153
Cdd:PRK11124 81 RRNVGMVFQQYNLWPHLTVQQNLIEApCRVLGLSKDQALARAEKLLERLRLKPYADRFPLHLSGGQQQRVAIARALMMEP 160
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 928002514 154 GVFLFDEPLSNLDATLRGQtrieIARLHKQFAKASV--VYVTHDQIEAMTLADKIVLLHAGKDTE 216
Cdd:PRK11124 161 QVLLFDEPTAALDPEITAQ----IVSIIRELAETGItqVIVTHEVEVARKTASRVVYMENGHIVE 221
|
|
| MdlB |
COG1132 |
ABC-type multidrug transport system, ATPase and permease component [Defense mechanisms]; |
3-230 |
4.16e-39 |
|
ABC-type multidrug transport system, ATPase and permease component [Defense mechanisms];
Pssm-ID: 440747 [Multi-domain] Cd Length: 579 Bit Score: 146.85 E-value: 4.16e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 3 SISLRGVQKAYGDGAPVIRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLSIGGKIMNDVPAAQ--RGVAM 80
Cdd:COG1132 339 EIEFENVSFSYPGDRPVLKDISLTIPPGETVALVGPSGSGKSTLVNLLLRFYDPTSGRILIDGVDIRDLTLESlrRQIGV 418
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 81 VFQSYALFpHMTVFENMAFGlklaktpKEEIDR-KVREAARVLQLEALLERRPK-----------ALSGGQRQRVAIGRA 148
Cdd:COG1132 419 VPQDTFLF-SGTIRENIRYG-------RPDATDeEVEEAAKAAQAHEFIEALPDgydtvvgergvNLSGGQRQRIAIARA 490
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 149 IVRQPGVFLFDEPLSNLDAtlrgQTRIEIAR-LHKQFAKASVVYVTHdQIEAMTLADKIVLLHAGKdterygsIAQIGAP 227
Cdd:COG1132 491 LLKDPPILILDEATSALDT----ETEALIQEaLERLMKGRTTIVIAH-RLSTIRNADRILVLDDGR-------IVEQGTH 558
|
...
gi 928002514 228 LEL 230
Cdd:COG1132 559 EEL 561
|
|
| CydD |
COG4988 |
ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease ... |
3-233 |
8.78e-39 |
|
ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 444012 [Multi-domain] Cd Length: 563 Bit Score: 145.67 E-value: 8.78e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 3 SISLRGVQKAYGDGAPVIRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLSIGGKIMNDVPAA--QRGVAM 80
Cdd:COG4988 336 SIELEDVSFSYPGGRPALDGLSLTIPPGERVALVGPSGAGKSTLLNLLLGFLPPYSGSILINGVDLSDLDPAswRRQIAW 415
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 81 VFQSYALFpHMTVFENMAFGLKLAktPKEEIdrkvREAARVLQLEALLERRPK-----------ALSGGQRQRVAIGRAI 149
Cdd:COG4988 416 VPQNPYLF-AGTIRENLRLGRPDA--SDEEL----EAALEAAGLDEFVAALPDgldtplgeggrGLSGGQAQRLALARAL 488
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 150 VRQPGVFLFDEPLSNLDAtlrgQTRIEI-ARLHKQFAKASVVYVTHDqIEAMTLADKIVLLHAGKdterygsIAQIGAPL 228
Cdd:COG4988 489 LRDAPLLLLDEPTAHLDA----ETEAEIlQALRRLAKGRTVILITHR-LALLAQADRILVLDDGR-------IVEQGTHE 556
|
....*
gi 928002514 229 ELYHR 233
Cdd:COG4988 557 ELLAK 561
|
|
| ABC_ATPase |
cd00267 |
ATP-binding cassette transporter nucleotide-binding domain; ABC transporters are a large ... |
5-213 |
1.28e-38 |
|
ATP-binding cassette transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213179 [Multi-domain] Cd Length: 157 Bit Score: 135.84 E-value: 1.28e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 5 SLRGVQKAYGDGaPVIRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLSIGGKIMNDVP--AAQRGVAMVF 82
Cdd:cd00267 1 EIENLSFRYGGR-TALDNVSLTLKAGEIVALVGPNGSGKSTLLRAIAGLLKPTSGEILIDGKDIAKLPleELRRRIGYVP 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 83 QsyalfphmtvfenmafglklaktpkeeidrkvreaarvlqleallerrpkaLSGGQRQRVAIGRAIVRQPGVFLFDEPL 162
Cdd:cd00267 80 Q---------------------------------------------------LSGGQRQRVALARALLLNPDLLLLDEPT 108
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 928002514 163 SNLDATLRGQTRIEIARLHKQfaKASVVYVTHDQIEAMTLADKIVLLHAGK 213
Cdd:cd00267 109 SGLDPASRERLLELLRELAEE--GRTVIIVTHDPELAELAADRVIVLKDGK 157
|
|
| PRK10070 |
PRK10070 |
proline/glycine betaine ABC transporter ATP-binding protein ProV; |
20-242 |
2.10e-38 |
|
proline/glycine betaine ABC transporter ATP-binding protein ProV;
Pssm-ID: 182221 [Multi-domain] Cd Length: 400 Bit Score: 142.09 E-value: 2.10e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 20 IRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLSIGGKIMNDVPAAQ------RGVAMVFQSYALFPHMTV 93
Cdd:PRK10070 44 VKDASLAIEEGEIFVIMGLSGSGKSTMVRLLNRLIEPTRGQVLIDGVDIAKISDAElrevrrKKIAMVFQSFALMPHMTV 123
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 94 FENMAFGLKLAKTPKEEIDRKVREAARVLQLEALLERRPKALSGGQRQRVAIGRAIVRQPGVFLFDEPLSNLDATLRGQT 173
Cdd:PRK10070 124 LDNTAFGMELAGINAEERREKALDALRQVGLENYAHSYPDELSGGMRQRVGLARALAINPDILLMDEAFSALDPLIRTEM 203
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 928002514 174 RIEIARLHKQFAKaSVVYVTHDQIEAMTLADKIVLLHAGKdterygsIAQIGAPLELYHRPKSRFVAGF 242
Cdd:PRK10070 204 QDELVKLQAKHQR-TIVFISHDLDEAMRIGDRIAIMQNGE-------VVQVGTPDEILNNPANDYVRTF 264
|
|
| ABC_Mj1267_LivG_branched |
cd03219 |
ATP-binding cassette component of branched chain amino acids transport system; The Mj1267/LivG ... |
4-213 |
4.96e-38 |
|
ATP-binding cassette component of branched chain amino acids transport system; The Mj1267/LivG ABC transporter subfamily is involved in the transport of the hydrophobic amino acids leucine, isoleucine and valine. MJ1267 is a branched-chain amino acid transporter with 29% similarity to both the LivF and LivG components of the E. coli branched-chain amino acid transporter. MJ1267 contains an insertion from residues 114 to 123 characteristic of LivG (Leucine-Isoleucine-Valine) homologs. The branched-chain amino acid transporter from E. coli comprises a heterodimer of ABCs (LivF and LivG), a heterodimer of six-helix TM domains (LivM and LivH), and one of two alternative soluble periplasmic substrate binding proteins (LivK or LivJ).
Pssm-ID: 213186 [Multi-domain] Cd Length: 236 Bit Score: 136.80 E-value: 4.96e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 4 ISLRGVQKAYGdGAPVIRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLSIGGKIMNDVPA---AQRGVAM 80
Cdd:cd03219 1 LEVRGLTKRFG-GLVALDDVSFSVRPGEIHGLIGPNGAGKTTLFNLISGFLRPTSGSVLFDGEDITGLPPheiARLGIGR 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 81 VFQSYALFPHMTVFENM----------AFGLKLAKTPKEEIDRKVREAARVLQLEALLERRPKALSGGQRQRVAIGRAIV 150
Cdd:cd03219 80 TFQIPRLFPELTVLENVmvaaqartgsGLLLARARREEREARERAEELLERVGLADLADRPAGELSYGQQRRLEIARALA 159
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 928002514 151 RQPGVFLFDEPLSNLDATLRGQTRIEIARLHKQfaKASVVYVTHDQIEAMTLADKIVLLHAGK 213
Cdd:cd03219 160 TDPKLLLLDEPAAGLNPEETEELAELIRELRER--GITVLLVEHDMDVVMSLADRVTVLDQGR 220
|
|
| PRK14267 |
PRK14267 |
phosphate ABC transporter ATP-binding protein; Provisional |
1-244 |
5.43e-38 |
|
phosphate ABC transporter ATP-binding protein; Provisional
Pssm-ID: 184596 [Multi-domain] Cd Length: 253 Bit Score: 137.28 E-value: 5.43e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 1 MASISLRGVQKAYGDGApVIRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLT-----DGDLSIGGKIM--NDVPA 73
Cdd:PRK14267 2 KFAIETVNLRVYYGSNH-VIKGVDLKIPQNGVFALMGPSGCGKSTLLRTFNRLLELNeearvEGEVRLFGRNIysPDVDP 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 74 --AQRGVAMVFQSYALFPHMTVFENMAFGLKLAK--TPKEEIDRKVR----EAARVLQLEALLERRPKALSGGQRQRVAI 145
Cdd:PRK14267 81 ieVRREVGMVFQYPNPFPHLTIYDNVAIGVKLNGlvKSKKELDERVEwalkKAALWDEVKDRLNDYPSNLSGGQRQRLVI 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 146 GRAIVRQPGVFLFDEPLSNLDATlrGQTRIE--IARLHKQFakaSVVYVTHDQIEAMTLADKIVLLHAGKdterygsIAQ 223
Cdd:PRK14267 161 ARALAMKPKILLMDEPTANIDPV--GTAKIEelLFELKKEY---TIVLVTHSPAQAARVSDYVAFLYLGK-------LIE 228
|
250 260
....*....|....*....|....*
gi 928002514 224 IGAPLELYHRPK----SRFVAGFIG 244
Cdd:PRK14267 229 VGPTRKVFENPEheltEKYVTGALG 253
|
|
| CcmA |
COG4133 |
ABC-type transport system involved in cytochrome c biogenesis, ATPase component ... |
2-213 |
9.86e-38 |
|
ABC-type transport system involved in cytochrome c biogenesis, ATPase component [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 443308 [Multi-domain] Cd Length: 206 Bit Score: 134.91 E-value: 9.86e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 2 ASISLRGVQKAYGDgAPVIRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLSIGGK-IMNDVPAAQRGVAM 80
Cdd:COG4133 1 MMLEAENLSCRRGE-RLLFSGLSFTLAAGEALALTGPNGSGKTTLLRILAGLLPPSAGEVLWNGEpIRDAREDYRRRLAY 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 81 VFQSYALFPHMTVFENMAFGLKLAKTPKEEIDrkVREAARVLQLEALLERRPKALSGGQRQRVAIGRAIVRQPGVFLFDE 160
Cdd:COG4133 80 LGHADGLKPELTVRENLRFWAALYGLRADREA--IDEALEAVGLAGLADLPVRQLSAGQKRRVALARLLLSPAPLWLLDE 157
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 928002514 161 PLSNLDAtlRGQTRI-EIARLHKQfAKASVVYVTHDQIEAmtLADKIVLLHAGK 213
Cdd:COG4133 158 PFTALDA--AGVALLaELIAAHLA-RGGAVLLTTHQPLEL--AAARVLDLGDFK 206
|
|
| L_ocin_972_ABC |
TIGR03608 |
putative bacteriocin export ABC transporter, lactococcin 972 group; A gene pair with a fairly ... |
6-209 |
5.83e-37 |
|
putative bacteriocin export ABC transporter, lactococcin 972 group; A gene pair with a fairly wide distribution consists of a polypeptide related to the lactococcin 972 (see TIGR01653) and multiple-membrane-spanning putative immunity protein (see TIGR01654). This model represents a small clade within the ABC transporters that regularly are found adjacent to these bacteriocin system gene pairs and are likely serve as export proteins. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Unknown substrate]
Pssm-ID: 188353 [Multi-domain] Cd Length: 206 Bit Score: 132.74 E-value: 5.83e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 6 LRGVQKAYGDGApVIRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLSIGGKIMNDVPAAQRG------VA 79
Cdd:TIGR03608 1 LKNISKKFGDKV-ILDDLNLTIEKGKMYAIIGESGSGKSTLLNIIGLLEKFDSGQVYLNGQETPPLNSKKASkfrrekLG 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 80 MVFQSYALFPHMTVFENMAFGLKLAKTPKEEIDRKVREAARVLQLEALLERRPKALSGGQRQRVAIGRAIVRQPGVFLFD 159
Cdd:TIGR03608 80 YLFQNFALIENETVEENLDLGLKYKKLSKKEKREKKKEALEKVGLNLKLKQKIYELSGGEQQRVALARAILKPPPLILAD 159
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 928002514 160 EPLSNLDAtlrgQTRIEIARLHKQFAKA--SVVYVTHDQiEAMTLADKIVLL 209
Cdd:TIGR03608 160 EPTGSLDP----KNRDEVLDLLLELNDEgkTIIIVTHDP-EVAKQADRVIEL 206
|
|
| YbbA |
COG4181 |
Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase ... |
4-213 |
9.32e-37 |
|
Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component [Secondary metabolites biosynthesis, transport and catabolism];
Pssm-ID: 443338 [Multi-domain] Cd Length: 233 Bit Score: 133.33 E-value: 9.32e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 4 ISLRGVQKAYGDGA---PVIRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLSIGGKIMN----DVPAAQR 76
Cdd:COG4181 9 IELRGLTKTVGTGAgelTILKGISLEVEAGESVAIVGASGSGKSTLLGLLAGLDRPTSGTVRLAGQDLFaldeDARARLR 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 77 G--VAMVFQSYALFPHMTVFENMAFGLKLAKtpkeeiDRKVRE-AARVLQ---LEALLERRPKALSGGQRQRVAIGRAIV 150
Cdd:COG4181 89 ArhVGFVFQSFQLLPTLTALENVMLPLELAG------RRDARArARALLErvgLGHRLDHYPAQLSGGEQQRVALARAFA 162
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 928002514 151 RQPGVFLFDEPLSNLDATlRGQTRIE-IARLHKQfAKASVVYVTHDQieamTLA---DKIVLLHAGK 213
Cdd:COG4181 163 TEPAILFADEPTGNLDAA-TGEQIIDlLFELNRE-RGTTLVLVTHDP----ALAarcDRVLRLRAGR 223
|
|
| cbiO |
PRK13632 |
cobalt transporter ATP-binding subunit; Provisional |
2-230 |
1.43e-36 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 237452 [Multi-domain] Cd Length: 271 Bit Score: 133.96 E-value: 1.43e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 2 ASISLRGVQKAYGDG-APVIRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLSIGGKIMND--VPAAQRGV 78
Cdd:PRK13632 6 VMIKVENVSFSYPNSeNNALKNVSFEINEGEYVAILGHNGSGKSTISKILTGLLKPQSGEIKIDGITISKenLKEIRKKI 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 79 AMVFQSY-ALFPHMTVFENMAFGLKLAKTPKEEIDRKVREAARVLQLEALLERRPKALSGGQRQRVAIGRAIVRQPGVFL 157
Cdd:PRK13632 86 GIIFQNPdNQFIGATVEDDIAFGLENKKVPPKKMKDIIDDLAKKVGMEDYLDKEPQNLSGGQKQRVAIASVLALNPEIII 165
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 928002514 158 FDEPLSNLDAtlRGQTRIE--IARLHKQfAKASVVYVTHDQIEAmTLADKIVLLHAGKdterygsIAQIGAPLEL 230
Cdd:PRK13632 166 FDESTSMLDP--KGKREIKkiMVDLRKT-RKKTLISITHDMDEA-ILADKVIVFSEGK-------LIAQGKPKEI 229
|
|
| PRK11264 |
PRK11264 |
putative amino-acid ABC transporter ATP-binding protein YecC; Provisional |
1-235 |
2.25e-36 |
|
putative amino-acid ABC transporter ATP-binding protein YecC; Provisional
Pssm-ID: 183063 [Multi-domain] Cd Length: 250 Bit Score: 132.57 E-value: 2.25e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 1 MASISLRGVQKAYgDGAPVIRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLSIG----------GKIMND 70
Cdd:PRK11264 1 MSAIEVKNLVKKF-HGQTVLHGIDLEVKPGEVVAIIGPSGSGKTTLLRCINLLEQPEAGTIRVGditidtarslSQQKGL 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 71 VPAAQRGVAMVFQSYALFPHMTVFENMAFG-LKLAKTPKEEIDRKVREAARVLQLEALLERRPKALSGGQRQRVAIGRAI 149
Cdd:PRK11264 80 IRQLRQHVGFVFQNFNLFPHRTVLENIIEGpVIVKGEPKEEATARARELLAKVGLAGKETSYPRRLSGGQQQRVAIARAL 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 150 VRQPGVFLFDEPLSNLDATLRGQTRIEIARLHKQfaKASVVYVTHDQIEAMTLADKIVLLHAGKdterygsIAQIGAPLE 229
Cdd:PRK11264 160 AMRPEVILFDEPTSALDPELVGEVLNTIRQLAQE--KRTMVIVTHEMSFARDVADRAIFMDQGR-------IVEQGPAKA 230
|
....*.
gi 928002514 230 LYHRPK 235
Cdd:PRK11264 231 LFADPQ 236
|
|
| PRK14247 |
PRK14247 |
phosphate ABC transporter ATP-binding protein; Provisional |
1-241 |
4.30e-36 |
|
phosphate ABC transporter ATP-binding protein; Provisional
Pssm-ID: 172735 [Multi-domain] Cd Length: 250 Bit Score: 131.96 E-value: 4.30e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 1 MASISLRGVQKAYGDgAPVIRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDL-----TDGDLSIGGK--IMNDVPA 73
Cdd:PRK14247 1 MNKIEIRDLKVSFGQ-VEVLDGVNLEIPDNTITALMGPSGSGKSTLLRVFNRLIELypearVSGEVYLDGQdiFKMDVIE 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 74 AQRGVAMVFQSYALFPHMTVFENMAFGLKLAK--TPKEEIDRKVREAARVLQLEALLERRPKA----LSGGQRQRVAIGR 147
Cdd:PRK14247 80 LRRRVQMVFQIPNPIPNLSIFENVALGLKLNRlvKSKKELQERVRWALEKAQLWDEVKDRLDApagkLSGGQQQRLCIAR 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 148 AIVRQPGVFLFDEPLSNLDATLRGQTRIEIARLHKQFAkasVVYVTHDQIEAMTLADKIVLLHAGKdterygsIAQIGAP 227
Cdd:PRK14247 160 ALAFQPEVLLADEPTANLDPENTAKIESLFLELKKDMT---IVLVTHFPQQAARISDYVAFLYKGQ-------IVEWGPT 229
|
250
....*....|....*...
gi 928002514 228 LELYHRPK----SRFVAG 241
Cdd:PRK14247 230 REVFTNPRheltEKYVTG 247
|
|
| CydC |
COG4987 |
ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease ... |
2-237 |
5.82e-36 |
|
ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease components [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 444011 [Multi-domain] Cd Length: 569 Bit Score: 137.98 E-value: 5.82e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 2 ASISLRGVQKAY-GDGAPVIRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLSIGGKIMNDVPAAQ--RGV 78
Cdd:COG4987 332 PSLELEDVSFRYpGAGRPVLDGLSLTLPPGERVAIVGPSGSGKSTLLALLLRFLDPQSGSITLGGVDLRDLDEDDlrRRI 411
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 79 AMVFQSYALFpHMTVFENmafgLKLAktpKEEI-DRKVREAARVLQLEALLERRPK-----------ALSGGQRQRVAIG 146
Cdd:COG4987 412 AVVPQRPHLF-DTTLREN----LRLA---RPDAtDEELWAALERVGLGDWLAALPDgldtwlgeggrRLSGGERRRLALA 483
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 147 RAIVRQPGVFLFDEPLSNLDAtlrgQTRIEI-ARLHKQFAKASVVYVTHDQiEAMTLADKIVLLHAGKDTERyGSIAQIG 225
Cdd:COG4987 484 RALLRDAPILLLDEPTEGLDA----ATEQALlADLLEALAGRTVLLITHRL-AGLERMDRILVLEDGRIVEQ-GTHEELL 557
|
250
....*....|..
gi 928002514 226 APLELYHRPKSR 237
Cdd:COG4987 558 AQNGRYRQLYQR 569
|
|
| HisP |
COG4598 |
ABC-type histidine transport system, ATPase component [Amino acid transport and metabolism]; |
4-245 |
8.02e-36 |
|
ABC-type histidine transport system, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 443652 [Multi-domain] Cd Length: 259 Bit Score: 131.46 E-value: 8.02e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 4 ISLRGVQKAYGDgAPVIRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLSIGGKIM--------NDVPAAQ 75
Cdd:COG4598 9 LEVRDLHKSFGD-LEVLKGVSLTARKGDVISIIGSSGSGKSTFLRCINLLETPDSGEIRVGGEEIrlkpdrdgELVPADR 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 76 RGV-------AMVFQSYALFPHMTVFENMAFG-LKLAKTPKEEidrkVREAARVLqLE--ALLERR---PKALSGGQRQR 142
Cdd:COG4598 88 RQLqrirtrlGMVFQSFNLWSHMTVLENVIEApVHVLGRPKAE----AIERAEAL-LAkvGLADKRdayPAHLSGGQQQR 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 143 VAIGRAIVRQPGVFLFDEPLSNLDATLRGqtriEIARLHKQFAK--ASVVYVTHDQIEAMTLADKIVLLHAGKdterygs 220
Cdd:COG4598 163 AAIARALAMEPEVMLFDEPTSALDPELVG----EVLKVMRDLAEegRTMLVVTHEMGFARDVSSHVVFLHQGR------- 231
|
250 260
....*....|....*....|....*
gi 928002514 221 IAQIGAPLELYHRPKSRFVAGFIGS 245
Cdd:COG4598 232 IEEQGPPAEVFGNPKSERLRQFLSS 256
|
|
| ABC_phnC |
TIGR02315 |
phosphonate ABC transporter, ATP-binding protein; Phosphonates are a class of ... |
4-213 |
8.87e-36 |
|
phosphonate ABC transporter, ATP-binding protein; Phosphonates are a class of phosphorus-containing organic compound with a stable direct C-P bond rather than a C-O-P linkage. A number of bacterial species have operons, typically about 14 genes in size, with genes for ATP-dependent transport of phosphonates, degradation, and regulation of the expression of the system. Members of this protein family are the ATP-binding cassette component of tripartite ABC transporters of phosphonates. [Transport and binding proteins, Anions]
Pssm-ID: 131368 [Multi-domain] Cd Length: 243 Bit Score: 130.88 E-value: 8.87e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 4 ISLRGVQKAYGDGAPVIRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLSIGGKIMNDVPA-----AQRGV 78
Cdd:TIGR02315 2 LEVENLSKVYPNGKQALKNINLNINPGEFVAIIGPSGAGKSTLLRCINRLVEPSSGSILLEGTDITKLRGkklrkLRRRI 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 79 AMVFQSYALFPHMTVFENMAFGLKLAKT---------PKEEIDRKVREAARVlQLEALLERRPKALSGGQRQRVAIGRAI 149
Cdd:TIGR02315 82 GMIFQHYNLIERLTVLENVLHGRLGYKPtwrsllgrfSEEDKERALSALERV-GLADKAYQRADQLSGGQQQRVAIARAL 160
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 928002514 150 VRQPGVFLFDEPLSNLDATLRGQTRIEIARLHKQFAKASVVYVtHDQIEAMTLADKIVLLHAGK 213
Cdd:TIGR02315 161 AQQPDLILADEPIASLDPKTSKQVMDYLKRINKEDGITVIINL-HQVDLAKKYADRIVGLKAGE 223
|
|
| modC |
PRK11144 |
molybdenum ABC transporter ATP-binding protein ModC; |
22-213 |
1.19e-35 |
|
molybdenum ABC transporter ATP-binding protein ModC;
Pssm-ID: 182993 [Multi-domain] Cd Length: 352 Bit Score: 133.46 E-value: 1.19e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 22 DVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLSIGGKIMND------VPAAQRGVAMVFQSYALFPHMTVFE 95
Cdd:PRK11144 16 TVNLTLPAQGITAIFGRSGAGKTSLINAISGLTRPQKGRIVLNGRVLFDaekgicLPPEKRRIGYVFQDARLFPHYKVRG 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 96 NMAFGLKlaKTPKEEIDRKVReaarVLQLEALLERRPKALSGGQRQRVAIGRAIVRQPGVFLFDEPLSNLDATLRGQTRI 175
Cdd:PRK11144 96 NLRYGMA--KSMVAQFDKIVA----LLGIEPLLDRYPGSLSGGEKQRVAIGRALLTAPELLLMDEPLASLDLPRKRELLP 169
|
170 180 190
....*....|....*....|....*....|....*...
gi 928002514 176 EIARLHKQFaKASVVYVTHDQIEAMTLADKIVLLHAGK 213
Cdd:PRK11144 170 YLERLAREI-NIPILYVSHSLDEILRLADRVVVLEQGK 206
|
|
| ABC_Iron-Siderophores_B12_Hemin |
cd03214 |
ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related ... |
5-213 |
2.13e-35 |
|
ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; ABC transporters, involved in the uptake of siderophores, heme, and vitamin B12, are widely conserved in bacteria and archaea. Only very few species lack representatives of the siderophore family transporters. The E. coli BtuCD protein is an ABC transporter mediating vitamin B12 uptake. The two ATP-binding cassettes (BtuD) are in close contact with each other, as are the two membrane-spanning subunits (BtuC); this arrangement is distinct from that observed for the E. coli lipid flippase MsbA. The BtuC subunits provide 20 transmembrane helices grouped around a translocation pathway that is closed to the cytoplasm by a gate region, whereas the dimer arrangement of the BtuD subunits resembles the ATP-bound form of the Rad50 DNA repair enzyme. A prominent cytoplasmic loop of BtuC forms the contact region with the ATP-binding cassette and represent a conserved motif among the ABC transporters.
Pssm-ID: 213181 [Multi-domain] Cd Length: 180 Bit Score: 127.94 E-value: 2.13e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 5 SLRGVQKAYGdGAPVIRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLSIGGKIMNDVPAAQRG--VAMVF 82
Cdd:cd03214 1 EVENLSVGYG-GRTVLDDLSLSIEAGEIVGILGPNGAGKSTLLKTLAGLLKPSSGEILLDGKDLASLSPKELArkIAYVP 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 83 QsyalfphmtvfenmafglklaktpkeeidrkvreAARVLQLEALLERRPKALSGGQRQRVAIGRAIVRQPGVFLFDEPL 162
Cdd:cd03214 80 Q----------------------------------ALELLGLAHLADRPFNELSGGERQRVLLARALAQEPPILLLDEPT 125
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 928002514 163 SNLDatLRGQTRI--EIARLHKQFAKAsVVYVTHDQIEAMTLADKIVLLHAGK 213
Cdd:cd03214 126 SHLD--IAHQIELleLLRRLARERGKT-VVMVLHDLNLAARYADRVILLKDGR 175
|
|
| ABC_NatA_sodium_exporter |
cd03266 |
ATP-binding cassette domain of the Na+ transporter; NatA is the ATPase component of a ... |
4-213 |
2.73e-34 |
|
ATP-binding cassette domain of the Na+ transporter; NatA is the ATPase component of a bacterial ABC-type Na+ transport system called NatAB, which catalyzes ATP-dependent electrogenic Na+ extrusion without mechanically coupled proton or K+ uptake. NatB possess six putative membrane spanning regions at its C-terminus. In B. subtilis, NatAB is inducible by agents such as ethanol and protonophores, which lower the proton-motive force across the membrane. The closest sequence similarity to NatA is exhibited by DrrA of the two-component daunorubicin- and doxorubicin-efflux system. Hence, the functional NatAB is presumably assembled with two copies of a single ATP-binding protein and a single integral membrane protein.
Pssm-ID: 213233 [Multi-domain] Cd Length: 218 Bit Score: 126.33 E-value: 2.73e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 4 ISLRGVQKAYGDGAPVI---RDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLSIGGKIMNDVP-AAQRGVA 79
Cdd:cd03266 2 ITADALTKRFRDVKKTVqavDGVSFTVKPGEVTGLLGPNGAGKTTTLRMLAGLLEPDAGFATVDGFDVVKEPaEARRRLG 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 80 MVFQSYALFPHMTVFENMAFGLKLAKTPKEEIDRKVREAARVLQLEALLERRPKALSGGQRQRVAIGRAIVRQPGVFLFD 159
Cdd:cd03266 82 FVSDSTGLYDRLTARENLEYFAGLYGLKGDELTARLEELADRLGMEELLDRRVGGFSTGMRQKVAIARALVHDPPVLLLD 161
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 928002514 160 EPLSNLDATLRgQTRIEIARLHKQFAKAsVVYVTHDQIEAMTLADKIVLLHAGK 213
Cdd:cd03266 162 EPTTGLDVMAT-RALREFIRQLRALGKC-ILFSTHIMQEVERLCDRVVVLHRGR 213
|
|
| LolD_lipo_ex |
TIGR02211 |
lipoprotein releasing system, ATP-binding protein; This model represents LolD, a member of the ... |
4-206 |
1.38e-33 |
|
lipoprotein releasing system, ATP-binding protein; This model represents LolD, a member of the ABC transporter family (pfam00005). LolD is involved in localization of lipoproteins in some bacteria. It works with a transmembrane protein LolC, which in some species is a paralogous pair LolC and LolE. Depending on whether the residue immediately following the new, modified N-terminal Cys residue, the nascent lipoprotein may be carried further by LolA and LolB to the outer membrane, or remain at the inner membrane. The top scoring proteins excluded by this model include homologs from the archaeal genus Methanosarcina. [Protein fate, Protein and peptide secretion and trafficking]
Pssm-ID: 131266 [Multi-domain] Cd Length: 221 Bit Score: 124.39 E-value: 1.38e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 4 ISLRGVQKAYGDGA---PVIRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLSIGGKIMNDVPAAQRG--- 77
Cdd:TIGR02211 2 LKCENLGKRYQEGKldtRVLKGVSLSIGKGEIVAIVGSSGSGKSTLLHLLGGLDNPTSGEVLFNGQSLSKLSSNERAklr 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 78 ---VAMVFQSYALFPHMTVFENMAFGLKLAKTPKEEIDRKVREAARVLQLEALLERRPKALSGGQRQRVAIGRAIVRQPG 154
Cdd:TIGR02211 82 nkkLGFIYQFHHLLPDFTALENVAMPLLIGKKSVKEAKERAYEMLEKVGLEHRINHRPSELSGGERQRVAIARALVNQPS 161
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 928002514 155 VFLFDEPLSNLDATLRGQTRIEIARLHKQFaKASVVYVTHDqieaMTLADKI 206
Cdd:TIGR02211 162 LVLADEPTGNLDNNNAKIIFDLMLELNREL-NTSFLVVTHD----LELAKKL 208
|
|
| metN |
PRK11153 |
DL-methionine transporter ATP-binding subunit; Provisional |
4-245 |
1.71e-33 |
|
DL-methionine transporter ATP-binding subunit; Provisional
Pssm-ID: 236863 [Multi-domain] Cd Length: 343 Bit Score: 127.22 E-value: 1.71e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 4 ISLRGVQKAYGDGAPVI---RDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLSIGGKIM-----NDVPAAQ 75
Cdd:PRK11153 2 IELKNISKVFPQGGRTIhalNNVSLHIPAGEIFGVIGASGAGKSTLIRCINLLERPTSGRVLVDGQDLtalseKELRKAR 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 76 RGVAMVFQSYALFPHMTVFENMAFGLKLAKTPKEEIDRKVREAARVLQLEALLERRPKALSGGQRQRVAIGRAIVRQPGV 155
Cdd:PRK11153 82 RQIGMIFQHFNLLSSRTVFDNVALPLELAGTPKAEIKARVTELLELVGLSDKADRYPAQLSGGQKQRVAIARALASNPKV 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 156 FLFDEPLSNLDAtlrgQTRIEIARLHKQFAKA---SVVYVTHdQIEAM-TLADKIVLLHAGKdterygsIAQIGAPLELY 231
Cdd:PRK11153 162 LLCDEATSALDP----ATTRSILELLKDINRElglTIVLITH-EMDVVkRICDRVAVIDAGR-------LVEQGTVSEVF 229
|
250
....*....|....
gi 928002514 232 HRPKSRFVAGFIGS 245
Cdd:PRK11153 230 SHPKHPLTREFIQS 243
|
|
| cbiO |
PRK13637 |
energy-coupling factor transporter ATPase; |
3-231 |
2.17e-33 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 237455 [Multi-domain] Cd Length: 287 Bit Score: 125.93 E-value: 2.17e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 3 SISLRGVQKAYGDGAP----VIRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLSIGG------KI-MNDV 71
Cdd:PRK13637 2 SIKIENLTHIYMEGTPfekkALDNVNIEIEDGEFVGLIGHTGSGKSTLIQHLNGLLKPTSGKIIIDGvditdkKVkLSDI 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 72 paaQRGVAMVFQ--SYALFPHmTVFENMAFGLKLAKTPKEEIDRKVREAARVLQL--EALLERRPKALSGGQRQRVAIGR 147
Cdd:PRK13637 82 ---RKKVGLVFQypEYQLFEE-TIEKDIAFGPINLGLSEEEIENRVKRAMNIVGLdyEDYKDKSPFELSGGQKRRVAIAG 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 148 AIVRQPGVFLFDEPLSNLDATLRGQTRIEIARLHKQFaKASVVYVTHDQIEAMTLADKIVLLHAGKdterygsIAQIGAP 227
Cdd:PRK13637 158 VVAMEPKILILDEPTAGLDPKGRDEILNKIKELHKEY-NMTIILVSHSMEDVAKLADRIIVMNKGK-------CELQGTP 229
|
....
gi 928002514 228 LELY 231
Cdd:PRK13637 230 REVF 233
|
|
| ABCC_ATM1_transporter |
cd03253 |
ATP-binding cassette domain of iron-sulfur clusters transporter, subfamily C; ATM1 is an ABC ... |
4-230 |
3.84e-33 |
|
ATP-binding cassette domain of iron-sulfur clusters transporter, subfamily C; ATM1 is an ABC transporter that is expressed in the mitochondria. Although the specific function of ATM1 is unknown, its disruption results in the accumulation of excess mitochondrial iron, loss of mitochondrial cytochromes, oxidative damage to mitochondrial DNA, and decreased levels of cytosolic heme proteins. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213220 [Multi-domain] Cd Length: 236 Bit Score: 123.88 E-value: 3.84e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 4 ISLRGVQKAYGDGAPVIRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLSIGGKIMNDV--PAAQRGVAMV 81
Cdd:cd03253 1 IEFENVTFAYDPGRPVLKDVSFTIPAGKKVAIVGPSGSGKSTILRLLFRFYDVSSGSILIDGQDIREVtlDSLRRAIGVV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 82 FQSYALFpHMTVFENMAFGlKLAKTPKEeidrkVREAARVLQLEALLERRPKA-----------LSGGQRQRVAIGRAIV 150
Cdd:cd03253 81 PQDTVLF-NDTIGYNIRYG-RPDATDEE-----VIEAAKAAQIHDKIMRFPDGydtivgerglkLSGGEKQRVAIARAIL 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 151 RQPGVFLFDEPLSNLDATlrgqTRIEI-ARLHKQFAKASVVYVTHDQIEAMTlADKIVLLHAGKdterygsIAQIGAPLE 229
Cdd:cd03253 154 KNPPILLLDEATSALDTH----TEREIqAALRDVSKGRTTIVIAHRLSTIVN-ADKIIVLKDGR-------IVERGTHEE 221
|
.
gi 928002514 230 L 230
Cdd:cd03253 222 L 222
|
|
| ABC_Metallic_Cations |
cd03235 |
ATP-binding cassette domain of the metal-type transporters; This family includes transporters ... |
15-209 |
5.73e-33 |
|
ATP-binding cassette domain of the metal-type transporters; This family includes transporters involved in the uptake of various metallic cations such as iron, manganese, and zinc. The ATPases of this group of transporters are very similar to members of iron-siderophore uptake family suggesting that they share a common ancestor. The best characterized metal-type ABC transporters are the YfeABCD system of Y. pestis, the SitABCD system of Salmonella enterica serovar Typhimurium, and the SitABCD transporter of Shigella flexneri. Moreover other uncharacterized homologs of these metal-type transporters are mainly found in pathogens like Haemophilus or enteroinvasive E. coli isolates.
Pssm-ID: 213202 [Multi-domain] Cd Length: 213 Bit Score: 122.64 E-value: 5.73e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 15 DGAPVIRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLSIGGKimnDVPAAQRGVAMVFQSYAL---FPhM 91
Cdd:cd03235 10 GGHPVLEDVSFEVKPGEFLAIVGPNGAGKSTLLKAILGLLKPTSGSIRVFGK---PLEKERKRIGYVPQRRSIdrdFP-I 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 92 TVFENMAFGL----KLAKTPKEEIDRKVREAARVLQLEALLERRPKALSGGQRQRVAIGRAIVRQPGVFLFDEPLSNLDA 167
Cdd:cd03235 86 SVRDVVLMGLyghkGLFRRLSKADKAKVDEALERVGLSELADRQIGELSGGQQQRVLLARALVQDPDLLLLDEPFAGVDP 165
|
170 180 190 200
....*....|....*....|....*....|....*....|....
gi 928002514 168 tlrgQTRIEIARLHKQFAKA--SVVYVTHDQIEAMTLADKIVLL 209
Cdd:cd03235 166 ----KTQEDIYELLRELRREgmTILVVTHDLGLVLEYFDRVLLL 205
|
|
| MglA |
COG1129 |
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; |
4-213 |
1.57e-32 |
|
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];
Pssm-ID: 440745 [Multi-domain] Cd Length: 497 Bit Score: 127.44 E-value: 1.57e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 4 ISLRGVQKAYGdGAPVIRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLSIGGK---IMNDVPAAQRGVAM 80
Cdd:COG1129 5 LEMRGISKSFG-GVKALDGVSLELRPGEVHALLGENGAGKSTLMKILSGVYQPDSGEILLDGEpvrFRSPRDAQAAGIAI 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 81 VFQSYALFPHMTVFENMAFGLKLAKTPKeeIDRK--VREAARVLQ---LEALLERRPKALSGGQRQRVAIGRAIVRQPGV 155
Cdd:COG1129 84 IHQELNLVPNLSVAENIFLGREPRRGGL--IDWRamRRRARELLArlgLDIDPDTPVGDLSVAQQQLVEIARALSRDARV 161
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 928002514 156 FLFDEPLSNLDATlrgqtriEIARLHKQFAK-----ASVVYVTHDQIEAMTLADKIVLLHAGK 213
Cdd:COG1129 162 LILDEPTASLTER-------EVERLFRIIRRlkaqgVAIIYISHRLDEVFEIADRVTVLRDGR 217
|
|
| ABC_BcrA_bacitracin_resist |
cd03268 |
ATP-binding cassette domain of the bacitracin-resistance transporter; The BcrA subfamily ... |
4-213 |
3.09e-32 |
|
ATP-binding cassette domain of the bacitracin-resistance transporter; The BcrA subfamily represents ABC transporters involved in peptide antibiotic resistance. Bacitracin is a dodecapeptide antibiotic produced by B. licheniformis and B. subtilis. The synthesis of bacitracin is non-ribosomally catalyzed by a multi-enzyme complex BcrABC. Bacitracin has potent antibiotic activity against gram-positive bacteria. The inhibition of peptidoglycan biosynthesis is the best characterized bacterial effect of bacitracin. The bacitracin resistance of B. licheniformis is mediated by the ABC transporter Bcr which is composed of two identical BcrA ATP-binding subunits and one each of the integral membrane proteins, BcrB and BcrC. B. subtilis cells carrying bcr genes on high-copy number plasmids develop collateral detergent sensitivity, a similar phenomenon in human cells with overexpressed multi-drug resistance P-glycoprotein.
Pssm-ID: 213235 [Multi-domain] Cd Length: 208 Bit Score: 120.40 E-value: 3.09e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 4 ISLRGVQKAYGDGaPVIRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLSIGGKIMNDVPAAQRGVAMVFQ 83
Cdd:cd03268 1 LKTNDLTKTYGKK-RVLDDISLHVKKGEIYGFLGPNGAGKTTTMKIILGLIKPDSGEITFDGKSYQKNIEALRRIGALIE 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 84 SYALFPHMTVFENMAFGLKLAKTPKEEIDrkvrEAARVLQLEALLERRPKALSGGQRQRVAIGRAIVRQPGVFLFDEPLS 163
Cdd:cd03268 80 APGFYPNLTARENLRLLARLLGIRKKRID----EVLDVVGLKDSAKKKVKGFSLGMKQRLGIALALLGNPDLLILDEPTN 155
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 928002514 164 NLDATLRGQTRIEIARLHKQfaKASVVYVTHDQIEAMTLADKIVLLHAGK 213
Cdd:cd03268 156 GLDPDGIKELRELILSLRDQ--GITVLISSHLLSEIQKVADRIGIINKGK 203
|
|
| ectoine_ehuA |
TIGR03005 |
ectoine/hydroxyectoine ABC transporter, ATP-binding protein; Members of this family are the ... |
4-245 |
6.13e-32 |
|
ectoine/hydroxyectoine ABC transporter, ATP-binding protein; Members of this family are the ATP-binding protein of a conserved four gene ABC transporter operon found next to ectoine unilization operons and ectoine biosynthesis operons. Ectoine is a compatible solute that protects enzymes from high osmolarity. It is released by some species in response to hypoosmotic shock, and it is taken up by a number of bacteria as a compatible solute or for consumption. This family shows strong sequence similiarity to a number of amino acid ABC transporter ATP-binding proteins.
Pssm-ID: 132050 [Multi-domain] Cd Length: 252 Bit Score: 121.09 E-value: 6.13e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 4 ISLRGVQKAYGDgAPVIRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLSIGGKIMND--------VPAAQ 75
Cdd:TIGR03005 1 VRFSDVTKRFGI-LTVLDGLNFSVAAGEKVALIGPSGSGKSTILRILMTLEPIDEGQIQVEGEQLYHmpgrngplVPADE 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 76 RGVA-------MVFQSYALFPHMTVFENMAFGLKLAK-TPKEEIDRKVREAARVLQLEALLERRPKALSGGQRQRVAIGR 147
Cdd:TIGR03005 80 KHLRqmrnkigMVFQSFNLFPHKTVLDNVTEAPVLVLgMARAEAEKRAMELLDMVGLADKADHMPAQLSGGQQQRVAIAR 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 148 AIVRQPGVFLFDEPLSNLDATLRGQTRIEIARLHKQfAKASVVYVTHDQIEAMTLADKIVLLHAGKdterygsIAQIGAP 227
Cdd:TIGR03005 160 ALAMRPKVMLFDEVTSALDPELVGEVLNVIRRLASE-HDLTMLLVTHEMGFAREFADRVCFFDKGR-------IVEQGKP 231
|
250
....*....|....*...
gi 928002514 228 LELYHRPKSRFVAGFIGS 245
Cdd:TIGR03005 232 DEIFRQPKEERTREFLSK 249
|
|
| DppD |
COG0444 |
ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid ... |
4-235 |
6.33e-32 |
|
ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];
Pssm-ID: 440213 [Multi-domain] Cd Length: 320 Bit Score: 122.47 E-value: 6.33e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 4 ISLRGVQKAYGDGA---PVIRDVDLEIGENE-FCVfLGPSGCGKSTLLCMIAGLED---LTDGDLSIGGKIMNDVPAAQ- 75
Cdd:COG0444 2 LEVRNLKVYFPTRRgvvKAVDGVSFDVRRGEtLGL-VGESGSGKSTLARAILGLLPppgITSGEILFDGEDLLKLSEKEl 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 76 -----RGVAMVFQ-SY-ALFPHMTVFENMAFGLKL-AKTPKEEIDRKVREAARVLQL---EALLERRPKALSGGQRQRVA 144
Cdd:COG0444 81 rkirgREIQMIFQdPMtSLNPVMTVGDQIAEPLRIhGGLSKAEARERAIELLERVGLpdpERRLDRYPHELSGGMRQRVM 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 145 IGRAIVRQPGVFLFDEPLSNLDATLRGQtrI--EIARLHKQFaKASVVYVTHD-----QIeamtlADKIVLLHAGKdter 217
Cdd:COG0444 161 IARALALEPKLLIADEPTTALDVTIQAQ--IlnLLKDLQREL-GLAILFITHDlgvvaEI-----ADRVAVMYAGR---- 228
|
250
....*....|....*...
gi 928002514 218 ygsIAQIGAPLELYHRPK 235
Cdd:COG0444 229 ---IVEEGPVEELFENPR 243
|
|
| ABC_cobalt_CbiO_domain2 |
cd03226 |
Second domain of the ATP-binding cassette component of cobalt transport system; Domain II of ... |
13-213 |
9.27e-32 |
|
Second domain of the ATP-binding cassette component of cobalt transport system; Domain II of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota. The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed. The CbiMNQO family ABC transport system is involved in cobalt transport in association with the cobalamin (vitamin B12) biosynthetic pathways. Most cobalt (Cbi) transport systems possess a separate CbiN component, the cobalt-binding periplasmic protein, and they are encoded by the conserved gene cluster cbiMNQO. Both the CbiM and CbiQ proteins are integral cytoplasmic membrane proteins, and the CbiO protein has the linker peptide and the Walker A and B motifs commonly found in the ATPase components of the ABC-type transport systems.
Pssm-ID: 213193 [Multi-domain] Cd Length: 205 Bit Score: 118.90 E-value: 9.27e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 13 YGDGAPVIRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLSIGGKimnDVPAAQR--GVAMVFQS--YALF 88
Cdd:cd03226 9 YKKGTEILDDLSLDLYAGEIIALTGKNGAGKTTLAKILAGLIKESSGSILLNGK---PIKAKERrkSIGYVMQDvdYQLF 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 89 PHmTVFENMAFGLKLAKTPKEeidrKVREAARVLQLEALLERRPKALSGGQRQRVAIGRAIVRQPGVFLFDEPLSNLDat 168
Cdd:cd03226 86 TD-SVREELLLGLKELDAGNE----QAETVLKDLDLYALKERHPLSLSGGQKQRLAIAAALLSGKDLLIFDEPTSGLD-- 158
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 928002514 169 lRGQTRiEIARLHKQFAKA--SVVYVTHDQIEAMTLADKIVLLHAGK 213
Cdd:cd03226 159 -YKNME-RVGELIRELAAQgkAVIVITHDYEFLAKVCDRVLLLANGA 203
|
|
| CydD |
TIGR02857 |
thiol reductant ABC exporter, CydD subunit; The gene pair cydCD encodes an ABC-family ... |
3-209 |
1.06e-31 |
|
thiol reductant ABC exporter, CydD subunit; The gene pair cydCD encodes an ABC-family transporter in which each gene contains an N-terminal membrane-spanning domain (pfam00664) and a C-terminal ATP-binding domain (pfam00005). In E. coli these genes were discovered as mutants which caused the terminal heme-copper oxidase complex cytochrome bd to fail to assemble. Recent work has shown that the transporter is involved in export of redox-active thiol compounds such as cysteine and glutathione. The linkage to assembly of the cytochrome bd complex is further supported by the conserved operon structure found outside the gammaproteobacteria (cydABCD) containing both the transporter and oxidase genes components. The genes used as the seed members for this model are all either found in the gammproteobacterial context or the CydABCD context. All members of this family scoring above trusted at the time of its creation were from genomes which encode a cytochrome bd complex. Unfortunately, the gene symbol nomenclature adopted based on this operon in B. subtilis assigns cydC to the third gene in the operon where this gene is actually homologous to the E. coli cydD gene. We have chosen to name all homologs in this family in accordance with the precedence of publication of the E. coli name, CydD
Pssm-ID: 274323 [Multi-domain] Cd Length: 529 Bit Score: 125.48 E-value: 1.06e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 3 SISLRGVQKAYGDGAPVIRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLSIGGKIMNDVPAA--QRGVAM 80
Cdd:TIGR02857 321 SLEFSGVSVAYPGRRPALRPVSFTVPPGERVALVGPSGAGKSTLLNLLLGFVDPTEGSIAVNGVPLADADADswRDQIAW 400
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 81 VFQSYALFPHmTVFENMAFGLKLAktPKEEIDRKVREA-------ARVLQLEALLERRPKALSGGQRQRVAIGRAIVRQP 153
Cdd:TIGR02857 401 VPQHPFLFAG-TIAENIRLARPDA--SDAEIREALERAgldefvaALPQGLDTPIGEGGAGLSGGQAQRLALARAFLRDA 477
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 928002514 154 GVFLFDEPLSNLDATLRGQTRIEIARLhkqFAKASVVYVTHDqIEAMTLADKIVLL 209
Cdd:TIGR02857 478 PLLLLDEPTAHLDAETEAEVLEALRAL---AQGRTVLLVTHR-LALAALADRIVVL 529
|
|
| cbiO |
PRK13635 |
energy-coupling factor ABC transporter ATP-binding protein; |
4-231 |
1.17e-31 |
|
energy-coupling factor ABC transporter ATP-binding protein;
Pssm-ID: 184195 [Multi-domain] Cd Length: 279 Bit Score: 120.89 E-value: 1.17e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 4 ISLRGVQKAY-GDGAPVIRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLSIGGKIMND--VPAAQRGVAM 80
Cdd:PRK13635 6 IRVEHISFRYpDAATYALKDVSFSVYEGEWVAIVGHNGSGKSTLAKLLNGLLLPEAGTITVGGMVLSEetVWDVRRQVGM 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 81 VFQSY-ALFPHMTVFENMAFGLKLAKTPKEEIDRKVREAARVLQLEALLERRPKALSGGQRQRVAIGRAIVRQPGVFLFD 159
Cdd:PRK13635 86 VFQNPdNQFVGATVQDDVAFGLENIGVPREEMVERVDQALRQVGMEDFLNREPHRLSGGQKQRVAIAGVLALQPDIIILD 165
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 928002514 160 EPLSNLDATLRgQTRIEIARLHKQFAKASVVYVTHDQIEAMTlADKIVLLHAGKdterygsIAQIGAPLELY 231
Cdd:PRK13635 166 EATSMLDPRGR-REVLETVRQLKEQKGITVLSITHDLDEAAQ-ADRVIVMNKGE-------ILEEGTPEEIF 228
|
|
| ABC_TM1139_LivF_branched |
cd03224 |
ATP-binding cassette domain of branched-chain amino acid transporter; LivF (TM1139) is part of ... |
4-161 |
1.42e-31 |
|
ATP-binding cassette domain of branched-chain amino acid transporter; LivF (TM1139) is part of the LIV-I bacterial ABC-type two-component transport system that imports neutral, branched-chain amino acids. The E. coli branched-chain amino acid transporter comprises a heterodimer of ABC transporters (LivF and LivG), a heterodimer of six-helix TM domains (LivM and LivH), and one of two alternative soluble periplasmic substrate binding proteins (LivK or LivJ). ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules.
Pssm-ID: 213191 [Multi-domain] Cd Length: 222 Bit Score: 119.08 E-value: 1.42e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 4 ISLRGVQKAYGdGAPVIRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLSIGGKIMNDVPA---AQRGVAM 80
Cdd:cd03224 1 LEVENLNAGYG-KSQILFGVSLTVPEGEIVALLGRNGAGKTTLLKTIMGLLPPRSGSIRFDGRDITGLPPherARAGIGY 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 81 VFQSYALFPHMTVFENmafgLKLAKTPKEEIDRKvREAARVLQ----LEALLERRPKALSGGQRQRVAIGRAIVRQPGVF 156
Cdd:cd03224 80 VPEGRRIFPELTVEEN----LLLGAYARRRAKRK-ARLERVYElfprLKERRKQLAGTLSGGEQQMLAIARALMSRPKLL 154
|
....*
gi 928002514 157 LFDEP 161
Cdd:cd03224 155 LLDEP 159
|
|
| PRK14243 |
PRK14243 |
phosphate transporter ATP-binding protein; Provisional |
13-244 |
2.19e-31 |
|
phosphate transporter ATP-binding protein; Provisional
Pssm-ID: 184588 [Multi-domain] Cd Length: 264 Bit Score: 119.89 E-value: 2.19e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 13 YGDGAPViRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDL-----TDGDLSIGGKIMN----DVPAAQRGVAMVFQ 83
Cdd:PRK14243 20 YGSFLAV-KNVWLDIPKNQITAFIGPSGCGKSTILRCFNRLNDLipgfrVEGKVTFHGKNLYapdvDPVEVRRRIGMVFQ 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 84 SYALFPHmTVFENMAFGLKLAKTP---KEEIDRKVREAARVLQLEALLERRPKALSGGQRQRVAIGRAIVRQPGVFLFDE 160
Cdd:PRK14243 99 KPNPFPK-SIYDNIAYGARINGYKgdmDELVERSLRQAALWDEVKDKLKQSGLSLSGGQQQRLCIARAIAVQPEVILMDE 177
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 161 PLSNLD--ATLrgqtRIE--IARLHKQFakaSVVYVTHDQIEAMTLADKIVLLHAGKDTE--RYGSIAQIGAPLELYHRP 234
Cdd:PRK14243 178 PCSALDpiSTL----RIEelMHELKEQY---TIIIVTHNMQQAARVSDMTAFFNVELTEGggRYGYLVEFDRTEKIFNSP 250
|
250
....*....|....
gi 928002514 235 KSR----FVAGFIG 244
Cdd:PRK14243 251 QQQatrdYVSGRFG 264
|
|
| CeuD |
COG4604 |
ABC-type enterochelin transport system, ATPase component [Inorganic ion transport and ... |
4-230 |
5.75e-31 |
|
ABC-type enterochelin transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 443654 [Multi-domain] Cd Length: 252 Bit Score: 118.26 E-value: 5.75e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 4 ISLRGVQKAYGDgAPVIRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLSIGGKIMNDVPAAQ--RGVAMV 81
Cdd:COG4604 2 IEIKNVSKRYGG-KVVLDDVSLTIPKGGITALIGPNGAGKSTLLSMISRLLPPDSGEVLVDGLDVATTPSRElaKRLAIL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 82 FQSYALFPHMTVFENMAFGlklaKTP------KEEIDRKVREAARVLQLEALLERRPKALSGGQRQRVAIGRAIVRQPGV 155
Cdd:COG4604 81 RQENHINSRLTVRELVAFG----RFPyskgrlTAEDREIIDEAIAYLDLEDLADRYLDELSGGQRQRAFIAMVLAQDTDY 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 156 FLFDEPLSNLD--------ATLRgqtrieiaRLHKQFAKaSVVYVTHDQIEAMTLADKIVllhAGKDteryGSIAQIGAP 227
Cdd:COG4604 157 VLLDEPLNNLDmkhsvqmmKLLR--------RLADELGK-TVVIVLHDINFASCYADHIV---AMKD----GRVVAQGTP 220
|
...
gi 928002514 228 LEL 230
Cdd:COG4604 221 EEI 223
|
|
| lolD |
PRK11629 |
lipoprotein-releasing ABC transporter ATP-binding protein LolD; |
11-195 |
7.92e-31 |
|
lipoprotein-releasing ABC transporter ATP-binding protein LolD;
Pssm-ID: 183244 [Multi-domain] Cd Length: 233 Bit Score: 117.61 E-value: 7.92e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 11 KAYGDG---APVIRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLSIGGKIMNDVPAAQRG------VAMV 81
Cdd:PRK11629 13 KRYQEGsvqTDVLHNVSFSIGEGEMMAIVGSSGSGKSTLLHLLGGLDTPTSGDVIFNGQPMSKLSSAAKAelrnqkLGFI 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 82 FQSYALFPHMTVFENMAFGLKLAKTPKEEIDRKVREAARVLQLEALLERRPKALSGGQRQRVAIGRAIVRQPGVFLFDEP 161
Cdd:PRK11629 93 YQFHHLLPDFTALENVAMPLLIGKKKPAEINSRALEMLAAVGLEHRANHRPSELSGGERQRVAIARALVNNPRLVLADEP 172
|
170 180 190
....*....|....*....|....*....|....
gi 928002514 162 LSNLDATLRGQTRIEIARLHKQFAKASVVyVTHD 195
Cdd:PRK11629 173 TGNLDARNADSIFQLLGELNRLQGTAFLV-VTHD 205
|
|
| cbiO |
PRK13634 |
cobalt transporter ATP-binding subunit; Provisional |
4-234 |
2.35e-30 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 237454 [Multi-domain] Cd Length: 290 Bit Score: 117.81 E-value: 2.35e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 4 ISLRGVQKAYGDGAPVIR----DVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLSIG------GKIMNDVPA 73
Cdd:PRK13634 3 ITFQKVEHRYQYKTPFERralyDVNVSIPSGSYVAIIGHTGSGKSTLLQHLNGLLQPTSGTVTIGervitaGKKNKKLKP 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 74 AQRGVAMVFQsyalFPHMTVFE-----NMAFGLKLAKTPKEEIDRKVREAARVLQL-EALLERRPKALSGGQRQRVAIGR 147
Cdd:PRK13634 83 LRKKVGIVFQ----FPEHQLFEetvekDICFGPMNFGVSEEDAKQKAREMIELVGLpEELLARSPFELSGGQMRRVAIAG 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 148 AIVRQPGVFLFDEPLSNLDAtlRGqtRIEI----ARLHKQfAKASVVYVTHDQIEAMTLADKIVLLHAGKdterygsIAQ 223
Cdd:PRK13634 159 VLAMEPEVLVLDEPTAGLDP--KG--RKEMmemfYKLHKE-KGLTTVLVTHSMEDAARYADQIVVMHKGT-------VFL 226
|
250
....*....|.
gi 928002514 224 IGAPLELYHRP 234
Cdd:PRK13634 227 QGTPREIFADP 237
|
|
| ABC_DrrA |
cd03265 |
Daunorubicin/doxorubicin resistance ATP-binding protein; DrrA is the ATP-binding protein ... |
4-230 |
2.71e-30 |
|
Daunorubicin/doxorubicin resistance ATP-binding protein; DrrA is the ATP-binding protein component of a bacterial exporter complex that confers resistance to the antibiotics daunorubicin and doxorubicin. In addition to DrrA, the complex includes an integral membrane protein called DrrB. DrrA belongs to the ABC family of transporters and shares sequence and functional similarities with a protein found in cancer cells called P-glycoprotein. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region in addition to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213232 [Multi-domain] Cd Length: 220 Bit Score: 115.54 E-value: 2.71e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 4 ISLRGVQKAYGDGAPViRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLSIGG-KIMNDVPAAQRGVAMVF 82
Cdd:cd03265 1 IEVENLVKKYGDFEAV-RGVSFRVRRGEIFGLLGPNGAGKTTTIKMLTTLLKPTSGRATVAGhDVVREPREVRRRIGIVF 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 83 QSYALFPHMTVFENMAFGLKLAKTPKEEIDRKVREAARVLQLEALLERRPKALSGGQRQRVAIGRAIVRQPGVFLFDEPL 162
Cdd:cd03265 80 QDLSVDDELTGWENLYIHARLYGVPGAERRERIDELLDFVGLLEAADRLVKTYSGGMRRRLEIARSLVHRPEVLFLDEPT 159
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 928002514 163 SNLDATLRGQTRIEIARLHKQFAkASVVYVTHDQIEAMTLADKIVLLHAGKdterygsIAQIGAPLEL 230
Cdd:cd03265 160 IGLDPQTRAHVWEYIEKLKEEFG-MTILLTTHYMEEAEQLCDRVAIIDHGR-------IIAEGTPEEL 219
|
|
| ABC_Carb_Monos_I |
cd03216 |
First domain of the ATP-binding cassette component of monosaccharide transport system; This ... |
4-213 |
9.71e-30 |
|
First domain of the ATP-binding cassette component of monosaccharide transport system; This family represents the domain I of the carbohydrate uptake proteins that transport only monosaccharides (Monos). The Carb_Monos family is involved in the uptake of monosaccharides, such as pentoses (such as xylose, arabinose, and ribose) and hexoses (such as xylose, arabinose, and ribose), that cannot be broken down to simple sugars by hydrolysis. Pentoses include xylose, arabinose, and ribose. Important hexoses include glucose, galactose, and fructose. In members of the Carb_monos family, the single hydrophobic gene product forms a homodimer while the ABC protein represents a fusion of two nucleotide-binding domains. However, it is assumed that two copies of the ABC domains are present in the assembled transporter.
Pssm-ID: 213183 [Multi-domain] Cd Length: 163 Bit Score: 112.52 E-value: 9.71e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 4 ISLRGVQKAYGdGAPVIRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLSIGGK---IMNDVPAAQRGVAM 80
Cdd:cd03216 1 LELRGITKRFG-GVKALDGVSLSVRRGEVHALLGENGAGKSTLMKILSGLYKPDSGEILVDGKevsFASPRDARRAGIAM 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 81 VFQsyalfphmtvfenmafglklaktpkeeidrkvreaarvlqleallerrpkaLSGGQRQRVAIGRAIVRQPGVFLFDE 160
Cdd:cd03216 80 VYQ---------------------------------------------------LSVGERQMVEIARALARNARLLILDE 108
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 928002514 161 PLSNLDATLRGQTRIEIARLHKQfaKASVVYVTHDQIEAMTLADKIVLLHAGK 213
Cdd:cd03216 109 PTAALTPAEVERLFKVIRRLRAQ--GVAVIFISHRLDEVFEIADRVTVLRDGR 159
|
|
| PRK10619 |
PRK10619 |
histidine ABC transporter ATP-binding protein HisP; |
9-236 |
1.22e-29 |
|
histidine ABC transporter ATP-binding protein HisP;
Pssm-ID: 182592 [Multi-domain] Cd Length: 257 Bit Score: 115.07 E-value: 1.22e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 9 VQKAYGDgAPVIRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLSIGGKIMNDV--PAAQRGVA------- 79
Cdd:PRK10619 11 LHKRYGE-HEVLKGVSLQANAGDVISIIGSSGSGKSTFLRCINFLEKPSEGSIVVNGQTINLVrdKDGQLKVAdknqlrl 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 80 ------MVFQSYALFPHMTVFENMAFG----LKLAKTPKEEidRKVREAARVLQLEALLERRPKALSGGQRQRVAIGRAI 149
Cdd:PRK10619 90 lrtrltMVFQHFNLWSHMTVLENVMEApiqvLGLSKQEARE--RAVKYLAKVGIDERAQGKYPVHLSGGQQQRVSIARAL 167
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 150 VRQPGVFLFDEPLSNLDATLRGqtriEIARLHKQFAK--ASVVYVTHDQIEAMTLADKIVLLHAGKdterygsIAQIGAP 227
Cdd:PRK10619 168 AMEPEVLLFDEPTSALDPELVG----EVLRIMQQLAEegKTMVVVTHEMGFARHVSSHVIFLHQGK-------IEEEGAP 236
|
....*....
gi 928002514 228 LELYHRPKS 236
Cdd:PRK10619 237 EQLFGNPQS 245
|
|
| ABC_drug_resistance_like |
cd03264 |
ABC-type multidrug transport system, ATPase component; The biological function of this family ... |
4-213 |
1.69e-29 |
|
ABC-type multidrug transport system, ATPase component; The biological function of this family is not well characterized, but display ABC domains similar to members of ABCA subfamily. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213231 [Multi-domain] Cd Length: 211 Bit Score: 113.06 E-value: 1.69e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 4 ISLRGVQKAYGDGApVIRDVDLEIGENEFcVFLGPSGCGKSTLLCMIAGLEDLTDGDLSI-GGKIMNDVPAAQRGVAMVF 82
Cdd:cd03264 1 LQLENLTKRYGKKR-ALDGVSLTLGPGMY-GLLGPNGAGKTTLMRILATLTPPSSGTIRIdGQDVLKQPQKLRRRIGYLP 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 83 QSYALFPHMTVFENMAFGLKLAKTPKEEIDRKVREAARVLQLEALLERRPKALSGGQRQRVAIGRAIVRQPGVFLFDEPL 162
Cdd:cd03264 79 QEFGVYPNFTVREFLDYIAWLKGIPSKEVKARVDEVLELVNLGDRAKKKIGSLSGGMRRRVGIAQALVGDPSILIVDEPT 158
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 928002514 163 SNLDAtlrgQTRIEIARLHKQFAKASVVYV-TH--DQIEAMtlADKIVLLHAGK 213
Cdd:cd03264 159 AGLDP----EERIRFRNLLSELGEDRIVILsTHivEDVESL--CNQVAVLNKGK 206
|
|
| PRK14258 |
PRK14258 |
phosphate ABC transporter ATP-binding protein; Provisional |
13-234 |
3.15e-29 |
|
phosphate ABC transporter ATP-binding protein; Provisional
Pssm-ID: 184593 [Multi-domain] Cd Length: 261 Bit Score: 113.98 E-value: 3.15e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 13 YGDGAPVIRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLtDGDLSIGGKI----------MNDVPAAQRGVAMVF 82
Cdd:PRK14258 16 YYDTQKILEGVSMEIYQSKVTAIIGPSGCGKSTFLKCLNRMNEL-ESEVRVEGRVeffnqniyerRVNLNRLRRQVSMVH 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 83 QSYALFPhMTVFENMAFGLKLAK-TPKEEIDRKVREAARVLQL----EALLERRPKALSGGQRQRVAIGRAIVRQPGVFL 157
Cdd:PRK14258 95 PKPNLFP-MSVYDNVAYGVKIVGwRPKLEIDDIVESALKDADLwdeiKHKIHKSALDLSGGQQQRLCIARALAVKPKVLL 173
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 928002514 158 FDEPLSNLD--ATLRGQTRIEIARLHKQFakaSVVYVTHDQIEAMTLADKIVLLHAGKDteRYGSIAQIGAPLELYHRP 234
Cdd:PRK14258 174 MDEPCFGLDpiASMKVESLIQSLRLRSEL---TMVIVSHNLHQVSRLSDFTAFFKGNEN--RIGQLVEFGLTKKIFNSP 247
|
|
| NupO |
COG3845 |
ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and ... |
4-213 |
4.56e-29 |
|
ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and metabolism];
Pssm-ID: 443055 [Multi-domain] Cd Length: 504 Bit Score: 117.82 E-value: 4.56e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 4 ISLRGVQKAYGDgapVI--RDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLSIGGK---IMNDVPAAQRGV 78
Cdd:COG3845 6 LELRGITKRFGG---VVanDDVSLTVRPGEIHALLGENGAGKSTLMKILYGLYQPDSGEILIDGKpvrIRSPRDAIALGI 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 79 AMVFQSYALFPHMTVFENMAFGL---KLAKTPKEEIDRKVREAARVLQLEALLERRPKALSGGQRQRVAIGRAIVRQPGV 155
Cdd:COG3845 83 GMVHQHFMLVPNLTVAENIVLGLeptKGGRLDRKAARARIRELSERYGLDVDPDAKVEDLSVGEQQRVEILKALYRGARI 162
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 928002514 156 FLFDEPLSNLdatlrgqTRIEIARLH---KQFAKA--SVVYVTHDQIEAMTLADKIVLLHAGK 213
Cdd:COG3845 163 LILDEPTAVL-------TPQEADELFeilRRLAAEgkSIIFITHKLREVMAIADRVTVLRRGK 218
|
|
| ABCC_Glucan_exporter_like |
cd03254 |
ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Glucan ... |
4-230 |
5.46e-29 |
|
ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Glucan exporter ATP-binding protein. In A. tumefaciens cyclic beta-1, 2-glucan must be transported into the periplasmic space to exert its action as a virulence factor. This subfamily belongs to the MRP-like family and is involved in drug, peptide, and lipid export. The MRP-like family, similar to all ABC proteins, have a common four-domain core structure constituted by two membrane-spanning domains each composed of six transmembrane (TM) helices and two nucleotide-binding domains (NBD). ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213221 [Multi-domain] Cd Length: 229 Bit Score: 112.32 E-value: 5.46e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 4 ISLRGVQKAYGDGAPVIRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLSIGGKIMNDVPAAQ--RGVAMV 81
Cdd:cd03254 3 IEFENVNFSYDEKKPVLKDINFSIKPGETVAIVGPTGAGKTTLINLLMRFYDPQKGQILIDGIDIRDISRKSlrSMIGVV 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 82 FQSYALFPHmTVFENMAFGLKLAKtpkeeiDRKVREAARVLQLEALLERRPKA-----------LSGGQRQRVAIGRAIV 150
Cdd:cd03254 83 LQDTFLFSG-TIMENIRLGRPNAT------DEEVIEAAKEAGAHDFIMKLPNGydtvlgenggnLSQGERQLLAIARAML 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 151 RQPGVFLFDEPLSNLD------------ATLRGQTRIEIA-RLhkqfakASVVYvthdqieamtlADKIVLLHAGKdter 217
Cdd:cd03254 156 RDPKILILDEATSNIDtetekliqealeKLMKGRTSIIIAhRL------STIKN-----------ADKILVLDDGK---- 214
|
250
....*....|...
gi 928002514 218 ygsIAQIGAPLEL 230
Cdd:cd03254 215 ---IIEEGTHDEL 224
|
|
| PRK10908 |
PRK10908 |
cell division ATP-binding protein FtsE; |
4-195 |
6.15e-29 |
|
cell division ATP-binding protein FtsE;
Pssm-ID: 182829 [Multi-domain] Cd Length: 222 Bit Score: 112.28 E-value: 6.15e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 4 ISLRGVQKAYGDGAPVIRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLSIGGKIMN-----DVPAAQRGV 78
Cdd:PRK10908 2 IRFEHVSKAYLGGRQALQGVTFHMRPGEMAFLTGHSGAGKSTLLKLICGIERPSAGKIWFSGHDITrlknrEVPFLRRQI 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 79 AMVFQSYALFPHMTVFENMAFGLKLAKTPKEEIDRKVREAARVLQLEALLERRPKALSGGQRQRVAIGRAIVRQPGVFLF 158
Cdd:PRK10908 82 GMIFQDHHLLMDRTVYDNVAIPLIIAGASGDDIRRRVSAALDKVGLLDKAKNFPIQLSGGEQQRVGIARAVVNKPAVLLA 161
|
170 180 190
....*....|....*....|....*....|....*....
gi 928002514 159 DEPLSNLDATLRGqtriEIARLHKQFAK--ASVVYVTHD 195
Cdd:PRK10908 162 DEPTGNLDDALSE----GILRLFEEFNRvgVTVLMATHD 196
|
|
| nickel_nikE |
TIGR02769 |
nickel import ATP-binding protein NikE; This family represents the NikE subunit of a ... |
4-216 |
6.80e-29 |
|
nickel import ATP-binding protein NikE; This family represents the NikE subunit of a multisubunit nickel import ABC transporter complex. Nickel, once imported, may be used in urease and in certain classes of hydrogenase and superoxide dismutase. [Transport and binding proteins, Cations and iron carrying compounds]
Pssm-ID: 131816 [Multi-domain] Cd Length: 265 Bit Score: 112.98 E-value: 6.80e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 4 ISLRGVQKAYGDG--------APVIRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLSIGGKIMNDVP--- 72
Cdd:TIGR02769 3 LEVRDVTHTYRTGglfgakqrAPVLTNVSLSIEEGETVGLLGRSGCGKSTLARLLLGLEKPAQGTVSFRGQDLYQLDrkq 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 73 --AAQRGVAMVFQ-SYALF-PHMTVFENMAFGLK-LAKTPKEEIDRKVREAARVLQLEA-LLERRPKALSGGQRQRVAIG 146
Cdd:TIGR02769 83 rrAFRRDVQLVFQdSPSAVnPRMTVRQIIGEPLRhLTSLDESEQKARIAELLDMVGLRSeDADKLPRQLSGGQLQRINIA 162
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 147 RAIVRQPGVFLFDEPLSNLDATLRGQTRIEIARLHKQFAKAsVVYVTHDQIEAMTLADKIVLLHAGKDTE 216
Cdd:TIGR02769 163 RALAVKPKLIVLDEAVSNLDMVLQAVILELLRKLQQAFGTA-YLFITHDLRLVQSFCQRVAVMDKGQIVE 231
|
|
| LivF |
COG0410 |
ABC-type branched-chain amino acid transport system, ATPase component LivF [Amino acid ... |
1-161 |
1.35e-28 |
|
ABC-type branched-chain amino acid transport system, ATPase component LivF [Amino acid transport and metabolism];
Pssm-ID: 440179 [Multi-domain] Cd Length: 236 Bit Score: 111.61 E-value: 1.35e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 1 MASISLRGVQKAYGDgAPVIRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLSIGGKIMNDVPA---AQRG 77
Cdd:COG0410 1 MPMLEVENLHAGYGG-IHVLHGVSLEVEEGEIVALLGRNGAGKTTLLKAISGLLPPRSGSIRFDGEDITGLPPhriARLG 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 78 VAMVFQSYALFPHMTVFENMAFGLKLAKtPKEEIDRKVreaARVLQL-EALLERRPK---ALSGGQRQRVAIGRAIVRQP 153
Cdd:COG0410 80 IGYVPEGRRIFPSLTVEENLLLGAYARR-DRAEVRADL---ERVYELfPRLKERRRQragTLSGGEQQMLAIGRALMSRP 155
|
....*...
gi 928002514 154 GVFLFDEP 161
Cdd:COG0410 156 KLLLLDEP 163
|
|
| cbiO |
PRK13644 |
energy-coupling factor transporter ATPase; |
4-213 |
1.98e-28 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 106587 [Multi-domain] Cd Length: 274 Bit Score: 112.00 E-value: 1.98e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 4 ISLRGVQKAYGDGAPVIRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLSIGGKIMND---VPAAQRGVAM 80
Cdd:PRK13644 2 IRLENVSYSYPDGTPALENINLVIKKGEYIGIIGKNGSGKSTLALHLNGLLRPQKGKVLVSGIDTGDfskLQGIRKLVGI 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 81 VFQS-YALFPHMTVFENMAFGLKLAKTPKEEIDRKVREAARVLQLEALLERRPKALSGGQRQRVAIGRAIVRQPGVFLFD 159
Cdd:PRK13644 82 VFQNpETQFVGRTVEEDLAFGPENLCLPPIEIRKRVDRALAEIGLEKYRHRSPKTLSGGQGQCVALAGILTMEPECLIFD 161
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 928002514 160 EPLSNLDATlRGQTRIE-IARLHKQfaKASVVYVTHDqIEAMTLADKIVLLHAGK 213
Cdd:PRK13644 162 EVTSMLDPD-SGIAVLErIKKLHEK--GKTIVYITHN-LEELHDADRIIVMDRGK 212
|
|
| PRK14246 |
PRK14246 |
phosphate ABC transporter ATP-binding protein; Provisional |
13-243 |
2.69e-28 |
|
phosphate ABC transporter ATP-binding protein; Provisional
Pssm-ID: 172734 [Multi-domain] Cd Length: 257 Bit Score: 111.29 E-value: 2.69e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 13 YGDGAPVIRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLSIGGKIMN--------DVPAAQRGVAMVFQS 84
Cdd:PRK14246 19 YINDKAILKDITIKIPNNSIFGIMGPSGSGKSTLLKVLNRLIEIYDSKIKVDGKVLYfgkdifqiDAIKLRKEVGMVFQQ 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 85 YALFPHMTVFENMAFGLKL-AKTPKEEIDRKVREAARVLQLEALLERR----PKALSGGQRQRVAIGRAIVRQPGVFLFD 159
Cdd:PRK14246 99 PNPFPHLSIYDNIAYPLKShGIKEKREIKKIVEECLRKVGLWKEVYDRlnspASQLSGGQQQRLTIARALALKPKVLLMD 178
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 160 EPLSNLDATLRGQTRIEIARLHKQFAkasVVYVTHDQIEAMTLADKIVLLHAGKdterygsIAQIGAPLELYHRPKSRFV 239
Cdd:PRK14246 179 EPTSMIDIVNSQAIEKLITELKNEIA---IVIVSHNPQQVARVADYVAFLYNGE-------LVEWGSSNEIFTSPKNELT 248
|
....
gi 928002514 240 AGFI 243
Cdd:PRK14246 249 EKYV 252
|
|
| ModF |
COG1119 |
ABC-type molybdenum transport system, ATPase component ModF/photorepair protein PhrA ... |
4-233 |
3.28e-28 |
|
ABC-type molybdenum transport system, ATPase component ModF/photorepair protein PhrA [Inorganic ion transport and metabolism];
Pssm-ID: 440736 [Multi-domain] Cd Length: 250 Bit Score: 110.94 E-value: 3.28e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 4 ISLRGVQKAYGdGAPVIRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDG-DLSIGGKimndvpaaQRGVAMVF 82
Cdd:COG1119 4 LELRNVTVRRG-GKTILDDISWTVKPGEHWAILGPNGAGKSTLLSLITGDLPPTYGnDVRLFGE--------RRGGEDVW 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 83 Q--------SYALF----PHMTVFENMAFGLK----LAKTPKEEIDRKVREAARVLQLEALLERRPKALSGGQRQRVAIG 146
Cdd:COG1119 75 ElrkriglvSPALQlrfpRDETVLDVVLSGFFdsigLYREPTDEQRERARELLELLGLAHLADRPFGTLSQGEQRRVLIA 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 147 RAIVRQPGVFLFDEPLSNLDATLRGQTRIEIARLHKQFAKAsVVYVTH---DQIEAMTladKIVLLHAGKDTERyGSIAQ 223
Cdd:COG1119 155 RALVKDPELLILDEPTAGLDLGARELLLALLDKLAAEGAPT-LVLVTHhveEIPPGIT---HVLLLKDGRVVAA-GPKEE 229
|
250 260
....*....|....*....|
gi 928002514 224 I----------GAPLELYHR 233
Cdd:COG1119 230 VltsenlseafGLPVEVERR 249
|
|
| type_I_sec_LssB |
TIGR03375 |
type I secretion system ATPase, LssB family; Type I protein secretion is a system in some ... |
3-213 |
3.49e-28 |
|
type I secretion system ATPase, LssB family; Type I protein secretion is a system in some Gram-negative bacteria to export proteins (often proteases) across both inner and outer membranes to the extracellular medium. This is one of three proteins of the type I secretion apparatus. Targeted proteins are not cleaved at the N-terminus, but rather carry signals located toward the extreme C-terminus to direct type I secretion. This model is related to models TIGR01842 and TIGR01846, and to bacteriocin ABC transporters that cleave their substrates during export. [Protein fate, Protein and peptide secretion and trafficking, Cellular processes, Pathogenesis]
Pssm-ID: 274550 [Multi-domain] Cd Length: 694 Bit Score: 116.12 E-value: 3.49e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 3 SISLRGVQKAY-GDGAPVIRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLSIGGKIMNDVPAA--QRGVA 79
Cdd:TIGR03375 463 EIEFRNVSFAYpGQETPALDNVSLTIRPGEKVAIIGRIGSGKSTLLKLLLGLYQPTEGSVLLDGVDIRQIDPAdlRRNIG 542
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 80 MVFQSYALFpHMTVFENMAFGLKLAKtpkeeiDRKVREAARVLQLEALLERRPK-----------ALSGGQRQRVAIGRA 148
Cdd:TIGR03375 543 YVPQDPRLF-YGTLRDNIALGAPYAD------DEEILRAAELAGVTEFVRRHPDgldmqigergrSLSGGQRQAVALARA 615
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 928002514 149 IVRQPGVFLFDEPLSNLDATLRGQTrieIARLHKQFAKASVVYVTHdQIEAMTLADKIVLLHAGK 213
Cdd:TIGR03375 616 LLRDPPILLLDEPTSAMDNRSEERF---KDRLKRWLAGKTLVLVTH-RTSLLDLVDRIIVMDNGR 676
|
|
| ABCC_bacteriocin_exporters |
cd03245 |
ATP-binding cassette domain of bacteriocin exporters, subfamily C; Many non-lantibiotic ... |
3-213 |
5.53e-28 |
|
ATP-binding cassette domain of bacteriocin exporters, subfamily C; Many non-lantibiotic bacteriocins of lactic acid bacteria are produced as precursors which have N-terminal leader peptides that share similarities in amino acid sequence and contain a conserved processing site of two glycine residues in positions -1 and -2. A dedicated ATP-binding cassette (ABC) transporter is responsible for the proteolytic cleavage of the leader peptides and subsequent translocation of the bacteriocins across the cytoplasmic membrane.
Pssm-ID: 213212 [Multi-domain] Cd Length: 220 Bit Score: 109.22 E-value: 5.53e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 3 SISLRGVQKAY-GDGAPVIRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLSIGGKIMNDVPAA--QRGVA 79
Cdd:cd03245 2 RIEFRNVSFSYpNQEIPALDNVSLTIRAGEKVAIIGRVGSGKSTLLKLLAGLYKPTSGSVLLDGTDIRQLDPAdlRRNIG 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 80 MVFQSYALFpHMTVFENMAFGLKLAKtpkeeiDRKVREAARVLQLEALLERRPK-----------ALSGGQRQRVAIGRA 148
Cdd:cd03245 82 YVPQDVTLF-YGTLRDNITLGAPLAD------DERILRAAELAGVTDFVNKHPNgldlqigergrGLSGGQRQAVALARA 154
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 928002514 149 IVRQPGVFLFDEPLSNLDatLRGQTRIeIARLHKQFAKASVVYVTHdQIEAMTLADKIVLLHAGK 213
Cdd:cd03245 155 LLNDPPILLLDEPTSAMD--MNSEERL-KERLRQLLGDKTLIIITH-RPSLLDLVDRIIVMDSGR 215
|
|
| nikE |
PRK10419 |
nickel ABC transporter ATP-binding protein NikE; |
1-237 |
5.65e-28 |
|
nickel ABC transporter ATP-binding protein NikE;
Pssm-ID: 236689 [Multi-domain] Cd Length: 268 Bit Score: 110.55 E-value: 5.65e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 1 MASISLRGVQKAYGDGA--------PVIRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLSIGGKIMN--- 69
Cdd:PRK10419 1 MTLLNVSGLSHHYAHGGlsgkhqhqTVLNNVSLSLKSGETVALLGRSGCGKSTLARLLVGLESPSQGNVSWRGEPLAkln 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 70 --DVPAAQRGVAMVFQSY--ALFPHMTVFENMAFGLK-LAKTPKEEIDRKVREAARVLQL-EALLERRPKALSGGQRQRV 143
Cdd:PRK10419 81 raQRKAFRRDIQMVFQDSisAVNPRKTVREIIREPLRhLLSLDKAERLARASEMLRAVDLdDSVLDKRPPQLSGGQLQRV 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 144 AIGRAIVRQPGVFLFDEPLSNLDATLRGQTRIEIARLHKQFAKAsVVYVTHDQIEAMTLADKIVLLHAGKDTERygsiAQ 223
Cdd:PRK10419 161 CLARALAVEPKLLILDEAVSNLDLVLQAGVIRLLKKLQQQFGTA-CLFITHDLRLVERFCQRVMVMDNGQIVET----QP 235
|
250
....*....|....
gi 928002514 224 IGAPLELYHrPKSR 237
Cdd:PRK10419 236 VGDKLTFSS-PAGR 248
|
|
| ABCC_Protease_Secretion |
cd03246 |
ATP-binding cassette domain of PrtD, subfamily C; This family represents the ABC component of ... |
4-213 |
7.05e-28 |
|
ATP-binding cassette domain of PrtD, subfamily C; This family represents the ABC component of the protease secretion system PrtD, a 60-kDa integral membrane protein sharing 37% identity with HlyB, the ABC component of the alpha-hemolysin secretion pathway, in the C-terminal domain. They export degradative enzymes by using a type I protein secretion system and lack an N-terminal signal peptide, but contain a C-terminal secretion signal. The Type I secretion apparatus is made up of three components, an ABC transporter, a membrane fusion protein (MFP), and an outer membrane protein (OMP). For the HlyA transporter complex, HlyB (ABC transporter) and HlyD (MFP) reside in the inner membrane of E. coli. The OMP component is TolC, which is thought to interact with the MFP to form a continuous channel across the periplasm from the cytoplasm to the exterior. HlyB belongs to the family of ABC transporters, which are ubiquitous, ATP-dependent transmembrane pumps or channels. The spectrum of transport substrates ranges from inorganic ions, nutrients such as amino acids, sugars, or peptides, hydrophobic drugs, to large polypeptides, such as HlyA.
Pssm-ID: 213213 [Multi-domain] Cd Length: 173 Bit Score: 107.69 E-value: 7.05e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 4 ISLRGVQKAYGDGA-PVIRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLSIGGKIMNDVPAAQRG--VAM 80
Cdd:cd03246 1 LEVENVSFRYPGAEpPVLRNVSFSIEPGESLAIIGPSGSGKSTLARLILGLLRPTSGRVRLDGADISQWDPNELGdhVGY 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 81 VFQSYALFPHmTVFENMafglklaktpkeeidrkvreaarvlqleallerrpkaLSGGQRQRVAIGRAIVRQPGVFLFDE 160
Cdd:cd03246 81 LPQDDELFSG-SIAENI-------------------------------------LSGGQRQRLGLARALYGNPRILVLDE 122
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 928002514 161 PLSNLDATlrGQTRIEIARLHKQFAKASVVYVTHdQIEAMTLADKIVLLHAGK 213
Cdd:cd03246 123 PNSHLDVE--GERALNQAIAALKAAGATRIVIAH-RPETLASADRILVLEDGR 172
|
|
| ABCC_MsbA |
cd03251 |
ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; ... |
4-217 |
1.20e-27 |
|
ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; MsbA is an essential ABC transporter, closely related to eukaryotic MDR proteins. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213218 [Multi-domain] Cd Length: 234 Bit Score: 108.86 E-value: 1.20e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 4 ISLRGVQKAY-GDGAPVIRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLSIGGKIMNDVPAAQ--RGVAM 80
Cdd:cd03251 1 VEFKNVTFRYpGDGPPVLRDISLDIPAGETVALVGPSGSGKSTLVNLIPRFYDVDSGRILIDGHDVRDYTLASlrRQIGL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 81 VFQSYALFpHMTVFENMAFGlklaktpKEEIDRK-VREAARVLQLEALLERRPKA-----------LSGGQRQRVAIGRA 148
Cdd:cd03251 81 VSQDVFLF-NDTVAENIAYG-------RPGATREeVEEAARAANAHEFIMELPEGydtvigergvkLSGGQRQRIAIARA 152
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 928002514 149 IVRQPGVFLFDEPLSNLDATLRGQTRIEIARLhkqfAKASVVYVTHDQIEAMTLADKIVLLHAGKDTER 217
Cdd:cd03251 153 LLKDPPILILDEATSALDTESERLVQAALERL----MKNRTTFVIAHRLSTIENADRIVVLEDGKIVER 217
|
|
| ABC_putative_ATPase |
cd03269 |
ATP-binding cassette domain of an uncharacterized transporter; This subgroup is related to the ... |
4-213 |
1.34e-27 |
|
ATP-binding cassette domain of an uncharacterized transporter; This subgroup is related to the subfamily A transporters involved in drug resistance, nodulation, lipid transport, and bacteriocin and lantibiotic immunity. In eubacteria and archaea, the typical organization consists of one ABC and one or two integral membranes. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region in addition to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213236 [Multi-domain] Cd Length: 210 Bit Score: 108.14 E-value: 1.34e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 4 ISLRGVQKAYGDgAPVIRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLSIGGKIMNdvPAAQRGVAMVFQ 83
Cdd:cd03269 1 LEVENVTKRFGR-VTALDDISFSVEKGEIFGLLGPNGAGKTTTIRMILGIILPDSGEVLFDGKPLD--IAARNRIGYLPE 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 84 SYALFPHMTVFENMAFGLKLAKTPKEEIDRKVREAARVLQLEALLERRPKALSGGQRQRVAIGRAIVRQPGVFLFDEPLS 163
Cdd:cd03269 78 ERGLYPKMKVIDQLVYLAQLKGLKKEEARRRIDEWLERLELSEYANKRVEELSKGNQQKVQFIAAVIHDPELLILDEPFS 157
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 928002514 164 NLDATLRGQTRIEIARLhkQFAKASVVYVTH--DQIEAMtlADKIVLLHAGK 213
Cdd:cd03269 158 GLDPVNVELLKDVIREL--ARAGKTVILSTHqmELVEEL--CDRVLLLNKGR 205
|
|
| AztA |
NF040873 |
zinc ABC transporter ATP-binding protein AztA; |
15-209 |
1.55e-27 |
|
zinc ABC transporter ATP-binding protein AztA;
Pssm-ID: 468810 [Multi-domain] Cd Length: 191 Bit Score: 107.32 E-value: 1.55e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 15 DGAPVIRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLSIGGKimndvpaaqRGVAMVFQSYAL---FPhM 91
Cdd:NF040873 3 GGRPVLHGVDLTIPAGSLTAVVGPNGSGKSTLLKVLAGVLRPTSGTVRRAGG---------ARVAYVPQRSEVpdsLP-L 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 92 TVFENMAFGL----KLAKTPKEEIDRKVREAARVLQLEALLERRPKALSGGQRQRVAIGRAIVRQPGVFLFDEPLSNLDA 167
Cdd:NF040873 73 TVRDLVAMGRwarrGLWRRLTRDDRAAVDDALERVGLADLAGRQLGELSGGQRQRALLAQGLAQEADLLLLDEPTTGLDA 152
|
170 180 190 200
....*....|....*....|....*....|....*....|..
gi 928002514 168 TLRGQTRIEIARLHKQfaKASVVYVTHDqIEAMTLADKIVLL 209
Cdd:NF040873 153 ESRERIIALLAEEHAR--GATVVVVTHD-LELVRRADPCVLL 191
|
|
| AppF |
COG4608 |
ABC-type oligopeptide transport system, ATPase component [Amino acid transport and metabolism]; ... |
22-172 |
2.23e-27 |
|
ABC-type oligopeptide transport system, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 443658 [Multi-domain] Cd Length: 329 Bit Score: 110.21 E-value: 2.23e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 22 DVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLSIGGKIMNDVPAAQ-----RGVAMVFQ-SYA-LFPHMTVF 94
Cdd:COG4608 36 GVSFDIRRGETLGLVGESGCGKSTLGRLLLRLEEPTSGEILFDGQDITGLSGRElrplrRRMQMVFQdPYAsLNPRMTVG 115
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 95 ENMAFGLKLAK-TPKEEIDRKVREAARVLQLEA-LLERRPKALSGGQRQRVAIGRAIVRQPGVFLFDEPLSNLDATLRGQ 172
Cdd:COG4608 116 DIIAEPLRIHGlASKAERRERVAELLELVGLRPeHADRYPHEFSGGQRQRIGIARALALNPKLIVCDEPVSALDVSIQAQ 195
|
|
| PhnK |
COG1101 |
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ... |
4-213 |
2.60e-27 |
|
ABC-type uncharacterized transport system, ATPase component [General function prediction only];
Pssm-ID: 440718 [Multi-domain] Cd Length: 264 Bit Score: 108.63 E-value: 2.60e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 4 ISLRGVQKAYGDGAP----VIRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLSIGGKIMNDVPAAQRG-- 77
Cdd:COG1101 2 LELKNLSKTFNPGTVnekrALDGLNLTIEEGDFVTVIGSNGAGKSTLLNAIAGSLPPDSGSILIDGKDVTKLPEYKRAky 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 78 VAMVFQSYAL--FPHMTVFENMA--------FGLKLAKTpKEEIDRkVREAARVLQLEalLERRPKA----LSGGQRQRV 143
Cdd:COG1101 82 IGRVFQDPMMgtAPSMTIEENLAlayrrgkrRGLRRGLT-KKRREL-FRELLATLGLG--LENRLDTkvglLSGGQRQAL 157
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 928002514 144 AIGRAIVRQPGVFLFDEPLSNLDAtlrgQTRIEIARLHKQFAKA---SVVYVTHDQIEAMTLADKIVLLHAGK 213
Cdd:COG1101 158 SLLMATLTKPKLLLLDEHTAALDP----KTAALVLELTEKIVEEnnlTTLMVTHNMEQALDYGNRLIMMHEGR 226
|
|
| PRK10247 |
PRK10247 |
putative ABC transporter ATP-binding protein YbbL; Provisional |
15-216 |
1.24e-26 |
|
putative ABC transporter ATP-binding protein YbbL; Provisional
Pssm-ID: 182331 [Multi-domain] Cd Length: 225 Bit Score: 105.95 E-value: 1.24e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 15 DGAPVIRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLSIGGKIMNDVP--AAQRGVAMVFQSYALFPHmT 92
Cdd:PRK10247 18 GDAKILNNISFSLRAGEFKLITGPSGCGKSTLLKIVASLISPTSGTLLFEGEDISTLKpeIYRQQVSYCAQTPTLFGD-T 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 93 VFENMAFGLKLAKTPKEEiDRKVREAARVLQLEALLERRPKALSGGQRQRVAIGRAIVRQPGVFLFDEPLSNLDATLRGQ 172
Cdd:PRK10247 97 VYDNLIFPWQIRNQQPDP-AIFLDDLERFALPDTILTKNIAELSGGEKQRISLIRNLQFMPKVLLLDEITSALDESNKHN 175
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 928002514 173 TRIEIARLHKQfAKASVVYVTHDQIEaMTLADKIVLL--HAGKDTE 216
Cdd:PRK10247 176 VNEIIHRYVRE-QNIAVLWVTHDKDE-INHADKVITLqpHAGEMQE 219
|
|
| COG4559 |
COG4559 |
ABC-type hemin transport system, ATPase component [Inorganic ion transport and metabolism]; |
16-213 |
3.86e-26 |
|
ABC-type hemin transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 443620 [Multi-domain] Cd Length: 258 Bit Score: 105.20 E-value: 3.86e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 16 GAPVIRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLSIGGKIMNDVP----AAQRGVamVFQSYAL-FPh 90
Cdd:COG4559 13 GRTLLDDVSLTLRPGELTAIIGPNGAGKSTLLKLLTGELTPSSGEVRLNGRPLAAWSpwelARRRAV--LPQHSSLaFP- 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 91 MTVFENMAFGLKLAKTPKEEIDRKVREAARVLQLEALLERRPKALSGGQRQRVAIGRAI------VRQPGVFLF-DEPLS 163
Cdd:COG4559 90 FTVEEVVALGRAPHGSSAAQDRQIVREALALVGLAHLAGRSYQTLSGGEQQRVQLARVLaqlwepVDGGPRWLFlDEPTS 169
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 928002514 164 NLDatLRGQtrIEIARLHKQFAKA--SVVYVTHDQIEAMTLADKIVLLHAGK 213
Cdd:COG4559 170 ALD--LAHQ--HAVLRLARQLARRggGVVAVLHDLNLAAQYADRILLLHQGR 217
|
|
| cbiO |
PRK13647 |
cobalt transporter ATP-binding subunit; Provisional |
13-213 |
4.22e-26 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 237457 [Multi-domain] Cd Length: 274 Bit Score: 105.59 E-value: 4.22e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 13 YGDGAPVIRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLSIGGKIMNdvPAAQR----GVAMVFQSY--A 86
Cdd:PRK13647 14 YKDGTKALKGLSLSIPEGSKTALLGPNGAGKSTLLLHLNGIYLPQRGRVKVMGREVN--AENEKwvrsKVGLVFQDPddQ 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 87 LFPhMTVFENMAFGLKLAKTPKEEIDRKVREAARVLQLEALLERRPKALSGGQRQRVAIGRAIVRQPGVFLFDEPLSNLD 166
Cdd:PRK13647 92 VFS-STVWDDVAFGPVNMGLDKDEVERRVEEALKAVRMWDFRDKPPYHLSYGQKKRVAIAGVLAMDPDVIVLDEPMAYLD 170
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 928002514 167 AtlRGQ-TRIEI-ARLHKQfaKASVVYVTHDQIEAMTLADKIVLLHAGK 213
Cdd:PRK13647 171 P--RGQeTLMEIlDRLHNQ--GKTVIVATHDVDLAAEWADQVIVLKEGR 215
|
|
| urea_trans_UrtE |
TIGR03410 |
urea ABC transporter, ATP-binding protein UrtE; Members of this protein family are ABC ... |
5-161 |
5.38e-26 |
|
urea ABC transporter, ATP-binding protein UrtE; Members of this protein family are ABC transporter ATP-binding subunits associated with urea transport and metabolism. This protein is found in a conserved five-gene transport operon typically found adjacent to urease genes. It was shown in Cyanobacteria that disruption leads to the loss of high-affinity urea transport activity. [Transport and binding proteins, Amino acids, peptides and amines]
Pssm-ID: 274567 [Multi-domain] Cd Length: 230 Bit Score: 104.14 E-value: 5.38e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 5 SLRGVQKAYGdGAPVIRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLSIGGKIMNDVPAAQR---GVAMV 81
Cdd:TIGR03410 2 EVSNLNVYYG-QSHILRGVSLEVPKGEVTCVLGRNGVGKTTLLKTLMGLLPVKSGSIRLDGEDITKLPPHERaraGIAYV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 82 FQSYALFPHMTVFENMAFGLKLAKTPKEEIDRKVREAARVLQleALLERRPKALSGGQRQRVAIGRAIVRQPGVFLFDEP 161
Cdd:TIGR03410 81 PQGREIFPRLTVEENLLTGLAALPRRSRKIPDEIYELFPVLK--EMLGRRGGDLSGGQQQQLAIARALVTRPKLLLLDEP 158
|
|
| PRK15079 |
PRK15079 |
oligopeptide ABC transporter ATP-binding protein OppF; Provisional |
22-235 |
6.88e-26 |
|
oligopeptide ABC transporter ATP-binding protein OppF; Provisional
Pssm-ID: 185037 [Multi-domain] Cd Length: 331 Bit Score: 106.33 E-value: 6.88e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 22 DVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLSIGGKIMNDVPAAQR-----GVAMVFQS--YALFPHMTVF 94
Cdd:PRK15079 39 GVTLRLYEGETLGVVGESGCGKSTFARAIIGLVKATDGEVAWLGKDLLGMKDDEWravrsDIQMIFQDplASLNPRMTIG 118
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 95 ENMAFGLKL--AKTPKEEIDRKVREA-ARVLQLEALLERRPKALSGGQRQRVAIGRAIVRQPGVFLFDEPLSNLDATLRG 171
Cdd:PRK15079 119 EIIAEPLRTyhPKLSRQEVKDRVKAMmLKVGLLPNLINRYPHEFSGGQCQRIGIARALILEPKLIICDEPVSALDVSIQA 198
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 928002514 172 QtrieIARLHKQFAKA---SVVYVTHDQIEAMTLADKIVLLHAGKDTErygsiaqIGAPLELYHRPK 235
Cdd:PRK15079 199 Q----VVNLLQQLQREmglSLIFIAHDLAVVKHISDRVLVMYLGHAVE-------LGTYDEVYHNPL 254
|
|
| cbiO |
PRK13639 |
cobalt transporter ATP-binding subunit; Provisional |
4-235 |
2.37e-25 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 184199 [Multi-domain] Cd Length: 275 Bit Score: 103.62 E-value: 2.37e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 4 ISLRGVQKAYGDGAPVIRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLSIGGKIMN----DVPAAQRGVA 79
Cdd:PRK13639 2 LETRDLKYSYPDGTEALKGINFKAEKGEMVALLGPNGAGKSTLFLHFNGILKPTSGEVLIKGEPIKydkkSLLEVRKTVG 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 80 MVFQSY--ALFPHmTVFENMAFGLKLAKTPKEEIDRKVREAARVLQLEALLERRPKALSGGQRQRVAIGRAIVRQPGVFL 157
Cdd:PRK13639 82 IVFQNPddQLFAP-TVEEDVAFGPLNLGLSKEEVEKRVKEALKAVGMEGFENKPPHHLSGGQKKRVAIAGILAMKPEIIV 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 158 FDEPLSNLDAtlrgQTRIEIARLHKQFAKA--SVVYVTHDQIEAMTLADKIVLLHAGKdterygsIAQIGAPLELYHRPK 235
Cdd:PRK13639 161 LDEPTSGLDP----MGASQIMKLLYDLNKEgiTIIISTHDVDLVPVYADKVYVMSDGK-------IIKEGTPKEVFSDIE 229
|
|
| cbiO |
PRK13649 |
energy-coupling factor transporter ATPase; |
3-213 |
2.47e-25 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184208 [Multi-domain] Cd Length: 280 Bit Score: 103.67 E-value: 2.47e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 3 SISLRGVQKAYGDGAP----VIRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLSIGGKIMN------DVP 72
Cdd:PRK13649 2 GINLQNVSYTYQAGTPfegrALFDVNLTIEDGSYTAFIGHTGSGKSTIMQLLNGLHVPTQGSVRVDDTLITstsknkDIK 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 73 AAQRGVAMVFQsyalFPHMTVFE-----NMAFGLKLAKTPKEEIDRKVREAARVLQL-EALLERRPKALSGGQRQRVAIG 146
Cdd:PRK13649 82 QIRKKVGLVFQ----FPESQLFEetvlkDVAFGPQNFGVSQEEAEALAREKLALVGIsESLFEKNPFELSGGQMRRVAIA 157
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 928002514 147 RAIVRQPGVFLFDEPLSNLDAtlrgQTRIEIARLHKQFAKA--SVVYVTHDQIEAMTLADKIVLLHAGK 213
Cdd:PRK13649 158 GILAMEPKILVLDEPTAGLDP----KGRKELMTLFKKLHQSgmTIVLVTHLMDDVANYADFVYVLEKGK 222
|
|
| LptB |
COG1137 |
ABC-type lipopolysaccharide export system, ATPase component [Cell wall/membrane/envelope ... |
1-166 |
2.96e-25 |
|
ABC-type lipopolysaccharide export system, ATPase component [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440752 [Multi-domain] Cd Length: 240 Bit Score: 102.41 E-value: 2.96e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 1 MASISLRGVQKAYGdGAPVIRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLSIGGKIMNDVPA---AQRG 77
Cdd:COG1137 1 MMTLEAENLVKSYG-KRTVVKDVSLEVNQGEIVGLLGPNGAGKTTTFYMIVGLVKPDSGRIFLDGEDITHLPMhkrARLG 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 78 VAMVFQSYALFPHMTVFEN-MAFgLKLAKTPKEEIDRKVREAARVLQLEALLERRPKALSGGQRQRVAIGRAIVRQPGVF 156
Cdd:COG1137 80 IGYLPQEASIFRKLTVEDNiLAV-LELRKLSKKEREERLEELLEEFGITHLRKSKAYSLSGGERRRVEIARALATNPKFI 158
|
170
....*....|
gi 928002514 157 LFDEPLSNLD 166
Cdd:COG1137 159 LLDEPFAGVD 168
|
|
| ABC_YhbG |
cd03218 |
ATP-binding cassette component of YhbG transport system; The ABC transporters belonging to the ... |
4-213 |
4.60e-25 |
|
ATP-binding cassette component of YhbG transport system; The ABC transporters belonging to the YhbG family are similar to members of the Mj1267_LivG family, which is involved in the transport of branched-chain amino acids. The genes yhbG and yhbN are located in a single operon and may function together in cell envelope during biogenesis. YhbG is the putative ATP-binding cassette component and YhbN is the putative periplasmic-binding protein. Depletion of each gene product leads to growth arrest, irreversible cell damage and loss of viability in E. coli. The YhbG homolog (NtrA) is essential in Rhizobium meliloti, a symbiotic nitrogen-fixing bacterium.
Pssm-ID: 213185 [Multi-domain] Cd Length: 232 Bit Score: 101.85 E-value: 4.60e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 4 ISLRGVQKAYGdGAPVIRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLSIGGKIMNDVPA---AQRGVAM 80
Cdd:cd03218 1 LRAENLSKRYG-KRKVVNGVSLSVKQGEIVGLLGPNGAGKTTTFYMIVGLVKPDSGKILLDGQDITKLPMhkrARLGIGY 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 81 VFQSYALFPHMTVFENMAFGLKLAKTPKEEIDRKVREAARVLQLEALLERRPKALSGGQRQRVAIGRAIVRQPGVFLFDE 160
Cdd:cd03218 80 LPQEASIFRKLTVEENILAVLEIRGLSKKEREEKLEELLEEFHITHLRKSKASSLSGGERRRVEIARALATNPKFLLLDE 159
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 928002514 161 PLSNLDATlrgqTRIEIARLHKQFAKASV-VYVT-HDQIEAMTLADKIVLLHAGK 213
Cdd:cd03218 160 PFAGVDPI----AVQDIQKIIKILKDRGIgVLITdHNVRETLSITDRAYIIYEGK 210
|
|
| hmuV |
PRK13548 |
hemin importer ATP-binding subunit; Provisional |
2-213 |
1.01e-24 |
|
hemin importer ATP-binding subunit; Provisional
Pssm-ID: 237422 [Multi-domain] Cd Length: 258 Bit Score: 101.39 E-value: 1.01e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 2 ASISLRGVQKAYGdGAPVIRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLSIGGKIMNDVPAAQ--RGVA 79
Cdd:PRK13548 1 AMLEARNLSVRLG-GRTLLDDVSLTLRPGEVVAILGPNGAGKSTLLRALSGELSPDSGEVRLNGRPLADWSPAElaRRRA 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 80 MVFQSYAL-FPhMTVFENMAFGLKLAKTPKEEIDRKVREAARVLQLEALLERRPKALSGGQRQRVAIGRAIVR------Q 152
Cdd:PRK13548 80 VLPQHSSLsFP-FTVEEVVAMGRAPHGLSRAEDDALVAAALAQVDLAHLAGRDYPQLSGGEQQRVQLARVLAQlwepdgP 158
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 928002514 153 PGVFLFDEPLSNLDatLRGQtrIEIARLHKQFAK---ASVVYVTHDQIEAMTLADKIVLLHAGK 213
Cdd:PRK13548 159 PRWLLLDEPTSALD--LAHQ--HHVLRLARQLAHergLAVIVVLHDLNLAARYADRIVLLHQGR 218
|
|
| PRK14239 |
PRK14239 |
phosphate transporter ATP-binding protein; Provisional |
20-224 |
1.35e-24 |
|
phosphate transporter ATP-binding protein; Provisional
Pssm-ID: 184585 [Multi-domain] Cd Length: 252 Bit Score: 101.01 E-value: 1.35e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 20 IRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLtDGDLSIGGKIM----------NDVPAAQRGVAMVFQSYALFP 89
Cdd:PRK14239 21 LNSVSLDFYPNEITALIGPSGSGKSTLLRSINRMNDL-NPEVTITGSIVynghniysprTDTVDLRKEIGMVFQQPNPFP 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 90 hMTVFENMAFGLKLA-----KTPKEEIDRKVREAARVLQLEALLERRPKALSGGQRQRVAIGRAIVRQPGVFLFDEPLSN 164
Cdd:PRK14239 100 -MSIYENVVYGLRLKgikdkQVLDEAVEKSLKGASIWDEVKDRLHDSALGLSGGQQQRVCIARVLATSPKIILLDEPTSA 178
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 165 LDATLRGQTRIEIARLHKQFakaSVVYVTHDQIEAMTLADKIVLLHAGKDTErYGSIAQI 224
Cdd:PRK14239 179 LDPISAGKIEETLLGLKDDY---TMLLVTRSMQQASRISDRTGFFLDGDLIE-YNDTKQM 234
|
|
| NHLM_micro_ABC2 |
TIGR03797 |
NHLM bacteriocin system ABC transporter, ATP-binding protein; Members of this protein family ... |
3-234 |
1.68e-24 |
|
NHLM bacteriocin system ABC transporter, ATP-binding protein; Members of this protein family are ABC transporter ATP-binding subunits, part of a three-gene putative bacteriocin transport operon. The other subunits include another ATP-binding subunit (TIGR03796), which has an N-terminal leader sequence cleavage domain, and an HlyD homolog (TIGR03794). In a number of genomes, members of protein families related to nitrile hydratase alpha subunit or to nif11 have undergone paralogous family expansions, with members possessing a putative bacteriocin cleavage region ending with a classic Gly-Gly motif. Those sets of putative bacteriocins, members of this protein family and its partners TIGR03794 and TIGR03796, and cyclodehydratase/docking scaffold fusion proteins of thiazole/oxazole biosynthesis frequently show correlated species distribution and co-clustering within many of those genomes. [Transport and binding proteins, Amino acids, peptides and amines, Cellular processes, Biosynthesis of natural products]
Pssm-ID: 274789 [Multi-domain] Cd Length: 686 Bit Score: 105.42 E-value: 1.68e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 3 SISLRGVQKAYG-DGAPVIRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLSIGGKIMN--DVPAAQRGVA 79
Cdd:TIGR03797 451 AIEVDRVTFRYRpDGPLILDDVSLQIEPGEFVAIVGPSGSGKSTLLRLLLGFETPESGSVFYDGQDLAglDVQAVRRQLG 530
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 80 MVFQSYALFPHmTVFENMAFGLKLakTPKEeidrkVREAARVLQLEALLERRP-----------KALSGGQRQRVAIGRA 148
Cdd:TIGR03797 531 VVLQNGRLMSG-SIFENIAGGAPL--TLDE-----AWEAARMAGLAEDIRAMPmgmhtviseggGTLSGGQRQRLLIARA 602
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 149 IVRQPGVFLFDEPLSNLD-----------ATLRGqTRIEIA-RLhkqfakaSVVyvthdqieamTLADKIVLLHAGKdte 216
Cdd:TIGR03797 603 LVRKPRILLFDEATSALDnrtqaivseslERLKV-TRIVIAhRL-------STI----------RNADRIYVLDAGR--- 661
|
250
....*....|....*...
gi 928002514 217 rygsIAQIGAPLELYHRP 234
Cdd:TIGR03797 662 ----VVQQGTYDELMARE 675
|
|
| ABCG_EPDR |
cd03213 |
Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette ... |
18-213 |
1.69e-24 |
|
Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette superfamily; ABCG transporters are involved in eye pigment (EP) precursor transport, regulation of lipid-trafficking mechanisms, and pleiotropic drug resistance (DR). DR is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. Compared to other members of the ABC transporter subfamilies, the ABCG transporter family is composed of proteins that have an ATP-binding cassette domain at the N-terminus and a TM (transmembrane) domain at the C-terminus.
Pssm-ID: 213180 [Multi-domain] Cd Length: 194 Bit Score: 99.16 E-value: 1.69e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 18 PVIRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAG-LEDLTD-GDLSIGGK-IMNDVPAAQrgVAMVFQSYALFPHMTVF 94
Cdd:cd03213 23 QLLKNVSGKAKPGELTAIMGPSGAGKSTLLNALAGrRTGLGVsGEVLINGRpLDKRSFRKI--IGYVPQDDILHPTLTVR 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 95 ENMAFGLKLaktpkeeidrkvreaarvlqleallerrpKALSGGQRQRVAIGRAIVRQPGVFLFDEPLSNLDATlrgqTR 174
Cdd:cd03213 101 ETLMFAAKL-----------------------------RGLSGGERKRVSIALELVSNPSLLFLDEPTSGLDSS----SA 147
|
170 180 190 200
....*....|....*....|....*....|....*....|..
gi 928002514 175 IEIARLHKQFAKA--SVVYVTHD-QIEAMTLADKIVLLHAGK 213
Cdd:cd03213 148 LQVMSLLRRLADTgrTIICSIHQpSSEIFELFDKLLLLSQGR 189
|
|
| ABCC_MRP_domain1 |
cd03250 |
ATP-binding cassette domain 1 of multidrug resistance-associated protein, subfamily C; This ... |
15-213 |
1.79e-24 |
|
ATP-binding cassette domain 1 of multidrug resistance-associated protein, subfamily C; This subfamily is also known as MRP (multidrug resistance-associated protein). Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resisting lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions, such as glutathione, glucuronate, and sulfate.
Pssm-ID: 213217 [Multi-domain] Cd Length: 204 Bit Score: 99.47 E-value: 1.79e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 15 DGAPVIRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLSIGGKImndvpaaqrgvAMVFQSYALFPhMTVF 94
Cdd:cd03250 16 ETSFTLKDINLEVPKGELVAIVGPVGSGKSSLLSALLGELEKLSGSVSVPGSI-----------AYVSQEPWIQN-GTIR 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 95 ENMAFGlklaktpkEEID-RKVREAARVLQLEALLERRPK-----------ALSGGQRQRVAIGRAIVRQPGVFLFDEPL 162
Cdd:cd03250 84 ENILFG--------KPFDeERYEKVIKACALEPDLEILPDgdlteigekgiNLSGGQKQRISLARAVYSDADIYLLDDPL 155
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 928002514 163 SNLDA--------------TLRGQTRIeiarlhkqfakasvvYVTHdQIEAMTLADKIVLLHAGK 213
Cdd:cd03250 156 SAVDAhvgrhifencilglLLNNKTRI---------------LVTH-QLQLLPHADQIVVLDNGR 204
|
|
| cbiO |
PRK13645 |
energy-coupling factor transporter ATPase; |
4-231 |
3.23e-24 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184204 [Multi-domain] Cd Length: 289 Bit Score: 100.85 E-value: 3.23e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 4 ISLRGVQKAYGDGAP----VIRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGL-----EDLTDGDLSI--GGKIMNDVP 72
Cdd:PRK13645 7 IILDNVSYTYAKKTPfefkALNNTSLTFKKNKVTCVIGTTGSGKSTMIQLTNGLiisetGQTIVGDYAIpaNLKKIKEVK 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 73 AAQRGVAMVFQ--SYALFPHmTVFENMAFGLKLAKTPKEEIDRKVREAARVLQL-EALLERRPKALSGGQRQRVAIGRAI 149
Cdd:PRK13645 87 RLRKEIGLVFQfpEYQLFQE-TIEKDIAFGPVNLGENKQEAYKKVPELLKLVQLpEDYVKRSPFELSGGQKRRVALAGII 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 150 VRQPGVFLFDEPLSNLDATLRGQTRIEIARLHKQFAKaSVVYVTHDQIEAMTLADKIVLLHAGKdterygsIAQIGAPLE 229
Cdd:PRK13645 166 AMDGNTLVLDEPTGGLDPKGEEDFINLFERLNKEYKK-RIIMVTHNMDQVLRIADEVIVMHEGK-------VISIGSPFE 237
|
..
gi 928002514 230 LY 231
Cdd:PRK13645 238 IF 239
|
|
| ABC_MTABC3_MDL1_MDL2 |
cd03249 |
ATP-binding cassette domain of a mitochondrial protein MTABC3 and related proteins; MTABC3 ... |
4-232 |
1.10e-23 |
|
ATP-binding cassette domain of a mitochondrial protein MTABC3 and related proteins; MTABC3 (also known as ABCB6) is a mitochondrial ATP-binding cassette protein involved in iron homeostasis and one of four ABC transporters expressed in the mitochondrial inner membrane, the other three being MDL1(ABC7), MDL2, and ATM1. In fact, the yeast MDL1 (multidrug resistance-like protein 1) and MDL2 (multidrug resistance-like protein 2) transporters are also included in this CD. MDL1 is an ATP-dependent permease that acts as a high-copy suppressor of ATM1 and is thought to have a role in resistance to oxidative stress. Interestingly, subfamily B is more closely related to the carboxyl-terminal component of subfamily C than the two halves of ABCC molecules are with one another.
Pssm-ID: 213216 [Multi-domain] Cd Length: 238 Bit Score: 98.00 E-value: 1.10e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 4 ISLRGVQKAYGD--GAPVIRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLSIGGKIMND--VPAAQRGVA 79
Cdd:cd03249 1 IEFKNVSFRYPSrpDVPILKGLSLTIPPGKTVALVGSSGCGKSTVVSLLERFYDPTSGEILLDGVDIRDlnLRWLRSQIG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 80 MVFQSYALFPhMTVFENMAFGLKLAKTpkEEIDRKVREAA-----RVL--QLEALLERRPKALSGGQRQRVAIGRAIVRQ 152
Cdd:cd03249 81 LVSQEPVLFD-GTIAENIRYGKPDATD--EEVEEAAKKANihdfiMSLpdGYDTLVGERGSQLSGGQKQRIAIARALLRN 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 153 PGVFLFDEPLSNLDA--------TL----RGQTRIEIA-RLHkqfakasvvyvthdqieamTL--ADKIVLLHAGKDTER 217
Cdd:cd03249 158 PKILLLDEATSALDAeseklvqeALdramKGRTTIVIAhRLS-------------------TIrnADLIAVLQNGQVVEQ 218
|
250
....*....|....*
gi 928002514 218 yGSIAQIGAPLELYH 232
Cdd:cd03249 219 -GTHDELMAQKGVYA 232
|
|
| cbiO |
PRK13650 |
energy-coupling factor transporter ATPase; |
18-233 |
2.36e-23 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184209 [Multi-domain] Cd Length: 279 Bit Score: 98.27 E-value: 2.36e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 18 PVIRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLSIGGKIM--NDVPAAQRGVAMVFQSY-ALFPHMTVF 94
Cdd:PRK13650 21 YTLNDVSFHVKQGEWLSIIGHNGSGKSTTVRLIDGLLEAESGQIIIDGDLLteENVWDIRHKIGMVFQNPdNQFVGATVE 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 95 ENMAFGLKLAKTPKEEIDRKVREAARVLQLEALLERRPKALSGGQRQRVAIGRAIVRQPGVFLFDEPLSNLDATLRgQTR 174
Cdd:PRK13650 101 DDVAFGLENKGIPHEEMKERVNEALELVGMQDFKEREPARLSGGQKQRVAIAGAVAMRPKIIILDEATSMLDPEGR-LEL 179
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 928002514 175 IEIARLHKQFAKASVVYVTHDqIEAMTLADKIVLLHAGKdterygsIAQIGAPLELYHR 233
Cdd:PRK13650 180 IKTIKGIRDDYQMTVISITHD-LDEVALSDRVLVMKNGQ-------VESTSTPRELFSR 230
|
|
| PRK10584 |
PRK10584 |
putative ABC transporter ATP-binding protein YbbA; Provisional |
23-195 |
2.40e-23 |
|
putative ABC transporter ATP-binding protein YbbA; Provisional
Pssm-ID: 182569 [Multi-domain] Cd Length: 228 Bit Score: 97.16 E-value: 2.40e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 23 VDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLSIGGKIMNDVPAAQRG------VAMVFQSYALFPHMTVFEN 96
Cdd:PRK10584 29 VELVVKRGETIALIGESGSGKSTLLAILAGLDDGSSGEVSLVGQPLHQMDEEARAklrakhVGFVFQSFMLIPTLNALEN 108
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 97 mafgLKLAKTPKEEIDRKVREAARVLQLEALLERR----PKALSGGQRQRVAIGRAIVRQPGVFLFDEPLSNLDAtlrgQ 172
Cdd:PRK10584 109 ----VELPALLRGESSRQSRNGAKALLEQLGLGKRldhlPAQLSGGEQQRVALARAFNGRPDVLFADEPTGNLDR----Q 180
|
170 180
....*....|....*....|....*..
gi 928002514 173 TRIEIA----RLHKQFAkASVVYVTHD 195
Cdd:PRK10584 181 TGDKIAdllfSLNREHG-TTLILVTHD 206
|
|
| cbiO |
PRK13642 |
energy-coupling factor transporter ATPase; |
23-231 |
6.04e-23 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184202 [Multi-domain] Cd Length: 277 Bit Score: 97.09 E-value: 6.04e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 23 VDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLSIGGKIMN--DVPAAQRGVAMVFQSY-ALFPHMTVFENMAF 99
Cdd:PRK13642 26 VSFSITKGEWVSIIGQNGSGKSTTARLIDGLFEEFEGKVKIDGELLTaeNVWNLRRKIGMVFQNPdNQFVGATVEDDVAF 105
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 100 GLKLAKTPKEEIDRKVREAARVLQLEALLERRPKALSGGQRQRVAIGRAIVRQPGVFLFDEPLSNLDATLRGQTRIEIAR 179
Cdd:PRK13642 106 GMENQGIPREEMIKRVDEALLAVNMLDFKTREPARLSGGQKQRVAVAGIIALRPEIIILDESTSMLDPTGRQEIMRVIHE 185
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 928002514 180 LHKQFaKASVVYVTHDQIEAMTlADKIVLLHAGKdterygsIAQIGAPLELY 231
Cdd:PRK13642 186 IKEKY-QLTVLSITHDLDEAAS-SDRILVMKAGE-------IIKEAAPSELF 228
|
|
| met_CoM_red_A2 |
TIGR03269 |
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in ... |
7-230 |
6.31e-23 |
|
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in methanogenesis, methyl coenzyme M reductase, contains alpha, beta, and gamma chains. In older literature, the complex of alpha, beta, and gamma chains was termed component C, while this single chain protein was termed methyl coenzyme M reductase system component A2. [Energy metabolism, Methanogenesis]
Pssm-ID: 132313 [Multi-domain] Cd Length: 520 Bit Score: 100.26 E-value: 6.31e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 7 RGVQKAygdgapvIRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLS--IGGKI--MNDVPAAQRGVA--- 79
Cdd:TIGR03269 294 RGVVKA-------VDNVSLEVKEGEIFGIVGTSGAGKTTLSKIIAGVLEPTSGEVNvrVGDEWvdMTKPGPDGRGRAkry 366
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 80 --MVFQSYALFPHMTVFENM--AFGLKLaktPKEeidRKVREAARVLQL--------EALLERRPKALSGGQRQRVAIGR 147
Cdd:TIGR03269 367 igILHQEYDLYPHRTVLDNLteAIGLEL---PDE---LARMKAVITLKMvgfdeekaEEILDKYPDELSEGERHRVALAQ 440
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 148 AIVRQPGVFLFDEPLSNLDATLRGQTRIEIARLHKQFAKASVVyVTHDQIEAMTLADKIVLLhagkdteRYGSIAQIGAP 227
Cdd:TIGR03269 441 VLIKEPRIVILDEPTGTMDPITKVDVTHSILKAREEMEQTFII-VSHDMDFVLDVCDRAALM-------RDGKIVKIGDP 512
|
...
gi 928002514 228 LEL 230
Cdd:TIGR03269 513 EEI 515
|
|
| fecE |
PRK11231 |
Fe(3+) dicitrate ABC transporter ATP-binding protein FecE; |
3-229 |
1.14e-22 |
|
Fe(3+) dicitrate ABC transporter ATP-binding protein FecE;
Pssm-ID: 183044 [Multi-domain] Cd Length: 255 Bit Score: 95.85 E-value: 1.14e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 3 SISLRGVQKAYGDgAPVIRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLSIGGKIMNDVPAAQ--RGVAM 80
Cdd:PRK11231 2 TLRTENLTVGYGT-KRILNDLSLSLPTGKITALIGPNGCGKSTLLKCFARLLTPQSGTVFLGDKPISMLSSRQlaRRLAL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 81 VFQSYALFPHMTVFENMAFG----LKLAKTPKEEIDRKVREAARVLQLEALLERRPKALSGGQRQRVAIGRAIVRQPGVF 156
Cdd:PRK11231 81 LPQHHLTPEGITVRELVAYGrspwLSLWGRLSAEDNARVNQAMEQTRINHLADRRLTDLSGGQRQRAFLAMVLAQDTPVV 160
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 928002514 157 LFDEPLSNLDatLRGQtrIEIARLHKQFAKA--SVVYVTHDQIEAMTLADKIVLLHAGKdterygSIAQiGAPLE 229
Cdd:PRK11231 161 LLDEPTTYLD--INHQ--VELMRLMRELNTQgkTVVTVLHDLNQASRYCDHLVVLANGH------VMAQ-GTPEE 224
|
|
| ATM1 |
COG5265 |
ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components ... |
2-217 |
2.67e-22 |
|
ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 444078 [Multi-domain] Cd Length: 605 Bit Score: 98.74 E-value: 2.67e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 2 ASISLRGVQKAYGDGAPVIRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLSIGGKIMNDVPAA--QRGVA 79
Cdd:COG5265 356 GEVRFENVSFGYDPERPILKGVSFEVPAGKTVAIVGPSGAGKSTLARLLFRFYDVTSGRILIDGQDIRDVTQAslRAAIG 435
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 80 MVFQSYALFpHMTVFENMAFGlKLAKTPKEeidrkVREAARVLQLEALLERRPKA-----------LSGGQRQRVAIGRA 148
Cdd:COG5265 436 IVPQDTVLF-NDTIAYNIAYG-RPDASEEE-----VEAAARAAQIHDFIESLPDGydtrvgerglkLSGGEKQRVAIART 508
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 149 IVRQPGVFLFDEPLSNLD--------ATL----RGQTRIEIA-RLhkqfakaSVvyVTHdqieamtlADKIVLLHAGKDT 215
Cdd:COG5265 509 LLKNPPILIFDEATSALDsrteraiqAALrevaRGRTTLVIAhRL-------ST--IVD--------ADEILVLEAGRIV 571
|
..
gi 928002514 216 ER 217
Cdd:COG5265 572 ER 573
|
|
| PRK13633 |
PRK13633 |
energy-coupling factor transporter ATPase; |
18-213 |
3.33e-22 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 237453 [Multi-domain] Cd Length: 280 Bit Score: 95.15 E-value: 3.33e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 18 PVIRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLSIGG---KIMNDVPAAQRGVAMVFQSyalfPH---- 90
Cdd:PRK13633 24 LALDDVNLEVKKGEFLVILGRNGSGKSTIAKHMNALLIPSEGKVYVDGldtSDEENLWDIRNKAGMVFQN----PDnqiv 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 91 -MTVFENMAFGLKLAKTPKEEIDRKVREAARVLQLEALLERRPKALSGGQRQRVAIGRAIVRQPGVFLFDEPLSNLDATL 169
Cdd:PRK13633 100 aTIVEEDVAFGPENLGIPPEEIRERVDESLKKVGMYEYRRHAPHLLSGGQKQRVAIAGILAMRPECIIFDEPTAMLDPSG 179
|
170 180 190 200
....*....|....*....|....*....|....*....|....
gi 928002514 170 RGQTRIEIARLHKQFAkASVVYVTHDQIEAMTlADKIVLLHAGK 213
Cdd:PRK13633 180 RREVVNTIKELNKKYG-ITIILITHYMEEAVE-ADRIIVMDSGK 221
|
|
| YejF |
COG4172 |
ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites ... |
22-224 |
3.75e-22 |
|
ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites biosynthesis, transport and catabolism];
Pssm-ID: 443332 [Multi-domain] Cd Length: 533 Bit Score: 97.83 E-value: 3.75e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 22 DVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDlTDGDLSIGGKIMNDVPAAQ-----RGVAMVFQS-YA-LFPHMTVF 94
Cdd:COG4172 304 GVSLTLRRGETLGLVGESGSGKSTLGLALLRLIP-SEGEIRFDGQDLDGLSRRAlrplrRRMQVVFQDpFGsLSPRMTVG 382
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 95 ENMAFGLKLAKTP--KEEIDRKVREA-ARVLQLEALLERRPKALSGGQRQRVAIGRAIVRQPGVFLFDEPLSNLDATLRG 171
Cdd:COG4172 383 QIIAEGLRVHGPGlsAAERRARVAEAlEEVGLDPAARHRYPHEFSGGQRQRIAIARALILEPKLLVLDEPTSALDVSVQA 462
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 928002514 172 QTrIEI-ARLHKQFaKASVVYVTHDQ--IEAMtlADKIVLLHAGKDTERyGSIAQI 224
Cdd:COG4172 463 QI-LDLlRDLQREH-GLAYLFISHDLavVRAL--AHRVMVMKDGKVVEQ-GPTEQV 513
|
|
| ABCG_White |
cd03234 |
White pigment protein homolog of ABCG transporter subfamily; The White subfamily represents ... |
19-213 |
3.98e-22 |
|
White pigment protein homolog of ABCG transporter subfamily; The White subfamily represents ABC transporters homologous to the Drosophila white gene, which acts as a dimeric importer for eye pigment precursors. The eye pigmentation of Drosophila is developed from the synthesis and deposition in the cells of red pigments, which are synthesized from guanine, and brown pigments, which are synthesized from tryptophan. The pigment precursors are encoded by the white, brown, and scarlet genes, respectively. Evidence from genetic and biochemical studies suggest that the White and Brown proteins function as heterodimers to import guanine, while the White and Scarlet proteins function to import tryptophan. However, a recent study also suggests that White may be involved in the transport of a metabolite, such as 3-hydroxykynurenine, across intracellular membranes. Mammalian ABC transporters belonging to the White subfamily (ABCG1, ABCG5, and ABCG8) have been shown to be involved in the regulation of lipid-trafficking mechanisms in macrophages, hepatocytes, and intestinal mucosa cells. ABCG1 (ABC8), the human homolog of the Drosophila white gene is induced in monocyte-derived macrophages during cholesterol influx mediated by acetylated low-density lipoprotein. It is possible that human ABCG1 forms heterodimers with several heterologous partners.
Pssm-ID: 213201 [Multi-domain] Cd Length: 226 Bit Score: 93.49 E-value: 3.98e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 19 VIRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLED---LTDGDLSIGGKIMNdvPAA-QRGVAMVFQSYALFPHMTVF 94
Cdd:cd03234 22 ILNDVSLHVESGQVMAILGSSGSGKTTLLDAISGRVEgggTTSGQILFNGQPRK--PDQfQKCVAYVRQDDILLPGLTVR 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 95 ENMAFG--LKLAKTPKEEIDRKVREAARVLQL--EALLERRPKALSGGQRQRVAIGRAIVRQPGVFLFDEPLSNLDATlr 170
Cdd:cd03234 100 ETLTYTaiLRLPRKSSDAIRKKRVEDVLLRDLalTRIGGNLVKGISGGERRRVSIAVQLLWDPKVLILDEPTSGLDSF-- 177
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 928002514 171 gqTRIEIARLHKQFAKA-SVVYVTHDQ--IEAMTLADKIVLLHAGK 213
Cdd:cd03234 178 --TALNLVSTLSQLARRnRIVILTIHQprSDLFRLFDRILLLSSGE 221
|
|
| YhaQ |
COG4152 |
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ... |
3-224 |
5.29e-22 |
|
ABC-type uncharacterized transport system, ATPase component [General function prediction only];
Pssm-ID: 443322 [Multi-domain] Cd Length: 298 Bit Score: 94.79 E-value: 5.29e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 3 SISLRGVQKAYGDgAPVIRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLSIGGKIMNDVPAAQ------- 75
Cdd:COG4152 1 MLELKGLTKRFGD-KTAVDDVSFTVPKGEIFGLLGPNGAGKTTTIRIILGILAPDSGEVLWDGEPLDPEDRRRigylpee 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 76 RGvamvfqsyaLFPHMTVFENMAFGLKLAKTPKEEIDRKVREAARVLQLEALLERRPKALSGGQRQRVAIGRAIVRQPGV 155
Cdd:COG4152 80 RG---------LYPKMKVGEQLVYLARLKGLSKAEAKRRADEWLERLGLGDRANKKVEELSKGNQQKVQLIAALLHDPEL 150
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 928002514 156 FLFDEPLSNLDATLRGQTRIEIARLHKQfaKASVVYVTH--DQIEAmtLADKIVLLHAGKdTERYGSIAQI 224
Cdd:COG4152 151 LILDEPFSGLDPVNVELLKDVIRELAAK--GTTVIFSSHqmELVEE--LCDRIVIINKGR-KVLSGSVDEI 216
|
|
| ABCC_Hemolysin |
cd03252 |
ATP-binding cassette domain of hemolysin B, subfamily C; The ABC-transporter hemolysin B is a ... |
4-216 |
5.38e-22 |
|
ATP-binding cassette domain of hemolysin B, subfamily C; The ABC-transporter hemolysin B is a central component of the secretion machinery that translocates the toxin, hemolysin A, in a Sec-independent fashion across both membranes of E. coli. The hemolysin A (HlyA) transport machinery is composed of the ATP-binding cassette (ABC) transporter HlyB located in the inner membrane, hemolysin D (HlyD), also anchored in the inner membrane, and TolC, which resides in the outer membrane. HlyD apparently forms a continuous channel that bridges the entire periplasm, interacting with TolC and HlyB. This arrangement prevents the appearance of periplasmic intermediates of HlyA during substrate transport. Little is known about the molecular details of HlyA transport, but it is evident that ATP-hydrolysis by the ABC-transporter HlyB is a necessary source of energy.
Pssm-ID: 213219 [Multi-domain] Cd Length: 237 Bit Score: 93.70 E-value: 5.38e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 4 ISLRGVQKAY-GDGAPVIRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLSIGGKIMNDVPAA--QRGVAM 80
Cdd:cd03252 1 ITFEHVRFRYkPDGPVILDNISLRIKPGEVVGIVGRSGSGKSTLTKLIQRFYVPENGRVLVDGHDLALADPAwlRRQVGV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 81 VFQSYALFpHMTVFENMAFGLKLAKTpkeeidRKVREAAR-------VLQL----EALLERRPKALSGGQRQRVAIGRAI 149
Cdd:cd03252 81 VLQENVLF-NRSIRDNIALADPGMSM------ERVIEAAKlagahdfISELpegyDTIVGEQGAGLSGGQRQRIAIARAL 153
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 928002514 150 VRQPGVFLFDEPLSNLDATlrgQTRIEIARLHKQFAKASVVYVTHdQIEAMTLADKIVLLHAGKDTE 216
Cdd:cd03252 154 IHNPRILIFDEATSALDYE---SEHAIMRNMHDICAGRTVIIIAH-RLSTVKNADRIIVMEKGRIVE 216
|
|
| PRK11831 |
PRK11831 |
phospholipid ABC transporter ATP-binding protein MlaF; |
4-246 |
6.28e-22 |
|
phospholipid ABC transporter ATP-binding protein MlaF;
Pssm-ID: 236997 [Multi-domain] Cd Length: 269 Bit Score: 94.06 E-value: 6.28e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 4 ISLRGVQKAYGDgAPVIRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLSIGGkimNDVPAAQRG------ 77
Cdd:PRK11831 8 VDMRGVSFTRGN-RCIFDNISLTVPRGKITAIMGPSGIGKTTLLRLIGGQIAPDHGEILFDG---ENIPAMSRSrlytvr 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 78 --VAMVFQSYALFPHMTVFENMAFGLKLAKTPKEEIDRkvreAARVLQLEALLER-----RPKALSGGQRQRVAIGRAIV 150
Cdd:PRK11831 84 krMSMLFQSGALFTDMNVFDNVAYPLREHTQLPAPLLH----STVMMKLEAVGLRgaaklMPSELSGGMARRAALARAIA 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 151 RQPGVFLFDEPLSNLDATLRGQTRIEIARLHKQFAKASVVyVTHDQIEAMTLADKIVLLhAGKDTerygsIAQiGAPLEL 230
Cdd:PRK11831 160 LEPDLIMFDEPFVGQDPITMGVLVKLISELNSALGVTCVV-VSHDVPEVLSIADHAYIV-ADKKI-----VAH-GSAQAL 231
|
250
....*....|....*....
gi 928002514 231 YHRPKSR---FVAGFIGSP 246
Cdd:PRK11831 232 QANPDPRvrqFLDGIADGP 250
|
|
| PRK10535 |
PRK10535 |
macrolide ABC transporter ATP-binding protein/permease MacB; |
2-242 |
8.04e-22 |
|
macrolide ABC transporter ATP-binding protein/permease MacB;
Pssm-ID: 182528 [Multi-domain] Cd Length: 648 Bit Score: 97.10 E-value: 8.04e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 2 ASISLRGVQKAYGDG---APVIRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLSIGGK----IMNDVPAA 74
Cdd:PRK10535 3 ALLELKDIRRSYPSGeeqVEVLKGISLDIYAGEMVAIVGASGSGKSTLMNILGCLDKPTSGTYRVAGQdvatLDADALAQ 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 75 QR--GVAMVFQSYALFPHMTVFENMAFGLKLAKTPKEEIDRKVREAARVLQLEALLERRPKALSGGQRQRVAIGRAIVRQ 152
Cdd:PRK10535 83 LRreHFGFIFQRYHLLSHLTAAQNVEVPAVYAGLERKQRLLRAQELLQRLGLEDRVEYQPSQLSGGQQQRVSIARALMNG 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 153 PGVFLFDEPLSNLDAtlrgQTRIEIARLHKQFAKA--SVVYVTHD-QIEAMtlADKIVLLHAGK---DTERYGSIAQIGA 226
Cdd:PRK10535 163 GQVILADEPTGALDS----HSGEEVMAILHQLRDRghTVIIVTHDpQVAAQ--AERVIEIRDGEivrNPPAQEKVNVAGG 236
|
250
....*....|....*...
gi 928002514 227 PLELYHRPKS--RFVAGF 242
Cdd:PRK10535 237 TEPVVNTASGwrQFVSGF 254
|
|
| PRK09984 |
PRK09984 |
phosphonate ABC transporter ATP-binding protein; |
23-212 |
1.03e-21 |
|
phosphonate ABC transporter ATP-binding protein;
Pssm-ID: 182182 [Multi-domain] Cd Length: 262 Bit Score: 93.54 E-value: 1.03e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 23 VDLEIGENEFCVFLGPSGCGKSTLLCMIAGLedlTDGDLSIG-------------GKIMNDVPAAQRGVAMVFQSYALFP 89
Cdd:PRK09984 23 VDLNIHHGEMVALLGPSGSGKSTLLRHLSGL---ITGDKSAGshiellgrtvqreGRLARDIRKSRANTGYIFQQFNLVN 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 90 HMTVFENMAFGlKLAKTP----------KEEIDRKVREAARVlQLEALLERRPKALSGGQRQRVAIGRAIVRQPGVFLFD 159
Cdd:PRK09984 100 RLSVLENVLIG-ALGSTPfwrtcfswftREQKQRALQALTRV-GMVHFAHQRVSTLSGGQQQRVAIARALMQQAKVILAD 177
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 928002514 160 EPLSNLDATlrgQTRIEIARLH--KQFAKASVVYVTHDQIEAMTLADKIVLLHAG 212
Cdd:PRK09984 178 EPIASLDPE---SARIVMDTLRdiNQNDGITVVVTLHQVDYALRYCERIVALRQG 229
|
|
| Uup |
COG0488 |
ATPase components of ABC transporters with duplicated ATPase domains [General function ... |
6-213 |
1.14e-21 |
|
ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only];
Pssm-ID: 440254 [Multi-domain] Cd Length: 520 Bit Score: 96.29 E-value: 1.14e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 6 LRGVQKAYGdGAPVIRDVDLEIGENEfCV-FLGPSGCGKSTLLCMIAGLEDLTDGDLSIGGKImndvpaaqRgVAMVFQS 84
Cdd:COG0488 1 LENLSKSFG-GRPLLDDVSLSINPGD-RIgLVGRNGAGKSTLLKILAGELEPDSGEVSIPKGL--------R-IGYLPQE 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 85 YALFPHMTVFENMAFGL---------------KLAKTPKE-----------------EIDRKVREAARVLQL-EALLERR 131
Cdd:COG0488 70 PPLDDDLTVLDTVLDGDaelraleaeleeleaKLAEPDEDlerlaelqeefealggwEAEARAEEILSGLGFpEEDLDRP 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 132 PKALSGGQRQRVAIGRAIVRQPGVFLFDEPLSNLDatlrgqtrIE-IARLH---KQFAKAsVVYVTHDQ--IEAMtlADK 205
Cdd:COG0488 150 VSELSGGWRRRVALARALLSEPDLLLLDEPTNHLD--------LEsIEWLEeflKNYPGT-VLVVSHDRyfLDRV--ATR 218
|
....*...
gi 928002514 206 IVLLHAGK 213
Cdd:COG0488 219 ILELDRGK 226
|
|
| CydC |
TIGR02868 |
thiol reductant ABC exporter, CydC subunit; The gene pair cydCD encodes an ABC-family ... |
2-195 |
1.52e-21 |
|
thiol reductant ABC exporter, CydC subunit; The gene pair cydCD encodes an ABC-family transporter in which each gene contains an N-terminal membrane-spanning domain (pfam00664) and a C-terminal ATP-binding domain (pfam00005). In E. coli these genes were discovered as mutants which caused the terminal heme-copper oxidase complex cytochrome bd to fail to assemble. Recent work has shown that the transporter is involved in export of redox-active thiol compounds such as cysteine and glutathione. The linkage to assembly of the cytochrome bd complex is further supported by the conserved operon structure found outside the gammaproteobacteria (cydABCD) containing both the transporter and oxidase genes components. The genes used as the seed members for this model are all either found in the gammproteobacterial context or the CydABCD context. All members of this family scoring above trusted at the time of its creation were from genomes which encode a cytochrome bd complex.
Pssm-ID: 274331 [Multi-domain] Cd Length: 530 Bit Score: 95.89 E-value: 1.52e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 2 ASISLRGVQKAYGDGAPVIRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLSIGGKIMNDVP--AAQRGVA 79
Cdd:TIGR02868 333 PTLELRDLSAGYPGAPPVLDGVSLDLPPGERVAILGPSGSGKSTLLATLAGLLDPLQGEVTLDGVPVSSLDqdEVRRRVS 412
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 80 MVFQSYALFpHMTVFENMAFGlklaktPKEEIDRKVREAARVLQLEALLERRP-----------KALSGGQRQRVAIGRA 148
Cdd:TIGR02868 413 VCAQDAHLF-DTTVRENLRLA------RPDATDEELWAALERVGLADWLRALPdgldtvlgeggARLSGGERQRLALARA 485
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 928002514 149 IVRQPGVFLFDEPLSNLDATLRGQTrieIARLHKQFAKASVVYVTHD 195
Cdd:TIGR02868 486 LLADAPILLLDEPTEHLDAETADEL---LEDLLAALSGRTVVLITHH 529
|
|
| type_I_sec_PrtD |
TIGR01842 |
type I secretion system ABC transporter, PrtD family; Type I protein secretion is a system in ... |
17-212 |
1.83e-21 |
|
type I secretion system ABC transporter, PrtD family; Type I protein secretion is a system in some Gram-negative bacteria to export proteins (often proteases) across both inner and outer membranes to the extracellular medium. This is one of three proteins of the type I secretion apparatus. Targeted proteins are not cleaved at the N-terminus, but rather carry signals located toward the extreme C-terminus to direct type I secretion. [Protein fate, Protein and peptide secretion and trafficking]
Pssm-ID: 200134 [Multi-domain] Cd Length: 544 Bit Score: 95.88 E-value: 1.83e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 17 APVIRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLSIGGKIMNDVPAAQRG--VAMVFQSYALFPHmTVF 94
Cdd:TIGR01842 331 KPTLRGISFSLQAGEALAIIGPSGSGKSTLARLIVGIWPPTSGSVRLDGADLKQWDRETFGkhIGYLPQDVELFPG-TVA 409
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 95 ENMA-FGlklaktpkEEID-RKVREAARVLQLEALLERRPK-----------ALSGGQRQRVAIGRAIVRQPGVFLFDEP 161
Cdd:TIGR01842 410 ENIArFG--------ENADpEKIIEAAKLAGVHELILRLPDgydtvigpggaTLSGGQRQRIALARALYGDPKLVVLDEP 481
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 928002514 162 LSNLDATlrGQTRIEIARLHKQFAKASVVYVTHdQIEAMTLADKIVLLHAG 212
Cdd:TIGR01842 482 NSNLDEE--GEQALANAIKALKARGITVVVITH-RPSLLGCVDKILVLQDG 529
|
|
| cbiO |
PRK13643 |
energy-coupling factor transporter ATPase; |
4-232 |
1.96e-21 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184203 [Multi-domain] Cd Length: 288 Bit Score: 93.26 E-value: 1.96e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 4 ISLRGVQKAYGDGAP----VIRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLSIGGKIMN------DVPA 73
Cdd:PRK13643 2 IKFEKVNYTYQPNSPfasrALFDIDLEVKKGSYTALIGHTGSGKSTLLQHLNGLLQPTEGKVTVGDIVVSstskqkEIKP 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 74 AQRGVAMVFQsyalFPHMTVFE-----NMAFGLKLAKTPKEEIDRKVREAARVLQL-EALLERRPKALSGGQRQRVAIGR 147
Cdd:PRK13643 82 VRKKVGVVFQ----FPESQLFEetvlkDVAFGPQNFGIPKEKAEKIAAEKLEMVGLaDEFWEKSPFELSGGQMRRVAIAG 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 148 AIVRQPGVFLFDEPLSNLDAtlrgQTRIEIARLHKQFAKA--SVVYVTHDQIEAMTLADKIVLLHAGKdterygsIAQIG 225
Cdd:PRK13643 158 ILAMEPEVLVLDEPTAGLDP----KARIEMMQLFESIHQSgqTVVLVTHLMDDVADYADYVYLLEKGH-------IISCG 226
|
....*..
gi 928002514 226 APLELYH 232
Cdd:PRK13643 227 TPSDVFQ 233
|
|
| cbiO |
PRK13648 |
cobalt transporter ATP-binding subunit; Provisional |
4-231 |
2.47e-21 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 184207 [Multi-domain] Cd Length: 269 Bit Score: 92.51 E-value: 2.47e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 4 ISLRGVQKAY-GDGAPVIRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDG-----DLSIGGKIMNDVpaaQRG 77
Cdd:PRK13648 8 IVFKNVSFQYqSDASFTLKDVSFNIPKGQWTSIVGHNGSGKSTIAKLMIGIEKVKSGeifynNQAITDDNFEKL---RKH 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 78 VAMVFQS-YALFPHMTVFENMAFGLKLAKTPKEEIDRKVREAARVLQLEALLERRPKALSGGQRQRVAIGRAIVRQPGVF 156
Cdd:PRK13648 85 IGIVFQNpDNQFVGSIVKYDVAFGLENHAVPYDEMHRRVSEALKQVDMLERADYEPNALSGGQKQRVAIAGVLALNPSVI 164
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 928002514 157 LFDEPLSNLDATLRgQTRIEIARLHKQFAKASVVYVTHDQIEAMTlADKIVLLHAGKdterygsIAQIGAPLELY 231
Cdd:PRK13648 165 ILDEATSMLDPDAR-QNLLDLVRKVKSEHNITIISITHDLSEAME-ADHVIVMNKGT-------VYKEGTPTEIF 230
|
|
| cbiO |
PRK13646 |
energy-coupling factor transporter ATPase; |
3-231 |
2.52e-21 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184205 [Multi-domain] Cd Length: 286 Bit Score: 92.92 E-value: 2.52e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 3 SISLRGVQKAYGDGAP----VIRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLSIGG-KIMNDV------ 71
Cdd:PRK13646 2 TIRFDNVSYTYQKGTPyehqAIHDVNTEFEQGKYYAIVGQTGSGKSTLIQNINALLKPTTGTVTVDDiTITHKTkdkyir 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 72 PAAQRgVAMVFQsyalFPHMTVFEN-----MAFGLKLAKTPKEEidrkVREAARVLQLEA-----LLERRPKALSGGQRQ 141
Cdd:PRK13646 82 PVRKR-IGMVFQ----FPESQLFEDtvereIIFGPKNFKMNLDE----VKNYAHRLLMDLgfsrdVMSQSPFQMSGGQMR 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 142 RVAIGRAIVRQPGVFLFDEPLSNLDAtlrgQTRIEIARLHKQFA---KASVVYVTHDQIEAMTLADKIVLLhagkdteRY 218
Cdd:PRK13646 153 KIAIVSILAMNPDIIVLDEPTAGLDP----QSKRQVMRLLKSLQtdeNKTIILVSHDMNEVARYADEVIVM-------KE 221
|
250
....*....|...
gi 928002514 219 GSIAQIGAPLELY 231
Cdd:PRK13646 222 GSIVSQTSPKELF 234
|
|
| MsbA_lipidA |
TIGR02203 |
lipid A export permease/ATP-binding protein MsbA; This family consists of a single polypeptide ... |
4-217 |
2.81e-21 |
|
lipid A export permease/ATP-binding protein MsbA; This family consists of a single polypeptide chain transporter in the ATP-binding cassette (ABC) transporter family, MsbA, which exports lipid A. It may also act in multidrug resistance. Lipid A, a part of lipopolysaccharide, is found in the outer leaflet of the outer membrane of most Gram-negative bacteria. Members of this family are restricted to the Proteobacteria (although lipid A is more broadly distributed) and often are clustered with lipid A biosynthesis genes. [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides, Transport and binding proteins, Other]
Pssm-ID: 131258 [Multi-domain] Cd Length: 571 Bit Score: 95.55 E-value: 2.81e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 4 ISLRGVQKAY-GDGAPVIRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLSIGGKIMNDVPAA--QRGVAM 80
Cdd:TIGR02203 331 VEFRNVTFRYpGRDRPALDSISLVIEPGETVALVGRSGSGKSTLVNLIPRFYEPDSGQILLDGHDLADYTLAslRRQVAL 410
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 81 VFQSYALFPHmTVFENMAFGlKLAKTPKEEIdrkvREAARVLQLEALLERRPKA-----------LSGGQRQRVAIGRAI 149
Cdd:TIGR02203 411 VSQDVVLFND-TIANNIAYG-RTEQADRAEI----ERALAAAYAQDFVDKLPLGldtpigengvlLSGGQRQRLAIARAL 484
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 928002514 150 VRQPGVFLFDEPLSNLDATLRGQTRIEIARLHKQfaKASVVyVTHdQIEAMTLADKIVLLHAGKDTER 217
Cdd:TIGR02203 485 LKDAPILILDEATSALDNESERLVQAALERLMQG--RTTLV-IAH-RLSTIEKADRIVVMDDGRIVER 548
|
|
| ArpD |
COG4618 |
ABC-type protease/lipase transport system, ATPase and permease components [Intracellular ... |
2-213 |
3.07e-21 |
|
ABC-type protease/lipase transport system, ATPase and permease components [Intracellular trafficking, secretion, and vesicular transport];
Pssm-ID: 443660 [Multi-domain] Cd Length: 563 Bit Score: 95.20 E-value: 3.07e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 2 ASISLRGVQKAY-GDGAPVIRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLSIGGKIMNDVPAAQRG--V 78
Cdd:COG4618 329 GRLSVENLTVVPpGSKRPILRGVSFSLEPGEVLGVIGPSGSGKSTLARLLVGVWPPTAGSVRLDGADLSQWDREELGrhI 408
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 79 AMVFQSYALFPHmTVFENMA-FGlklaktpkEEIDRKVREAARVLQLEALLERRPK-----------ALSGGQRQRVAIG 146
Cdd:COG4618 409 GYLPQDVELFDG-TIAENIArFG--------DADPEKVVAAAKLAGVHEMILRLPDgydtrigeggaRLSGGQRQRIGLA 479
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 928002514 147 RAIVRQPGVFLFDEPLSNLDAT----LRGQtrieIARLHKQfaKASVVYVTHDQiEAMTLADKIVLLHAGK 213
Cdd:COG4618 480 RALYGDPRLVVLDEPNSNLDDEgeaaLAAA----IRALKAR--GATVVVITHRP-SLLAAVDKLLVLRDGR 543
|
|
| cbiO |
PRK13638 |
energy-coupling factor ABC transporter ATP-binding protein; |
13-242 |
3.72e-21 |
|
energy-coupling factor ABC transporter ATP-binding protein;
Pssm-ID: 184198 [Multi-domain] Cd Length: 271 Bit Score: 91.99 E-value: 3.72e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 13 YGDgAPVIRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLSIGGKIMN----DVPAAQRGVAMVFQSyalf 88
Cdd:PRK13638 11 YQD-EPVLKGLNLDFSLSPVTGLVGANGCGKSTLFMNLSGLLRPQKGAVLWQGKPLDyskrGLLALRQQVATVFQD---- 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 89 PHMTVF-----ENMAFGLKLAKTPKEEIDRKVREAARVLQLEALLERRPKALSGGQRQRVAIGRAIVRQPGVFLFDEPLS 163
Cdd:PRK13638 86 PEQQIFytdidSDIAFSLRNLGVPEAEITRRVDEALTLVDAQHFRHQPIQCLSHGQKKRVAIAGALVLQARYLLLDEPTA 165
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 928002514 164 NLDATLRGQTRIEIARLHKQfaKASVVYVTHDQIEAMTLADKIVLLhagkdteRYGSIAQIGAPLELYHRPKSRFVAGF 242
Cdd:PRK13638 166 GLDPAGRTQMIAIIRRIVAQ--GNHVIISSHDIDLIYEISDAVYVL-------RQGQILTHGAPGEVFACTEAMEQAGL 235
|
|
| bacteriocin_ABC |
TIGR01193 |
ABC-type bacteriocin transporter; This model describes ABC-type bacteriocin transporter. The ... |
3-232 |
4.32e-21 |
|
ABC-type bacteriocin transporter; This model describes ABC-type bacteriocin transporter. The amino terminal domain (pfam03412) processes the N-terminal leader peptide from the bacteriocin while C-terminal domains resemble ABC transporter membrane protein and ATP-binding cassette domain. In general, bacteriocins are agents which are responsible for killing or inhibiting the closely related species or even different strains of the same species. Bacteriocins are usually encoded by bacterial plasmids. Bacteriocins are named after the species and hence in literature one encounters various names e.g., leucocin from Leuconostic geldium; pedicocin from Pedicoccus acidilactici; sakacin from Lactobacillus sake etc. [Protein fate, Protein and peptide secretion and trafficking, Protein fate, Protein modification and repair, Transport and binding proteins, Other]
Pssm-ID: 130261 [Multi-domain] Cd Length: 708 Bit Score: 95.19 E-value: 4.32e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 3 SISLRGVQKAYGDGAPVIRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLSIGGKIMNDVP--AAQRGVAM 80
Cdd:TIGR01193 473 DIVINDVSYSYGYGSNILSDISLTIKMNSKTTIVGMSGSGKSTLAKLLVGFFQARSGEILLNGFSLKDIDrhTLRQFINY 552
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 81 VFQSYALFPHmTVFENMAFGLKlaktPKEEIDrKVREAARVLQLEALLERRPKA-----------LSGGQRQRVAIGRAI 149
Cdd:TIGR01193 553 LPQEPYIFSG-SILENLLLGAK----ENVSQD-EIWAACEIAEIKDDIENMPLGyqtelseegssISGGQKQRIALARAL 626
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 150 VRQPGVFLFDEPLSNLDATLrgQTRIeIARLHKQFAKaSVVYVTHdQIEAMTLADKIVLLHAGKDTERyGS----IAQIG 225
Cdd:TIGR01193 627 LTDSKVLILDESTSNLDTIT--EKKI-VNNLLNLQDK-TIIFVAH-RLSVAKQSDKIIVLDHGKIIEQ-GShdelLDRNG 700
|
....*..
gi 928002514 226 APLELYH 232
Cdd:TIGR01193 701 FYASLIH 707
|
|
| anch_rpt_ABC |
TIGR03771 |
anchored repeat-type ABC transporter, ATP-binding subunit; This protein family is the ... |
25-230 |
5.20e-21 |
|
anchored repeat-type ABC transporter, ATP-binding subunit; This protein family is the ATP-binding cassette subunit of binding protein-dependent ABC transporter complex that strictly co-occurs with TIGR03769. TIGRFAMs model TIGR03769 describes a protein domain that occurs singly or as one of up to three repeats in proteins of a number of Actinobacteria, including Propionibacterium acnes KPA171202. The TIGR03769 domain occurs both in an adjacent gene for the substrate-binding protein and in additional (often nearby) proteins, often with LPXTG-like sortase recognition signals. Homologous ATP-binding subunits outside the scope of this family include manganese transporter MntA in Synechocystis sp. PCC 6803 and chelated iron transporter subunits. The function of this transporter complex is unknown. [Transport and binding proteins, Unknown substrate]
Pssm-ID: 163483 [Multi-domain] Cd Length: 223 Bit Score: 90.30 E-value: 5.20e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 25 LEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLSIGGKimnDVPAAQRGVAMVFQSYAL---FP---HMTVFENMA 98
Cdd:TIGR03771 1 LSADKGELLGLLGPNGAGKTTLLRAILGLIPPAKGTVKVAGA---SPGKGWRHIGYVPQRHEFawdFPisvAHTVMSGRT 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 99 FGLKLAKTPKEEIDRKVREAARVLQLEALLERRPKALSGGQRQRVAIGRAIVRQPGVFLFDEPLSNLD---ATLRGQTRI 175
Cdd:TIGR03771 78 GHIGWLRRPCVADFAAVRDALRRVGLTELADRPVGELSGGQRQRVLVARALATRPSVLLLDEPFTGLDmptQELLTELFI 157
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 928002514 176 EIARlhkqfAKASVVYVTHDQIEAMTLADKIVLLHagkdteryGSIAQIGAPLEL 230
Cdd:TIGR03771 158 ELAG-----AGTAILMTTHDLAQAMATCDRVVLLN--------GRVIADGTPQQL 199
|
|
| PRK11160 |
PRK11160 |
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed |
2-233 |
6.60e-21 |
|
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed
Pssm-ID: 236865 [Multi-domain] Cd Length: 574 Bit Score: 94.12 E-value: 6.60e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 2 ASISLRGVQKAYGDGA-PVIRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLSIGGKIMNDVPAAQ--RGV 78
Cdd:PRK11160 337 VSLTLNNVSFTYPDQPqPVLKGLSLQIKAGEKVALLGRTGCGKSTLLQLLTRAWDPQQGEILLNGQPIADYSEAAlrQAI 416
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 79 AMVFQSYALFPHmTVFENmafgLKLAKtpKEEIDRKVREAARVLQLEALLER------------RPkaLSGGQRQRVAIG 146
Cdd:PRK11160 417 SVVSQRVHLFSA-TLRDN----LLLAA--PNASDEALIEVLQQVGLEKLLEDdkglnawlgeggRQ--LSGGEQRRLGIA 487
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 147 RAIVRQPGVFLFDEPLSNLDAtlrgQTRIEIARLHKQFAK-ASVVYVTHdQIEAMTLADKIVLLHAGKDTErYGS----I 221
Cdd:PRK11160 488 RALLHDAPLLLLDEPTEGLDA----ETERQILELLAEHAQnKTVLMITH-RLTGLEQFDRICVMDNGQIIE-QGThqelL 561
|
250
....*....|..
gi 928002514 222 AQIGAPLELYHR 233
Cdd:PRK11160 562 AQQGRYYQLKQR 573
|
|
| cbiO |
PRK13641 |
energy-coupling factor transporter ATPase; |
3-213 |
6.96e-21 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 237456 [Multi-domain] Cd Length: 287 Bit Score: 91.43 E-value: 6.96e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 3 SISLRGVQKAYGDGAPV----IRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLSIGGKIMN------DVP 72
Cdd:PRK13641 2 SIKFENVDYIYSPGTPMekkgLDNISFELEEGSFVALVGHTGSGKSTLMQHFNALLKPSSGTITIAGYHITpetgnkNLK 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 73 AAQRGVAMVFQsyalFPHMTVFEN-----MAFG-LKLAKTPKEEIDRKVREAARVLQLEALLERRPKALSGGQRQRVAIG 146
Cdd:PRK13641 82 KLRKKVSLVFQ----FPEAQLFENtvlkdVEFGpKNFGFSEDEAKEKALKWLKKVGLSEDLISKSPFELSGGQMRRVAIA 157
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 928002514 147 RAIVRQPGVFLFDEPLSNLDAtlrgQTRIEIARLHKQFAKA--SVVYVTHDQIEAMTLADKIVLLHAGK 213
Cdd:PRK13641 158 GVMAYEPEILCLDEPAAGLDP----EGRKEMMQLFKDYQKAghTVILVTHNMDDVAEYADDVLVLEHGK 222
|
|
| cbiO |
PRK13636 |
cobalt transporter ATP-binding subunit; Provisional |
4-213 |
1.07e-20 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 184196 [Multi-domain] Cd Length: 283 Bit Score: 91.06 E-value: 1.07e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 4 ISLRGVQKAYGDGAPVIRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLSIGGK--------IMNdvpaAQ 75
Cdd:PRK13636 6 LKVEELNYNYSDGTHALKGININIKKGEVTAILGGNGAGKSTLFQNLNGILKPSSGRILFDGKpidysrkgLMK----LR 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 76 RGVAMVFQS--YALFPhMTVFENMAFGLKLAKTPKEEIDRKVREAARVLQLEALLERRPKALSGGQRQRVAIGRAIVRQP 153
Cdd:PRK13636 82 ESVGMVFQDpdNQLFS-ASVYQDVSFGAVNLKLPEDEVRKRVDNALKRTGIEHLKDKPTHCLSFGQKKRVAIAGVLVMEP 160
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 928002514 154 GVFLFDEPLSNLDAtlRGQTriEIARLHKQFAKA---SVVYVTHDqIEAMTL-ADKIVLLHAGK 213
Cdd:PRK13636 161 KVLVLDEPTAGLDP--MGVS--EIMKLLVEMQKElglTIIIATHD-IDIVPLyCDNVFVMKEGR 219
|
|
| cbiO |
PRK13640 |
energy-coupling factor transporter ATPase; |
4-234 |
1.54e-20 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184200 [Multi-domain] Cd Length: 282 Bit Score: 90.63 E-value: 1.54e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 4 ISLRGVQKAYGDG-APVIRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGL---EDLTDGDLSIGG-----KIMNDVpaa 74
Cdd:PRK13640 6 VEFKHVSFTYPDSkKPALNDISFSIPRGSWTALIGHNGSGKSTISKLINGLllpDDNPNSKITVDGitltaKTVWDI--- 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 75 QRGVAMVFQSY-ALFPHMTVFENMAFGLKLAKTPKEEIDRKVREAARVLQLEALLERRPKALSGGQRQRVAIGRAIVRQP 153
Cdd:PRK13640 83 REKVGIVFQNPdNQFVGATVGDDVAFGLENRAVPRPEMIKIVRDVLADVGMLDYIDSEPANLSGGQKQRVAIAGILAVEP 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 154 GVFLFDEPLSNLDATLRGQTrIEIARLHKQFAKASVVYVTHDqIEAMTLADKIVLLHAGKdterygSIAQiGAPLELYHR 233
Cdd:PRK13640 163 KIIILDESTSMLDPAGKEQI-LKLIRKLKKKNNLTVISITHD-IDEANMADQVLVLDDGK------LLAQ-GSPVEIFSK 233
|
.
gi 928002514 234 P 234
Cdd:PRK13640 234 V 234
|
|
| ABC_NatA_like |
cd03267 |
ATP-binding cassette domain of an uncharacterized transporter similar in sequence to NatA; ... |
5-213 |
2.63e-20 |
|
ATP-binding cassette domain of an uncharacterized transporter similar in sequence to NatA; NatA is the ATPase component of a bacterial ABC-type Na+ transport system called NatAB, which catalyzes ATP-dependent electrogenic Na+ extrusion without mechanically coupled to proton or K+ uptake. NatB possess six putative membrane spanning regions at its C-terminus. In B. subtilis, NatAB is inducible by agents such as ethanol and protonophores, which lower the proton-motive force across the membrane. The closest sequence similarity to NatA is exhibited by DrrA of the two-component daunorubicin- and doxorubicin-efflux system. Hence, the functional NatAB is presumably assembled with two copies of the single ATP-binding protein and the single integral membrane protein.
Pssm-ID: 213234 [Multi-domain] Cd Length: 236 Bit Score: 88.93 E-value: 2.63e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 5 SLRGVQKAYGDGAPVIRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLSIGGKimndVPAAQRG-----VA 79
Cdd:cd03267 22 SLKSLFKRKYREVEALKGISFTIEKGEIVGFIGPNGAGKTTTLKILSGLLQPTSGEVRVAGL----VPWKRRKkflrrIG 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 80 MVF-QSYALFPHMTVFENMAFGLKLAKTPKEEIDRKVREAARVLQLEALLERRPKALSGGQRQRVAIGRAIVRQPGVFLF 158
Cdd:cd03267 98 VVFgQKTQLWWDLPVIDSFYLLAAIYDLPPARFKKRLDELSELLDLEELLDTPVRQLSLGQRMRAEIAAALLHEPEILFL 177
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 928002514 159 DEPLSNLDATLRGQTRIEIARLHKQFaKASVVYVTHD--QIEAmtLADKIVLLHAGK 213
Cdd:cd03267 178 DEPTIGLDVVAQENIRNFLKEYNRER-GTTVLLTSHYmkDIEA--LARRVLVIDKGR 231
|
|
| Uup |
COG0488 |
ATPase components of ABC transporters with duplicated ATPase domains [General function ... |
4-221 |
4.13e-20 |
|
ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only];
Pssm-ID: 440254 [Multi-domain] Cd Length: 520 Bit Score: 91.66 E-value: 4.13e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 4 ISLRGVQKAYGDgAPVIRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLSIGGKimndvpaaqrgvamVFQ 83
Cdd:COG0488 316 LELEGLSKSYGD-KTLLDDLSLRIDRGDRIGLIGPNGAGKSTLLKLLAGELEPDSGTVKLGET--------------VKI 380
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 84 SY------ALFPHMTVFENMafglklaktpkeeidRKVREAARVLQLEALLER----------RPKALSGGQRQRVAIGR 147
Cdd:COG0488 381 GYfdqhqeELDPDKTVLDEL---------------RDGAPGGTEQEVRGYLGRflfsgddafkPVGVLSGGEKARLALAK 445
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 928002514 148 AIVRQPGVFLFDEPLSNLDAtlrgQTRIEIARLHKQFaKASVVYVTHDQ--IEamTLADKIVLLHAGKDTERYGSI 221
Cdd:COG0488 446 LLLSPPNVLLLDEPTNHLDI----ETLEALEEALDDF-PGTVLLVSHDRyfLD--RVATRILEFEDGGVREYPGGY 514
|
|
| cbiO |
PRK13631 |
cobalt transporter ATP-binding subunit; Provisional |
19-231 |
4.66e-20 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 237451 [Multi-domain] Cd Length: 320 Bit Score: 89.91 E-value: 4.66e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 19 VIRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGL-----EDLTDGDLSIGGKIMNDVPAA-------------QRGVAM 80
Cdd:PRK13631 41 ALNNISYTFEKNKIYFIIGNSGSGKSTLVTHFNGLikskyGTIQVGDIYIGDKKNNHELITnpyskkiknfkelRRRVSM 120
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 81 VFQ--SYALFPHmTVFENMAFGLKLAKTPKEEIDRKVREAARVLQL-EALLERRPKALSGGQRQRVAIGRAIVRQPGVFL 157
Cdd:PRK13631 121 VFQfpEYQLFKD-TIEKDIMFGPVALGVKKSEAKKLAKFYLNKMGLdDSYLERSPFGLSGGQKRRVAIAGILAIQPEILI 199
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 928002514 158 FDEPLSNLDAtlRGQTriEIARLHKQfAKAS---VVYVTHDQIEAMTLADKIVLLHAGKdterygsIAQIGAPLELY 231
Cdd:PRK13631 200 FDEPTAGLDP--KGEH--EMMQLILD-AKANnktVFVITHTMEHVLEVADEVIVMDKGK-------ILKTGTPYEIF 264
|
|
| PRK15439 |
PRK15439 |
autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional |
4-212 |
5.44e-20 |
|
autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional
Pssm-ID: 185336 [Multi-domain] Cd Length: 510 Bit Score: 91.27 E-value: 5.44e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 4 ISLRGVQKAYGdGAPVIRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLSIGGKI---MNDVPAAQRGVAM 80
Cdd:PRK15439 12 LCARSISKQYS-GVEVLKGIDFTLHAGEVHALLGGNGAGKSTLMKIIAGIVPPDSGTLEIGGNPcarLTPAKAHQLGIYL 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 81 VFQSYALFPHMTVFENMAFGlkLAKTPKEEidRKVREAARVLQLEALLERRPKALSGGQRQRVAIGRAIVRQPGVFLFDE 160
Cdd:PRK15439 91 VPQEPLLFPNLSVKENILFG--LPKRQASM--QKMKQLLAALGCQLDLDSSAGSLEVADRQIVEILRGLMRDSRILILDE 166
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 928002514 161 PLSNLdatlrgqTRIEIARLHKQFAK-----ASVVYVTHDQIEAMTLADKIVLLHAG 212
Cdd:PRK15439 167 PTASL-------TPAETERLFSRIREllaqgVGIVFISHKLPEIRQLADRISVMRDG 216
|
|
| livF |
PRK11614 |
high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivF; |
1-213 |
7.62e-20 |
|
high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivF;
Pssm-ID: 183231 [Multi-domain] Cd Length: 237 Bit Score: 87.63 E-value: 7.62e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 1 MASISLRGVQKAYGDgAPVIRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLSIGGKIMNDVPAAQ---RG 77
Cdd:PRK11614 3 KVMLSFDKVSAHYGK-IQALHEVSLHINQGEIVTLIGANGAGKTTLLGTLCGDPRATSGRIVFDGKDITDWQTAKimrEA 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 78 VAMVFQSYALFPHMTVFENMAFGLKLAKtpKEEIDRKVreaARVLQL-EALLERRPK---ALSGGQRQRVAIGRAIVRQP 153
Cdd:PRK11614 82 VAIVPEGRRVFSRMTVEENLAMGGFFAE--RDQFQERI---KWVYELfPRLHERRIQragTMSGGEQQMLAIGRALMSQP 156
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 154 GVFLFDEPLSNLDATLRGQTRIEIARLHKQfaKASVVYVTHDQIEAMTLADKIVLLHAGK 213
Cdd:PRK11614 157 RLLLLDEPSLGLAPIIIQQIFDTIEQLREQ--GMTIFLVEQNANQALKLADRGYVLENGH 214
|
|
| PRK13536 |
PRK13536 |
nodulation factor ABC transporter ATP-binding protein NodI; |
1-230 |
1.20e-19 |
|
nodulation factor ABC transporter ATP-binding protein NodI;
Pssm-ID: 237419 [Multi-domain] Cd Length: 340 Bit Score: 88.73 E-value: 1.20e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 1 MASISLRGVQKAYGDgAPVIRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLSI-GGKIMNDVPAAQRGVA 79
Cdd:PRK13536 39 TVAIDLAGVSKSYGD-KAVVNGLSFTVASGECFGLLGPNGAGKSTIARMILGMTSPDAGKITVlGVPVPARARLARARIG 117
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 80 MVFQSYALFPHMTVFENMA-----FGLKLAKTpkEEIDRKVREAARvlqLEALLERRPKALSGGQRQRVAIGRAIVRQPG 154
Cdd:PRK13536 118 VVPQFDNLDLEFTVRENLLvfgryFGMSTREI--EAVIPSLLEFAR---LESKADARVSDLSGGMKRRLTLARALINDPQ 192
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 928002514 155 VFLFDEPLSNLDATLRgqtRIEIARLHKQFAKA-SVVYVTHDQIEAMTLADKIVLLHAGKdterygSIAQiGAPLEL 230
Cdd:PRK13536 193 LLILDEPTTGLDPHAR---HLIWERLRSLLARGkTILLTTHFMEEAERLCDRLCVLEAGR------KIAE-GRPHAL 259
|
|
| BtuD |
COG4138 |
ABC-type cobalamin transport system, ATPase component BtuD [Coenzyme transport and metabolism]; ... |
36-213 |
1.38e-19 |
|
ABC-type cobalamin transport system, ATPase component BtuD [Coenzyme transport and metabolism];
Pssm-ID: 443313 [Multi-domain] Cd Length: 248 Bit Score: 86.82 E-value: 1.38e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 36 LGPSGCGKSTLLCMIAGLEDlTDGDLSIGGKIMNDVPAAQ--RGVAMVFQSYALFPHMTVFENMAFGLKlAKTPKEEIDR 113
Cdd:COG4138 28 IGPNGAGKSTLLARMAGLLP-GQGEILLNGRPLSDWSAAElaRHRAYLSQQQSPPFAMPVFQYLALHQP-AGASSEAVEQ 105
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 114 KVREAARVLQLEALLERRPKALSGGQRQRVAIGrAIVRQ--PGV------FLFDEPLSNLDatlrgqtrieIA------R 179
Cdd:COG4138 106 LLAQLAEALGLEDKLSRPLTQLSGGEWQRVRLA-AVLLQvwPTInpegqlLLLDEPMNSLD----------VAqqaaldR 174
|
170 180 190
....*....|....*....|....*....|....*.
gi 928002514 180 LHKQFAKA--SVVYVTHDQIEAMTLADKIVLLHAGK 213
Cdd:COG4138 175 LLRELCQQgiTVVMSSHDLNHTLRHADRVWLLKQGK 210
|
|
| PRK13537 |
PRK13537 |
nodulation factor ABC transporter ATP-binding protein NodI; |
2-230 |
1.74e-19 |
|
nodulation factor ABC transporter ATP-binding protein NodI;
Pssm-ID: 237420 [Multi-domain] Cd Length: 306 Bit Score: 87.94 E-value: 1.74e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 2 ASISLRGVQKAYGDGApVIRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLSIGGK-IMNDVPAAQRGVAM 80
Cdd:PRK13537 6 APIDFRNVEKRYGDKL-VVDGLSFHVQRGECFGLLGPNGAGKTTTLRMLLGLTHPDAGSISLCGEpVPSRARHARQRVGV 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 81 VFQSYALFPHMTVFENMA-----FGLKLAktpkeEIDRKVREAARVLQLEALLERRPKALSGGQRQRVAIGRAIVRQPGV 155
Cdd:PRK13537 85 VPQFDNLDPDFTVRENLLvfgryFGLSAA-----AARALVPPLLEFAKLENKADAKVGELSGGMKRRLTLARALVNDPDV 159
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 928002514 156 FLFDEPLSNLDAtlrgQTRIEI-ARLHKQFAKA-SVVYVTHDQIEAMTLADKIVLLHAGKdterygSIAQiGAPLEL 230
Cdd:PRK13537 160 LVLDEPTTGLDP----QARHLMwERLRSLLARGkTILLTTHFMEEAERLCDRLCVIEEGR------KIAE-GAPHAL 225
|
|
| PRK10261 |
PRK10261 |
glutathione transporter ATP-binding protein; Provisional |
18-253 |
2.00e-19 |
|
glutathione transporter ATP-binding protein; Provisional
Pssm-ID: 182342 [Multi-domain] Cd Length: 623 Bit Score: 89.91 E-value: 2.00e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 18 PVIRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLSIGGKIM----------NDVPAAQ----RG--VAMV 81
Cdd:PRK10261 30 AAVRNLSFSLQRGETLAIVGESGSGKSVTALALMRLLEQAGGLVQCDKMLLrrrsrqvielSEQSAAQmrhvRGadMAMI 109
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 82 FQS--YALFPHMTVFENMAFGLKLAKTPKEEidRKVREAARVLQL------EALLERRPKALSGGQRQRVAIGRAIVRQP 153
Cdd:PRK10261 110 FQEpmTSLNPVFTVGEQIAESIRLHQGASRE--EAMVEAKRMLDQvripeaQTILSRYPHQLSGGMRQRVMIAMALSCRP 187
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 154 GVFLFDEPLSNLDATLRGQTRIEIARLHKQFAKAsVVYVTHDQIEAMTLADKIVLLHAGKDTERyGSIAQIgaplelYHR 233
Cdd:PRK10261 188 AVLIADEPTTALDVTIQAQILQLIKVLQKEMSMG-VIFITHDMGVVAEIADRVLVMYQGEAVET-GSVEQI------FHA 259
|
250 260
....*....|....*....|.
gi 928002514 234 PKSRFVAGFIGS-PRMNFLPG 253
Cdd:PRK10261 260 PQHPYTRALLAAvPQLGAMKG 280
|
|
| dppF |
PRK11308 |
dipeptide transporter ATP-binding subunit; Provisional |
37-233 |
3.08e-19 |
|
dipeptide transporter ATP-binding subunit; Provisional
Pssm-ID: 236898 [Multi-domain] Cd Length: 327 Bit Score: 87.33 E-value: 3.08e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 37 GPSGCGKSTLLCMIAGLEDLTDGDLSIGGKIMNDVPAAQ-----RGVAMVFQS-YA-LFPHMTV----FENMAFGLKLAK 105
Cdd:PRK11308 48 GESGCGKSTLARLLTMIETPTGGELYYQGQDLLKADPEAqkllrQKIQIVFQNpYGsLNPRKKVgqilEEPLLINTSLSA 127
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 106 TPKEEidrKVREA-ARV-LQLEALlERRPKALSGGQRQRVAIGRAIVRQPGVFLFDEPLSNLDATLRGQTRIEIARLHKQ 183
Cdd:PRK11308 128 AERRE---KALAMmAKVgLRPEHY-DRYPHMFSGGQRQRIAIARALMLDPDVVVADEPVSALDVSVQAQVLNLMMDLQQE 203
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 928002514 184 FaKASVVYVTHDQIEAMTLADKIVLLHAGKDTERyGSIAQI-GAPLELYHR 233
Cdd:PRK11308 204 L-GLSYVFISHDLSVVEHIADEVMVMYLGRCVEK-GTKEQIfNNPRHPYTQ 252
|
|
| PRK14271 |
PRK14271 |
phosphate ABC transporter ATP-binding protein; Provisional |
16-244 |
3.62e-19 |
|
phosphate ABC transporter ATP-binding protein; Provisional
Pssm-ID: 172759 [Multi-domain] Cd Length: 276 Bit Score: 86.69 E-value: 3.62e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 16 GAPVIRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDG-----DLSIGGK-IMN--DVPAAQRGVAMVFQSYAL 87
Cdd:PRK14271 33 GKTVLDQVSMGFPARAVTSLMGPTGSGKTTFLRTLNRMNDKVSGyrysgDVLLGGRsIFNyrDVLEFRRRVGMLFQRPNP 112
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 88 FPhMTVFENMAFGLKLAK-TPKEEIdRKVREA--ARVLQLEALLER---RPKALSGGQRQRVAIGRAIVRQPGVFLFDEP 161
Cdd:PRK14271 113 FP-MSIMDNVLAGVRAHKlVPRKEF-RGVAQArlTEVGLWDAVKDRlsdSPFRLSGGQQQLLCLARTLAVNPEVLLLDEP 190
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 162 LSNLDATlrgqTRIEIARLHKQFA-KASVVYVTHDQIEAMTLADKIVLLHAGKDTERygsiaqiGAPLELYHRPK----S 236
Cdd:PRK14271 191 TSALDPT----TTEKIEEFIRSLAdRLTVIIVTHNLAQAARISDRAALFFDGRLVEE-------GPTEQLFSSPKhaetA 259
|
....*...
gi 928002514 237 RFVAGFIG 244
Cdd:PRK14271 260 RYVAGLSG 267
|
|
| NHLM_micro_ABC1 |
TIGR03796 |
NHLM bacteriocin system ABC transporter, peptidase/ATP-binding protein; This protein describes ... |
4-217 |
3.78e-19 |
|
NHLM bacteriocin system ABC transporter, peptidase/ATP-binding protein; This protein describes a multidomain ABC transporter subunit that is one of three protein families associated with some regularity with a distinctive family of putative bacteriocins. It includes a bacteriocin-processing peptidase domain at the N-terminus. Model TIGR03793 describes a conserved propeptide region for this bacteriocin family, unusual because it shows obvious homology a region of the enzyme nitrile hydratase up to the classic Gly-Gly cleavage motif. This family is therefore predicted to be a subunit of a bacteriocin processing and export system characteristic to this system that we designate NHLM, Nitrile Hydratase Leader Microcin. [Transport and binding proteins, Amino acids, peptides and amines, Cellular processes, Biosynthesis of natural products]
Pssm-ID: 274788 [Multi-domain] Cd Length: 710 Bit Score: 89.23 E-value: 3.78e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 4 ISLRGVQKAYGD-GAPVIRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLSIGGKIMNDVP--AAQRGVAM 80
Cdd:TIGR03796 478 VELRNITFGYSPlEPPLIENFSLTLQPGQRVALVGGSGSGKSTIAKLVAGLYQPWSGEILFDGIPREEIPreVLANSVAM 557
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 81 VFQSYALFpHMTVFENMAfgLKLAKTPKEEIDRKVREAA-------RVLQLEALLERRPKALSGGQRQRVAIGRAIVRQP 153
Cdd:TIGR03796 558 VDQDIFLF-EGTVRDNLT--LWDPTIPDADLVRACKDAAihdvitsRPGGYDAELAEGGANLSGGQRQRLEIARALVRNP 634
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 928002514 154 GVFLFDEPLSNLDATL----------RGQTRIEIA-RLhkqfakaSVVyvtHDqieamtlADKIVLLHAGKDTER 217
Cdd:TIGR03796 635 SILILDEATSALDPETekiiddnlrrRGCTCIIVAhRL-------STI---RD-------CDEIIVLERGKVVQR 692
|
|
| PRK15112 |
PRK15112 |
peptide ABC transporter ATP-binding protein SapF; |
20-246 |
4.03e-19 |
|
peptide ABC transporter ATP-binding protein SapF;
Pssm-ID: 185067 [Multi-domain] Cd Length: 267 Bit Score: 86.00 E-value: 4.03e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 20 IRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLSIGGKIMN--DVPAAQRGVAMVFQ--SYALFPHMTVFE 95
Cdd:PRK15112 29 VKPLSFTLREGQTLAIIGENGSGKSTLAKMLAGMIEPTSGELLIDDHPLHfgDYSYRSQRIRMIFQdpSTSLNPRQRISQ 108
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 96 NMAFGLKLaKTPKEEIDRKVREAARVLQLEALLERR---PKALSGGQRQRVAIGRAIVRQPGVFLFDEPLSNLDATLRGQ 172
Cdd:PRK15112 109 ILDFPLRL-NTDLEPEQREKQIIETLRQVGLLPDHAsyyPHMLAPGQKQRLGLARALILRPKVIIADEALASLDMSMRSQ 187
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 928002514 173 TRIEIARLHKQFAkASVVYVTHDQIEAMTLADKIVLLHAGKDTERyGSIAQI-GAPLelyHRPKSRFVAGFIGSP 246
Cdd:PRK15112 188 LINLMLELQEKQG-ISYIYVTQHLGMMKHISDQVLVMHQGEVVER-GSTADVlASPL---HELTKRLIAGHFGEA 257
|
|
| YddA |
COG4178 |
ABC-type uncharacterized transport system, permease and ATPase components [General function ... |
2-194 |
4.14e-19 |
|
ABC-type uncharacterized transport system, permease and ATPase components [General function prediction only];
Pssm-ID: 443337 [Multi-domain] Cd Length: 571 Bit Score: 88.71 E-value: 4.14e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 2 ASISLRGVQKAYGDGAPVIRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLsiggkimnDVPAAQRgvaMV 81
Cdd:COG4178 361 GALALEDLTLRTPDGRPLLEDLSLSLKPGERLLITGPSGSGKSTLLRAIAGLWPYGSGRI--------ARPAGAR---VL 429
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 82 F---QSYalFPHMTVFENMAFglklAKTPKEEIDRKVREAARVLQLEALLER------RPKALSGGQRQRVAIGRAIVRQ 152
Cdd:COG4178 430 FlpqRPY--LPLGTLREALLY----PATAEAFSDAELREALEAVGLGHLAERldeeadWDQVLSLGEQQRLAFARLLLHK 503
|
170 180 190 200
....*....|....*....|....*....|....*....|..
gi 928002514 153 PGVFLFDEPLSNLDATLRGQTrieIARLHKQFAKASVVYVTH 194
Cdd:COG4178 504 PDWLFLDEATSALDEENEAAL---YQLLREELPGTTVISVGH 542
|
|
| ABC_KpsT_Wzt |
cd03220 |
ATP-binding cassette component of polysaccharide transport system; The KpsT/Wzt ABC ... |
19-213 |
5.15e-19 |
|
ATP-binding cassette component of polysaccharide transport system; The KpsT/Wzt ABC transporter subfamily is involved in extracellular polysaccharide export. Among the variety of membrane-linked or extracellular polysaccharides excreted by bacteria, only capsular polysaccharides, lipopolysaccharides, and teichoic acids have been shown to be exported by ABC transporters. A typical system is made of a conserved integral membrane and an ABC. In addition to these proteins, capsular polysaccharide exporter systems require two 'accessory' proteins to perform their function: a periplasmic (E.coli) or a lipid-anchored outer membrane protein called OMA (Neisseria meningitidis and Haemophilus influenza) and a cytoplasmic membrane protein MPA2.
Pssm-ID: 213187 [Multi-domain] Cd Length: 224 Bit Score: 84.89 E-value: 5.15e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 19 VIRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLSIGGKImndvpAAQRGVAMVFQsyalfPHMTVFENMA 98
Cdd:cd03220 37 ALKDVSFEVPRGERIGLIGRNGAGKSTLLRLLAGIYPPDSGTVTVRGRV-----SSLLGLGGGFN-----PELTGRENIY 106
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 99 FGLKLAKTPKEEIDRKVREAARVLQLEALLERRPKALSGGQRQRVAIGRAIVRQPGVFLFDEPLSNLDATLRGQTRIEIA 178
Cdd:cd03220 107 LNGRLLGLSRKEIDEKIDEIIEFSELGDFIDLPVKTYSSGMKARLAFAIATALEPDILLIDEVLAVGDAAFQEKCQRRLR 186
|
170 180 190
....*....|....*....|....*....|....*
gi 928002514 179 RLHKQfaKASVVYVTHDQIEAMTLADKIVLLHAGK 213
Cdd:cd03220 187 ELLKQ--GKTVILVSHDPSSIKRLCDRALVLEKGK 219
|
|
| rim_protein |
TIGR01257 |
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim ... |
16-213 |
1.38e-18 |
|
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim protein) in eukaryotes. It is the member of ABC transporter superfamily. Rim protein is a membrane glycoprotein which is localized in the photoreceptor outer segment discs. Mutation/s in its genetic loci is implicated in the recessive Stargardt's disease. [Transport and binding proteins, Other]
Pssm-ID: 130324 [Multi-domain] Cd Length: 2272 Bit Score: 88.15 E-value: 1.38e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 16 GAPVIRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLSIGGK-IMNDVPAAQRGVAMVFQSYALFPHMTVF 94
Cdd:TIGR01257 942 GRPAVDRLNITFYENQITAFLGHNGAGKTTTLSILTGLLPPTSGTVLVGGKdIETNLDAVRQSLGMCPQHNILFHHLTVA 1021
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 95 ENMAFGLKLAKTPKEEIDrkvreaarvLQLEALLE-------RRPKA--LSGGQRQRVAIGRAIVRQPGVFLFDEPLSNL 165
Cdd:TIGR01257 1022 EHILFYAQLKGRSWEEAQ---------LEMEAMLEdtglhhkRNEEAqdLSGGMQRKLSVAIAFVGDAKVVVLDEPTSGV 1092
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 928002514 166 DATLRgqtRIEIARLHKQFAKASVVYVTHDQIEAMTLADKIVLLHAGK 213
Cdd:TIGR01257 1093 DPYSR---RSIWDLLLKYRSGRTIIMSTHHMDEADLLGDRIAIISQGR 1137
|
|
| SufC |
COG0396 |
Fe-S cluster assembly ATPase SufC [Posttranslational modification, protein turnover, ... |
15-213 |
1.66e-18 |
|
Fe-S cluster assembly ATPase SufC [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 440165 [Multi-domain] Cd Length: 245 Bit Score: 83.96 E-value: 1.66e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 15 DGAPVIRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLED--LTDGDLSIGGKIMNDVPA---AQRGVAMVFQSYALFP 89
Cdd:COG0396 11 EGKEILKGVNLTIKPGEVHAIMGPNGSGKSTLAKVLMGHPKyeVTSGSILLDGEDILELSPderARAGIFLAFQYPVEIP 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 90 HMTVFEnmaFgLKLAKT--PKEEID-----RKVREAARVLQLEALLERRP--KALSGGQRQRVAIGRAIVRQPGVFLFDE 160
Cdd:COG0396 91 GVSVSN---F-LRTALNarRGEELSareflKLLKEKMKELGLDEDFLDRYvnEGFSGGEKKRNEILQMLLLEPKLAILDE 166
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 928002514 161 PLSNLDA-TLRGQTRIeIARLHKQfaKASVVYVTH-----DQIEamtlADKIVLLHAGK 213
Cdd:COG0396 167 TDSGLDIdALRIVAEG-VNKLRSP--DRGILIITHyqrilDYIK----PDFVHVLVDGR 218
|
|
| ABCC_TAP |
cd03248 |
ATP-binding cassette domain of the Transporter Associated with Antigen Processing, subfamily C; ... |
18-213 |
1.75e-18 |
|
ATP-binding cassette domain of the Transporter Associated with Antigen Processing, subfamily C; TAP (Transporter Associated with Antigen Processing) is essential for peptide delivery from the cytosol into the lumen of the endoplasmic reticulum (ER), where these peptides are loaded on major histocompatibility complex (MHC) I molecules. Loaded MHC I leave the ER and display their antigenic cargo on the cell surface to cytotoxic T cells. Subsequently, virus-infected or malignantly transformed cells can be eliminated. TAP belongs to the large family of ATP-binding cassette (ABC) transporters, which translocate a vast variety of solutes across membranes.
Pssm-ID: 213215 [Multi-domain] Cd Length: 226 Bit Score: 83.29 E-value: 1.75e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 18 PVIRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLSIGGKIMNDVPAA--QRGVAMVFQSYALFPHmTVFE 95
Cdd:cd03248 28 LVLQDVSFTLHPGEVTALVGPSGSGKSTVVALLENFYQPQGGQVLLDGKPISQYEHKylHSKVSLVGQEPVLFAR-SLQD 106
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 96 NMAFGLKLAKtpkeeiDRKVREAARVLQLEALLERRPKA-----------LSGGQRQRVAIGRAIVRQPGVFLFDEPLSN 164
Cdd:cd03248 107 NIAYGLQSCS------FECVKEAAQKAHAHSFISELASGydtevgekgsqLSGGQKQRVAIARALIRNPQVLILDEATSA 180
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 928002514 165 LDAtlrgQTRIEIARLHKQFAKASVVYVTHDQIEAMTLADKIVLLHAGK 213
Cdd:cd03248 181 LDA----ESEQQVQQALYDWPERRTVLVIAHRLSTVERADQILVLDGGR 225
|
|
| araG |
PRK11288 |
L-arabinose ABC transporter ATP-binding protein AraG; |
1-224 |
2.52e-18 |
|
L-arabinose ABC transporter ATP-binding protein AraG;
Pssm-ID: 183077 [Multi-domain] Cd Length: 501 Bit Score: 86.12 E-value: 2.52e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 1 MASISLRGVQKAYgDGAPVIRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLSIGGKIM---NDVPAAQRG 77
Cdd:PRK11288 2 SPYLSFDGIGKTF-PGVKALDDISFDCRAGQVHALMGENGAGKSTLLKILSGNYQPDAGSILIDGQEMrfaSTTAALAAG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 78 VAMVFQSYALFPHMTVFENmafgLKLAKTPKEE--IDRK--VREAARvlQLEALLER-----RPKALSGGQRQRVAIGRA 148
Cdd:PRK11288 81 VAIIYQELHLVPEMTVAEN----LYLGQLPHKGgiVNRRllNYEARE--QLEHLGVDidpdtPLKYLSIGQRQMVEIAKA 154
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 928002514 149 IVRQPGVFLFDEPLSNLDATLRGQTRIEIARLHKQfAKAsVVYVTHDQIEAMTLADKIVLLHAGKDTERYGSIAQI 224
Cdd:PRK11288 155 LARNARVIAFDEPTSSLSAREIEQLFRVIRELRAE-GRV-ILYVSHRMEEIFALCDAITVFKDGRYVATFDDMAQV 228
|
|
| ABC_RNaseL_inhibitor_domain2 |
cd03237 |
The ATP-binding cassette domain 2 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI) ... |
26-216 |
2.56e-18 |
|
The ATP-binding cassette domain 2 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI), is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI's are not transport proteins and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLI's have an N-terminal Fe-S domain and two nucleotide-binding domains which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity of more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.
Pssm-ID: 213204 [Multi-domain] Cd Length: 246 Bit Score: 83.61 E-value: 2.56e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 26 EIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDlsiggkimndVPAAQRGVAMVFQSYALFPHMTVFEnmafgLKLAK 105
Cdd:cd03237 21 SISESEVIGILGPNGIGKTTFIKMLAGVLKPDEGD----------IEIELDTVSYKPQYIKADYEGTVRD-----LLSSI 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 106 TPKEEIDRKVR-EAARVLQLEALLERRPKALSGGQRQRVAIGRAIVRQPGVFLFDEPLSNLDAtlrgQTRIEIARLHKQF 184
Cdd:cd03237 86 TKDFYTHPYFKtEIAKPLQIEQILDREVPELSGGELQRVAIAACLSKDADIYLLDEPSAYLDV----EQRLMASKVIRRF 161
|
170 180 190
....*....|....*....|....*....|....*..
gi 928002514 185 A---KASVVYVTHDQIEAMTLADKIVLL--HAGKDTE 216
Cdd:cd03237 162 AennEKTAFVVEHDIIMIDYLADRLIVFegEPSVNGV 198
|
|
| cbiO |
PRK13652 |
cobalt transporter ATP-binding subunit; Provisional |
1-273 |
2.72e-18 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 172200 [Multi-domain] Cd Length: 277 Bit Score: 84.08 E-value: 2.72e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 1 MASISLRGVQKAYGDGAPVIRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLSIGGKIMN--DVPAAQRGV 78
Cdd:PRK13652 1 MHLIETRDLCYSYSGSKEALNNINFIAPRNSRIAVIGPNGAGKSTLFRHFNGILKPTSGSVLIRGEPITkeNIREVRKFV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 79 AMVFQSY--ALFPhMTVFENMAFGLKLAKTPKEEIDRKVREAARVLQLEALLERRPKALSGGQRQRVAIGRAIVRQPGVF 156
Cdd:PRK13652 81 GLVFQNPddQIFS-PTVEQDIAFGPINLGLDEETVAHRVSSALHMLGLEELRDRVPHHLSGGEKKRVAIAGVIAMEPQVL 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 157 LFDEPLSNLDATLRGQTRIEIARLHKQFAkASVVYVTHDQIEAMTLADKIVLLHAgkdteryGSIAQIGAPLELYHRPKs 236
Cdd:PRK13652 160 VLDEPTAGLDPQGVKELIDFLNDLPETYG-MTVIFSTHQLDLVPEMADYIYVMDK-------GRIVAYGTVEEIFLQPD- 230
|
250 260 270
....*....|....*....|....*....|....*....
gi 928002514 237 rfvagFIGSPRMNF--LPGRVASVDAQGVIVTLDTTLEN 273
Cdd:PRK13652 231 -----LLARVHLDLpsLPKLIRSLQAQGIAIDMAYTYQE 264
|
|
| ABCC_cytochrome_bd |
cd03247 |
ATP-binding cassette domain of CydCD, subfamily C; The CYD subfamily implicated in cytochrome ... |
4-216 |
3.60e-18 |
|
ATP-binding cassette domain of CydCD, subfamily C; The CYD subfamily implicated in cytochrome bd biogenesis. The CydC and CydD proteins are important for the formation of cytochrome bd terminal oxidase of E. coli and it has been proposed that they were necessary for biosynthesis of the cytochrome bd quinol oxidase and for periplasmic c-type cytochromes. CydCD were proposed to determine a heterooligomeric complex important for heme export into the periplasm or to be involved in the maintenance of the proper redox state of the periplasmic space. In Bacillus subtilis, the absence of CydCD does not affect the presence of halo-cytochrome c in the membrane and this observation suggests that CydCD proteins are not involved in the export of heme in this organism.
Pssm-ID: 213214 [Multi-domain] Cd Length: 178 Bit Score: 81.21 E-value: 3.60e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 4 ISLRGVQKAYGD-GAPVIRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLSIGGKIMNDVPAAQRG-VAMV 81
Cdd:cd03247 1 LSINNVSFSYPEqEQQVLKNLSLELKQGEKIALLGRSGSGKSTLLQLLTGDLKPQQGEITLDGVPVSDLEKALSSlISVL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 82 FQSYALFpHMTVFENmafglklaktpkeeidrkvreaarvlqlealLERRpkaLSGGQRQRVAIGRAIVRQPGVFLFDEP 161
Cdd:cd03247 81 NQRPYLF-DTTLRNN-------------------------------LGRR---FSGGERQRLALARILLQDAPIVLLDEP 125
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 928002514 162 LSNLDATlrgqTRIEIARLHKQFAK-ASVVYVTHdQIEAMTLADKIVLLHAGKDTE 216
Cdd:cd03247 126 TVGLDPI----TERQLLSLIFEVLKdKTLIWITH-HLTGIEHMDKILFLENGKIIM 176
|
|
| PRK10895 |
PRK10895 |
lipopolysaccharide ABC transporter ATP-binding protein; Provisional |
1-166 |
3.88e-18 |
|
lipopolysaccharide ABC transporter ATP-binding protein; Provisional
Pssm-ID: 182817 [Multi-domain] Cd Length: 241 Bit Score: 83.02 E-value: 3.88e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 1 MASISLRGVQKAYgDGAPVIRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLSIGGKIMNDVP---AAQRG 77
Cdd:PRK10895 1 MATLTAKNLAKAY-KGRRVVEDVSLTVNSGEIVGLLGPNGAGKTTTFYMVVGIVPRDAGNIIIDDEDISLLPlhaRARRG 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 78 VAMVFQSYALFPHMTVFENMAFGLKLAKT-PKEEIDRKVREAARVLQLEALLERRPKALSGGQRQRVAIGRAIVRQPGVF 156
Cdd:PRK10895 80 IGYLPQEASIFRRLSVYDNLMAVLQIRDDlSAEQREDRANELMEEFHIEHLRDSMGQSLSGGERRRVEIARALAANPKFI 159
|
170
....*....|
gi 928002514 157 LFDEPLSNLD 166
Cdd:PRK10895 160 LLDEPFAGVD 169
|
|
| PRK13651 |
PRK13651 |
cobalt transporter ATP-binding subunit; Provisional |
4-213 |
5.81e-18 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 184210 [Multi-domain] Cd Length: 305 Bit Score: 83.60 E-value: 5.81e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 4 ISLRGVQKAYGDGAP----VIRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDL------------------ 61
Cdd:PRK13651 3 IKVKNIVKIFNKKLPtelkALDNVSVEINQGEFIAIIGQTGSGKTTFIEHLNALLLPDTGTIewifkdeknkkktkekek 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 62 ---------SIGGKIMNdVPAAQRGVAMVFQ--SYALFpHMTVFENMAFGLKLAKTPKEEIDRKVREAARVLQL-EALLE 129
Cdd:PRK13651 83 vleklviqkTRFKKIKK-IKEIRRRVGVVFQfaEYQLF-EQTIEKDIIFGPVSMGVSKEEAKKRAAKYIELVGLdESYLQ 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 130 RRPKALSGGQRQRVAIGRAIVRQPGVFLFDEPLSNLDAtlrgQTRIEI----ARLHKQfaKASVVYVTHDQIEAMTLADK 205
Cdd:PRK13651 161 RSPFELSGGQKRRVALAGILAMEPDFLVFDEPTAGLDP----QGVKEIleifDNLNKQ--GKTIILVTHDLDNVLEWTKR 234
|
....*...
gi 928002514 206 IVLLHAGK 213
Cdd:PRK13651 235 TIFFKDGK 242
|
|
| type_I_sec_HlyB |
TIGR01846 |
type I secretion system ABC transporter, HlyB family; Type I protein secretion is a system in ... |
3-216 |
7.22e-18 |
|
type I secretion system ABC transporter, HlyB family; Type I protein secretion is a system in some Gram-negative bacteria to export proteins (often proteases) across both inner and outer membranes to the extracellular medium. This is one of three proteins of the type I secretion apparatus. Targeted proteins are not cleaved at the N-terminus, but rather carry signals located toward the extreme C-terminus to direct type I secretion. [Protein fate, Protein and peptide secretion and trafficking]
Pssm-ID: 273831 [Multi-domain] Cd Length: 694 Bit Score: 85.18 E-value: 7.22e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 3 SISLRGVQKAYG-DGAPVIRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGL------EDLTDG-DLSIGgkimnDVPAA 74
Cdd:TIGR01846 455 AITFENIRFRYApDSPEVLSNLNLDIKPGEFIGIVGPSGSGKSTLTKLLQRLytpqhgQVLVDGvDLAIA-----DPAWL 529
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 75 QRGVAMVFQSYALFPHmTVFENMAFGLKLAKtpkeeiDRKVREAARVLQLEALLERRPK-----------ALSGGQRQRV 143
Cdd:TIGR01846 530 RRQMGVVLQENVLFSR-SIRDNIALCNPGAP------FEHVIHAAKLAGAHDFISELPQgyntevgekgaNLSGGQRQRI 602
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 928002514 144 AIGRAIVRQPGVFLFDEPLSNLDATlrgQTRIEIARLHKQFAKASVVYVTHdQIEAMTLADKIVLLHAGKDTE 216
Cdd:TIGR01846 603 AIARALVGNPRILIFDEATSALDYE---SEALIMRNMREICRGRTVIIIAH-RLSTVRACDRIIVLEKGQIAE 671
|
|
| 3a01208 |
TIGR00958 |
Conjugate Transporter-2 (CT2) Family protein; [Transport and binding proteins, Other] |
18-234 |
8.14e-18 |
|
Conjugate Transporter-2 (CT2) Family protein; [Transport and binding proteins, Other]
Pssm-ID: 273363 [Multi-domain] Cd Length: 711 Bit Score: 85.16 E-value: 8.14e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 18 PVIRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLSIGGkimndVPAAQ-------RGVAMVFQSYALFPH 90
Cdd:TIGR00958 495 PVLKGLTFTLHPGEVVALVGPSGSGKSTVAALLQNLYQPTGGQVLLDG-----VPLVQydhhylhRQVALVGQEPVLFSG 569
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 91 mTVFENMAFGLKlaKTPKEEIdrkvREAARVLQLEALLERRPKA-----------LSGGQRQRVAIGRAIVRQPGVFLFD 159
Cdd:TIGR00958 570 -SVRENIAYGLT--DTPDEEI----MAAAKAANAHDFIMEFPNGydtevgekgsqLSGGQKQRIAIARALVRKPRVLILD 642
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 928002514 160 EPLSNLDAtlrgqtriEIARLHKQ---FAKASVVYVTHdQIEAMTLADKIVLLhagkdteRYGSIAQIGAPLELYHRP 234
Cdd:TIGR00958 643 EATSALDA--------ECEQLLQEsrsRASRTVLLIAH-RLSTVERADQILVL-------KKGSVVEMGTHKQLMEDQ 704
|
|
| ABC_Carb_Monos_II |
cd03215 |
Second domain of the ATP-binding cassette component of monosaccharide transport system; This ... |
16-213 |
2.68e-17 |
|
Second domain of the ATP-binding cassette component of monosaccharide transport system; This family represents domain II of the carbohydrate uptake proteins that transport only monosaccharides (Monos). The Carb_Monos family is involved in the uptake of monosaccharides, such as pentoses (such as xylose, arabinose, and ribose) and hexoses (such as xylose, arabinose, and ribose), that cannot be broken down to simple sugars by hydrolysis. In members of Carb_Monos family the single hydrophobic gene product forms a homodimer, while the ABC protein represents a fusion of two nucleotide-binding domains. However, it is assumed that two copies of the ABC domains are present in the assembled transporter.
Pssm-ID: 213182 [Multi-domain] Cd Length: 182 Bit Score: 79.01 E-value: 2.68e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 16 GAPVIRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLSIGGK-IMNDVP--AAQRGVAMV---FQSYALFP 89
Cdd:cd03215 12 VKGAVRDVSFEVRAGEIVGIAGLVGNGQTELAEALFGLRPPASGEITLDGKpVTRRSPrdAIRAGIAYVpedRKREGLVL 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 90 HMTVFENMAFGLklaktpkeeidrkvreaarvlqleallerrpkALSGGQRQRVAIGRAIVRQPGVFLFDEPlsnldaTl 169
Cdd:cd03215 92 DLSVAENIALSS--------------------------------LLSGGNQQKVVLARWLARDPRVLILDEP------T- 132
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 928002514 170 RG---QTRIEIARLHKQFAKA--SVVYVTHDQIEAMTLADKIVLLHAGK 213
Cdd:cd03215 133 RGvdvGAKAEIYRLIRELADAgkAVLLISSELDELLGLCDRILVMYEGR 181
|
|
| ABCF_EF-3 |
cd03221 |
ATP-binding cassette domain of elongation factor 3, subfamily F; Elongation factor 3 (EF-3) is ... |
4-213 |
2.77e-17 |
|
ATP-binding cassette domain of elongation factor 3, subfamily F; Elongation factor 3 (EF-3) is a cytosolic protein required by fungal ribosomes for in vitro protein synthesis and for in vivo growth. EF-3 stimulates the binding of the EF-1: GTP: aa-tRNA ternary complex to the ribosomal A site by facilitated release of the deacylated tRNA from the E site. The reaction requires ATP hydrolysis. EF-3 contains two ATP nucleotide binding sequence (NBS) motifs. NBSI is sufficient for the intrinsic ATPase activity. NBSII is essential for the ribosome-stimulated functions.
Pssm-ID: 213188 [Multi-domain] Cd Length: 144 Bit Score: 77.87 E-value: 2.77e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 4 ISLRGVQKAYGDGaPVIRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLSIGGKImndvpaaqrgvamvfq 83
Cdd:cd03221 1 IELENLSKTYGGK-LLLKDISLTINPGDRIGLVGRNGAGKSTLLKLIAGELEPDEGIVTWGSTV---------------- 63
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 84 SYALFPHmtvfenmafglklaktpkeeidrkvreaarvlqleallerrpkaLSGGQRQRVAIGRAIVRQPGVFLFDEPLS 163
Cdd:cd03221 64 KIGYFEQ--------------------------------------------LSGGEKMRLALAKLLLENPNLLLLDEPTN 99
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 928002514 164 NLDAtlrgQTRIEIARLHKQFAKAsVVYVTHDQ--IEAmtLADKIVLLHAGK 213
Cdd:cd03221 100 HLDL----ESIEALEEALKEYPGT-VILVSHDRyfLDQ--VATKIIELEDGK 144
|
|
| btuD |
PRK09536 |
corrinoid ABC transporter ATPase; Reviewed |
1-227 |
4.10e-17 |
|
corrinoid ABC transporter ATPase; Reviewed
Pssm-ID: 236554 [Multi-domain] Cd Length: 402 Bit Score: 82.20 E-value: 4.10e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 1 MASISLRGVQKAYGDgAPVIRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLSIGGKIMN--DVPAAQRGV 78
Cdd:PRK09536 1 MPMIDVSDLSVEFGD-TTVLDGVDLSVREGSLVGLVGPNGAGKTTLLRAINGTLTPTAGTVLVAGDDVEalSARAASRRV 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 79 AMVFQSYAL--------------FPHMTVFENMAfglklaktpkEEIDRKVREAARVLQLEALLERRPKALSGGQRQRVA 144
Cdd:PRK09536 80 ASVPQDTSLsfefdvrqvvemgrTPHRSRFDTWT----------ETDRAAVERAMERTGVAQFADRPVTSLSGGERQRVL 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 145 IGRAIVRQPGVFLFDEPLSNLDATLRGQTrIEIARLHKQFAKAsVVYVTHDQIEAMTLADKIVLLHAgkdteryGSIAQI 224
Cdd:PRK09536 150 LARALAQATPVLLLDEPTASLDINHQVRT-LELVRRLVDDGKT-AVAAIHDLDLAARYCDELVLLAD-------GRVRAA 220
|
...
gi 928002514 225 GAP 227
Cdd:PRK09536 221 GPP 223
|
|
| livG |
PRK11300 |
leucine/isoleucine/valine transporter ATP-binding subunit; Provisional |
23-234 |
4.29e-17 |
|
leucine/isoleucine/valine transporter ATP-binding subunit; Provisional
Pssm-ID: 183080 [Multi-domain] Cd Length: 255 Bit Score: 80.03 E-value: 4.29e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 23 VDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLSIGGKIMNDVPA---AQRGVAMVFQSYALFPHMTVFENM-- 97
Cdd:PRK11300 24 VNLEVREQEIVSLIGPNGAGKTTVFNCLTGFYKPTGGTILLRGQHIEGLPGhqiARMGVVRTFQHVRLFREMTVIENLlv 103
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 98 --------AFGLKLAKTP------KEEIDRkvreAARVLQLEALLE---RRPKALSGGQRQRVAIGRAIVRQPGVFLFDE 160
Cdd:PRK11300 104 aqhqqlktGLFSGLLKTPafrraeSEALDR----AATWLERVGLLEhanRQAGNLAYGQQRRLEIARCMVTQPEILMLDE 179
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 928002514 161 PLsnldATLRGQTRIE----IARLHKQFaKASVVYVTHDQIEAMTLADKIVLLHAGKdterygSIAQiGAPLELYHRP 234
Cdd:PRK11300 180 PA----AGLNPKETKEldelIAELRNEH-NVTVLLIEHDMKLVMGISDRIYVVNQGT------PLAN-GTPEEIRNNP 245
|
|
| PRK11147 |
PRK11147 |
ABC transporter ATPase component; Reviewed |
1-213 |
6.24e-17 |
|
ABC transporter ATPase component; Reviewed
Pssm-ID: 236861 [Multi-domain] Cd Length: 635 Bit Score: 82.31 E-value: 6.24e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 1 MASISLRGVQKAYGDgAPVIRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLSIGGKIM-----NDVPAAQ 75
Cdd:PRK11147 1 MSLISIHGAWLSFSD-APLLDNAELHIEDNERVCLVGRNGAGKSTLMKILNGEVLLDDGRIIYEQDLIvarlqQDPPRNV 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 76 RGvamvfqsyalfphmTVFENMAFGLK---------------LAKTPKEEIDRKVREAARVL------QLE-------AL 127
Cdd:PRK11147 80 EG--------------TVYDFVAEGIEeqaeylkryhdishlVETDPSEKNLNELAKLQEQLdhhnlwQLEnrinevlAQ 145
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 128 LERRPKA----LSGGQRQRVAIGRAIVRQPGVFLFDEPLSNLDAtlrgqTRIE-IARLHKQFaKASVVYVTHDQ--IEAM 200
Cdd:PRK11147 146 LGLDPDAalssLSGGWLRKAALGRALVSNPDVLLLDEPTNHLDI-----ETIEwLEGFLKTF-QGSIIFISHDRsfIRNM 219
|
250
....*....|...
gi 928002514 201 tlADKIVLLHAGK 213
Cdd:PRK11147 220 --ATRIVDLDRGK 230
|
|
| PRK09700 |
PRK09700 |
D-allose ABC transporter ATP-binding protein AlsA; |
4-212 |
8.25e-17 |
|
D-allose ABC transporter ATP-binding protein AlsA;
Pssm-ID: 182036 [Multi-domain] Cd Length: 510 Bit Score: 81.75 E-value: 8.25e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 4 ISLRGVQKAYGdGAPVIRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLSIGGKIMNDVP---AAQRGVAM 80
Cdd:PRK09700 6 ISMAGIGKSFG-PVHALKSVNLTVYPGEIHALLGENGAGKSTLMKVLSGIHEPTKGTITINNINYNKLDhklAAQLGIGI 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 81 VFQSYALFPHMTVFENMAFGLKLAKT--PKEEID-RKVREAARVLQLEALLERRPKA----LSGGQRQRVAIGRAIVRQP 153
Cdd:PRK09700 85 IYQELSVIDELTVLENLYIGRHLTKKvcGVNIIDwREMRVRAAMMLLRVGLKVDLDEkvanLSISHKQMLEIAKTLMLDA 164
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 928002514 154 GVFLFDEPLSNLDATLRGQTRIEIARLHKQfaKASVVYVTHDQIEAMTLADKIVLLHAG 212
Cdd:PRK09700 165 KVIIMDEPTSSLTNKEVDYLFLIMNQLRKE--GTAIVYISHKLAEIRRICDRYTVMKDG 221
|
|
| PRK10790 |
PRK10790 |
SmdB family multidrug efflux ABC transporter permease/ATP-binding protein; |
3-217 |
8.46e-17 |
|
SmdB family multidrug efflux ABC transporter permease/ATP-binding protein;
Pssm-ID: 182733 [Multi-domain] Cd Length: 592 Bit Score: 82.07 E-value: 8.46e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 3 SISLRGVQKAYGDGAPVIRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLSIGGKIMNDVP--AAQRGVAM 80
Cdd:PRK10790 340 RIDIDNVSFAYRDDNLVLQNINLSVPSRGFVALVGHTGSGKSTLASLLMGYYPLTEGEIRLDGRPLSSLShsVLRQGVAM 419
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 81 VFQSYALFPHmTVFENMAFGLKLAktpkEEidrKVREAARVLQLEALLERRPKA-----------LSGGQRQRVAIGRAI 149
Cdd:PRK10790 420 VQQDPVVLAD-TFLANVTLGRDIS----EE---QVWQALETVQLAELARSLPDGlytplgeqgnnLSVGQKQLLALARVL 491
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 928002514 150 VRQPGVFLFDEPLSNLDATlrgqTRIEIARLHKQFAKASVVYVTHDQIEAMTLADKIVLLHAGKDTER 217
Cdd:PRK10790 492 VQTPQILILDEATANIDSG----TEQAIQQALAAVREHTTLVVIAHRLSTIVEADTILVLHRGQAVEQ 555
|
|
| YejF |
COG4172 |
ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites ... |
4-224 |
9.56e-17 |
|
ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites biosynthesis, transport and catabolism];
Pssm-ID: 443332 [Multi-domain] Cd Length: 533 Bit Score: 81.65 E-value: 9.56e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 4 ISLRGVQKAYGDGA---PVIRDVDLEIGENEFCVFLGPSGCGKS-TLLCmIAGLedLTDGDLSIGGKI------MNDVPA 73
Cdd:COG4172 7 LSVEDLSVAFGQGGgtvEAVKGVSFDIAAGETLALVGESGSGKSvTALS-ILRL--LPDPAAHPSGSIlfdgqdLLGLSE 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 74 AQ----RG--VAMVFQ--SYALFPHMTVFENMAFGLKLaktpKEEIDRkvREA-ARVLQL---------EALLERRPKAL 135
Cdd:COG4172 84 RElrriRGnrIAMIFQepMTSLNPLHTIGKQIAEVLRL----HRGLSG--AAArARALELlervgipdpERRLDAYPHQL 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 136 SGGQRQRVAIGRAIVRQPGVFLFDEPLSNLDATLRGQTRIEIARLHKQFaKASVVYVTHDqieaMTL----ADKIVLLHA 211
Cdd:COG4172 158 SGGQRQRVMIAMALANEPDLLIADEPTTALDVTVQAQILDLLKDLQREL-GMALLLITHD----LGVvrrfADRVAVMRQ 232
|
250
....*....|...
gi 928002514 212 GKDTERyGSIAQI 224
Cdd:COG4172 233 GEIVEQ-GPTAEL 244
|
|
| MglA |
COG1129 |
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; |
16-213 |
1.47e-16 |
|
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];
Pssm-ID: 440745 [Multi-domain] Cd Length: 497 Bit Score: 80.83 E-value: 1.47e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 16 GAPVIRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLSIGGKIM--NDVPAA-QRGVAMV---FQSYALFP 89
Cdd:COG1129 264 VGGVVRDVSFSVRAGEILGIAGLVGAGRTELARALFGADPADSGEIRLDGKPVriRSPRDAiRAGIAYVpedRKGEGLVL 343
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 90 HMTVFENMAFGL--KLAKTPKeeIDRKvREAARVLQL-EAL------LERRPKALSGGQRQRVAIGRAIVRQPGVFLFDE 160
Cdd:COG1129 344 DLSIRENITLASldRLSRGGL--LDRR-RERALAEEYiKRLriktpsPEQPVGNLSGGNQQKVVLAKWLATDPKVLILDE 420
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 928002514 161 PlsnldaTlRG---QTRIEIARLHKQFAKA--SVVYVTHDQIEAMTLADKIVLLHAGK 213
Cdd:COG1129 421 P------T-RGidvGAKAEIYRLIRELAAEgkAVIVISSELPELLGLSDRILVMREGR 471
|
|
| PRK10789 |
PRK10789 |
SmdA family multidrug ABC transporter permease/ATP-binding protein; |
18-232 |
1.65e-16 |
|
SmdA family multidrug ABC transporter permease/ATP-binding protein;
Pssm-ID: 182732 [Multi-domain] Cd Length: 569 Bit Score: 80.91 E-value: 1.65e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 18 PVIRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLSiggkiMNDVPAAQ------RG-VAMVFQSYALFPH 90
Cdd:PRK10789 329 PALENVNFTLKPGQMLGICGPTGSGKSTLLSLIQRHFDVSEGDIR-----FHDIPLTKlqldswRSrLAVVSQTPFLFSD 403
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 91 mTVFENMAFGLKLAKtpKEEIDrkvrEAARVLQLEALLERRPKA-----------LSGGQRQRVAIGRAIVRQPGVFLFD 159
Cdd:PRK10789 404 -TVANNIALGRPDAT--QQEIE----HVARLASVHDDILRLPQGydtevgergvmLSGGQKQRISIARALLLNAEILILD 476
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 928002514 160 EPLSNLDatlrGQTRIEIARLHKQFAKASVVYVTHDQIEAMTLADKIVLLHAGKDTERyGS----IAQIGAPLELYH 232
Cdd:PRK10789 477 DALSAVD----GRTEHQILHNLRQWGEGRTVIISAHRLSALTEASEILVMQHGHIAQR-GNhdqlAQQSGWYRDMYR 548
|
|
| TagH |
COG1134 |
ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate ... |
19-233 |
2.07e-16 |
|
ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate transport and metabolism];
Pssm-ID: 440749 [Multi-domain] Cd Length: 245 Bit Score: 77.81 E-value: 2.07e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 19 VIRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLSIGGKImndvpAAQRGVAMVFQsyalfPHMTVFENMA 98
Cdd:COG1134 41 ALKDVSFEVERGESVGIIGRNGAGKSTLLKLIAGILEPTSGRVEVNGRV-----SALLELGAGFH-----PELTGRENIY 110
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 99 FGLKLAKTPKEEIDRKVREAARVLQLEALLERRPKALSGGQRQRVAIGRAIVRQPGVFLFDEPLSNLDATLRGQTRIEIA 178
Cdd:COG1134 111 LNGRLLGLSRKEIDEKFDEIVEFAELGDFIDQPVKTYSSGMRARLAFAVATAVDPDILLVDEVLAVGDAAFQKKCLARIR 190
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 928002514 179 RLHKQfaKASVVYVTHD--QIEamTLADKIVLLHAGKDTErYGSIAQIgapLELYHR 233
Cdd:COG1134 191 ELRES--GRTVIFVSHSmgAVR--RLCDRAIWLEKGRLVM-DGDPEEV---IAAYEA 239
|
|
| met_CoM_red_A2 |
TIGR03269 |
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in ... |
4-275 |
2.42e-16 |
|
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in methanogenesis, methyl coenzyme M reductase, contains alpha, beta, and gamma chains. In older literature, the complex of alpha, beta, and gamma chains was termed component C, while this single chain protein was termed methyl coenzyme M reductase system component A2. [Energy metabolism, Methanogenesis]
Pssm-ID: 132313 [Multi-domain] Cd Length: 520 Bit Score: 80.23 E-value: 2.42e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 4 ISLRGVQKAYgDGAPVIRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTdgdlSIGGKIMN-----------DVP 72
Cdd:TIGR03269 1 IEVKNLTKKF-DGKEVLKNISFTIEEGEVLGILGRSGAGKSVLMHVLRGMDQYE----PTSGRIIYhvalcekcgyvERP 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 73 ------------------------------AAQRGVAMVFQ-SYALFPHMTVFENMAFGLKLAKTPKEEIDRKVREAARV 121
Cdd:TIGR03269 76 skvgepcpvcggtlepeevdfwnlsdklrrRIRKRIAIMLQrTFALYGDDTVLDNVLEALEEIGYEGKEAVGRAVDLIEM 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 122 LQLEALLERRPKALSGGQRQRVAIGRAIVRQPGVFLFDEPLSNLDAtlrgqtriEIARL-HKQFAKA------SVVYVTH 194
Cdd:TIGR03269 156 VQLSHRITHIARDLSGGEKQRVVLARQLAKEPFLFLADEPTGTLDP--------QTAKLvHNALEEAvkasgiSMVLTSH 227
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 195 --DQIEamTLADKIVLLHAgkdteryGSIAQIGAPLELYhrpkSRFVAGF----------IGSP--RMNFLPGRVASVDa 260
Cdd:TIGR03269 228 wpEVIE--DLSDKAIWLEN-------GEIKEEGTPDEVV----AVFMEGVsevekeceveVGEPiiKVRNVSKRYISVD- 293
|
330
....*....|....*
gi 928002514 261 QGVIVTLDTTLENVR 275
Cdd:TIGR03269 294 RGVVKAVDNVSLEVK 308
|
|
| PRK13539 |
PRK13539 |
cytochrome c biogenesis protein CcmA; Provisional |
16-167 |
6.61e-16 |
|
cytochrome c biogenesis protein CcmA; Provisional
Pssm-ID: 237421 [Multi-domain] Cd Length: 207 Bit Score: 75.68 E-value: 6.61e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 16 GAPVIRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLSI-GGKIMNDVPAAQrgVAMVFQSYALFPHMTVF 94
Cdd:PRK13539 14 GRVLFSGLSFTLAAGEALVLTGPNGSGKTTLLRLIAGLLPPAAGTIKLdGGDIDDPDVAEA--CHYLGHRNAMKPALTVA 91
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 928002514 95 ENMAFGLKLAKTPKEEIDrkvrEAARVLQLEALLERRPKALSGGQRQRVAIGRAIVRQPGVFLFDEPLSNLDA 167
Cdd:PRK13539 92 ENLEFWAAFLGGEELDIA----AALEAVGLAPLAHLPFGYLSAGQKRRVALARLLVSNRPIWILDEPTAALDA 160
|
|
| ABC2_perm_RbbA |
NF033858 |
ribosome-associated ATPase/putative transporter RbbA; |
22-213 |
7.72e-16 |
|
ribosome-associated ATPase/putative transporter RbbA;
Pssm-ID: 468210 [Multi-domain] Cd Length: 907 Bit Score: 79.40 E-value: 7.72e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 22 DVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLSIGGKIM--NDVpAAQRGVAMVFQSYALFPHMTVFENMAF 99
Cdd:NF033858 284 HVSFRIRRGEIFGFLGSNGCGKSTTMKMLTGLLPASEGEAWLFGQPVdaGDI-ATRRRVGYMSQAFSLYGELTVRQNLEL 362
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 100 GLKLAKTPKEEIDRKVREAARVLQLEALLERRPKALSGGQRQRVAIGRAIVRQPGVFLFDEPLSNLDATLRG---QTRIE 176
Cdd:NF033858 363 HARLFHLPAAEIAARVAEMLERFDLADVADALPDSLPLGIRQRLSLAVAVIHKPELLILDEPTSGVDPVARDmfwRLLIE 442
|
170 180 190
....*....|....*....|....*....|....*....
gi 928002514 177 IARlhkqfaKASV-VYV-THDQIEAMtLADKIVLLHAGK 213
Cdd:NF033858 443 LSR------EDGVtIFIsTHFMNEAE-RCDRISLMHAGR 474
|
|
| COG4586 |
COG4586 |
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ... |
20-213 |
8.46e-16 |
|
ABC-type uncharacterized transport system, ATPase component [General function prediction only];
Pssm-ID: 443643 [Multi-domain] Cd Length: 323 Bit Score: 77.43 E-value: 8.46e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 20 IRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLedL--TDGDLSIGGKimndVPAAQR-----GVAMVF-QSYALFPHM 91
Cdd:COG4586 38 VDDISFTIEPGEIVGFIGPNGAGKSTTIKMLTGI--LvpTSGEVRVLGY----VPFKRRkefarRIGVVFgQRSQLWWDL 111
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 92 TVFENmafgLKLAKT----PKEEIDRKVREAARVLQLEALLERRPKALSGGQRQRVAIGRAIVRQPGVFLFDEPLSNLDA 167
Cdd:COG4586 112 PAIDS----FRLLKAiyriPDAEYKKRLDELVELLDLGELLDTPVRQLSLGQRMRCELAAALLHRPKILFLDEPTIGLDV 187
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 928002514 168 TlrGQTRIE--IARLHKQFaKASVVYVTHD--QIEAmtLADKIVLLHAGK 213
Cdd:COG4586 188 V--SKEAIRefLKEYNRER-GTTILLTSHDmdDIEA--LCDRVIVIDHGR 232
|
|
| PRK09700 |
PRK09700 |
D-allose ABC transporter ATP-binding protein AlsA; |
20-224 |
1.41e-15 |
|
D-allose ABC transporter ATP-binding protein AlsA;
Pssm-ID: 182036 [Multi-domain] Cd Length: 510 Bit Score: 77.90 E-value: 1.41e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 20 IRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLSIGGKIM---NDVPAAQRGVAMVFQSY---ALFPHMTV 93
Cdd:PRK09700 279 VRDISFSVCRGEILGFAGLVGSGRTELMNCLFGVDKRAGGEIRLNGKDIsprSPLDAVKKGMAYITESRrdnGFFPNFSI 358
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 94 FENMAFG--LKLAK--------TPKEEidRKVREAAR-VLQLE-ALLERRPKALSGGQRQRVAIGRAIVRQPGVFLFDEP 161
Cdd:PRK09700 359 AQNMAISrsLKDGGykgamglfHEVDE--QRTAENQReLLALKcHSVNQNITELSGGNQQKVLISKWLCCCPEVIIFDEP 436
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 928002514 162 LSNLDATlrgqTRIEIARLHKQFAKA--SVVYVTHDQIEAMTLADKIVLLhagkdteRYGSIAQI 224
Cdd:PRK09700 437 TRGIDVG----AKAEIYKVMRQLADDgkVILMVSSELPEIITVCDRIAVF-------CEGRLTQI 490
|
|
| ABCC_CFTR1 |
cd03291 |
ATP-binding cassette domain of the cystic fibrosis transmembrane regulator, subfamily C; The ... |
16-212 |
1.43e-15 |
|
ATP-binding cassette domain of the cystic fibrosis transmembrane regulator, subfamily C; The CFTR subfamily domain 1. The cystic fibrosis transmembrane regulator (CFTR), the product of the gene mutated in patients with cystic fibrosis, has adapted the ABC transporter structural motif to form a tightly regulated anion channel at the apical surface of many epithelia. Use of the term assembly of a functional ion channel implies the coming together of subunits, or at least smaller not-yet functional components of the active whole. In fact, on the basis of current knowledge only the CFTR polypeptide itself is required to form an ATP- and protein kinase A-dependent low-conductance chloride channel of the type present in the apical membrane of many epithelial cells. CFTR displays the typical organization (IM-ABC)2 and carries a characteristic hydrophilic R-domain that separates IM1-ABC1 from IM2-ABC2.
Pssm-ID: 213258 [Multi-domain] Cd Length: 282 Bit Score: 76.05 E-value: 1.43e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 16 GAPVIRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLSIGGKImndvpaaqrgvAMVFQSYALFPHmTVFE 95
Cdd:cd03291 49 GAPVLKNINLKIEKGEMLAITGSTGSGKTSLLMLILGELEPSEGKIKHSGRI-----------SFSSQFSWIMPG-TIKE 116
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 96 NMAFGLKLAktpkeeiDRKVREAARVLQLEALLERRPK-----------ALSGGQRQRVAIGRAIVRQPGVFLFDEPLSN 164
Cdd:cd03291 117 NIIFGVSYD-------EYRYKSVVKACQLEEDITKFPEkdntvlgeggiTLSGGQRARISLARAVYKDADLYLLDSPFGY 189
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 928002514 165 LDatLRGQTRIEIARLHKQFAKASVVYVThDQIEAMTLADKIVLLHAG 212
Cdd:cd03291 190 LD--VFTEKEIFESCVCKLMANKTRILVT-SKMEHLKKADKILILHEG 234
|
|
| ccmA |
TIGR01189 |
heme ABC exporter, ATP-binding protein CcmA; This model describes the cyt c biogenesis protein ... |
15-194 |
1.71e-15 |
|
heme ABC exporter, ATP-binding protein CcmA; This model describes the cyt c biogenesis protein encoded by ccmA in bacteria. An exception is, an arabidopsis protein. Quite likely this is encoded by an organelle. Bacterial c-type cytocromes are located on the periplasmic side of the cytoplasmic membrane. Several gene products encoded in a locus designated as 'ccm' are implicated in the transport and assembly of the functional cytochrome C. This cluster includes genes: ccmA;B;C;D;E;F;G and H. The posttranslational pathway includes the transport of heme moiety, the secretion of the apoprotein and the covalent attachment of the heme with the apoprotein. The proteins ccmA and B represent an ABC transporter; ccmC and D participate in heme transfer to ccmE, which function as a periplasmic heme chaperone. The presence of ccmF, G and H is suggested to be obligatory for the final functional assembly of cytochrome c. [Protein fate, Protein and peptide secretion and trafficking, Transport and binding proteins, Other]
Pssm-ID: 273491 [Multi-domain] Cd Length: 198 Bit Score: 74.32 E-value: 1.71e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 15 DGAPVIRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLSIGGKIMNDV-PAAQRGVAMVFQSYALFPHMTV 93
Cdd:TIGR01189 11 GERMLFEGLSFTLNAGEALQVTGPNGIGKTTLLRILAGLLRPDSGEVRWNGTPLAEQrDEPHENILYLGHLPGLKPELSA 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 94 FENMAFGLKLAKTPkeeiDRKVREAARVLQLEALLERRPKALSGGQRQRVAIGRAIVRQPGVFLFDEPLSNLDATlrGQT 173
Cdd:TIGR01189 91 LENLHFWAAIHGGA----QRTIEDALAAVGLTGFEDLPAAQLSAGQQRRLALARLWLSRRPLWILDEPTTALDKA--GVA 164
|
170 180
....*....|....*....|..
gi 928002514 174 RI-EIARLHKQfAKASVVYVTH 194
Cdd:TIGR01189 165 LLaGLLRAHLA-RGGIVLLTTH 185
|
|
| MRP_assoc_pro |
TIGR00957 |
multi drug resistance-associated protein (MRP); This model describes multi drug ... |
15-233 |
1.91e-15 |
|
multi drug resistance-associated protein (MRP); This model describes multi drug resistance-associated protein (MRP) in eukaryotes. The multidrug resistance-associated protein is an integral membrane protein that causes multidrug resistance when overexpressed in mammalian cells. It belongs to ABC transporter superfamily. The protein topology and function was experimentally demonstrated by epitope tagging and immunofluorescence. Insertion of tags in the critical regions associated with drug efflux, abrogated its function. The C-terminal domain seem to highly conserved. [Transport and binding proteins, Other]
Pssm-ID: 188098 [Multi-domain] Cd Length: 1522 Bit Score: 78.45 E-value: 1.91e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 15 DGAPVIRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLSIGGKimndvpaaqrgVAMVFQSyALFPHMTVF 94
Cdd:TIGR00957 649 DLPPTLNGITFSIPEGALVAVVGQVGCGKSSLLSALLAEMDKVEGHVHMKGS-----------VAYVPQQ-AWIQNDSLR 716
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 95 ENMAFGLKLaktpKEEIDRKVREAARVL-QLEAL-------LERRPKALSGGQRQRVAIGRAIVRQPGVFLFDEPLSNLD 166
Cdd:TIGR00957 717 ENILFGKAL----NEKYYQQVLEACALLpDLEILpsgdrteIGEKGVNLSGGQKQRVSLARAVYSNADIYLFDDPLSAVD 792
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 928002514 167 ATLRGQTRIEIARLHKQFAKASVVYVTHDqIEAMTLADKIVLLHAGKdterygsIAQIGAPLELYHR 233
Cdd:TIGR00957 793 AHVGKHIFEHVIGPEGVLKNKTRILVTHG-ISYLPQVDVIIVMSGGK-------ISEMGSYQELLQR 851
|
|
| oppD |
PRK09473 |
oligopeptide transporter ATP-binding component; Provisional |
24-249 |
2.21e-15 |
|
oligopeptide transporter ATP-binding component; Provisional
Pssm-ID: 181888 [Multi-domain] Cd Length: 330 Bit Score: 76.30 E-value: 2.21e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 24 DLEIGENEFCVflGPSGCGKSTLLCMIAGL---EDLTDGDLSIGG--------KIMNDVPAAQrgVAMVFQS--YALFPH 90
Cdd:PRK09473 38 SLRAGETLGIV--GESGSGKSQTAFALMGLlaaNGRIGGSATFNGreilnlpeKELNKLRAEQ--ISMIFQDpmTSLNPY 113
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 91 MTVFENMAFGLKLAK--TPKEEIDRKVREAARVLQLEALLERR--PKALSGGQRQRVAIGRAIVRQPGVFLFDEPLSNLD 166
Cdd:PRK09473 114 MRVGEQLMEVLMLHKgmSKAEAFEESVRMLDAVKMPEARKRMKmyPHEFSGGMRQRVMIAMALLCRPKLLIADEPTTALD 193
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 167 ATLRGQTRIEIARLHKQFAKAsVVYVTHDQIEAMTLADKIVLLHAGKDTErYGSIAQIgaplelYHRPKSRFVAGFIGS- 245
Cdd:PRK09473 194 VTVQAQIMTLLNELKREFNTA-IIMITHDLGVVAGICDKVLVMYAGRTME-YGNARDV------FYQPSHPYSIGLLNAv 265
|
....
gi 928002514 246 PRMN 249
Cdd:PRK09473 266 PRLD 269
|
|
| ABCG_PDR_domain1 |
cd03233 |
First domain of the pleiotropic drug resistance-like subfamily G of ATP-binding cassette ... |
15-213 |
2.68e-15 |
|
First domain of the pleiotropic drug resistance-like subfamily G of ATP-binding cassette transporters; The pleiotropic drug resistance (PDR) is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. This PDR subfamily represents domain I of its (ABC-IM)2 organization. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds including sugars, ions, peptides, and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213200 [Multi-domain] Cd Length: 202 Bit Score: 73.84 E-value: 2.68e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 15 DGAPVIRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGledLTDGDLSIGGKIM-NDVPAA------QRGVAMVFQSYAL 87
Cdd:cd03233 18 SKIPILKDFSGVVKPGEMVLVLGRPGSGCSTLLKALAN---RTEGNVSVEGDIHyNGIPYKefaekyPGEIIYVSEEDVH 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 88 FPHMTVFENMAFGLKLAKtpkeeiDRKVReaarvlqleallerrpkALSGGQRQRVAIGRAIVRQPGVFLFDEPLSNLDA 167
Cdd:cd03233 95 FPTLTVRETLDFALRCKG------NEFVR-----------------GISGGERKRVSIAEALVSRASVLCWDNSTRGLDS 151
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 928002514 168 TlrgqTRIEIARLHKQFAKA--SVVYVTHDQI--EAMTLADKIVLLHAGK 213
Cdd:cd03233 152 S----TALEILKCIRTMADVlkTTTFVSLYQAsdEIYDLFDKVLVLYEGR 197
|
|
| PRK03695 |
PRK03695 |
vitamin B12-transporter ATPase; Provisional |
35-213 |
3.33e-15 |
|
vitamin B12-transporter ATPase; Provisional
Pssm-ID: 235150 [Multi-domain] Cd Length: 248 Bit Score: 74.58 E-value: 3.33e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 35 FLGPSGCGKSTLLCMIAGLEDlTDGDLSIGGKIMNDVPA---AQRGVAMVFQSYALFpHMTVFENMAFGLKlAKTPKEEI 111
Cdd:PRK03695 27 LVGPNGAGKSTLLARMAGLLP-GSGSIQFAGQPLEAWSAaelARHRAYLSQQQTPPF-AMPVFQYLTLHQP-DKTRTEAV 103
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 112 DRKVREAARVLQLEALLERRPKALSGGQRQRvaigraiVRQPGVFL--------------FDEPLSNLDATLRGQtrieI 177
Cdd:PRK03695 104 ASALNEVAEALGLDDKLGRSVNQLSGGEWQR-------VRLAAVVLqvwpdinpagqlllLDEPMNSLDVAQQAA----L 172
|
170 180 190
....*....|....*....|....*....|....*...
gi 928002514 178 ARLHKQFAKA--SVVYVTHDQIEAMTLADKIVLLHAGK 213
Cdd:PRK03695 173 DRLLSELCQQgiAVVMSSHDLNHTLRHADRVWLLKQGK 210
|
|
| PRK11174 |
PRK11174 |
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed |
15-224 |
3.58e-15 |
|
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed
Pssm-ID: 236870 [Multi-domain] Cd Length: 588 Bit Score: 76.81 E-value: 3.58e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 15 DGAPVIRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTdGDLSIGGKIMNDVPAAQ--RGVAMVFQSYALFpHMT 92
Cdd:PRK11174 361 DGKTLAGPLNFTLPAGQRIALVGPSGAGKTSLLNALLGFLPYQ-GSLKINGIELRELDPESwrKHLSWVGQNPQLP-HGT 438
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 93 VFENMAFGLKLAktPKEEIDRKVREAarvlQLEALLERRPK-----------ALSGGQRQRVAIGRAIVRQPGVFLFDEP 161
Cdd:PRK11174 439 LRDNVLLGNPDA--SDEQLQQALENA----WVSEFLPLLPQgldtpigdqaaGLSVGQAQRLALARALLQPCQLLLLDEP 512
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 928002514 162 LSNLDAtlRGQTRIEIArLHKQFAKASVVYVTHdQIEAMTLADKIVLLHAGKDTERyGSIAQI 224
Cdd:PRK11174 513 TASLDA--HSEQLVMQA-LNAASRRQTTLMVTH-QLEDLAQWDQIWVMQDGQIVQQ-GDYAEL 570
|
|
| CFTR_protein |
TIGR01271 |
cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis ... |
16-226 |
4.05e-15 |
|
cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis fibrosis transmembrane conductor regulator (CFTR) in eukaryotes. The principal role of this protein is chloride ion conductance. The protein is predicted to consist of 12 transmembrane domains. Mutations or lesions in the genetic loci have been linked to the aetiology of asthma, bronchiectasis, chronic obstructive pulmonary disease etc. Disease-causing mutations have been studied by 36Cl efflux assays in vitro cell cultures and electrophysiology, all of which point to the impairment of chloride channel stability and not the biosynthetic processing per se. [Transport and binding proteins, Anions]
Pssm-ID: 273530 [Multi-domain] Cd Length: 1490 Bit Score: 77.26 E-value: 4.05e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 16 GAPVIRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLSIGGKImndvpaaqrgvAMVFQSYALFPHmTVFE 95
Cdd:TIGR01271 438 VTPVLKNISFKLEKGQLLAVAGSTGSGKSSLLMMIMGELEPSEGKIKHSGRI-----------SFSPQTSWIMPG-TIKD 505
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 96 NMAFGLKLAktpkeeiDRKVREAARVLQLEALLERRPK-----------ALSGGQRQRVAIGRAIVRQPGVFLFDEPLSN 164
Cdd:TIGR01271 506 NIIFGLSYD-------EYRYTSVIKACQLEEDIALFPEkdktvlgeggiTLSGGQRARISLARAVYKDADLYLLDSPFTH 578
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 928002514 165 LDATlrgqTRIEIAR--LHKQFAKASVVYVThDQIEAMTLADKIVLLHAGKdTERYGSIAQIGA 226
Cdd:TIGR01271 579 LDVV----TEKEIFEscLCKLMSNKTRILVT-SKLEHLKKADKILLLHEGV-CYFYGTFSELQA 636
|
|
| ABCC_MRP_domain2 |
cd03244 |
ATP-binding cassette domain 2 of multidrug resistance-associated protein; The ABC subfamily C ... |
3-227 |
5.84e-15 |
|
ATP-binding cassette domain 2 of multidrug resistance-associated protein; The ABC subfamily C is also known as MRP (multidrug resistance-associated protein). Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resistance lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions, such as glutathione, glucuronate, and sulfate.
Pssm-ID: 213211 [Multi-domain] Cd Length: 221 Bit Score: 73.30 E-value: 5.84e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 3 SISLRGVQKAYGDG-APVIRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLSIGGKIMNDVPAAQ--RGVA 79
Cdd:cd03244 2 DIEFKNVSLRYRPNlPPVLKNISFSIKPGEKVGIVGRTGSGKSSLLLALFRLVELSSGSILIDGVDISKIGLHDlrSRIS 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 80 MVFQSYALFPHmTVFENMAFglkLAKTPKEEIDRKVREA-------ARVLQLEALLERRPKALSGGQRQRVAIGRAIVRQ 152
Cdd:cd03244 82 IIPQDPVLFSG-TIRSNLDP---FGEYSDEELWQALERVglkefveSLPGGLDTVVEEGGENLSVGQRQLLCLARALLRK 157
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 928002514 153 PGVFLFDEPLSNLDatlrGQTRIEIAR-LHKQFAKASVVYVTHdQIEAMTLADKIVLLHAGKdterygsIAQIGAP 227
Cdd:cd03244 158 SKILVLDEATASVD----PETDALIQKtIREAFKDCTVLTIAH-RLDTIIDSDRILVLDKGR-------VVEFDSP 221
|
|
| ABC_ABC_ChvD |
TIGR03719 |
ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of ... |
5-195 |
6.12e-15 |
|
ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of the ABC transporter ATP-binding cassette, but are found outside the common ABC transporter operon structure that features integral membrane permease proteins and substrate-binding proteins encoded next to the ATP-binding cassette (ABC domain) protein. The member protein ChvD from Agrobacterium tumefaciens was identified as both a candidate to interact with VirB8, based on yeast two-hybrid analysis, and as an apparent regulator of VirG. The general function of this protein family is unknown.
Pssm-ID: 274744 [Multi-domain] Cd Length: 552 Bit Score: 76.13 E-value: 6.12e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 5 SLRGVQKAYGDGAPVIRDVDL------EIGenefcvFLGPSGCGKSTLLCMIAGLedltdgDLSIGGKIMndvPAAQRGV 78
Cdd:TIGR03719 6 TMNRVSKVVPPKKEILKDISLsffpgaKIG------VLGLNGAGKSTLLRIMAGV------DKDFNGEAR---PQPGIKV 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 79 AMVFQSYALFPHMTVFENMAFGLKLAK--------------TPKEEIDRKVREAARvLQ----------LEALLERRPKA 134
Cdd:TIGR03719 71 GYLPQEPQLDPTKTVRENVEEGVAEIKdaldrfneisakyaEPDADFDKLAAEQAE-LQeiidaadawdLDSQLEIAMDA 149
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 928002514 135 L------------SGGQRQRVAIGRAIVRQPGVFLFDEPLSNLDATlrgqtriEIARL--HKQFAKASVVYVTHD 195
Cdd:TIGR03719 150 LrcppwdadvtklSGGERRRVALCRLLLSKPDMLLLDEPTNHLDAE-------SVAWLerHLQEYPGTVVAVTHD 217
|
|
| PTZ00243 |
PTZ00243 |
ABC transporter; Provisional |
19-213 |
6.95e-15 |
|
ABC transporter; Provisional
Pssm-ID: 240327 [Multi-domain] Cd Length: 1560 Bit Score: 76.74 E-value: 6.95e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 19 VIRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLsiggkimndvpAAQRGVAMVFQSyALFPHMTVFENMA 98
Cdd:PTZ00243 675 LLRDVSVSVPRGKLTVVLGATGSGKSTLLQSLLSQFEISEGRV-----------WAERSIAYVPQQ-AWIMNATVRGNIL 742
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 99 FGlklaktpKEEIDRKVREAARVLQLEALLERRPKA-----------LSGGQRQRVAIGRAIVRQPGVFLFDEPLSNLDA 167
Cdd:PTZ00243 743 FF-------DEEDAARLADAVRVSQLEADLAQLGGGleteigekgvnLSGGQKARVSLARAVYANRDVYLLDDPLSALDA 815
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 928002514 168 -------------TLRGQTRieiarlhkqfakasvVYVTHdQIEAMTLADKIVLLHAGK 213
Cdd:PTZ00243 816 hvgervveecflgALAGKTR---------------VLATH-QVHVVPRADYVVALGDGR 858
|
|
| PRK13657 |
PRK13657 |
glucan ABC transporter ATP-binding protein/ permease; |
4-167 |
7.30e-15 |
|
glucan ABC transporter ATP-binding protein/ permease;
Pssm-ID: 184214 [Multi-domain] Cd Length: 588 Bit Score: 76.15 E-value: 7.30e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 4 ISLRGVQKAYGDGAPVIRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLSIGGKIMNDVPAA--QRGVAMV 81
Cdd:PRK13657 335 VEFDDVSFSYDNSRQGVEDVSFEAKPGQTVAIVGPTGAGKSTLINLLQRVFDPQSGRILIDGTDIRTVTRAslRRNIAVV 414
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 82 FQSYALFpHMTVFENMAFGlKLAKTPKEeidrkVREAARVLQLEALLERRPK-----------ALSGGQRQRVAIGRAIV 150
Cdd:PRK13657 415 FQDAGLF-NRSIEDNIRVG-RPDATDEE-----MRAAAERAQAHDFIERKPDgydtvvgergrQLSGGERQRLAIARALL 487
|
170
....*....|....*..
gi 928002514 151 RQPGVFLFDEPLSNLDA 167
Cdd:PRK13657 488 KDPPILILDEATSALDV 504
|
|
| PhnL |
COG4778 |
Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnL [Inorganic ion ... |
18-207 |
8.86e-15 |
|
Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnL [Inorganic ion transport and metabolism];
Pssm-ID: 443809 [Multi-domain] Cd Length: 229 Bit Score: 72.85 E-value: 8.86e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 18 PVIRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDL---SIGGKImnDVPAA---------QRGVAMVFQSY 85
Cdd:COG4778 25 PVLDGVSFSVAAGECVALTGPSGAGKSTLLKCIYGNYLPDSGSIlvrHDGGWV--DLAQAspreilalrRRTIGYVSQFL 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 86 ALFPHMTVFENMAFGLKLAKTPKEEIDRKVREAARVLQL-EALLERRPKALSGGQRQRVAIGRAIVRQPGVFLFDEPLSN 164
Cdd:COG4778 103 RVIPRVSALDVVAEPLLERGVDREEARARARELLARLNLpERLWDLPPATFSGGEQQRVNIARGFIADPPLLLLDEPTAS 182
|
170 180 190 200
....*....|....*....|....*....|....*....|....
gi 928002514 165 LDATLRgQTRIEIARLHKQfAKASVVYVTHDqIEAM-TLADKIV 207
Cdd:COG4778 183 LDAANR-AVVVELIEEAKA-RGTAIIGIFHD-EEVReAVADRVV 223
|
|
| Rli1 |
COG1245 |
Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ... |
26-195 |
1.48e-14 |
|
Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ribosomal structure and biogenesis];
Pssm-ID: 440858 [Multi-domain] Cd Length: 592 Bit Score: 75.21 E-value: 1.48e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 26 EIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLSIGGKImndvpaaqrgvamvfqSYAlfP-------HMTVFENma 98
Cdd:COG1245 362 EIREGEVLGIVGPNGIGKTTFAKILAGVLKPDEGEVDEDLKI----------------SYK--PqyispdyDGTVEEF-- 421
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 99 fglkLAKTPKEEIDRKV--REAARVLQLEALLERRPKALSGGQRQRVAIGRAIVRQPGVFLFDEPLSNLDAtlrgQTRIE 176
Cdd:COG1245 422 ----LRSANTDDFGSSYykTEIIKPLGLEKLLDKNVKDLSGGELQRVAIAACLSRDADLYLLDEPSAHLDV----EQRLA 493
|
170 180
....*....|....*....|..
gi 928002514 177 IARLHKQFA---KASVVYVTHD 195
Cdd:COG1245 494 VAKAIRRFAenrGKTAMVVDHD 515
|
|
| 3a01204 |
TIGR00955 |
The Eye Pigment Precursor Transporter (EPP) Family protein; [Transport and binding proteins, ... |
36-230 |
1.55e-14 |
|
The Eye Pigment Precursor Transporter (EPP) Family protein; [Transport and binding proteins, Other]
Pssm-ID: 273361 [Multi-domain] Cd Length: 617 Bit Score: 75.08 E-value: 1.55e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 36 LGPSGCGKSTLLCMIAG--LEDLT-DGDLSIGGKIMnDVPAAQRGVAMVFQSYALFPHMTVFENMAFG--LKL-AKTPKE 109
Cdd:TIGR00955 57 MGSSGAGKTTLMNALAFrsPKGVKgSGSVLLNGMPI-DAKEMRAISAYVQQDDLFIPTLTVREHLMFQahLRMpRRVTKK 135
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 110 EIDRKVREaarVLQLEALL---------ERRPKALSGGQRQRVAIGRAIVRQPGVFLFDEPLSNLDATLRGQTrieIARL 180
Cdd:TIGR00955 136 EKRERVDE---VLQALGLRkcantrigvPGRVKGLSGGERKRLAFASELLTDPPLLFCDEPTSGLDSFMAYSV---VQVL 209
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 928002514 181 HKQFAKASVVYVTHDQ--IEAMTLADKIVLLHAGKdterygsIAQIGAPLEL 230
Cdd:TIGR00955 210 KGLAQKGKTIICTIHQpsSELFELFDKIILMAEGR-------VAYLGSPDQA 254
|
|
| PTZ00265 |
PTZ00265 |
multidrug resistance protein (mdr1); Provisional |
79-223 |
2.16e-14 |
|
multidrug resistance protein (mdr1); Provisional
Pssm-ID: 240339 [Multi-domain] Cd Length: 1466 Bit Score: 75.07 E-value: 2.16e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 79 AMVFQSYALFpHMTVFENMAFGlklaktpKEEIDRK-VREAARVLQLEALLERRP-----------KALSGGQRQRVAIG 146
Cdd:PTZ00265 1299 SIVSQEPMLF-NMSIYENIKFG-------KEDATREdVKRACKFAAIDEFIESLPnkydtnvgpygKSLSGGQKQRIAIA 1370
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 147 RAIVRQPGVFLFDEPLSNLDAT---LRGQTRIEIarlhKQFAKASVVYVTHdQIEAMTLADKIVLLHagkDTERYGSIAQ 223
Cdd:PTZ00265 1371 RALLREPKILLLDEATSSLDSNsekLIEKTIVDI----KDKADKTIITIAH-RIASIKRSDKIVVFN---NPDRTGSFVQ 1442
|
|
| ABC_FeS_Assembly |
cd03217 |
ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Biosynthesis of ... |
15-213 |
2.24e-14 |
|
ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Biosynthesis of iron-sulfur clusters (Fe-S) depends on multi-protein systems. The SUF system of E. coli and Erwinia chrysanthemi is important for Fe-S biogenesis under stressful conditions. The SUF system is made of six proteins: SufC is an atypical cytoplasmic ABC-ATPase, which forms a complex with SufB and SufD; SufA plays the role of a scaffold protein for assembly of iron-sulfur clusters and delivery to target proteins; SufS is a cysteine desulfurase which mobilizes the sulfur atom from cysteine and provides it to the cluster; SufE has no associated function yet.
Pssm-ID: 213184 [Multi-domain] Cd Length: 200 Bit Score: 71.02 E-value: 2.24e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 15 DGAPVIRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLED--LTDGDLSIGGKIMNDVPA---AQRGVAMVFQSYALFP 89
Cdd:cd03217 11 GGKEILKGVNLTIKKGEVHALMGPNGSGKSTLAKTIMGHPKyeVTEGEILFKGEDITDLPPeerARLGIFLAFQYPPEIP 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 90 hmtvfenmafGLKLAktpkeEIDRKVREaarvlqleallerrpkALSGGQRQRVAIGRAIVRQPGVFLFDEPLSNLDAT- 168
Cdd:cd03217 91 ----------GVKNA-----DFLRYVNE----------------GFSGGEKKRNEILQLLLLEPDLAILDEPDSGLDIDa 139
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 928002514 169 LRGQTRIeIARLHKQfaKASVVYVTH-----DQIEamtlADKIVLLHAGK 213
Cdd:cd03217 140 LRLVAEV-INKLREE--GKSVLIITHyqrllDYIK----PDRVHVLYDGR 182
|
|
| PRK11176 |
PRK11176 |
lipid A ABC transporter ATP-binding protein/permease MsbA; |
4-232 |
2.46e-14 |
|
lipid A ABC transporter ATP-binding protein/permease MsbA;
Pssm-ID: 183016 [Multi-domain] Cd Length: 582 Bit Score: 74.28 E-value: 2.46e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 4 ISLRGVQKAY-GDGAPVIRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLSIGGKIMND--VPAAQRGVAM 80
Cdd:PRK11176 342 IEFRNVTFTYpGKEVPALRNINFKIPAGKTVALVGRSGSGKSTIANLLTRFYDIDEGEILLDGHDLRDytLASLRNQVAL 421
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 81 VFQSYALFpHMTVFENMAFGLKlAKTPKEEIDRkvreAARVLQLEALLERRPKA-----------LSGGQRQRVAIGRAI 149
Cdd:PRK11176 422 VSQNVHLF-NDTIANNIAYART-EQYSREQIEE----AARMAYAMDFINKMDNGldtvigengvlLSGGQRQRIAIARAL 495
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 150 VRQPGVFLFDEPLSNLDATLRGQTRIEIARLHKQfaKASVVyVTH--DQIEAmtlADKIVLLHAGKDTERyGS----IAQ 223
Cdd:PRK11176 496 LRDSPILILDEATSALDTESERAIQAALDELQKN--RTSLV-IAHrlSTIEK---ADEILVVEDGEIVER-GThaelLAQ 568
|
....*....
gi 928002514 224 IGAPLELYH 232
Cdd:PRK11176 569 NGVYAQLHK 577
|
|
| PRK10253 |
PRK10253 |
iron-enterobactin ABC transporter ATP-binding protein; |
6-230 |
2.47e-14 |
|
iron-enterobactin ABC transporter ATP-binding protein;
Pssm-ID: 182336 [Multi-domain] Cd Length: 265 Bit Score: 72.33 E-value: 2.47e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 6 LRGVQKAYGDGA-PVIRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLSIGGKIMNDVPAAQ--RGVAMVF 82
Cdd:PRK10253 8 LRGEQLTLGYGKyTVAENLTVEIPDGHFTAIIGPNGCGKSTLLRTLSRLMTPAHGHVWLDGEHIQHYASKEvaRRIGLLA 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 83 QSYALFPHMTVFENMAFGlKLAKTP-----KEEIDRKVREAARVLQLEALLERRPKALSGGQRQRVAIGRAIVRQPGVFL 157
Cdd:PRK10253 88 QNATTPGDITVQELVARG-RYPHQPlftrwRKEDEEAVTKAMQATGITHLADQSVDTLSGGQRQRAWIAMVLAQETAIML 166
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 928002514 158 FDEPLSNLDATlrgqTRIEIARLHKQFAKA---SVVYVTHDQIEAMTLADKIVLLhagkdteRYGSIAQIGAPLEL 230
Cdd:PRK10253 167 LDEPTTWLDIS----HQIDLLELLSELNREkgyTLAAVLHDLNQACRYASHLIAL-------REGKIVAQGAPKEI 231
|
|
| PLN03130 |
PLN03130 |
ABC transporter C family member; Provisional |
18-216 |
8.24e-14 |
|
ABC transporter C family member; Provisional
Pssm-ID: 215595 [Multi-domain] Cd Length: 1622 Bit Score: 73.23 E-value: 8.24e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 18 PVIRDVDLEIGENEFCVFLGPSGCGKSTLL-CMIAGLEDLTDGDLSIGGKimndvpaaqrgVAMVFQSYALFpHMTVFEN 96
Cdd:PLN03130 631 PTLSNINLDVPVGSLVAIVGSTGEGKTSLIsAMLGELPPRSDASVVIRGT-----------VAYVPQVSWIF-NATVRDN 698
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 97 MAFGLKLAKTPKEE-IDrkVREAARVLQLEA---LLE--RRPKALSGGQRQRVAIGRAIVRQPGVFLFDEPLSNLDA--- 167
Cdd:PLN03130 699 ILFGSPFDPERYERaID--VTALQHDLDLLPggdLTEigERGVNISGGQKQRVSMARAVYSNSDVYIFDDPLSALDAhvg 776
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 928002514 168 ----------TLRGQTRieiarlhkqfakasvVYVThDQIEAMTLADKIVLLHAGKDTE 216
Cdd:PLN03130 777 rqvfdkcikdELRGKTR---------------VLVT-NQLHFLSQVDRIILVHEGMIKE 819
|
|
| MK0520 |
COG2401 |
ABC-type ATPase fused to a predicted acetyltransferase domain [General function prediction ... |
4-212 |
9.13e-14 |
|
ABC-type ATPase fused to a predicted acetyltransferase domain [General function prediction only];
Pssm-ID: 441957 [Multi-domain] Cd Length: 222 Bit Score: 69.99 E-value: 9.13e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 4 ISLRGVQKaygdgaPVIRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEdltdgdLSIGGKIMNDVPAAQRGvamvfq 83
Cdd:COG2401 36 VELRVVER------YVLRDLNLEIEPGEIVLIVGASGSGKSTLLRLLAGAL------KGTPVAGCVDVPDNQFG------ 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 84 syalfPHMTVFENMAfglklaktPKEEIDRKVREAARV-LQLEALLERRPKALSGGQRQRVAIGRAIVRQPGVFLFDEPL 162
Cdd:COG2401 98 -----REASLIDAIG--------RKGDFKDAVELLNAVgLSDAVLWLRRFKELSTGQKFRFRLALLLAERPKLLVIDEFC 164
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 928002514 163 SNLDATLRGQTRIEIARLHKQFAKASVVYVTHDQIEAMTLADKIVLLHAG 212
Cdd:COG2401 165 SHLDRQTAKRVARNLQKLARRAGITLVVATHHYDVIDDLQPDLLIFVGYG 214
|
|
| xylG |
TIGR02633 |
D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose ... |
4-213 |
1.48e-13 |
|
D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose isomerase and xylulokinase enzymes for xylose utilization. Members of this protein family are the ATP-binding cassette (ABC) subunit of the known or predicted high-affinity xylose ABC transporter for xylose import. These genes, which closely resemble other sugar transport ABC transporter genes, typically are encoded near xylose utilization enzymes and regulatory proteins. Note that this form of the transporter contains two copies of the ABC transporter domain (pfam00005). [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]
Pssm-ID: 131681 [Multi-domain] Cd Length: 500 Bit Score: 71.78 E-value: 1.48e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 4 ISLRGVQKAYGdGAPVIRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGL--EDLTDGDLSIGG---KIMNDVPAAQRGV 78
Cdd:TIGR02633 2 LEMKGIVKTFG-GVKALDGIDLEVRPGECVGLCGENGAGKSTLMKILSGVypHGTWDGEIYWSGsplKASNIRDTERAGI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 79 AMVFQSYALFPHMTVFENMAFG----LKLAKTPKEEIDRKVREAARVLQLEALLERRPKA-LSGGQRQRVAIGRAIVRQP 153
Cdd:TIGR02633 81 VIIHQELTLVPELSVAENIFLGneitLPGGRMAYNAMYLRAKNLLRELQLDADNVTRPVGdYGGGQQQLVEIAKALNKQA 160
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 154 GVFLFDEPLSNLDATlRGQTRIEIARLHKQFAKAsVVYVTHDQIEAMTLADKIVLLHAGK 213
Cdd:TIGR02633 161 RLLILDEPSSSLTEK-ETEILLDIIRDLKAHGVA-CVYISHKLNEVKAVCDTICVIRDGQ 218
|
|
| ABCC_SUR1_N |
cd03290 |
ATP-binding cassette domain of the sulfonylurea receptor, subfamily C; The SUR domain 1. The ... |
12-212 |
1.68e-13 |
|
ATP-binding cassette domain of the sulfonylurea receptor, subfamily C; The SUR domain 1. The sulfonylurea receptor SUR is an ATP transporter of the ABCC/MRP family with tandem ATPase binding domains. Unlike other ABC proteins, it has no intrinsic transport function, neither active nor passive, but associates with the potassium channel proteins Kir6.1 or Kir6.2 to form the ATP-sensitive potassium (K(ATP)) channel. Within the channel complex, SUR serves as a regulatory subunit that fine-tunes the gating of Kir6.x in response to alterations in cellular metabolism. It constitutes a major pharmaceutical target as it binds numerous drugs, K(ATP) channel openers and blockers, capable of up- or down-regulating channel activity.
Pssm-ID: 213257 [Multi-domain] Cd Length: 218 Bit Score: 69.28 E-value: 1.68e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 12 AYGDGAPVIRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLSIGGKIMN-----DVPAAQRG-VAMVFQSY 85
Cdd:cd03290 9 SWGSGLATLSNINIRIPTGQLTMIVGQVGCGKSSLLLAILGEMQTLEGKVHWSNKNESepsfeATRSRNRYsVAYAAQKP 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 86 ALFpHMTVFENMAFGlklakTPKEEIDRKVREAARVLQL---------EALLERRPKALSGGQRQRVAIGRAIVRQPGVF 156
Cdd:cd03290 89 WLL-NATVEENITFG-----SPFNKQRYKAVTDACSLQPdidllpfgdQTEIGERGINLSGGQRQRICVARALYQNTNIV 162
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 928002514 157 LFDEPLSNLDATLRGQTRIEIARLHKQFAKASVVYVTHdQIEAMTLADKIVLLHAG 212
Cdd:cd03290 163 FLDDPFSALDIHLSDHLMQEGILKFLQDDKRTLVLVTH-KLQYLPHADWIIAMKDG 217
|
|
| PRK13540 |
PRK13540 |
cytochrome c biogenesis protein CcmA; Provisional |
18-204 |
1.74e-13 |
|
cytochrome c biogenesis protein CcmA; Provisional
Pssm-ID: 184127 [Multi-domain] Cd Length: 200 Bit Score: 68.82 E-value: 1.74e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 18 PVIRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLSIGGK-IMNDVPAAQRGVAMVFQSYALFPHMTVFEN 96
Cdd:PRK13540 15 PLLQQISFHLPAGGLLHLKGSNGAGKTTLLKLIAGLLNPEKGEILFERQsIKKDLCTYQKQLCFVGHRSGINPYLTLREN 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 97 MAFGLKLAKTPKEeidrkVREAARVLQLEALLERRPKALSGGQRQRVAIGRAIVRQPGVFLFDEPLSNLD--ATLRGQTR 174
Cdd:PRK13540 95 CLYDIHFSPGAVG-----ITELCRLFSLEHLIDYPCGLLSSGQKRQVALLRLWMSKAKLWLLDEPLVALDelSLLTIITK 169
|
170 180 190
....*....|....*....|....*....|
gi 928002514 175 IEIARlhkqfAKASVVYVTHDQIEAMTLAD 204
Cdd:PRK13540 170 IQEHR-----AKGGAVLLTSHQDLPLNKAD 194
|
|
| PRK15134 |
PRK15134 |
microcin C ABC transporter ATP-binding protein YejF; Provisional |
37-233 |
2.14e-13 |
|
microcin C ABC transporter ATP-binding protein YejF; Provisional
Pssm-ID: 237917 [Multi-domain] Cd Length: 529 Bit Score: 71.27 E-value: 2.14e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 37 GPSGCGKST----LLCMIAgledlTDGDLSIGGKIMNDVPAAQ-----RGVAMVFQ--SYALFPHMTVFENMAFGLKL-- 103
Cdd:PRK15134 319 GESGSGKSTtglaLLRLIN-----SQGEIWFDGQPLHNLNRRQllpvrHRIQVVFQdpNSSLNPRLNVLQIIEEGLRVhq 393
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 104 AKTPKEEIDRKVREAARVLQLEALLERR-PKALSGGQRQRVAIGRAIVRQPGVFLFDEPLSNLDATLRGQTrIEIARLHK 182
Cdd:PRK15134 394 PTLSAAQREQQVIAVMEEVGLDPETRHRyPAEFSGGQRQRIAIARALILKPSLIILDEPTSSLDKTVQAQI-LALLKSLQ 472
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 928002514 183 QFAKASVVYVTHDQIEAMTLADKIVLLHAGKDTERyGSIAQI-GAPLELYHR 233
Cdd:PRK15134 473 QKHQLAYLFISHDLHVVRALCHQVIVLRQGEVVEQ-GDCERVfAAPQQEYTR 523
|
|
| ABCC_NFT1 |
cd03369 |
ATP-binding cassette domain 2 of NFT1, subfamily C; Domain 2 of NFT1 (New full-length MRP-type ... |
3-227 |
2.15e-13 |
|
ATP-binding cassette domain 2 of NFT1, subfamily C; Domain 2 of NFT1 (New full-length MRP-type transporter 1). NFT1 belongs to the MRP (multidrug resistance-associated protein) family of ABC transporters. Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resisting lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions such as glutathione, glucuronate, and sulfate.
Pssm-ID: 213269 [Multi-domain] Cd Length: 207 Bit Score: 68.59 E-value: 2.15e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 3 SISLRGVQKAYG-DGAPVIRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLSIGGKIMNDVP--AAQRGVA 79
Cdd:cd03369 6 EIEVENLSVRYApDLPPVLKNVSFKVKAGEKIGIVGRTGAGKSTLILALFRFLEAEEGKIEIDGIDISTIPleDLRSSLT 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 80 MVFQSYALFPHmTVFENM-AFGlklaktpkEEIDRKVREAARVLqlEALLErrpkaLSGGQRQRVAIGRAIVRQPGVFLF 158
Cdd:cd03369 86 IIPQDPTLFSG-TIRSNLdPFD--------EYSDEEIYGALRVS--EGGLN-----LSQGQRQLLCLARALLKRPRVLVL 149
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 159 DEPLSNLDAtlrgQTRIEIAR-LHKQFAKASVVYVTHdQIEAMTLADKIVLLHAGKdterygsIAQIGAP 227
Cdd:cd03369 150 DEATASIDY----ATDALIQKtIREEFTNSTILTIAH-RLRTIIDYDKILVMDAGE-------VKEYDHP 207
|
|
| PLN03211 |
PLN03211 |
ABC transporter G-25; Provisional |
31-168 |
2.33e-13 |
|
ABC transporter G-25; Provisional
Pssm-ID: 215634 [Multi-domain] Cd Length: 659 Bit Score: 71.45 E-value: 2.33e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 31 EFCVFLGPSGCGKSTLLCMIAGL---EDLTDGDLSIGGKIMNDVpaaQRGVAMVFQSYALFPHMTVFENMAFgLKLAKTP 107
Cdd:PLN03211 95 EILAVLGPSGSGKSTLLNALAGRiqgNNFTGTILANNRKPTKQI---LKRTGFVTQDDILYPHLTVRETLVF-CSLLRLP 170
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 108 KE-EIDRKVREAARVLQLEALLERRP--------KALSGGQRQRVAIGRAIVRQPGVFLFDEPLSNLDAT 168
Cdd:PLN03211 171 KSlTKQEKILVAESVISELGLTKCENtiignsfiRGISGGERKRVSIAHEMLINPSLLILDEPTSGLDAT 240
|
|
| PRK13409 |
PRK13409 |
ribosome biogenesis/translation initiation ATPase RLI; |
26-195 |
2.40e-13 |
|
ribosome biogenesis/translation initiation ATPase RLI;
Pssm-ID: 184037 [Multi-domain] Cd Length: 590 Bit Score: 71.38 E-value: 2.40e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 26 EIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLSIGGKImndvpaaqrgvamvfqSYA---LFP--HMTVFENmafg 100
Cdd:PRK13409 361 EIYEGEVIGIVGPNGIGKTTFAKLLAGVLKPDEGEVDPELKI----------------SYKpqyIKPdyDGTVEDL---- 420
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 101 lkLAKTP--------KEEIdrkvreaARVLQLEALLERRPKALSGGQRQRVAIGRAIVRQPGVFLFDEPLSNLDAtlrgQ 172
Cdd:PRK13409 421 --LRSITddlgssyyKSEI-------IKPLQLERLLDKNVKDLSGGELQRVAIAACLSRDADLYLLDEPSAHLDV----E 487
|
170 180
....*....|....*....|....*.
gi 928002514 173 TRIEIARLHKQFA---KASVVYVTHD 195
Cdd:PRK13409 488 QRLAVAKAIRRIAeerEATALVVDHD 513
|
|
| PRK10575 |
PRK10575 |
Fe3+-hydroxamate ABC transporter ATP-binding protein FhuC; |
33-230 |
4.17e-13 |
|
Fe3+-hydroxamate ABC transporter ATP-binding protein FhuC;
Pssm-ID: 182561 [Multi-domain] Cd Length: 265 Bit Score: 68.66 E-value: 4.17e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 33 CVFLGPSGCGKSTLLCMIAGLEDLTDGDLSIGGKIMN--DVPAAQRGVAMVFQSYALFPHMTVFENMAFGL-----KLAK 105
Cdd:PRK10575 40 TGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLEswSSKAFARKVAYLPQQLPAAEGMTVRELVAIGRypwhgALGR 119
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 106 TPKEEiDRKVREAARVLQLEALLERRPKALSGGQRQRVAIGRAIVRQPGVFLFDEPLSNLDATLRGQTRIEIARLHKQFA 185
Cdd:PRK10575 120 FGAAD-REKVEEAISLVGLKPLAHRLVDSLSGGERQRAWIAMLVAQDSRCLLLDEPTSALDIAHQVDVLALVHRLSQERG 198
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
gi 928002514 186 kASVVYVTHDQIEAMTLADKIVLLHAGKdterygSIAQiGAPLEL 230
Cdd:PRK10575 199 -LTVIAVLHDINMAARYCDYLVALRGGE------MIAQ-GTPAEL 235
|
|
| 3a01205 |
TIGR00956 |
Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other] |
36-223 |
4.87e-13 |
|
Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other]
Pssm-ID: 273362 [Multi-domain] Cd Length: 1394 Bit Score: 70.91 E-value: 4.87e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 36 LGPSGCGKSTLLCMIAglEDLTDGDLSIGGKIMNDVP---AAQRGVAMVFQSYALFPHMTVFENMAFGLKL---AKTPKE 109
Cdd:TIGR00956 795 MGASGAGKTTLLNVLA--ERVTTGVITGGDRLVNGRPldsSFQRSIGYVQQQDLHLPTSTVRESLRFSAYLrqpKSVSKS 872
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 110 EIDRKVREAARVLQLE----ALLERRPKALSGGQRQRVAIGRAIVRQPGVFLF-DEPLSNLDAtlrgQTRIEIARLHKQF 184
Cdd:TIGR00956 873 EKMEYVEEVIKLLEMEsyadAVVGVPGEGLNVEQRKRLTIGVELVAKPKLLLFlDEPTSGLDS----QTAWSICKLMRKL 948
|
170 180 190 200
....*....|....*....|....*....|....*....|...
gi 928002514 185 AKA--SVVYVTHdQIEAMTLA--DKIVLLHAGKDTERYGSIAQ 223
Cdd:TIGR00956 949 ADHgqAILCTIH-QPSAILFEefDRLLLLQKGGQTVYFGDLGE 990
|
|
| ABCD_peroxisomal_ALDP |
cd03223 |
ATP-binding cassette domain of peroxisomal transporter, subfamily D; Peroxisomal ATP-binding ... |
4-194 |
5.10e-13 |
|
ATP-binding cassette domain of peroxisomal transporter, subfamily D; Peroxisomal ATP-binding cassette transporter (Pat) is involved in the import of very long-chain fatty acids (VLCFA) into the peroxisome. The peroxisomal membrane forms a permeability barrier for a wide variety of metabolites required for and formed during fatty acid beta-oxidation. To communicate with the cytoplasm and mitochondria, peroxisomes need dedicated proteins to transport such hydrophilic molecules across their membranes. X-linked adrenoleukodystrophy (X-ALD) is caused by mutations in the ALD gene, which encodes ALDP (adrenoleukodystrophy protein ), a peroxisomal integral membrane protein that is a member of the ATP-binding cassette (ABC) transporter protein family. The disease is characterized by a striking and unpredictable variation in phenotypic expression. Phenotypes include the rapidly progressive childhood cerebral form (CCALD), the milder adult form, adrenomyeloneuropathy (AMN), and variants without neurologic involvement (i.e. asymptomatic).
Pssm-ID: 213190 [Multi-domain] Cd Length: 166 Bit Score: 66.41 E-value: 5.10e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 4 ISLRGVQKAYGDGAPVIRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLSIggkimndvpAAQRGVAMVFQ 83
Cdd:cd03223 1 IELENLSLATPDGRVLLKDLSFEIKPGDRLLITGPSGTGKSSLFRALAGLWPWGSGRIGM---------PEGEDLLFLPQ 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 84 -SYalfphmtvfenMAFG-LKlaktpkeeidrkvreaarvlqlEALLerRP--KALSGGQRQRVAIGRAIVRQPGVFLFD 159
Cdd:cd03223 72 rPY-----------LPLGtLR----------------------EQLI--YPwdDVLSGGEQQRLAFARLLLHKPKFVFLD 116
|
170 180 190
....*....|....*....|....*....|....*..
gi 928002514 160 EPLSNLDATLRgqtrieiARLHKQF--AKASVVYVTH 194
Cdd:cd03223 117 EATSALDEESE-------DRLYQLLkeLGITVISVGH 146
|
|
| ABC_CcmA_heme_exporter |
cd03231 |
Cytochrome c biogenesis ATP-binding export protein; CcmA, the ATP-binding component of the ... |
15-194 |
5.19e-13 |
|
Cytochrome c biogenesis ATP-binding export protein; CcmA, the ATP-binding component of the bacterial CcmAB transporter. The CCM family is involved in bacterial cytochrome c biogenesis. Cytochrome c maturation in E. coli requires the ccm operon, which encodes eight membrane proteins (CcmABCDEFGH). CcmE is a periplasmic heme chaperon that binds heme covalently and transfers it onto apocytochrome c in the presence of CcmF, CcmG, and CcmH. The CcmAB proteins represent an ABC transporter and the CcmCD proteins participate in heme transfer to CcmE.
Pssm-ID: 213198 [Multi-domain] Cd Length: 201 Bit Score: 67.13 E-value: 5.19e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 15 DGAPVIRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLSI-GGKIMNDVPAAQRGVAMVFQSYALFPHMTV 93
Cdd:cd03231 11 DGRALFSGLSFTLAAGEALQVTGPNGSGKTTLLRILAGLSPPLAGRVLLnGGPLDFQRDSIARGLLYLGHAPGIKTTLSV 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 94 FENMAFGLKLAKtpkeeiDRKVREAARVLQLEALLERRPKALSGGQRQRVAIGRAIVRQPGVFLFDEPLSNLDATlrgqt 173
Cdd:cd03231 91 LENLRFWHADHS------DEQVEEALARVGLNGFEDRPVAQLSAGQQRRVALARLLLSGRPLWILDEPTTALDKA----- 159
|
170 180
....*....|....*....|....*.
gi 928002514 174 riEIARLHKQFAK-----ASVVYVTH 194
Cdd:cd03231 160 --GVARFAEAMAGhcargGMVVLTTH 183
|
|
| 3a01205 |
TIGR00956 |
Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other] |
19-213 |
6.83e-13 |
|
Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other]
Pssm-ID: 273362 [Multi-domain] Cd Length: 1394 Bit Score: 70.52 E-value: 6.83e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 19 VIRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLED----LTDGDLSIGGKIMNDVPAAQRG-VAMVFQSYALFPHMTV 93
Cdd:TIGR00956 76 ILKPMDGLIKPGELTVVLGRPGSGCSTLLKTIASNTDgfhiGVEGVITYDGITPEEIKKHYRGdVVYNAETDVHFPHLTV 155
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 94 FENMAFGLKLaKTPK---EEIDRKVR---EAARVLQLEALLERRP--------KALSGGQRQRVAIGRAIVRQPGVFLFD 159
Cdd:TIGR00956 156 GETLDFAARC-KTPQnrpDGVSREEYakhIADVYMATYGLSHTRNtkvgndfvRGVSGGERKRVSIAEASLGGAKIQCWD 234
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 928002514 160 EPLSNLDATlrgqTRIEIARLHKQFAK--ASVVYVTHDQI--EAMTLADKIVLLHAGK 213
Cdd:TIGR00956 235 NATRGLDSA----TALEFIRALKTSANilDTTPLVAIYQCsqDAYELFDKVIVLYEGY 288
|
|
| Rli1 |
COG1245 |
Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ... |
114-210 |
1.45e-12 |
|
Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ribosomal structure and biogenesis];
Pssm-ID: 440858 [Multi-domain] Cd Length: 592 Bit Score: 69.04 E-value: 1.45e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 114 KVREAARVLQLEALLERRPKALSGGQRQRVAIGRAIVRQPGVFLFDEPLSNLDAtlrGQtRIEIARLHKQFAKA--SVVY 191
Cdd:COG1245 192 KLDELAEKLGLENILDRDISELSGGELQRVAIAAALLRDADFYFFDEPSSYLDI---YQ-RLNVARLIRELAEEgkYVLV 267
|
90
....*....|....*....
gi 928002514 192 VTHDQIEAMTLADKIVLLH 210
Cdd:COG1245 268 VEHDLAILDYLADYVHILY 286
|
|
| PRK11819 |
PRK11819 |
putative ABC transporter ATP-binding protein; Reviewed |
5-195 |
1.83e-12 |
|
putative ABC transporter ATP-binding protein; Reviewed
Pssm-ID: 236992 [Multi-domain] Cd Length: 556 Bit Score: 68.61 E-value: 1.83e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 5 SLRGVQKAYGDGAPVIRDVDL------EIGenefcvFLGPSGCGKSTLLCMIAGLEDLTDGDLsiggkimndVPAAQRGV 78
Cdd:PRK11819 8 TMNRVSKVVPPKKQILKDISLsffpgaKIG------VLGLNGAGKSTLLRIMAGVDKEFEGEA---------RPAPGIKV 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 79 AMVFQSYALFPHMTVFEN--MAFGLKLAK------------TPKEEIDRKVREAARvLQ----------LEALLE----- 129
Cdd:PRK11819 73 GYLPQEPQLDPEKTVRENveEGVAEVKAAldrfneiyaayaEPDADFDALAAEQGE-LQeiidaadawdLDSQLEiamda 151
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 928002514 130 -RRP------KALSGGQRQRVAIGRAIVRQPGVFLFDEPLSNLDAtlrgqtriE-IARL--HKQFAKASVVYVTHD 195
Cdd:PRK11819 152 lRCPpwdakvTKLSGGERRRVALCRLLLEKPDMLLLDEPTNHLDA--------EsVAWLeqFLHDYPGTVVAVTHD 219
|
|
| dppD |
PRK11022 |
dipeptide transporter ATP-binding subunit; Provisional |
1-255 |
2.72e-12 |
|
dipeptide transporter ATP-binding subunit; Provisional
Pssm-ID: 182906 [Multi-domain] Cd Length: 326 Bit Score: 67.07 E-value: 2.72e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 1 MASISLRGVQKAYGDGAPVIRDVD---LEIGENEFCVFLGPSGCGKSTLLCMIAGLED----LTDGDLSIGGKIMNDVPA 73
Cdd:PRK11022 1 MALLNVDKLSVHFGDESAPFRAVDrisYSVKQGEVVGIVGESGSGKSVSSLAIMGLIDypgrVMAEKLEFNGQDLQRISE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 74 AQR------GVAMVFQS--YALFPHMTVFENMAFGLKLaktpKEEIDRKVREAaRVLQL---------EALLERRPKALS 136
Cdd:PRK11022 81 KERrnlvgaEVAMIFQDpmTSLNPCYTVGFQIMEAIKV----HQGGNKKTRRQ-RAIDLlnqvgipdpASRLDVYPHQLS 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 137 GGQRQRVAIGRAIVRQPGVFLFDEPLSNLDATLRGQTrIEIARLHKQFAKASVVYVTHDQIEAMTLADKIVLLHAGKdte 216
Cdd:PRK11022 156 GGMSQRVMIAMAIACRPKLLIADEPTTALDVTIQAQI-IELLLELQQKENMALVLITHDLALVAEAAHKIIVMYAGQ--- 231
|
250 260 270 280
....*....|....*....|....*....|....*....|....*..
gi 928002514 217 rygsIAQIGAPLELYHRPKSRFVAGFI--------GSPRMNFLPGRV 255
Cdd:PRK11022 232 ----VVETGKAHDIFRAPRHPYTQALLralpefaqDKARLASLPGVV 274
|
|
| PLN03232 |
PLN03232 |
ABC transporter C family member; Provisional |
18-233 |
3.15e-12 |
|
ABC transporter C family member; Provisional
Pssm-ID: 215640 [Multi-domain] Cd Length: 1495 Bit Score: 68.46 E-value: 3.15e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 18 PVIRDVDLEIGENEFCVFLGPSGCGKSTLL-CMIAGLEDLTDGDLSIGGKimndvpaaqrgVAMVFQSYALFpHMTVFEN 96
Cdd:PLN03232 631 PTLSDINLEIPVGSLVAIVGGTGEGKTSLIsAMLGELSHAETSSVVIRGS-----------VAYVPQVSWIF-NATVREN 698
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 97 MAFGlklAKTPKEEIDRKVREAARVLQLEALLER-------RPKALSGGQRQRVAIGRAIVRQPGVFLFDEPLSNLDA-- 167
Cdd:PLN03232 699 ILFG---SDFESERYWRAIDVTALQHDLDLLPGRdlteigeRGVNISGGQKQRVSMARAVYSNSDIYIFDDPLSALDAhv 775
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 928002514 168 -----------TLRGQTRieiarlhkqfakasvVYVThDQIEAMTLADKIVLLHAGKDTERyGSIAQIGAPLELYHR 233
Cdd:PLN03232 776 ahqvfdscmkdELKGKTR---------------VLVT-NQLHFLPLMDRIILVSEGMIKEE-GTFAELSKSGSLFKK 835
|
|
| rim_protein |
TIGR01257 |
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim ... |
4-252 |
4.42e-12 |
|
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim protein) in eukaryotes. It is the member of ABC transporter superfamily. Rim protein is a membrane glycoprotein which is localized in the photoreceptor outer segment discs. Mutation/s in its genetic loci is implicated in the recessive Stargardt's disease. [Transport and binding proteins, Other]
Pssm-ID: 130324 [Multi-domain] Cd Length: 2272 Bit Score: 68.12 E-value: 4.42e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 4 ISLRGVQKAY-GDGAPVIRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLSIGGK-IMNDVPAAQRGVAMV 81
Cdd:TIGR01257 1938 LRLNELTKVYsGTSSPAVDRLCVGVRPGECFGLLGVNGAGKTTTFKMLTGDTTVTSGDATVAGKsILTNISDVHQNMGYC 2017
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 82 FQSYALFPHMTVFENMAFGLKLAKTPKEEIDRKVREAARVLQLEALLERRPKALSGGQRQRVAIGRAIVRQPGVFLFDEP 161
Cdd:TIGR01257 2018 PQFDAIDDLLTGREHLYLYARLRGVPAEEIEKVANWSIQSLGLSLYADRLAGTYSGGNKRKLSTAIALIGCPPLVLLDEP 2097
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 162 LSNLDATLRG---QTRIEIARLHKqfakaSVVYVTHDQIEAMTLADKIVLLHAGKdTERYGSIAQIgaplelyhrpKSRF 238
Cdd:TIGR01257 2098 TTGMDPQARRmlwNTIVSIIREGR-----AVVLTSHSMEECEALCTRLAIMVKGA-FQCLGTIQHL----------KSKF 2161
|
250
....*....|....*....
gi 928002514 239 VAGF-----IGSPRMNFLP 252
Cdd:TIGR01257 2162 GDGYivtmkIKSPKDDLLP 2180
|
|
| PRK10261 |
PRK10261 |
glutathione transporter ATP-binding protein; Provisional |
20-235 |
5.25e-12 |
|
glutathione transporter ATP-binding protein; Provisional
Pssm-ID: 182342 [Multi-domain] Cd Length: 623 Bit Score: 67.19 E-value: 5.25e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 20 IRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLSIGGKIMNDVPAAQ-----RGVAMVFQS-YA-LFPHMT 92
Cdd:PRK10261 340 VEKVSFDLWPGETLSLVGESGSGKSTTGRALLRLVESQGGEIIFNGQRIDTLSPGKlqalrRDIQFIFQDpYAsLDPRQT 419
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 93 VFENMAFGLKLAKT-PKEEIDRKVREA-ARVLQLEALLERRPKALSGGQRQRVAIGRAIVRQPGVFLFDEPLSNLDATLR 170
Cdd:PRK10261 420 VGDSIMEPLRVHGLlPGKAAAARVAWLlERVGLLPEHAWRYPHEFSGGQRQRICIARALALNPKVIIADEAVSALDVSIR 499
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 928002514 171 GQTRIEIARLHKQFAKAsVVYVTHDQIEAMTLADKIVLLHAGKdterygsIAQIGAPLELYHRPK 235
Cdd:PRK10261 500 GQIINLLLDLQRDFGIA-YLFISHDMAVVERISHRVAVMYLGQ-------IVEIGPRRAVFENPQ 556
|
|
| ABC_ABC_ChvD |
TIGR03719 |
ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of ... |
4-195 |
5.43e-12 |
|
ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of the ABC transporter ATP-binding cassette, but are found outside the common ABC transporter operon structure that features integral membrane permease proteins and substrate-binding proteins encoded next to the ATP-binding cassette (ABC domain) protein. The member protein ChvD from Agrobacterium tumefaciens was identified as both a candidate to interact with VirB8, based on yeast two-hybrid analysis, and as an apparent regulator of VirG. The general function of this protein family is unknown.
Pssm-ID: 274744 [Multi-domain] Cd Length: 552 Bit Score: 66.88 E-value: 5.43e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 4 ISLRGVQKAYGDgAPVIRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLSIGGKIMndvpaaqrgVAMVFQ 83
Cdd:TIGR03719 323 IEAENLTKAFGD-KLLIDDLSFKLPPGGIVGVIGPNGAGKSTLFRMITGQEQPDSGTIEIGETVK---------LAYVDQ 392
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 84 SY-ALFPHMTVFENMAFGLKLAKTPKEEIDRKvreaARVLQLE---ALLERRPKALSGGQRQRVAIGRaIVRQPG-VFLF 158
Cdd:TIGR03719 393 SRdALDPNKTVWEEISGGLDIIKLGKREIPSR----AYVGRFNfkgSDQQKKVGQLSGGERNRVHLAK-TLKSGGnVLLL 467
|
170 180 190
....*....|....*....|....*....|....*...
gi 928002514 159 DEPLSNLDA-TLRGqtrIEIARLhkQFAKASVVyVTHD 195
Cdd:TIGR03719 468 DEPTNDLDVeTLRA---LEEALL--NFAGCAVV-ISHD 499
|
|
| NupO |
COG3845 |
ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and ... |
15-213 |
5.52e-12 |
|
ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and metabolism];
Pssm-ID: 443055 [Multi-domain] Cd Length: 504 Bit Score: 66.97 E-value: 5.52e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 15 DGAPVIRDVDLEIGENE-FCVfLGPSGCGKSTLLCMIAGLEDLTDGDLSIGGKIMNDVPAAQR---GVAMV---FQSYAL 87
Cdd:COG3845 269 RGVPALKDVSLEVRAGEiLGI-AGVAGNGQSELAEALAGLRPPASGSIRLDGEDITGLSPRERrrlGVAYIpedRLGRGL 347
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 88 FPHMTVFENMAFGL----KLAKTPKeeIDRK-VREAArvlqlEALLER---RP-------KALSGGQRQRVAIGRAIVRQ 152
Cdd:COG3845 348 VPDMSVAENLILGRyrrpPFSRGGF--LDRKaIRAFA-----EELIEEfdvRTpgpdtpaRSLSGGNQQKVILARELSRD 420
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 928002514 153 PGVFLFDEPLSNLD--AtlrgqtrieIARLHKQFAK-----ASVVYVTHDQIEAMTLADKIVLLHAGK 213
Cdd:COG3845 421 PKLLIAAQPTRGLDvgA---------IEFIHQRLLElrdagAAVLLISEDLDEILALSDRIAVMYEGR 479
|
|
| PRK13409 |
PRK13409 |
ribosome biogenesis/translation initiation ATPase RLI; |
114-209 |
6.85e-12 |
|
ribosome biogenesis/translation initiation ATPase RLI;
Pssm-ID: 184037 [Multi-domain] Cd Length: 590 Bit Score: 66.76 E-value: 6.85e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 114 KVREAARVLQLEALLERRPKALSGGQRQRVAIGRAIVRQPGVFLFDEPLSNLDAtlrGQtRIEIARLHKQFAK-ASVVYV 192
Cdd:PRK13409 192 KLDEVVERLGLENILDRDISELSGGELQRVAIAAALLRDADFYFFDEPTSYLDI---RQ-RLNVARLIRELAEgKYVLVV 267
|
90
....*....|....*..
gi 928002514 193 THDQIEAMTLADKIVLL 209
Cdd:PRK13409 268 EHDLAVLDYLADNVHIA 284
|
|
| PRK15134 |
PRK15134 |
microcin C ABC transporter ATP-binding protein YejF; Provisional |
18-233 |
6.94e-12 |
|
microcin C ABC transporter ATP-binding protein YejF; Provisional
Pssm-ID: 237917 [Multi-domain] Cd Length: 529 Bit Score: 66.65 E-value: 6.94e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 18 PVIRDVDLEIGENEFCVFLGPSGCGKS-TLLCMIAGLED----LTDGDLSIGGKIMNDVPAAQ-RGV-----AMVFQS-- 84
Cdd:PRK15134 23 TVVNDVSLQIEAGETLALVGESGSGKSvTALSILRLLPSppvvYPSGDIRFHGESLLHASEQTlRGVrgnkiAMIFQEpm 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 85 YALFPHMTVFENMAFGLKLAKTPKeeidrkvREAARVLQLEAL-----------LERRPKALSGGQRQRVAIGRAIVRQP 153
Cdd:PRK15134 103 VSLNPLHTLEKQLYEVLSLHRGMR-------REAARGEILNCLdrvgirqaakrLTDYPHQLSGGERQRVMIAMALLTRP 175
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 154 GVFLFDEPLSNLDATLRGQTrIEIARLHKQFAKASVVYVTHDQIEAMTLADKIVLLHAGKDTERYGSIAQIGAPLELYHR 233
Cdd:PRK15134 176 ELLIADEPTTALDVSVQAQI-LQLLRELQQELNMGLLFITHNLSIVRKLADRVAVMQNGRCVEQNRAATLFSAPTHPYTQ 254
|
|
| ABC_RNaseL_inhibitor_domain1 |
cd03236 |
The ATP-binding cassette domain 1 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI) ... |
28-210 |
7.41e-12 |
|
The ATP-binding cassette domain 1 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI), is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI s are not transport proteins and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLIs have an N-terminal Fe-S domain and two nucleotide binding domains which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.
Pssm-ID: 213203 [Multi-domain] Cd Length: 255 Bit Score: 65.08 E-value: 7.41e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 28 GENEFCVF-------------LGPSGCGKSTLLCMIAG--------LEDLTDGDlsiggkimnDVPAAQRGVAMvfQSYa 86
Cdd:cd03236 11 GPNSFKLHrlpvpregqvlglVGPNGIGKSTALKILAGklkpnlgkFDDPPDWD---------EILDEFRGSEL--QNY- 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 87 lfphmtvFENMAFG-LKLAKTPK--EEIDRKVR-----------------EAARVLQLEALLERRPKALSGGQRQRVAIG 146
Cdd:cd03236 79 -------FTKLLEGdVKVIVKPQyvDLIPKAVKgkvgellkkkdergkldELVDQLELRHVLDRNIDQLSGGELQRVAIA 151
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 928002514 147 RAIVRQPGVFLFDEPLSNLDAtlrGQtRIEIARLHKQFAK--ASVVYVTHDQIEAMTLADKIVLLH 210
Cdd:cd03236 152 AALARDADFYFFDEPSSYLDI---KQ-RLNAARLIRELAEddNYVLVVEHDLAVLDYLSDYIHCLY 213
|
|
| ABCG_PDR_domain2 |
cd03232 |
Second domain of the pleiotropic drug resistance-like (PDR) subfamily G of ATP-binding ... |
22-219 |
7.83e-12 |
|
Second domain of the pleiotropic drug resistance-like (PDR) subfamily G of ATP-binding cassette transporters; The pleiotropic drug resistance (PDR) is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. This PDR subfamily represents domain I of its (ABC-IM)2 organization. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds including sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213199 [Multi-domain] Cd Length: 192 Bit Score: 63.80 E-value: 7.83e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 22 DVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLED--LTDGDLSIGGKIMNdvPAAQRGVAMVFQSYALFPHMTVfenmaf 99
Cdd:cd03232 25 NISGYVKPGTLTALMGESGAGKTTLLDVLAGRKTagVITGEILINGRPLD--KNFQRSTGYVEQQDVHSPNLTV------ 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 100 glklaktpkeeidrkvREAarvLQLEALLerrpKALSGGQRQRVAIGRAIVRQPGVFLFDEPLSNLDAtlrgQTRIEIAR 179
Cdd:cd03232 97 ----------------REA---LRFSALL----RGLSVEQRKRLTIGVELAAKPSILFLDEPTSGLDS----QAAYNIVR 149
|
170 180 190 200
....*....|....*....|....*....|....*....|....
gi 928002514 180 LHKQFAKA--SVVYVTHdQIEAMTLA--DKIVLLHAGKDTERYG 219
Cdd:cd03232 150 FLKKLADSgqAILCTIH-QPSASIFEkfDRLLLLKRGGKTVYFG 192
|
|
| PRK13549 |
PRK13549 |
xylose transporter ATP-binding subunit; Provisional |
6-213 |
8.57e-12 |
|
xylose transporter ATP-binding subunit; Provisional
Pssm-ID: 184134 [Multi-domain] Cd Length: 506 Bit Score: 66.49 E-value: 8.57e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 6 LRGVQKAYGdGAPVIRDVDLEIGENEfCVFL-GPSGCGKSTLLCMIAGL--EDLTDGDLSIGGKimnDVPAA------QR 76
Cdd:PRK13549 8 MKNITKTFG-GVKALDNVSLKVRAGE-IVSLcGENGAGKSTLMKVLSGVypHGTYEGEIIFEGE---ELQASnirdteRA 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 77 GVAMVFQSYALFPHMTVFENMAFGLKLAKTPKEEIDRKVREAARVL---QLEALLERRPKALSGGQRQRVAIGRAIVRQP 153
Cdd:PRK13549 83 GIAIIHQELALVKELSVLENIFLGNEITPGGIMDYDAMYLRAQKLLaqlKLDINPATPVGNLGLGQQQLVEIAKALNKQA 162
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 928002514 154 GVFLFDEPLSNLDAtlrGQTRI--EIARLHKQFAKAsVVYVTHDQIEAMTLADKIVLLHAGK 213
Cdd:PRK13549 163 RLLILDEPTASLTE---SETAVllDIIRDLKAHGIA-CIYISHKLNEVKAISDTICVIRDGR 220
|
|
| PRK15056 |
PRK15056 |
manganese/iron ABC transporter ATP-binding protein; |
2-166 |
1.33e-11 |
|
manganese/iron ABC transporter ATP-binding protein;
Pssm-ID: 185016 [Multi-domain] Cd Length: 272 Bit Score: 64.52 E-value: 1.33e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 2 ASISLRGVQKAYGDGAPVIRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLSIGGKIMNDVpAAQRGVAMV 81
Cdd:PRK15056 5 AGIVVNDVTVTWRNGHTALRDASFTVPGGSIAALVGVNGSGKSTLFKALMGFVRLASGKISILGQPTRQA-LQKNLVAYV 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 82 FQSYAL---FP-------HMTVFENMAFglklAKTPKEEIDRKVREA-ARVLQLEaLLERRPKALSGGQRQRVAIGRAIV 150
Cdd:PRK15056 84 PQSEEVdwsFPvlvedvvMMGRYGHMGW----LRRAKKRDRQIVTAAlARVDMVE-FRHRQIGELSGGQKKRVFLARAIA 158
|
170
....*....|....*.
gi 928002514 151 RQPGVFLFDEPLSNLD 166
Cdd:PRK15056 159 QQGQVILLDEPFTGVD 174
|
|
| SapD |
COG4170 |
ABC-type antimicrobial peptide export system, ATPase component SapD [Defense mechanisms]; |
23-224 |
1.81e-11 |
|
ABC-type antimicrobial peptide export system, ATPase component SapD [Defense mechanisms];
Pssm-ID: 443330 [Multi-domain] Cd Length: 331 Bit Score: 64.54 E-value: 1.81e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 23 VDLEIGENEFCVFLGPSGCGKSTLLCMIAGLED----LTDGDLSIGGKIMNDVPAAQR------GVAMVFQ--SYALFPH 90
Cdd:COG4170 26 VSLTLNEGEIRGLVGESGSGKSLIAKAICGITKdnwhVTADRFRWNGIDLLKLSPRERrkiigrEIAMIFQepSSCLDPS 105
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 91 MTVFENMAFGLklaktPKEEIDRKV--REAARVLQLEALLER------------RPKALSGGQRQRVAIGRAIVRQPGVF 156
Cdd:COG4170 106 AKIGDQLIEAI-----PSWTFKGKWwqRFKWRKKRAIELLHRvgikdhkdimnsYPHELTEGECQKVMIAMAIANQPRLL 180
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 928002514 157 LFDEPLSNLDATlrgqTRIEIARL---HKQFAKASVVYVTHDqIEAMT-LADKIVLLHAGKDTERyGSIAQI 224
Cdd:COG4170 181 IADEPTNAMEST----TQAQIFRLlarLNQLQGTSILLISHD-LESISqWADTITVLYCGQTVES-GPTEQI 246
|
|
| nikD |
PRK10418 |
nickel transporter ATP-binding protein NikD; Provisional |
18-237 |
2.44e-11 |
|
nickel transporter ATP-binding protein NikD; Provisional
Pssm-ID: 236688 [Multi-domain] Cd Length: 254 Bit Score: 63.18 E-value: 2.44e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 18 PVIRDVDLEIGENEFCVFLGPSGCGKStLLCMiAGLEDLTDGDLSIGGKIMND----VPAAQRG--VAMVFQS--YALFP 89
Cdd:PRK10418 17 PLVHGVSLTLQRGRVLALVGGSGSGKS-LTCA-AALGILPAGVRQTAGRVLLDgkpvAPCALRGrkIATIMQNprSAFNP 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 90 hmtvFENMA-----FGLKLAKTPKEEIDRKVREAARVLQLEALLERRPKALSGGQRQRVAIGRAIVRQPGVFLFDEPLSN 164
Cdd:PRK10418 95 ----LHTMHthareTCLALGKPADDATLTAALEAVGLENAARVLKLYPFEMSGGMLQRMMIALALLCEAPFIIADEPTTD 170
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 928002514 165 LDATLRGQTRIEIARLHKQFAkASVVYVTHDQIEAMTLADKIVLLHAGKdterygsIAQIGAPLELYHRPKSR 237
Cdd:PRK10418 171 LDVVAQARILDLLESIVQKRA-LGMLLVTHDMGVVARLADDVAVMSHGR-------IVEQGDVETLFNAPKHA 235
|
|
| PRK10522 |
PRK10522 |
multidrug transporter membrane component/ATP-binding component; Provisional |
4-221 |
6.64e-11 |
|
multidrug transporter membrane component/ATP-binding component; Provisional
Pssm-ID: 236707 [Multi-domain] Cd Length: 547 Bit Score: 63.84 E-value: 6.64e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 4 ISLRGVQKAYGDGAPVIRDVDLEIGENEfCVFL-GPSGCGKSTLLCMIAGLEDLTDGDLSIGGKI--MNDVPAAQRGVAM 80
Cdd:PRK10522 323 LELRNVTFAYQDNGFSVGPINLTIKRGE-LLFLiGGNGSGKSTLAMLLTGLYQPQSGEILLDGKPvtAEQPEDYRKLFSA 401
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 81 VFQSYALFPHMTVFENMAFGLKLAKTPKE--EIDRKVR-EAARVLQLEallerrpkaLSGGQRQRVAIGRAIVRQPGVFL 157
Cdd:PRK10522 402 VFTDFHLFDQLLGPEGKPANPALVEKWLErlKMAHKLElEDGRISNLK---------LSKGQKKRLALLLALAEERDILL 472
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 928002514 158 FDEPLSNLDATLRGQTRIEIARLHKQFAKaSVVYVTHDQiEAMTLADKIVLLHAGKDTERYGSI 221
Cdd:PRK10522 473 LDEWAADQDPHFRREFYQVLLPLLQEMGK-TIFAISHDD-HYFIHADRLLEMRNGQLSELTGEE 534
|
|
| phnK |
PRK11701 |
phosphonate C-P lyase system protein PhnK; Provisional |
5-216 |
1.54e-10 |
|
phosphonate C-P lyase system protein PhnK; Provisional
Pssm-ID: 183280 [Multi-domain] Cd Length: 258 Bit Score: 61.10 E-value: 1.54e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 5 SLRGVQKAYGDGAPvIRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLSIGGKIMNDVPAAQRGVA---MV 81
Cdd:PRK11701 8 SVRGLTKLYGPRKG-CRDVSFDLYPGEVLGIVGESGSGKTTLLNALSARLAPDAGEVHYRMRDGQLRDLYALSEAerrRL 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 82 FQSYALFPHmtvfENMAFGLKLAKTPKEEI--------DR---KVREAA-----RVLQLEALLERRPKALSGGQRQRVAI 145
Cdd:PRK11701 87 LRTEWGFVH----QHPRDGLRMQVSAGGNIgerlmavgARhygDIRATAgdwleRVEIDAARIDDLPTTFSGGMQQRLQI 162
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 928002514 146 GRAIVRQPGVFLFDEPLSNLD----ATLRGQTRIEIARLHkqfakASVVYVTHDQIEAMTLADKIVLLHAGKDTE 216
Cdd:PRK11701 163 ARNLVTHPRLVFMDEPTGGLDvsvqARLLDLLRGLVRELG-----LAVVIVTHDLAVARLLAHRLLVMKQGRVVE 232
|
|
| PRK10982 |
PRK10982 |
galactose/methyl galaxtoside transporter ATP-binding protein; Provisional |
6-213 |
2.23e-10 |
|
galactose/methyl galaxtoside transporter ATP-binding protein; Provisional
Pssm-ID: 182880 [Multi-domain] Cd Length: 491 Bit Score: 62.05 E-value: 2.23e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 6 LRGVQKAYgDGAPVIRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLSIGGKIMN---DVPAAQRGVAMVF 82
Cdd:PRK10982 1 MSNISKSF-PGVKALDNVNLKVRPHSIHALMGENGAGKSTLLKCLFGIYQKDSGSILFQGKEIDfksSKEALENGISMVH 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 83 QSYALFPHMTVFENMAFGLKLAKTPKEEIDRKVREAARVL-QLEALLERRPKA--LSGGQRQRVAIGRAIVRQPGVFLFD 159
Cdd:PRK10982 80 QELNLVLQRSVMDNMWLGRYPTKGMFVDQDKMYRDTKAIFdELDIDIDPRAKVatLSVSQMQMIEIAKAFSYNAKIVIMD 159
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 928002514 160 EPLSNLdatlrgqTRIEIARLHKQFAK-----ASVVYVTHDQIEAMTLADKIVLLHAGK 213
Cdd:PRK10982 160 EPTSSL-------TEKEVNHLFTIIRKlkergCGIVYISHKMEEIFQLCDEITILRDGQ 211
|
|
| OB_MalK |
pfam17912 |
MalK OB fold domain; This entry corresponds to one of two OB-fold domains found in the MalK ... |
244-298 |
3.13e-10 |
|
MalK OB fold domain; This entry corresponds to one of two OB-fold domains found in the MalK transport protein.
Pssm-ID: 465563 [Multi-domain] Cd Length: 53 Bit Score: 55.28 E-value: 3.13e-10
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 244 GSPRMNFLPGRVasvDAQGVIVTLDttleNVRVPVDGA-----ALEVAQPVTLGVRPEHL 298
Cdd:pfam17912 1 GSPPMNFLPATV---VEDGLLVLGG----GVTLPLPEGqvlalKLYVGKEVILGIRPEHI 53
|
|
| PRK13541 |
PRK13541 |
cytochrome c biogenesis protein CcmA; Provisional |
37-166 |
4.84e-10 |
|
cytochrome c biogenesis protein CcmA; Provisional
Pssm-ID: 184128 [Multi-domain] Cd Length: 195 Bit Score: 58.73 E-value: 4.84e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 37 GPSGCGKSTLLCMIAGLEDLTDGDLSIGGKIMNDVPAAQRGvaMVFQSYALFPHMTVFENMAFGLKLAKTPKeeidrKVR 116
Cdd:PRK13541 33 GANGCGKSSLLRMIAGIMQPSSGNIYYKNCNINNIAKPYCT--YIGHNLGLKLEMTVFENLKFWSEIYNSAE-----TLY 105
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|
gi 928002514 117 EAARVLQLEALLERRPKALSGGQRQRVAIGRAIVRQPGVFLFDEPLSNLD 166
Cdd:PRK13541 106 AAIHYFKLHDLLDEKCYSLSSGMQKIVAIARLIACQSDLWLLDEVETNLS 155
|
|
| PTZ00243 |
PTZ00243 |
ABC transporter; Provisional |
3-238 |
1.29e-09 |
|
ABC transporter; Provisional
Pssm-ID: 240327 [Multi-domain] Cd Length: 1560 Bit Score: 60.18 E-value: 1.29e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 3 SISLRGVQKAYGDGAP-VIRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLSIGGKimnDVPA-----AQR 76
Cdd:PTZ00243 1308 SLVFEGVQMRYREGLPlVLRGVSFRIAPREKVGIVGRTGSGKSTLLLTFMRMVEVCGGEIRVNGR---EIGAyglreLRR 1384
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 77 GVAMVFQSYALFPHmTVFENM-AFglkLAKTPKeeidrkvrEAARVLQLEALLER--------RPKALSG------GQRQ 141
Cdd:PTZ00243 1385 QFSMIPQDPVLFDG-TVRQNVdPF---LEASSA--------EVWAALELVGLRERvasesegiDSRVLEGgsnysvGQRQ 1452
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 142 RVAIGRAIV-RQPGVFLFDEPLSNLDATLRGQTRieiARLHKQFAKASVVYVTHdQIEAMTLADKIVLLHagkdterYGS 220
Cdd:PTZ00243 1453 LMCMARALLkKGSGFILMDEATANIDPALDRQIQ---ATVMSAFSAYTVITIAH-RLHTVAQYDKIIVMD-------HGA 1521
|
250
....*....|....*...
gi 928002514 221 IAQIGAPLELYHRPKSRF 238
Cdd:PTZ00243 1522 VAEMGSPRELVMNRQSIF 1539
|
|
| PRK13538 |
PRK13538 |
cytochrome c biogenesis heme-transporting ATPase CcmA; |
15-167 |
1.86e-09 |
|
cytochrome c biogenesis heme-transporting ATPase CcmA;
Pssm-ID: 184125 [Multi-domain] Cd Length: 204 Bit Score: 57.12 E-value: 1.86e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 15 DGAPVIRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLSIGGKIMNdvpaAQRGVamvFQSYALF------ 88
Cdd:PRK13538 12 DERILFSGLSFTLNAGELVQIEGPNGAGKTSLLRILAGLARPDAGEVLWQGEPIR----RQRDE---YHQDLLYlghqpg 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 89 --PHMTVFENMAFGLKLAktpkeeidRKVREAARVLQLEAL-LERR---P-KALSGGQRQRVAIGRAIVRQPGVFLFDEP 161
Cdd:PRK13538 85 ikTELTALENLRFYQRLH--------GPGDDEALWEALAQVgLAGFedvPvRQLSAGQQRRVALARLWLTRAPLWILDEP 156
|
....*.
gi 928002514 162 LSNLDA 167
Cdd:PRK13538 157 FTAIDK 162
|
|
| sufC |
PRK09580 |
cysteine desulfurase ATPase component; Reviewed |
15-166 |
1.91e-09 |
|
cysteine desulfurase ATPase component; Reviewed
Pssm-ID: 181965 [Multi-domain] Cd Length: 248 Bit Score: 57.49 E-value: 1.91e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 15 DGAPVIRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLED--LTDGDLSIGGKIMNDVPAAQR---GVAMVFQSYALFP 89
Cdd:PRK09580 12 EDKAILRGLNLEVRPGEVHAIMGPNGSGKSTLSATLAGREDyeVTGGTVEFKGKDLLELSPEDRageGIFMAFQYPVEIP 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 90 HMT--VFENMAFGLKLAKTPKEEIDR-----KVREAARVLQLEA-LLERRPK-ALSGGQRQRVAIGRAIVRQPGVFLFDE 160
Cdd:PRK09580 92 GVSnqFFLQTALNAVRSYRGQEPLDRfdfqdLMEEKIALLKMPEdLLTRSVNvGFSGGEKKRNDILQMAVLEPELCILDE 171
|
....*.
gi 928002514 161 PLSNLD 166
Cdd:PRK09580 172 SDSGLD 177
|
|
| PRK13543 |
PRK13543 |
heme ABC exporter ATP-binding protein CcmA; |
15-185 |
5.29e-09 |
|
heme ABC exporter ATP-binding protein CcmA;
Pssm-ID: 184129 [Multi-domain] Cd Length: 214 Bit Score: 56.01 E-value: 5.29e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 15 DGAPVIRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLSIGGKimnDVPAAQRGVAMVFQSY--ALFPHMT 92
Cdd:PRK13543 22 NEEPVFGPLDFHVDAGEALLVQGDNGAGKTTLLRVLAGLLHVESGQIQIDGK---TATRGDRSRFMAYLGHlpGLKADLS 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 93 VFENMAF-----GLKLAKTPKeeidrkvrEAARVLQLEALLERRPKALSGGQRQRVAIGRAIVRQPGVFLFDEPLSNLDa 167
Cdd:PRK13543 99 TLENLHFlcglhGRRAKQMPG--------SALAIVGLAGYEDTLVRQLSAGQKKRLALARLWLSPAPLWLLDEPYANLD- 169
|
170 180
....*....|....*....|.
gi 928002514 168 tLRGQT---RIEIARLHKQFA 185
Cdd:PRK13543 170 -LEGITlvnRMISAHLRGGGA 189
|
|
| PTZ00265 |
PTZ00265 |
multidrug resistance protein (mdr1); Provisional |
19-166 |
1.70e-08 |
|
multidrug resistance protein (mdr1); Provisional
Pssm-ID: 240339 [Multi-domain] Cd Length: 1466 Bit Score: 56.58 E-value: 1.70e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 19 VIRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLsiggkIMND--------VPAAQRGVAMVFQSYALFPH 90
Cdd:PTZ00265 400 IYKDLNFTLTEGKTYAFVGESGCGKSTILKLIERLYDPTEGDI-----IINDshnlkdinLKWWRSKIGVVSQDPLLFSN 474
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 91 mTVFENMAFGLKLAK-----------------------------------------TPKEEIDRK-----------VREA 118
Cdd:PTZ00265 475 -SIKNNIKYSLYSLKdlealsnyynedgndsqenknkrnscrakcagdlndmsnttDSNELIEMRknyqtikdsevVDVS 553
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 928002514 119 ARVL----------QLEALLERRPKALSGGQRQRVAIGRAIVRQPGVFLFDEPLSNLD 166
Cdd:PTZ00265 554 KKVLihdfvsalpdKYETLVGSNASKLSGGQKQRISIARAIIRNPKILILDEATSSLD 611
|
|
| PRK15093 |
PRK15093 |
peptide ABC transporter ATP-binding protein SapD; |
132-259 |
2.53e-08 |
|
peptide ABC transporter ATP-binding protein SapD;
Pssm-ID: 185049 [Multi-domain] Cd Length: 330 Bit Score: 55.19 E-value: 2.53e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 132 PKALSGGQRQRVAIGRAIVRQPGVFLFDEPLSNLDATLRGQTRIEIARLHkQFAKASVVYVTHDQIEAMTLADKIVLLHA 211
Cdd:PRK15093 156 PYELTEGECQKVMIAIALANQPRLLIADEPTNAMEPTTQAQIFRLLTRLN-QNNNTTILLISHDLQMLSQWADKINVLYC 234
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|...
gi 928002514 212 GKDTERYGSIAQIGAPLELYHRPKSRFVAGFiGSP-----RMNFLPGRVASVD 259
Cdd:PRK15093 235 GQTVETAPSKELVTTPHHPYTQALIRAIPDF-GSAmphksRLNTLPGAIPLLE 286
|
|
| ABC_RNaseL_inhibitor |
cd03222 |
ATP-binding cassette domain of RNase L inhibitor; The ABC ATPase RNase L inhibitor (RLI) is a ... |
26-210 |
3.10e-08 |
|
ATP-binding cassette domain of RNase L inhibitor; The ABC ATPase RNase L inhibitor (RLI) is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI's are not transport proteins, and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLI's have an N-terminal Fe-S domain and two nucleotide-binding domains, which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.
Pssm-ID: 213189 [Multi-domain] Cd Length: 177 Bit Score: 52.96 E-value: 3.10e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 26 EIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLSIGGkimndvpaaqrgvamvfqsyalfphmtvfenmafgLKLAK 105
Cdd:cd03222 21 VVKEGEVIGIVGPNGTGKTTAVKILAGQLIPNGDNDEWDG-----------------------------------ITPVY 65
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 106 TPkEEIDrkvreaarvlqleallerrpkaLSGGQRQRVAIGRAIVRQPGVFLFDEPLSNLDAtlrgQTRIEIARLHKQF- 184
Cdd:cd03222 66 KP-QYID----------------------LSGGELQRVAIAAALLRNATFYLFDEPSAYLDI----EQRLNAARAIRRLs 118
|
170 180
....*....|....*....|....*...
gi 928002514 185 --AKASVVYVTHDQIEAMTLADKIVLLH 210
Cdd:cd03222 119 eeGKKTALVVEHDLAVLDYLSDRIHVFE 146
|
|
| ycf16 |
CHL00131 |
sulfate ABC transporter protein; Validated |
11-196 |
3.35e-08 |
|
sulfate ABC transporter protein; Validated
Pssm-ID: 214372 [Multi-domain] Cd Length: 252 Bit Score: 53.88 E-value: 3.35e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 11 KAYGDGAPVIRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLE--DLTDGDLSIGGKIMNDVPA---AQRGVAMVFQSY 85
Cdd:CHL00131 14 HASVNENEILKGLNLSINKGEIHAIMGPNGSGKSTLSKVIAGHPayKILEGDILFKGESILDLEPeerAHLGIFLAFQYP 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 86 ALFPHMTV--FENMAFGLKLAKTPKEEID-----RKVREAARVLQLEA-LLERR-PKALSGGQRQRVAIGRAIVRQPGVF 156
Cdd:CHL00131 94 IEIPGVSNadFLRLAYNSKRKFQGLPELDpleflEIINEKLKLVGMDPsFLSRNvNEGFSGGEKKRNEILQMALLDSELA 173
|
170 180 190 200
....*....|....*....|....*....|....*....|...
gi 928002514 157 LFDEPLSNLDA-TLRgqtriEIARLHKQFAKA--SVVYVTHDQ 196
Cdd:CHL00131 174 ILDETDSGLDIdALK-----IIAEGINKLMTSenSIILITHYQ 211
|
|
| ABC2_perm_RbbA |
NF033858 |
ribosome-associated ATPase/putative transporter RbbA; |
4-161 |
3.46e-08 |
|
ribosome-associated ATPase/putative transporter RbbA;
Pssm-ID: 468210 [Multi-domain] Cd Length: 907 Bit Score: 55.52 E-value: 3.46e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 4 ISLRGVQKAYGDgAPVIRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLSIGGKIMNDvpAAQRgvAMVFQ 83
Cdd:NF033858 2 ARLEGVSHRYGK-TVALDDVSLDIPAGCMVGLIGPDGVGKSSLLSLIAGARKIQQGRVEVLGGDMAD--ARHR--RAVCP 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 84 SYA---------LFPHMTVFENMAFGLKLAKTPKEEIDRKVREAARVLQLEALLERRPKALSGGQRQRVAIGRAIVRQPG 154
Cdd:NF033858 77 RIAympqglgknLYPTLSVFENLDFFGRLFGQDAAERRRRIDELLRATGLAPFADRPAGKLSGGMKQKLGLCCALIHDPD 156
|
....*..
gi 928002514 155 VFLFDEP 161
Cdd:NF033858 157 LLILDEP 163
|
|
| TOBE_2 |
pfam08402 |
TOBE domain; The TOBE domain (Transport-associated OB) always occurs as a dimer as the ... |
291-366 |
3.84e-08 |
|
TOBE domain; The TOBE domain (Transport-associated OB) always occurs as a dimer as the C-terminal strand of each domain is supplied by the partner. Probably involved in the recognition of small ligands such as molybdenum and sulphate. Found in ABC transporters immediately after the ATPase domain. In this family a strong RPE motif is found at the presumed N-terminus of the domain.
Pssm-ID: 462465 [Multi-domain] Cd Length: 73 Bit Score: 49.93 E-value: 3.84e-08
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 928002514 291 LGVRPEHLEFIDtsslqDEAVLTRTVSLVEQLGEHSYVHLDQPGGFTLIAKAPGDTH--LAPGDRAHLRVPRHATHLF 366
Cdd:pfam08402 1 LAIRPEKIRLAA-----AANGLSGTVTDVEYLGDHTRYHVELAGGEELVVRVPNAHArpPAPGDRVGLGWDPEDAHVL 73
|
|
| ABCC_CFTR2 |
cd03289 |
ATP-binding cassette domain 2 of CFTR,subfamily C; The cystic fibrosis transmembrane regulator ... |
15-257 |
4.77e-08 |
|
ATP-binding cassette domain 2 of CFTR,subfamily C; The cystic fibrosis transmembrane regulator (CFTR), the product of the gene mutated in patients with cystic fibrosis, has adapted the ABC transporter structural motif to form a tightly regulated anion channel at the apical surface of many epithelia. Use of the term assembly of a functional ion channel implies the coming together of subunits or at least smaller not-yet functional components of the active whole. In fact, on the basis of current knowledge only the CFTR polypeptide itself is required to form an ATP- and protein kinase A-dependent low-conductance chloride channel of the type present in the apical membrane of many epithelial cells. CFTR displays the typical organization (IM-ABC)2 and carries a characteristic hydrophilic R-domain that separates IM1-ABC1 from IM2-ABC2.
Pssm-ID: 213256 [Multi-domain] Cd Length: 275 Bit Score: 53.70 E-value: 4.77e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 15 DGAPVIRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDlTDGDLSIGGKIMNDVPAAQ--RGVAMVFQSYALFPHmT 92
Cdd:cd03289 15 GGNAVLENISFSISPGQRVGLLGRTGSGKSTLLSAFLRLLN-TEGDIQIDGVSWNSVPLQKwrKAFGVIPQKVFIFSG-T 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 93 VFENMAfglKLAKTPKEEIDRKVREAARVL-------QLEALLERRPKALSGGQRQRVAIGRAIVRQPGVFLFDEPLSNL 165
Cdd:cd03289 93 FRKNLD---PYGKWSDEEIWKVAEEVGLKSvieqfpgQLDFVLVDGGCVLSHGHKQLMCLARSVLSKAKILLLDEPSAHL 169
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 166 DAtlrgqTRIEIAR--LHKQFAKASVVYVTHdQIEAMTLADKIVLLHAGKdTERYGSIAQIgaplelyHRPKSRFVAGFI 243
Cdd:cd03289 170 DP-----ITYQVIRktLKQAFADCTVILSEH-RIEAMLECQRFLVIEENK-VRQYDSIQKL-------LNEKSHFKQAIS 235
|
250
....*....|....
gi 928002514 244 GSPRMNFLPGRVAS 257
Cdd:cd03289 236 PSDRLKLFPRRNSS 249
|
|
| PRK10762 |
PRK10762 |
D-ribose transporter ATP binding protein; Provisional |
18-213 |
5.12e-08 |
|
D-ribose transporter ATP binding protein; Provisional
Pssm-ID: 236755 [Multi-domain] Cd Length: 501 Bit Score: 54.62 E-value: 5.12e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 18 PVIRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLSIGGKIMNDVpAAQRGVA--MVFQSY-----ALFPH 90
Cdd:PRK10762 266 PGVNDVSFTLRKGEILGVSGLMGAGRTELMKVLYGALPRTSGYVTLDGHEVVTR-SPQDGLAngIVYISEdrkrdGLVLG 344
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 91 MTVFENMAF-GLKLAKTPKEEIDRKvREAARVLQLEAL-------LERRPKALSGGQRQRVAIGRAIVRQPGVFLFDEPL 162
Cdd:PRK10762 345 MSVKENMSLtALRYFSRAGGSLKHA-DEQQAVSDFIRLfniktpsMEQAIGLLSGGNQQKVAIARGLMTRPKVLILDEPT 423
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 928002514 163 SNLDAtlrGQTRiEIARLHKQFAKA--SVVYVTHDQIEAMTLADKIVLLHAGK 213
Cdd:PRK10762 424 RGVDV---GAKK-EIYQLINQFKAEglSIILVSSEMPEVLGMSDRILVMHEGR 472
|
|
| PRK11819 |
PRK11819 |
putative ABC transporter ATP-binding protein; Reviewed |
4-195 |
5.70e-08 |
|
putative ABC transporter ATP-binding protein; Reviewed
Pssm-ID: 236992 [Multi-domain] Cd Length: 556 Bit Score: 54.35 E-value: 5.70e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 4 ISLRGVQKAYGDGApVIRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLSIGgkimndvPAAQrgVAMVFQ 83
Cdd:PRK11819 325 IEAENLSKSFGDRL-LIDDLSFSLPPGGIVGIIGPNGAGKSTLFKMITGQEQPDSGTIKIG-------ETVK--LAYVDQ 394
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 84 SY-ALFPHMTVFENMAFGLKLAKTPKEEIdrkvreAARvlqleALLER----------RPKALSGGQRQRVAIGRaIVRQ 152
Cdd:PRK11819 395 SRdALDPNKTVWEEISGGLDIIKVGNREI------PSR-----AYVGRfnfkggdqqkKVGVLSGGERNRLHLAK-TLKQ 462
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
gi 928002514 153 PG-VFLFDEPLSNLDA-TLRGqtrIEIARLhkQFAKASVVyVTHD 195
Cdd:PRK11819 463 GGnVLLLDEPTNDLDVeTLRA---LEEALL--EFPGCAVV-ISHD 501
|
|
| PRK10938 |
PRK10938 |
putative molybdenum transport ATP-binding protein ModF; Provisional |
105-183 |
6.83e-08 |
|
putative molybdenum transport ATP-binding protein ModF; Provisional
Pssm-ID: 182852 [Multi-domain] Cd Length: 490 Bit Score: 54.25 E-value: 6.83e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 105 KTPKEEIDRKVREAARVLQL------EALLERRPKALSGGQRQRVAIGRAIVRQPGVFLFDEPLSNLDATLRGQTRIEIA 178
Cdd:PRK10938 100 RTTAEIIQDEVKDPARCEQLaqqfgiTALLDRRFKYLSTGETRKTLLCQALMSEPDLLILDEPFDGLDVASRQQLAELLA 179
|
....*
gi 928002514 179 RLHKQ 183
Cdd:PRK10938 180 SLHQS 184
|
|
| CFTR_protein |
TIGR01271 |
cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis ... |
15-224 |
9.04e-08 |
|
cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis fibrosis transmembrane conductor regulator (CFTR) in eukaryotes. The principal role of this protein is chloride ion conductance. The protein is predicted to consist of 12 transmembrane domains. Mutations or lesions in the genetic loci have been linked to the aetiology of asthma, bronchiectasis, chronic obstructive pulmonary disease etc. Disease-causing mutations have been studied by 36Cl efflux assays in vitro cell cultures and electrophysiology, all of which point to the impairment of chloride channel stability and not the biosynthetic processing per se. [Transport and binding proteins, Anions]
Pssm-ID: 273530 [Multi-domain] Cd Length: 1490 Bit Score: 54.15 E-value: 9.04e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 15 DGAPVIRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDlTDGDLSIGGKIMNDVPAAQRGVAmvfqsYALFPHMTVF 94
Cdd:TIGR01271 1230 AGRAVLQDLSFSVEGGQRVGLLGRTGSGKSTLLSALLRLLS-TEGEIQIDGVSWNSVTLQTWRKA-----FGVIPQKVFI 1303
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 95 ENMAFGLKLakTPKEEI-DRKVREAARVLQLEALLERRPK-----------ALSGGQRQRVAIGRAIVRQPGVFLFDEPL 162
Cdd:TIGR01271 1304 FSGTFRKNL--DPYEQWsDEEIWKVAEEVGLKSVIEQFPDkldfvlvdggyVLSNGHKQLMCLARSILSKAKILLLDEPS 1381
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 928002514 163 SNLDAtlrgqTRIEIAR--LHKQFAKASVVYVTHdQIEAMtLADKIVLLHAGKDTERYGSIAQI 224
Cdd:TIGR01271 1382 AHLDP-----VTLQIIRktLKQSFSNCTVILSEH-RVEAL-LECQQFLVIEGSSVKQYDSIQKL 1438
|
|
| hmuV |
PRK13547 |
heme ABC transporter ATP-binding protein; |
15-212 |
9.80e-08 |
|
heme ABC transporter ATP-binding protein;
Pssm-ID: 184132 [Multi-domain] Cd Length: 272 Bit Score: 52.91 E-value: 9.80e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 15 DGAPVIRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGleDLTD----------GDLSIGGKIMNDVPA---AQRGVAMV 81
Cdd:PRK13547 12 RHRAILRDLSLRIEPGRVTALLGRNGAGKSTLLKALAG--DLTGggaprgarvtGDVTLNGEPLAAIDAprlARLRAVLP 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 82 FQSYALFPhMTVFENMAFGLKLAKTPKEEIDRKVRE-AARVLQL---EALLERRPKALSGGQRQRVAIGRAI-------- 149
Cdd:PRK13547 90 QAAQPAFA-FSAREIVLLGRYPHARRAGALTHRDGEiAWQALALagaTALVGRDVTTLSGGELARVQFARVLaqlwpphd 168
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 928002514 150 -VRQPGVFLFDEPLSNLDATLRGQTRIEIARLHKQFaKASVVYVTHDQIEAMTLADKIVLLHAG 212
Cdd:PRK13547 169 aAQPPRYLLLDEPTAALDLAHQHRLLDTVRRLARDW-NLGVLAIVHDPNLAARHADRIAMLADG 231
|
|
| znuC |
PRK09544 |
high-affinity zinc transporter ATPase; Reviewed |
4-209 |
1.22e-07 |
|
high-affinity zinc transporter ATPase; Reviewed
Pssm-ID: 181939 [Multi-domain] Cd Length: 251 Bit Score: 52.42 E-value: 1.22e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 4 ISLRGVQKAYGDGApVIRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLSIGGKIMndvpaaqrgVAMVFQ 83
Cdd:PRK09544 5 VSLENVSVSFGQRR-VLSDVSLELKPGKILTLLGPNGAGKSTLVRVVLGLVAPDEGVIKRNGKLR---------IGYVPQ 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 84 SYALFPHM--TV--FENMAFGLKLAKtpkeeidrkVREAARVLQLEALLERRPKALSGGQRQRVAIGRAIVRQPGVFLFD 159
Cdd:PRK09544 75 KLYLDTTLplTVnrFLRLRPGTKKED---------ILPALKRVQAGHLIDAPMQKLSGGETQRVLLARALLNRPQLLVLD 145
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 928002514 160 EPLSNLDatLRGQTRIE--IARLHKQFAKAsVVYVTHDQIEAMTLADKIVLL 209
Cdd:PRK09544 146 EPTQGVD--VNGQVALYdlIDQLRRELDCA-VLMVSHDLHLVMAKTDEVLCL 194
|
|
| PLN03140 |
PLN03140 |
ABC transporter G family member; Provisional |
36-167 |
1.46e-07 |
|
ABC transporter G family member; Provisional
Pssm-ID: 215599 [Multi-domain] Cd Length: 1470 Bit Score: 53.70 E-value: 1.46e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 36 LGPSGCGKSTLLCMIAGLED--LTDGDLSIGGkimndVPAAQRGVAMVF----QSYALFPHMTVFENMAFG--LKLAK-T 106
Cdd:PLN03140 912 MGVSGAGKTTLMDVLAGRKTggYIEGDIRISG-----FPKKQETFARISgyceQNDIHSPQVTVRESLIYSafLRLPKeV 986
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 928002514 107 PKEEIDRKVREAARVLQLEALLER---RP--KALSGGQRQRVAIGRAIVRQPGVFLFDEPLSNLDA 167
Cdd:PLN03140 987 SKEEKMMFVDEVMELVELDNLKDAivgLPgvTGLSTEQRKRLTIAVELVANPSIIFMDEPTSGLDA 1052
|
|
| ABC_Rad50 |
cd03240 |
ATP-binding cassette domain of Rad50; The catalytic domains of Rad50 are similar to the ... |
34-207 |
2.03e-07 |
|
ATP-binding cassette domain of Rad50; The catalytic domains of Rad50 are similar to the ATP-binding cassette of ABC transporters, but are not associated with membrane-spanning domains. The conserved ATP-binding motifs common to Rad50 and the ABC transporter family include the Walker A and Walker B motifs, the Q loop, a histidine residue in the switch region, a D-loop, and a conserved LSGG sequence. This conserved sequence, LSGG, is the most specific and characteristic motif of this family and is thus known as the ABC signature sequence.
Pssm-ID: 213207 [Multi-domain] Cd Length: 204 Bit Score: 51.07 E-value: 2.03e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 34 VFLGPSGCGKSTLL-CMIAGLEdltdGDLSIGGKIMNDVP-----AAQRG-VAMVFQS-----YALFPHMTVFENMAFgl 101
Cdd:cd03240 26 LIVGQNGAGKTTIIeALKYALT----GELPPNSKGGAHDPklireGEVRAqVKLAFENangkkYTITRSLAILENVIF-- 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 102 klakTPKEEIDrkvreaarvlqleALLERRPKALSGGQRQ------RVAIGRAIVRQPGVFLFDEPLSNLDATLRGQTRI 175
Cdd:cd03240 100 ----CHQGESN-------------WPLLDMRGRCSGGEKVlasliiRLALAETFGSNCGILALDEPTTNLDEENIEESLA 162
|
170 180 190
....*....|....*....|....*....|..
gi 928002514 176 EIARLHKQFAKASVVYVTHDQiEAMTLADKIV 207
Cdd:cd03240 163 EIIEERKSQKNFQLIVITHDE-ELVDAADHIY 193
|
|
| PRK10982 |
PRK10982 |
galactose/methyl galaxtoside transporter ATP-binding protein; Provisional |
18-213 |
3.22e-07 |
|
galactose/methyl galaxtoside transporter ATP-binding protein; Provisional
Pssm-ID: 182880 [Multi-domain] Cd Length: 491 Bit Score: 52.04 E-value: 3.22e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 18 PVIRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLSIGGKIMND---VPAAQRGVAMVFQ---SYALFPHM 91
Cdd:PRK10982 262 PSIRDVSFDLHKGEILGIAGLVGAKRTDIVETLFGIREKSAGTITLHGKKINNhnaNEAINHGFALVTEerrSTGIYAYL 341
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 92 TV-FENMAFGLKLAKTPKEEIDRKVREAARVLQLEALLERRPK------ALSGGQRQRVAIGRAIVRQPGVFLFDEPLSN 164
Cdd:PRK10982 342 DIgFNSLISNIRNYKNKVGLLDNSRMKSDTQWVIDSMRVKTPGhrtqigSLSGGNQQKVIIGRWLLTQPEILMLDEPTRG 421
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 928002514 165 LDATlrgqTRIEIARLHKQFAK--ASVVYVTHDQIEAMTLADKIVLLHAGK 213
Cdd:PRK10982 422 IDVG----AKFEIYQLIAELAKkdKGIIIISSEMPELLGITDRILVMSNGL 468
|
|
| xylG |
TIGR02633 |
D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose ... |
20-213 |
3.57e-07 |
|
D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose isomerase and xylulokinase enzymes for xylose utilization. Members of this protein family are the ATP-binding cassette (ABC) subunit of the known or predicted high-affinity xylose ABC transporter for xylose import. These genes, which closely resemble other sugar transport ABC transporter genes, typically are encoded near xylose utilization enzymes and regulatory proteins. Note that this form of the transporter contains two copies of the ABC transporter domain (pfam00005). [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]
Pssm-ID: 131681 [Multi-domain] Cd Length: 500 Bit Score: 52.13 E-value: 3.57e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 20 IRDVDLEIGENEFCVFLGPSGCGKSTLL-CMIAGLEDLTDGDLSIGGK---IMNDVPAAQRGVAMVFQS---YALFPHMT 92
Cdd:TIGR02633 276 VDDVSFSLRRGEILGVAGLVGAGRTELVqALFGAYPGKFEGNVFINGKpvdIRNPAQAIRAGIAMVPEDrkrHGIVPILG 355
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 93 VFENMAFGLKLAKTPKEEID-----RKVREAARVLQLEALLERRPKA-LSGGQRQRVAIGRAIVRQPGVFLFDEPLSNLD 166
Cdd:TIGR02633 356 VGKNITLSVLKSFCFKMRIDaaaelQIIGSAIQRLKVKTASPFLPIGrLSGGNQQKAVLAKMLLTNPRVLILDEPTRGVD 435
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 928002514 167 ATlrgqTRIEIARLHKQFAK--ASVVYVTHDQIEAMTLADKIVLLHAGK 213
Cdd:TIGR02633 436 VG----AKYEIYKLINQLAQegVAIIVVSSELAEVLGLSDRVLVIGEGK 480
|
|
| PLN03232 |
PLN03232 |
ABC transporter C family member; Provisional |
3-238 |
8.64e-07 |
|
ABC transporter C family member; Provisional
Pssm-ID: 215640 [Multi-domain] Cd Length: 1495 Bit Score: 51.13 E-value: 8.64e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 3 SISLRGVQKAYGDG-APVIRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLSIGG----KI-MNDVpaaQR 76
Cdd:PLN03232 1234 SIKFEDVHLRYRPGlPPVLHGLSFFVSPSEKVGVVGRTGAGKSSMLNALFRIVELEKGRIMIDDcdvaKFgLTDL---RR 1310
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 77 GVAMVFQSYALFPHMTVFENMAFglklaktpKEEIDRKVREAARVLQLEALLERRPKAL-----------SGGQRQRVAI 145
Cdd:PLN03232 1311 VLSIIPQSPVLFSGTVRFNIDPF--------SEHNDADLWEALERAHIKDVIDRNPFGLdaevseggenfSVGQRQLLSL 1382
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 146 GRAIVRQPGVFLFDEPLSNLDatLRGQTRIEiARLHKQFAKASVVYVTHdQIEAMTLADKIVLLHAGKdterygsIAQIG 225
Cdd:PLN03232 1383 ARALLRRSKILVLDEATASVD--VRTDSLIQ-RTIREEFKSCTMLVIAH-RLNTIIDCDKILVLSSGQ-------VLEYD 1451
|
250
....*....|...
gi 928002514 226 APLELYHRPKSRF 238
Cdd:PLN03232 1452 SPQELLSRDTSAF 1464
|
|
| PRK11147 |
PRK11147 |
ABC transporter ATPase component; Reviewed |
37-166 |
1.29e-06 |
|
ABC transporter ATPase component; Reviewed
Pssm-ID: 236861 [Multi-domain] Cd Length: 635 Bit Score: 50.33 E-value: 1.29e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 37 GPSGCGKSTLL-CMIAGLEDlTDGDLSIGGKImndvpaaqrGVAMvFQSY--ALFPHMTVFENMAFGlklaktpKEE--I 111
Cdd:PRK11147 352 GPNGCGKTTLLkLMLGQLQA-DSGRIHCGTKL---------EVAY-FDQHraELDPEKTVMDNLAEG-------KQEvmV 413
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 112 DRKVREAARVLQlEALLE----RRP-KALSGGQRQRVAIGRAIVRQPGVFLFDEPLSNLD 166
Cdd:PRK11147 414 NGRPRHVLGYLQ-DFLFHpkraMTPvKALSGGERNRLLLARLFLKPSNLLILDEPTNDLD 472
|
|
| PRK13546 |
PRK13546 |
teichoic acids export ABC transporter ATP-binding subunit TagH; |
20-224 |
7.73e-06 |
|
teichoic acids export ABC transporter ATP-binding subunit TagH;
Pssm-ID: 184131 [Multi-domain] Cd Length: 264 Bit Score: 47.12 E-value: 7.73e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 20 IRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLSIGGKimndvpaaqrgVAMVFQSYALFPHMTVFENMAF 99
Cdd:PRK13546 40 LDDISLKAYEGDVIGLVGINGSGKSTLSNIIGGSLSPTVGKVDRNGE-----------VSVIAISAGLSGQLTGIENIEF 108
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 100 GLKLAKTPKEEIDRKVREAARVLQLEALLERRPKALSGGQRQRVAIGRAIVRQPGVFLFDEPLSNLDATLRGQTRIEIAR 179
Cdd:PRK13546 109 KMLCMGFKRKEIKAMTPKIIEFSELGEFIYQPVKKYSSGMRAKLGFSINITVNPDILVIDEALSVGDQTFAQKCLDKIYE 188
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
gi 928002514 180 LHKQfaKASVVYVTHDQIEAMTLADKIVLLHAGKDTErYGSIAQI 224
Cdd:PRK13546 189 FKEQ--NKTIFFVSHNLGQVRQFCTKIAWIEGGKLKD-YGELDDV 230
|
|
| PvdE |
COG4615 |
ABC-type siderophore export system, fused ATPase and permease components [Inorganic ion ... |
3-160 |
1.02e-05 |
|
ABC-type siderophore export system, fused ATPase and permease components [Inorganic ion transport and metabolism];
Pssm-ID: 443659 [Multi-domain] Cd Length: 547 Bit Score: 47.49 E-value: 1.02e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 3 SISLRGVQKAY----GDGAPVIRDVDLEI--GEnefCVFL-GPSGCGKSTLLCMIAGLEDLTDGDLSIGGKImndVPAAQ 75
Cdd:COG4615 327 TLELRGVTYRYpgedGDEGFTLGPIDLTIrrGE---LVFIvGGNGSGKSTLAKLLTGLYRPESGEILLDGQP---VTADN 400
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 76 RGV-----AMVFQSYALFPHMtvfenmaFGLKLAKTPKE--------EIDRKVREAARVLQleallerrPKALSGGQRQR 142
Cdd:COG4615 401 REAyrqlfSAVFSDFHLFDRL-------LGLDGEADPARarellerlELDHKVSVEDGRFS--------TTDLSQGQRKR 465
|
170
....*....|....*...
gi 928002514 143 VAIGRAIVRQPGVFLFDE 160
Cdd:COG4615 466 LALLVALLEDRPILVFDE 483
|
|
| PRK13549 |
PRK13549 |
xylose transporter ATP-binding subunit; Provisional |
58-213 |
1.07e-05 |
|
xylose transporter ATP-binding subunit; Provisional
Pssm-ID: 184134 [Multi-domain] Cd Length: 506 Bit Score: 47.23 E-value: 1.07e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 58 DGDLSIGGK---IMNDVPAAQRGVAMVFQS---YALFPHMTVFENM--------AFGLKL-----AKTPKEEIDR-KVRE 117
Cdd:PRK13549 317 EGEIFIDGKpvkIRNPQQAIAQGIAMVPEDrkrDGIVPVMGVGKNItlaaldrfTGGSRIddaaeLKTILESIQRlKVKT 396
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 118 AArvlqlealLERRPKALSGGQRQRVAIGRAIVRQPGVFLFDEPLSNLDATlrgqTRIEIARLHKQFAKA--SVVYVTHD 195
Cdd:PRK13549 397 AS--------PELAIARLSGGNQQKAVLAKCLLLNPKILILDEPTRGIDVG----AKYEIYKLINQLVQQgvAIIVISSE 464
|
170
....*....|....*...
gi 928002514 196 QIEAMTLADKIVLLHAGK 213
Cdd:PRK13549 465 LPEVLGLSDRVLVMHEGK 482
|
|
| ABC_UvrA |
cd03238 |
ATP-binding cassette domain of the excision repair protein UvrA; Nucleotide excision repair in ... |
20-220 |
1.28e-05 |
|
ATP-binding cassette domain of the excision repair protein UvrA; Nucleotide excision repair in eubacteria is a process that repairs DNA damage by the removal of a 12-13-mer oligonucleotide containing the lesion. Recognition and cleavage of the damaged DNA is a multistep ATP-dependent reaction that requires the UvrA, UvrB, and UvrC proteins. Both UvrA and UvrB are ATPases, with UvrA having two ATP binding sites, which have the characteristic signature of the family of ABC proteins, and UvrB having one ATP binding site that is structurally related to that of helicases.
Pssm-ID: 213205 [Multi-domain] Cd Length: 176 Bit Score: 45.39 E-value: 1.28e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 20 IRDVDLEIGENEFCVFLGPSGCGKSTLL--CMIAGLEDLTDGDLSiggkimndvpaaqrgvamvfqsyALFPHMTVFenm 97
Cdd:cd03238 11 LQNLDVSIPLNVLVVVTGVSGSGKSTLVneGLYASGKARLISFLP-----------------------KFSRNKLIF--- 64
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 98 afglklaktpkeeIDrkvreaarvlQLEAL---------LERRPKALSGGQRQRVAIGRAIVRQPG--VFLFDEPLSNLD 166
Cdd:cd03238 65 -------------ID----------QLQFLidvglgyltLGQKLSTLSGGELQRVKLASELFSEPPgtLFILDEPSTGLH 121
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 928002514 167 ATLRGQTRIEIARLHKQfaKASVVYVTHDqIEAMTLADKIVLLhaGKDTERYGS 220
Cdd:cd03238 122 QQDINQLLEVIKGLIDL--GNTVILIEHN-LDVLSSADWIIDF--GPGSGKSGG 170
|
|
| ABCC_SUR2 |
cd03288 |
ATP-binding cassette domain 2 of the sulfonylurea receptor SUR; The SUR domain 2. The ... |
18-212 |
1.38e-05 |
|
ATP-binding cassette domain 2 of the sulfonylurea receptor SUR; The SUR domain 2. The sulfonylurea receptor SUR is an ATP binding cassette (ABC) protein of the ABCC/MRP family. Unlike other ABC proteins, it has no intrinsic transport function, neither active nor passive, but associates with the potassium channel proteins Kir6.1 or Kir6.2 to form the ATP-sensitive potassium (K(ATP)) channel. Within the channel complex, SUR serves as a regulatory subunit that fine-tunes the gating of Kir6.x in response to alterations in cellular metabolism. It constitutes a major pharmaceutical target as it binds numerous drugs, K(ATP) channel openers and blockers, capable of up- or down-regulating channel activity.
Pssm-ID: 213255 [Multi-domain] Cd Length: 257 Bit Score: 46.06 E-value: 1.38e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 18 PVIRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLSIGGKIMNDVP--AAQRGVAMVFQSYALFPHmtvfe 95
Cdd:cd03288 35 PVLKHVKAYIKPGQKVGICGRTGSGKSSLSLAFFRMVDIFDGKIVIDGIDISKLPlhTLRSRLSIILQDPILFSG----- 109
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 96 NMAFGLKLAKTPKeeiDRKVREAARVLQLEALLERRPKAL-----------SGGQRQRVAIGRAIVRQPGVFLFDEPLSN 164
Cdd:cd03288 110 SIRFNLDPECKCT---DDRLWEALEIAQLKNMVKSLPGGLdavvteggenfSVGQRQLFCLARAFVRKSSILIMDEATAS 186
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 928002514 165 LDATLRG--QTRIEIArlhkqFAKASVVYVTHdQIEAMTLADKIVLLHAG 212
Cdd:cd03288 187 IDMATENilQKVVMTA-----FADRTVVTIAH-RVSTILDADLVLVLSRG 230
|
|
| PLN03073 |
PLN03073 |
ABC transporter F family; Provisional |
4-166 |
1.49e-05 |
|
ABC transporter F family; Provisional
Pssm-ID: 215558 [Multi-domain] Cd Length: 718 Bit Score: 47.16 E-value: 1.49e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 4 ISLRGVQKAYGDGAPVIRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGdlsiggkimndvpaaqrgvaMVFQ 83
Cdd:PLN03073 509 ISFSDASFGYPGGPLLFKNLNFGIDLDSRIAMVGPNGIGKSTILKLISGELQPSSG--------------------TVFR 568
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 84 SYALfpHMTVF-ENMAFGLKLAKTPKEEIDR--------KVREAARVLQLEALLERRPK-ALSGGQRQRVAIGRAIVRQP 153
Cdd:PLN03073 569 SAKV--RMAVFsQHHVDGLDLSSNPLLYMMRcfpgvpeqKLRAHLGSFGVTGNLALQPMyTLSGGQKSRVAFAKITFKKP 646
|
170
....*....|...
gi 928002514 154 GVFLFDEPLSNLD 166
Cdd:PLN03073 647 HILLLDEPSNHLD 659
|
|
| PRK10938 |
PRK10938 |
putative molybdenum transport ATP-binding protein ModF; Provisional |
4-170 |
2.24e-05 |
|
putative molybdenum transport ATP-binding protein ModF; Provisional
Pssm-ID: 182852 [Multi-domain] Cd Length: 490 Bit Score: 46.16 E-value: 2.24e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 4 ISLRGVQKAYGDgAPVIRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGleDLTDG---DLSIGGKimndvpaaQRG--- 77
Cdd:PRK10938 261 IVLNNGVVSYND-RPILHNLSWQVNPGEHWQIVGPNGAGKSTLLSLITG--DHPQGysnDLTLFGR--------RRGsge 329
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 78 --------VAMVfqSYALfpHM-----TVFENM-------AFGLKLAKTPKEEIdrKVREAARVLQLEALLERRP-KALS 136
Cdd:PRK10938 330 tiwdikkhIGYV--SSSL--HLdyrvsTSVRNVilsgffdSIGIYQAVSDRQQK--LAQQWLDILGIDKRTADAPfHSLS 403
|
170 180 190
....*....|....*....|....*....|....
gi 928002514 137 GGQRQRVAIGRAIVRQPGVFLFDEPLSNLDATLR 170
Cdd:PRK10938 404 WGQQRLALIVRALVKHPTLLILDEPLQGLDPLNR 437
|
|
| tagH |
PRK13545 |
teichoic acids export protein ATP-binding subunit; Provisional |
20-224 |
3.16e-05 |
|
teichoic acids export protein ATP-binding subunit; Provisional
Pssm-ID: 184130 [Multi-domain] Cd Length: 549 Bit Score: 46.04 E-value: 3.16e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 20 IRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLSIGGKimndvpaaqrgVAMVFQSYALFPHMTVFENMAF 99
Cdd:PRK13545 40 LNNISFEVPEGEIVGIIGLNGSGKSTLSNLIAGVTMPNKGTVDIKGS-----------AALIAISSGLNGQLTGIENIEL 108
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 100 -GLKLAKTPKE--EIDRKVREAArvlQLEALLERRPKALSGGQRQRVAIGRAIVRQPGVFLFDEPLSNLDATLRGQTRIE 176
Cdd:PRK13545 109 kGLMMGLTKEKikEIIPEIIEFA---DIGKFIYQPVKTYSSGMKSRLGFAISVHINPDILVIDEALSVGDQTFTKKCLDK 185
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 928002514 177 IARLHKQfaKASVVYVTHDQIEAMTLADKIVLLHAGKDTErYGSIAQI 224
Cdd:PRK13545 186 MNEFKEQ--GKTIFFISHSLSQVKSFCTKALWLHYGQVKE-YGDIKEV 230
|
|
| araG |
PRK11288 |
L-arabinose ABC transporter ATP-binding protein AraG; |
16-213 |
4.22e-05 |
|
L-arabinose ABC transporter ATP-binding protein AraG;
Pssm-ID: 183077 [Multi-domain] Cd Length: 501 Bit Score: 45.29 E-value: 4.22e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 16 GAPVIRDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLSIGGK---IMNDVPAAQRGVAMV---FQSYALFP 89
Cdd:PRK11288 265 GPGLREPISFSVRAGEIVGLFGLVGAGRSELMKLLYGATRRTAGQVYLDGKpidIRSPRDAIRAGIMLCpedRKAEGIIP 344
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 90 HMTVFENMAFGLKLAKTPKEEI--DRKVREAARvLQLEALLERRPKA------LSGGQRQRVAIGRAIVRQPGVFLFDEP 161
Cdd:PRK11288 345 VHSVADNINISARRHHLRAGCLinNRWEAENAD-RFIRSLNIKTPSReqlimnLSGGNQQKAILGRWLSEDMKVILLDEP 423
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 928002514 162 LSNLDATLRGqtriEIARLHKQFAKA--SVVYVTHDQIEAMTLADKIVLLHAGK 213
Cdd:PRK11288 424 TRGIDVGAKH----EIYNVIYELAAQgvAVLFVSSDLPEVLGVADRIVVMREGR 473
|
|
| AAA |
smart00382 |
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ... |
30-208 |
4.55e-05 |
|
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.
Pssm-ID: 214640 [Multi-domain] Cd Length: 148 Bit Score: 43.13 E-value: 4.55e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 30 NEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLsiggkIMNDVPaaqrgvamvfqsyalfphmtvfenmafglklaktpke 109
Cdd:smart00382 2 GEVILIVGPPGSGKTTLARALARELGPPGGGV-----IYIDGE------------------------------------- 39
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 110 eidrKVREAARVLQLEALLERRPKALSGGQRQRVAIGRAIVRQPGVFLFDEPLSNLDATLRGQTRIEIARLH----KQFA 185
Cdd:smart00382 40 ----DILEEVLDQLLLIIVGGKKASGSGELRLRLALALARKLKPDVLILDEITSLLDAEQEALLLLLEELRLllllKSEK 115
|
170 180
....*....|....*....|...
gi 928002514 186 KASVVYVTHDQIEAMTLADKIVL 208
Cdd:smart00382 116 NLTVILTTNDEKDLGPALLRRRF 138
|
|
| MRP_assoc_pro |
TIGR00957 |
multi drug resistance-associated protein (MRP); This model describes multi drug ... |
19-230 |
9.30e-05 |
|
multi drug resistance-associated protein (MRP); This model describes multi drug resistance-associated protein (MRP) in eukaryotes. The multidrug resistance-associated protein is an integral membrane protein that causes multidrug resistance when overexpressed in mammalian cells. It belongs to ABC transporter superfamily. The protein topology and function was experimentally demonstrated by epitope tagging and immunofluorescence. Insertion of tags in the critical regions associated with drug efflux, abrogated its function. The C-terminal domain seem to highly conserved. [Transport and binding proteins, Other]
Pssm-ID: 188098 [Multi-domain] Cd Length: 1522 Bit Score: 44.55 E-value: 9.30e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 19 VIRDVDLEIGENEFCVFLGPSGCGKSTL-LCMIAGLEDlTDGDLSIGGkimndVPAAQRGVAMVFQSYALFPHMTVFenM 97
Cdd:TIGR00957 1301 VLRHINVTIHGGEKVGIVGRTGAGKSSLtLGLFRINES-AEGEIIIDG-----LNIAKIGLHDLRFKITIIPQDPVL--F 1372
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 98 AFGLKLAKTP-KEEIDRKVREAARVLQLEALLERRP-----------KALSGGQRQRVAIGRAIVRQPGVFLFDEPLSNL 165
Cdd:TIGR00957 1373 SGSLRMNLDPfSQYSDEEVWWALELAHLKTFVSALPdkldhecaeggENLSVGQRQLVCLARALLRKTKILVLDEATAAV 1452
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 928002514 166 DatLRGQTRIEiARLHKQFAKASVVYVTHDQIEAMTLADKIVLlhagkdteRYGSIAQIGAPLEL 230
Cdd:TIGR00957 1453 D--LETDNLIQ-STIRTQFEDCTVLTIAHRLNTIMDYTRVIVL--------DKGEVAEFGAPSNL 1506
|
|
| uvra |
TIGR00630 |
excinuclease ABC, A subunit; This family is a member of the ABC transporter superfamily of ... |
84-236 |
3.04e-04 |
|
excinuclease ABC, A subunit; This family is a member of the ABC transporter superfamily of proteins of which all members for which functions are known except the UvrA proteins are involved in the transport of material through membranes. UvrA orthologs are involved in the recognition of DNA damage as a step in nucleotide excision repair. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 273184 [Multi-domain] Cd Length: 925 Bit Score: 43.08 E-value: 3.04e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 84 SYALFPHMTVFENMAFGLKLAKTPK-----EEIDRKVREAARVLQ---LEAL-LERRPKALSGGQRQRVA----IGRAIV 150
Cdd:TIGR00630 429 SIADVSELSIREAHEFFNQLTLTPEekkiaEEVLKEIRERLGFLIdvgLDYLsLSRAAGTLSGGEAQRIRlatqIGSGLT 508
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 151 rqpGV-FLFDEPL--------SNLDATLRgqtrieiaRLHKQfaKASVVYVTHDQiEAMTLADKIVLLHAGKDtERYGSI 221
Cdd:TIGR00630 509 ---GVlYVLDEPSiglhqrdnRRLINTLK--------RLRDL--GNTLIVVEHDE-DTIRAADYVIDIGPGAG-EHGGEV 573
|
170
....*....|....*
gi 928002514 222 AQIGAPLELYHRPKS 236
Cdd:TIGR00630 574 VASGTPEEILANPDS 588
|
|
| PLN03073 |
PLN03073 |
ABC transporter F family; Provisional |
130-166 |
5.40e-04 |
|
ABC transporter F family; Provisional
Pssm-ID: 215558 [Multi-domain] Cd Length: 718 Bit Score: 42.15 E-value: 5.40e-04
10 20 30
....*....|....*....|....*....|....*..
gi 928002514 130 RRPKALSGGQRQRVAIGRAIVRQPGVFLFDEPLSNLD 166
Cdd:PLN03073 340 KATKTFSGGWRMRIALARALFIEPDLLLLDEPTNHLD 376
|
|
| 40850658_otr |
NF000106 |
oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit; |
130-213 |
6.09e-04 |
|
oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit;
Pssm-ID: 411078 [Multi-domain] Cd Length: 351 Bit Score: 41.64 E-value: 6.09e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 130 RRPKALSGGQRQRVAIGRAIVRQPGVFLFDEPLSNLDATLRGQTRIEIARLHKQfaKASVVYVTHDQIEAMTLADKIVLL 209
Cdd:NF000106 140 RAAAKYSGGMRRRLDLAASMIGRPAVLYLDEPTTGLDPRTRNEVWDEVRSMVRD--GATVLLTTQYMEEAEQLAHELTVI 217
|
....
gi 928002514 210 HAGK 213
Cdd:NF000106 218 DRGR 221
|
|
| PRK15439 |
PRK15439 |
autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional |
6-213 |
2.24e-03 |
|
autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional
Pssm-ID: 185336 [Multi-domain] Cd Length: 510 Bit Score: 40.03 E-value: 2.24e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 6 LRGVQKAYGDGAPVI----------RDVDLEIGENEFCVFLGPSGCGKSTLLCMIAGLEDLTDGDLSIGGKIMNDVPAAQ 75
Cdd:PRK15439 255 LPGNRRQQAAGAPVLtvedltgegfRNISLEVRAGEILGLAGVVGAGRTELAETLYGLRPARGGRIMLNGKEINALSTAQ 334
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 76 R-GVAMVF-----QSYALFPHMT--------VFENMAFGLKLAktpkeeidrkvREAARVLQLEALL-------ERRPKA 134
Cdd:PRK15439 335 RlARGLVYlpedrQSSGLYLDAPlawnvcalTHNRRGFWIKPA-----------RENAVLERYRRALnikfnhaEQAART 403
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 135 LSGGQRQRVAIGRAIVRQPGVFLFDEPLSNLDATlrgqTRIEIARLHKQFAK--ASVVYVTHDQIEAMTLADKIVLLHAG 212
Cdd:PRK15439 404 LSGGNQQKVLIAKCLEASPQLLIVDEPTRGVDVS----ARNDIYQLIRSIAAqnVAVLFISSDLEEIEQMADRVLVMHQG 479
|
.
gi 928002514 213 K 213
Cdd:PRK15439 480 E 480
|
|
| COG4637 |
COG4637 |
Predicted ATPase [General function prediction only]; |
20-47 |
5.29e-03 |
|
Predicted ATPase [General function prediction only];
Pssm-ID: 443675 [Multi-domain] Cd Length: 371 Bit Score: 38.76 E-value: 5.29e-03
10 20
....*....|....*....|....*...
gi 928002514 20 IRDVDLEIGEneFCVFLGPSGCGKSTLL 47
Cdd:COG4637 13 LRDLELPLGP--LTVLIGANGSGKSNLL 38
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| ABC_SMC3_euk |
cd03272 |
ATP-binding cassette domain of eukaryotic SMC3 proteins; The structural maintenance of ... |
130-206 |
6.35e-03 |
|
ATP-binding cassette domain of eukaryotic SMC3 proteins; The structural maintenance of chromosomes (SMC) proteins are large (approximately 110 to 170 kDa), and each is arranged into five recognizable domains. Amino-acid sequence homology of SMC proteins between species is largely confined to the amino- and carboxy-terminal globular domains. The amino-terminal domain contains a 'Walker A' nucleotide-binding domain (GxxGxGKS/T, in the single-letter amino-acid code), which by mutational studies has been shown to be essential in several proteins. The carboxy-terminal domain contains a sequence (the DA-box) that resembles a 'Walker B' motif, and a motif with homology to the signature sequence of the ATP-binding cassette (ABC) family of ATPases. The sequence homology within the carboxy-terminal domain is relatively high within the SMC1-SMC4 group, whereas SMC5 and SMC6 show some divergence in both of these sequences. In eukaryotic cells, the proteins are found as heterodimers of SMC1 paired with SMC3, SMC2 with SMC4, and SMC5 with SMC6 (formerly known as Rad18).
Pssm-ID: 213239 [Multi-domain] Cd Length: 243 Bit Score: 38.01 E-value: 6.35e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 928002514 130 RRPKALSGGQRQRVAIGR--AIVR-QPGVF-LFDEPLSNLDAtlrgQTRIEIARLHKQFAKASVVYVTHDQIEAMTLADK 205
Cdd:cd03272 154 QEMQQLSGGQKSLVALALifAIQKcDPAPFyLFDEIDAALDA----QYRTAVANMIKELSDGAQFITTTFRPELLEVADK 229
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gi 928002514 206 I 206
Cdd:cd03272 230 F 230
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| YjeQ_EngC |
cd01854 |
Ribosomal interacting GTPase YjeQ/EngC, a circularly permuted subfamily of the Ras GTPases; ... |
33-62 |
7.12e-03 |
|
Ribosomal interacting GTPase YjeQ/EngC, a circularly permuted subfamily of the Ras GTPases; YjeQ (YloQ in Bacillus subtilis) is a ribosomal small subunit-dependent GTPase; hence also known as RsgA. YjeQ is a late-stage ribosomal biogenesis factor involved in the 30S subunit maturation, and it represents a protein family whose members are broadly conserved in bacteria and have been shown to be essential to the growth of E. coli and B. subtilis. Proteins of the YjeQ family contain all sequence motifs typical of the vast class of P-loop-containing GTPases, but show a circular permutation, with a G4-G1-G3 pattern of motifs as opposed to the regular G1-G3-G4 pattern seen in most GTPases. All YjeQ family proteins display a unique domain architecture, which includes an N-terminal OB-fold RNA-binding domain, the central permuted GTPase domain, and a zinc knuckle-like C-terminal cysteine domain.
Pssm-ID: 206747 [Multi-domain] Cd Length: 211 Bit Score: 37.38 E-value: 7.12e-03
10 20 30
....*....|....*....|....*....|
gi 928002514 33 CVFLGPSGCGKSTLLCMIAGLEDLTDGDLS 62
Cdd:cd01854 88 SVLVGQSGVGKSTLLNALLPELVLATGEIS 117
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|
| CysA_C_terminal |
pfam17850 |
CysA C-terminal regulatory domain; ABC (ATP-binding cassette) transporters share a common ... |
249-299 |
7.27e-03 |
|
CysA C-terminal regulatory domain; ABC (ATP-binding cassette) transporters share a common architecture comprising two variable hydrophobic transmembrane domains (TMDs) that form the translocation pathway and two conserved hydrophilic ABC-ATPases that hydrolyze ATP. This is the C-terminal regulatory domain found at the ATPase subunit of CysA, a putative sulfate ABC transporter from Alicyclobacillus acidocaldarius. The regulatory domain of CysA is built up of an elongated beta-barrel composed of two beta-sandwiches that form a common hydrophobic core.
Pssm-ID: 465531 [Multi-domain] Cd Length: 43 Bit Score: 33.96 E-value: 7.27e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|.
gi 928002514 249 NFLPGRVAsvdaQGVIvtldtTLENVRVPVDGAALEVAQPVTLGVRPEHLE 299
Cdd:pfam17850 1 NLFHGRVE----DGRV-----RIGGLALPLPELAGAEGSEVVAYVRPHDLE 42
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|
| uvra |
TIGR00630 |
excinuclease ABC, A subunit; This family is a member of the ABC transporter superfamily of ... |
20-46 |
8.49e-03 |
|
excinuclease ABC, A subunit; This family is a member of the ABC transporter superfamily of proteins of which all members for which functions are known except the UvrA proteins are involved in the transport of material through membranes. UvrA orthologs are involved in the recognition of DNA damage as a step in nucleotide excision repair. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 273184 [Multi-domain] Cd Length: 925 Bit Score: 38.46 E-value: 8.49e-03
10 20
....*....|....*....|....*..
gi 928002514 20 IRDVDLEIGENEFCVFLGPSGCGKSTL 46
Cdd:TIGR00630 12 LKNIDVEIPRDKLVVITGLSGSGKSSL 38
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