NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|927372421|ref|YP_009164703|]
View 

NADH dehydrogenase subunit 6 (mitochondrion) [Nestor notabilis]

Protein Classification

NADH dehydrogenase subunit 6( domain architecture ID 10009582)

NADH dehydrogenase subunit 6 (mitochondrion) is the core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that functions in the transfer of electrons from NADH to the respiratory chain

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
ND6 MTH00138
NADH dehydrogenase subunit 6; Provisional
 1-171 2.31e-53

NADH dehydrogenase subunit 6; Provisional


:

Pssm-ID: 177196  Cd Length: 173  Bit Score: 167.24  E-value: 2.31e-53
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 927372421   1 MTYFVLFLGVGFVLGSLGVASNPSPYYGVIGLVVGAVVGCGWLVSLGLSFVSLALFMVYLGGMLVVFVYSVSLAADPFPQ 80
Cdd:MTH00138   1 MTYLMSLFLLGLVLGLVAVASNPSPYFAALGLVVVAGVGCGVLVGHGGSFLSLVLFLIYLGGMLVVFAYSAALAAEPYPE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 927372421  81 AWGDRRVVGYIVGLVLVVVLGFILGGLG-VKFGVDVVDSVGACF-IRLDFSGVALFYSSGVGMFLVAGWGLLLTLFVVLE 158
Cdd:MTH00138  81 SWGSWSVLGYVVGYLVGVVLAAGLFWGGwYEGSWVVVDELKEFSvLRGDVGGVALMYSSGGGMLVICAWVLLLTLFVVLE 160

                        170
                 ....*....|...
gi 927372421 159 LVRGLSRGAIRAV 171
Cdd:MTH00138 161 LTRGLSRGALRAV 173
 
Name Accession Description Interval E-value
ND6 MTH00138
NADH dehydrogenase subunit 6; Provisional
 1-171 2.31e-53

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 177196  Cd Length: 173  Bit Score: 167.24  E-value: 2.31e-53
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 927372421   1 MTYFVLFLGVGFVLGSLGVASNPSPYYGVIGLVVGAVVGCGWLVSLGLSFVSLALFMVYLGGMLVVFVYSVSLAADPFPQ 80
Cdd:MTH00138   1 MTYLMSLFLLGLVLGLVAVASNPSPYFAALGLVVVAGVGCGVLVGHGGSFLSLVLFLIYLGGMLVVFAYSAALAAEPYPE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 927372421  81 AWGDRRVVGYIVGLVLVVVLGFILGGLG-VKFGVDVVDSVGACF-IRLDFSGVALFYSSGVGMFLVAGWGLLLTLFVVLE 158
Cdd:MTH00138  81 SWGSWSVLGYVVGYLVGVVLAAGLFWGGwYEGSWVVVDELKEFSvLRGDVGGVALMYSSGGGMLVICAWVLLLTLFVVLE 160

                        170
                 ....*....|...
gi 927372421 159 LVRGLSRGAIRAV 171
Cdd:MTH00138 161 LTRGLSRGALRAV 173
Oxidored_q3 pfam00499
NADH-ubiquinone/plastoquinone oxidoreductase chain 6;
17-159 1.47e-09

NADH-ubiquinone/plastoquinone oxidoreductase chain 6;


Pssm-ID: 459832 [Multi-domain]  Cd Length: 141  Bit Score: 53.28  E-value: 1.47e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 927372421   17 LGVASNPSPYYGVIGLVVGAVVGCGWLVSLGLSFVSLALFMVYLGGMLVVFVYSVSLAADPFPQAWGdRRVVGYIVGLVL 96
Cdd:pfam00499   1 LGVVTSRNPVHSALFLVLTFFGVAGLYLLLGAEFLAAVQVLVYVGAIMVLFLFVIMLLLAEEEPEKL-RSGLPLAALLLG 79

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 927372421   97 VVVLGFILGGLGVKFGVDVVDSVGACFIRLDFSGVALFYsSGVGMFLVAGWGLLLTLFVVLEL 159
Cdd:pfam00499  80 LLLLALLLLVLLSASLTPAAAAAAPDVGNIEAIGELLFT-DYLLPFELASVLLLVALVGAIVL 141
 
Name Accession Description Interval E-value
ND6 MTH00138
NADH dehydrogenase subunit 6; Provisional
 1-171 2.31e-53

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 177196  Cd Length: 173  Bit Score: 167.24  E-value: 2.31e-53
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 927372421   1 MTYFVLFLGVGFVLGSLGVASNPSPYYGVIGLVVGAVVGCGWLVSLGLSFVSLALFMVYLGGMLVVFVYSVSLAADPFPQ 80
Cdd:MTH00138   1 MTYLMSLFLLGLVLGLVAVASNPSPYFAALGLVVVAGVGCGVLVGHGGSFLSLVLFLIYLGGMLVVFAYSAALAAEPYPE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 927372421  81 AWGDRRVVGYIVGLVLVVVLGFILGGLG-VKFGVDVVDSVGACF-IRLDFSGVALFYSSGVGMFLVAGWGLLLTLFVVLE 158
Cdd:MTH00138  81 SWGSWSVLGYVVGYLVGVVLAAGLFWGGwYEGSWVVVDELKEFSvLRGDVGGVALMYSSGGGMLVICAWVLLLTLFVVLE 160

                        170
                 ....*....|...
gi 927372421 159 LVRGLSRGAIRAV 171
Cdd:MTH00138 161 LTRGLSRGALRAV 173
ND6 MTH00115
NADH dehydrogenase subunit 6; Provisional
 1-171 8.19e-51

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214424  Cd Length: 174  Bit Score: 160.68  E-value: 8.19e-51
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 927372421   1 MTYFVLFLGVGFVLGSLGVASNPSPYYGVIGLVVGAVVGCGWLVSLGLSFVSLALFMVYLGGMLVVFVYSVSLAADPFPQ 80
Cdd:MTH00115   1 MMYFVFLLGVCFVLGVVGVASNPSPYYGVVSLVLASVFGCGVLVSLGGSFVSLVLFLVYLGGMLVVFAYSVSLAADPYPE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 927372421  81 AWGDRRVVGYIVGLVLVVVLGFILGGLGV---KFGVDVVDSVGACFIRLDFSGVALFYSSGVGMFLVAGWGLLLTLFVVL 157
Cdd:MTH00115  81 AWGDWGVVGYVVGFVLVVVVVGVVVGGLWgmeGVGVVTVDSGGLFVVRLDFSGVSLFYSSGGGGLLVCGWGLLLTLFVVL 160

                        170
                 ....*....|....
gi 927372421 158 ELVRGLSRGAIRAV 171
Cdd:MTH00115 161 ELVRGLSRGALRAF 174
ND6 MTH00065
NADH dehydrogenase subunit 6; Provisional
 1-171 4.84e-49

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214415  Cd Length: 172  Bit Score: 156.16  E-value: 4.84e-49
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 927372421   1 MTYFVLFLGVGFVLGSLGVASNPSPYYGVIGLVVGAVVGCGWLVSLGLSFVSLALFMVYLGGMLVVFVYSVSLAADPFPQ 80
Cdd:MTH00065   1 MMYLGFLGMLGLVVGLVAVASNPSPYFAALGLVLGAVCGCLVLVELGVSFLSLVLFLIYLGGMLVVFAYSAALAAEPYPE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 927372421  81 AWGDRRVVGYIVGLVLVVVLGFIL-GGLGVKFGVDVVDSVGACFIRLDFSGVALFYSSGVGMFLVAGWGLLLTLFVVLEL 159
Cdd:MTH00065  81 AWGSWSVLVYVLFYLLLLIVGYILfGCNFSLEFLFTNYDTEFSVVGYDWGGVGLMYSSGGWFLMISGWVLLLTLFVVLEV 160

                        170
                 ....*....|..
gi 927372421 160 VRGLSRGAIRAV 171
Cdd:MTH00065 161 TRGLSRGSLRAV 172
ND6 MTH00109
NADH dehydrogenase subunit 6; Provisional
 1-162 3.82e-28

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214421  Cd Length: 175  Bit Score: 102.96  E-value: 3.82e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 927372421   1 MTYFVLFLGVGFVLGSLGVASNPSPYYGVIGLVVGAVVGCGWLVSLGLSFVSLALFMVYLGGMLVVFVYSVSLAADPFPQ 80
Cdd:MTH00109   2 MMYIVFILSVLFVLGFVGFSSKPSPIYGGLGLIVSGGVGCGIVLSFGGSFLGLMVFLIYLGGMLVVFGYTTAMATEEYPE 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 927372421  81 AWGDRRVV---GYIVGLVLVVVLGFILGGLGVKFGVD--------VVDSVGACFIRLDFSGVALFYSSGVGMFLVAGWGL 149
Cdd:MTH00109  82 TWVSNKVVlgaLLLGLLMELLLVLYVLKDDEVEVVFNfnglgdwvIYDTGGSGFFSEDAMGVAALYSYGTWLVVVTGWSL 161

                        170
                 ....*....|...
gi 927372421 150 LLTLFVVLELVRG 162
Cdd:MTH00109 162 FIGVFVIIEITRG 174
ND6 MTH00214
NADH dehydrogenase subunit 6; Provisional
 1-171 7.21e-24

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214461  Cd Length: 168  Bit Score: 91.59  E-value: 7.21e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 927372421   1 MTYFVLFLGVGFVLGSLGVASNPSPYYGVIGLVVGAVVGCGWLVSLGLSFVSLALFMVYLGGMLVVFVYSVSLAADPFPQ 80
Cdd:MTH00214   1 MLYFVFLLMFGFLLGLMMVASSPSPYFGALGLVLLALLGCFLLLSHGNSFLGLILFLIYLGGMLVVFSYSAALAADPYPE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 927372421  81 AWGDRRVVGYIVGLVLVVVLGFILGGLGVKFGVDVVDSVgacFIRLDFSGVALFYSSGVGMFLVAGWGLLLTLFVVLELV 160
Cdd:MTH00214  81 SWGGWSVLLFFLFYLLGLGFVGFYFYGGWEMLSWMGVDE---ANNLDLSGVSDLYSRGFFLLLLGGVVLFLVLFVVLELV 157

                        170
                 ....*....|.
gi 927372421 161 RGLSRGAIRAV 171
Cdd:MTH00214 158 RGLSRGALRVV 168
ND6 MTH00045
NADH dehydrogenase subunit 6; Validated
 13-170 2.07e-13

NADH dehydrogenase subunit 6; Validated


Pssm-ID: 177120  Cd Length: 162  Bit Score: 64.16  E-value: 2.07e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 927372421  13 VLGSLGVASNPSPYYGVIGLVVGAVVGCGWLVSLGLSFVSLALFMVYLGGMLVVFVYSVSLAADPFPqawgdrrVVGYIV 92
Cdd:MTH00045  11 LFGSTLVFYSLSPYYSALGLVLVSLSGCLLLSLLGLSFLALLLLLIYMGGMLVVFVYSSALSAERYP-------SVSNLG 83

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 927372421  93 GLVLVVVLGFILGGLGVKFGVDVVDSVGACFIRLDFSGVALFYSSGVGMFLVAGWGLLLTLFVVLELVRGLSRGAIRA 170
Cdd:MTH00045  84 EVLVLSLLLSLWVFISFDNFLELSNNNWSLVSLSDLVGSSELYNSGGLYLLLGGFILLVALVVALVISFGHEYSSLRA 161
Oxidored_q3 pfam00499
NADH-ubiquinone/plastoquinone oxidoreductase chain 6;
17-159 1.47e-09

NADH-ubiquinone/plastoquinone oxidoreductase chain 6;


Pssm-ID: 459832 [Multi-domain]  Cd Length: 141  Bit Score: 53.28  E-value: 1.47e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 927372421   17 LGVASNPSPYYGVIGLVVGAVVGCGWLVSLGLSFVSLALFMVYLGGMLVVFVYSVSLAADPFPQAWGdRRVVGYIVGLVL 96
Cdd:pfam00499   1 LGVVTSRNPVHSALFLVLTFFGVAGLYLLLGAEFLAAVQVLVYVGAIMVLFLFVIMLLLAEEEPEKL-RSGLPLAALLLG 79

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 927372421   97 VVVLGFILGGLGVKFGVDVVDSVGACFIRLDFSGVALFYsSGVGMFLVAGWGLLLTLFVVLEL 159
Cdd:pfam00499  80 LLLLALLLLVLLSASLTPAAAAAAPDVGNIEAIGELLFT-DYLLPFELASVLLLVALVGAIVL 141
ND6 MTH00021
NADH dehydrogenase subunit 6; Validated
 7-84 2.72e-03

NADH dehydrogenase subunit 6; Validated


Pssm-ID: 214401 [Multi-domain]  Cd Length: 188  Bit Score: 36.63  E-value: 2.72e-03
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 927372421   7 FLGVGFVLGSLGVASNPSPYYGVIGLVVGAVVGCGWLVSLGLSFVSLALFMVYLGGMLVVFVYSVSLAADP-FPQAWGD 84
Cdd:MTH00021   1 FFSLGIIGSGIMVISALNPVHSIFWLVVVFVNSAVFFILLGLDFLALMFLIIYVGAIAILFLFVIMLLNLTdFPPAFGG 79
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH