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Conserved domains on  [gi|924601414|ref|WP_053523847|]
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DNA polymerase III subunit gamma/tau [Burkholderia cenocepacia]

Protein Classification

DNA polymerase III subunit gamma/tau( domain architecture ID 11482527)

DNA polymerase III subunit gamma/tau is part of the DNA polymerase III holoenzyme; gamma and tau subunits are isoforms and either one or both may be present in the holoenzyme; gamma interacts with the delta subunit to transfer the beta subunit on the DNA while tau serves as a scaffold to help in the dimerization of the core complex

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
PRK07003 PRK07003
DNA polymerase III subunit gamma/tau;
1-792 0e+00

DNA polymerase III subunit gamma/tau;


:

Pssm-ID: 235906 [Multi-domain]  Cd Length: 830  Bit Score: 1243.58  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414   1 MTYQVLARKWRPKDFASLVGQEHVVRALTHALDGGRLHHAYLFTGTRGVGKTTLSRIFAKALNCETGVTSQPCGVCRACR 80
Cdd:PRK07003   1 MTYQVLARKWRPKDFASLVGQEHVVRALTHALDGGRLHHAYLFTGTRGVGKTTLSRIFAKALNCETGVTSQPCGVCRACR 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414  81 EIDEGRFVDYVEMDAASNRGVDEMAALLERAVYAPVDARFKVYMIDEVHMLTNHAFNAMLKTLEEPPPHVKFILATTDPQ 160
Cdd:PRK07003  81 EIDEGRFVDYVEMDAASNRGVDEMAALLERAVYAPVDARFKVYMIDEVHMLTNHAFNAMLKTLEEPPPHVKFILATTDPQ 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414 161 KIPVTVLSRCLQFNLKQMPAGHIVSHLERILGEEQITFEPQALRLLARAAQGSMRDALSLTDQAIAYSANEVTESAVSGM 240
Cdd:PRK07003 161 KIPVTVLSRCLQFNLKQMPAGHIVSHLERILGEERIAFEPQALRLLARAAQGSMRDALSLTDQAIAYSANEVTETAVSGM 240
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414 241 LGALDQTYMVRLLDALAAANGPEILAIADEMSLRSLSFSTALQDLASLLHRIAWAQFAPGSVLDEWPEAADLRRFAETLS 320
Cdd:PRK07003 241 LGALDQTYMVRLLDALAAGDGPEILAVADEMALRSLSFSTALQDLASLLHRIAWAQFAPASVLDEWPEAADLRRFAELLS 320
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414 321 PEQVQLFYQIATVGRAELGLAPDEYAGFTMTLLRMLAFEPAVGAGSAPGGQPSVPPR------AVPAPRAAAAPTAAAAK 394
Cdd:PRK07003 321 PEQVQLFYQIATVGRGELGLAPDEYAGFTMTLLRMLAFEPAVTGGGAPGGGVPARVAgavpapGARAAAAVGASAVPAVT 400
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414 395 PVSATPAGAA---RPQAAAPAAPAAPVARSAPAQSSDEAERPAAKPPAVQSPAEAAAPIPAAADAQAIELP-QPETKAAP 470
Cdd:PRK07003 401 AVTGAAGAALapkAAAAAAATRAEAPPAAPAPPATADRGDDAADGDAPVPAKANARASADSRCDERDAQPPaDSGSASAP 480
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414 471 AGDMPPPTRKEPEPPAV----------------AAVQRNDEPAPQAEPAPRAASPEPAAVRPAARAGGAAAALDVLRNAG 534
Cdd:PRK07003 481 ASDAPPDAAFEPAPRAAapsaatpaavpdarapAAASREDAPAAAAPPAPEARPPTPAAAAPAARAGGAAAALDVLRNAG 560
                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414 535 MRVSSDRGGRAGATAKPAAAQPAAEKPAAPRPAVQVPTPRAAARAPQAA-----------ESRQPSPPWEDIPPDDYVPL 603
Cdd:PRK07003 561 MRVSSDRGARAAAAAKPAAAPAAAPKPAAPRVAVQVPTPRARAATGDAPpngaaraeqaaESRGAPPPWEDIPPDDYVPL 640
                        650       660       670       680       690       700       710       720
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414 604 SADEMFGGSDDSFVPVFDSGPDDVRVTPKPAEtRPAAPIDTRPLPPAIALDPIGFDGEWPALAARLPLKGVAYQLAFNSE 683
Cdd:PRK07003 641 SADEGFGGPDDGFVPVFDSGPDDVRVAPKPAD-APAPPVDTRPLPPAIPLDAIGFDGEWPALAARLPLKGVAYQLAFNSE 719
                        730       740       750       760       770       780       790       800
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414 684 LTAVDASTLKLSVPVPQYADAAQVTKLKAALADALGKPVEVSVEVGPARRTAAALDAAARAARQREAEQEIHGDPFVQQL 763
Cdd:PRK07003 720 LTAADGGTLKLAVPVPQYADAAQVAKLKAALADALGKPVEVAVEVGPARRTAAALDAAERAKRQREAEQEIHADPFVQQL 799
                        810       820       830
                 ....*....|....*....|....*....|.
gi 924601414 764 VRDFGARIVEGSVRPLA--DSAPDGVPPTLH 792
Cdd:PRK07003 800 LREFGASIVEGSIRPVAaeAGAPDGASPTLH 830
 
Name Accession Description Interval E-value
PRK07003 PRK07003
DNA polymerase III subunit gamma/tau;
1-792 0e+00

DNA polymerase III subunit gamma/tau;


Pssm-ID: 235906 [Multi-domain]  Cd Length: 830  Bit Score: 1243.58  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414   1 MTYQVLARKWRPKDFASLVGQEHVVRALTHALDGGRLHHAYLFTGTRGVGKTTLSRIFAKALNCETGVTSQPCGVCRACR 80
Cdd:PRK07003   1 MTYQVLARKWRPKDFASLVGQEHVVRALTHALDGGRLHHAYLFTGTRGVGKTTLSRIFAKALNCETGVTSQPCGVCRACR 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414  81 EIDEGRFVDYVEMDAASNRGVDEMAALLERAVYAPVDARFKVYMIDEVHMLTNHAFNAMLKTLEEPPPHVKFILATTDPQ 160
Cdd:PRK07003  81 EIDEGRFVDYVEMDAASNRGVDEMAALLERAVYAPVDARFKVYMIDEVHMLTNHAFNAMLKTLEEPPPHVKFILATTDPQ 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414 161 KIPVTVLSRCLQFNLKQMPAGHIVSHLERILGEEQITFEPQALRLLARAAQGSMRDALSLTDQAIAYSANEVTESAVSGM 240
Cdd:PRK07003 161 KIPVTVLSRCLQFNLKQMPAGHIVSHLERILGEERIAFEPQALRLLARAAQGSMRDALSLTDQAIAYSANEVTETAVSGM 240
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414 241 LGALDQTYMVRLLDALAAANGPEILAIADEMSLRSLSFSTALQDLASLLHRIAWAQFAPGSVLDEWPEAADLRRFAETLS 320
Cdd:PRK07003 241 LGALDQTYMVRLLDALAAGDGPEILAVADEMALRSLSFSTALQDLASLLHRIAWAQFAPASVLDEWPEAADLRRFAELLS 320
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414 321 PEQVQLFYQIATVGRAELGLAPDEYAGFTMTLLRMLAFEPAVGAGSAPGGQPSVPPR------AVPAPRAAAAPTAAAAK 394
Cdd:PRK07003 321 PEQVQLFYQIATVGRGELGLAPDEYAGFTMTLLRMLAFEPAVTGGGAPGGGVPARVAgavpapGARAAAAVGASAVPAVT 400
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414 395 PVSATPAGAA---RPQAAAPAAPAAPVARSAPAQSSDEAERPAAKPPAVQSPAEAAAPIPAAADAQAIELP-QPETKAAP 470
Cdd:PRK07003 401 AVTGAAGAALapkAAAAAAATRAEAPPAAPAPPATADRGDDAADGDAPVPAKANARASADSRCDERDAQPPaDSGSASAP 480
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414 471 AGDMPPPTRKEPEPPAV----------------AAVQRNDEPAPQAEPAPRAASPEPAAVRPAARAGGAAAALDVLRNAG 534
Cdd:PRK07003 481 ASDAPPDAAFEPAPRAAapsaatpaavpdarapAAASREDAPAAAAPPAPEARPPTPAAAAPAARAGGAAAALDVLRNAG 560
                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414 535 MRVSSDRGGRAGATAKPAAAQPAAEKPAAPRPAVQVPTPRAAARAPQAA-----------ESRQPSPPWEDIPPDDYVPL 603
Cdd:PRK07003 561 MRVSSDRGARAAAAAKPAAAPAAAPKPAAPRVAVQVPTPRARAATGDAPpngaaraeqaaESRGAPPPWEDIPPDDYVPL 640
                        650       660       670       680       690       700       710       720
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414 604 SADEMFGGSDDSFVPVFDSGPDDVRVTPKPAEtRPAAPIDTRPLPPAIALDPIGFDGEWPALAARLPLKGVAYQLAFNSE 683
Cdd:PRK07003 641 SADEGFGGPDDGFVPVFDSGPDDVRVAPKPAD-APAPPVDTRPLPPAIPLDAIGFDGEWPALAARLPLKGVAYQLAFNSE 719
                        730       740       750       760       770       780       790       800
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414 684 LTAVDASTLKLSVPVPQYADAAQVTKLKAALADALGKPVEVSVEVGPARRTAAALDAAARAARQREAEQEIHGDPFVQQL 763
Cdd:PRK07003 720 LTAADGGTLKLAVPVPQYADAAQVAKLKAALADALGKPVEVAVEVGPARRTAAALDAAERAKRQREAEQEIHADPFVQQL 799
                        810       820       830
                 ....*....|....*....|....*....|.
gi 924601414 764 VRDFGARIVEGSVRPLA--DSAPDGVPPTLH 792
Cdd:PRK07003 800 LREFGASIVEGSIRPVAaeAGAPDGASPTLH 830
DnaX COG2812
DNA polymerase III, gamma/tau subunits [Replication, recombination and repair];
1-357 2.78e-167

DNA polymerase III, gamma/tau subunits [Replication, recombination and repair];


Pssm-ID: 442061 [Multi-domain]  Cd Length: 340  Bit Score: 486.24  E-value: 2.78e-167
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414   1 MTYQVlarkwrPKDFASLVGQEHVVRALTHALDGGRLHHAYLFTGTRGVGKTTLSRIFAKALNCETGVTSQPCGVCRACR 80
Cdd:COG2812    1 MSYQV------PQTFDDVVGQEHVVRTLKNALASGRLAHAYLFTGPRGVGKTTLARILAKALNCENGPTGEPCGECESCR 74
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414  81 EIDEGRFVDYVEMDA-ASNRGVDEMAALLERAVYAPVDARFKVYMIDEVHMLTNHAFNAMLKTLEEPPPHVKFILATTDP 159
Cdd:COG2812   75 AIAAGSHPDVIEIDAeASNIGVDDIRELIEKVSYAPVEGRYKVYIIDEAHMLTTEAFNALLKTLEEPPPHVVFILATTEP 154
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414 160 QKIPVTVLSRCLQFNLKQMPAGHIVSHLERILGEEQITFEPQALRLLARAAQGSMRDALSLTDQAIAYsanevtesavsg 239
Cdd:COG2812  155 QKLLPTILSRCQRFDFRRLPPEEIAEHLAKIAEREGIEIEPEALALIARAADGSMRDALSLLDQAIAF------------ 222
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414 240 mlGALD-QTYMVRLLDALAAANGPEILAIADEMSLRSLSFSTALQDLASLLHRIAWAQFAPGS-VLDEWPEAADLRRFAE 317
Cdd:COG2812  223 --GLLDrRELLLDLLEALLAGDVAALLALAEELAKRGRDLKRFLDDLLSLLRDLLLLKLGPDAeLLVNEDERERLQELAR 300
                        330       340       350       360
                 ....*....|....*....|....*....|....*....|
gi 924601414 318 TLSPEQVQLFYQIATVGRAELGLAPDEYAGFTMTLLRMLA 357
Cdd:COG2812  301 RLSPERLLRAIQILLEARRELERNVNPRLALEMLLLRLAR 340
dnaX_nterm TIGR02397
DNA polymerase III, subunit gamma and tau; This model represents the well-conserved first ~ ...
3-356 1.48e-166

DNA polymerase III, subunit gamma and tau; This model represents the well-conserved first ~ 365 amino acids of the translation of the dnaX gene. The full-length product of the dnaX gene in the model bacterium E. coli is the DNA polymerase III tau subunit. A translational frameshift leads to early termination and a truncated protein subunit gamma, about 1/3 shorter than tau and present in roughly equal amounts. This frameshift mechanism is not necessarily universal for species with DNA polymerase III but appears conserved in the exterme thermophile Thermus thermophilis. [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 274111 [Multi-domain]  Cd Length: 355  Bit Score: 485.15  E-value: 1.48e-166
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414    3 YQVLARKWRPKDFASLVGQEHVVRALTHALDGGRLHHAYLFTGTRGVGKTTLSRIFAKALNCETGVTSQPCGVCRACREI 82
Cdd:TIGR02397   1 YQVLARKYRPQTFEDVIGQEHIVQTLKNAIKNGRIAHAYLFSGPRGTGKTSIARIFAKALNCQNGPDGEPCNECESCKEI 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414   83 DEGRFVDYVEMDAASNRGVDEMAALLERAVYAPVDARFKVYMIDEVHMLTNHAFNAMLKTLEEPPPHVKFILATTDPQKI 162
Cdd:TIGR02397  81 NSGSSLDVIEIDAASNNGVDDIREILDNVKYAPSSGKYKVYIIDEVHMLSKSAFNALLKTLEEPPEHVVFILATTEPHKI 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414  163 PVTVLSRCLQFNLKQMPAGHIVSHLERILGEEQITFEPQALRLLARAAQGSMRDALSLTDQAIAYSANEVTESAVSGMLG 242
Cdd:TIGR02397 161 PATILSRCQRFDFKRIPLEDIVERLKKILDKEGIKIEDEALELIARAADGSLRDALSLLDQLISFGNGKITYEDVNELLG 240
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414  243 ALDQTYMVRLLDALAAANGPEILAIADEMSLRSLSFSTALQDLASLLHRIAWAQFAPGSVL-DEWPEAADLRRFAETLSP 321
Cdd:TIGR02397 241 LVDDEKLIELLEAILNKDTAEALKILDEILESGVDPEKFLEDLIEILRDLLLIKKTPSNLLaVLESEQEFLKELALKLSL 320
                         330       340       350
                  ....*....|....*....|....*....|....*
gi 924601414  322 EQVQLFYQIATVGRAELGLAPDEYAGFTMTLLRML 356
Cdd:TIGR02397 321 EFLLRLLDILLEALKDLRFSNDPRIWLEMTLLRLL 355
DNA_pol3_delta2 pfam13177
DNA polymerase III, delta subunit; DNA polymerase III, delta subunit (EC 2.7.7.7) is required ...
20-179 8.01e-46

DNA polymerase III, delta subunit; DNA polymerase III, delta subunit (EC 2.7.7.7) is required for, along with delta' subunit, the assembly of the processivity factor beta(2) onto primed DNA in the DNA polymerase III holoenzyme-catalyzed reaction. The delta subunit is also known as HolA.


Pssm-ID: 433013 [Multi-domain]  Cd Length: 161  Bit Score: 161.22  E-value: 8.01e-46
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414   20 GQEHVVRALTHALDGGRLHHAYLFTGTRGVGKTTLSRIFAKALNCETGVTSQPCGVCRACREIDEGRFVD--YVEMDAAS 97
Cdd:pfam13177   1 GQPEAIQLLQNSLENGRLSHAYLFSGPEGVGKLELALAFAKALFCEEPGDDLPCGQCRSCRRIESGNHPDlvIIEPEGQS 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414   98 NRgVDEMAALLERAVYAPVDARFKVYMIDEVHMLTNHAFNAMLKTLEEPPPHVKFILATTDPQKIPVTVLSRCLQFNLKQ 177
Cdd:pfam13177  81 IK-IDQIRELQKEFSKSPYEGKKKVYIIEDAEKMTASAANSLLKFLEEPPGNTVIILLTENPSRLLPTIRSRCQIIRFKP 159

                  ..
gi 924601414  178 MP 179
Cdd:pfam13177 160 LS 161
HLD_clamp_pol_III_gamma_tau cd18137
helical lid domain of DNA polymerase III subunits gamma and tau; DNA polymerase III subunit ...
178-242 1.16e-24

helical lid domain of DNA polymerase III subunits gamma and tau; DNA polymerase III subunit gamma/tau is part of the DNA polymerase III holoenzyme. Gamma and tau subunits are isoforms, both containing the helical lid domain. Gamma interacts with the delta subunit to transfer the beta subunit on the DNA while tau serves as a scaffold to help in the dimerization of the core complex. Both are members of the clamp-loader clade of the AAA+ superfamily.


Pssm-ID: 350839 [Multi-domain]  Cd Length: 65  Bit Score: 97.58  E-value: 1.16e-24
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 924601414 178 MPAGHIVSHLERILGEEQITFEPQALRLLARAAQGSMRDALSLTDQAIAYSANEVTESAVSGMLG 242
Cdd:cd18137    1 ISVEDIVGRLAHILEKEGIEIEDEALELIARAAEGSMRDALSLLDQAIAFGGGRVTLDDVREMLG 65
AAA smart00382
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ...
38-162 2.61e-07

ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.


Pssm-ID: 214640 [Multi-domain]  Cd Length: 148  Bit Score: 50.83  E-value: 2.61e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414    38 HHAYLFTGTRGVGKTTLSRIFAKALNCETGvtsqpcGVCRAC-----REIDEGRFVDYVEMDAASNRGVDEMAALLERAV 112
Cdd:smart00382   2 GEVILIVGPPGSGKTTLARALARELGPPGG------GVIYIDgedilEEVLDQLLLIIVGGKKASGSGELRLRLALALAR 75
                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 924601414   113 YAPVDarfkVYMIDEVHMLTNHAFNAML--------KTLEEPPPHVKFILATTDPQKI 162
Cdd:smart00382  76 KLKPD----VLILDEITSLLDAEQEALLllleelrlLLLLKSEKNLTVILTTNDEKDL 129
 
Name Accession Description Interval E-value
PRK07003 PRK07003
DNA polymerase III subunit gamma/tau;
1-792 0e+00

DNA polymerase III subunit gamma/tau;


Pssm-ID: 235906 [Multi-domain]  Cd Length: 830  Bit Score: 1243.58  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414   1 MTYQVLARKWRPKDFASLVGQEHVVRALTHALDGGRLHHAYLFTGTRGVGKTTLSRIFAKALNCETGVTSQPCGVCRACR 80
Cdd:PRK07003   1 MTYQVLARKWRPKDFASLVGQEHVVRALTHALDGGRLHHAYLFTGTRGVGKTTLSRIFAKALNCETGVTSQPCGVCRACR 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414  81 EIDEGRFVDYVEMDAASNRGVDEMAALLERAVYAPVDARFKVYMIDEVHMLTNHAFNAMLKTLEEPPPHVKFILATTDPQ 160
Cdd:PRK07003  81 EIDEGRFVDYVEMDAASNRGVDEMAALLERAVYAPVDARFKVYMIDEVHMLTNHAFNAMLKTLEEPPPHVKFILATTDPQ 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414 161 KIPVTVLSRCLQFNLKQMPAGHIVSHLERILGEEQITFEPQALRLLARAAQGSMRDALSLTDQAIAYSANEVTESAVSGM 240
Cdd:PRK07003 161 KIPVTVLSRCLQFNLKQMPAGHIVSHLERILGEERIAFEPQALRLLARAAQGSMRDALSLTDQAIAYSANEVTETAVSGM 240
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414 241 LGALDQTYMVRLLDALAAANGPEILAIADEMSLRSLSFSTALQDLASLLHRIAWAQFAPGSVLDEWPEAADLRRFAETLS 320
Cdd:PRK07003 241 LGALDQTYMVRLLDALAAGDGPEILAVADEMALRSLSFSTALQDLASLLHRIAWAQFAPASVLDEWPEAADLRRFAELLS 320
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414 321 PEQVQLFYQIATVGRAELGLAPDEYAGFTMTLLRMLAFEPAVGAGSAPGGQPSVPPR------AVPAPRAAAAPTAAAAK 394
Cdd:PRK07003 321 PEQVQLFYQIATVGRGELGLAPDEYAGFTMTLLRMLAFEPAVTGGGAPGGGVPARVAgavpapGARAAAAVGASAVPAVT 400
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414 395 PVSATPAGAA---RPQAAAPAAPAAPVARSAPAQSSDEAERPAAKPPAVQSPAEAAAPIPAAADAQAIELP-QPETKAAP 470
Cdd:PRK07003 401 AVTGAAGAALapkAAAAAAATRAEAPPAAPAPPATADRGDDAADGDAPVPAKANARASADSRCDERDAQPPaDSGSASAP 480
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414 471 AGDMPPPTRKEPEPPAV----------------AAVQRNDEPAPQAEPAPRAASPEPAAVRPAARAGGAAAALDVLRNAG 534
Cdd:PRK07003 481 ASDAPPDAAFEPAPRAAapsaatpaavpdarapAAASREDAPAAAAPPAPEARPPTPAAAAPAARAGGAAAALDVLRNAG 560
                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414 535 MRVSSDRGGRAGATAKPAAAQPAAEKPAAPRPAVQVPTPRAAARAPQAA-----------ESRQPSPPWEDIPPDDYVPL 603
Cdd:PRK07003 561 MRVSSDRGARAAAAAKPAAAPAAAPKPAAPRVAVQVPTPRARAATGDAPpngaaraeqaaESRGAPPPWEDIPPDDYVPL 640
                        650       660       670       680       690       700       710       720
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414 604 SADEMFGGSDDSFVPVFDSGPDDVRVTPKPAEtRPAAPIDTRPLPPAIALDPIGFDGEWPALAARLPLKGVAYQLAFNSE 683
Cdd:PRK07003 641 SADEGFGGPDDGFVPVFDSGPDDVRVAPKPAD-APAPPVDTRPLPPAIPLDAIGFDGEWPALAARLPLKGVAYQLAFNSE 719
                        730       740       750       760       770       780       790       800
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414 684 LTAVDASTLKLSVPVPQYADAAQVTKLKAALADALGKPVEVSVEVGPARRTAAALDAAARAARQREAEQEIHGDPFVQQL 763
Cdd:PRK07003 720 LTAADGGTLKLAVPVPQYADAAQVAKLKAALADALGKPVEVAVEVGPARRTAAALDAAERAKRQREAEQEIHADPFVQQL 799
                        810       820       830
                 ....*....|....*....|....*....|.
gi 924601414 764 VRDFGARIVEGSVRPLA--DSAPDGVPPTLH 792
Cdd:PRK07003 800 LREFGASIVEGSIRPVAaeAGAPDGASPTLH 830
PRK12323 PRK12323
DNA polymerase III subunit gamma/tau;
1-780 0e+00

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237057 [Multi-domain]  Cd Length: 700  Bit Score: 780.60  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414   1 MTYQVLARKWRPKDFASLVGQEHVVRALTHALDGGRLHHAYLFTGTRGVGKTTLSRIFAKALNC-----ETGVTSQPCGV 75
Cdd:PRK12323   1 MSYQVLARKWRPRDFTTLVGQEHVVRALTHALEQQRLHHAYLFTGTRGVGKTTLSRILAKSLNCtgadgEGGITAQPCGQ 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414  76 CRACREIDEGRFVDYVEMDAASNRGVDEMAALLERAVYAPVDARFKVYMIDEVHMLTNHAFNAMLKTLEEPPPHVKFILA 155
Cdd:PRK12323  81 CRACTEIDAGRFVDYIEMDAASNRGVDEMAQLLDKAVYAPTAGRFKVYMIDEVHMLTNHAFNAMLKTLEEPPEHVKFILA 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414 156 TTDPQKIPVTVLSRCLQFNLKQMPAGHIVSHLERILGEEQITFEPQALRLLARAAQGSMRDALSLTDQAIAYSANEVTES 235
Cdd:PRK12323 161 TTDPQKIPVTVLSRCLQFNLKQMPPGHIVSHLDAILGEEGIAHEVNALRLLAQAAQGSMRDALSLTDQAIAYSAGNVSEE 240
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414 236 AVSGMLGALDQTYMVRLLDALAAANGPEILAIADEMSLRSLSFSTALQDLASLLHRIAWAQFAPGSVLDEWPEAADLRRF 315
Cdd:PRK12323 241 AVRGMLGAIDQSYLVRLLDALAAEDGAALLAIADEMAGRSLSFAGALQDLASLLQKIALAQVVPAAVQDDWPEADDIRRL 320
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414 316 AETLSPEQVQLFYQIATVGRAELGLAPDEYAGFTMTLLRMLAFEPAVGAGSAPggqpsvppravpapraaaaptaaaakP 395
Cdd:PRK12323 321 AGRFDAQEVQLFYQIANLGRSELALAPDEYAGFTMTLLRMLAFRPGQSGGGAG--------------------------P 374
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414 396 VSAtpagaarpqaaapaapaapvarsapAQSSDEAERPAAKPPAVQSPAEAAAPIPAAadaqaielPQPETKAAPAGDMP 475
Cdd:PRK12323 375 ATA-------------------------AAAPVAQPAPAAAAPAAAAPAPAAPPAAPA--------AAPAAAAAARAVAA 421
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414 476 PPTRKEPEPPAVAAVQRNDEPAPQAEPAPRAASPepaaVRPAARAGGAAAALdvlrnagmrvssdrggragatakpaaaq 555
Cdd:PRK12323 422 APARRSPAPEALAAARQASARGPGGAPAPAPAPA----AAPAAAARPAAAGP---------------------------- 469
                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414 556 paaekpaAPRPAVQVPTPRAAARAPQAAESRQPSPPWEDIPPDDYVPLSADEMFGGSDDSFVPVFDSG---PDDVRVTPK 632
Cdd:PRK12323 470 -------RPVAAAAAAAPARAAPAAAPAPADDDPPPWEELPPEFASPAPAQPDAAPAGWVAESIPDPAtadPDDAFETLA 542
                        650       660       670       680       690       700       710       720
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414 633 PAETRPAAPIDTRPLPPAIALDP---------IGFDGEWPALAARLPLKGVAYQLAFNSELTAVDASTLKLSVPVPQYAD 703
Cdd:PRK12323 543 PAPAAAPAPRAAAATEPVVAPRPprasasglpDMFDGDWPALAARLPVRGLAQQLARQSELAGVEGDTVRLRVPVPALAE 622
                        730       740       750       760       770       780       790
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 924601414 704 AAQVTKLKAALADALGKPVEVSVEVGPARRTAAALDAAARAARQREAEQEIHGDPFVQQLVRDFGARIVEGSVRPLA 780
Cdd:PRK12323 623 AEVVERLQAALTEHFGQPVRVVCEVGAVGATAAAVDAEERAERQRAAEDAIAADPFVQALVRDFGGQVVPGSIQPHA 699
PRK14951 PRK14951
DNA polymerase III subunits gamma and tau; Provisional
1-779 0e+00

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237865 [Multi-domain]  Cd Length: 618  Bit Score: 701.86  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414   1 MTYQVLARKWRPKDFASLVGQEHVVRALTHALDGGRLHHAYLFTGTRGVGKTTLSRIFAKALNC-----ETGVTSQPCGV 75
Cdd:PRK14951   1 MSYLVLARKYRPRSFSEMVGQEHVVQALTNALTQQRLHHAYLFTGTRGVGKTTVSRILAKSLNCqgpdgQGGITATPCGV 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414  76 CRACREIDEGRFVDYVEMDAASNRGVDEMAALLERAVYAPVDARFKVYMIDEVHMLTNHAFNAMLKTLEEPPPHVKFILA 155
Cdd:PRK14951  81 CQACRDIDSGRFVDYTELDAASNRGVDEVQQLLEQAVYKPVQGRFKVFMIDEVHMLTNTAFNAMLKTLEEPPEYLKFVLA 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414 156 TTDPQKIPVTVLSRCLQFNLKQMPAGHIVSHLERILGEEQITFEPQALRLLARAAQGSMRDALSLTDQAIAYSANEVTES 235
Cdd:PRK14951 161 TTDPQKVPVTVLSRCLQFNLRPMAPETVLEHLTQVLAAENVPAEPQALRLLARAARGSMRDALSLTDQAIAFGSGQLQEA 240
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414 236 AVSGMLGALDQTYMVRLLDALAAANGPEILAIADEMSLRSLSFSTALQDLASLLHRIAWAQFAPGSVLDEW-PEAADLRR 314
Cdd:PRK14951 241 AVRQMLGSVDRSHVFRLIDALAQGDGRTVVETADELRLNGLSAASTLEEMAAVLQRMAVLQAVPQAAAAATdPEAAEVAR 320
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414 315 FAETLSPEQVQLFYQIATVGRAELGLAPDEYAGFTMTLLRMLAFEPAVGAGSAPGGQPSVPPravpapraaaaptaaaak 394
Cdd:PRK14951 321 LAALMPADETQLLYSICLHGRAELGLAPDEYAALTMVLLRLLAFKPAAAAEAAAPAEKKTPA------------------ 382
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414 395 pvsatpagaarpqaaapaapaapvarsapaqssdeaeRPAAKPPAVQspaeaaapipaaadaqaielPQPETKAAPAGDM 474
Cdd:PRK14951 383 -------------------------------------RPEAAAPAAA--------------------PVAQAAAAPAPAA 405
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414 475 PPPTRKEPEPPAVAAVqrndEPAPQAEPAPRAASPepaavrpaaraggaaaaldvlrnagmrvssdrggragatakpaaa 554
Cdd:PRK14951 406 APAAAASAPAAPPAAA----PPAPVAAPAAAAPAA--------------------------------------------- 436
                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414 555 qpaaekpaaprpavqVPTPRAAARAPQAAESRQPSPPWEDIPpddyvplsademfggsddsfvpvfdsgpddVRVTPKPA 634
Cdd:PRK14951 437 ---------------APAAAPAAVALAPAPPAQAAPETVAIP------------------------------VRVAPEPA 471
                        650       660       670       680       690       700       710       720
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414 635 ETRPAAPIDTRPLPPAIALDPIG--FDGEWPALAARLPLKGVAYQLAFNSELTAVDASTLKLSVPVPQYADAAQVTKLKA 712
Cdd:PRK14951 472 VASAAPAPAAAPAAARLTPTEEGdvWHATVQQLAAAEAITALARELALQSELVARDGDQWLLRVERESLNQPGARERLRA 551
                        730       740       750       760       770       780
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 924601414 713 ALADALGKPVEVSVEVGPARRTAAALDAAARAARQREAEQEIHGDPFVQQLVRDFGARIVEGSVRPL 779
Cdd:PRK14951 552 ALEAALGHAVRLEVEVGAVTDSPARRNAAARAERQREAEEIIRNDPFVQQLMRDFGAKIVPGSIKPV 618
PRK14969 PRK14969
DNA polymerase III subunits gamma and tau; Provisional
1-373 0e+00

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237873 [Multi-domain]  Cd Length: 527  Bit Score: 662.60  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414   1 MTYQVLARKWRPKDFASLVGQEHVVRALTHALDGGRLHHAYLFTGTRGVGKTTLSRIFAKALNCETGVTSQPCGVCRACR 80
Cdd:PRK14969   1 MSYQVLARKWRPKSFSELVGQEHVVRALTNALEQQRLHHAYLFTGTRGVGKTTLARILAKSLNCETGVTATPCGVCSACL 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414  81 EIDEGRFVDYVEMDAASNRGVDEMAALLERAVYAPVDARFKVYMIDEVHMLTNHAFNAMLKTLEEPPPHVKFILATTDPQ 160
Cdd:PRK14969  81 EIDSGRFVDLIEVDAASNTQVDAMRELLDNAQYAPTRGRFKVYIIDEVHMLSKSAFNAMLKTLEEPPEHVKFILATTDPQ 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414 161 KIPVTVLSRCLQFNLKQMPAGHIVSHLERILGEEQITFEPQALRLLARAAQGSMRDALSLTDQAIAYSANEVTESAVSGM 240
Cdd:PRK14969 161 KIPVTVLSRCLQFNLKQMPPPLIVSHLQHILEQENIPFDATALQLLARAAAGSMRDALSLLDQAIAYGGGTVNESEVRAM 240
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414 241 LGALDQTYMVRLLDALAAANGPEILAIADEMSLRSLSFSTALQDLASLLHRIAWAQFAPGSVLDEWPEAADLRRFAETLS 320
Cdd:PRK14969 241 LGAIDQDYLFALLEALLAQDGAALLAIADAMEERSLSFDAALQDLAALLHRLAIAQTVPDSIADDLPERDRLLDLAKRLS 320
                        330       340       350       360       370
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 924601414 321 PEQVQLFYQIATVGRAELGLAPDEYAGFTMTLLRMLAFEP---AVGAGSAPGGQPS 373
Cdd:PRK14969 321 PEDIQLYYQIALHGRRDLGLAPDEYAGFTMTLLRMLAFRPseqDSGAGRAPGAVPG 376
PRK07994 PRK07994
DNA polymerase III subunits gamma and tau; Validated
1-779 0e+00

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236138 [Multi-domain]  Cd Length: 647  Bit Score: 647.31  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414   1 MTYQVLARKWRPKDFASLVGQEHVVRALTHALDGGRLHHAYLFTGTRGVGKTTLSRIFAKALNCETGVTSQPCGVCRACR 80
Cdd:PRK07994   1 MSYQVLARKWRPQTFAEVVGQEHVLTALANALDLGRLHHAYLFSGTRGVGKTTIARLLAKGLNCETGITATPCGECDNCR 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414  81 EIDEGRFVDYVEMDAASNRGVDEMAALLERAVYAPVDARFKVYMIDEVHMLTNHAFNAMLKTLEEPPPHVKFILATTDPQ 160
Cdd:PRK07994  81 EIEQGRFVDLIEIDAASRTKVEDTRELLDNVQYAPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPEHVKFLLATTDPQ 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414 161 KIPVTVLSRCLQFNLKQMPAGHIVSHLERILGEEQITFEPQALRLLARAAQGSMRDALSLTDQAIAYSANEVTESAVSGM 240
Cdd:PRK07994 161 KLPVTILSRCLQFHLKALDVEQIRQQLEHILQAEQIPFEPRALQLLARAADGSMRDALSLTDQAIASGNGQVTTDDVSAM 240
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414 241 LGALDQTYMVRLLDALAAANGPEILAIADEMSLRSLSFSTALQDLASLLHRIAWAQFAPGSVLDEWPEAA-DLRRFAETL 319
Cdd:PRK07994 241 LGTLDDDQALSLLEALVEGDGERVMALINQLAERGPDWEGLLVELLELLHRIAMAQLLPAALDNDMADIElRLRELARTL 320
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414 320 SPEQVQLFYQIATVGRAELGLAPDEYAGFTMTLLRMLAFEPAVGAGSAPGGQPSVPPRAVPAPRAAAAPTAAAAKPVSAt 399
Cdd:PRK07994 321 PPEDVQLYYQTLLIGRKDLPLAPDRRMGVEMTLLRMLAFHPAAPLPEPEVPPQSAAPAASAQATAAPTAAVAPPQAPAV- 399
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414 400 pagaarpqaaapaapaapvarsapaqssdeAERPAAKPPAVQSPAEAAAPIPAAADAQAIELPQPETKAAPagdmPPPTR 479
Cdd:PRK07994 400 ------------------------------PPPPASAPQQAPAVPLPETTSQLLAARQQLQRAQGATKAKK----SEPAA 445
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414 480 KEPEPPAVAAVQRNDEPAPQAEPAPRAASPEpaavrpaaraggaaaaldvlrnagmrvssdrggragatakpaaaqpaae 559
Cdd:PRK07994 446 ASRARPVNSALERLASVRPAPSALEKAPAKK------------------------------------------------- 476
                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414 560 kpaaprpavqvptpraaarapqaaesrqPSPPWEDIPPDDYVPLSAdemfggsddsfvpvfdsgpddvrVTPKpAETRPA 639
Cdd:PRK07994 477 ----------------------------EAYRWKATNPVEVKKEPV-----------------------ATPK-ALKKAL 504
                        650       660       670       680       690       700       710       720
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414 640 APIDTRPLPPAIALDPIGFDgEWPALAARLPLKGVAYQLAFNSELTAVDASTLKLSVPvPQYA---DAAQVTKLKAALAD 716
Cdd:PRK07994 505 EHEKTPELAAKLAAEAIERD-PWAALVSQLGLPGLVEQLALNAWKEEHDNGEVCLHLR-PSQRhlnSPRAQQRLAEALSE 582
                        730       740       750       760       770       780
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 924601414 717 ALGKPVEVSVEVG--PARRTAAALDAAARAARQREAEQEIHGDPFVQQLVRDFGARIVEGSVRPL 779
Cdd:PRK07994 583 LLGRTVELTIEEDdnPAVETPLEWRQRIYEEKLAQAEESIIADPNIQTLRQFFDAELDEDSIRPI 647
PRK08691 PRK08691
DNA polymerase III subunits gamma and tau; Validated
1-781 1.20e-178

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236333 [Multi-domain]  Cd Length: 709  Bit Score: 529.67  E-value: 1.20e-178
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414   1 MTYQVLARKWRPKDFASLVGQEHVVRALTHALDGGRLHHAYLFTGTRGVGKTTLSRIFAKALNCETGVTSQPCGVCRACR 80
Cdd:PRK08691   1 MAYQVLARKWRPKTFADLVGQEHVVKALQNALDEGRLHHAYLLTGTRGVGKTTIARILAKSLNCENAQHGEPCGVCQSCT 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414  81 EIDEGRFVDYVEMDAASNRGVDEMAALLERAVYAPVDARFKVYMIDEVHMLTNHAFNAMLKTLEEPPPHVKFILATTDPQ 160
Cdd:PRK08691  81 QIDAGRYVDLLEIDAASNTGIDNIREVLENAQYAPTAGKYKVYIIDEVHMLSKSAFNAMLKTLEEPPEHVKFILATTDPH 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414 161 KIPVTVLSRCLQFNLKQMPAGHIVSHLERILGEEQITFEPQALRLLARAAQGSMRDALSLTDQAIAYSANEVTESAVSGM 240
Cdd:PRK08691 161 KVPVTVLSRCLQFVLRNMTAQQVADHLAHVLDSEKIAYEPPALQLLGRAAAGSMRDALSLLDQAIALGSGKVAENDVRQM 240
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414 241 LGALDQTYMVRLLDALAAANGPEILAIADEMSLRSLSFSTALQDLASLLHRIAWAQFAPGSVLDEWPEAADLRRFAETLS 320
Cdd:PRK08691 241 IGAVDKQYLYELLTGIINQDGAALLAKAQEMAACAVGFDNALGELAILLQQLALIQAVPSALAHDDPDSDILHRLAQTIS 320
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414 321 PEQVQLFYQIATVGRAELGLAPDEYAGFTMTLLRMLAFEPAVGAG-SAPGGQPSVPPRAVPAPRAAAAPTAAAAKPVSAT 399
Cdd:PRK08691 321 GEQIQLYYQIAVHGKRDLSLAPDEYAGFMMTLLRMLAFAPLAAAScDANAVIENTELQSPSAQTAEKETAAKKPQPRPEA 400
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414 400 pagaarpqaaapaapaapvarsAPAQSSDEAERPAAKPPAVQSPaeaaapipaaadaqaielpQPETKAAPAgDMPPptr 479
Cdd:PRK08691 401 ----------------------ETAQTPVQTASAAAMPSEGKTA-------------------GPVSNQENN-DVPP--- 435
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414 480 kepeppavaavqRNDEPAPQAEPAPRAASPEPAAVRPAARAGGAAAALDVLRNAGMRVSSDRGGRAGATAKPAAAQPAAE 559
Cdd:PRK08691 436 ------------WEDAPDEAQTAAGTAQTSAKSIQTASEAETPPENQVSKNKAADNETDAPLSEVPSENPIQATPNDEAV 503
                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414 560 KPAAPRPAVQVPTPRAAARAPQAAESRQ----PSPPWEDIPPddyvplsADEMFGGSDDSFVPVFDSGPddvrvtPKPAE 635
Cdd:PRK08691 504 ETETFAHEAPAEPFYGYGFPDNDCPPEDgaeiPPPDWEHAAP-------ADTAGGGADEEAEAGGIGGN------NTPSA 570
                        650       660       670       680       690       700       710       720
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414 636 trpaapidtrplPPaialdPIGFDGEWPALAARLPLK-GVAYQLAFNSELTAVDASTLKLSVPVPQ----YADAAQVTKL 710
Cdd:PRK08691 571 ------------PP-----PEFSTENWAAIVRHFARKlGAAQMPAQHSAWTEYHPDTGLMVLAMTAearaTADKKRLDKI 633
                        730       740       750       760       770       780       790
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 924601414 711 KAALADALGKPVEVSVE--VGPARRTAAALDAAARAARQREAEQE-IHGDPFVQQLVRDFGARIVEGSVRPLAD 781
Cdd:PRK08691 634 RDTLAQAYGLQLTLQTQdwRDEAGRETPAMQDKRVQAEDRQKAQAlLEADPAAQKILQAFGAQWQPESLELAAN 707
DnaX COG2812
DNA polymerase III, gamma/tau subunits [Replication, recombination and repair];
1-357 2.78e-167

DNA polymerase III, gamma/tau subunits [Replication, recombination and repair];


Pssm-ID: 442061 [Multi-domain]  Cd Length: 340  Bit Score: 486.24  E-value: 2.78e-167
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414   1 MTYQVlarkwrPKDFASLVGQEHVVRALTHALDGGRLHHAYLFTGTRGVGKTTLSRIFAKALNCETGVTSQPCGVCRACR 80
Cdd:COG2812    1 MSYQV------PQTFDDVVGQEHVVRTLKNALASGRLAHAYLFTGPRGVGKTTLARILAKALNCENGPTGEPCGECESCR 74
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414  81 EIDEGRFVDYVEMDA-ASNRGVDEMAALLERAVYAPVDARFKVYMIDEVHMLTNHAFNAMLKTLEEPPPHVKFILATTDP 159
Cdd:COG2812   75 AIAAGSHPDVIEIDAeASNIGVDDIRELIEKVSYAPVEGRYKVYIIDEAHMLTTEAFNALLKTLEEPPPHVVFILATTEP 154
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414 160 QKIPVTVLSRCLQFNLKQMPAGHIVSHLERILGEEQITFEPQALRLLARAAQGSMRDALSLTDQAIAYsanevtesavsg 239
Cdd:COG2812  155 QKLLPTILSRCQRFDFRRLPPEEIAEHLAKIAEREGIEIEPEALALIARAADGSMRDALSLLDQAIAF------------ 222
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414 240 mlGALD-QTYMVRLLDALAAANGPEILAIADEMSLRSLSFSTALQDLASLLHRIAWAQFAPGS-VLDEWPEAADLRRFAE 317
Cdd:COG2812  223 --GLLDrRELLLDLLEALLAGDVAALLALAEELAKRGRDLKRFLDDLLSLLRDLLLLKLGPDAeLLVNEDERERLQELAR 300
                        330       340       350       360
                 ....*....|....*....|....*....|....*....|
gi 924601414 318 TLSPEQVQLFYQIATVGRAELGLAPDEYAGFTMTLLRMLA 357
Cdd:COG2812  301 RLSPERLLRAIQILLEARRELERNVNPRLALEMLLLRLAR 340
dnaX_nterm TIGR02397
DNA polymerase III, subunit gamma and tau; This model represents the well-conserved first ~ ...
3-356 1.48e-166

DNA polymerase III, subunit gamma and tau; This model represents the well-conserved first ~ 365 amino acids of the translation of the dnaX gene. The full-length product of the dnaX gene in the model bacterium E. coli is the DNA polymerase III tau subunit. A translational frameshift leads to early termination and a truncated protein subunit gamma, about 1/3 shorter than tau and present in roughly equal amounts. This frameshift mechanism is not necessarily universal for species with DNA polymerase III but appears conserved in the exterme thermophile Thermus thermophilis. [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 274111 [Multi-domain]  Cd Length: 355  Bit Score: 485.15  E-value: 1.48e-166
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414    3 YQVLARKWRPKDFASLVGQEHVVRALTHALDGGRLHHAYLFTGTRGVGKTTLSRIFAKALNCETGVTSQPCGVCRACREI 82
Cdd:TIGR02397   1 YQVLARKYRPQTFEDVIGQEHIVQTLKNAIKNGRIAHAYLFSGPRGTGKTSIARIFAKALNCQNGPDGEPCNECESCKEI 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414   83 DEGRFVDYVEMDAASNRGVDEMAALLERAVYAPVDARFKVYMIDEVHMLTNHAFNAMLKTLEEPPPHVKFILATTDPQKI 162
Cdd:TIGR02397  81 NSGSSLDVIEIDAASNNGVDDIREILDNVKYAPSSGKYKVYIIDEVHMLSKSAFNALLKTLEEPPEHVVFILATTEPHKI 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414  163 PVTVLSRCLQFNLKQMPAGHIVSHLERILGEEQITFEPQALRLLARAAQGSMRDALSLTDQAIAYSANEVTESAVSGMLG 242
Cdd:TIGR02397 161 PATILSRCQRFDFKRIPLEDIVERLKKILDKEGIKIEDEALELIARAADGSLRDALSLLDQLISFGNGKITYEDVNELLG 240
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414  243 ALDQTYMVRLLDALAAANGPEILAIADEMSLRSLSFSTALQDLASLLHRIAWAQFAPGSVL-DEWPEAADLRRFAETLSP 321
Cdd:TIGR02397 241 LVDDEKLIELLEAILNKDTAEALKILDEILESGVDPEKFLEDLIEILRDLLLIKKTPSNLLaVLESEQEFLKELALKLSL 320
                         330       340       350
                  ....*....|....*....|....*....|....*
gi 924601414  322 EQVQLFYQIATVGRAELGLAPDEYAGFTMTLLRML 356
Cdd:TIGR02397 321 EFLLRLLDILLEALKDLRFSNDPRIWLEMTLLRLL 355
PRK14949 PRK14949
DNA polymerase III subunits gamma and tau; Provisional
1-360 6.32e-156

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237863 [Multi-domain]  Cd Length: 944  Bit Score: 478.45  E-value: 6.32e-156
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414   1 MTYQVLARKWRPKDFASLVGQEHVVRALTHALDGGRLHHAYLFTGTRGVGKTTLSRIFAKALNCETGVTSQPCGVCRACR 80
Cdd:PRK14949   1 MSYQVLARKWRPATFEQMVGQSHVLHALTNALTQQRLHHAYLFTGTRGVGKTSLARLFAKGLNCEQGVTATPCGVCSSCV 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414  81 EIDEGRFVDYVEMDAASNRGVDEMAALLERAVYAPVDARFKVYMIDEVHMLTNHAFNAMLKTLEEPPPHVKFILATTDPQ 160
Cdd:PRK14949  81 EIAQGRFVDLIEVDAASRTKVDDTRELLDNVQYRPSRGRFKVYLIDEVHMLSRSSFNALLKTLEEPPEHVKFLLATTDPQ 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414 161 KIPVTVLSRCLQFNLKQMPAGHIVSHLERILGEEQITFEPQALRLLARAAQGSMRDALSLTDQAIAYSANEVTESAVSGM 240
Cdd:PRK14949 161 KLPVTVLSRCLQFNLKSLTQDEIGTQLNHILTQEQLPFEAEALTLLAKAANGSMRDALSLTDQAIAFGGGQVMLTQVQTM 240
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414 241 LGALDQTYMVRLLDALAAANgpeilaIADEM--SLRSLSFST----ALQDLASLLHRIAWAQFAPGsvldewpeAADL-- 312
Cdd:PRK14949 241 LGSIDEQHVIALLKALTDAD------IGVLMqtCAQVLAFGAdaqeVLRSLLELLHQITLTQFAPA--------AAQQsl 306
                        330       340       350       360       370
                 ....*....|....*....|....*....|....*....|....*....|...
gi 924601414 313 -----RRFAETLSPEQVQLFYQIATVGRAELGLAPDEYAGFTMTLLRMLAFEP 360
Cdd:PRK14949 307 yseqiRAFAEQLSPEQVQLYYQILLTGRKDLPHAPDPKSGLEMALLRAVAFVP 359
PRK14960 PRK14960
DNA polymerase III subunit gamma/tau;
3-504 2.39e-135

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237868 [Multi-domain]  Cd Length: 702  Bit Score: 417.53  E-value: 2.39e-135
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414   3 YQVLARKWRPKDFASLVGQEHVVRALTHALDGGRLHHAYLFTGTRGVGKTTLSRIFAKALNCETGVTSQPCGVCRACREI 82
Cdd:PRK14960   2 YQVLARKYRPRNFNELVGQNHVSRALSSALERGRLHHAYLFTGTRGVGKTTIARILAKCLNCETGVTSTPCEVCATCKAV 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414  83 DEGRFVDYVEMDAASNRGVDEMAALLERAVYAPVDARFKVYMIDEVHMLTNHAFNAMLKTLEEPPPHVKFILATTDPQKI 162
Cdd:PRK14960  82 NEGRFIDLIEIDAASRTKVEDTRELLDNVPYAPTQGRFKVYLIDEVHMLSTHSFNALLKTLEEPPEHVKFLFATTDPQKL 161
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414 163 PVTVLSRCLQFNLKQMPAGHIVSHLERILGEEQITFEPQALRLLARAAQGSMRDALSLTDQAIAYSANEVTESAVSGMLG 242
Cdd:PRK14960 162 PITVISRCLQFTLRPLAVDEITKHLGAILEKEQIAADQDAIWQIAESAQGSLRDALSLTDQAIAYGQGAVHHQDVKEMLG 241
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414 243 ALDQTYMVRLLDALAAANGPEILAIADEMSLRSLSFSTALQDLASLLHRIAWAQFAPGSVLDEWPEA-ADLRRFAETLSP 321
Cdd:PRK14960 242 LIDRTIIYDLILAVHQNQREKVSQLLLQFRYQALDVSLVLDQLISTLHELALLQYLPELGLKYSEEInAKILQLSKLISA 321
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414 322 EQVQLFYQIATVGRAELGLAPDEYAGFTMTLLRMLAFEP------AVGAGSAPGGQpsvppravpapraaaaptaaaakp 395
Cdd:PRK14960 322 QDLQLYYQIACKGRSDLQLAVTQEQGFEMCVLRLLAFRPlapneiLVSEPVQQNGQ------------------------ 377
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414 396 vsatpagaarpqaaapaapAAPVARSAPAQSSDEAERPAAKPPAVQSpaeaaapipaaadAQAIELPQPETKAAPAGDMP 475
Cdd:PRK14960 378 -------------------AEVGLNSQAQTAQEITPVSAVQPVEVIS-------------QPAMVEPEPEPEPEPEPEPE 425
                        490       500
                 ....*....|....*....|....*....
gi 924601414 476 PPTRKEPEPpavaavqrndEPAPQAEPAP 504
Cdd:PRK14960 426 PEPEPEPEP----------EPEPEPEPQP 444
PRK05563 PRK05563
DNA polymerase III subunits gamma and tau; Validated
1-271 2.07e-133

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 235505 [Multi-domain]  Cd Length: 559  Bit Score: 407.72  E-value: 2.07e-133
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414   1 MTYQVLARKWRPKDFASLVGQEHVVRALTHALDGGRLHHAYLFTGTRGVGKTTLSRIFAKALNCETGVTSQPCGVCRACR 80
Cdd:PRK05563   1 MMYQALYRKWRPQTFEDVVGQEHITKTLKNAIKQGKISHAYLFSGPRGTGKTSAAKIFAKAVNCLNPPDGEPCNECEICK 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414  81 EIDEGRFVDYVEMDAASNRGVDEMAALLERAVYAPVDARFKVYMIDEVHMLTNHAFNAMLKTLEEPPPHVKFILATTDPQ 160
Cdd:PRK05563  81 AITNGSLMDVIEIDAASNNGVDEIRDIRDKVKYAPSEAKYKVYIIDEVHMLSTGAFNALLKTLEEPPAHVIFILATTEPH 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414 161 KIPVTVLSRCLQFNLKQMPAGHIVSHLERILGEEQITFEPQALRLLARAAQGSMRDALSLTDQAIAYSANEVTESAVSGM 240
Cdd:PRK05563 161 KIPATILSRCQRFDFKRISVEDIVERLKYILDKEGIEYEDEALRLIARAAEGGMRDALSILDQAISFGDGKVTYEDALEV 240
                        250       260       270
                 ....*....|....*....|....*....|.
gi 924601414 241 LGALDQTYMVRLLDALAAANGPEILAIADEM 271
Cdd:PRK05563 241 TGSVSQEALDDLVDAIVEGDVAKALKILEEL 271
PRK14961 PRK14961
DNA polymerase III subunits gamma and tau; Provisional
1-360 3.11e-131

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 184925 [Multi-domain]  Cd Length: 363  Bit Score: 394.95  E-value: 3.11e-131
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414   1 MTYQVLARKWRPKDFASLVGQEHVVRALTHALDGGRLHHAYLFTGTRGVGKTTLSRIFAKALNCETGVTSQPCGVCRACR 80
Cdd:PRK14961   1 MNYQILARKWRPQYFRDIIGQKHIVTAISNGLSLGRIHHAWLLSGTRGVGKTTIARLLAKSLNCQNGITSNPCRKCIICK 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414  81 EIDEGRFVDYVEMDAASNRGVDEMAALLERAVYAPVDARFKVYMIDEVHMLTNHAFNAMLKTLEEPPPHVKFILATTDPQ 160
Cdd:PRK14961  81 EIEKGLCLDLIEIDAASRTKVEEMREILDNIYYSPSKSRFKVYLIDEVHMLSRHSFNALLKTLEEPPQHIKFILATTDVE 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414 161 KIPVTVLSRCLQFNLKQMPAGHIVSHLERILGEEQITFEPQALRLLARAAQGSMRDALSLTDQAIAYSANEVTESAVSGM 240
Cdd:PRK14961 161 KIPKTILSRCLQFKLKIISEEKIFNFLKYILIKESIDTDEYALKLIAYHAHGSMRDALNLLEHAINLGKGNINIKNVTDM 240
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414 241 LGALDQTYMVRLLDALAAANGPEILAIADEMSLRSLSFSTALQDLASLLHRIAWAQFAPgsvlDEWPE------AADLRR 314
Cdd:PRK14961 241 LGLLNEKQSFLLTDALLKKDSKKTMLLLNKISSIGIEWENILIEMLRFLHHISMSQSFP----KIWNTifiknyKNQIQK 316
                        330       340       350       360
                 ....*....|....*....|....*....|....*....|....*.
gi 924601414 315 FAETLSPEQVQLFYQIATVGRAELGLAPDEYAGFTMTLLRMLAFEP 360
Cdd:PRK14961 317 IAQNNKKTNIQLCYQILLNGRKELKFAPDQKIGVEMTLLRAINAIT 362
PRK14958 PRK14958
DNA polymerase III subunits gamma and tau; Provisional
1-361 2.53e-128

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 184922 [Multi-domain]  Cd Length: 509  Bit Score: 392.94  E-value: 2.53e-128
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414   1 MTYQVLARKWRPKDFASLVGQEHVVRALTHALDGGRLHHAYLFTGTRGVGKTTLSRIFAKALNCETGVTSQPCGVCRACR 80
Cdd:PRK14958   1 MAHQVLARKWRPRCFQEVIGQAPVVRALSNALDQQYLHHAYLFTGTRGVGKTTISRILAKCLNCEKGVSANPCNDCENCR 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414  81 EIDEGRFVDYVEMDAASNRGVDEMAALLERAVYAPVDARFKVYMIDEVHMLTNHAFNAMLKTLEEPPPHVKFILATTDPQ 160
Cdd:PRK14958  81 EIDEGRFPDLFEVDAASRTKVEDTRELLDNIPYAPTKGRFKVYLIDEVHMLSGHSFNALLKTLEEPPSHVKFILATTDHH 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414 161 KIPVTVLSRCLQFNLKQMPAGHIVSHLERILGEEQITFEPQALRLLARAAQGSMRDALSLTDQAIAYSANEVTESAVSGM 240
Cdd:PRK14958 161 KLPVTVLSRCLQFHLAQLPPLQIAAHCQHLLKEENVEFENAALDLLARAANGSVRDALSLLDQSIAYGNGKVLIADVKTM 240
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414 241 LGALDQTYMVRLLDALAAANGPEILAIADEMSLRSLSFSTALQDLASLLHRIAWAQFAPGSVLDEwpEAADLRRFAETLS 320
Cdd:PRK14958 241 LGTIEPLLLFDILEALAAKAGDRLLGCVTRLVEQGVDFSNALADLLSLLHQIAIIQTVPEALIEN--DSEQLRQLAKLLD 318
                        330       340       350       360
                 ....*....|....*....|....*....|....*....|.
gi 924601414 321 PEQVQLFYQIATVGRAELGLAPDEYAGFTMTLLRMLAFEPA 361
Cdd:PRK14958 319 REDVQLFYQIGLIGQRDLAYSPTPQTGFEMTLLRMLAFYPS 359
PRK08451 PRK08451
DNA polymerase III subunits gamma and tau; Validated
4-272 2.51e-125

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236267 [Multi-domain]  Cd Length: 535  Bit Score: 385.93  E-value: 2.51e-125
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414   4 QVLARKWRPKDFASLVGQEHVVRALTHALDGGRLHHAYLFTGTRGVGKTTLSRIFAKALNCETGVTSQPCGVCRACREID 83
Cdd:PRK08451   2 QALALKYRPKHFDELIGQESVSKTLSLALDNNRLAHAYLFSGLRGSGKTSSARIFARALVCEQGPSSTPCDTCIQCQSAL 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414  84 EGRFVDYVEMDAASNRGVDEMAALLERAVYAPVDARFKVYMIDEVHMLTNHAFNAMLKTLEEPPPHVKFILATTDPQKIP 163
Cdd:PRK08451  82 ENRHIDIIEMDAASNRGIDDIRELIEQTKYKPSMARFKIFIIDEVHMLTKEAFNALLKTLEEPPSYVKFILATTDPLKLP 161
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414 164 VTVLSRCLQFNLKQMPAGHIVSHLERILGEEQITFEPQALRLLARAAQGSMRDALSLTDQAIAYSANEVTESAVSGMLGA 243
Cdd:PRK08451 162 ATILSRTQHFRFKQIPQNSIISHLKTILEKEGVSYEPEALEILARSGNGSLRDTLTLLDQAIIYCKNAITESKVADMLGL 241
                        250       260
                 ....*....|....*....|....*....
gi 924601414 244 LDQTYMVRLLDALAAANGPEILAIADEMS 272
Cdd:PRK08451 242 LDPSKLEDFFQAILNQDKEKLFELLKELE 270
PRK09111 PRK09111
DNA polymerase III subunits gamma and tau; Validated
2-398 3.77e-125

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236382 [Multi-domain]  Cd Length: 598  Bit Score: 387.33  E-value: 3.77e-125
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414   2 TYQVLARKWRPKDFASLVGQEHVVRALTHALDGGRLHHAYLFTGTRGVGKTTLSRIFAKALNCET-----GVTSQPCGVC 76
Cdd:PRK09111  10 PYRVLARKYRPQTFDDLIGQEAMVRTLTNAFETGRIAQAFMLTGVRGVGKTTTARILARALNYEGpdgdgGPTIDLCGVG 89
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414  77 RACREIDEGRFVDYVEMDAASNRGVDEMAALLERAVYAPVDARFKVYMIDEVHMLTNHAFNAMLKTLEEPPPHVKFILAT 156
Cdd:PRK09111  90 EHCQAIMEGRHVDVLEMDAASHTGVDDIREIIESVRYRPVSARYKVYIIDEVHMLSTAAFNALLKTLEEPPPHVKFIFAT 169
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414 157 TDPQKIPVTVLSRCLQFNLKQMPAGHIVSHLERILGEEQITFEPQALRLLARAAQGSMRDALSLTDQAIAYSANEVTESA 236
Cdd:PRK09111 170 TEIRKVPVTVLSRCQRFDLRRIEADVLAAHLSRIAAKEGVEVEDEALALIARAAEGSVRDGLSLLDQAIAHGAGEVTAEA 249
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414 237 VSGMLGALDQTYMVRLLDALAAANGPEILAIADEMSLRSLSFSTALQDLASLLHRIAWAQFAPGSVLD------EWPEAA 310
Cdd:PRK09111 250 VRDMLGLADRARVIDLFEALMRGDVAAALAEFRAQYDAGADPVVVLTDLAEFTHLVTRLKIVPDAAEDpslseaERTRGA 329
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414 311 DlrrFAETLSPEQVQLFYQIATVGRAELGLAPDEYAGFTMTL---------------LRMLAFEPAV---GAGSAPGGQP 372
Cdd:PRK09111 330 E---FAKKLSMRVLSRLWQMLLKGIEEVQGAPRPLAAAEMVLirlayaadlptpdeaLRRLQEGPPSpggGGGGPPGGGG 406
                        410       420
                 ....*....|....*....|....*.
gi 924601414 373 SVPPRAVPAPRAAAAPTAAAAKPVSA 398
Cdd:PRK09111 407 APGAPAAAAAPGAAAAAPAAGGPAAA 432
PRK14965 PRK14965
DNA polymerase III subunits gamma and tau; Provisional
1-362 1.73e-121

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237871 [Multi-domain]  Cd Length: 576  Bit Score: 377.16  E-value: 1.73e-121
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414   1 MTYQVLARKWRPKDFASLVGQEHVVRALTHALDGGRLHHAYLFTGTRGVGKTTLSRIFAKALNCETGVTSQPCGVCRACR 80
Cdd:PRK14965   1 MSYLVLARKYRPQTFSDLTGQEHVSRTLQNAIDTGRVAHAFLFTGARGVGKTSTARILAKALNCEQGLTAEPCNVCPPCV 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414  81 EIDEGRFVDYVEMDAASNRGVDEMAALLERAVYAPVDARFKVYMIDEVHMLTNHAFNAMLKTLEEPPPHVKFILATTDPQ 160
Cdd:PRK14965  81 EITEGRSVDVFEIDGASNTGVDDIRELRENVKYLPSRSRYKIFIIDEVHMLSTNAFNALLKTLEEPPPHVKFIFATTEPH 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414 161 KIPVTVLSRCLQFNLKQMPAGHIVSHLERILGEEQITFEPQALRLLARAAQGSMRDALSLTDQAIAYSANEVTESAVSGM 240
Cdd:PRK14965 161 KVPITILSRCQRFDFRRIPLQKIVDRLRYIADQEGISISDAALALVARKGDGSMRDSLSTLDQVLAFCGDAVGDDDVAEL 240
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414 241 LGALDQTYMVRLLDALAAANGPEILAIADEMSLRSLSFSTALQDLASLLHR--IAWAQFAPGSVLD-EWPEAADLRRFAE 317
Cdd:PRK14965 241 LGVVDRRLLLDISAAVFGRDTRALLEIVERVDEFGYNMRQFCQELIDHLRNlvVLRAVGEPGDLLDlSEAELAELRAQAA 320
                        330       340       350       360
                 ....*....|....*....|....*....|....*....|....*
gi 924601414 318 TLSPEQVQLFYQIATVGRAELGLAPDEYAGFTMTLLRMLAFEPAV 362
Cdd:PRK14965 321 AADAADLQRHLTLLLRAEGEMAHASFPRLVLEMALLKMATLAPGA 365
PRK14953 PRK14953
DNA polymerase III subunits gamma and tau; Provisional
1-319 1.31e-112

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237867 [Multi-domain]  Cd Length: 486  Bit Score: 351.05  E-value: 1.31e-112
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414   1 MTYQVLARKWRPKDFASLVGQEHVVRALTHALDGGRLHHAYLFTGTRGVGKTTLSRIFAKALNCETGVTSQPCGVCRACR 80
Cdd:PRK14953   1 MMYIPFARKYRPKFFKEVIGQEIVVRILKNAVKLQRVSHAYIFAGPRGTGKTTIARILAKVLNCLNPQEGEPCGKCENCV 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414  81 EIDEGRFVDYVEMDAASNRGVDEMAALLERAVYAPVDARFKVYMIDEVHMLTNHAFNAMLKTLEEPPPHVKFILATTDPQ 160
Cdd:PRK14953  81 EIDKGSFPDLIEIDAASNRGIDDIRALRDAVSYTPIKGKYKVYIIDEAHMLTKEAFNALLKTLEEPPPRTIFILCTTEYD 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414 161 KIPVTVLSRCLQFNLKQMPAGHIVSHLERILGEEQITFEPQALRLLARAAQGSMRDALSLTDQAIAYSANEVTESAVSGM 240
Cdd:PRK14953 161 KIPPTILSRCQRFIFSKPTKEQIKEYLKRICNEEKIEYEEKALDLLAQASEGGMRDAASLLDQASTYGEGKVTIKVVEEF 240
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414 241 LGALDQTYMVRLLDALAAANGPEILAIADEMSLRSLSFSTALQDLASLLHR--IAWAQFAPGSVLDEWPEAADLRRFAET 318
Cdd:PRK14953 241 LGIVSQESVRKFLNLLLESDVDEAIKFLRTLEEKGYNLNKFWKQLEEEIRNilLNKSLKNPEEVFQVEDFYRKLEKPLEA 320

                 .
gi 924601414 319 L 319
Cdd:PRK14953 321 L 321
PRK14957 PRK14957
DNA polymerase III subunits gamma and tau; Provisional
1-359 3.43e-108

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 184921 [Multi-domain]  Cd Length: 546  Bit Score: 341.68  E-value: 3.43e-108
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414   1 MTYQVLARKWRPKDFASLVGQEHVVRALTHALDGGRLHHAYLFTGTRGVGKTTLSRIFAKALNCETGVTSQPCGVCRACR 80
Cdd:PRK14957   1 MSYQALARKYRPQSFAEVAGQQHALNSLVHALETQKVHHAYLFTGTRGVGKTTLGRLLAKCLNCKTGVTAEPCNKCENCV 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414  81 EIDEGRFVDYVEMDAASNRGVDEMAALLERAVYAPVDARFKVYMIDEVHMLTNHAFNAMLKTLEEPPPHVKFILATTDPQ 160
Cdd:PRK14957  81 AINNNSFIDLIEIDAASRTGVEETKEILDNIQYMPSQGRYKVYLIDEVHMLSKQSFNALLKTLEEPPEYVKFILATTDYH 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414 161 KIPVTVLSRCLQFNLKQMPAGHIVSHLERILGEEQITFEPQALRLLARAAQGSMRDALSLTDQAIAYSANEVTESAVSGM 240
Cdd:PRK14957 161 KIPVTILSRCIQLHLKHISQADIKDQLKIILAKENINSDEQSLEYIAYHAKGSLRDALSLLDQAISFCGGELKQAQIKQM 240
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414 241 LGALDQTYMVRLLDALAAANGPEILAiademSLRSLSFSTALQDlaSLLHRIAWAQFApgSVLDEWPEAAD--------- 311
Cdd:PRK14957 241 LGIIDSEEVYSIINAIIDNDPKAILP-----AIKNLALTESSAD--AVLDRIAEIWFA--CCIYSFTQSLDavndidvdi 311
                        330       340       350       360
                 ....*....|....*....|....*....|....*....|....*...
gi 924601414 312 LRRFAETLSPEQVQLFYQIATVGRAELGLAPDEYAGFTMTLLRMLAFE 359
Cdd:PRK14957 312 INNILAKISIEQAHFLYQLTITAKKDIALAPNFETGVTMAILRLIAFQ 359
PRK14955 PRK14955
DNA polymerase III subunits gamma and tau; Provisional
1-373 3.24e-98

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 184919 [Multi-domain]  Cd Length: 397  Bit Score: 310.29  E-value: 3.24e-98
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414   1 MTYQVLARKWRPKDFASLVGQEHVVRALTHALDGGRLHHAYLFTGTRGVGKTTLSRIFAKALNCETGV--------TSQP 72
Cdd:PRK14955   1 MSYQVIARKYRPKKFADITAQEHITRTIQNSLRMGRVGHGYIFSGLRGVGKTTAARVFAKAVNCQRMIddadylqeVTEP 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414  73 CGVCRACREIDEGRFVDYVEMDAASNRGVDEMAALLERAVYAPVDARFKVYMIDEVHMLTNHAFNAMLKTLEEPPPHVKF 152
Cdd:PRK14955  81 CGECESCRDFDAGTSLNISEFDAASNNSVDDIRLLRENVRYGPQKGRYRVYIIDEVHMLSIAAFNAFLKTLEEPPPHAIF 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414 153 ILATTDPQKIPVTVLSRCLQFNLKQMPAGHIVSHLERILGEEQITFEPQALRLLARAAQGSMRDALSLTDQAIAYSANE- 231
Cdd:PRK14955 161 IFATTELHKIPATIASRCQRFNFKRIPLEEIQQQLQGICEAEGISVDADALQLIGRKAQGSMRDAQSILDQVIAFSVESe 240
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414 232 ----VTESAVSGMLGALDQTYMVRLLDALAAANGPEILAIADEMSLRSLSFSTALQDLASLLHRIAWAQFAPGSVLDEWP 307
Cdd:PRK14955 241 gegsIRYDKVAELLNYIDDEHFFAVTDAVADGDAVAMLDVAQFVIRNGYDEQDFLEKLIEHLRNFLVVHNLRSTRLVERP 320
                        330       340       350       360       370       380
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 924601414 308 EAADLR--RFAETLSPEQVQLFYQIATVGRAELGLAPDEYAGFTMTLLRMLAF-EPAVGAGSAPGGQPS 373
Cdd:PRK14955 321 DAVRERyeRDAAKFSPEVIMQMTDLLLQTQKELKFQFEYQFRFELALLKLIEIgHPAPTAAAAPTGGAQ 389
PRK14950 PRK14950
DNA polymerase III subunits gamma and tau; Provisional
1-507 4.98e-96

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237864 [Multi-domain]  Cd Length: 585  Bit Score: 310.97  E-value: 4.98e-96
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414   1 MTYQVLARKWRPKDFASLVGQEHVVRALTHALDGGRLHHAYLFTGTRGVGKTTLSRIFAKALNCETGVTS-QPCGVCRAC 79
Cdd:PRK14950   1 MTVQVLYRKWRSQTFAELVGQEHVVQTLRNAIAEGRVAHAYLFTGPRGVGKTSTARILAKAVNCTTNDPKgRPCGTCEMC 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414  80 REIDEGRFVDYVEMDAASNRGVDEMAALLERAVYAPVDARFKVYMIDEVHMLTNHAFNAMLKTLEEPPPHVKFILATTDP 159
Cdd:PRK14950  81 RAIAEGSAVDVIEMDAASHTSVDDAREIIERVQFRPALARYKVYIIDEVHMLSTAAFNALLKTLEEPPPHAIFILATTEV 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414 160 QKIPVTVLSRCLQFNLKQMPAGHIVSHLERILGEEQITFEPQALRLLARAAQGSMRDALSLTDQAIAYSANEVTESAVSG 239
Cdd:PRK14950 161 HKVPATILSRCQRFDFHRHSVADMAAHLRKIAAAEGINLEPGALEAIARAATGSMRDAENLLQQLATTYGGEISLSQVQS 240
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414 240 MLGALDQTYMVRLLDALAAANGPEilaiademslrslsfstALQDLASLLHriawaqfapgsvldewpEAADLRRFAETL 319
Cdd:PRK14950 241 LLGISGDEEVKALAEALLAKDLKA-----------------ALRTLNAVAA-----------------DGADLRQFTRDL 286
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414 320 SPEQVQLFYQIATVGRAELGLAPDEYA--GFTMTLLRMLAFEPAVGAGSAPGGQPSVPPRAVPAPRAAAAPTAAAAKPVS 397
Cdd:PRK14950 287 VEYLRQVMLLNSGADRSLLDLTADEKAalQKVSQIANLEALTKWVKAFSQLDFQLRTTSYGQLPLELAVIEALLVPVPAP 366
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414 398 ATpagaarpqaaapaapaapvarsapAQSSDEAERPAAKPPAVQSPAEAAAPIPAAADAQAIELPQPETKAAPAGDMPPP 477
Cdd:PRK14950 367 QP------------------------AKPTAAAPSPVRPTPAPSTRPKAAAAANIPPKEPVRETATPPPVPPRPVAPPVP 422
                        490       500       510
                 ....*....|....*....|....*....|
gi 924601414 478 TRKEPEPPAVAAVQRNDEPAPQAEPAPRAA 507
Cdd:PRK14950 423 HTPESAPKLTRAAIPVDEKPKYTPPAPPKE 452
PRK14948 PRK14948
DNA polymerase III subunit gamma/tau;
1-268 1.66e-94

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237862 [Multi-domain]  Cd Length: 620  Bit Score: 308.04  E-value: 1.66e-94
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414   1 MTYQVLARKWRPKDFASLVGQEHVVRALTHALDGGRLHHAYLFTGTRGVGKTTLSRIFAKALNC--ETGVTSQPCGVCRA 78
Cdd:PRK14948   1 MAYEPLHHKYRPQRFDELVGQEAIATTLKNALISNRIAPAYLFTGPRGTGKTSSARILAKSLNClnSDKPTPEPCGKCEL 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414  79 CREIDEGRFVDYVEMDAASNRGVDEMAALLERAVYAPVDARFKVYMIDEVHMLTNHAFNAMLKTLEEPPPHVKFILATTD 158
Cdd:PRK14948  81 CRAIAAGNALDVIEIDAASNTGVDNIRELIERAQFAPVQARWKVYVIDECHMLSTAAFNALLKTLEEPPPRVVFVLATTD 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414 159 PQKIPVTVLSRCLQFNLKQMPAGHIVSHLERILGEEQITFEPQALRLLARAAQGSMRDALSLTDQaIAYSANEVTESAVS 238
Cdd:PRK14948 161 PQRVLPTIISRCQRFDFRRIPLEAMVQHLSEIAEKESIEIEPEALTLVAQRSQGGLRDAESLLDQ-LSLLPGPITPEAVW 239
                        250       260       270
                 ....*....|....*....|....*....|
gi 924601414 239 GMLGALDQTYMVRLLDALAAANgPEILAIA 268
Cdd:PRK14948 240 DLLGAVPEQDLLNLLKALASND-PESLLDS 268
PRK14964 PRK14964
DNA polymerase III subunits gamma and tau; Provisional
6-270 1.75e-93

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237870 [Multi-domain]  Cd Length: 491  Bit Score: 301.32  E-value: 1.75e-93
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414   6 LARKWRPKDFASLVGQEHVVRALTHALDGGRLHHAYLFTGTRGVGKTTLSRIFAKALNCETGVTSQPCGVCRACREIDEG 85
Cdd:PRK14964   3 LALKYRPSSFKDLVGQDVLVRILRNAFTLNKIPQSILLVGASGVGKTTCARIISLCLNCSNGPTSDPCGTCHNCISIKNS 82
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414  86 RFVDYVEMDAASNRGVDEMAALLERAVYAPVDARFKVYMIDEVHMLTNHAFNAMLKTLEEPPPHVKFILATTDPQKIPVT 165
Cdd:PRK14964  83 NHPDVIEIDAASNTSVDDIKVILENSCYLPISSKFKVYIIDEVHMLSNSAFNALLKTLEEPAPHVKFILATTEVKKIPVT 162
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414 166 VLSRCLQFNLKQMPAGHIVSHLERILGEEQITFEPQALRLLARAAQGSMRDALSLTDQAIAYSANEVTESAVSGMLGALD 245
Cdd:PRK14964 163 IISRCQRFDLQKIPTDKLVEHLVDIAKKENIEHDEESLKLIAENSSGSMRNALFLLEQAAIYSNNKISEKSVRDLLGCVD 242
                        250       260
                 ....*....|....*....|....*
gi 924601414 246 QTYMVRLLDALAAANGPEILAIADE 270
Cdd:PRK14964 243 KHILEDLVEAILLGDAQSALNVFRE 267
PRK06305 PRK06305
DNA polymerase III subunits gamma and tau; Validated
2-291 3.21e-93

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 180523 [Multi-domain]  Cd Length: 451  Bit Score: 299.00  E-value: 3.21e-93
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414   2 TYQVLARKWRPKDFASLVGQEHVVRALTHALDGGRLHHAYLFTGTRGVGKTTLSRIFAKALNCETGVTSQ-PCGVCRACR 80
Cdd:PRK06305   3 SYQVSSRKYRPQTFSEILGQDAVVAVLKNALRFNRAAHAYLFSGIRGTGKTTLARIFAKALNCQNPTEDQePCNQCASCK 82
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414  81 EIDEGRFVDYVEMDAASNRGVDEMAALLERAVYAPVDARFKVYMIDEVHMLTNHAFNAMLKTLEEPPPHVKFILATTDPQ 160
Cdd:PRK06305  83 EISSGTSLDVLEIDGASHRGIEDIRQINETVLFTPSKSRYKIYIIDEVHMLTKEAFNSLLKTLEEPPQHVKFFLATTEIH 162
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414 161 KIPVTVLSRCLQFNLKQMPAGHIVSHLERILGEEQITFEPQALRLLARAAQGSMRDALSLTDQAIAYSANEVTESAVSGM 240
Cdd:PRK06305 163 KIPGTILSRCQKMHLKRIPEETIIDKLALIAKQEGIETSREALLPIARAAQGSLRDAESLYDYVVGLFPKSLDPDSVAKA 242
                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|.
gi 924601414 241 LGALDQTYMVRLLDALAAANGPEILAIADEMSLRSLSFSTALQDLaSLLHR 291
Cdd:PRK06305 243 LGLLSQDSLYTLDEAITTQNYAQALEPVTDAMNSGVAPAHFLHDL-TLFFR 292
PRK14962 PRK14962
DNA polymerase III subunits gamma and tau; Provisional
4-285 3.89e-93

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237869 [Multi-domain]  Cd Length: 472  Bit Score: 299.76  E-value: 3.89e-93
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414   4 QVLARKWRPKDFASLVGQEHVVRALTHALDGGRLHHAYLFTGTRGVGKTTLSRIFAKALNCETGVTSQPCGVCRACREID 83
Cdd:PRK14962   2 EALYRKYRPKTFSEVVGQDHVKKLIINALKKNSISHAYIFAGPRGTGKTTVARILAKSLNCENRKGVEPCNECRACRSID 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414  84 EGRFVDYVEMDAASNRGVDEMAALLERAVYAPVDARFKVYMIDEVHMLTNHAFNAMLKTLEEPPPHVKFILATTDPQKIP 163
Cdd:PRK14962  82 EGTFMDVIELDAASNRGIDEIRKIRDAVGYRPMEGKYKVYIIDEVHMLTKEAFNALLKTLEEPPSHVVFVLATTNLEKVP 161
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414 164 VTVLSRCLQFNLKQMPAGHIVSHLERILGEEQITFEPQALRLLARAAQGSMRDALSLTDQAIAYSANEVTESAVSGMLGA 243
Cdd:PRK14962 162 PTIISRCQVIEFRNISDELIIKRLQEVAEAEGIEIDREALSFIAKRASGGLRDALTMLEQVWKFSEGKITLETVHEALGL 241
                        250       260       270       280
                 ....*....|....*....|....*....|....*....|..
gi 924601414 244 LDQTYMVRLLDALAAANGPEILAIADEMSLRSLSFSTALQDL 285
Cdd:PRK14962 242 IPIEVVRDYINAIFNGDVKRVFTVLDDVYYSGKDYEVLIQQA 283
PRK06647 PRK06647
DNA polymerase III subunits gamma and tau; Validated
1-286 1.07e-91

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 235845 [Multi-domain]  Cd Length: 563  Bit Score: 298.61  E-value: 1.07e-91
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414   1 MTYQVLARKWRPKDFASLVGQEHVVRALTHALDGGRLHHAYLFTGTRGVGKTTLSRIFAKALNCETGVTSQPCGVCRACR 80
Cdd:PRK06647   1 MSYRGTATKRRPRDFNSLEGQDFVVETLKHSIESNKIANAYIFSGPRGVGKTSSARAFARCLNCVNGPTPMPCGECSSCK 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414  81 EIDEGRFVDYVEMDAASNRGVDEMAALLERAVYAPVDARFKVYMIDEVHMLTNHAFNAMLKTLEEPPPHVKFILATTDPQ 160
Cdd:PRK06647  81 SIDNDNSLDVIEIDGASNTSVQDVRQIKEEIMFPPASSRYRVYIIDEVHMLSNSAFNALLKTIEEPPPYIVFIFATTEVH 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414 161 KIPVTVLSRCLQFNLKQMPAGHIVSHLERILGEEQITFEPQALRLLARAAQGSMRDALSLTDQAIAYSANEVTESAVSGM 240
Cdd:PRK06647 161 KLPATIKSRCQHFNFRLLSLEKIYNMLKKVCLEDQIKYEDEALKWIAYKSTGSVRDAYTLFDQVVSFSDSDITLEQIRSK 240
                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*.
gi 924601414 241 LGALDQTYMVRLLDALAAANGPEILAIADEMSLRSLSFSTALQDLA 286
Cdd:PRK06647 241 MGLTGDEFLEKLASSILNEDAKELLCVLDSVFLSGVSVEQFLLDCI 286
PRK07133 PRK07133
DNA polymerase III subunits gamma and tau; Validated
1-289 2.09e-91

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 235943 [Multi-domain]  Cd Length: 725  Bit Score: 302.51  E-value: 2.09e-91
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414   1 MTYQVLARKWRPKDFASLVGQEHVVRALTHALDGGRLHHAYLFTGTRGVGKTTLSRIFAKALNCE-TGVTSQPCGVCRAc 79
Cdd:PRK07133   3 MKYKALYRKYRPKTFDDIVGQDHIVQTLKNIIKSNKISHAYLFSGPRGTGKTSVAKIFANALNCShKTDLLEPCQECIE- 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414  80 rEIDegRFVDYVEMDAASNRGVDEMAALLERAVYAPVDARFKVYMIDEVHMLTNHAFNAMLKTLEEPPPHVKFILATTDP 159
Cdd:PRK07133  82 -NVN--NSLDIIEMDAASNNGVDEIRELIENVKNLPTQSKYKIYIIDEVHMLSKSAFNALLKTLEEPPKHVIFILATTEV 158
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414 160 QKIPVTVLSRCLQFNLKQMPAGHIVSHLERILGEEQITFEPQALRLLARAAQGSMRDALSLTDQAIAYSANEVTESAVSG 239
Cdd:PRK07133 159 HKIPLTILSRVQRFNFRRISEDEIVSRLEFILEKENISYEKNALKLIAKLSSGSLRDALSIAEQVSIFGNNKITLKNVEE 238
                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|
gi 924601414 240 MLGALDQTYMVRLLDALAAANGPEILAIADEMSLRSLSFSTALQDLASLL 289
Cdd:PRK07133 239 LFGLVSNENLINLLNLLYSKDIKEVLNILNQIKEQGIDPELLLISLINLV 288
PRK14971 PRK14971
DNA polymerase III subunit gamma/tau;
3-271 8.01e-88

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237874 [Multi-domain]  Cd Length: 614  Bit Score: 290.14  E-value: 8.01e-88
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414   3 YQVLARKWRPKDFASLVGQEHVVRALTHALDGGRLHHAYLFTGTRGVGKTTLSRIFAKALNCET-GVTSQPCGVCRACRE 81
Cdd:PRK14971   4 YIVSARKYRPSTFESVVGQEALTTTLKNAIATNKLAHAYLFCGPRGVGKTTCARIFAKTINCQNlTADGEACNECESCVA 83
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414  82 IDEGRFVDYVEMDAASNRGVDEMAALLERAVYAPVDARFKVYMIDEVHMLTNHAFNAMLKTLEEPPPHVKFILATTDPQK 161
Cdd:PRK14971  84 FNEQRSYNIHELDAASNNSVDDIRNLIEQVRIPPQIGKYKIYIIDEVHMLSQAAFNAFLKTLEEPPSYAIFILATTEKHK 163
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414 162 IPVTVLSRCLQFNLKQMPAGHIVSHLERILGEEQITFEPQALRLLARAAQGSMRDALSLTDQAIAYSANEVTESAVSGML 241
Cdd:PRK14971 164 ILPTILSRCQIFDFNRIQVADIVNHLQYVASKEGITAEPEALNVIAQKADGGMRDALSIFDQVVSFTGGNITYKSVIENL 243
                        250       260       270
                 ....*....|....*....|....*....|
gi 924601414 242 GALDQTYMVRLLDALAAANGPEILAIADEM 271
Cdd:PRK14971 244 NILDYDYYFRLTDALLAGKVSDSLLLFDEI 273
PRK14954 PRK14954
DNA polymerase III subunits gamma and tau; Provisional
1-508 2.17e-87

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 184918 [Multi-domain]  Cd Length: 620  Bit Score: 289.15  E-value: 2.17e-87
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414   1 MTYQVLARKWRPKDFASLVGQEHVVRALTHALDGGRLHHAYLFTGTRGVGKTTLSRIFAKALNCETGV--------TSQP 72
Cdd:PRK14954   1 MSYQVIARKYRPSKFADITAQEHITHTIQNSLRMDRVGHGYIFSGLRGVGKTTAARVFAKAVNCQRMIddpvylqeVTEP 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414  73 CGVCRACREIDEGRFVDYVEMDAASNRGVDEMAALLERAVYAPVDARFKVYMIDEVHMLTNHAFNAMLKTLEEPPPHVKF 152
Cdd:PRK14954  81 CGECESCRDFDAGTSLNISEFDAASNNSVDDIRQLRENVRYGPQKGRYRVYIIDEVHMLSTAAFNAFLKTLEEPPPHAIF 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414 153 ILATTDPQKIPVTVLSRCLQFNLKQMPAGHIVSHLERILGEEQITFEPQALRLLARAAQGSMRDALSLTDQAIAYSANEV 232
Cdd:PRK14954 161 IFATTELHKIPATIASRCQRFNFKRIPLDEIQSQLQMICRAEGIQIDADALQLIARKAQGSMRDAQSILDQVIAFSVGSE 240
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414 233 TESA-----VSGMLGALDQTYMVRLLDALAAANGPEILAIADEMSLRSLSFSTALQDLASLLHRIAWAQFAPGSVLDEWP 307
Cdd:PRK14954 241 AEKViayqgVAELLNYIDDEQFFDVTDAIAENDAVKMLEVARFVIDNGYDEQDFLEKLIEHFRNFLVLYNLRSTRLIERP 320
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414 308 EAADLR--RFAETLSPEQVQLFYQIATVGRAELGLAPDEYAGFTMTLLRMLAF-EPAVGAGSAPGGQPSVPPRAVPAPRA 384
Cdd:PRK14954 321 ESVKERyqQSAGGLTPAAVMQMTDFLMKTQGELKFQFEYQFRFELALLRLIELvRNDGGVAPSPAGSPDVKKKAPEPDLP 400
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414 385 AAAPTAAAAKPvsatpagaarpqaaapaapaapvarsapaqssdeaERPAAKPpavqspaeaaapipaaadaqaIELPQP 464
Cdd:PRK14954 401 QPDRHPGPAKP-----------------------------------EAPGARP---------------------AELPSP 424
                        490       500       510       520
                 ....*....|....*....|....*....|....*....|....
gi 924601414 465 ETKAAPAGdMPPPTRKEPEPpavaavqrndePAPQAEPAPRAAS 508
Cdd:PRK14954 425 ASAPTPEQ-QPPVARSAPLP-----------PSPQASAPRNVAS 456
PRK14959 PRK14959
DNA polymerase III subunits gamma and tau; Provisional
1-370 2.82e-85

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 184923 [Multi-domain]  Cd Length: 624  Bit Score: 283.49  E-value: 2.82e-85
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414   1 MTYQVLARKWRPKDFASLVGQEHVVRALTHALDGGRLHHAYLFTGTRGVGKTTLSRIFAKALNCETGVTSQPCGVCRACR 80
Cdd:PRK14959   1 MSHASLTARYRPQTFAEVAGQETVKAILSRAAQENRVAPAYLFSGTRGVGKTTIARIFAKALNCETAPTGEPCNTCEQCR 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414  81 EIDEGRFVDYVEMDAASNRGVDEMAALLERAVYAPVDARFKVYMIDEVHMLTNHAFNAMLKTLEEPPPHVKFILATTDPQ 160
Cdd:PRK14959  81 KVTQGMHVDVVEIDGASNRGIDDAKRLKEAIGYAPMEGRYKVFIIDEAHMLTREAFNALLKTLEEPPARVTFVLATTEPH 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414 161 KIPVTVLSRCLQFNLKQMPAGHIVSHLERILGEEQITFEPQALRLLARAAQGSMRDALSLTDQAIAYSANEVTESAVSGM 240
Cdd:PRK14959 161 KFPVTIVSRCQHFTFTRLSEAGLEAHLTKVLGREGVDYDPAAVRLIARRAAGSVRDSMSLLGQVLALGESRLTIDGARGV 240
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414 241 LGALDQTYMVRLLDALAAANGPEILAIADEMSLRSLSFSTALQDLAS------LLHRIAWAQFAPGSVLDEwpEAADLRR 314
Cdd:PRK14959 241 LGLAGQELFLRLMEALAAQDCLGVANVVRELLDRGVDMGFFLRELVAtwrnlfMLRQAGEAALASLDLPED--EARQWLG 318
                        330       340       350       360       370       380
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 924601414 315 FAETLSPEQVQLFYQIATVGRAELGLAPDEYAGFTMTLL------RMLAFE---PAVGAGSAPGG 370
Cdd:PRK14959 319 WAKRFEPAHIHACWQMTLEGQRRVLTSLEPAMALELLLLnlamlpRLMPVEslrPSGGGASAPSG 383
PRK05896 PRK05896
DNA polymerase III subunits gamma and tau; Validated
1-289 3.58e-79

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 235638 [Multi-domain]  Cd Length: 605  Bit Score: 266.71  E-value: 3.58e-79
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414   1 MTYQVLARKWRPKDFASLVGQEHVVRALTHALDGGRLHHAYLFTGTRGVGKTTLSRIFAKALNCETGVTSQPCGVCRACR 80
Cdd:PRK05896   1 MSEITFYRKYRPHNFKQIIGQELIKKILVNAILNNKLTHAYIFSGPRGIGKTSIAKIFAKAINCLNPKDGDCCNSCSVCE 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414  81 EIDEGRFVDYVEMDAASNRGVDEMAALLERAVYAPVDARFKVYMIDEVHMLTNHAFNAMLKTLEEPPPHVKFILATTDPQ 160
Cdd:PRK05896  81 SINTNQSVDIVELDAASNNGVDEIRNIIDNINYLPTTFKYKVYIIDEAHMLSTSAWNALLKTLEEPPKHVVFIFATTEFQ 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414 161 KIPVTVLSRCLQFNLKQMPAGHIVSHLERILGEEQITFEPQALRLLARAAQGSMRDALSLTDQAIAYSANEVTESAVSGM 240
Cdd:PRK05896 161 KIPLTIISRCQRYNFKKLNNSELQELLKSIAKKEKIKIEDNAIDKIADLADGSLRDGLSILDQLSTFKNSEIDIEDINKT 240
                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*....
gi 924601414 241 LGALDQTYMVRLLDALAAANGPEILAIADEMSLRSLSFSTALQDLASLL 289
Cdd:PRK05896 241 FGLVDNNKKINLIELIQKNDIEELRNLINELESKGINFEAFCRDLINLL 289
PRK06645 PRK06645
DNA polymerase III subunits gamma and tau; Validated
3-354 1.58e-77

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 180643 [Multi-domain]  Cd Length: 507  Bit Score: 259.41  E-value: 1.58e-77
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414   3 YQVLARKWRPKDFASLVGQEHVVRALTHALDGGRLHHAYLFTGTRGVGKTTLSRIFAKALNCETGVTS----QPCGVCRA 78
Cdd:PRK06645   8 YIPFARKYRPSNFAELQGQEVLVKVLSYTILNDRLAGGYLLTGIRGVGKTTSARIIAKAVNCSALITEnttiKTCEQCTN 87
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414  79 CREIDEGRFVDYVEMDAASNRGVDEMAALLERAVYAPVDARFKVYMIDEVHMLTNHAFNAMLKTLEEPPPHVKFILATTD 158
Cdd:PRK06645  88 CISFNNHNHPDIIEIDAASKTSVDDIRRIIESAEYKPLQGKHKIFIIDEVHMLSKGAFNALLKTLEEPPPHIIFIFATTE 167
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414 159 PQKIPVTVLSRCLQFNLKQMPAGHIVSHLERILGEEQITFEPQALRLLARAAQGSMRDALSLTDQAIAYSANE---VTES 235
Cdd:PRK06645 168 VQKIPATIISRCQRYDLRRLSFEEIFKLLEYITKQENLKTDIEALRIIAYKSEGSARDAVSILDQAASMSAKSdniISPQ 247
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414 236 AVSGMLGALDQTYMVRLLDALAAANGPEILAIADEMSLRSLSFSTALQDLASLLHRIAWAQFAPGSVLDEWPEAAD-LRR 314
Cdd:PRK06645 248 VINQMLGLVDSSVIIEFVEYIIHRETEKAINLINKLYGSSVNLEIFIESVSDFIAYLNKVKMLPNYSLPIYESFNDrTKS 327
                        330       340       350       360
                 ....*....|....*....|....*....|....*....|
gi 924601414 315 FAETLSPEQVQLFYQIATVGRAELGLAPDEYAGFTMTLLR 354
Cdd:PRK06645 328 ILDKISLPHLSILWQIYNKGVGEIKISYNQLTETEMLVIK 367
PRK14956 PRK14956
DNA polymerase III subunits gamma and tau; Provisional
2-290 8.42e-77

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 184920 [Multi-domain]  Cd Length: 484  Bit Score: 256.80  E-value: 8.42e-77
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414   2 TYQVLARKWRPKDFASLVGQEHVVRALTHALDGGRLHHAYLFTGTRGVGKTTLSRIFAKALNCETGVTSQPCGVCRACRE 81
Cdd:PRK14956   4 THEVLSRKYRPQFFRDVIHQDLAIGALQNALKSGKIGHAYIFFGPRGVGKTTIARILAKRLNCENPIGNEPCNECTSCLE 83
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414  82 IDEGRFVDYVEMDAASNRGVDEMAALLERAVYAPVDARFKVYMIDEVHMLTNHAFNAMLKTLEEPPPHVKFILATTDPQK 161
Cdd:PRK14956  84 ITKGISSDVLEIDAASNRGIENIRELRDNVKFAPMGGKYKVYIIDEVHMLTDQSFNALLKTLEEPPAHIVFILATTEFHK 163
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414 162 IPVTVLSRCLQFNLKQMPAGHIVSHLERILGEEQITFEPQALRLLARAAQGSMRDALSLTDQAIAYSANEVTESAVSGML 241
Cdd:PRK14956 164 IPETILSRCQDFIFKKVPLSVLQDYSEKLCKIENVQYDQEGLFWIAKKGDGSVRDMLSFMEQAIVFTDSKLTGVKIRKMI 243
                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|
gi 924601414 242 GALDQTYMVRLLDALA-AANGPEILAIADEMSLRSLSFSTALQDLASLLH 290
Cdd:PRK14956 244 GYHGIEFLTSFIKSLIdPDNHSKSLEILESLYQEGQDIYKFLWDSIEFTH 293
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
6-508 3.26e-72

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 252.60  E-value: 3.26e-72
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414   6 LARKWRPKDFASLVGQEHVVRALTHALDGGRLHHAYLFTGTRGVGKTTLSRIFAKALNCETGVTSQPCGVCRACREI--D 83
Cdd:PRK07764   5 LYRRYRPATFAEVIGQEHVTEPLSTALDSGRINHAYLFSGPRGCGKTSSARILARSLNCVEGPTSTPCGECDSCVALapG 84
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414  84 EGRFVDYVEMDAASNRGVDEMAALLERAVYAPVDARFKVYMIDEVHMLTNHAFNAMLKTLEEPPPHVKFILATTDPQKIP 163
Cdd:PRK07764  85 GPGSLDVTEIDAASHGGVDDARELRERAFFAPAESRYKIFIIDEAHMVTPQGFNALLKIVEEPPEHLKFIFATTEPDKVI 164
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414 164 VTVLSRCLQFNLKQMPAGHIVSHLERILGEEQITFEPQALRLLARAAQGSMRDALSLTDQAIAYSANE-VT-ESAVSgML 241
Cdd:PRK07764 165 GTIRSRTHHYPFRLVPPEVMRGYLERICAQEGVPVEPGVLPLVIRAGGGSVRDSLSVLDQLLAGAGPEgVTyERAVA-LL 243
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414 242 GALDQTYMVRLLDALAAANGPEILAIADEMS----------------LRSLSFSTALQDLASllhriawaqfapgSVLDE 305
Cdd:PRK07764 244 GVTDSALIDEAVDALAAGDGAALFGTVDRVIeaghdprrfaedllerLRDLIVLQAVPDAAE-------------RGLVD 310
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414 306 WPE--AADLRRFAETLSPEQVQLFYQI----------AT---------VGRAELGLAPDEYAGFTMTLLRMLAFEPAVGA 364
Cdd:PRK07764 311 APAdqLDRMRAQAQRLGPAELTRAADVvndgltemrgATsprlllellCARMLLPSASDDERGLLARLERLERRLGVAGG 390
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414 365 GSAPGGQPSVPPRAVPAPRAAAAPTAAAAKPVSATPAgaarpqaaapaapaapvarsapaqssdeAERPAAKPPAVQSPA 444
Cdd:PRK07764 391 AGAPAAAAPSAAAAAPAAAPAPAAAAPAAAAAPAPAA----------------------------APQPAPAPAPAPAPP 442
                        490       500       510       520       530       540
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 924601414 445 EAAAPIPAAADAQAIELPQPETKAAPAGDMPPPTRKEPEPPAVAAVQRNDEPAPQAEPAPRAAS 508
Cdd:PRK07764 443 SPAGNAPAGGAPSPPPAAAPSAQPAPAPAAAPEPTAAPAPAPPAAPAPAAAPAAPAAPAAPAGA 506
PRK14970 PRK14970
DNA polymerase III subunits gamma and tau; Provisional
5-271 1.58e-69

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 184934 [Multi-domain]  Cd Length: 367  Bit Score: 233.23  E-value: 1.58e-69
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414   5 VLARKWRPKDFASLVGQEHVVRALTHALDGGRLHHAYLFTGTRGVGKTTLSRIFAKALNCETGVTSqpcgvcracreiDE 84
Cdd:PRK14970   6 VSARKYRPQTFDDVVGQSHITNTLLNAIENNHLAQALLFCGPRGVGKTTCARILARKINQPGYDDP------------NE 73
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414  85 GRFVDYVEMDAASNRGVDEMAALLERAVYAPVDARFKVYMIDEVHMLTNHAFNAMLKTLEEPPPHVKFILATTDPQKIPV 164
Cdd:PRK14970  74 DFSFNIFELDAASNNSVDDIRNLIDQVRIPPQTGKYKIYIIDEVHMLSSAAFNAFLKTLEEPPAHAIFILATTEKHKIIP 153
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414 165 TVLSRCLQFNLKQMPAGHIVSHLERILGEEQITFEPQALRLLARAAQGSMRDALSLTDQAIAYSANEVTESAVSGMLGAL 244
Cdd:PRK14970 154 TILSRCQIFDFKRITIKDIKEHLAGIAVKEGIKFEDDALHIIAQKADGALRDALSIFDRVVTFCGKNITRQAVTENLNIL 233
                        250       260
                 ....*....|....*....|....*..
gi 924601414 245 DQTYMVRLLDALAAANGPEILAIADEM 271
Cdd:PRK14970 234 DYDTYINVTDLILENKIPELLLAFNEI 260
PRK14952 PRK14952
DNA polymerase III subunits gamma/tau;
4-261 8.08e-69

DNA polymerase III subunits gamma/tau;


Pssm-ID: 237866 [Multi-domain]  Cd Length: 584  Bit Score: 237.86  E-value: 8.08e-69
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414   4 QVLARKWRPKDFASLVGQEHVVRALTHALDGGRLHHAYLFTGTRGVGKTTLSRIFAKALNCETGVTSQPCGVCRACreID 83
Cdd:PRK14952   1 MALYRKYRPATFAEVVGQEHVTEPLSSALDAGRINHAYLFSGPRGCGKTSSARILARSLNCAQGPTATPCGVCESC--VA 78
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414  84 EGR----FVDYVEMDAASNRGVDEMAALLERAVYAPVDARFKVYMIDEVHMLTNHAFNAMLKTLEEPPPHVKFILATTDP 159
Cdd:PRK14952  79 LAPngpgSIDVVELDAASHGGVDDTRELRDRAFYAPAQSRYRIFIVDEAHMVTTAGFNALLKIVEEPPEHLIFIFATTEP 158
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414 160 QKIPVTVLSRCLQFNLKQMPAGHIVSHLERILGEEQITFEPQALRLLARAAQGSMRDALSLTDQAIAYSANE-VTESAVS 238
Cdd:PRK14952 159 EKVLPTIRSRTHHYPFRLLPPRTMRALIARICEQEGVVVDDAVYPLVIRAGGGSPRDTLSVLDQLLAGAADThVTYQRAL 238
                        250       260
                 ....*....|....*....|...
gi 924601414 239 GMLGALDQTYMVRLLDALAAANG 261
Cdd:PRK14952 239 GLLGATDVALIDDAVDALAADDA 261
PRK14963 PRK14963
DNA polymerase III subunits gamma and tau; Provisional
6-300 1.32e-68

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 184927 [Multi-domain]  Cd Length: 504  Bit Score: 235.12  E-value: 1.32e-68
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414   6 LARKWRPKDFASLVGQEHVVRALTHALDGGRLHHAYLFTGTRGVGKTTLSRIFAKALNCeTGVTSQPCGVCRACREIDEG 85
Cdd:PRK14963   4 LYQRARPITFDEVVGQEHVKEVLLAALRQGRLGHAYLFSGPRGVGKTTTARLIAMAVNC-SGEDPKPCGECESCLAVRRG 82
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414  86 RFVDYVEMDAASNRGVDEMAALLERAVYAPVDARFKVYMIDEVHMLTNHAFNAMLKTLEEPPPHVKFILATTDPQKIPVT 165
Cdd:PRK14963  83 AHPDVLEIDAASNNSVEDVRDLREKVLLAPLRGGRKVYILDEAHMMSKSAFNALLKTLEEPPEHVIFILATTEPEKMPPT 162
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414 166 VLSRCLQFNLKQMPAGHIVSHLERILGEEQITFEPQALRLLARAAQGSMRDALSLTDQAIAYSAnEVTESAVSGMLGALD 245
Cdd:PRK14963 163 ILSRTQHFRFRRLTEEEIAGKLRRLLEAEGREAEPEALQLVARLADGAMRDAESLLERLLALGT-PVTRKQVEEALGLPP 241
                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 924601414 246 QTYMVRLLDALAAANGPEILAIADEMSLRSLSFSTALQDLASLLHRIAWAQFAPG 300
Cdd:PRK14963 242 QERLRGIAAALAQGDAAEALSGAAQLYRDGFAARTLVEGLLEAFRAALYAELGLG 296
HolB COG0470
DNA polymerase III, delta prime subunit [Replication, recombination and repair];
21-305 1.22e-52

DNA polymerase III, delta prime subunit [Replication, recombination and repair];


Pssm-ID: 440238 [Multi-domain]  Cd Length: 289  Bit Score: 184.79  E-value: 1.22e-52
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414  21 QEHVVRALTHALDGGRLHHAYLFTGTRGVGKTTLSRIFAKALNCETGVTSQPCGVCRaCREIDEGRFVDYVEM---DAAS 97
Cdd:COG0470    1 QEEAWEQLLAAAESGRLPHALLLHGPPGIGKTTLALALARDLLCENPEGGKACGQCH-SRLMAAGNHPDLLELnpeEKSD 79
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414  98 NRGVDEMAALLERAVYAPVDARFKVYMIDEVHMLTNHAFNAMLKTLEEPPPHVKFILATTDPQKIPVTVLSRCLQFNLKQ 177
Cdd:COG0470   80 QIGIDQIRELGEFLSLTPLEGGRKVVIIDEADAMNEAAANALLKTLEEPPKNTPFILIANDPSRLLPTIRSRCQVIRFRP 159
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414 178 MPAGHIVSHLErilgEEQItfEPQALRLLARAAQGSMRDALSLTDQAIAYSAnevtesAVSGMLGALDQTYMVRLLDALA 257
Cdd:COG0470  160 PSEEEALAWLR----EEGV--DEDALEAILRLAGGDPRAAINLLQALAGRKE------LLEDLAALLSRDRALELLDALL 227
                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*...
gi 924601414 258 AANGPEILAIADEMSLRSLSFSTALQDLASLLHRIAWAQFAPGSVLDE 305
Cdd:COG0470  228 KAEALELLDWLLKWLLDNLPLEYAGEDLARAYEALSEADRRLGRYAND 275
holB TIGR00678
DNA polymerase III, delta' subunit; This model describes the N-terminal half of the delta' ...
26-213 1.14e-46

DNA polymerase III, delta' subunit; This model describes the N-terminal half of the delta' subunit of DNA polymerase III. Delta' is homologous to the gamma and tau subunits, which form an outgroup for phylogenetic comparison. The gamma/tau branch of the tree is much more tighly conserved than the delta' branch, and some members of that branch score more highly against this model than some proteins classisified as delta'. The noise cutoff is set to detect weakly scoring delta' subunits rather than to exclude gamma/tau subunits. At position 126-127 of the seed alignment, this family lacks the HM motif of gamma/tau; at 132 it has a near-invariant A vs. an invariant F in gamma/tau. [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 273213 [Multi-domain]  Cd Length: 188  Bit Score: 164.34  E-value: 1.14e-46
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414   26 RALTHALDGGRLHHAYLFTGTRGVGKTTLSRIFAKALNCETGVTSQPCGVCRACREIDEGRFVDYVEMDAASNR-GVDEM 104
Cdd:TIGR00678   2 QQLKRALEKGRLAHAYLFTGPEGVGKELLALALAKALLCEQRGGGEPCGECHSCRLIEAGNHPDLHRLEPEGQSiKVDQV 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414  105 AALLERAVYAPVDARFKVYMIDEVHMLTNHAFNAMLKTLEEPPPHVKFILATTDPQKIPVTVLSRCLQFNLKQMPAghiv 184
Cdd:TIGR00678  82 RELVEFLSRTPQESGRRVVIIEDAERMNEAAANALLKTLEEPPPNTLFILITPSPEKLLPTIRSRCQRLPFPPLSE---- 157
                         170       180
                  ....*....|....*....|....*....
gi 924601414  185 SHLERILGEEQItfEPQALRLLARAAQGS 213
Cdd:TIGR00678 158 EALLQWLIRQGI--SEEAAELLLALAGGS 184
DNA_pol3_delta2 pfam13177
DNA polymerase III, delta subunit; DNA polymerase III, delta subunit (EC 2.7.7.7) is required ...
20-179 8.01e-46

DNA polymerase III, delta subunit; DNA polymerase III, delta subunit (EC 2.7.7.7) is required for, along with delta' subunit, the assembly of the processivity factor beta(2) onto primed DNA in the DNA polymerase III holoenzyme-catalyzed reaction. The delta subunit is also known as HolA.


Pssm-ID: 433013 [Multi-domain]  Cd Length: 161  Bit Score: 161.22  E-value: 8.01e-46
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414   20 GQEHVVRALTHALDGGRLHHAYLFTGTRGVGKTTLSRIFAKALNCETGVTSQPCGVCRACREIDEGRFVD--YVEMDAAS 97
Cdd:pfam13177   1 GQPEAIQLLQNSLENGRLSHAYLFSGPEGVGKLELALAFAKALFCEEPGDDLPCGQCRSCRRIESGNHPDlvIIEPEGQS 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414   98 NRgVDEMAALLERAVYAPVDARFKVYMIDEVHMLTNHAFNAMLKTLEEPPPHVKFILATTDPQKIPVTVLSRCLQFNLKQ 177
Cdd:pfam13177  81 IK-IDQIRELQKEFSKSPYEGKKKVYIIEDAEKMTASAANSLLKFLEEPPGNTVIILLTENPSRLLPTIRSRCQIIRFKP 159

                  ..
gi 924601414  178 MP 179
Cdd:pfam13177 160 LS 161
PRK08058 PRK08058
DNA polymerase III subunit delta'; Validated
21-220 1.78e-31

DNA polymerase III subunit delta'; Validated


Pssm-ID: 181214 [Multi-domain]  Cd Length: 329  Bit Score: 125.81  E-value: 1.78e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414  21 QEHVVRALTHALDGGRLHHAYLFTGTRGVGKTTLSRIFAKALNCETGVTSQPCGVCRACREIDEGRFVD--YVEMDAASN 98
Cdd:PRK08058  11 QPVVVKMLQNSIAKNRLSHAYLFEGAKGTGKKATALWLAKSLFCLERNGVEPCGTCTNCKRIDSGNHPDvhLVAPDGQSI 90
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414  99 RgVDEMAALLERAVYAPVDARFKVYMIDEVHMLTNHAFNAMLKTLEEPPPHVKFILATTDPQKIPVTVLSRCLQFNLKQM 178
Cdd:PRK08058  91 K-KDQIRYLKEEFSKSGVESNKKVYIIEHADKMTASAANSLLKFLEEPSGGTTAILLTENKHQILPTILSRCQVVEFRPL 169
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|..
gi 924601414 179 PAGHIVSHLErilgEEQItfePQALRLLARAAQGSMRDALSL 220
Cdd:PRK08058 170 PPESLIQRLQ----EEGI---SESLATLLAGLTNSVEEALAL 204
PRK07940 PRK07940
DNA polymerase III subunit delta'; Validated
15-212 9.61e-30

DNA polymerase III subunit delta'; Validated


Pssm-ID: 236134 [Multi-domain]  Cd Length: 394  Bit Score: 122.33  E-value: 9.61e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414  15 FASLVGQEHVVRALTHALDGGRLH---------HAYLFTGTRGVGKTTLSRIFAKALNCeTGVTSQPCGVCRACREIDEG 85
Cdd:PRK07940   4 WDDLVGQEAVVAELRAAARAARADvaaagsgmtHAWLFTGPPGSGRSVAARAFAAALQC-TDPDEPGCGECRACRTVLAG 82
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414  86 RFVD--YVEMDAASnRGVDEMAALLERAVYAPVDARFKVYMIDEVHMLTNHAFNAMLKTLEEPPPHVKFILATTDPQKIP 163
Cdd:PRK07940  83 THPDvrVVAPEGLS-IGVDEVRELVTIAARRPSTGRWRIVVIEDADRLTERAANALLKAVEEPPPRTVWLLCAPSPEDVL 161
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*....
gi 924601414 164 VTVLSRCLQFNLKQMPAGHIVSHLERILGeeqitFEPQALRLLARAAQG 212
Cdd:PRK07940 162 PTIRSRCRHVALRTPSVEAVAEVLVRRDG-----VDPETARRAARASQG 205
PRK12402 PRK12402
replication factor C small subunit 2; Reviewed
9-271 1.19e-27

replication factor C small subunit 2; Reviewed


Pssm-ID: 237090 [Multi-domain]  Cd Length: 337  Bit Score: 114.70  E-value: 1.19e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414   9 KWRPKDFASLVGQEHVVRALTHALDGGRLHHaYLFTGTRGVGKTTLSRIFAKAL---NCETGVTSQPCGVC--RACREID 83
Cdd:PRK12402   8 KYRPALLEDILGQDEVVERLSRAVDSPNLPH-LLVQGPPGSGKTAAVRALARELygdPWENNFTEFNVADFfdQGKKYLV 86
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414  84 EG-RFVDYVEMDAASNRGVDEM--AALLERAVYAPVDARFKVYMIDEVHMLTNHAFNAMLKTLEEPPPHVKFILATTDPQ 160
Cdd:PRK12402  87 EDpRFAHFLGTDKRIRSSKIDNfkHVLKEYASYRPLSADYKTILLDNAEALREDAQQALRRIMEQYSRTCRFIIATRQPS 166
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414 161 KIPVTVLSRCLQFNLKQMPAGHIVSHLERILGEEQITFEPQALRLLARAAQGSMRDALsLTDQAIAYSANEVTESAVSGM 240
Cdd:PRK12402 167 KLIPPIRSRCLPLFFRAPTDDELVDVLESIAEAEGVDYDDDGLELIAYYAGGDLRKAI-LTLQTAALAAGEITMEAAYEA 245
                        250       260       270
                 ....*....|....*....|....*....|..
gi 924601414 241 LGALDQTYMVR-LLDALAAANGPEILAIADEM 271
Cdd:PRK12402 246 LGDVGTDEVIEsLLDAAEAGDFTDARKTLDDL 277
HLD_clamp_pol_III_gamma_tau cd18137
helical lid domain of DNA polymerase III subunits gamma and tau; DNA polymerase III subunit ...
178-242 1.16e-24

helical lid domain of DNA polymerase III subunits gamma and tau; DNA polymerase III subunit gamma/tau is part of the DNA polymerase III holoenzyme. Gamma and tau subunits are isoforms, both containing the helical lid domain. Gamma interacts with the delta subunit to transfer the beta subunit on the DNA while tau serves as a scaffold to help in the dimerization of the core complex. Both are members of the clamp-loader clade of the AAA+ superfamily.


Pssm-ID: 350839 [Multi-domain]  Cd Length: 65  Bit Score: 97.58  E-value: 1.16e-24
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 924601414 178 MPAGHIVSHLERILGEEQITFEPQALRLLARAAQGSMRDALSLTDQAIAYSANEVTESAVSGMLG 242
Cdd:cd18137    1 ISVEDIVGRLAHILEKEGIEIEDEALELIARAAEGSMRDALSLLDQAIAFGGGRVTLDDVREMLG 65
rfc PRK00440
replication factor C small subunit; Reviewed
9-237 2.18e-23

replication factor C small subunit; Reviewed


Pssm-ID: 234763 [Multi-domain]  Cd Length: 319  Bit Score: 101.87  E-value: 2.18e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414   9 KWRPKDFASLVGQEHVVRALTHALDGGRLHHaYLFTGTRGVGKTTlsrifakalncetgvtsqpCGVCRAcREIdegrFV 88
Cdd:PRK00440  10 KYRPRTLDEIVGQEEIVERLKSYVKEKNMPH-LLFAGPPGTGKTT-------------------AALALA-REL----YG 64
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414  89 DY-----VEMDAASNRGVD-------EMAALleravyAPV-DARFKVYMIDEVHMLTNHAFNAMLKTLEEPPPHVKFILA 155
Cdd:PRK00440  65 EDwrenfLELNASDERGIDvirnkikEFART------APVgGAPFKIIFLDEADNLTSDAQQALRRTMEMYSQNTRFILS 138
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414 156 TTDPQKIPVTVLSRCLQFNLKQMPAGHIVSHLERILGEEQITFEPQALRLLARAAQGSMRDALSLTdQAIAYSANEVTES 235
Cdd:PRK00440 139 CNYSSKIIDPIQSRCAVFRFSPLKKEAVAERLRYIAENEGIEITDDALEAIYYVSEGDMRKAINAL-QAAAATGKEVTEE 217

                 ..
gi 924601414 236 AV 237
Cdd:PRK00440 218 AV 219
PRK06871 PRK06871
DNA polymerase III subunit delta'; Validated
22-175 3.41e-22

DNA polymerase III subunit delta'; Validated


Pssm-ID: 180738 [Multi-domain]  Cd Length: 325  Bit Score: 98.27  E-value: 3.41e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414  22 EHVVRALTHALDGGRLHHAYLFTGTRGVGKTTLSRIFAKALNCETGVTSQPCGVCRACREIDEGRFVDYVEMDAASNR-- 99
Cdd:PRK06871   8 QPTYQQITQAFQQGLGHHALLFKADSGLGTEQLIRALAQWLMCQTPQGDQPCGQCHSCHLFQAGNHPDFHILEPIDNKdi 87
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 924601414 100 GVDEMAALLERAVYAPVDARFKVYMIDEVHMLTNHAFNAMLKTLEEPPPHVKFILATTDPQKIPVTVLSRCLQFNL 175
Cdd:PRK06871  88 GVDQVREINEKVSQHAQQGGNKVVYIQGAERLTEAAANALLKTLEEPRPNTYFLLQADLSAALLPTIYSRCQTWLI 163
PRK08699 PRK08699
DNA polymerase III subunit delta'; Validated
36-175 3.33e-20

DNA polymerase III subunit delta'; Validated


Pssm-ID: 181538 [Multi-domain]  Cd Length: 325  Bit Score: 92.63  E-value: 3.33e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414  36 RLHHAYLFTGTRGVGKTTLSRIFAKALNCETGVTS-QPCGVCRACREIDEGRFVDYVEMDAASNR----------GVDEM 104
Cdd:PRK08699  19 RRPNAWLFAGKKGIGKTAFARFAAQALLCETPAPGhKPCGECMSCHLFGQGSHPDFYEITPLSDEpengrkllqiKIDAV 98
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 924601414 105 AALLERAVYAPVDARFKVYMIDEVHMLTNHAFNAMLKTLEEPPPHVKFILATTDPQKIPVTVLSRCLQFNL 175
Cdd:PRK08699  99 REIIDNVYLTSVRGGLRVILIHPAESMNLQAANSLLKVLEEPPPQVVFLLVSHAADKVLPTIKSRCRKMVL 169
PRK07993 PRK07993
DNA polymerase III subunit delta'; Validated
9-306 8.15e-20

DNA polymerase III subunit delta'; Validated


Pssm-ID: 181190 [Multi-domain]  Cd Length: 334  Bit Score: 91.67  E-value: 8.15e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414   9 KWRP---KDFASLVGQEHvvralthaldGGRLHHAYLFTGTRGVGKTTLSRIFAKALNCETGVTSQPCGVCRACREIDEG 85
Cdd:PRK07993   2 KWYPwlrPDYEQLVGSYQ----------AGRGHHALLIQALPGMGDDALIYALSRWLMCQQPQGHKSCGHCRGCQLMQAG 71
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414  86 RFVDYVEMD---AASNRGVDEMAALLERaVYApvDARF---KVYMIDEVHMLTNHAFNAMLKTLEEPPPHVKFILATTDP 159
Cdd:PRK07993  72 THPDYYTLTpekGKSSLGVDAVREVTEK-LYE--HARLggaKVVWLPDAALLTDAAANALLKTLEEPPENTWFFLACREP 148
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414 160 QKIPVTVLSRCLQFNLKQMPAGHIVSHLERilgeeQITFEPQALRLLARAAQGSMRDALSLTdQAIAYSANEVTESAVSg 239
Cdd:PRK07993 149 ARLLATLRSRCRLHYLAPPPEQYALTWLSR-----EVTMSQDALLAALRLSAGAPGAALALL-QPERWQQREALCQALA- 221
                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 924601414 240 mlGALDQTYMVRLLDALAAANGPEIL-----AIADEMSLRSLSFSTALQDLASLLHRIAwAQFAPG---SVLDEW 306
Cdd:PRK07993 222 --YALPSGDWLSLLPALNHEQAPARLhwlatLLMDALKRQHGAAYVTNQDQPPLVAQLA-NHLSPArlqAILGDV 293
PRK05707 PRK05707
DNA polymerase III subunit delta'; Validated
32-293 1.16e-19

DNA polymerase III subunit delta'; Validated


Pssm-ID: 180215 [Multi-domain]  Cd Length: 328  Bit Score: 90.92  E-value: 1.16e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414  32 LDGGRLHHAYLFTGTRGVGKTTLSRIFAKALNCETGVTSQPCGVCRACREIDEGRFVDYVEM---DAASNRGVDEMAALL 108
Cdd:PRK05707  16 AGRGRHPHAYLLHGPAGIGKRALAERLAAALLCEAPQGGGACGSCKGCQLLRAGSHPDNFVLepeEADKTIKVDQVRELV 95
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414 109 ERAVYAPVDARFKVYMIDEVHMLTNHAFNAMLKTLEEPPPHVKFILATTDPQKIPVTVLSRCLQFNLKQMPAGHIVSHLE 188
Cdd:PRK05707  96 SFVVQTAQLGGRKVVLIEPAEAMNRNAANALLKSLEEPSGDTVLLLISHQPSRLLPTIKSRCQQQACPLPSNEESLQWLQ 175
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414 189 RILGEEQitfEPQALRLLaRAAQGSMRDALSLTDQAIAYSANEVTESAVSGMLGALDQTYMVRlldALAAANGPEILAIA 268
Cdd:PRK05707 176 QALPESD---ERERIELL-TLAGGSPLRALQLHEQGVREQRARVLDGVKKLLKQQQSASQLAE---SWLKVPLLLLFDWF 248
                        250       260       270
                 ....*....|....*....|....*....|..
gi 924601414 269 DEMSLRSLSF-------STALQDLASLLHRIA 293
Cdd:PRK05707 249 CDWAHDILRYqltqdeeGLGLADMRKVLQYLA 280
DNA_pol3_gamma3 pfam12169
DNA polymerase III subunits gamma and tau domain III; This domain family is found in bacteria, ...
232-357 1.37e-19

DNA polymerase III subunits gamma and tau domain III; This domain family is found in bacteria, and is approximately 110 amino acids in length. The family is found in association with pfam00004. Domains I-III are shared between the tau and the gamma subunits, while most of the DnaB-binding Domain IV and all of the alpha-interacting Domain V are unique to tau.


Pssm-ID: 432379 [Multi-domain]  Cd Length: 143  Bit Score: 85.78  E-value: 1.37e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414  232 VTESAVSGMLGALDQTYMVRLLDALAAANGPEILAIADEMSLRSLSFSTALQDLASLLHRIAWAQFAPGSVLDEW---PE 308
Cdd:pfam12169   1 VTAAQVRDMLGLADRGRVLDLLEALLEGDAAAALAELRDQYDAGADPVVVLRDLLELIHNLTRLKVAPDAADDLLlpeEE 80
                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*....
gi 924601414  309 AADLRRFAETLSPEQVQLFYQIATVGRAELGLAPDEYAGFTMTLLRMLA 357
Cdd:pfam12169  81 RARLAELAEKLSPEVLHRLWQMLLKGIEEVPNAPDPRQAAEMVLLRLAY 129
PRK07399 PRK07399
DNA polymerase III subunit delta'; Validated
14-213 1.08e-18

DNA polymerase III subunit delta'; Validated


Pssm-ID: 236011 [Multi-domain]  Cd Length: 314  Bit Score: 87.65  E-value: 1.08e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414  14 DFASLVGQEHVVRALTHALDGGRLHHAYLFTGTRGVGKTTLSRIFAKALncetgVTSQPCGVCRACReIDEGRFVD---- 89
Cdd:PRK07399   2 LFANLIGQPLAIELLTAAIKQNRIAPAYLFAGPEGVGRKLAALCFIEGL-----LSQGSPSKNIRRR-LEEGNHPDllwv 75
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414  90 ---YVEMDAASNRGVDEMAALLERAVYA----------------PVDARFKVYMIDEVHMLTNHAFNAMLKTLEEPPPHV 150
Cdd:PRK07399  76 eptYQHQGKLITASEAEEAGLKRKAPPQirleqireikrflsrpPLEAPRKVVVIEDAETMNEAAANALLKTLEEPGNGT 155
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 924601414 151 kFILATTDPQKIPVTVLSRCLQFNLKQMPAGHIVSHLERILGEEQITFEPQAlrLLArAAQGS 213
Cdd:PRK07399 156 -LILIAPSPESLLPTIVSRCQIIPFYRLSDEQLEQVLKRLGDEEILNINFPE--LLA-LAQGS 214
PRK13342 PRK13342
recombination factor protein RarA; Reviewed
6-237 1.48e-18

recombination factor protein RarA; Reviewed


Pssm-ID: 237355 [Multi-domain]  Cd Length: 413  Bit Score: 88.99  E-value: 1.48e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414   6 LARKWRPKDFASLVGQEHVV---RALTHALDGGRLHHAyLFTGTRGVGKTTLSRIFAKALNCEtgvtsqpcgvcracrei 82
Cdd:PRK13342   2 LAERMRPKTLDEVVGQEHLLgpgKPLRRMIEAGRLSSM-ILWGPPGTGKTTLARIIAGATDAP----------------- 63
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414  83 degrfvdYVEMDAASNrGVDEMAALLERAVYAPVDARFKVYMIDEVhmltnHAFN-----AMLKTLEEppPHVKFILATT 157
Cdd:PRK13342  64 -------FEALSAVTS-GVKDLREVIEEARQRRSAGRRTILFIDEI-----HRFNkaqqdALLPHVED--GTITLIGATT 128
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414 158 DPQKIPVT--VLSRCLQFNLKQMPAGHIVSHLERILGEEQ---ITFEPQALRLLARAAQGSMRDALSLTDQAiAYSANEV 232
Cdd:PRK13342 129 ENPSFEVNpaLLSRAQVFELKPLSEEDIEQLLKRALEDKErglVELDDEALDALARLANGDARRALNLLELA-ALGVDSI 207

                 ....*
gi 924601414 233 TESAV 237
Cdd:PRK13342 208 TLELL 212
PRK14969 PRK14969
DNA polymerase III subunits gamma and tau; Provisional
611-780 4.93e-18

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237873 [Multi-domain]  Cd Length: 527  Bit Score: 88.27  E-value: 4.93e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414 611 GSDDSFVPVFDSGPDDVRVTPKPAETRPAAPIDTRPLPPAialdpiGFDGEWPALAARLPLKGVAYQLAFNSELTAVDAS 690
Cdd:PRK14969 361 SEQDSGAGRAPGAVPGVNRTRAVPTAAPAAPAAATPSDRQ------SFNGNWRALVDQLKLSGLARELAQNCELKSFSED 434
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414 691 TLKLSVP-------VPQYADaaqvtKLKAALADALGKPVEVSVEVG-PARRTAAALDAAARAARQREAEQEIHGDPFVQQ 762
Cdd:PRK14969 435 RIELRVPeahkhllDKPYQD-----KLQAALEQHFGRPVQLIFSLGgVSGNTPAELVSREKAERQSQAESAIESDGFVQE 509
                        170
                 ....*....|....*...
gi 924601414 763 LVRDFGARIVEGSVRPLA 780
Cdd:PRK14969 510 LIEDFDATLIPSSIKPIQ 527
PRK07471 PRK07471
DNA polymerase III subunit delta'; Validated
11-317 1.83e-17

DNA polymerase III subunit delta'; Validated


Pssm-ID: 236022 [Multi-domain]  Cd Length: 365  Bit Score: 85.08  E-value: 1.83e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414  11 RPKDFASLVGQEHVVRALTHALDGGRLHHAYLFTGTRGVGKTTLSRIFAKALNCETGVTSQPCG-------------VCR 77
Cdd:PRK07471  14 HPRETTALFGHAAAEAALLDAYRSGRLHHAWLIGGPQGIGKATLAYRMARFLLATPPPGGDGAVppptslaidpdhpVAR 93
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414  78 ACREIDEGRFvdyvemdAASNRGVDEMAALLeRAVYAPVDAR--------------FKVYMIDEVHMLTNHAFNAMLKTL 143
Cdd:PRK07471  94 RIAAGAHGGL-------LTLERSWNEKGKRL-RTVITVDEVRelisffgltaaeggWRVVIVDTADEMNANAANALLKVL 165
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414 144 EEPPPHVKFILATTDPQKIPVTVLSRCLQFNLKQMPAGHIVSHLERILGEEqitfEPQALRLLARAAQGSMRDALSLTDQ 223
Cdd:PRK07471 166 EEPPARSLFLLVSHAPARLLPTIRSRCRKLRLRPLAPEDVIDALAAAGPDL----PDDPRAALAALAEGSVGRALRLAGG 241
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414 224 aiaysanevtesavsgmlGALD-QTYMVRLLDALAAANGPEILAIADEMSLR----SLSFSTALQD--LASLLHRIAWAQ 296
Cdd:PRK07471 242 ------------------DGLAlYRRLTALLDTLPRLDRRALHALADAAAGRdraaRFALFLDLLDrwLARLARAGARGA 303
                        330       340
                 ....*....|....*....|....*..
gi 924601414 297 FAPGSVLDEWP------EAADLRRFAE 317
Cdd:PRK07471 304 PPPEAVPGEAAllarlaPDARLRRWAE 330
PRK09112 PRK09112
DNA polymerase III subunit delta'; Validated
18-221 2.34e-17

DNA polymerase III subunit delta'; Validated


Pssm-ID: 169667 [Multi-domain]  Cd Length: 351  Bit Score: 84.32  E-value: 2.34e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414  18 LVGQEHVVRALTHALDGGRLHHAYLFTGTRGVGKTTLSRIFAKALNCETGVTSQPCGVCR------ACREIDEG------ 85
Cdd:PRK09112  25 LFGHEEAEAFLAQAYREGKLHHALLFEGPEGIGKATLAFHLANHILSHPDPAEAPETLADpdpaspVWRQIAQGahpnll 104
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414  86 ---RFVDYVEMDAASNRGVDEmaalLERAVY----APVDARFKVYMIDEVHMLTNHAFNAMLKTLEEPPPHVKFILATTD 158
Cdd:PRK09112 105 hitRPFDEKTGKFKTAITVDE----IRRVGHflsqTSGDGNWRIVIIDPADDMNRNAANAILKTLEEPPARALFILISHS 180
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 924601414 159 PQKIPVTVLSRCLQFNLKQMPAGHIVSHLERiLGEEQITFEPQALRLLARaAQGSMRDALSLT 221
Cdd:PRK09112 181 SGRLLPTIRSRCQPISLKPLDDDELKKALSH-LGSSQGSDGEITEALLQR-SKGSVRKALLLL 241
PRK06964 PRK06964
DNA polymerase III subunit delta'; Validated
36-180 9.29e-16

DNA polymerase III subunit delta'; Validated


Pssm-ID: 235898 [Multi-domain]  Cd Length: 342  Bit Score: 79.42  E-value: 9.29e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414  36 RLHHAYLFTGTRGVGKTTLSRIFAKALNCETGVTS-QPCGVCRACREIDEGRFVDYV-----EMDAASNRGVDEMAALLE 109
Cdd:PRK06964  19 RLPHALLLHGQAGIGKLDFAQHLAQGLLCETPQPDgEPCGTCAACNWFAQGNHPDYRivrpeALAAEAPGAADEAKEADA 98
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414 110 RAVYAPVDARFKVYMIDEVHMLTN------------------------HAFNAMLKTLEEPPPHVKFILATTDPQKIPVT 165
Cdd:PRK06964  99 DEGGKKTKAPSKEIKIEQVRALLDfcgvgthrggarvvvlypaealnvAAANALLKTLEEPPPGTVFLLVSARIDRLLPT 178
                        170
                 ....*....|....*
gi 924601414 166 VLSRCLQFNLkQMPA 180
Cdd:PRK06964 179 ILSRCRQFPM-TVPA 192
PRK07276 PRK07276
DNA polymerase III subunit delta'; Validated
21-224 1.61e-15

DNA polymerase III subunit delta'; Validated


Pssm-ID: 180916 [Multi-domain]  Cd Length: 290  Bit Score: 77.75  E-value: 1.61e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414  21 QEHVVRALTHALDGGRLHHAYLFTGtrGVGKTTLSRIFAKALNCETGVTSQPCGVCRACREIDEGRFVDyVEMDAASNR- 99
Cdd:PRK07276   7 QPKVFQRFQTILEQDRLNHAYLFSG--DFASFEMALFLAQSLFCEQKEGVLPCGHCRSCRLIEQGEFSD-VTVIEPQGQv 83
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414 100 ----GVDEMAALLERAVYapvDARFKVYMIDEVH-MLTNHAfNAMLKTLEEPPPHVKFILATTDPQKIPVTVLSRCLQFN 174
Cdd:PRK07276  84 iktdTIRELVKNFSQSGY---EGKQQVFIIKDADkMHVNAA-NSLLKVIEEPQSEIYIFLLTNDENKVLPTIKSRTQIFH 159
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|.
gi 924601414 175 L-KQMPAghivshLERILGEEQItFEPQAlRLLARAAQgSMRDALSLTDQA 224
Cdd:PRK07276 160 FpKNEAY------LIQLLEQKGL-LKTQA-ELLAKLAQ-STSEAEKLAQNK 201
RarA COG2256
Replication-associated recombination protein RarA (DNA-dependent ATPase) [Replication, ...
6-242 8.85e-15

Replication-associated recombination protein RarA (DNA-dependent ATPase) [Replication, recombination and repair];


Pssm-ID: 441857 [Multi-domain]  Cd Length: 439  Bit Score: 77.40  E-value: 8.85e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414   6 LARKWRPKDFASLVGQEHVV---RALTHALDGGRLHHAYLFtGTRGVGKTTLSRIFAKALNCEtgvtsqpcgvcracrei 82
Cdd:COG2256   15 LAERMRPRTLDEVVGQEHLLgpgKPLRRAIEAGRLSSMILW-GPPGTGKTTLARLIANATDAE----------------- 76
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414  83 degrfvdYVEMDAASNrGVDEMAALLERAVYAPVDARFKVYMIDEVhmltnHAFN-----AMLktleeppPHV-----KF 152
Cdd:COG2256   77 -------FVALSAVTS-GVKDIREVIEEARERRAYGRRTILFVDEI-----HRFNkaqqdALL-------PHVedgtiTL 136
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414 153 ILATTD--------PqkipvtVLSRCLQFNLKQMPAGHI-------VSHLERILGEEQITFEPQALRLLARAAQGSMRDA 217
Cdd:COG2256  137 IGATTEnpsfevnsA------LLSRCRVFVLKPLSEEDLeqlleraLADDERGLGGYKLELDDEALEALARLADGDARRA 210
                        250       260
                 ....*....|....*....|....*....
gi 924601414 218 LSLTDQAIAYSAN----EVTESAVSGMLG 242
Cdd:COG2256  211 LNALELAVLSAPPdgviEITLELVEEALQ 239
PRK06090 PRK06090
DNA polymerase III subunit delta'; Validated
31-175 6.36e-14

DNA polymerase III subunit delta'; Validated


Pssm-ID: 180394 [Multi-domain]  Cd Length: 319  Bit Score: 73.68  E-value: 6.36e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414  31 ALDGGRLHHAYLFTGTRGVGKTTLSRIFAKALNCETgVTSQPCGVCRACREIDEGRFVDY-------------VEMDAAS 97
Cdd:PRK06090  18 GLDAGRIPGALLLQSDEGLGVESLVELFSRALLCQN-YQSEACGFCHSCELMQSGNHPDLhvikpekegksitVEQIRQC 96
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 924601414  98 NRGVDEMAALleravyapvdARFKVYMIDEVHMLTNHAFNAMLKTLEEPPPHVKFILATTDPQKIPVTVLSRCLQFNL 175
Cdd:PRK06090  97 NRLAQESSQL----------NGYRLFVIEPADAMNESASNALLKTLEEPAPNCLFLLVTHNQKRLLPTIVSRCQQWVV 164
PRK05917 PRK05917
DNA polymerase III subunit delta'; Validated
115-214 1.65e-13

DNA polymerase III subunit delta'; Validated


Pssm-ID: 102059 [Multi-domain]  Cd Length: 290  Bit Score: 71.75  E-value: 1.65e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414 115 PVDARFKVYMIDEVHMLTNHAFNAMLKTLEEPPPHVKFILATTDPQKIPVTVLSRCLQFnlkqmpaghivshleRILGEE 194
Cdd:PRK05917  91 PYESPYKIYIIHEADRMTLDAISAFLKVLEDPPQHGVIILTSAKPQRLPPTIRSRSLSI---------------HIPMEE 155
                         90       100
                 ....*....|....*....|
gi 924601414 195 QITFEPQALRLLARAAQGSM 214
Cdd:PRK05917 156 KTLVSKEDIAYLIGYAQGKE 175
PRK05564 PRK05564
DNA polymerase III subunit delta'; Validated
14-178 3.90e-13

DNA polymerase III subunit delta'; Validated


Pssm-ID: 180132 [Multi-domain]  Cd Length: 313  Bit Score: 71.22  E-value: 3.90e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414  14 DFASLVGQEHVVRALTHALDGGRLHHAYLFTGTRGVGKTTLSRIFA-KALNcetgvtsqpcgvcracreIDEGR-FVDYV 91
Cdd:PRK05564   2 SFHTIIGHENIKNRIKNSIIKNRFSHAHIIVGEDGIGKSLLAKEIAlKILG------------------KSQQReYVDII 63
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414  92 EMDAASNR--GVDEMAALLERAVYAPVDARFKVYMIDEVHMLTNHAFNAMLKTLEEPPPHVKFILATTDPQKIPVTVLSR 169
Cdd:PRK05564  64 EFKPINKKsiGVDDIRNIIEEVNKKPYEGDKKVIIIYNSEKMTEQAQNAFLKTIEEPPKGVFIILLCENLEQILDTIKSR 143

                 ....*....
gi 924601414 170 CLQFNLKQM 178
Cdd:PRK05564 144 CQIYKLNRL 152
PRK04195 PRK04195
replication factor C large subunit; Provisional
9-265 1.16e-12

replication factor C large subunit; Provisional


Pssm-ID: 235250 [Multi-domain]  Cd Length: 482  Bit Score: 71.11  E-value: 1.16e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414   9 KWRPKDFASLVGQEHVVRALT---HALDGGRLHHAYLFTGTRGVGKTTLsrifAKALncetgvtsqpcgvcraCREIDeg 85
Cdd:PRK04195   7 KYRPKTLSDVVGNEKAKEQLRewiESWLKGKPKKALLLYGPPGVGKTSL----AHAL----------------ANDYG-- 64
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414  86 rfVDYVEMDAASNRGVDEMAALLERA-VYAPV-DARFKVYMIDEVHMLTNHA----FNAMLKTLEEPPPHVkfILATTDP 159
Cdd:PRK04195  65 --WEVIELNASDQRTADVIERVAGEAaTSGSLfGARRKLILLDEVDGIHGNEdrggARAILELIKKAKQPI--ILTANDP 140
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414 160 QKIP-VTVLSRCLQFNLKQMPAGHIVSHLERILGEEQITFEPQALRLLARAAQGSMRDAlsLTD-QAIAYSANEVTESAV 237
Cdd:PRK04195 141 YDPSlRELRNACLMIEFKRLSTRSIVPVLKRICRKEGIECDDEALKEIAERSGGDLRSA--INDlQAIAEGYGKLTLEDV 218
                        250       260
                 ....*....|....*....|....*....
gi 924601414 238 SgMLGALDQTY-MVRLLDALAAANGPEIL 265
Cdd:PRK04195 219 K-TLGRRDREEsIFDALDAVFKARNADQA 246
AAA cd00009
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily ...
19-170 2.38e-12

The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC, RecA-like, VirD4-like, PilT-like, and SF1/2 helicases. Members of the AAA+ ATPases function as molecular chaperons, ATPase subunits of proteases, helicases, or nucleic-acid stimulated ATPases. The AAA+ proteins contain several distinct features in addition to the conserved alpha-beta-alpha core domain structure and the Walker A and B motifs of the P-loop NTPases.


Pssm-ID: 99707 [Multi-domain]  Cd Length: 151  Bit Score: 65.25  E-value: 2.38e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414  19 VGQEHVVRALTHALDGGRLHHaYLFTGTRGVGKTTLSRIFAKALNcETGVTsqpcgVCracrEIDEGRFvdYVEMDAASN 98
Cdd:cd00009    1 VGQEEAIEALREALELPPPKN-LLLYGPPGTGKTTLARAIANELF-RPGAP-----FL----YLNASDL--LEGLVVAEL 67
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414  99 RGVDEMAALLERAVYAPVDarfkVYMIDEVHMLTNHAFNAMLKTLEE------PPPHVKFILATTDP--QKIPVTVLSRC 170
Cdd:cd00009   68 FGHFLVRLLFELAEKAKPG----VLFIDEIDSLSRGAQNALLRVLETlndlriDRENVRVIGATNRPllGDLDRALYDRL 143
PLN03025 PLN03025
replication factor C subunit; Provisional
9-218 4.84e-11

replication factor C subunit; Provisional


Pssm-ID: 178596 [Multi-domain]  Cd Length: 319  Bit Score: 64.75  E-value: 4.84e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414   9 KWRPKDFASLVGQEHVVRALTHALDGGRLHHaYLFTGTRGVGKTTlsRIFAKAlncetgvtsqpcgvcracREIDEGRFV 88
Cdd:PLN03025   6 KYRPTKLDDIVGNEDAVSRLQVIARDGNMPN-LILSGPPGTGKTT--SILALA------------------HELLGPNYK 64
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414  89 DYV-EMDAASNRGVD------EMAAllERAVYAPVdARFKVYMIDEVHMLTNHAFNAMLKTLEEPPPHVKFILATTDPQK 161
Cdd:PLN03025  65 EAVlELNASDDRGIDvvrnkiKMFA--QKKVTLPP-GRHKIVILDEADSMTSGAQQALRRTMEIYSNTTRFALACNTSSK 141
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 924601414 162 IPVTVLSRCLQFNLKQMPAGHIVSHLERILGEEQITFEPQALRLLARAAQGSMRDAL 218
Cdd:PLN03025 142 IIEPIQSRCAIVRFSRLSDQEILGRLMKVVEAEKVPYVPEGLEAIIFTADGDMRQAL 198
PRK08769 PRK08769
DNA polymerase III subunit delta'; Validated
31-180 4.79e-10

DNA polymerase III subunit delta'; Validated


Pssm-ID: 181551 [Multi-domain]  Cd Length: 319  Bit Score: 61.90  E-value: 4.79e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414  31 ALDGGRLHHAYLFTGTRGVGKTTLSRIFAKALnceTGVTSQPCGVCRACREIDEGRFVDYVEMDAASNRGVDEMAA---- 106
Cdd:PRK08769  19 ALDAGRLGHGLLICGPEGLGKRAVALALAEHV---LASGPDPAAAQRTRQLIAAGTHPDLQLVSFIPNRTGDKLRTeivi 95
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 924601414 107 -----LLERAVYAPVDARFKVYMIDEVHMLTNHAFNAMLKTLEEPPPHVKFILATTDPQKIPVTVLSRCLQFNLKQMPA 180
Cdd:PRK08769  96 eqvreISQKLALTPQYGIAQVVIVDPADAINRAACNALLKTLEEPSPGRYLWLISAQPARLPATIRSRCQRLEFKLPPA 174
PRK04132 PRK04132
replication factor C small subunit; Provisional
89-228 5.16e-10

replication factor C small subunit; Provisional


Pssm-ID: 235223 [Multi-domain]  Cd Length: 846  Bit Score: 63.32  E-value: 5.16e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414  89 DYVEMDAASNRGVDEM-AALLERAVYAPV-DARFKVYMIDEVHMLTNHAFNAMLKTLEEPPPHVKFILATTDPQKIPVTV 166
Cdd:PRK04132 598 NFLELNASDERGINVIrEKVKEFARTKPIgGASFKIIFLDEADALTQDAQQALRRTMEMFSSNVRFILSCNYSSKIIEPI 677
                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 924601414 167 LSRCLQFNLKQMPAGHIVSHLERILGEEQITFEPQALRLLARAAQGSMRDALSLTDQAIAYS 228
Cdd:PRK04132 678 QSRCAIFRFRPLRDEDIAKRLRYIAENEGLELTEEGLQAILYIAEGDMRRAINILQAAAALD 739
44 PHA02544
clamp loader, small subunit; Provisional
9-203 7.10e-10

clamp loader, small subunit; Provisional


Pssm-ID: 222866 [Multi-domain]  Cd Length: 316  Bit Score: 61.16  E-value: 7.10e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414   9 KWRPKDFASLVGQEHVVRALTHALDGGRLHHAYLFTGTRGVGKTTLsrifAKALncetgvtsqpcgvcraCREIDegrfV 88
Cdd:PHA02544  14 KYRPSTIDECILPAADKETFKSIVKKGRIPNMLLHSPSPGTGKTTV----AKAL----------------CNEVG----A 69
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414  89 DYVEMDAASNRgVDEMAALLER-AVYAPVDARFKVYMIDEVHMLTNHAFNAMLKTL-EEPPPHVKFILATTDPQKIPVTV 166
Cdd:PHA02544  70 EVLFVNGSDCR-IDFVRNRLTRfASTVSLTGGGKVIIIDEFDRLGLADAQRHLRSFmEAYSKNCSFIITANNKNGIIEPL 148
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*....
gi 924601414 167 LSRC--LQFN----------LKQMpaghiVSHLERILGEEQITFEPQAL 203
Cdd:PHA02544 149 RSRCrvIDFGvptkeeqiemMKQM-----IVRCKGILEAEGVEVDMKVL 192
PRK07132 PRK07132
DNA polymerase III subunit delta'; Validated
116-187 4.12e-08

DNA polymerase III subunit delta'; Validated


Pssm-ID: 180855 [Multi-domain]  Cd Length: 299  Bit Score: 55.50  E-value: 4.12e-08
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 924601414 116 VDARFKVYMIDEVHMLTNHAFNAMLKTLEEPPPHVKFILATTDPQKIPVTVLSRCLQFNLKQMPAGHIVSHL 187
Cdd:PRK07132  87 VQSQKKILIIKNIEKTSNSLLNALLKTIEEPPKDTYFLLTTKNINKVLPTIVSRCQVFNVKEPDQQKILAKL 158
PRK13341 PRK13341
AAA family ATPase;
6-220 5.32e-08

AAA family ATPase;


Pssm-ID: 237354 [Multi-domain]  Cd Length: 725  Bit Score: 56.60  E-value: 5.32e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414   6 LARKWRPKDFASLVGQEHVV---RALTHALDGGRLHHAyLFTGTRGVGKTTLSRIFAKALNCEtgvtsqpcgvcracrei 82
Cdd:PRK13341  18 LADRLRPRTLEEFVGQDHILgegRLLRRAIKADRVGSL-ILYGPPGVGKTTLARIIANHTRAH----------------- 79
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414  83 degrfvdYVEMDAASNrGVDEMAALLERAvyapvDARFKVY------MIDEVHMLTNHAFNAMLktleeppPHVK----- 151
Cdd:PRK13341  80 -------FSSLNAVLA-GVKDLRAEVDRA-----KERLERHgkrtilFIDEVHRFNKAQQDALL-------PWVEngtit 139
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 924601414 152 FILATTDPQKIPV--TVLSRCLQFNLKQMPAGHIVSHLERIL-------GEEQITFEPQALRLLARAAQGsmrDALSL 220
Cdd:PRK13341 140 LIGATTENPYFEVnkALVSRSRLFRLKSLSDEDLHQLLKRALqdkergyGDRKVDLEPEAEKHLVDVANG---DARSL 214
AAA pfam00004
ATPase family associated with various cellular activities (AAA); AAA family proteins often ...
41-170 1.20e-07

ATPase family associated with various cellular activities (AAA); AAA family proteins often perform chaperone-like functions that assist in the assembly, operation, or disassembly of protein complexes.


Pssm-ID: 459627 [Multi-domain]  Cd Length: 130  Bit Score: 51.05  E-value: 1.20e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414   41 YLFTGTRGVGKTTLSRIFAKALNcetgvtsqpcgvcracreidegrfVDYVEMDAAS--NRGVDEMAALLERAVYAPVDA 118
Cdd:pfam00004   1 LLLYGPPGTGKTTLAKAVAKELG------------------------APFIEISGSElvSKYVGESEKRLRELFEAAKKL 56
                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 924601414  119 RFKVYMIDEVHMLTNH-----------AFNAMLKTLEEP---PPHVKFILATTDPQKIPVTVLSRC 170
Cdd:pfam00004  57 APCVIFIDEIDALAGSrgsggdsesrrVVNQLLTELDGFtssNSKVIVIAATNRPDKLDPALLGRF 122
PRK05818 PRK05818
DNA polymerase III subunit delta'; Validated
58-173 2.35e-07

DNA polymerase III subunit delta'; Validated


Pssm-ID: 235618 [Multi-domain]  Cd Length: 261  Bit Score: 52.91  E-value: 2.35e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414  58 FAKALNCETgvTSQPCGVCRACREIDEGRFVD-YVEMDAASNRGVDEMAALLERAVYAPVDAR-FKVYMIDEVHMLTNHA 135
Cdd:PRK05818  27 YLTSIVCTK--ANGFCKTCESCLKILNGKYNDfYLIFDQKNPIKKEDALSIINKLNRPSVESNgKKIYIIYGIEKLNKQS 104
                         90       100       110
                 ....*....|....*....|....*....|....*...
gi 924601414 136 FNAMLKTLEEPPPHVKFILATTDPQKIPVTVLSRCLQF 173
Cdd:PRK05818 105 ANSLLKLIEEPPKNTYGIFTTRNENNILNTILSRCVQY 142
AAA smart00382
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ...
38-162 2.61e-07

ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.


Pssm-ID: 214640 [Multi-domain]  Cd Length: 148  Bit Score: 50.83  E-value: 2.61e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414    38 HHAYLFTGTRGVGKTTLSRIFAKALNCETGvtsqpcGVCRAC-----REIDEGRFVDYVEMDAASNRGVDEMAALLERAV 112
Cdd:smart00382   2 GEVILIVGPPGSGKTTLARALARELGPPGG------GVIYIDgedilEEVLDQLLLIIVGGKKASGSGELRLRLALALAR 75
                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 924601414   113 YAPVDarfkVYMIDEVHMLTNHAFNAML--------KTLEEPPPHVKFILATTDPQKI 162
Cdd:smart00382  76 KLKPD----VLILDEITSLLDAEQEALLllleelrlLLLLKSEKNLTVILTTNDEKDL 129
DNA_pol3_tau_5 pfam12170
DNA polymerase III tau subunit V interacting with alpha; This domain family is found in ...
661-776 5.85e-07

DNA polymerase III tau subunit V interacting with alpha; This domain family is found in bacteria, and is approximately 140 amino acids in length. The family is found in association with pfam00004. Domains I-III are shared between the tau and the gamma subunits, while most of the DnaB-binding Domain IV and all of the alpha-interacting Domain V are unique to tau. The extreme C-terminal region of this domain 5 is the part which interacts with the alpha subunit of the DNA polymerase III holoenzyme.


Pssm-ID: 432380 [Multi-domain]  Cd Length: 142  Bit Score: 49.56  E-value: 5.85e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414  661 EWPALAARLPLKGVAYQLAFNSELTAVDASTLKLSVPVPQ---YADAAQvTKLKAALADALGKPVEVSVEVG--PARRTA 735
Cdd:pfam12170  23 PWAALIERLGLPKLVQQLALNSVLEQQQDDQILLHLRSSQrhlNSDSAQ-KALAEALSELLGKPVELTITEGddPEQKTP 101
                          90       100       110       120
                  ....*....|....*....|....*....|....*....|.
gi 924601414  736 AALDAAARAARQREAEQEIHGDPFVQQLVRDFGARIVEGSV 776
Cdd:pfam12170 102 LEWRQAIYEEKLEQARQSLQADPNVQLLQQRFDAELDEDSI 142
HLD_clamp cd18133
helical lid domain of clamp loader-like AAA+ proteins; Clamp loader complexes are multisubunit ...
179-241 1.29e-06

helical lid domain of clamp loader-like AAA+ proteins; Clamp loader complexes are multisubunit complexes that play an important role in DNA replication. They open sliding clamps for assembly and close them around DNA, specifically targeting them to sites where DNA synthesis is initiated and orienting them correctly for replication. The subunits belong to the clamp loader clade of AAA+ superfamily.


Pssm-ID: 350838 [Multi-domain]  Cd Length: 65  Bit Score: 46.31  E-value: 1.29e-06
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 924601414 179 PAGHIVSHLERILGEEQITFEPQALRLLARAAQGSMRDALSLTDQAIA-YSANEVTESAVSGML 241
Cdd:cd18133    2 DQEQLKRRLAAIAEQEKLKLDDAALQALAYISEGDLRKALNALQRAAAlGDDGKISLDRVYQAV 65
HLD_clamp_RFC cd18140
helical lid domain of replication factor C subunit; Replication factor C (RFC) is five-protein ...
179-238 2.20e-05

helical lid domain of replication factor C subunit; Replication factor C (RFC) is five-protein clamp loader complex that forms a stable ATP-dependent complex with the sliding clamp, PCNA, which binds specifically to primed DNA. RFC subunits belong to the clamp loader clade of the AAA+ superfamily.


Pssm-ID: 350842 [Multi-domain]  Cd Length: 63  Bit Score: 42.90  E-value: 2.20e-05
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 924601414 179 PAGHIVSHLERILGEEQITFEPQALRLLARAAQGSMRDAL-SLtdQAIAYSANEVTESAVS 238
Cdd:cd18140    2 SKEQIVKRLREICKKEGVKIDEEALEAIAEKSEGDMRKAInDL--QAAAAGGGVITEEDVY 60
PRK08485 PRK08485
DNA polymerase III subunit delta'; Validated
135-177 3.68e-05

DNA polymerase III subunit delta'; Validated


Pssm-ID: 236274 [Multi-domain]  Cd Length: 206  Bit Score: 45.41  E-value: 3.68e-05
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|...
gi 924601414 135 AFNAMLKTLEEPPPHVKFILATTDPQKIPVTVLSRCLQFNLKQ 177
Cdd:PRK08485  70 AQNALLKILEEPPKNICFIIVAKSKNLLLPTIRSRLIIEKRKQ 112
RuvB_N pfam05496
Holliday junction DNA helicase RuvB P-loop domain; The RuvB protein makes up part of the ...
11-72 5.76e-05

Holliday junction DNA helicase RuvB P-loop domain; The RuvB protein makes up part of the RuvABC revolvasome which catalyzes the resolution of Holliday junctions that arise during genetic recombination and DNA repair. Branch migration is catalyzed by the RuvB protein that is targeted to the Holliday junction by the structure specific RuvA protein. This family contains the N-terminal region of the protein.


Pssm-ID: 398900 [Multi-domain]  Cd Length: 159  Bit Score: 44.03  E-value: 5.76e-05
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 924601414   11 RPKDFASLVGQEHVVRALTHALDGGR-----LHHAyLFTGTRGVGKTTLSRIFAKALNCETGVTSQP 72
Cdd:pfam05496   2 RPRTLDEYIGQEKVKENLKIFIEAAKqrgeaLDHV-LLYGPPGLGKTTLANIIANEMGVNIRITSGP 67
RuvB COG2255
Holliday junction resolvasome RuvABC, ATP-dependent DNA helicase subunit RuvB [Replication, ...
11-72 1.90e-04

Holliday junction resolvasome RuvABC, ATP-dependent DNA helicase subunit RuvB [Replication, recombination and repair];


Pssm-ID: 441856 [Multi-domain]  Cd Length: 337  Bit Score: 44.30  E-value: 1.90e-04
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 924601414  11 RPKDFASLVGQEHVVRALTHALDGGR-----LHHAyLFTGTRGVGKTTLSRIFAKALNCETGVTSQP 72
Cdd:COG2255   23 RPKRLDEYIGQEKVKENLKIFIEAAKkrgeaLDHV-LLYGPPGLGKTTLAHIIANEMGVNIRITSGP 88
PRK04132 PRK04132
replication factor C small subunit; Provisional
9-51 2.76e-04

replication factor C small subunit; Provisional


Pssm-ID: 235223 [Multi-domain]  Cd Length: 846  Bit Score: 44.44  E-value: 2.76e-04
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|...
gi 924601414   9 KWRPKDFASLVGQEHVVRALTHALDGGRLHHaYLFTGTRGVGK 51
Cdd:PRK04132  12 KYRPQRLDDIVGQEHIVKRLKHYVKTGSMPH-LLFAGPPGVGK 53
ruvB PRK00080
Holliday junction branch migration DNA helicase RuvB;
11-72 3.67e-04

Holliday junction branch migration DNA helicase RuvB;


Pssm-ID: 234619 [Multi-domain]  Cd Length: 328  Bit Score: 43.58  E-value: 3.67e-04
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 924601414  11 RPKDFASLVGQEHVVRALTHALDGGR-----LHHAyLFTGTRGVGKTTLSRIFAKALNCETGVTSQP 72
Cdd:PRK00080  20 RPKSLDEFIGQEKVKENLKIFIEAAKkrgeaLDHV-LLYGPPGLGKTTLANIIANEMGVNIRITSGP 85
PRK06581 PRK06581
DNA polymerase III subunit delta'; Validated
92-188 1.12e-03

DNA polymerase III subunit delta'; Validated


Pssm-ID: 235833 [Multi-domain]  Cd Length: 263  Bit Score: 41.75  E-value: 1.12e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414  92 EMDAASNR---GVDEMAALLERAVYAPVDARFKVYMIDEVHMLTNHAFNAMLKTLEEPPPHVKFILATTDPQKIPVTVLS 168
Cdd:PRK06581  59 ETSATSNAkniSIEQIRKLQDFLSKTSAISGYKVAIIYSAELMNLNAANSCLKILEDAPKNSYIFLITSRAASIISTIRS 138
                         90       100
                 ....*....|....*....|
gi 924601414 169 RCLQFNLKQmPAGHIVSHLE 188
Cdd:PRK06581 139 RCFKINVRS-SILHAYNELY 157
AAA_16 pfam13191
AAA ATPase domain; This family of domains contain a P-loop motif that is characteriztic of the ...
18-63 3.05e-03

AAA ATPase domain; This family of domains contain a P-loop motif that is characteriztic of the AAA superfamily.


Pssm-ID: 433025 [Multi-domain]  Cd Length: 167  Bit Score: 39.41  E-value: 3.05e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*...
gi 924601414   18 LVGQEHVVRALTHALDGGRLH--HAYLFTGTRGVGKTTLSRIFAKALN 63
Cdd:pfam13191   2 LVGREEELEQLLDALDRVRSGrpPSVLLTGEAGTGKTTLLRELLRALE 49
AAA_14 pfam13173
AAA domain; This family of domains contain a P-loop motif that is characteriztic of the AAA ...
38-155 3.16e-03

AAA domain; This family of domains contain a P-loop motif that is characteriztic of the AAA superfamily.


Pssm-ID: 463799 [Multi-domain]  Cd Length: 128  Bit Score: 38.34  E-value: 3.16e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414   38 HHAYLFTGTRGVGKTTLSRIFAKALncetgvtsqpcgvcracreIDEGRFVdYVEMDAASNRGVDEmaALLERAVYAPVD 117
Cdd:pfam13173   2 RKILVITGPRQVGKTTLLLQLIKEL-------------------LPPENIL-YINLDDPRLLKLAD--FELLELFLELLY 59
                          90       100       110
                  ....*....|....*....|....*....|....*...
gi 924601414  118 ARFKVYMIDEVHMLTNhAFNAmLKTLEEPPPHVKFILA 155
Cdd:pfam13173  60 PGKTYLFLDEIQRVPD-WELA-LKRLYDDGPNGRVILT 95
SpoVK COG0464
AAA+-type ATPase, SpoVK/Ycf46/Vps4 family [Cell wall/membrane/envelope biogenesis, Cell cycle ...
6-169 3.80e-03

AAA+-type ATPase, SpoVK/Ycf46/Vps4 family [Cell wall/membrane/envelope biogenesis, Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];


Pssm-ID: 440232 [Multi-domain]  Cd Length: 397  Bit Score: 40.28  E-value: 3.80e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414   6 LARKWRPKDFASLVGQEHVVRALTHA----LDGGRLHHAY--------LFTGTRGVGKTTLSRIFAKALNcetgvtsqpc 73
Cdd:COG0464  147 ELLELREAILDDLGGLEEVKEELRELvalpLKRPELREEYglppprglLLYGPPGTGKTLLARALAGELG---------- 216
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924601414  74 gvcRACREIDEGRFVD-YVEmDAASNrgvdeMAALLERA-VYAPVdarfkVYMIDEVHML-----------TNHAFNAML 140
Cdd:COG0464  217 ---LPLIEVDLSDLVSkYVG-ETEKN-----LREVFDKArGLAPC-----VLFIDEADALagkrgevgdgvGRRVVNTLL 282
                        170       180
                 ....*....|....*....|....*....
gi 924601414 141 KTLEEPPPHVKFILATTDPQKIPVTVLSR 169
Cdd:COG0464  283 TEMEELRSDVVVIAATNRPDLLDPALLRR 311
Mg_chelatase pfam01078
Magnesium chelatase, subunit ChlI; Magnesium-chelatase is a three-component enzyme that ...
14-56 4.48e-03

Magnesium chelatase, subunit ChlI; Magnesium-chelatase is a three-component enzyme that catalyzes the insertion of Mg2+ into protoporphyrin IX. This is the first unique step in the synthesis of (bacterio)chlorophyll. Due to this, it is thought that Mg-chelatase has an important role in channelling inter- mediates into the (bacterio)chlorophyll branch in response to conditions suitable for photosynthetic growth. ChlI and BchD have molecular weight between 38-42 kDa.


Pssm-ID: 426032 [Multi-domain]  Cd Length: 207  Bit Score: 39.06  E-value: 4.48e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|...
gi 924601414   14 DFASLVGQEHVVRALTHALDGGrlhHAYLFTGTRGVGKTTLSR 56
Cdd:pfam01078   1 DLADVKGQEQAKRALEIAAAGG---HNLLMIGPPGSGKTMLAK 40
rne PRK10811
ribonuclease E; Reviewed
461-510 4.71e-03

ribonuclease E; Reviewed


Pssm-ID: 236766 [Multi-domain]  Cd Length: 1068  Bit Score: 40.41  E-value: 4.71e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|.
gi 924601414  461 LPQ-PETKAAPAGDMPPPTRKEPEPPAVAAVQRNDEPAPQAEPAPRAASPE 510
Cdd:PRK10811  502 LPKlHEEAMALPSEEEFAERKRPEQPALATFAMPDVPPAPTPAEPAAPVVA 552
TsaE pfam02367
Threonylcarbamoyl adenosine biosynthesis protein TsaE; This family of proteins is involved in ...
26-70 4.84e-03

Threonylcarbamoyl adenosine biosynthesis protein TsaE; This family of proteins is involved in the synthesis of threonylcarbamoyl adenosine (t(6)A).


Pssm-ID: 460540  Cd Length: 127  Bit Score: 37.80  E-value: 4.84e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*
gi 924601414   26 RALTHALDGGRLhhaYLFTGTRGVGKTTLSRIFAKALNCETGVTS 70
Cdd:pfam02367  12 KRLAALLKPGDV---ILLSGDLGAGKTTFTRGLARGLGVTGPVTS 53
TsaE COG0802
tRNA A37 threonylcarbamoyladenosine biosynthesis protein TsaE [Translation, ribosomal ...
22-70 9.89e-03

tRNA A37 threonylcarbamoyladenosine biosynthesis protein TsaE [Translation, ribosomal structure and biogenesis]; tRNA A37 threonylcarbamoyladenosine biosynthesis protein TsaE is part of the Pathway/BioSystem: tRNA modification


Pssm-ID: 440565  Cd Length: 146  Bit Score: 37.38  E-value: 9.89e-03
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*....
gi 924601414  22 EHVVRALTHALDGGRLhhaYLFTGTRGVGKTTLSRIFAKALNCETGVTS 70
Cdd:COG0802    8 EALGARLAALLKPGDV---ILLEGDLGAGKTTFVRGLARGLGVTGEVTS 53
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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