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topoisomerase IV subunit A [Streptococcus pneumoniae]
Protein Classification
DNA topoisomerase IV subunit A ( domain architecture ID 11490144 )
DNA topoisomerase IV subunit A is a component of the type II topoisomerase required for the decatenation of chromosome segregation
List of domain hits
Name
Accession
Description
Interval
E-value
parC_Gpos
TIGR01061 DNA topoisomerase IV, A subunit, Gram-positive; Operationally, topoisomerase IV is a type II ...
4-743
0e+00
DNA topoisomerase IV, A subunit, Gram-positive; Operationally, topoisomerase IV is a type II topoisomerase required for the decatenation of chromosome segregation. Not every bacterium has both a topo II and a topo IV. The topo IV families of the Gram-positive bacteria and the Gram-negative bacteria appear not to represent a single clade among the type II topoisomerases, and are represented by separate models for this reason. [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 273422 [Multi-domain]
Cd Length: 738
Bit Score: 1247.77
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9230561 4 I Q N MS LE DIM GE R FG R Y S KYIIQDRALPDIRDGLKPVQRRILY S M NK D S NTFDK S Y R KSA KS VG N IMG NF HPHGDSSIYD 83
Cdd:TIGR01061 1 I F N KP LE EVF GE S FG K Y A KYIIQDRALPDIRDGLKPVQRRILY A M FQ D G NTFDK P Y K KSA RT VG E IMG KY HPHGDSSIYD 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9230561 84 AMVRMSQ N WKN REI LVEMHGNNGS M DGD PP AAMRYTEARLS E IA GY LL Q DI E KKTV P F AW NFDD T EKEPTVLPA A FPNLL 163
Cdd:TIGR01061 81 AMVRMSQ D WKN NWT LVEMHGNNGS I DGD NA AAMRYTEARLS L IA SE LL K DI D KKTV S F IP NFDD S EKEPTVLPA L FPNLL 160
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9230561 164 V NG S TGI S AGYAT D IPPHNL A EVIDA AV Y M IDHP TAKI DKLME FLP GPDFPTG A IIQG R D E I K KAYETGKG RVVV R S K T E 243
Cdd:TIGR01061 161 I NG A TGI A AGYAT N IPPHNL N EVIDA LI Y R IDHP NCSV DKLME IVK GPDFPTG G IIQG E D G I S KAYETGKG KFII R A K I E 240
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9230561 244 IE KL K G G KE QIVITEIPYE I NKAN L VKKI DDVRVN NKVAGI A EVRDESDR D G L RI A IELKKDAN T E LV LN Y LFK Y TDLQI 323
Cdd:TIGR01061 241 IE VN K N G LN QIVITEIPYE T NKAN I VKKI EEIIFD NKVAGI E EVRDESDR N G I RI I IELKKDAN A E KI LN F LFK H TDLQI 320
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9230561 324 NYNFNMVAI D N F TP R QVG IVPI L SS YI A H RR EVI LA RS PFDK EKA E KRL R IVEGLI RV ISI L DE V I A LIR A SE N K A D P KE 403
Cdd:TIGR01061 321 NYNFNMVAI A N R TP I QVG LLSY L DA YI K H CH EVI IN RS KYEL EKA S KRL E IVEGLI KA ISI I DE I I K LIR S SE D K S D A KE 400
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9230561 404 NL KVSYD FTE E QAEAIV T L Q LYRLTNTD VVV L Q EE EA EL RE KI AM L AA II GD E RTMYN L M KK E L R E V KK N FA TP R L S SL E 483
Cdd:TIGR01061 401 NL IDNFK FTE N QAEAIV S L R LYRLTNTD IFE L K EE QN EL EK KI IS L EQ II AS E KARNK L L KK Q L E E Y KK Q FA QQ R R S QI E 480
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9230561 484 D TAKA I E I DTAS LI AE ED T YV SV TKAGYIKRTS P RSFA A S TLEEI G KR DDD R L IFVQS A K TT QHL L M FTSLGN V I YR P I H 563
Cdd:TIGR01061 481 D FINQ I K I NESE LI EN ED Y YV LI TKAGYIKRTS N RSFA S S KYTDF G SK DDD I L FAQTI A N TT DQI L I FTSLGN I I NI P V H 560
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9230561 564 E LADIRWKD I GEHLS QT IT n F ET NE A I LY V EVLDQ FD - D ATTYFA A TR LG QI KR V E RK E FTPW R T yr SK SVKYA KLKD DT 642
Cdd:TIGR01061 561 K LADIRWKD L GEHLS NK IT - F DE NE T I VF V GTMNE FD v D QPILVL A SK LG MV KR I E LT E LNIK R N -- SK ATLCI KLKD KD 637
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9230561 643 DQ I V A VAPI K LDDVV LVS QN GYAL R F NIE E V PVVGAKAAGVK A M N LKEDD VLQ SG F I CNTS - S FY LLTQRGS L KR V SI E E 721
Cdd:TIGR01061 638 HL I S A FLQQ K DKLIC LVS DL GYAL V F HTN E I PVVGAKAAGVK G M K LKEDD QVK SG V I FEAN e S LV LLTQRGS V KR L SI S E 717
730 740
....*....|....*....|..
gi 9230561 722 ILA TSRA KR G LQV L r E LK N KPH 743
Cdd:TIGR01061 718 LVV TSRA AT G KKL L - P LK K KPH 738
Name
Accession
Description
Interval
E-value
parC_Gpos
TIGR01061 DNA topoisomerase IV, A subunit, Gram-positive; Operationally, topoisomerase IV is a type II ...
4-743
0e+00
DNA topoisomerase IV, A subunit, Gram-positive; Operationally, topoisomerase IV is a type II topoisomerase required for the decatenation of chromosome segregation. Not every bacterium has both a topo II and a topo IV. The topo IV families of the Gram-positive bacteria and the Gram-negative bacteria appear not to represent a single clade among the type II topoisomerases, and are represented by separate models for this reason. [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 273422 [Multi-domain]
Cd Length: 738
Bit Score: 1247.77
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9230561 4 I Q N MS LE DIM GE R FG R Y S KYIIQDRALPDIRDGLKPVQRRILY S M NK D S NTFDK S Y R KSA KS VG N IMG NF HPHGDSSIYD 83
Cdd:TIGR01061 1 I F N KP LE EVF GE S FG K Y A KYIIQDRALPDIRDGLKPVQRRILY A M FQ D G NTFDK P Y K KSA RT VG E IMG KY HPHGDSSIYD 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9230561 84 AMVRMSQ N WKN REI LVEMHGNNGS M DGD PP AAMRYTEARLS E IA GY LL Q DI E KKTV P F AW NFDD T EKEPTVLPA A FPNLL 163
Cdd:TIGR01061 81 AMVRMSQ D WKN NWT LVEMHGNNGS I DGD NA AAMRYTEARLS L IA SE LL K DI D KKTV S F IP NFDD S EKEPTVLPA L FPNLL 160
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9230561 164 V NG S TGI S AGYAT D IPPHNL A EVIDA AV Y M IDHP TAKI DKLME FLP GPDFPTG A IIQG R D E I K KAYETGKG RVVV R S K T E 243
Cdd:TIGR01061 161 I NG A TGI A AGYAT N IPPHNL N EVIDA LI Y R IDHP NCSV DKLME IVK GPDFPTG G IIQG E D G I S KAYETGKG KFII R A K I E 240
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9230561 244 IE KL K G G KE QIVITEIPYE I NKAN L VKKI DDVRVN NKVAGI A EVRDESDR D G L RI A IELKKDAN T E LV LN Y LFK Y TDLQI 323
Cdd:TIGR01061 241 IE VN K N G LN QIVITEIPYE T NKAN I VKKI EEIIFD NKVAGI E EVRDESDR N G I RI I IELKKDAN A E KI LN F LFK H TDLQI 320
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9230561 324 NYNFNMVAI D N F TP R QVG IVPI L SS YI A H RR EVI LA RS PFDK EKA E KRL R IVEGLI RV ISI L DE V I A LIR A SE N K A D P KE 403
Cdd:TIGR01061 321 NYNFNMVAI A N R TP I QVG LLSY L DA YI K H CH EVI IN RS KYEL EKA S KRL E IVEGLI KA ISI I DE I I K LIR S SE D K S D A KE 400
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9230561 404 NL KVSYD FTE E QAEAIV T L Q LYRLTNTD VVV L Q EE EA EL RE KI AM L AA II GD E RTMYN L M KK E L R E V KK N FA TP R L S SL E 483
Cdd:TIGR01061 401 NL IDNFK FTE N QAEAIV S L R LYRLTNTD IFE L K EE QN EL EK KI IS L EQ II AS E KARNK L L KK Q L E E Y KK Q FA QQ R R S QI E 480
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9230561 484 D TAKA I E I DTAS LI AE ED T YV SV TKAGYIKRTS P RSFA A S TLEEI G KR DDD R L IFVQS A K TT QHL L M FTSLGN V I YR P I H 563
Cdd:TIGR01061 481 D FINQ I K I NESE LI EN ED Y YV LI TKAGYIKRTS N RSFA S S KYTDF G SK DDD I L FAQTI A N TT DQI L I FTSLGN I I NI P V H 560
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9230561 564 E LADIRWKD I GEHLS QT IT n F ET NE A I LY V EVLDQ FD - D ATTYFA A TR LG QI KR V E RK E FTPW R T yr SK SVKYA KLKD DT 642
Cdd:TIGR01061 561 K LADIRWKD L GEHLS NK IT - F DE NE T I VF V GTMNE FD v D QPILVL A SK LG MV KR I E LT E LNIK R N -- SK ATLCI KLKD KD 637
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9230561 643 DQ I V A VAPI K LDDVV LVS QN GYAL R F NIE E V PVVGAKAAGVK A M N LKEDD VLQ SG F I CNTS - S FY LLTQRGS L KR V SI E E 721
Cdd:TIGR01061 638 HL I S A FLQQ K DKLIC LVS DL GYAL V F HTN E I PVVGAKAAGVK G M K LKEDD QVK SG V I FEAN e S LV LLTQRGS V KR L SI S E 717
730 740
....*....|....*....|..
gi 9230561 722 ILA TSRA KR G LQV L r E LK N KPH 743
Cdd:TIGR01061 718 LVV TSRA AT G KKL L - P LK K KPH 738
GyrA
COG0188 DNA gyrase/topoisomerase IV, subunit A [Replication, recombination and repair];
2-810
0e+00
DNA gyrase/topoisomerase IV, subunit A [Replication, recombination and repair];
Pssm-ID: 439958 [Multi-domain]
Cd Length: 804
Bit Score: 1073.13
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9230561 2 SN I QNMS LED I M GERFGR Y SKYI I QD RALPD I RDGLKPV Q RRILY S M NKDSN T F DK S Y R KSA KS VG NI MG NF HPHGDS SI 81
Cdd:COG0188 8 ER I IPVN LED E M KRSYLD Y AMSV I VG RALPD V RDGLKPV H RRILY A M HELGL T P DK P Y K KSA RV VG DV MG KY HPHGDS AV 87
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9230561 82 YDA M VRM S Q NWKN R EI LV EMH GN N GS M DGDP P AAMRYTEARL SE IA GY LL Q DI E K K TV P F AW N F D DT E K EPTVLPA A FPN 161
Cdd:COG0188 88 YDA L VRM A Q DFSM R YP LV DGQ GN F GS I DGDP A AAMRYTEARL AK IA EE LL A DI D K D TV D F VP N Y D GS E Q EPTVLPA R FPN 167
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9230561 162 LLVNGS T GI SA G Y AT D IPPHNL A EVIDA AVYM ID H P T A K I DK LME FL PGPDFPTG A II Q GR DE I KK AYETG K G RVV VR S K 241
Cdd:COG0188 168 LLVNGS S GI AV G M AT N IPPHNL G EVIDA CIAL ID N P D A T I EE LME YI PGPDFPTG G II V GR EG I RE AYETG R G SIR VR A K 247
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9230561 242 T EIE K LK G G K EQIV I TEIPY EI NKA N L VK KI DDVRVNN K VA GI AE VRDESDRDG L RI A IELK K DAN T E L VLN Y L F K Y T D L 321
Cdd:COG0188 248 A EIE E LK R G R EQIV V TEIPY QV NKA R L IE KI AELVKEK K IE GI SD VRDESDRDG M RI V IELK R DAN P E V VLN Q L Y K H T Q L 327
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9230561 322 Q INYNF NM V A IDNFT PR QVGIVP IL SSYIA HRREV ILA R SP F DKE KAE K R LR I V EGL IRVISIL DEVIA L IRAS ENKADP 401
Cdd:COG0188 328 Q TSFGI NM L A LVDGR PR VLNLKE IL EAFLD HRREV VTR R TQ F ELR KAE E R AH I L EGL LIALDNI DEVIA I IRAS KDPDEA 407
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9230561 402 KE N L KVSYDFT E E QAEAI VTLQ L Y RLT NTDVVVLQE E E AEL REK IA M L AA I IGD E RTMYNLM K K EL R E V KK NFATP R LSS 481
Cdd:COG0188 408 KE A L MERFGLS E I QAEAI LDMR L R RLT GLEREKIED E Y AEL LKE IA E L ED I LAS E ERLLKII K E EL L E I KK KYGDE R RTE 487
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9230561 482 L E DTAK ai EID TAS LI AE ED TY V SVTKA GYIKRT SPRSFA A ST ----- LEEI G KRDD D RLIFVQS A K T TQH LL M FT SL G N 556
Cdd:COG0188 488 I E EAEG -- EID IED LI PD ED VV V TLSHK GYIKRT PLDTYR A QR rggkg VSGM G TKEE D FVEHLFV A S T HDT LL F FT NK G R 565
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9230561 557 V IYRPIH EL ADIRWKDI G EHLSQTI t NF E TN E A I LY V EVLDQ FD DATTYFA AT RL G QI K RVERKE F TPW rty R SKSVKYA 636
Cdd:COG0188 566 V YRLKVY EL PEGSRTAK G KPIVNLL - PL E PG E K I TA V LPVKE FD EDKYLLF AT KK G TV K KTPLSD F SNI --- R KNGIIAI 641
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9230561 637 K LK DD t D QI V A VA PIK - L DDV V L VSQ NG Y A L RF NIEE V PVV G AK A A GV KAMN LKE D D VLQSGFICNTSSFY L L - T QR G SL 714
Cdd:COG0188 642 N LK EG - D EL V G VA LTD g D DDV L L ATS NG K A I RF PESD V RPM G RT A R GV RGIR LKE G D EVVGMAVVDEEDDL L T v T EN G YG 720
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9230561 715 KR VSIE E ILATS R AKR G LQVLRELKNKPH rvf L A GA VA eqgfvgdffste V DVN D QTL L V q SNK G TIYESRLQ D LNLSE R 794
Cdd:COG0188 721 KR TPLS E YRLQG R GGK G VITIKLTEKNGK --- L V GA LV ------------ V NDD D ELM L I - TSS G QLIRTPVS D IRVTG R 784
810
....*....|....*.
gi 9230561 795 TSN G SFISDTISDEE V 810
Cdd:COG0188 785 NTQ G VRLIRLDEGDK V 800
PRK05561
PRK05561 DNA topoisomerase 4 subunit A;
1-744
0e+00
DNA topoisomerase 4 subunit A;
Pssm-ID: 235503 [Multi-domain]
Cd Length: 742
Bit Score: 1067.80
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9230561 1 MSN I QNMS LE DIMG ER FG RY SK Y I I Q DRALPD I RDGLKPVQRRILY S M NKDSN T F D KSYR KSA KS VG NIM G NF HPHGDSS 80
Cdd:PRK05561 7 LEG I EDLP LE EFLE ER YL RY AM Y V I M DRALPD V RDGLKPVQRRILY A M SELGL T P D AKFK KSA RV VG DVL G KY HPHGDSS 86
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9230561 81 IYDAMVRM S Q NWKN R EI LV EMH GN N GS M DGDP P AAMRYTEARLS E IA GY LL QD I EKK TV P F AW NFD D T E KEPTVLPA A FP 160
Cdd:PRK05561 87 IYDAMVRM A Q DFSY R YP LV DGQ GN F GS I DGDP A AAMRYTEARLS P IA EL LL EE I DEG TV D F VP NFD G T L KEPTVLPA R FP 166
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9230561 161 NLL V NG S TGI SA G Y ATDIPPHNL A EVIDAA VYM ID H P T A KIDK LMEF L PGPDFPTG A - II Q GRD E I K KAYETG K G RVV VR 239
Cdd:PRK05561 167 NLL L NG A TGI AV G M ATDIPPHNL R EVIDAA IHL ID N P D A TLEE LMEF V PGPDFPTG G e II T GRD G I R KAYETG R G SIR VR 246
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9230561 240 SKT EIE K L K GG KE QIVITE I PY EIN KA N L VKK I DDVRVNN K VA GIA E VRDESDR DG - L RI A IE L K KD - ANT E LVL N Y LF K 317
Cdd:PRK05561 247 ARW EIE D L A GG RW QIVITE L PY QVS KA K L IEQ I AELMNAK K LP GIA D VRDESDR EN p V RI V IE P K SN r VDP E ALM N H LF A 326
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9230561 318 Y TDL QIN Y NF NM V AI D - NFT PR QV G IVP ILS SYIA HRREV ILA RS P F DKE K A EKRL R I V EGL IRVISIL DEVI AL IR A S E 396
Cdd:PRK05561 327 T TDL ESS Y RV NM N AI G l DGR PR VK G LKE ILS EWLD HRREV VTR RS Q F RLD K V EKRL H I L EGL LIAFLNI DEVI RI IR E S D 406
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9230561 397 nka D PK E NL KVSY D FT E E QAEAI VT L Q L Y RL TNTDVVVLQE E EA ELR EK IA M L A AI IGD ER TMYN L M KKEL REVK K N F AT 476
Cdd:PRK05561 407 --- E PK A NL MARF D LS E I QAEAI LE L R L R RL AKLEEIEIRK E QD ELR KE IA E L E AI LAS ER KLRK L I KKEL KADA K K F GD 483
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9230561 477 PR LSSL E DTAK AI E ID TAS LI AE E DTY V SVT K A G YIK R TSPR S FA AS T L eei GKRDD D R L I F VQS A K TT QH LL M FTS L G N 556
Cdd:PRK05561 484 PR RTPI E EAEE AI A ID EEA LI PD E PVT V VLS K K G WVR R AKGH S ID AS G L --- SFKEG D S L L F AFE A R TT DK LL L FTS T G R 560
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9230561 557 V IYR P I HEL ADI R w K D i GE H L SQTI t NFETN E A I LY V EV ldq FD DATTYFA A TRL G QIKR V ERKE f TPW RT YRS K S V KYA 636
Cdd:PRK05561 561 V YSL P V HEL PSA R - G D - GE P L TGLV - DLAPG E E I VH V LA --- FD PDQKLLL A SSA G YGFV V TLED - LVA RT RAG K A V INL 633
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9230561 637 K lkd D T D QIVAVA P IKL - D DVVLVSQ NG YA L R F NIE E V P VV G a K AA GVK AM NL K - E DD V L QSGFIC N T - SSFY LLT Q - RG 712
Cdd:PRK05561 634 K --- D G D EVLPPV P VED d D HLAAITS NG RL L V F PLS E L P EL G - K GK GVK LI NL P k D DD G L VDLRVL N P e DGLV LLT A g KR 709
730 740 750
....*....|....*....|....*....|...
gi 9230561 713 S LK RVSI E - E ILATS RA K RG LQVL R E LK NK P HR 744
Cdd:PRK05561 710 K LK LKPS E l E KYRGK RA R RG RLLP R G LK RV P RF 742
TOP4c
cd00187 DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), ...
26-470
0e+00
DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes in DNA topology by catalysing the concerted breakage and rejoining of DNA strands during normal cellular growth.
Pssm-ID: 238111 [Multi-domain]
Cd Length: 445
Bit Score: 644.24
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9230561 26 QD RALPD I RDGLKPVQRRILY S M N K DSN T F DK SYR K S A KS VG NIM G NF HPHGDSS I YD AM VRM S Q NWK N REI L VEMH GN N 105
Cdd:cd00187 1 NG RALPD V RDGLKPVQRRILY A M F K RGL T P DK PEK K V A RL VG DVA G KY HPHGDSS L YD TI VRM A Q DFS N NIP L LDPQ GN F 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9230561 106 GS M DGD PP AAMRYTE A RLS E IA GY LL Q DI EKK TV P F AW N F D DT E K EP T VLP AA FPNLLVNGS T GI SA G Y AT D IPPHNL A E 185
Cdd:cd00187 81 GS R DGD DA AAMRYTE T RLS P IA RL LL P DI DDP TV D F VP N Y D GQ E V EP E VLP PI FPNLLVNGS S GI AV G M AT N IPPHNL R E 160
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9230561 186 VIDA AVYM ID H P T A K ID K LME FLP GPDFPTG A II Q GR DE I KK AYETG K GR VVV R S K T EIE KLK g G KEQ I V ITE I PY EI NK 265
Cdd:cd00187 161 VIDA LRAL ID N P E A S ID E LME IIK GPDFPTG G II E GR AG I RE AYETG R GR YII R G K Y EIE DDE - G RNT I E ITE L PY QV NK 239
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9230561 266 A N L VK KI DDVRVNN K VA GI AE VRDESDR D G L R IA IELK KD A NT E L VLN Y L F K Y T D LQ INYNF NMVA I D - N FT P RQVGIVP 344
Cdd:cd00187 240 A K L KE KI AELVKDK K IE GI SD VRDESDR E G I R FV IELK RG A MA E V VLN G L Y K V T K LQ TTFGI NMVA F D p N GR P KKLNLKE 319
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9230561 345 IL SSYIA HR R EV ILA R SPFDKE KAE K RL R I V EGL IRV I SIL DEVI A LIR A S E nka DP K EN L K --- VSYD F T E E QA E AI VT 421
Cdd:cd00187 320 IL QEFLD HR L EV YTR R KEYELG KAE A RL H I L EGL LKA I LNI DEVI N LIR S S D --- EA K KA L I eel EKLG F S E I QA D AI LD 396
410 420 430 440
....*....|....*....|....*....|....*....|....*....
gi 9230561 422 LQ L Y RLT NTDVVV L QE E EA EL REK I AM L AA I IGD E RTMYN L M K K EL R E V 470
Cdd:cd00187 397 MR L R RLT KLEREK L LK E LK EL EAE I ED L EK I LAS E ERPKD L W K E EL D E F 445
DNA_topoisoIV
pfam00521 DNA gyrase/topoisomerase IV, subunit A;
28-468
0e+00
DNA gyrase/topoisomerase IV, subunit A;
Pssm-ID: 459843 [Multi-domain]
Cd Length: 432
Bit Score: 608.01
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9230561 28 RA L PD I RDGLKPVQRRILY S M NK d SNTF DK S Y R K S A KS VG NI MG NF HPHGD S S I YDA M VRM S Q NWKNREI L VEMH GN N GS 107
Cdd:pfam00521 1 RA I PD V RDGLKPVQRRILY A M FE - LLNL DK P Y K K V A RL VG DV MG KY HPHGD A S L YDA I VRM A Q DFVGNIP L LDGQ GN F GS 79
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9230561 108 - M DGD PP AAMRYTE A RLS E IA GY L LQ DI EKK TV PFAW N F D D TE K EPTVLP AAF PNLLVNG ST GI SA G Y AT D IPPHNL A E V 186
Cdd:pfam00521 80 r I DGD KD AAMRYTE T RLS K IA RE L FP DI DDD TV DYVP N Y D G TE V EPTVLP PII PNLLVNG AE GI AV G M AT N IPPHNL R E I 159
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9230561 187 IDA AVYMI D H P T A KI dk LM EFLP GPDFPTG AI I Q G RDE IK K AY E TG K G RVV VR S K T EIE K lkgg KEQ IVITE I PY EINKA 266
Cdd:pfam00521 160 IDA LIALL D G P E A TL -- LM KYIM GPDFPTG GG I I G KGG IK E AY K TG R G KIT VR A K V EIE D ---- RKT IVITE L PY GVWTS 233
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9230561 267 N L VK KI DDVRV N N K VA GI AEV RDESDR d G L RI A IELK KD A NT E L VLN Y L F K Y T D LQ INYNF N MVAIDNFT P RQV G IVP IL 346
Cdd:pfam00521 234 D L IE KI EELVK N G K IK GI SDI RDESDR - G V RI V IELK RG A DP E V VLN D L Y K K T K LQ TSFST N NLVLFDGG P KYL G LKE IL 312
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9230561 347 SSYIA HR R EV ILA R SPFDK EK A E K RL R I V EGL IRVISIL D E VI AL IR A S ENKADP K E NL KV sy DFT E E QA EAIVTLQ L Y R 426
Cdd:pfam00521 313 KEFLD HR L EV YER R KEYLL EK L E E RL H I L EGL LIALNNI D F VI EI IR G S IDRKKA K K NL IE -- ELS E I QA DYLLDMR L R R 390
410 420 430 440
....*....|....*....|....*....|....*....|..
gi 9230561 427 LT NTD V VV L Q EE EA EL REK IA M L AAIIGD E RTMYN L MKK EL R 468
Cdd:pfam00521 391 LT KEE V DK L L EE ID EL EKE IA E L EKLLAS E KKLND L WIE EL D 432
TOP4c
smart00434 DNA Topoisomerase IV; Bacterial DNA topoisomerase IV, GyrA, ParC
7-459
0e+00
DNA Topoisomerase IV; Bacterial DNA topoisomerase IV, GyrA, ParC
Pssm-ID: 214660 [Multi-domain]
Cd Length: 444
Bit Score: 580.29
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9230561 7 MSL ED IMGERFGR YS KYI I QD RA L PD I RDGLKPVQRRILY S M N K DSN T F D KSYR KSA KS VG NI MG NF HPHGDSS I YD AM V 86
Cdd:smart00434 1 IDI ED FINKEYLD YS MSV I NG RA I PD V RDGLKPVQRRILY A M F K RGL T P D EPKV KSA RG VG DV MG KY HPHGDSS L YD TI V 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9230561 87 RM S Q NWK N REI L VEMH GN N GS M - DGD PP AAMRYTE A RLS EI A GY LL Q DI E K K TV P F AW N F D DT E K EPTVLP AAF PNLLVN 165
Cdd:smart00434 81 RM A Q DFS N NYP L LDGQ GN F GS R l DGD DA AAMRYTE T RLS PL A RL LL P DI D K D TV D F VP N Y D GQ E I EPTVLP PII PNLLVN 160
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9230561 166 GS T GI SA G Y AT D IPPHNL A EVIDA AVYM ID H P T A K ID K LM EFLP GPDFPTG AI I Q G RD eikkayetgkg RV VVR S K T EIE 245
Cdd:smart00434 161 GS S GI AV G M AT N IPPHNL R EVIDA VRRL ID N P D A S ID E LM MIPW GPDFPTG GE I V G PG ----------- KY VVR G K I EIE 229
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9230561 246 KLK ggke Q IVITE I PY EI N K A N L VK KI DDVRVNN K VA GI AE VRDES - DR D G L RI A IELK KD A NT E L VLN Y L F K Y T D LQ IN 324
Cdd:smart00434 230 DDN ---- T IVITE L PY QV N T A D L IE KI AELVKDK K IE GI ID VRDES h DR T G V RI V IELK RG A MA E V VLN G L Y K L T K LQ TT 305
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9230561 325 YNF NM V A I - DN FT P RQVGIVP IL SSYIA HR R EV ILA R SPFDKE K A E - K RL R I V EGL IRVI SI L DE V I A LIR A S ENK A - DP 401
Cdd:smart00434 306 FSI NM L A L f DN GR P KKYNLKE IL KEFLD HR L EV YTR R KEYLLG K L E a E RL H I L EGL FIAL SI I DE I I V LIR S S KDL A k EA 385
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|....*...
gi 9230561 402 KE N L KVSYDFT E E QA E AI VTLQ L Y RLT NTD V VV L QE E EA EL REK I AM L AA I IGD E RTM 459
Cdd:smart00434 386 KE K L MERFELS E I QA D AI LDMR L R RLT KLE V EK L EK E LK EL EKE I ED L EK I LAS E EWL 443
Name
Accession
Description
Interval
E-value
parC_Gpos
TIGR01061 DNA topoisomerase IV, A subunit, Gram-positive; Operationally, topoisomerase IV is a type II ...
4-743
0e+00
DNA topoisomerase IV, A subunit, Gram-positive; Operationally, topoisomerase IV is a type II topoisomerase required for the decatenation of chromosome segregation. Not every bacterium has both a topo II and a topo IV. The topo IV families of the Gram-positive bacteria and the Gram-negative bacteria appear not to represent a single clade among the type II topoisomerases, and are represented by separate models for this reason. [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 273422 [Multi-domain]
Cd Length: 738
Bit Score: 1247.77
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9230561 4 I Q N MS LE DIM GE R FG R Y S KYIIQDRALPDIRDGLKPVQRRILY S M NK D S NTFDK S Y R KSA KS VG N IMG NF HPHGDSSIYD 83
Cdd:TIGR01061 1 I F N KP LE EVF GE S FG K Y A KYIIQDRALPDIRDGLKPVQRRILY A M FQ D G NTFDK P Y K KSA RT VG E IMG KY HPHGDSSIYD 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9230561 84 AMVRMSQ N WKN REI LVEMHGNNGS M DGD PP AAMRYTEARLS E IA GY LL Q DI E KKTV P F AW NFDD T EKEPTVLPA A FPNLL 163
Cdd:TIGR01061 81 AMVRMSQ D WKN NWT LVEMHGNNGS I DGD NA AAMRYTEARLS L IA SE LL K DI D KKTV S F IP NFDD S EKEPTVLPA L FPNLL 160
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9230561 164 V NG S TGI S AGYAT D IPPHNL A EVIDA AV Y M IDHP TAKI DKLME FLP GPDFPTG A IIQG R D E I K KAYETGKG RVVV R S K T E 243
Cdd:TIGR01061 161 I NG A TGI A AGYAT N IPPHNL N EVIDA LI Y R IDHP NCSV DKLME IVK GPDFPTG G IIQG E D G I S KAYETGKG KFII R A K I E 240
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9230561 244 IE KL K G G KE QIVITEIPYE I NKAN L VKKI DDVRVN NKVAGI A EVRDESDR D G L RI A IELKKDAN T E LV LN Y LFK Y TDLQI 323
Cdd:TIGR01061 241 IE VN K N G LN QIVITEIPYE T NKAN I VKKI EEIIFD NKVAGI E EVRDESDR N G I RI I IELKKDAN A E KI LN F LFK H TDLQI 320
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9230561 324 NYNFNMVAI D N F TP R QVG IVPI L SS YI A H RR EVI LA RS PFDK EKA E KRL R IVEGLI RV ISI L DE V I A LIR A SE N K A D P KE 403
Cdd:TIGR01061 321 NYNFNMVAI A N R TP I QVG LLSY L DA YI K H CH EVI IN RS KYEL EKA S KRL E IVEGLI KA ISI I DE I I K LIR S SE D K S D A KE 400
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9230561 404 NL KVSYD FTE E QAEAIV T L Q LYRLTNTD VVV L Q EE EA EL RE KI AM L AA II GD E RTMYN L M KK E L R E V KK N FA TP R L S SL E 483
Cdd:TIGR01061 401 NL IDNFK FTE N QAEAIV S L R LYRLTNTD IFE L K EE QN EL EK KI IS L EQ II AS E KARNK L L KK Q L E E Y KK Q FA QQ R R S QI E 480
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9230561 484 D TAKA I E I DTAS LI AE ED T YV SV TKAGYIKRTS P RSFA A S TLEEI G KR DDD R L IFVQS A K TT QHL L M FTSLGN V I YR P I H 563
Cdd:TIGR01061 481 D FINQ I K I NESE LI EN ED Y YV LI TKAGYIKRTS N RSFA S S KYTDF G SK DDD I L FAQTI A N TT DQI L I FTSLGN I I NI P V H 560
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9230561 564 E LADIRWKD I GEHLS QT IT n F ET NE A I LY V EVLDQ FD - D ATTYFA A TR LG QI KR V E RK E FTPW R T yr SK SVKYA KLKD DT 642
Cdd:TIGR01061 561 K LADIRWKD L GEHLS NK IT - F DE NE T I VF V GTMNE FD v D QPILVL A SK LG MV KR I E LT E LNIK R N -- SK ATLCI KLKD KD 637
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9230561 643 DQ I V A VAPI K LDDVV LVS QN GYAL R F NIE E V PVVGAKAAGVK A M N LKEDD VLQ SG F I CNTS - S FY LLTQRGS L KR V SI E E 721
Cdd:TIGR01061 638 HL I S A FLQQ K DKLIC LVS DL GYAL V F HTN E I PVVGAKAAGVK G M K LKEDD QVK SG V I FEAN e S LV LLTQRGS V KR L SI S E 717
730 740
....*....|....*....|..
gi 9230561 722 ILA TSRA KR G LQV L r E LK N KPH 743
Cdd:TIGR01061 718 LVV TSRA AT G KKL L - P LK K KPH 738
GyrA
COG0188 DNA gyrase/topoisomerase IV, subunit A [Replication, recombination and repair];
2-810
0e+00
DNA gyrase/topoisomerase IV, subunit A [Replication, recombination and repair];
Pssm-ID: 439958 [Multi-domain]
Cd Length: 804
Bit Score: 1073.13
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9230561 2 SN I QNMS LED I M GERFGR Y SKYI I QD RALPD I RDGLKPV Q RRILY S M NKDSN T F DK S Y R KSA KS VG NI MG NF HPHGDS SI 81
Cdd:COG0188 8 ER I IPVN LED E M KRSYLD Y AMSV I VG RALPD V RDGLKPV H RRILY A M HELGL T P DK P Y K KSA RV VG DV MG KY HPHGDS AV 87
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9230561 82 YDA M VRM S Q NWKN R EI LV EMH GN N GS M DGDP P AAMRYTEARL SE IA GY LL Q DI E K K TV P F AW N F D DT E K EPTVLPA A FPN 161
Cdd:COG0188 88 YDA L VRM A Q DFSM R YP LV DGQ GN F GS I DGDP A AAMRYTEARL AK IA EE LL A DI D K D TV D F VP N Y D GS E Q EPTVLPA R FPN 167
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9230561 162 LLVNGS T GI SA G Y AT D IPPHNL A EVIDA AVYM ID H P T A K I DK LME FL PGPDFPTG A II Q GR DE I KK AYETG K G RVV VR S K 241
Cdd:COG0188 168 LLVNGS S GI AV G M AT N IPPHNL G EVIDA CIAL ID N P D A T I EE LME YI PGPDFPTG G II V GR EG I RE AYETG R G SIR VR A K 247
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9230561 242 T EIE K LK G G K EQIV I TEIPY EI NKA N L VK KI DDVRVNN K VA GI AE VRDESDRDG L RI A IELK K DAN T E L VLN Y L F K Y T D L 321
Cdd:COG0188 248 A EIE E LK R G R EQIV V TEIPY QV NKA R L IE KI AELVKEK K IE GI SD VRDESDRDG M RI V IELK R DAN P E V VLN Q L Y K H T Q L 327
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9230561 322 Q INYNF NM V A IDNFT PR QVGIVP IL SSYIA HRREV ILA R SP F DKE KAE K R LR I V EGL IRVISIL DEVIA L IRAS ENKADP 401
Cdd:COG0188 328 Q TSFGI NM L A LVDGR PR VLNLKE IL EAFLD HRREV VTR R TQ F ELR KAE E R AH I L EGL LIALDNI DEVIA I IRAS KDPDEA 407
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9230561 402 KE N L KVSYDFT E E QAEAI VTLQ L Y RLT NTDVVVLQE E E AEL REK IA M L AA I IGD E RTMYNLM K K EL R E V KK NFATP R LSS 481
Cdd:COG0188 408 KE A L MERFGLS E I QAEAI LDMR L R RLT GLEREKIED E Y AEL LKE IA E L ED I LAS E ERLLKII K E EL L E I KK KYGDE R RTE 487
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9230561 482 L E DTAK ai EID TAS LI AE ED TY V SVTKA GYIKRT SPRSFA A ST ----- LEEI G KRDD D RLIFVQS A K T TQH LL M FT SL G N 556
Cdd:COG0188 488 I E EAEG -- EID IED LI PD ED VV V TLSHK GYIKRT PLDTYR A QR rggkg VSGM G TKEE D FVEHLFV A S T HDT LL F FT NK G R 565
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9230561 557 V IYRPIH EL ADIRWKDI G EHLSQTI t NF E TN E A I LY V EVLDQ FD DATTYFA AT RL G QI K RVERKE F TPW rty R SKSVKYA 636
Cdd:COG0188 566 V YRLKVY EL PEGSRTAK G KPIVNLL - PL E PG E K I TA V LPVKE FD EDKYLLF AT KK G TV K KTPLSD F SNI --- R KNGIIAI 641
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9230561 637 K LK DD t D QI V A VA PIK - L DDV V L VSQ NG Y A L RF NIEE V PVV G AK A A GV KAMN LKE D D VLQSGFICNTSSFY L L - T QR G SL 714
Cdd:COG0188 642 N LK EG - D EL V G VA LTD g D DDV L L ATS NG K A I RF PESD V RPM G RT A R GV RGIR LKE G D EVVGMAVVDEEDDL L T v T EN G YG 720
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9230561 715 KR VSIE E ILATS R AKR G LQVLRELKNKPH rvf L A GA VA eqgfvgdffste V DVN D QTL L V q SNK G TIYESRLQ D LNLSE R 794
Cdd:COG0188 721 KR TPLS E YRLQG R GGK G VITIKLTEKNGK --- L V GA LV ------------ V NDD D ELM L I - TSS G QLIRTPVS D IRVTG R 784
810
....*....|....*.
gi 9230561 795 TSN G SFISDTISDEE V 810
Cdd:COG0188 785 NTQ G VRLIRLDEGDK V 800
PRK05561
PRK05561 DNA topoisomerase 4 subunit A;
1-744
0e+00
DNA topoisomerase 4 subunit A;
Pssm-ID: 235503 [Multi-domain]
Cd Length: 742
Bit Score: 1067.80
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9230561 1 MSN I QNMS LE DIMG ER FG RY SK Y I I Q DRALPD I RDGLKPVQRRILY S M NKDSN T F D KSYR KSA KS VG NIM G NF HPHGDSS 80
Cdd:PRK05561 7 LEG I EDLP LE EFLE ER YL RY AM Y V I M DRALPD V RDGLKPVQRRILY A M SELGL T P D AKFK KSA RV VG DVL G KY HPHGDSS 86
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9230561 81 IYDAMVRM S Q NWKN R EI LV EMH GN N GS M DGDP P AAMRYTEARLS E IA GY LL QD I EKK TV P F AW NFD D T E KEPTVLPA A FP 160
Cdd:PRK05561 87 IYDAMVRM A Q DFSY R YP LV DGQ GN F GS I DGDP A AAMRYTEARLS P IA EL LL EE I DEG TV D F VP NFD G T L KEPTVLPA R FP 166
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9230561 161 NLL V NG S TGI SA G Y ATDIPPHNL A EVIDAA VYM ID H P T A KIDK LMEF L PGPDFPTG A - II Q GRD E I K KAYETG K G RVV VR 239
Cdd:PRK05561 167 NLL L NG A TGI AV G M ATDIPPHNL R EVIDAA IHL ID N P D A TLEE LMEF V PGPDFPTG G e II T GRD G I R KAYETG R G SIR VR 246
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9230561 240 SKT EIE K L K GG KE QIVITE I PY EIN KA N L VKK I DDVRVNN K VA GIA E VRDESDR DG - L RI A IE L K KD - ANT E LVL N Y LF K 317
Cdd:PRK05561 247 ARW EIE D L A GG RW QIVITE L PY QVS KA K L IEQ I AELMNAK K LP GIA D VRDESDR EN p V RI V IE P K SN r VDP E ALM N H LF A 326
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9230561 318 Y TDL QIN Y NF NM V AI D - NFT PR QV G IVP ILS SYIA HRREV ILA RS P F DKE K A EKRL R I V EGL IRVISIL DEVI AL IR A S E 396
Cdd:PRK05561 327 T TDL ESS Y RV NM N AI G l DGR PR VK G LKE ILS EWLD HRREV VTR RS Q F RLD K V EKRL H I L EGL LIAFLNI DEVI RI IR E S D 406
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9230561 397 nka D PK E NL KVSY D FT E E QAEAI VT L Q L Y RL TNTDVVVLQE E EA ELR EK IA M L A AI IGD ER TMYN L M KKEL REVK K N F AT 476
Cdd:PRK05561 407 --- E PK A NL MARF D LS E I QAEAI LE L R L R RL AKLEEIEIRK E QD ELR KE IA E L E AI LAS ER KLRK L I KKEL KADA K K F GD 483
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9230561 477 PR LSSL E DTAK AI E ID TAS LI AE E DTY V SVT K A G YIK R TSPR S FA AS T L eei GKRDD D R L I F VQS A K TT QH LL M FTS L G N 556
Cdd:PRK05561 484 PR RTPI E EAEE AI A ID EEA LI PD E PVT V VLS K K G WVR R AKGH S ID AS G L --- SFKEG D S L L F AFE A R TT DK LL L FTS T G R 560
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9230561 557 V IYR P I HEL ADI R w K D i GE H L SQTI t NFETN E A I LY V EV ldq FD DATTYFA A TRL G QIKR V ERKE f TPW RT YRS K S V KYA 636
Cdd:PRK05561 561 V YSL P V HEL PSA R - G D - GE P L TGLV - DLAPG E E I VH V LA --- FD PDQKLLL A SSA G YGFV V TLED - LVA RT RAG K A V INL 633
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9230561 637 K lkd D T D QIVAVA P IKL - D DVVLVSQ NG YA L R F NIE E V P VV G a K AA GVK AM NL K - E DD V L QSGFIC N T - SSFY LLT Q - RG 712
Cdd:PRK05561 634 K --- D G D EVLPPV P VED d D HLAAITS NG RL L V F PLS E L P EL G - K GK GVK LI NL P k D DD G L VDLRVL N P e DGLV LLT A g KR 709
730 740 750
....*....|....*....|....*....|...
gi 9230561 713 S LK RVSI E - E ILATS RA K RG LQVL R E LK NK P HR 744
Cdd:PRK05561 710 K LK LKPS E l E KYRGK RA R RG RLLP R G LK RV P RF 742
PRK05560
PRK05560 DNA gyrase subunit A; Validated
1-798
0e+00
DNA gyrase subunit A; Validated
Pssm-ID: 235502 [Multi-domain]
Cd Length: 805
Bit Score: 827.75
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9230561 1 MSN I QNMSL ED I M GERFGR Y SKYI I QD RALPD I RDGLKPV Q RRILY S MN KDS NT F DK S Y R KSA KS VG NI MG NF HPHGDS S 80
Cdd:PRK05560 2 GDR I IPVNI ED E M KRSYLD Y AMSV I VG RALPD V RDGLKPV H RRILY A MN ELG NT P DK P Y K KSA RI VG DV MG KY HPHGDS A 81
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9230561 81 I YDA M VRM S Q NWKN R EI LV EMH GN N GS M DGDP P AAMRYTEAR L S E IA GY LL Q DI E K K TV P F AW N F D DT E K EPTVLPA A FP 160
Cdd:PRK05560 82 V YDA L VRM A Q DFSM R YP LV DGQ GN F GS I DGDP A AAMRYTEAR M S K IA HE LL A DI D K E TV D F VP N Y D GS E Q EPTVLPA R FP 161
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9230561 161 NLLVNGS T GI SA G Y AT D IPPHNL A EVIDA AVYM ID H P TAK I DK LME FL PGPDFPTG A II Q GR DE I KK AY E TG K G RV V V R S 240
Cdd:PRK05560 162 NLLVNGS S GI AV G M AT N IPPHNL G EVIDA CLAL ID N P DIT I EE LME II PGPDFPTG G II L GR SG I RE AY R TG R G SI V M R A 241
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9230561 241 K T EIE KL K g G K E Q I VI TEIPY EI NKA N L VK KI - DD V R v NN K VA GI AEV RDESDRDG L RI A IELK K DA NT E L VLN Y L F K Y T 319
Cdd:PRK05560 242 K A EIE EI K - G R E A I IV TEIPY QV NKA R L IE KI a EL V K - EK K IE GI SDL RDESDRDG M RI V IELK R DA VP E V VLN N L Y K H T 319
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9230561 320 D LQ INYNF NM V A IDNFT P RQVGIVP IL SSYIA HR R EVI LA R SP F DKE KAE K R LR I V EGL IRVISIL DEVIALIRAS ENK A 399
Cdd:PRK05560 320 Q LQ TSFGI NM L A LVDGQ P KLLNLKE IL EAFLE HR K EVI TR R TR F ELR KAE E R AH I L EGL LIALDNI DEVIALIRAS PTP A 399
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9230561 400 DP KE N L KVSYDFT E E QA E AI VTLQ L Y RLT NTDVVVLQE E EA EL REK IA M L AA I IGDERTMYNLM K K EL R E V K KN F AT PR L 479
Cdd:PRK05560 400 EA KE G L MERFGLS E I QA Q AI LDMR L Q RLT GLERDKIED E YK EL LAL IA D L KD I LASPERLLEII K E EL L E I K EK F GD PR R 479
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9230561 480 SSLED ta KAIE ID TAS LI A EED TY V SV T KA GYIKRT SPRSF ----------- A A S T leeigk RD DD RL -- I FV qs A K T TQ 546
Cdd:PRK05560 480 TEIIE -- GEGD ID DED LI P EED VV V TL T HG GYIKRT PLDEY raqrrggkgvs G A K T ------ KE DD FV eh L FV -- A S T HD 549
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9230561 547 H LL M FT SL G N V i YR - PIH E LADIRWKDI G EHLSQTI t NF E TN E A I LYVEVLDQ FDD ATTY F A AT RL G QI K RVERK EF T pw 625
Cdd:PRK05560 550 T LL F FT NR G R V - YR l KVY E IPEASRTAR G RPIVNLL - PL E PG E K I TAILPVRE FDD DKYL F F AT KN G TV K KTSLS EF S -- 625
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9230561 626 r TY RS KSVKYAK L KDD t D QIVA V APIK - L DD VV L VSQ NG Y A L RF NIEE V PVV G AK A A GV KAMN L K E D D VLQ S GFICNTS S 704
Cdd:PRK05560 626 - NI RS NGIIAIN L DEG - D ELIG V RLTD g D DD IL L ATK NG K A I RF PESD V RPM G RT A R GV RGIK L R E G D EVV S MDVVRED S 703
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9230561 705 FYL L -- T QR G SL KR VSIE E ILATS R AKR G LQVLR - EL KN KP hrvf L A GA VA eqgfvgdffste VD VN D QTL L V q SNK G TI 781
Cdd:PRK05560 704 QEI L tv T EN G YG KR TPVS E YRLQG R GGK G VITIK i TE KN GK ---- L V GA LP ------------ VD DD D EIM L I - TDS G KL 766
810
....*....|....*..
gi 9230561 782 YES R LQDLNLSE R TSN G 798
Cdd:PRK05560 767 IRT R VSEISITG R NTQ G 783
gyrA
TIGR01063 DNA gyrase, A subunit; This model describes the common type II DNA topoisomerase (DNA gyrase). ...
4-810
0e+00
DNA gyrase, A subunit; This model describes the common type II DNA topoisomerase (DNA gyrase). Two apparently independently arising families, one in the Proteobacteria and one in Gram-positive lineages, are both designated toposisomerase IV. [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 273423 [Multi-domain]
Cd Length: 800
Bit Score: 750.29
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9230561 4 I QNMSL E DI M GERFGR Y SKYI I QD RALPD I RDGLKPV Q RRILY S M NKDSN T F DK S Y R KSA KS VG NI MG NF HPHGDS S IYD 83
Cdd:TIGR01063 1 I VPVNI E EE M KRSYLD Y AMSV I VS RALPD V RDGLKPV H RRILY A M YELGL T P DK P Y K KSA RI VG DV MG KY HPHGDS A IYD 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9230561 84 AM VRM S Q NWKN R EI LV EMH GN N GS M DGDPPAAMRYTEARL SE IA GY LL Q DI E K K TV P F AW N F D DT E K EPTVLP AA FPNLL 163
Cdd:TIGR01063 81 TL VRM A Q DFSL R YP LV DGQ GN F GS I DGDPPAAMRYTEARL TK IA EE LL R DI D K E TV D F VP N Y D GS E Q EPTVLP SR FPNLL 160
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9230561 164 VNGS T GI SA G Y AT D IPPHNL A E V IDA AVYM ID H P TAK I DK L M E FLP GPDFPTG A II Q GR DE I KK AYETG K G RV V V R SKT E 243
Cdd:TIGR01063 161 VNGS S GI AV G M AT N IPPHNL G E I IDA LLAY ID N P DIS I QE L L E VIK GPDFPTG G II L GR SG I RS AYETG R G SI V I R ARA E 240
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9230561 244 IE KLKG G K E Q I VI TEIPY EI NKA N L VK KI DDVRVNN K VA GI AEV RDESDR D G L RI A IELK K DA NT E L VLN Y L F K Y T D LQ I 323
Cdd:TIGR01063 241 IE EDSK G R E A I IV TEIPY QV NKA R L IE KI AELVREK K IE GI SDI RDESDR E G I RI V IELK R DA VA E V VLN N L Y K Q T Q LQ V 320
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9230561 324 NYNF NM V A IDNFT P RQVGIVPI L SSYIA HR RE VI LA R SP F DKE KAE K R LR I V EGL IRVISIL DEVIALIRAS E N KADP K E 403
Cdd:TIGR01063 321 SFGI NM L A LVKGL P KVLNLKEL L EAFVE HR KD VI TR R TI F ELR KAE E R AH I L EGL LIALDNI DEVIALIRAS Q N TEEA K T 400
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9230561 404 N L KVSYDFT E E QA E AI VTLQ L Y RLT NTDVVV LQEE EA EL R E K IA M L AA I IGD E RTMYNLMKK EL R E V K KN F AT PR LSSLE 483
Cdd:TIGR01063 401 R L VERFSLS E I QA Q AI LDMR L Q RLT GLEREK LQEE YK EL L E L IA D L ED I LAS E ERVLEIIRE EL E E I K EQ F GD PR RTEIV 480
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9230561 484 d TAKAIE ID TAS LIA E E DTY V SVTKA GY I KR TSPRSFAASTLEEI G K ----- R DDD RLIFVQS A K T TQH LL M FT SL G N V I 558
Cdd:TIGR01063 481 - YDESED ID IED LIA R E NVV V TLSHN GY V KR VPVSAYRLQKRGGK G V sgadm K DDD FIEQLLV A S T HDY LL F FT NR G K V Y 559
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9230561 559 YRPIHELADIRWKDI G EHLSQTI t NFETN E A I LYVEVLDQ FDD ATTY F A AT RL G QI K RVERK EF T pwr TY RS KSVKYA KL 638
Cdd:TIGR01063 560 WLKVYQIPEASRTAK G KPIVNLL - PLQPD E R I TAILSVKE FDD GLYL F F AT KN G VV K KTSLT EF S --- NI RS NGIIAI KL 635
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9230561 639 K D D t D QIVA V APIKLD D - V V L V S Q NG Y A L RF NI E E V PVV G AK A A GV KAMN LK ED D VLQ S GFICNTS S FY L - L T QR G SL KR 716
Cdd:TIGR01063 636 D D G - D ELIS V RLTSGE D e V M L G S K NG K A V RF PE E D V RPM G RA A R GV RGIK LK NE D FVV S LLVVSEE S YL L i V T EN G YG KR 714
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9230561 717 V SIEE ILA TSR AKR G LQVLRELKNK phrvfla G A V aeqgf VG dff STE VD VN D QTL L V q SNK G TIYESRL QD LNLSE R TS 796
Cdd:TIGR01063 715 T SIEE YRE TSR GGK G VKSIKITDRN ------- G Q V ----- VG --- AIA VD DD D ELM L I - TSA G KLIRTSV QD VSEQG R NT 778
810
....*....|....
gi 9230561 797 N G SFISDTIS D EEV 810
Cdd:TIGR01063 779 Q G VRLIRLDE D DKL 792
TOP4c
cd00187 DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), ...
26-470
0e+00
DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes in DNA topology by catalysing the concerted breakage and rejoining of DNA strands during normal cellular growth.
Pssm-ID: 238111 [Multi-domain]
Cd Length: 445
Bit Score: 644.24
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9230561 26 QD RALPD I RDGLKPVQRRILY S M N K DSN T F DK SYR K S A KS VG NIM G NF HPHGDSS I YD AM VRM S Q NWK N REI L VEMH GN N 105
Cdd:cd00187 1 NG RALPD V RDGLKPVQRRILY A M F K RGL T P DK PEK K V A RL VG DVA G KY HPHGDSS L YD TI VRM A Q DFS N NIP L LDPQ GN F 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9230561 106 GS M DGD PP AAMRYTE A RLS E IA GY LL Q DI EKK TV P F AW N F D DT E K EP T VLP AA FPNLLVNGS T GI SA G Y AT D IPPHNL A E 185
Cdd:cd00187 81 GS R DGD DA AAMRYTE T RLS P IA RL LL P DI DDP TV D F VP N Y D GQ E V EP E VLP PI FPNLLVNGS S GI AV G M AT N IPPHNL R E 160
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9230561 186 VIDA AVYM ID H P T A K ID K LME FLP GPDFPTG A II Q GR DE I KK AYETG K GR VVV R S K T EIE KLK g G KEQ I V ITE I PY EI NK 265
Cdd:cd00187 161 VIDA LRAL ID N P E A S ID E LME IIK GPDFPTG G II E GR AG I RE AYETG R GR YII R G K Y EIE DDE - G RNT I E ITE L PY QV NK 239
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9230561 266 A N L VK KI DDVRVNN K VA GI AE VRDESDR D G L R IA IELK KD A NT E L VLN Y L F K Y T D LQ INYNF NMVA I D - N FT P RQVGIVP 344
Cdd:cd00187 240 A K L KE KI AELVKDK K IE GI SD VRDESDR E G I R FV IELK RG A MA E V VLN G L Y K V T K LQ TTFGI NMVA F D p N GR P KKLNLKE 319
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9230561 345 IL SSYIA HR R EV ILA R SPFDKE KAE K RL R I V EGL IRV I SIL DEVI A LIR A S E nka DP K EN L K --- VSYD F T E E QA E AI VT 421
Cdd:cd00187 320 IL QEFLD HR L EV YTR R KEYELG KAE A RL H I L EGL LKA I LNI DEVI N LIR S S D --- EA K KA L I eel EKLG F S E I QA D AI LD 396
410 420 430 440
....*....|....*....|....*....|....*....|....*....
gi 9230561 422 LQ L Y RLT NTDVVV L QE E EA EL REK I AM L AA I IGD E RTMYN L M K K EL R E V 470
Cdd:cd00187 397 MR L R RLT KLEREK L LK E LK EL EAE I ED L EK I LAS E ERPKD L W K E EL D E F 445
PRK13979
PRK13979 DNA topoisomerase IV subunit A; Provisional
2-672
0e+00
DNA topoisomerase IV subunit A; Provisional
Pssm-ID: 237576 [Multi-domain]
Cd Length: 957
Bit Score: 608.26
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9230561 2 S NI QNMS LE DI M G E RFGR Y SKYIIQ DRALPD I RDGLKPV Q RRILY SMNKDSNTF DK S Y R KSA KS VG N I M G NF HPHGDSS I 81
Cdd:PRK13979 11 N NI IKIP LE EA M P E NYLP Y AVEVAK DRALPD V RDGLKPV H RRILY GAYMLKAFP DK P Y Y KSA RI VG D I L G KY HPHGDSS V 90
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9230561 82 YDAMV RMS Q NWKN R EI L VEM HGN N GS M DGD PP AAMRYTEARL SE IA GYL L Q DI E K KT V PFAW N FD D T EKEP T VLPA AF PN 161
Cdd:PRK13979 91 YDAMV ILA Q DFTT R MP L IDG HGN W GS I DGD SA AAMRYTEARL TP IA MEM L R DI D K DV V NMVD N YS D S EKEP E VLPA RY PN 170
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9230561 162 LLVNG ST GI SA G Y AT D IPPHNL A EVID AAVYM ID HPTAKIDK LM EFLP GPD F PTG A I IQ G RDEIKK AYETG K G R V VV R S K 241
Cdd:PRK13979 171 LLVNG AF GI AV G L AT N IPPHNL K EVID GTLAY ID NNEITTKE LM NYIK GPD L PTG G I LI G KKSLLS AYETG E G K V TL R A K 250
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9230561 242 T E IEKL KG G KEQ IVITE I PY EI NKA N L VKK I DDVRVNN K VA ---- G I AEV RDESDR D G L R IA IE L KK D A NTEL --- VL N Y 314
Cdd:PRK13979 251 T K IEKL EN G RLG IVITE F PY RR NKA K L LQT I SEMTADK K HS kale N I SDI RDESDR N G I R AV IE F KK S A DEDV aek VL K Y 330
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9230561 315 L F K Y TDLQ I N YN FNMVA IDNFT P RQV G IVPI L SS Y IA H RR EV ILA R SPFDK E K AEKR LR IVEG L I RV I S I L DE V I AL IR A 394
Cdd:PRK13979 331 L Y K K TDLQ C N IS FNMVA LADGK P ETM G LKTM L KH Y VE H QK EV VTR R TKKEL E I AEKR FH IVEG F I KA I G I M DE I I KT IR S 410
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9230561 395 S EN K A D PK ENL KVSYD FT E EQAEAI VT L Q LYRLT NTDV V VLQE E EA EL REK I AM L AA I IGD E RTMYNLM KKEL R EVK KNF 474
Cdd:PRK13979 411 S KS K K D AS ENL IEKFG FT D EQAEAI LE L M LYRLT GLEI V AFEK E YK EL EKL I KK L TK I LSS E KELLKVI KKEL K EVK EKY 490
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9230561 475 ATP R LS S L - ED TA KA i E ID TAS LI AE ED TYVSVTKA G Y IKR TSPR S F -- AA S TL E E I GK R DD D RLI F VQSAK T TQH LL M F 551
Cdd:PRK13979 491 GDE R RT S I i ED DE KA - K ID VEE LI VV ED VVITLSNE G F IKR IPLK S Y nr SN S NV E D I EY R EG D FNK F LIQSN T KDT LL I F 569
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9230561 552 T SL GN VIYRPIHELADIR WK DI GE H L SQT I TNFE - TN E A I LYVEVLDQ F DDATTYFAA T RL G Q IK RVERKE F tpw R T YRS 630
Cdd:PRK13979 570 T DK GN MYQIKGINIPEFK WK EK GE R L DEI I KGID l ES E K I IEAYSIED F TPQKDFIFI T DS G G IK KTSLDK F --- V T NYT 646
650 660 670 680
....*....|....*....|....*....|....*....|....*.
gi 9230561 631 K s VKYA KLK DD t DQIVA V APIKLDD ---- VVLVSQN G ya L R F NI EE 672
Cdd:PRK13979 647 K - LMAL KLK KG - EKLIK V KLVDRTR eekf IKIKTKK G -- L S F TV EE 688
DNA_topoisoIV
pfam00521 DNA gyrase/topoisomerase IV, subunit A;
28-468
0e+00
DNA gyrase/topoisomerase IV, subunit A;
Pssm-ID: 459843 [Multi-domain]
Cd Length: 432
Bit Score: 608.01
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9230561 28 RA L PD I RDGLKPVQRRILY S M NK d SNTF DK S Y R K S A KS VG NI MG NF HPHGD S S I YDA M VRM S Q NWKNREI L VEMH GN N GS 107
Cdd:pfam00521 1 RA I PD V RDGLKPVQRRILY A M FE - LLNL DK P Y K K V A RL VG DV MG KY HPHGD A S L YDA I VRM A Q DFVGNIP L LDGQ GN F GS 79
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9230561 108 - M DGD PP AAMRYTE A RLS E IA GY L LQ DI EKK TV PFAW N F D D TE K EPTVLP AAF PNLLVNG ST GI SA G Y AT D IPPHNL A E V 186
Cdd:pfam00521 80 r I DGD KD AAMRYTE T RLS K IA RE L FP DI DDD TV DYVP N Y D G TE V EPTVLP PII PNLLVNG AE GI AV G M AT N IPPHNL R E I 159
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9230561 187 IDA AVYMI D H P T A KI dk LM EFLP GPDFPTG AI I Q G RDE IK K AY E TG K G RVV VR S K T EIE K lkgg KEQ IVITE I PY EINKA 266
Cdd:pfam00521 160 IDA LIALL D G P E A TL -- LM KYIM GPDFPTG GG I I G KGG IK E AY K TG R G KIT VR A K V EIE D ---- RKT IVITE L PY GVWTS 233
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9230561 267 N L VK KI DDVRV N N K VA GI AEV RDESDR d G L RI A IELK KD A NT E L VLN Y L F K Y T D LQ INYNF N MVAIDNFT P RQV G IVP IL 346
Cdd:pfam00521 234 D L IE KI EELVK N G K IK GI SDI RDESDR - G V RI V IELK RG A DP E V VLN D L Y K K T K LQ TSFST N NLVLFDGG P KYL G LKE IL 312
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9230561 347 SSYIA HR R EV ILA R SPFDK EK A E K RL R I V EGL IRVISIL D E VI AL IR A S ENKADP K E NL KV sy DFT E E QA EAIVTLQ L Y R 426
Cdd:pfam00521 313 KEFLD HR L EV YER R KEYLL EK L E E RL H I L EGL LIALNNI D F VI EI IR G S IDRKKA K K NL IE -- ELS E I QA DYLLDMR L R R 390
410 420 430 440
....*....|....*....|....*....|....*....|..
gi 9230561 427 LT NTD V VV L Q EE EA EL REK IA M L AAIIGD E RTMYN L MKK EL R 468
Cdd:pfam00521 391 LT KEE V DK L L EE ID EL EKE IA E L EKLLAS E KKLND L WIE EL D 432
TOP4c
smart00434 DNA Topoisomerase IV; Bacterial DNA topoisomerase IV, GyrA, ParC
7-459
0e+00
DNA Topoisomerase IV; Bacterial DNA topoisomerase IV, GyrA, ParC
Pssm-ID: 214660 [Multi-domain]
Cd Length: 444
Bit Score: 580.29
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9230561 7 MSL ED IMGERFGR YS KYI I QD RA L PD I RDGLKPVQRRILY S M N K DSN T F D KSYR KSA KS VG NI MG NF HPHGDSS I YD AM V 86
Cdd:smart00434 1 IDI ED FINKEYLD YS MSV I NG RA I PD V RDGLKPVQRRILY A M F K RGL T P D EPKV KSA RG VG DV MG KY HPHGDSS L YD TI V 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9230561 87 RM S Q NWK N REI L VEMH GN N GS M - DGD PP AAMRYTE A RLS EI A GY LL Q DI E K K TV P F AW N F D DT E K EPTVLP AAF PNLLVN 165
Cdd:smart00434 81 RM A Q DFS N NYP L LDGQ GN F GS R l DGD DA AAMRYTE T RLS PL A RL LL P DI D K D TV D F VP N Y D GQ E I EPTVLP PII PNLLVN 160
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9230561 166 GS T GI SA G Y AT D IPPHNL A EVIDA AVYM ID H P T A K ID K LM EFLP GPDFPTG AI I Q G RD eikkayetgkg RV VVR S K T EIE 245
Cdd:smart00434 161 GS S GI AV G M AT N IPPHNL R EVIDA VRRL ID N P D A S ID E LM MIPW GPDFPTG GE I V G PG ----------- KY VVR G K I EIE 229
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9230561 246 KLK ggke Q IVITE I PY EI N K A N L VK KI DDVRVNN K VA GI AE VRDES - DR D G L RI A IELK KD A NT E L VLN Y L F K Y T D LQ IN 324
Cdd:smart00434 230 DDN ---- T IVITE L PY QV N T A D L IE KI AELVKDK K IE GI ID VRDES h DR T G V RI V IELK RG A MA E V VLN G L Y K L T K LQ TT 305
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9230561 325 YNF NM V A I - DN FT P RQVGIVP IL SSYIA HR R EV ILA R SPFDKE K A E - K RL R I V EGL IRVI SI L DE V I A LIR A S ENK A - DP 401
Cdd:smart00434 306 FSI NM L A L f DN GR P KKYNLKE IL KEFLD HR L EV YTR R KEYLLG K L E a E RL H I L EGL FIAL SI I DE I I V LIR S S KDL A k EA 385
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|....*...
gi 9230561 402 KE N L KVSYDFT E E QA E AI VTLQ L Y RLT NTD V VV L QE E EA EL REK I AM L AA I IGD E RTM 459
Cdd:smart00434 386 KE K L MERFELS E I QA D AI LDMR L R RLT KLE V EK L EK E LK EL EKE I ED L EK I LAS E EWL 443
parC_Gneg
TIGR01062 DNA topoisomerase IV, A subunit, proteobacterial; Operationally, topoisomerase IV is a type II ...
4-689
1.98e-153
DNA topoisomerase IV, A subunit, proteobacterial; Operationally, topoisomerase IV is a type II topoisomerase required for the decatenation of chromosome segregation. Not every bacterium has both a topo II and a topo IV. The topo IV families of the Gram-positive bacteria and the Gram-negative bacteria appear not to represent a single clade among the type II topoisomerases, and are represented by separate models for this reason. [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 130134 [Multi-domain]
Cd Length: 735
Bit Score: 466.31
E-value: 1.98e-153
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9230561 4 I Q N MS L EDIMG E RFGR YS K Y I I Q DRALP D I R DGLKPVQRRI L Y S M NKDSNTFDKS Y R KSA KS VG NIM G NF HPHGDS SI Y D 83
Cdd:TIGR01062 1 I E N ID L GNFTE E AYLN YS M Y V I M DRALP F I G DGLKPVQRRI V Y A M SELGLNANAK Y K KSA RT VG DVL G KY HPHGDS AC Y E 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9230561 84 AMV R M S Q NWKN R EI LV EMH GN N G SM D G - DPP AAMRYTE A RLS E I AGY LL QDIEKK TV P F AW NFD D T EK EP TV LPA AF PN L 162
Cdd:TIGR01062 81 AMV L M A Q PFSY R YP LV DGQ GN W G AP D D p KSF AAMRYTE S RLS K I SEL LL EELGQG TV D F RP NFD G T LL EP VI LPA RL PN I 160
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9230561 163 L V NG S TGI SA G Y ATDIPPHNL A E VI DAA V Y M ID H P T A KI D KLMEFLP GPDFPT G A - II QGRD EI K K A YETG K G RVVV R SK 241
Cdd:TIGR01062 161 L L NG T TGI AV G M ATDIPPHNL H E LA DAA L Y L ID N P K A GL D DILNIVQ GPDFPT E A e II DKAE EI R K I YETG R G SFRM R AR 240
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9230561 242 TEI E KL kggke QIVI TEI P YE I N K ANLVKK I DDVRVNN K VAG I AEV RDESD R - DGL R IA I ELKKDA - NTEL V LNY LF KY T 319
Cdd:TIGR01062 241 WKK E DG ----- QIVI SAL P HQ I S K SKVIEQ I AIQMKDK K LPM I SDI RDESD H e NPI R VV I VPRSNR v DPDI V MEH LF AT T 315
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9230561 320 DL QIN Y -- N F NM VAI DN f T P RQVGIVP IL SSYIAH RR EVILA R SPFDKE K AEK RL R I V EGL IRVISIL DEVI AL IR ase N 397
Cdd:TIGR01062 316 DL EKS Y rl N M NM IGL DN - V P AVKNLLE IL QEWLVF RR NTVIR R LTYRLN K VLQ RL H I L EGL RIAFLNI DEVI EI IR --- E 391
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9230561 398 KAD PK EN L KVSYDFTEE QAEAI VT L Q L YR L TNTDVVVLQE E EA EL REKI A M L AA I IGD ER TMYN L M KKE LREVKKNFATP 477
Cdd:TIGR01062 392 EDE PK TI L MERFKLSAI QAEAI LN L R L RH L AKLEEHAIID E QS EL EKER A I L EK I LKS ER ELNQ L V KKE IQADATKYGLA 471
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9230561 478 R L SSLE DTAK A IEIDTASL I AE E DTYVSVT K A G YIKRTSPRSFAA STL E eig KRDD D RLIFVQSA K TT Q HLLMFT S L G N v 557
Cdd:TIGR01062 472 R R SSLE EREE A KQVSEIDM I PK E PVTIILS K M G WVRSAKGHDIDL STL K --- YKAG D SEKAIIEG K SN Q KVVFID S T G R - 547
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9230561 558 i YRPIHELADIRWKDI GE H L SQTI t NFETNEA I LYV ------ EV L DQFD DA TTY F AATRLGQ I K R VERKEFTPWRTYRSK 631
Cdd:TIGR01062 548 - SYALDPDNLPSARGQ GE P L TGKL - LLPIGAT I TNI lmyspn QL L LMAS DA GYG F LCNFNDL I A R NKAGKALINLPENAS 625
650 660 670 680 690
....*....|....*....|....*....|....*....|....*....|....*...
gi 9230561 632 SVKYAKLKD D T D Q I V A vapiklddvvl VSQN G YA L R F N I EEV P VV g A K AA G V K AMNLK 689
Cdd:TIGR01062 626 VIAPLPVNG D S D M I A A ----------- ITEA G RM L V F P I DDL P EL - S K GK G N K LIRIP 671
PRK09631
PRK09631 DNA topoisomerase IV subunit A; Provisional
7-447
1.99e-57
DNA topoisomerase IV subunit A; Provisional
Pssm-ID: 236598 [Multi-domain]
Cd Length: 635
Bit Score: 208.02
E-value: 1.99e-57
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9230561 7 M SLEDIMGER F GR Y SK Y I I Q DRA L PD IR DGLKPVQRRIL Y S M nkd SNTF D KSYR K S A KS VGN I M g NF HPHGD S SIY D A M V 86
Cdd:PRK09631 2 M DIKTLFKDN F LQ Y AS Y V I K DRA I PD VI DGLKPVQRRIL H S L --- FEMH D GKFH K V A NV VGN T M - KY HPHGD A SIY E A L V 77
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9230561 87 RMS qnwk N REILVEMH GN N G SM - D GDP PA A M RY T E A RL SEI A GYL L qd IE K KTVPFAWNF D DTEK EP TV LPA AF P NL L VN 165
Cdd:PRK09631 78 NLA ---- N KDLFIDKQ GN F G NL f T GDP AS A A RY I E C RL TPL A KEV L -- YN K EITEYEPSY D GRNN EP LC LPA KI P VI L IQ 151
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9230561 166 G ST GI SA G Y AT D I P PHN LA E VID A AV ymidhpta KIDKLME F LPG PDFPTG A I IQGRD eikka Y ET G K G R V V VR S K T E IE 245
Cdd:PRK09631 152 G AE GI AV G M AT K I L PHN FN E ILQ A VK -------- SELLGES F ALY PDFPTG G I VDVSE ----- Y AD G N G K V L VR A K I E TK 218
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9230561 246 KL K ggke Q IVI T EIP YEINKAN L VKK I DDVRVNN K VA g I AEVR D ES d RDGLR I A I E L KKDANTEL V LNY L FK YTD LQINY 325
Cdd:PRK09631 219 DE K ---- T IVI R EIP FGTTTES L IAS I EKAARKG K IK - I SSIN D YT - AENVE I E I K L PRGVYASE V IEA L YA YTD CEVSI 292
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9230561 326 NF N MVA I DNFT P RQVGIVP I LSSYIA H RRE V ILARSPFDKE K AEKRL -- RIV E GL --------- I RV IS ILDE VI ALI r A 394
Cdd:PRK09631 293 SV N LLV I KDRY P VIYTVTD I IKFHAE H LQK V LKMELELERA K LLEKI fa KTL E QI fieeriykr I ET IS SEED VI SIV - L 371
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|...
gi 9230561 395 SE N K ADPK E nlk V S Y D F TEE QA E AIVTLQLY R LTNT D VVVL Q E E EAE L REKIA 447
Cdd:PRK09631 372 SE L K PFKE E --- L S R D V TEE DI E NLLKIPIR R ISLF D IDKN Q K E IRI L NKELK 421
PRK12758
PRK12758 DNA gyrase/topoisomerase IV subunit A;
20-346
1.82e-51
DNA gyrase/topoisomerase IV subunit A;
Pssm-ID: 237192 [Multi-domain]
Cd Length: 869
Bit Score: 194.07
E-value: 1.82e-51
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9230561 20 Y SK Y I I QD RA L P D I R DGLKPVQRRIL Y SM NKDS ntf D KS Y R K S A KS VG NI M g NF HPHGD S SI Y DA M V RMS Q nwkn REI L V 99
Cdd:PRK12758 34 Y AS Y V I LE RA V P H I E DGLKPVQRRIL H SM KEMD --- D GR Y N K V A NV VG HT M - QY HPHGD A SI G DA L V QLG Q ---- KDL L I 105
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9230561 100 EMH GN N G S - MD GD PP AA M RY T EARLS EI A gyll QDI -- EK KT VPFAWNF D DTE KEP TV LP AA FP N LL VN G ST GI SA G YA T 176
Cdd:PRK12758 106 DTQ GN W G N i LT GD GA AA P RY I EARLS KF A ---- LEV vf NP KT TEWQLSY D GRK KEP VT LP VK FP L LL AQ G AE GI AV G LS T 181
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9230561 177 D I P PHN LA E V IDA AV ymidhpta KID K LM EF LPG PDFPTG A II Q grdei KKA Y ET G K -- GRV V VR S K te IEKL K gg K EQI 254
Cdd:PRK12758 182 K I L PHN FN E L IDA SI -------- AYL K GK EF KLY PDFPTG G II D ----- VSN Y ND G E rg GRV R VR A K -- IEKL D -- K KTL 244
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9230561 255 VITEIPY EINKAN L VKK I dd VRV N N K va G --- I AE V R D ESDR D g LR I AIE L KKDANTELVLNY L FKY TD LQINYNF N MVA 331
Cdd:PRK12758 245 VITEIPY GTTTSS L IDS I -- LKA N D K -- G kik I KK V E D NTAA D - VE I LVH L APGVSPDKTIDA L YAF TD CEVSISP N ACV 319
330
....*....|....*
gi 9230561 332 I DNFT P RQV G IVP IL 346
Cdd:PRK12758 320 I IDNK P HFL G VSD IL 334
PRK09630
PRK09630 DNA topoisomerase IV subunit A; Provisional
9-346
5.16e-45
DNA topoisomerase IV subunit A; Provisional
Pssm-ID: 170022
Cd Length: 479
Bit Score: 168.92
E-value: 5.16e-45
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9230561 9 LE D IMGER F GR Y SK Y I I QD RA L P D I R DGLKPVQRR I L YSMNKDS ntf D KSYR K S A KSV G NI M G n F HPHGD SS I YD A M V RM 88
Cdd:PRK09630 4 VS D LFKTH F MH Y AS Y V I LE RA I P H I L DGLKPVQRR L L WTLFRMD --- D GKMH K V A NIA G RT M A - L HPHGD AP I VE A L V VL 79
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9230561 89 S qnwk N REI L VEMH GN N G S - MD GDP P AA M RY T EARLS EI A GYL L QDIEKK T vp F AWNF D DT EKEP TV LPA AF P N LL VN G S 167
Cdd:PRK09630 80 A ---- N KGY L IDTQ GN F G N p LT GDP H AA A RY I EARLS PL A KEV L FNTDLM T -- F HDSY D GR EKEP DI LPA KL P L LL LH G V 153
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9230561 168 T GI SA G YA T D I P PHN LA E VID A AVYMID hptaki D KLMEF L pg PDFP T G AIIQGRD eikka Y ET G K G RVVV R SKTE I EKL 247
Cdd:PRK09630 154 D GI AV G MT T K I F PHN FC E LLE A QIAILN ------ D QPFTL L -- PDFP S G GTMDASE ----- Y QD G L G SITL R ASID I IND 220
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9230561 248 K ggke QIV I T EI PYEINKAN L VKK I DDV r VNNKVAG I AEVR D E S D r D GLR I A I E L K K DANTELV L NY LF KY T DL Q INYNF 327
Cdd:PRK09630 221 K ---- TLL I K EI CPSTTTET L IRS I ENA - AKRGIIK I DSIQ D F S T - D LPH I E I K L P K GIYAKDL L RP LF TH T EC Q VILTS 294
330
....*....|....*....
gi 9230561 328 NMV AI DNFT P RQVG I VP IL 346
Cdd:PRK09630 295 RPT AI YQNK P VETS I SE IL 313
52
PHA02592 DNA topisomerase II medium subunit; Provisional
3-472
3.68e-38
DNA topisomerase II medium subunit; Provisional
Pssm-ID: 222896 [Multi-domain]
Cd Length: 439
Bit Score: 148.28
E-value: 3.68e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9230561 3 NIQNM SL ED I MGERFGR Y SK Y IIQD RA L P DIR DGLKPVQR RILYS ---- MNKDSNT FDK syrksaks V GN I M G ----- NF 73
Cdd:PHA02592 2 QLKER SL KS I VNNEALE Y AM Y TVEE RA I P NLI DGLKPVQR FVIHR aley AKGNKEK FDK -------- V AA I A G gvadl GY 73
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9230561 74 H p HG DS S IY DA MVR M SQN W K N REI L VEMH GN N GS MDGDPP AA M RY TE AR LSE iagy LLQD I E K KT vpfaw NFDDTEKE P T 153
Cdd:PHA02592 74 H - HG ET S AQ DA GAL M ANT W N N NIP L LDGQ GN F GS RLVQKA AA A RY IF AR VHD ---- NFRK I Y K DE ----- DLAPVHED P E 143
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9230561 154 VL P A AF ----- P NL L V NG ST GI SA GYAT D I P PH NLAE VI D A AVYMID hp TAK I DK lmefl P GPD FP tgaii QGRD E IK ka 228
Cdd:PHA02592 144 HI P P AF ylpii P MV L L NG VS GI AT GYAT N I L PH SPKS VI K A VLAALN -- GKD I TE ----- P KVQ FP ----- EFKG E VV -- 209
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9230561 229 y E TGK G RVVV R SKT E IE klkg GK EQIV ITEIP YEINKANL V KKI D DVRVNN K VAGI aevr D ESDR DG L R IAIE LK KDA N T 308
Cdd:PHA02592 210 - E IEP G SYEI R GTY E LN ---- GK TKLH ITEIP VKYDRETY V AVL D PLEEKG K IVSY ---- D DCTE DG F R FKVT LK REE N E 280
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9230561 309 E LVLNYLF K YTD L QINYNF N MVA I DNFTPRQ V -- GIVPILSSYIAH R REVILA R SPFDKEKA E KRLRIV eg L IRVIS I l D 386
Cdd:PHA02592 281 E ATHEKIM K DFG L IERVSQ N ITV I NENGKLK V ye NAEDLIRDFVEI R KTYVQK R IQYEIKET E EAFDLA -- L AKAEF I - K 357
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9230561 387 E VIA LIRASEN K ADPKENLKV S - YDFTE E Q A EAI V TLQL Y RL T NTDVVV LQ E E EA EL REKIAMLAAI ig DERTM Y nlm K K 465
Cdd:PHA02592 358 R VIA GEIVLQG K TRSELTEEL S d NKDFG E Y A DKL V AMNI Y SM T SDEREK LQ K E AE EL EKEHEYWKKT -- TAKKE Y --- I K 432
....*..
gi 9230561 466 E L R E V KK 472
Cdd:PHA02592 433 D L E E L KK 439
PTZ00108
PTZ00108 DNA topoisomerase 2-like protein; Provisional
28-642
1.53e-18
DNA topoisomerase 2-like protein; Provisional
Pssm-ID: 240271 [Multi-domain]
Cd Length: 1388
Bit Score: 91.26
E-value: 1.53e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9230561 28 R AL P DIR DGLKP V QR R IL YSM nkdsnt F DKSYRKSA K s V GNIM G ------ NF H p HG DS S IYDAM V R M S QN W -- K N REI L V 99
Cdd:PTZ00108 680 R SI P SLV DGLKP G QR K IL FAC ------ F KRNLKNEI K - V AQLS G yvsehs AY H - HG EQ S LQQTI V G M A QN F vg S N NIN L L 751
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9230561 100 EMH G NN GS -- MD G DPP AA M RY TEAR LS E I AG Y -------- L L QDI E kktvpfawnf DD TEK - EP TVLPAAF P NL LVNG ST 168
Cdd:PTZ00108 752 YPC G QF GS rl QG G KDH AA A RY IFTK LS K I TR Y ifpeeddp I L DYL E ---------- DD GQS v EP FYYVPII P MV LVNG AE 821
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9230561 169 GI SA G YA T D IP PH N LAEV ID AAVYMIDH ptaki DKLMEFL P gpd FPT G ai IQ G RD E IK kayet G KG R vv VR SK TEI EK LK 248
Cdd:PTZ00108 822 GI GT G FS T S IP NY N PLDI ID NLRRRLNG ----- EEVRPLV P --- WYR G -- FK G TI E RN ----- P KG K -- FI SK GIY EK VP 884
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9230561 249 G G ke QIV ITE I P YEINKANLVKKIDDVRVNN K VA g I AEV RD E S DRDGLRIAIE L KKDANTELVLNYLF K YTD L Q -- I NYN 326
Cdd:PTZ00108 885 D G -- TVE ITE L P IGKWTEDYKEFLESETLKE K DV - I VDY RD Y S TANTVHFTVK L NDGVLEQWEEEGIE K VFK L K st I STT 961
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9230561 327 f NMV AI D -- NFTPRQVGIVP IL SSYIAH R REVILA R SPFDKE K A E KR L RIVEGLI R V I S - ILDEVIALIR A S en K A D PKE 403
Cdd:PTZ00108 962 - NMV LF D en GKIKKYSDALD IL KEFYLV R LDLYKK R KEYLLG K L E RE L ARLSNKV R F I K h VINGELVITN A K -- K K D LVK 1038
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9230561 404 N LK ---- V SYDFTEEQAEAIV T LQLYRLTNT D VVVLQ E EEA E L ------------------- R EK IAM L aaiigde RTMY 460
Cdd:PTZ00108 1039 E LK klgy V RFKDIIKKKSEKI T AEEEEGAEE D DEADD E DDE E E lgaavsydyllsmpiwslt K EK VEK L ------- NAEL 1111
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9230561 461 NLMK KEL REV K K nf A TP RLSS LED TA K AI E I dtasl IA E EDTYVSVTK A GYIKRT S PRSFA AS T L EEIGKRDDDRLIFVQ 540
Cdd:PTZ00108 1112 EKKE KEL EKL K N -- T TP KDMW LED LD K FE E A ----- LE E QEEVEEKEI A KEQRLK S KTKGK AS K L RKPKLKKKEKKKKKS 1184
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9230561 541 SA KTTQHLLMFTSLGN V IYRPIHE L A D IRWKDIGEHLSQTITN ---- FETNEAILYVEVLDQFDDATTYFAATRLGQIKR 616
Cdd:PTZ00108 1185 SA DKSKKASVVGNSKR V DSDEKRK L D D KPDNKKSNSSGSDQED deeq KTKPKKSSVKRLKSKKNNSSKSSEDNDEFSSDD 1264
650 660
....*....|....*....|....*.
gi 9230561 617 VERKEFTPWRTY R SKS V K Y AKLKDDT 642
Cdd:PTZ00108 1265 LSKEGKPKNAPK R VSA V Q Y SPPPPSK 1290
PLN03128
PLN03128 DNA topoisomerase 2; Provisional
6-449
2.48e-17
DNA topoisomerase 2; Provisional
Pssm-ID: 215593 [Multi-domain]
Cd Length: 1135
Bit Score: 87.07
E-value: 2.48e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9230561 6 NM S LE D IMGERFGRY S KYII q D R AL P DIR DGLKP V QR RI L YS mnkdsn T F DKSYRKSA K s V GNIM G ----- NFHP HG DS S 80
Cdd:PLN03128 652 GI S YS D FINKELILF S QADL - A R SI P SMV DGLKP S QR KV L FA ------ C F KRNLKSEI K - V AQLS G yvaeh SAYH HG EA S 723
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9230561 81 IYDAMVR M S Q NW --- K N REI L VEM h G NN G S -- MD G DPP A AM RY TEA RLS E I AGY L LQ di EKKT V PFAWNFD D TEK - EP TV 154
Cdd:PLN03128 724 LASTIIG M A Q DF vgs N N INL L TPS - G QF G T rl QG G KDA A SA RY IFT RLS P I TRA L FP -- KDDD V LLNYLNE D GQS i EP EW 800
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9230561 155 LPAAF P NL LVNGS T GI SA G YA T D IP PH N LAEV I daavymidhpt A K I DK L ME flp G PDFP --------- T G A I IQGRDEI 225
Cdd:PLN03128 801 YCPII P MV LVNGS E GI GT G WS T F IP NY N PRDI I ----------- A N I RR L LR --- G EELE pmhpwyrgf K G T I TEVSTSR 866
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9230561 226 KKA Y ET g K G RVVVRSK T E I E klkggkeqiv ITE I P ------- Y ein K AN L VKKIDDVR vn N K VAG I AEVRDESDRDGLRI 298
Cdd:PLN03128 867 SGS Y TV - T G IIEQIGD T T I R ---------- ITE L P vrkwtqd Y --- K EF L EALLTGTK -- K K EPE I KDFKENHTDTTVHF 930
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9230561 299 AIE L KKDANTELV --- L NYL FK Y - T DLQIN ynf NM VAI D NF ------- T P RQVGI -- VPILSSYIAH R R EV I L ARSPFDK 365
Cdd:PLN03128 931 TVT L SEEKMARAL aeg L EKK FK L s T TISTS --- NM HLF D KD gkikkyd S P EDILE ef FHLRLDLYVK R K EV L L ENLEYEL 1007
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9230561 366 E K AEKRL R IVEGLIRVISILD ----- E VI A LIRASENKAD PK ENLKVS ------- YDFTE E QA EA I ----------- VTL 422
Cdd:PLN03128 1008 K K LDNKA R FILAVVKGEIVVN nrkra E LL A ELEEKGFDKF PK TAKISE tnvvgdr DGEAS E EE EA S dnelaksydyl LGM 1087
490 500
....*....|....*....|....*..
gi 9230561 423 QLYR LT NTD V VV L QE E E A ELREKIAM L 449
Cdd:PLN03128 1088 PISS LT LEK V DE L RA E R A KKETEVEE L 1114
DNA_gyraseA_C
pfam03989 DNA gyrase C-terminal domain, beta-propeller; This repeat is found as 6 tandem copies at the ...
654-701
3.15e-11
DNA gyrase C-terminal domain, beta-propeller; This repeat is found as 6 tandem copies at the C-termini of GyrA and ParC DNA gyrases. It is predicted to form 4 beta strands and to probably form a beta-propeller structure. This region has been shown to bind DNA non-specifically and may stabilize the DNA-topoisomerase complex.
Pssm-ID: 427633 [Multi-domain]
Cd Length: 48
Bit Score: 58.65
E-value: 3.15e-11
10 20 30 40
....*....|....*....|....*....|....*....|....*...
gi 9230561 654 D DVV L VSQN GY AL R FNIE E VPVV G AK A A GVK AM NLKE D D VLQ S GFIC N 701
Cdd:pfam03989 1 D ELL L ITSK GY VK R TPLS E IREQ G RG A K GVK GI NLKE G D KVV S VLVV N 48
PLN03237
PLN03237 DNA topoisomerase 2; Provisional
28-188
6.46e-11
DNA topoisomerase 2; Provisional
Pssm-ID: 215641 [Multi-domain]
Cd Length: 1465
Bit Score: 66.42
E-value: 6.46e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9230561 28 R AL P DIR DGLKP V QR R IL YS mnkdsn T F DKSYR K S AK s V GNIM G ------ NF H p HG DS S IYDAMVR M S Q NW -- K N REI L V 99
Cdd:PLN03237 698 R SI P SMV DGLKP G QR K IL FC ------ S F KRNFV K E AK - V AQLS G yvsehs AY H - HG EQ S LASTIIG M A Q DF vg S N NIN L L 769
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9230561 100 EMH G NN G -- SMD G DPP A AM RY TEA RLS E I AGY L LQDIEKKTVPFA w N F D DTEK EPT VLPAAF P NL LVNG ST GI SA G YA T D 177
Cdd:PLN03237 770 LPN G QF G tr LQG G KDH A SA RY IFT RLS P I TRF L FPKDDDILLDYL - N E D GQSI EPT WYMPII P TV LVNG AE GI GT G WS T F 848
170
....*....|.
gi 9230561 178 IP PH N LAEVID 188
Cdd:PLN03237 849 IP NY N PRDIVA 859
Blast search parameters
Data Source:
Precalculated data, version = cdd.v.3.21
Preset Options: Database: CDSEARCH/cdd Low complexity filter: no Composition Based Adjustment: yes E-value threshold: 0.01
