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Conserved domains on  [gi|919034376|ref|XP_013400796|]
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ubiquinone biosynthesis monooxygenase COQ6, mitochondrial [Lingula anatina]

Protein Classification

Rossmann-fold NAD(P)-binding domain-containing protein( domain architecture ID 229380)

Rossmann-fold NAD(P)-binding domain-containing protein may function as an oxidoreductase

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
NADB_Rossmann super family cl21454
Rossmann-fold NAD(P)(+)-binding proteins; A large family of proteins that share a ...
 45-473 0e+00

Rossmann-fold NAD(P)(+)-binding proteins; A large family of proteins that share a Rossmann-fold NAD(P)H/NAD(P)(+) binding (NADB) domain. The NADB domain is found in numerous dehydrogenases of metabolic pathways such as glycolysis, and many other redox enzymes. NAD binding involves numerous hydrogen-bonds and van der Waals contacts, in particular H-bonding of residues in a turn between the first strand and the subsequent helix of the Rossmann-fold topology. Characteristically, this turn exhibits a consensus binding pattern similar to GXGXXG, in which the first 2 glycines participate in NAD(P)-binding, and the third facilitates close packing of the helix to the beta-strand. Typically, proteins in this family contain a second domain in addition to the NADB domain, which is responsible for specifically binding a substrate and catalyzing a particular enzymatic reaction.


The actual alignment was detected with superfamily member TIGR01989:

Pssm-ID: 473865 [Multi-domain]  Cd Length: 437  Bit Score: 526.63  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 919034376   45 FDVVISGGGMVGAAMACALGHANVFEDKKILLLEASPQKD------FKLPEKYGNRVCALSPATKKLLSGFGAWEEICNM 118
Cdd:TIGR01989   1 FDVVIVGGGPVGLALAAALGNNPLTKDLKVLLLDAVDNPKlksrnyEKPDGPYSNRVSSITPASISFFKKIGAWDHIQSD 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 919034376  119 RYQPVKRMQVWDACSDAFITLNHDDMTDDVAYIVENDVILAAIMKQF-DKIKHNVTVMYNSKAEMYTFPSQIQDgvqENL 197
Cdd:TIGR01989  81 RIQPFGRMQVWDGCSLALIRFDRDNGKEDMACIIENDNIQNSLYNRLqEYNGDNVKILNPARLISVTIPSKYPN---DNS 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 919034376  198 -WIKVHLPDGETFQTKLLIGADGFNSLVRKQANIHTLQWDYEQWGLVSTLHFAEPTENVVAWQRFLPTGPVAVLPLSETQ 276
Cdd:TIGR01989 158 nWVHITLSDGQVLYTKLLIGADGSNSNVRKAANIDTTGWNYNQHAVVATLKLEEATENDVAWQRFLPTGPIALLPLPDNN 237

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 919034376  277 SSLVWTTSPDEAKRLLKLPKENFVDALNMALWDEDKKDS---FAVRAGQVAQDLINTVSPEGTSFRQLPPTFTDIEDESR 353
Cdd:TIGR01989 238 STLVWSTSPEEALRLLSLPPEDFVDALNAAFDLGYSDHPysyLLDYAMEKLNEDIGFRTEGSKSCFQVPPRVIGVVDKSR 317

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 919034376  354 AAFPLSLVHASHYVKPRLALIGDAAHRVHPLAGQGVNLGFGDVTCLRDVLVQCLCNGGDLGSLSHLLQYETSRQRKVLPV 433
Cdd:TIGR01989 318 AAFPLGLGHADEYVTKRVALVGDAAHRVHPLAGQGVNLGFGDVASLVKALAEAVSVGADIGSISSLKPYERERYAKNVVL 397

                         410       420       430       440
                  ....*....|....*....|....*....|....*....|
gi 919034376  434 MFAMDGLKRLYGTDFPPVVVLRTLGLQATNSMKSLKDFFV 473
Cdd:TIGR01989 398 LGLVDKLHKLYATDFPPVVALRTFGLNLTNYIGPLKNFIM 437
 
Name Accession Description Interval E-value
COQ6 TIGR01989
ubiquinone biosynthesis monooxygenase COQ6; This model represents the monooxygenase ...
 45-473 0e+00

ubiquinone biosynthesis monooxygenase COQ6; This model represents the monooxygenase responsible for the 4-hydroxylateion of the phenol ring in the aerobic biosynthesis of ubiquinone


Pssm-ID: 273914 [Multi-domain]  Cd Length: 437  Bit Score: 526.63  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 919034376   45 FDVVISGGGMVGAAMACALGHANVFEDKKILLLEASPQKD------FKLPEKYGNRVCALSPATKKLLSGFGAWEEICNM 118
Cdd:TIGR01989   1 FDVVIVGGGPVGLALAAALGNNPLTKDLKVLLLDAVDNPKlksrnyEKPDGPYSNRVSSITPASISFFKKIGAWDHIQSD 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 919034376  119 RYQPVKRMQVWDACSDAFITLNHDDMTDDVAYIVENDVILAAIMKQF-DKIKHNVTVMYNSKAEMYTFPSQIQDgvqENL 197
Cdd:TIGR01989  81 RIQPFGRMQVWDGCSLALIRFDRDNGKEDMACIIENDNIQNSLYNRLqEYNGDNVKILNPARLISVTIPSKYPN---DNS 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 919034376  198 -WIKVHLPDGETFQTKLLIGADGFNSLVRKQANIHTLQWDYEQWGLVSTLHFAEPTENVVAWQRFLPTGPVAVLPLSETQ 276
Cdd:TIGR01989 158 nWVHITLSDGQVLYTKLLIGADGSNSNVRKAANIDTTGWNYNQHAVVATLKLEEATENDVAWQRFLPTGPIALLPLPDNN 237

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 919034376  277 SSLVWTTSPDEAKRLLKLPKENFVDALNMALWDEDKKDS---FAVRAGQVAQDLINTVSPEGTSFRQLPPTFTDIEDESR 353
Cdd:TIGR01989 238 STLVWSTSPEEALRLLSLPPEDFVDALNAAFDLGYSDHPysyLLDYAMEKLNEDIGFRTEGSKSCFQVPPRVIGVVDKSR 317

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 919034376  354 AAFPLSLVHASHYVKPRLALIGDAAHRVHPLAGQGVNLGFGDVTCLRDVLVQCLCNGGDLGSLSHLLQYETSRQRKVLPV 433
Cdd:TIGR01989 318 AAFPLGLGHADEYVTKRVALVGDAAHRVHPLAGQGVNLGFGDVASLVKALAEAVSVGADIGSISSLKPYERERYAKNVVL 397

                         410       420       430       440
                  ....*....|....*....|....*....|....*....|
gi 919034376  434 MFAMDGLKRLYGTDFPPVVVLRTLGLQATNSMKSLKDFFV 473
Cdd:TIGR01989 398 LGLVDKLHKLYATDFPPVVALRTFGLNLTNYIGPLKNFIM 437
PRK07608 PRK07608
UbiH/UbiF family hydroxylase;
41-478 1.10e-84

UbiH/UbiF family hydroxylase;


Pssm-ID: 181057 [Multi-domain]  Cd Length: 388  Bit Score: 265.66  E-value: 1.10e-84
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 919034376  41 NSQLFDVVISGGGMVGAAMACALGHAnvfeDKKILLLEASPQKDfKLPEKYGNRVCALSPATKKLLSGFGAWEEICNMRY 120
Cdd:PRK07608   2 YHMKFDVVVVGGGLVGASLALALAQS----GLRVALLAPRAPPR-PADDAWDSRVYAISPSSQAFLERLGVWQALDAARL 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 919034376 121 QPVKRMQVW-DAcsDAFITLNHDDM-TDDVAYIVENDVILAAIMKQFdKIKHNVTVmYNSKAEMYTFPsqiQDGVQenlw 198
Cdd:PRK07608  77 APVYDMRVFgDA--HARLHFSAYQAgVPQLAWIVESSLIERALWAAL-RFQPNLTW-FPARAQGLEVD---PDAAT---- 145

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 919034376 199 ikVHLPDGETFQTKLLIGADGFNSLVRKQANIHTLQWDYEQWGLVStlHF-AEPTENVVAWQRFLPTGPVAVLPLSETQS 277
Cdd:PRK07608 146 --LTLADGQVLRADLVVGADGAHSWVRSQAGIKAERRPYRQTGVVA--NFkAERPHRGTAYQWFRDDGILALLPLPDGHV 221

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 919034376 278 SLVWTTSPDEAKRLLKLPKENFVDALnmalwdedkkdsfaVRAGQVAQDLINTVSPegtsfrqlpptftdiedesRAAFP 357
Cdd:PRK07608 222 SMVWSARTAHADELLALSPEALAARV--------------ERASGGRLGRLECVTP-------------------AAGFP 268

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 919034376 358 LSLVHASHYVKPRLALIGDAAHRVHPLAGQGVNLGFGDVTCLRDVLVQcLCNGGDLGSLSHLLQYETSRQRKVLPVMFAM 437
Cdd:PRK07608 269 LRLQRVDRLVAPRVALVGDAAHLIHPLAGQGMNLGLRDVAALADVLAG-REPFRDLGDLRLLRRYERARREDILALQVAT 347

                        410       420       430       440
                 ....*....|....*....|....*....|....*....|.
gi 919034376 438 DGLKRLYGTDFPPVVVLRTLGLQATNSMKSLKDFFVTQATN 478
Cdd:PRK07608 348 DGLQRLFALPGPLARWLRNAGMALVGALPLVKRWLVRHALG 388
UbiH COG0654
2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases [Coenzyme ...
 45-469 1.76e-60

2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases [Coenzyme transport and metabolism, Energy production and conversion]; 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases is part of the Pathway/BioSystem: Ubiquinone biosynthesis


Pssm-ID: 440419 [Multi-domain]  Cd Length: 326  Bit Score: 200.93  E-value: 1.76e-60
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 919034376  45 FDVVISGGGMVGAAMACALGHANVfedkKILLLEASPqkdfklPEKYGNRVCALSPATKKLLSGFGAWEEICnMRYQPVK 124
Cdd:COG0654    4 TDVLIVGGGPAGLALALALARAGI----RVTVVERAP------PPRPDGRGIALSPRSLELLRRLGLWDRLL-ARGAPIR 72

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 919034376 125 RMQVWDACSDAFIT-LNHDDMTDDVAYIVENDVILAAIMKQFDKikHNVTVMYNSKAEMYTfpsQIQDGVQenlwikVHL 203
Cdd:COG0654   73 GIRVRDGSDGRVLArFDAAETGLPAGLVVPRADLERALLEAARA--LGVELRFGTEVTGLE---QDADGVT------VTL 141

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 919034376 204 PDGETFQTKLLIGADGFNSLVRKQANIHTLQWDYEQWGLVSTLHfaeptenvvawqrflptgpvavlplsetqsslvwtt 283
Cdd:COG0654  142 ADGRTLRADLVVGADGARSAVRRLLGIGFTGRDYPQRALWAGVR------------------------------------ 185

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 919034376 284 spdeakrllklpkenfvdalnMALWDEdkkdsfavragqvaqdlintvspegtsFRQLPPTFTDIED-ESRAAFPLSLVH 362
Cdd:COG0654  186 ---------------------TELRAR---------------------------LAAAGPRLGELLElSPRSAFPLRRRR 217

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 919034376 363 ASHYVKPRLALIGDAAHRVHPLAGQGVNLGFGDVTCLRDVLVQCLcNGGDLGSLshLLQYETSRQRKVLPVMFAMDGLKR 442
Cdd:COG0654  218 AERWRRGRVVLLGDAAHTMHPLGGQGANLALRDAAALAWKLAAAL-RGRDDEAA--LARYERERRPRAARVQRAADALGR 294

                        410       420
                 ....*....|....*....|....*..
gi 919034376 443 LYGTDFPPVVVLRTLGLQATNSMKSLK 469
Cdd:COG0654  295 LFHPDSPPLRLLRNAGLRLLDRLPPLK 321
FAD_binding_3 pfam01494
FAD binding domain; This domain is involved in FAD binding in a number of enzymes.
 46-399 3.57e-14

FAD binding domain; This domain is involved in FAD binding in a number of enzymes.


Pssm-ID: 396193 [Multi-domain]  Cd Length: 348  Bit Score: 73.51  E-value: 3.57e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 919034376   46 DVVISGGGMVGAAMACALGHANVfedkKILLLEaspqkdfKLPEKYGN-RVCALSPATKKLLSGFGAWEEICNMRYqPVK 124
Cdd:pfam01494   3 DVLIVGGGPAGLMLALLLARAGV----RVVLVE-------RHATTSVLpRAHGLNQRTMELLRQAGLEDRILAEGV-PHE 70

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 919034376  125 RMQVWDACSDAFITLNHDDMTDDVAYI----VENDVILAAIMKQFDkIKHNvtvmynskAEMYTFPsQIQDGVQENlwIK 200
Cdd:pfam01494  71 GMGLAFYNTRRRADLDFLTSPPRVTVYpqteLEPILVEHAEARGAQ-VRFG--------TEVLSLE-QDGDGVTAV--VR 138

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 919034376  201 VHLPDGE-TFQTKLLIGADGFNSLVRKQANIHTLQWDYEQWGLVSTLHFAEPTENVVA------WQRFLPTGPVAVLPL- 272
Cdd:pfam01494 139 DRRDGEEyTVRAKYLVGCDGGRSPVRKTLGIEFEGFEGVPFGSLDVLFDAPDLSDPVErafvhyLIYAPHSRGFMVGPWr 218

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 919034376  273 SETQSSLVWTTSPDEakrllklPKENfvdalnmalWDEDKKDSFavragqVAQDLINTVSPEgtsfrqlpptFTDIEDES 352
Cdd:pfam01494 219 SAGRERYYVQVPWDE-------EVEE---------RPEEFTDEE------LKQRLRSIVGID----------LALVEILW 266

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|....*..
gi 919034376  353 RAAFPLSLVHASHYVKPRLALIGDAAHRVHPLAGQGVNLGFGDVTCL 399
Cdd:pfam01494 267 KSIWGVASRVATRYRKGRVFLAGDAAHIHPPTGGQGLNTAIQDAFNL 313
 
Name Accession Description Interval E-value
COQ6 TIGR01989
ubiquinone biosynthesis monooxygenase COQ6; This model represents the monooxygenase ...
 45-473 0e+00

ubiquinone biosynthesis monooxygenase COQ6; This model represents the monooxygenase responsible for the 4-hydroxylateion of the phenol ring in the aerobic biosynthesis of ubiquinone


Pssm-ID: 273914 [Multi-domain]  Cd Length: 437  Bit Score: 526.63  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 919034376   45 FDVVISGGGMVGAAMACALGHANVFEDKKILLLEASPQKD------FKLPEKYGNRVCALSPATKKLLSGFGAWEEICNM 118
Cdd:TIGR01989   1 FDVVIVGGGPVGLALAAALGNNPLTKDLKVLLLDAVDNPKlksrnyEKPDGPYSNRVSSITPASISFFKKIGAWDHIQSD 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 919034376  119 RYQPVKRMQVWDACSDAFITLNHDDMTDDVAYIVENDVILAAIMKQF-DKIKHNVTVMYNSKAEMYTFPSQIQDgvqENL 197
Cdd:TIGR01989  81 RIQPFGRMQVWDGCSLALIRFDRDNGKEDMACIIENDNIQNSLYNRLqEYNGDNVKILNPARLISVTIPSKYPN---DNS 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 919034376  198 -WIKVHLPDGETFQTKLLIGADGFNSLVRKQANIHTLQWDYEQWGLVSTLHFAEPTENVVAWQRFLPTGPVAVLPLSETQ 276
Cdd:TIGR01989 158 nWVHITLSDGQVLYTKLLIGADGSNSNVRKAANIDTTGWNYNQHAVVATLKLEEATENDVAWQRFLPTGPIALLPLPDNN 237

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 919034376  277 SSLVWTTSPDEAKRLLKLPKENFVDALNMALWDEDKKDS---FAVRAGQVAQDLINTVSPEGTSFRQLPPTFTDIEDESR 353
Cdd:TIGR01989 238 STLVWSTSPEEALRLLSLPPEDFVDALNAAFDLGYSDHPysyLLDYAMEKLNEDIGFRTEGSKSCFQVPPRVIGVVDKSR 317

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 919034376  354 AAFPLSLVHASHYVKPRLALIGDAAHRVHPLAGQGVNLGFGDVTCLRDVLVQCLCNGGDLGSLSHLLQYETSRQRKVLPV 433
Cdd:TIGR01989 318 AAFPLGLGHADEYVTKRVALVGDAAHRVHPLAGQGVNLGFGDVASLVKALAEAVSVGADIGSISSLKPYERERYAKNVVL 397

                         410       420       430       440
                  ....*....|....*....|....*....|....*....|
gi 919034376  434 MFAMDGLKRLYGTDFPPVVVLRTLGLQATNSMKSLKDFFV 473
Cdd:TIGR01989 398 LGLVDKLHKLYATDFPPVVALRTFGLNLTNYIGPLKNFIM 437
Ubi-OHases TIGR01988
Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; This model represents a ...
 46-477 3.43e-150

Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; This model represents a family of FAD-dependent hydroxylases (monooxygenases) which are all believed to act in the aerobic ubiquinone biosynthesis pathway. A separate set of hydroxylases, as yet undiscovered, are believed to be active under anaerobic conditions. In E. coli three enzyme activities have been described, UbiB (which acts first at position 6, see TIGR01982), UbiH (which acts at position 4) and UbiF (which acts at position 5). UbiH and UbiF are similar to one another and form the basis of this subfamily. Interestingly, E. coli contains another hydroxylase gene, called visC, that is highly similar to UbiF, adjacent to UbiH and, when mutated, results in a phenotype similar to that of UbiH (which has also been named visB). Several other species appear to have three homologs in this family, although they assort themselves differently on phylogenetic trees (e.g. Xylella and Mesorhizobium) making it difficult to ascribe a specific activity to each one. Eukaryotes appear to have only a single homolog in this subfamily (COQ6) which complements UbiH, but also possess a non-orthologous gene, COQ7 which complements UbiF. [Biosynthesis of cofactors, prosthetic groups, and carriers, Menaquinone and ubiquinone]


Pssm-ID: 273913 [Multi-domain]  Cd Length: 385  Bit Score: 433.17  E-value: 3.43e-150
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 919034376   46 DVVISGGGMVGAAMACALGHANvfedKKILLLEASPQKDFKLPeKYGNRVCALSPATKKLLSGFGAWEEICNMRYQPVKR 125
Cdd:TIGR01988   1 DIVIVGGGMVGLALALALARSG----LKVALIEATPLPAPADP-GFDNRVSALSAASIRLLEKLGVWDKIEPARAQPIRD 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 919034376  126 MQVWDACSDAFITLNHDDM-TDDVAYIVENDVILAAIMKQFDKIKhNVTvmYNSKAEMYTFPSQIQdgvqenlWIKVHLP 204
Cdd:TIGR01988  76 IHVSDGGSFGALRFDADEIgLEALGYVVENRVLQQALWERLQELP-NVT--LLCPARVVELPRHSD-------HVELTLD 145

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 919034376  205 DGETFQTKLLIGADGFNSLVRKQANIHTLQWDYEQWGLVSTLHFAEPTENVvAWQRFLPTGPVAVLPLSETQSSLVWTTS 284
Cdd:TIGR01988 146 DGQQLRARLLVGADGANSKVRQLAGIPTTGWDYGQSAVVANVKHERPHQGT-AWERFTPTGPLALLPLPDNRSSLVWTLP 224

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 919034376  285 PDEAKRLLKLPKENFVDALNMAlwdedkkdsFAVRAGQVAQDlintvspegtsfrqlpptftdiedESRAAFPLSLVHAS 364
Cdd:TIGR01988 225 PEEAERLLALSDEEFLAELQRA---------FGSRLGAITLV------------------------GERHAFPLSLTHAK 271

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 919034376  365 HYVKPRLALIGDAAHRVHPLAGQGVNLGFGDVTCLRDVLVQCLCNGGDLGSLSHLLQYETSRQRKVLPVMFAMDGLKRLY 444
Cdd:TIGR01988 272 RYVAPRLALIGDAAHTIHPLAGQGLNLGLRDVAALAEVLEDARRRGEDIGSLRVLQRYERRRRFDNAAMLGATDGLNRLF 351

                         410       420       430
                  ....*....|....*....|....*....|...
gi 919034376  445 GTDFPPVVVLRTLGLQATNSMKSLKDFFVTQAT 477
Cdd:TIGR01988 352 SNDFPPLRLLRNLGLRLLNNLPPLKNFIARYAM 384
PRK07608 PRK07608
UbiH/UbiF family hydroxylase;
41-478 1.10e-84

UbiH/UbiF family hydroxylase;


Pssm-ID: 181057 [Multi-domain]  Cd Length: 388  Bit Score: 265.66  E-value: 1.10e-84
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 919034376  41 NSQLFDVVISGGGMVGAAMACALGHAnvfeDKKILLLEASPQKDfKLPEKYGNRVCALSPATKKLLSGFGAWEEICNMRY 120
Cdd:PRK07608   2 YHMKFDVVVVGGGLVGASLALALAQS----GLRVALLAPRAPPR-PADDAWDSRVYAISPSSQAFLERLGVWQALDAARL 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 919034376 121 QPVKRMQVW-DAcsDAFITLNHDDM-TDDVAYIVENDVILAAIMKQFdKIKHNVTVmYNSKAEMYTFPsqiQDGVQenlw 198
Cdd:PRK07608  77 APVYDMRVFgDA--HARLHFSAYQAgVPQLAWIVESSLIERALWAAL-RFQPNLTW-FPARAQGLEVD---PDAAT---- 145

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 919034376 199 ikVHLPDGETFQTKLLIGADGFNSLVRKQANIHTLQWDYEQWGLVStlHF-AEPTENVVAWQRFLPTGPVAVLPLSETQS 277
Cdd:PRK07608 146 --LTLADGQVLRADLVVGADGAHSWVRSQAGIKAERRPYRQTGVVA--NFkAERPHRGTAYQWFRDDGILALLPLPDGHV 221

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 919034376 278 SLVWTTSPDEAKRLLKLPKENFVDALnmalwdedkkdsfaVRAGQVAQDLINTVSPegtsfrqlpptftdiedesRAAFP 357
Cdd:PRK07608 222 SMVWSARTAHADELLALSPEALAARV--------------ERASGGRLGRLECVTP-------------------AAGFP 268

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 919034376 358 LSLVHASHYVKPRLALIGDAAHRVHPLAGQGVNLGFGDVTCLRDVLVQcLCNGGDLGSLSHLLQYETSRQRKVLPVMFAM 437
Cdd:PRK07608 269 LRLQRVDRLVAPRVALVGDAAHLIHPLAGQGMNLGLRDVAALADVLAG-REPFRDLGDLRLLRRYERARREDILALQVAT 347

                        410       420       430       440
                 ....*....|....*....|....*....|....*....|.
gi 919034376 438 DGLKRLYGTDFPPVVVLRTLGLQATNSMKSLKDFFVTQATN 478
Cdd:PRK07608 348 DGLQRLFALPGPLARWLRNAGMALVGALPLVKRWLVRHALG 388
PRK08850 PRK08850
2-octaprenyl-6-methoxyphenol hydroxylase; Validated
 43-476 1.55e-82

2-octaprenyl-6-methoxyphenol hydroxylase; Validated


Pssm-ID: 236341 [Multi-domain]  Cd Length: 405  Bit Score: 260.86  E-value: 1.55e-82
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 919034376  43 QLFDVVISGGGMVGAAMACALGHAnvfeDKKILLLEaSPQKDFKLPEKYGNRVCALSPATKKLLSGFGAWEEICNMRYQP 122
Cdd:PRK08850   3 QSVDVAIIGGGMVGLALAAALKES----DLRIAVIE-GQLPEEALNELPDVRVSALSRSSEHILRNLGAWQGIEARRAAP 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 919034376 123 VKRMQVWDACSDAFITLNHDDMTD-DVAYIVENDVILAAIMKQFDKIKhNVTVMYNSKAemytfpSQIQDGVQENlWIKv 201
Cdd:PRK08850  78 YIAMEVWEQDSFARIEFDAESMAQpDLGHIVENRVIQLALLEQVQKQD-NVTLLMPARC------QSIAVGESEA-WLT- 148

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 919034376 202 hLPDGETFQTKLLIGADGFNSLVRKQANIHTLQWDYEQWGLVSTLHFAEPtENVVAWQRFLPTGPVAVLPLSETQ-SSLV 280
Cdd:PRK08850 149 -LDNGQALTAKLVVGADGANSWLRRQMDIPLTHWDYGHSALVANVRTVDP-HNSVARQIFTPQGPLAFLPMSEPNmSSIV 226

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 919034376 281 WTTSPDEAKRLLKLPKENFVDALNMAlwdedkkdsFAVRAGqvaqdlintvspegtsfrqlpptFTDIEDEsRAAFPLSL 360
Cdd:PRK08850 227 WSTEPLRAEALLAMSDEQFNKALTAE---------FDNRLG-----------------------LCEVVGE-RQAFPLKM 273

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 919034376 361 VHASHYVKPRLALIGDAAHRVHPLAGQGVNLGFGDVTCLRDVLVQCLCNGGDLGSLSHLLQYETSRQRKVLPVMFAMDGL 440
Cdd:PRK08850 274 RYARDFVRERVALVGDAAHTIHPLAGQGVNLGLLDAASLAQEILALWQQGRDIGLKRNLRGYERWRKAEAAKMIAAMQGF 353

                        410       420       430
                 ....*....|....*....|....*....|....*.
gi 919034376 441 KRLYGTDFPPVVVLRTLGLQATNSMKSLKDFFVTQA 476
Cdd:PRK08850 354 RDLFSGSNPAKKLVRGIGMSLAGQLPGAKDEIMKRA 389
PRK05714 PRK05714
2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase; Provisional
 46-476 4.63e-82

2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase; Provisional


Pssm-ID: 168201 [Multi-domain]  Cd Length: 405  Bit Score: 259.76  E-value: 4.63e-82
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 919034376  46 DVVISGGGMVGAAMACALGHANVfedkKILLLEASP--QKDFKLPEKYGNRVCALSPATKKLLSGFGAWEEICNMRYQPV 123
Cdd:PRK05714   4 DLLIVGAGMVGSALALALQGSGL----EVLLLDGGPlsVKPFDPQAPFEPRVSALSAASQRILERLGAWDGIAARRASPY 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 919034376 124 KRMQVWDACSDAFITLNHDDMTDDV-AYIVENDVILAAIMKQFDKikHNVTVMYNSKAEmytfpsQIQDGVQEnlWIkVH 202
Cdd:PRK05714  80 SEMQVWDGSGTGQIHFSAASVHAEVlGHIVENRVVQDALLERLHD--SDIGLLANARLE------QMRRSGDD--WL-LT 148

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 919034376 203 LPDGETFQTKLLIGADGFNSLVRKQANIHTLQWDYEQWGLVSTLHFAEPtENVVAWQRFLPTGPVAVLPLS----ETQSS 278
Cdd:PRK05714 149 LADGRQLRAPLVVAADGANSAVRRLAGCATREWDYLHHAIVTSVRCSEP-HRATAWQRFTDDGPLAFLPLErdgdEHWCS 227

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 919034376 279 LVWTTSPDEAKRLLKLPKENFVDALNMAlwdedkkdsFAVRAGQVaqdlintvspegtsfrqlpptftdIEDESRAAFPL 358
Cdd:PRK05714 228 IVWSTTPEEAERLMALDDDAFCAALERA---------FEGRLGEV------------------------LSADPRLCVPL 274

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 919034376 359 SLVHASHYVKPRLALIGDAAHRVHPLAGQGVNLGFGDVTCLRDVLVQCLCNGGDLGSLSHLLQYETSRQRKVLPVMFAMD 438
Cdd:PRK05714 275 RQRHAKRYVEPGLALIGDAAHTIHPLAGQGVNLGFLDAAVLAEVLLHAAERGERLADVRVLSRFERRRMPHNLALMAAME 354

                        410       420       430
                 ....*....|....*....|....*....|....*...
gi 919034376 439 GLKRLYGTDFPPVVVLRTLGLQATNSMKSLKDFFVTQA 476
Cdd:PRK05714 355 GFERLFQADPLPLRWLRNTGLKLVDQMPEAKALFVRQA 392
PRK07333 PRK07333
ubiquinone biosynthesis hydroxylase;
45-476 6.48e-79

ubiquinone biosynthesis hydroxylase;


Pssm-ID: 180935 [Multi-domain]  Cd Length: 403  Bit Score: 251.44  E-value: 6.48e-79
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 919034376  45 FDVVISGGGMVGAAMACALGHANvfEDKKILLLEASPQKdfklPEKYGNRVCALSPATKKLLSGFGAWEEICNmRYQPVK 124
Cdd:PRK07333   2 CDVVIAGGGYVGLALAVALKQAA--PHLPVTVVDAAPAG----AWSRDPRASAIAAAARRMLEALGVWDEIAP-EAQPIT 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 919034376 125 RMQVWDA-CSDA----FITLNHD-DMTDDVAYIVENDVILAAIMKQFDKIkhNVTVMYNSKAEMYTfpsqiqdgvQENLW 198
Cdd:PRK07333  75 DMVITDSrTSDPvrpvFLTFEGEvEPGEPFAHMVENRVLINALRKRAEAL--GIDLREATSVTDFE---------TRDEG 143

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 919034376 199 IKVHLPDGETFQTKLLIGADGFNSLVRKQANIHTLQWDYEQWGLVSTLHFAEPtENVVAWQRFLPTGPVAVLPLSETQSS 278
Cdd:PRK07333 144 VTVTLSDGSVLEARLLVAADGARSKLRELAGIKTVGWDYGQSGIVCTVEHERP-HGGRAEEHFLPAGPFAILPLKGNRSS 222

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 919034376 279 LVWTTSPDEAKRLLKLPKENFVDALnmalwdedkKDSFAVRAGQvaqdlintVSPEGtsfrqlpptftdiedeSRAAFPL 358
Cdd:PRK07333 223 LVWTERTADAERLVALDDLVFEAEL---------EQRFGHRLGE--------LKVLG----------------KRRAFPL 269

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 919034376 359 SLVHASHYVKPRLALIGDAAHRVHPLAGQGVNLGFGDVTCLRDVLVQCLCNGGDLGSLSHLLQYETSRQRKVLPVMFAMD 438
Cdd:PRK07333 270 GLTLARSFVAPRFALVGDAAHGIHPIAGQGLNLGLKDVAALAEVVVEAARLGLDIGSLDVLERYQRWRRFDTVRMGVTTD 349

                        410       420       430
                 ....*....|....*....|....*....|....*...
gi 919034376 439 GLKRLYGTDFPPVVVLRTLGLQATNSMKSLKDFFVTQA 476
Cdd:PRK07333 350 VLNRLFSNDSTLLRSVRDIGLGLVDRLPKLKSFFIRQA 387
UbiH TIGR01984
2-polyprenyl-6-methoxyphenol 4-hydroxylase; This model represents the FAD-dependent ...
 46-476 1.92e-78

2-polyprenyl-6-methoxyphenol 4-hydroxylase; This model represents the FAD-dependent monoxygenase responsible for the second hydroxylation step in the aerobic ubiquinone bioynthetic pathway. The scope of this model is limited to the proteobacteria. This family is closely related to the UbiF hydroxylase which catalyzes the final hydroxylation step. The enzyme has also been named VisB due to a mutant VISible light sensitive phenotype. [Biosynthesis of cofactors, prosthetic groups, and carriers, Menaquinone and ubiquinone]


Pssm-ID: 273911 [Multi-domain]  Cd Length: 382  Bit Score: 249.54  E-value: 1.92e-78
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 919034376   46 DVVISGGGMVGAAMACALGHANvfeDKKILLLEA----SPQKDFKlpekygNRVCALSPATKKLLSGFGAWEEICNmRYQ 121
Cdd:TIGR01984   1 DVIIVGGGLVGLSLALALSRLG---KIKIALIEAnspsAAQPGFD------ARSLALSYGSKQILEKLGLWPKLAP-FAT 70

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 919034376  122 PVKRMQVWDACSDAFITLNHDDMTDDV-AYIVENDVILAAIMKQFDKikhnvtvmyNSKAEMYTfPSQIQDGVQENLWIK 200
Cdd:TIGR01984  71 PILDIHVSDQGHFGATHLRASEFGLPAlGYVVELADLGQALLSRLAL---------LTNIQLYC-PARYKEIIRNQDYVR 140

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 919034376  201 VHLPDGETFQTKLLIGADGFNSLVRKQANIHTLQWDYEQWGLVSTLHFAEPTENVvAWQRFLPTGPVAVLPLSE-TQSSL 279
Cdd:TIGR01984 141 VTLDNGQQLRAKLLIAADGANSKVRELLSIPTEEHDYNQTALIANIRHEQPHQGC-AFERFTPHGPLALLPLKDnYRSSL 219

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 919034376  280 VWTTSPDEAKRLLKLPKENFVDALnmalwdedkKDSFAVRAGQVAQDlintvspegtsfrqlpptftdiedESRAAFPLS 359
Cdd:TIGR01984 220 VWCLPSKQADTIANLPDAEFLAEL---------QQAFGWRLGKITQV------------------------GERKTYPLK 266

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 919034376  360 LVHASHYVKPRLALIGDAAHRVHPLAGQGVNLGFGDVTCLRDVLVQclcNGGDLGSLSHLLQYETSRQRKVLPVMFAMDG 439
Cdd:TIGR01984 267 LRIAETHVHPRVVLIGNAAQTLHPIAGQGFNLGLRDVETLAEVLID---ARIDLGTYALLQEYLRRRQFDQFITIGLTDG 343

                         410       420       430
                  ....*....|....*....|....*....|....*..
gi 919034376  440 LKRLYGTDFPPVVVLRTLGLQATNSMKSLKDFFVTQA 476
Cdd:TIGR01984 344 LNRLFSNHIPLLRALRNLGLLALENFPPLKKRLARQA 380
PRK08013 PRK08013
oxidoreductase; Provisional
 43-476 6.37e-78

oxidoreductase; Provisional


Pssm-ID: 236139 [Multi-domain]  Cd Length: 400  Bit Score: 248.81  E-value: 6.37e-78
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 919034376  43 QLFDVVISGGGMVGAAMACALGHANVfedkKILLLEASPQKDFKLPEKYGNRVCALSPATKKLLSGFGAWEEICNMRYQP 122
Cdd:PRK08013   2 QSVDVVIAGGGMVGLAVACGLQGSGL----RVAVLEQRVPEPLAADAPPALRVSAINAASEKLLTRLGVWQDILARRASC 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 919034376 123 VKRMQVWDACSDAFITLNHDDM-TDDVAYIVENDVILAAIMKQFDKIKHnVTVMYnskaemytfPSQIQD---GVQENLw 198
Cdd:PRK08013  78 YHGMEVWDKDSFGRIAFDDQSMgYSHLGHIIENSVIHYALWQKAQQSSD-ITLLA---------PAELQQvawGENEAF- 146

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 919034376 199 ikVHLPDGETFQTKLLIGADGFNSLVRKQANIHTLQWDYEQWGLVSTLHFAEPTENvVAWQRFLPTGPVAVLPLSETQ-S 277
Cdd:PRK08013 147 --LTLKDGSMLTARLVVGADGANSWLRNKADIPLTFWDYQHHALVATIRTEEPHDA-VARQVFHGDGILAFLPLSDPHlC 223

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 919034376 278 SLVWTTSPDEAKRLLKLPKENFVDALNMAlwdedkkdsFAVRAGQVAqdlintvspegtsfrqlpptftdIEDEsRAAFP 357
Cdd:PRK08013 224 SIVWSLSPEEAQRMQQAPEEEFNRALAIA---------FDNRLGLCE-----------------------LESE-RQVFP 270

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 919034376 358 LSLVHASHYVKPRLALIGDAAHRVHPLAGQGVNLGFGDVTCLRDVLVQCLCNGGDLGSLSHLLQYETSRQRKVlPVMFA- 436
Cdd:PRK08013 271 LTGRYARQFAAHRLALVGDAAHTIHPLAGQGVNLGFMDAAELIAELRRLHRQGKDIGQHLYLRRYERSRKHSA-ALMLAg 349

                        410       420       430       440
                 ....*....|....*....|....*....|....*....|
gi 919034376 437 MDGLKRLYGTDFPPVVVLRTLGLQATNSMKSLKDFFVTQA 476
Cdd:PRK08013 350 MQGFRDLFAGNNPAKKLLRDIGLKLADTLPGVKPQLIRQA 389
PRK07364 PRK07364
FAD-dependent hydroxylase;
45-471 2.99e-76

FAD-dependent hydroxylase;


Pssm-ID: 236001 [Multi-domain]  Cd Length: 415  Bit Score: 244.93  E-value: 2.99e-76
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 919034376  45 FDVVISGGGMVGAAMACALGHANVfedkKILLLEASPQ-KDFKLPEKYgnrvcALSPATKKLLSGFGAWEEICNmRYQPV 123
Cdd:PRK07364  19 YDVAIVGGGIVGLTLAAALKDSGL----RIALIEAQPAeAAAAKGQAY-----ALSLLSARIFEGIGVWEKILP-QIGKF 88

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 919034376 124 KRMQVWDACSDAFITLNHDDM-TDDVAYIVENDVILAAIMKQFDKIKhNVTvmYNSKAEMYTFPSQiQDGVQENLWIKvh 202
Cdd:PRK07364  89 RQIRLSDADYPGVVKFQPTDLgTEALGYVGEHQVLLEALQEFLQSCP-NIT--WLCPAEVVSVEYQ-QDAATVTLEIE-- 162

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 919034376 203 lPDGETFQTKLLIGADGFNSLVRKQANIHTLQWDYEQWGLVSTLHFAEPtENVVAWQRFLPTGPVAVLPLSETQSSLVWT 282
Cdd:PRK07364 163 -GKQQTLQSKLVVAADGARSPIRQAAGIKTKGWKYWQSCVTATVKHEAP-HNDIAYERFWPSGPFAILPLPGNRCQIVWT 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 919034376 283 TSPDEAKRLLKLPKENFVDALNMALWDedkkdsfavRAGQVAqdLINtvspegtsfrqlpptftdiedeSRAAFPLSLVH 362
Cdd:PRK07364 241 APHAQAKALLALPEAEFLAELQQRYGD---------QLGKLE--LLG----------------------DRFLFPVQLMQ 287

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 919034376 363 ASHYVKPRLALIGDAAHRVHPLAGQGVNLGFGDVTCLRDVLVQCLCNGGDLGSLSHLLQYETSRQRKVLPVMFAMDGLKR 442
Cdd:PRK07364 288 SDRYVQHRLALVGDAAHCCHPVGGQGLNLGIRDAAALAQVLQTAHQRGEDIGSLAVLKRYERWRKRENWLILGFTDLLDR 367

                        410       420
                 ....*....|....*....|....*....
gi 919034376 443 LYGTDFPPVVVLRTLGLQATNSMKSLKDF 471
Cdd:PRK07364 368 LFSNQWWPLVVVRRLGLWLLRHVPPLKRL 396
ubiF PRK08020
2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase; Reviewed
 40-469 2.07e-74

2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase; Reviewed


Pssm-ID: 181199 [Multi-domain]  Cd Length: 391  Bit Score: 239.11  E-value: 2.07e-74
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 919034376  40 DNSQLFDVVISGGGMVGAAMACALGHANVfedkKILLLEASPQKDFKLPEKYGNRVCALSPATKKLLSGFGAWEEICNMR 119
Cdd:PRK08020   1 MTNQPTDIAIVGGGMVGAALALGLAQHGF----SVAVLEHAAPAPFDADSQPDVRISAISAASVALLKGLGVWDAVQAMR 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 919034376 120 YQPVKRMQVWDAcSDAFITLNHDDMT-DDVAYIVENDVILAAIMKQFDKiKHNVTVMYnskaemytfPSQIQDGVQENLW 198
Cdd:PRK08020  77 SHPYRRLETWEW-ETAHVVFDAAELKlPELGYMVENRVLQLALWQALEA-HPNVTLRC---------PASLQALQRDDDG 145

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 919034376 199 IKVHLPDGETFQTKLLIGADGFNSLVRKQANIHTLQWDYEQWGLVSTLHFAEPTENVVaWQRFLPTGPVAVLPLSETQSS 278
Cdd:PRK08020 146 WELTLADGEEIQAKLVIGADGANSQVRQMAGIGVHGWQYRQSCMLISVKCENPPGDST-WQQFTPSGPRAFLPLFDNWAS 224

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 919034376 279 LVWTTSPDEAKRLlklpkenfvDALNMALWDEDKKDSFAVRAGqvaqdlinTVSPEGTsfrqlpptftdiedesrAAFPL 358
Cdd:PRK08020 225 LVWYDSPARIRQL---------QAMSMAQLQQEIAAHFPARLG--------AVTPVAA-----------------GAFPL 270

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 919034376 359 SLVHASHYVKPRLALIGDAAHRVHPLAGQGVNLGFGDVTCLRDVLVQCLCNGGDLGSLSHLLQYETSRQRKVLPVMFAMD 438
Cdd:PRK08020 271 TRRHALQYVQPGLALVGDAAHTINPLAGQGVNLGYRDVDALLDVLVNARSYGEAWASEAVLKRYQRRRMADNLLMQSGMD 350

                        410       420       430
                 ....*....|....*....|....*....|.
gi 919034376 439 GLKRLYGTDFPPVVVLRTLGLQATNSMKSLK 469
Cdd:PRK08020 351 LFYAGFSNNLPPLRFARNLGLMAAQRAGVLK 381
PRK08849 PRK08849
2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase; Provisional
 45-469 1.22e-70

2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase; Provisional


Pssm-ID: 181564 [Multi-domain]  Cd Length: 384  Bit Score: 229.27  E-value: 1.22e-70
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 919034376  45 FDVVISGGGMVGAAMAcaLGHANvfEDKKILLLEASPQKDFKLPEKYGNRVCALSPATKKLLSGFGAWEEICNMRYQPVK 124
Cdd:PRK08849   4 YDIAVVGGGMVGAATA--LGFAK--QGRSVAVIEGGEPKAFEPSQPMDIRVSAISQTSVDLLESLGAWSSIVAMRVCPYK 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 919034376 125 RMQVWD--ACSDAFitlNHDDMT-DDVAYIVENDVILAAIMKQFDKIKhNVTVMYNSKAEMYTFPSQIQdgvqenlwiKV 201
Cdd:PRK08849  80 RLETWEhpECRTRF---HSDELNlDQLGYIVENRLIQLGLWQQFAQYP-NLTLMCPEKLADLEFSAEGN---------RV 146

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 919034376 202 HLPDGETFQTKLLIGADGFNSLVRKQANIHTLQWDYEQWGLVSTLHFAEPTENvVAWQRFLPTGPVAVLPLSETQSSLVW 281
Cdd:PRK08849 147 TLESGAEIEAKWVIGADGANSQVRQLAGIGITAWDYRQHCMLINVETEQPQQD-ITWQQFTPSGPRSFLPLCGNQGSLVW 225

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 919034376 282 TTSPDEAKRLLKLPKEnfvdalnmalwdedkkdsfavragQVAQDLIntvspegtsfRQLPPTFTDIEDESRAAFPLSLV 361
Cdd:PRK08849 226 YDSPKRIKQLSAMNPE------------------------QLRSEIL----------RHFPAELGEIKVLQHGSFPLTRR 271

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 919034376 362 HASHYVKPRLALIGDAAHRVHPLAGQGVNLGFGDVtclrDVLVQCLCNGGDLgSLSHLLQYETSRQRKVLPVMFAMDGLK 441
Cdd:PRK08849 272 HAQQYVKNNCVLLGDAAHTINPLAGQGVNLGFKDV----DVLLAETEKQGVL-NDASFARYERRRRPDNLLMQTGMDLFY 346

                        410       420
                 ....*....|....*....|....*...
gi 919034376 442 RLYGTDFPPVVVLRTLGLQATNSMKSLK 469
Cdd:PRK08849 347 KTFSNSLTPLKFVRNAALKLAENSGPLK 374
PRK05732 PRK05732
2-octaprenyl-6-methoxyphenyl hydroxylase; Validated
 42-476 4.89e-70

2-octaprenyl-6-methoxyphenyl hydroxylase; Validated


Pssm-ID: 235584 [Multi-domain]  Cd Length: 395  Bit Score: 228.20  E-value: 4.89e-70
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 919034376  42 SQLFDVVISGGGMVGAAMACALGHANVFEdKKILLLEA-SPQKDFklPEKYGNRVCALSPATKKLLSGFGAWEEIcNMRY 120
Cdd:PRK05732   1 MSRMDVIIVGGGMAGATLALALSRLSHGG-LPVALIEAfAPESDA--HPGFDARAIALAAGTCQQLARLGVWQAL-ADCA 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 919034376 121 QPVKRMQVWDACSDAFITLNHDDM-TDDVAYIVEN-DVILAAimkqFDKIKHNVTVMYNSKAEMYTFpSQIQDGVQenlw 198
Cdd:PRK05732  77 TPITHIHVSDRGHAGFVRLDAEDYgVPALGYVVELhDVGQRL----FALLDKAPGVTLHCPARVANV-ERTQGSVR---- 147

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 919034376 199 ikVHLPDGETFQTKLLIGADGFNSLVRKQANIHTLQWDYEQWGLVSTLHFAEPtENVVAWQRFLPTGPVAVLPLSETQSS 278
Cdd:PRK05732 148 --VTLDDGETLTGRLLVAADGSHSALREALGIDWQQHPYEQVAVIANVTTSEA-HQGRAFERFTEHGPLALLPMSDGRCS 224

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 919034376 279 LVWTTSPDEAKRLLKLPKENFVDALNMAlwdedkkdsFAVRAGQvaqdlintvspegtsFRQLPPtftdiedesRAAFPL 358
Cdd:PRK05732 225 LVWCHPLEDAEEVLSWSDAQFLAELQQA---------FGWRLGR---------------ITHAGK---------RSAYPL 271

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 919034376 359 SLVHASHYVKPRLALIGDAAHRVHPLAGQGVNLGFGDVTCLRDVLVQCLCNGGDLGSLSHLLQYETSRQ--RKvLPVMFA 436
Cdd:PRK05732 272 ALVTAAQQISHRLALVGNAAQTLHPIAGQGFNLGLRDVMSLAETLTQALARGEDIGDYAVLQRYQQRRQqdRE-ATIGFT 350

                        410       420       430       440
                 ....*....|....*....|....*....|....*....|
gi 919034376 437 mDGLKRLYGTDFPPVVVLRTLGLQATNSMKSLKDFFVTQA 476
Cdd:PRK05732 351 -DGLVRLFANRWAPLVVGRNLGLMAMDLLPPARDWLARRT 389
PRK08773 PRK08773
UbiH/UbiF family hydroxylase;
46-477 1.43e-65

UbiH/UbiF family hydroxylase;


Pssm-ID: 181552 [Multi-domain]  Cd Length: 392  Bit Score: 216.27  E-value: 1.43e-65
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 919034376  46 DVVISGGGMVGAAMACALGHANVfedkKILLLEASPQKDFKlPEKYGNRVCALSPATKKLLSGFGAWEEICNMRYQPVKR 125
Cdd:PRK08773   8 DAVIVGGGVVGAACALALADAGL----SVALVEGREPPRWQ-ADQPDLRVYAFAADNAALLDRLGVWPAVRAARAQPYRR 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 919034376 126 MQVWDACSDAFITLNHDDM-TDDVAYIVENDVILAAIMkqfdkikhnvTVMYNSKAEMYTfPSQIQDGVQENLWIKVHLP 204
Cdd:PRK08773  83 MRVWDAGGGGELGFDADTLgREQLGWIVENDLLVDRLW----------AALHAAGVQLHC-PARVVALEQDADRVRLRLD 151

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 919034376 205 DGETFQTKLLIGADGFNSLVRKQANIHTLQWDYEQWGLVSTLHFAEPTEnVVAWQRFLPTGPVAVLPLSETQSSLVWTTS 284
Cdd:PRK08773 152 DGRRLEAALAIAADGAASTLRELAGLPVSRHDYAQRGVVAFVDTEHPHQ-ATAWQRFLPTGPLALLPFADGRSSIVWTLP 230

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 919034376 285 PDEAKRLLKLPKENFVDALNMAlwdedkkdsFAVRAGQVaqdliNTVSPegtsfrqlpptftdiedesRAAFPLSLVHAS 364
Cdd:PRK08773 231 DAEAERVLALDEAAFSRELTQA---------FAARLGEV-----RVASP-------------------RTAFPLRRQLVQ 277

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 919034376 365 HYVKPRLALIGDAAHRVHPLAGQGVNLGFGDVTCLRDVLVQCLCNGGDLGSLSHLLQYETSRQRKVLPVMFAMDGLKRLY 444
Cdd:PRK08773 278 QYVSGRVLTLGDAAHVVHPLAGQGVNLGLRDVAALQQLVRQAHARRADWAAPHRLQRWARTRRSDNTVAAYGFDAINRVF 357

                        410       420       430
                 ....*....|....*....|....*....|...
gi 919034376 445 GTDFPPVVVLRTLGLQATNSMKSLKDFFVTQAT 477
Cdd:PRK08773 358 SNDEMHLTLLRGSVLGLAGKLPPLVDALWKRAS 390
UbiH COG0654
2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases [Coenzyme ...
 45-469 1.76e-60

2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases [Coenzyme transport and metabolism, Energy production and conversion]; 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases is part of the Pathway/BioSystem: Ubiquinone biosynthesis


Pssm-ID: 440419 [Multi-domain]  Cd Length: 326  Bit Score: 200.93  E-value: 1.76e-60
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 919034376  45 FDVVISGGGMVGAAMACALGHANVfedkKILLLEASPqkdfklPEKYGNRVCALSPATKKLLSGFGAWEEICnMRYQPVK 124
Cdd:COG0654    4 TDVLIVGGGPAGLALALALARAGI----RVTVVERAP------PPRPDGRGIALSPRSLELLRRLGLWDRLL-ARGAPIR 72

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 919034376 125 RMQVWDACSDAFIT-LNHDDMTDDVAYIVENDVILAAIMKQFDKikHNVTVMYNSKAEMYTfpsQIQDGVQenlwikVHL 203
Cdd:COG0654   73 GIRVRDGSDGRVLArFDAAETGLPAGLVVPRADLERALLEAARA--LGVELRFGTEVTGLE---QDADGVT------VTL 141

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 919034376 204 PDGETFQTKLLIGADGFNSLVRKQANIHTLQWDYEQWGLVSTLHfaeptenvvawqrflptgpvavlplsetqsslvwtt 283
Cdd:COG0654  142 ADGRTLRADLVVGADGARSAVRRLLGIGFTGRDYPQRALWAGVR------------------------------------ 185

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 919034376 284 spdeakrllklpkenfvdalnMALWDEdkkdsfavragqvaqdlintvspegtsFRQLPPTFTDIED-ESRAAFPLSLVH 362
Cdd:COG0654  186 ---------------------TELRAR---------------------------LAAAGPRLGELLElSPRSAFPLRRRR 217

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 919034376 363 ASHYVKPRLALIGDAAHRVHPLAGQGVNLGFGDVTCLRDVLVQCLcNGGDLGSLshLLQYETSRQRKVLPVMFAMDGLKR 442
Cdd:COG0654  218 AERWRRGRVVLLGDAAHTMHPLGGQGANLALRDAAALAWKLAAAL-RGRDDEAA--LARYERERRPRAARVQRAADALGR 294

                        410       420
                 ....*....|....*....|....*..
gi 919034376 443 LYGTDFPPVVVLRTLGLQATNSMKSLK 469
Cdd:COG0654  295 LFHPDSPPLRLLRNAGLRLLDRLPPLK 321
PRK09126 PRK09126
FAD-dependent hydroxylase;
42-477 1.08e-53

FAD-dependent hydroxylase;


Pssm-ID: 236385 [Multi-domain]  Cd Length: 392  Bit Score: 185.15  E-value: 1.08e-53
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 919034376  42 SQLFDVVISGGGMVGAAMACALGHANVfedkKILLLEASPQKDFKLPEkYGNRVCALSPATKKLLSGFGAWEEICNMRYQ 121
Cdd:PRK09126   1 MMHSDIVVVGAGPAGLSFARSLAGSGL----KVTLIERQPLAALADPA-FDGREIALTHASREILQRLGAWDRIPEDEIS 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 919034376 122 PVKRMQVWDACSDAFITLNHDDM-TDDVAYIVENDVILAAImkqFDKIKH--NVTVMYNSKAEMYTfpsQIQDGVQenlw 198
Cdd:PRK09126  76 PLRDAKVLNGRSPFALTFDARGRgADALGYLVPNHLIRRAA---YEAVSQqdGIELLTGTRVTAVR---TDDDGAQ---- 145

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 919034376 199 ikVHLPDGETFQTKLLIGADGFNSLVRKQANIHTLQWDYEQWGLVSTLHFAEPTENVvAWQRFLPTGPVAVLPLSETQSS 278
Cdd:PRK09126 146 --VTLANGRRLTARLLVAADSRFSATRRQLGIGADMHDFGRTMLVCRMRHELPHHHT-AWEWFGYGQTLALLPLNGHLSS 222

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 919034376 279 LVWTTSPDEAKRLLKLPKENFvdalnmalwDEDKKDSFAVRAGQVAQdlintVSpegtsfrqlpptftdiedeSRAAFPL 358
Cdd:PRK09126 223 LVLTLPPDQIEALLALDPEAF---------AAEVTARFKGRLGAMRL-----VS-------------------SRHAYPL 269

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 919034376 359 SLVHASHYVKPRLALIGDAAHRVHPLAGQGVNLGFGDVTCLRDVLVQCLCNGGDLGSLSHLLQYETSRQRKVLPVMFAMD 438
Cdd:PRK09126 270 VAVYAHRFVAKRFALIGDAAVGMHPVTAHGFNLGLKGQDILARLILAAARRGQDIGAASLLERYERKHRLATRPLYHATN 349

                        410       420       430
                 ....*....|....*....|....*....|....*....
gi 919034376 439 GLKRLYGTDFPPVVVLRTLGLQATNSMKSLKDFFVTQAT 477
Cdd:PRK09126 350 AIAALYTDDRPPARLLRRAVLRAANRFPPLKQAIAKQLT 388
PRK07494 PRK07494
UbiH/UbiF family hydroxylase;
41-472 3.31e-46

UbiH/UbiF family hydroxylase;


Pssm-ID: 181001 [Multi-domain]  Cd Length: 388  Bit Score: 165.08  E-value: 3.31e-46
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 919034376  41 NSQLFDVVISGGGMVGAAMACALGHA--NVfedkkILLLEASPQKDfklpekygNRVCALSPATKKLLSGFGAWEEiCNM 118
Cdd:PRK07494   4 EKEHTDIAVIGGGPAGLAAAIALARAgaSV-----ALVAPEPPYAD--------LRTTALLGPSIRFLERLGLWAR-LAP 69

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 919034376 119 RYQPVKRMQVWDACSDAF----ITLNHDDMTDDV-AYIVENDVILAAIMKQFDKIKhNVTVMYNSKAEMYTFPSQIqdgv 193
Cdd:PRK07494  70 HAAPLQSMRIVDATGRLIrapeVRFRAAEIGEDAfGYNIPNWLLNRALEARVAELP-NITRFGDEAESVRPREDEV---- 144

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 919034376 194 qenlwiKVHLPDGETFQTKLLIGADGFNSLVRKQANIHTLQWDYEQWGLVSTLHFAEPTENVVAwqRF-LPTGPVAVLPL 272
Cdd:PRK07494 145 ------TVTLADGTTLSARLVVGADGRNSPVREAAGIGVRTWSYPQKALVLNFTHSRPHQNVST--EFhTEGGPFTQVPL 216

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 919034376 273 SETQSSLVWTTSPDEAKRLLKLPKenfvdalnmalwdedkkDSFAVRAGQVAQDLINTVSPEGtsfrqlpptftdiedeS 352
Cdd:PRK07494 217 PGRRSSLVWVVRPAEAERLLALSD-----------------AALSAAIEERMQSMLGKLTLEP----------------G 263

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 919034376 353 RAAFPLSLVHASHYVKPRLALIGDAAHRVHPLAGQGVNLGFGDVTCLRDVLVQclcNGGDLGSLSHLLQYETSRQRKVLP 432
Cdd:PRK07494 264 RQAWPLSGQVAHRFAAGRTALVGEAAHVFPPIGAQGLNLGLRDVATLVEIVED---RPEDPGSAAVLAAYDRARRPDILS 340

                        410       420       430       440
                 ....*....|....*....|....*....|....*....|
gi 919034376 433 VMFAMDGLKRLYGTDFPPVVVLRTLGLQATNSMKSLKDFF 472
Cdd:PRK07494 341 RTASVDLLNRSLLSDFLPVQDLRAAGLHLLYSFGPLRRLF 380
PRK06996 PRK06996
UbiH/UbiF/VisC/COQ6 family ubiquinone biosynthesis hydroxylase;
45-461 6.54e-43

UbiH/UbiF/VisC/COQ6 family ubiquinone biosynthesis hydroxylase;


Pssm-ID: 235905 [Multi-domain]  Cd Length: 398  Bit Score: 156.39  E-value: 6.54e-43
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 919034376  45 FDVVISGGGMVGAAMACALGHANVFEDKKILLLEASPqkdfklPEKYGN--RVCALSPATKKLLSGFGAWEeicnMRYQP 122
Cdd:PRK06996  12 FDIAIVGAGPVGLALAGWLARRSATRALSIALIDARE------PAASANdpRAIALSHGSRVLLETLGAWP----ADATP 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 919034376 123 VKRMQVWDACSDAFITLNHDDMtdDVA---YIVENDVILAAIMKQFDKIKhnVTVMYNSKAEMytfPSQIQDGVQENLwi 199
Cdd:PRK06996  82 IEHIHVSQRGHFGRTLIDRDDH--DVPalgYVVRYGSLVAALARAVRGTP--VRWLTSTTAHA---PAQDADGVTLAL-- 152

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 919034376 200 kvHLPDGE-TFQTKLLIGADG--FNSLVRKQANIhTLQWDYEQWGLVSTLHFAEPTENVvAWQRFLPTGPVAVLPLSETQ 276
Cdd:PRK06996 153 --GTPQGArTLRARIAVQAEGglFHDQKADAGDS-ARRRDYGQTAIVGTVTVSAPRPGW-AWERFTHEGPLALLPLGGPR 228

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 919034376 277 S---SLVWTTSPDEAKRLLKLPKENFVDALNMAlwdedkkdsFAVRAGQvaqdlintvspegtsFRQLPPtftdiedesR 353
Cdd:PRK06996 229 QadyALVWCCAPDEAARRAALPDDAFLAELGAA---------FGTRMGR---------------FTRIAG---------R 275

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 919034376 354 AAFPLSLVHASHYVKPRLALIGDAAHRVHPLAGQGVNLGFGDVTCLRDVLVQCLCNGGDLgslshllqyETSRQRKVLPV 433
Cdd:PRK06996 276 HAFPLGLNAARTLVNGRIAAVGNAAQTLHPVAGQGLNLGLRDAHTLADALSDHGATPLAL---------ATFAARRALDR 346

                        410       420       430
                 ....*....|....*....|....*....|.
gi 919034376 434 MF---AMDGLKRLYGTDFPPVVVLRTLGLQA 461
Cdd:PRK06996 347 RVtigATDLLPRLFTVDSRPLAHLRGAALTA 377
PRK06617 PRK06617
2-octaprenyl-6-methoxyphenyl hydroxylase; Validated
 44-476 3.39e-30

2-octaprenyl-6-methoxyphenyl hydroxylase; Validated


Pssm-ID: 168629 [Multi-domain]  Cd Length: 374  Bit Score: 120.80  E-value: 3.39e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 919034376  44 LFDVVISGGGMVGAAMACALGHANVfedkKILLLEAspqKDFKLPEKYGN-RVCALSPATKKLLSGFGAWEEIcnmrYQP 122
Cdd:PRK06617   1 MSNTVILGCGLSGMLTALSFAQKGI----KTTIFES---KSVKSPEFFKDiRTTALTPHSKNFLFSIDIWEEL----EKF 69

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 919034376 123 VKRMQvwdacsDAFITLNHDDMTDDVAYivENDVILAAIMKQFDKIKHNVTVMYNSKAEMYTFPSQIQDGVQENLWIKVH 202
Cdd:PRK06617  70 VAEMQ------DIYVVDNKASEILDLRN--DADAVLGYVVKNSDFKKILLSKITNNPLITLIDNNQYQEVISHNDYSIIK 141

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 919034376 203 LpDGETFQTKLLIGADGFNSLVRKQANIHTLQWDYeQWGLVSTLHFAEPTENVvAWQRFLPTGPVAVLPL-SETQSSLVW 281
Cdd:PRK06617 142 F-DDKQIKCNLLIICDGANSKVRSHYFANEIEKPY-QTALTFNIKHEKPHENC-AMEHFLPLGPFALLPLkDQYASSVIW 218

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 919034376 282 TTSPDEAKRLLKLPKENfVDALnmalwdedkkdsfavragqvaqdlinTVSPEGTSFRQLPPtftdieDESRAAFPLSLV 361
Cdd:PRK06617 219 STSSDQAALIVNLPVEE-VRFL--------------------------TQRNAGNSLGKITI------DSEISSFPLKAR 265

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 919034376 362 HASHYVKPRLALIGDAAHRVHPLAGQGVNLGFGDVtclrDVLVQCLCNGGDLGslshllQYETSRQRKVLpVMFAM-DGL 440
Cdd:PRK06617 266 IANRYFHNRIVLIADTAHTVHPLAGQGLNQGIKDI----EILSMIVSNNGTLQ------EYQKLRQEDNF-IMYKLtDEL 334

                        410       420       430
                 ....*....|....*....|....*....|....*.
gi 919034376 441 KRLYGTDFPPVVVLRTLGLQATNSMKSLKDFFVTQA 476
Cdd:PRK06617 335 NNIFSNYSKNLRCLRQIGFKVINNFKPIKNLITSYA 370
FAD_binding_3 pfam01494
FAD binding domain; This domain is involved in FAD binding in a number of enzymes.
 46-399 3.57e-14

FAD binding domain; This domain is involved in FAD binding in a number of enzymes.


Pssm-ID: 396193 [Multi-domain]  Cd Length: 348  Bit Score: 73.51  E-value: 3.57e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 919034376   46 DVVISGGGMVGAAMACALGHANVfedkKILLLEaspqkdfKLPEKYGN-RVCALSPATKKLLSGFGAWEEICNMRYqPVK 124
Cdd:pfam01494   3 DVLIVGGGPAGLMLALLLARAGV----RVVLVE-------RHATTSVLpRAHGLNQRTMELLRQAGLEDRILAEGV-PHE 70

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 919034376  125 RMQVWDACSDAFITLNHDDMTDDVAYI----VENDVILAAIMKQFDkIKHNvtvmynskAEMYTFPsQIQDGVQENlwIK 200
Cdd:pfam01494  71 GMGLAFYNTRRRADLDFLTSPPRVTVYpqteLEPILVEHAEARGAQ-VRFG--------TEVLSLE-QDGDGVTAV--VR 138

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 919034376  201 VHLPDGE-TFQTKLLIGADGFNSLVRKQANIHTLQWDYEQWGLVSTLHFAEPTENVVA------WQRFLPTGPVAVLPL- 272
Cdd:pfam01494 139 DRRDGEEyTVRAKYLVGCDGGRSPVRKTLGIEFEGFEGVPFGSLDVLFDAPDLSDPVErafvhyLIYAPHSRGFMVGPWr 218

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 919034376  273 SETQSSLVWTTSPDEakrllklPKENfvdalnmalWDEDKKDSFavragqVAQDLINTVSPEgtsfrqlpptFTDIEDES 352
Cdd:pfam01494 219 SAGRERYYVQVPWDE-------EVEE---------RPEEFTDEE------LKQRLRSIVGID----------LALVEILW 266

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|....*..
gi 919034376  353 RAAFPLSLVHASHYVKPRLALIGDAAHRVHPLAGQGVNLGFGDVTCL 399
Cdd:pfam01494 267 KSIWGVASRVATRYRKGRVFLAGDAAHIHPPTGGQGLNTAIQDAFNL 313
FixC COG0644
Dehydrogenase (flavoprotein) [Energy production and conversion];
52-433 1.32e-12

Dehydrogenase (flavoprotein) [Energy production and conversion];


Pssm-ID: 440409 [Multi-domain]  Cd Length: 281  Bit Score: 68.07  E-value: 1.32e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 919034376  52 GGMVGAAMACALGHANVfedkKILLLEASPQKDFKlpekygnrVC--ALSPATKKLLSGFGAWEEICNmryqPVKRMQVW 129
Cdd:COG0644    1 AGPAGSAAARRLARAGL----SVLLLEKGSFPGDK--------ICggGLLPRALEELEPLGLDEPLER----PVRGARFY 64

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 919034376 130 dACSDAFITLNHDDmtdDVAYIVEndvilaaiMKQFDK------IKHNVTVMYNSKAemytfpsqiQDGVQENLWIKVHL 203
Cdd:COG0644   65 -SPGGKSVELPPGR---GGGYVVD--------RARFDRwlaeqaEEAGAEVRTGTRV---------TDVLRDDGRVVVRT 123

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 919034376 204 PDGETFQTKLLIGADGFNSLVRKQANIHTlqwdyeqwglvstlHFAEPTENVVAwqrflptgpvavlplsetqsslvwtt 283
Cdd:COG0644  124 GDGEEIRADYVVDADGARSLLARKLGLKR--------------RSDEPQDYALA-------------------------- 163

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 919034376 284 spdeAKRLLKLPKENFVDALNMALWdedkkdsfavragqvaqdlINTVSPEGTSFrqlppTFTDIEDESRAAFPLSlVHA 363
Cdd:COG0644  164 ----IKEHWELPPLEGVDPGAVEFF-------------------FGEGAPGGYGW-----VFPLGDGRVSVGIPLG-GPR 214

                        330       340       350       360       370       380       390
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 919034376 364 SHYVKPRLALIGDAAHRVHPLAGQGVNLGFGDVTCLRDVLVQCLcnGGDLGSLSHLLQYETsRQRKVLPV 433
Cdd:COG0644  215 PRLVGDGVLLVGDAAGFVDPLTGEGIHLAMKSGRLAAEAIAEAL--EGGDFSAEALAEYER-RLRELLKA 281
PRK06834 PRK06834
hypothetical protein; Provisional
 46-395 2.35e-10

hypothetical protein; Provisional


Pssm-ID: 235870 [Multi-domain]  Cd Length: 488  Bit Score: 62.34  E-value: 2.35e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 919034376  46 DVVISGGGMVGAAMACALGHANVfedkKILLLEASPQkdfklPEKYGNRVCALSPATKKLLSGFGAWEeicnmRYqpVKR 125
Cdd:PRK06834   5 AVVIAGGGPTGLMLAGELALAGV----DVAIVERRPN-----QELVGSRAGGLHARTLEVLDQRGIAD-----RF--LAQ 68

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 919034376 126 MQVWDACSDAFITLnhdDMTDdvaYIVENDVILAAIMKQFDKI------KHNVTVMYNskAEMYTFpSQIQDGVQenlwi 199
Cdd:PRK06834  69 GQVAQVTGFAATRL---DISD---FPTRHNYGLALWQNHIERIlaewvgELGVPIYRG--REVTGF-AQDDTGVD----- 134

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 919034376 200 kVHLPDGETFQTKLLIGADGFNSLVRKQANIHTLQWDYEQWGLVSTLHFAEPTE--------NVVAWQRFLPTGPVAVLp 271
Cdd:PRK06834 135 -VELSDGRTLRAQYLVGCDGGRSLVRKAAGIDFPGWDPTTSYLIAEVEMTEEPEwgvhrdalGIHAFGRLEDEGPVRVM- 212

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 919034376 272 LSETQssLVWTTSPDeakrllklpkenfVDALNMALwdedkkdsfavragqvaqdlintVSPEGTSFRQLPPT----FTD 347
Cdd:PRK06834 213 VTEKQ--VGATGEPT-------------LDDLREAL-----------------------IAVYGTDYGIHSPTwisrFTD 254

                        330       340       350       360
                 ....*....|....*....|....*....|....*....|....*...
gi 919034376 348 IedeSRaafplslvHASHYVKPRLALIGDAAHRVHPLAGQGVNLGFGD 395
Cdd:PRK06834 255 M---AR--------QAASYRDGRVLLAGDAAHVHSPVGGQGLNTGVQD 291
PRK07045 PRK07045
putative monooxygenase; Reviewed
 200-407 9.08e-09

putative monooxygenase; Reviewed


Pssm-ID: 136171 [Multi-domain]  Cd Length: 388  Bit Score: 57.22  E-value: 9.08e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 919034376 200 KVHLPDGETFQTKLLIGADGFNSLVRKQA-NIHTLQWDYEQWGLVSTLHFaepTENVVAWQRFL---PTGPVAVLPLSET 275
Cdd:PRK07045 143 SVTLSDGERVAPTVLVGADGARSMIRDDVlRMPAERVPYATPMAFGTIAL---TDSVRECNRLYvdsNQGLAYFYPIGDQ 219

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 919034376 276 QSSLVWTTSPDEAKRLL-KLPKENFVDALNMALWDEDKKDSFAVRAGqvaqdlintvspegTSFRQLPptftdiedesra 354
Cdd:PRK07045 220 ATRLVVSFPADEMQGYLaDTTRTKLLARLNEFVGDESADAMAAIGAG--------------TAFPLIP------------ 273

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|...
gi 919034376 355 afpLSLVHASHYVKPRLALIGDAAHRVHPLAGQGVNLGFGDVTCLRDVLVQCL 407
Cdd:PRK07045 274 ---LGRMNLDRYHKRNVVLLGDAAHSIHPITGQGMNLAIEDAGELGACLDLHL 323
PRK07236 PRK07236
hypothetical protein; Provisional
 190-406 4.43e-07

hypothetical protein; Provisional


Pssm-ID: 235980 [Multi-domain]  Cd Length: 386  Bit Score: 51.85  E-value: 4.43e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 919034376 190 QDGVQenlwIKVHLPDGETFQTKLLIGADGFNSLVRKQ--ANIHTLQWDYEQW-GLVSTLHFAEPTenvvaWQRFLPTGP 266
Cdd:PRK07236 126 QDGDR----VTARFADGRRETADLLVGADGGRSTVRAQllPDVRPTYAGYVAWrGLVDEAALPPEA-----RAALRDRFT 196

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 919034376 267 VAVLPLSETQSSLVwttsPDE------AKRLLklpkeNFV--------DALNMALWDED-KKDSFAVRAGQVAQDLINTV 331
Cdd:PRK07236 197 FQLGPGSHILGYPV----PGEdgstepGKRRY-----NWVwyrnapagEELDELLTDRDgTRRPFSVPPGALRDDVLAEL 267

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 919034376 332 spEGTSFRQLPPTFTDIEDESRAAF--PLSLVHASHYVKPRLALIGDAAHRVHPLAGQGVNLGFGDVTCLRDVLVQC 406
Cdd:PRK07236 268 --RDDAAELLAPVFAELVEATAQPFvqAIFDLEVPRMAFGRVALLGDAAFVARPHTAAGVAKAAADAVALAEALAAA 342
PRK08244 PRK08244
monooxygenase;
188-395 8.11e-07

monooxygenase;


Pssm-ID: 236199 [Multi-domain]  Cd Length: 493  Bit Score: 51.28  E-value: 8.11e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 919034376 188 QIQDGVQenlwIKVHLPDGE-TFQTKLLIGADGFNSLVRKQANIHTLQWDYEQWGLVSTLHFAEPTENVVAwQRFLPTGP 266
Cdd:PRK08244 128 QDGDGVE----VVVRGPDGLrTLTSSYVVGADGAGSIVRKQAGIAFPGTDATFTAMLGDVVLKDPPPSSVL-SLCTREGG 202

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 919034376 267 VAVLPLSETQSSLVwTTSPDEAKRLLKLPkenfvdalnmalwdedkkdsfaVRAGQVAQDLINTVspeGTSFrqlppTFT 346
Cdd:PRK08244 203 VMIVPLSGGIYRVL-IIDPERPQVPKDEP----------------------VTLEELKTSLIRIC---GTDF-----GLN 251

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*....
gi 919034376 347 DIEDESRaaFPLSLVHASHYVKPRLALIGDAAHRVHPLAGQGVNLGFGD 395
Cdd:PRK08244 252 DPVWMSR--FGNATRQAERYRSGRIFLAGDAAHIHFPAGGQGLNVGLQD 298
PRK06753 PRK06753
hypothetical protein; Provisional
 194-409 9.23e-07

hypothetical protein; Provisional


Pssm-ID: 168661 [Multi-domain]  Cd Length: 373  Bit Score: 50.84  E-value: 9.23e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 919034376 194 QENLWIKVHLPDGETFQTKLLIGADGFNSLVRKQANIHT--LQWDYEQW-GLVSTLHFAEPTENVVAWQrflPTGPVAVL 270
Cdd:PRK06753 124 NETDKVTIHFADGESEAFDLCIGADGIHSKVRQSVNADSkvRYQGYTCFrGLIDDIDLKLPDCAKEYWG---TKGRFGIV 200

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 919034376 271 PLSETQssLVWTTSPDeakrllklPKENfvDALNMALWDEDKKDSFAVRAGQVAQDLINTvSPEGTSFRqlpptftDIED 350
Cdd:PRK06753 201 PLLNNQ--AYWFITIN--------AKER--DPKYSSFGKPHLQAYFNHYPNEVREILDKQ-SETGILHH-------DIYD 260

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 919034376 351 ESraafPLslvhaSHYVKPRLALIGDAAHRVHPLAGQGVNLGFGDVTClrdvLVQCLCN 409
Cdd:PRK06753 261 LK----PL-----KSFVYGRIVLLGDAAHATTPNMGQGAGQAMEDAIV----LANCLNA 306
PRK06185 PRK06185
FAD-dependent oxidoreductase;
368-458 7.97e-06

FAD-dependent oxidoreductase;


Pssm-ID: 235729 [Multi-domain]  Cd Length: 407  Bit Score: 47.93  E-value: 7.97e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 919034376 368 KPRLALIGDAAHRVHPLAGQGVNLGFGDVTCLRDVLVQCLCNGGdlGSLSHLLQYETSR----------QRKVLPvMFAM 437
Cdd:PRK06185 283 RPGLLCIGDAAHAMSPVGGVGINLAIQDAVAAANILAEPLRRGR--VSDRDLAAVQRRRefptrvtqalQRRIQR-RLLA 359

                         90       100
                 ....*....|....*....|.
gi 919034376 438 DGLKRlyGTDFPPVVVLRTLG 458
Cdd:PRK06185 360 PALAG--RGPLGPPLLLRLLN 378
PLN02985 PLN02985
squalene monooxygenase
 37-421 1.91e-05

squalene monooxygenase


Pssm-ID: 178566 [Multi-domain]  Cd Length: 514  Bit Score: 47.20  E-value: 1.91e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 919034376  37 RKDDNSqlfDVVISGGGMVGAAMACALGHanvfEDKKILLLEaspqKDFKLPEKYGNRVcaLSPATKKLLSGFGAWEEIC 116
Cdd:PLN02985  39 RKDGAT---DVIIVGAGVGGSALAYALAK----DGRRVHVIE----RDLREPERMMGEF--MQPGGRFMLSKLGLEDCLE 105

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 919034376 117 NMRYQPVKRMQVWDACSDAFITLNHDDMT---DDVAYIVENDVILaaimkqfDKIKHNVTVMYNSKAEMYTFPSQIQD-G 192
Cdd:PLN02985 106 GIDAQKATGMAVYKDGKEAVAPFPVDNNNfpyEPSARSFHNGRFV-------QRLRQKASSLPNVRLEEGTVKSLIEEkG 178

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 919034376 193 VQENLWIKVHLPDGETFQTKLLIGADGFNSLVRKQANIHTLQWDYEQWGLVSTLHFAEPTENVvawqrflptgpvaVLPL 272
Cdd:PLN02985 179 VIKGVTYKNSAGEETTALAPLTVVCDGCYSNLRRSLNDNNAEVLSYQVGYISKNCRLEEPEKL-------------HLIM 245

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 919034376 273 SETQSSLVWTTSPDEAKRLLKLPKENFVDALNmalwdedkkdsfavraGQVAQDLINTVSPegtsfrQLPPTFTDI---- 348
Cdd:PLN02985 246 SKPSFTMLYQISSTDVRCVFEVLPDNIPSIAN----------------GEMSTFVKNTIAP------QVPPKLRKIflkg 303

                        330       340       350       360       370       380       390
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 919034376 349 --EDESRAAFPLSLVHASHYVKPRLALIGDAAHRVHPLAGQGVNLGFGDVTCLRDvLVQCLCNGGDLGSLSHLLQ 421
Cdd:PLN02985 304 idEGAHIKVVPTKRMSATLSDKKGVIVLGDAFNMRHPAIASGMMVLLSDILILRR-LLQPLSNLGNANKVSEVIK 377
PTZ00367 PTZ00367
squalene epoxidase; Provisional
 45-405 1.57e-04

squalene epoxidase; Provisional


Pssm-ID: 240384 [Multi-domain]  Cd Length: 567  Bit Score: 44.07  E-value: 1.57e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 919034376  45 FDVVISGGGMVGAAMACALGHANvfedKKILLLEASPqkdFKLPekygNRVCA--LSP----ATKKLlsGFGAWEEICNM 118
Cdd:PTZ00367  34 YDVIIVGGSIAGPVLAKALSKQG----RKVLMLERDL---FSKP----DRIVGelLQPggvnALKEL--GMEECAEGIGM 100

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 919034376 119 R---YQPVK----------------------------RMQVWDACSDAFITLNHddmtdDVAYIVENDVILAAIMKqfdK 167
Cdd:PTZ00367 101 PcfgYVVFDhkgkqvklpygagasgvsfhfgdfvqnlRSHVFHNCQDNVTMLEG-----TVNSLLEEGPGFSERAY---G 172

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 919034376 168 IKHNVTVMYNSKAEMYTFPSQIQDGVQENLWIKVHLPdgetfqtkLLIGADGFNSLVRKQANIHTLQWDYEQW--GLV-S 244
Cdd:PTZ00367 173 VEYTEAEKYDVPENPFREDPPSANPSATTVRKVATAP--------LVVMCDGGMSKFKSRYQHYTPASENHSHfvGLVlK 244

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 919034376 245 TLHFAEPTENVVAwqrFLPTGPVavlplsetqssLVWTTSPDEAKRLLKLPKENFVDALNMALW---------DEDKKDS 315
Cdd:PTZ00367 245 NVRLPKEQHGTVF---LGKTGPI-----------LSYRLDDNELRVLVDYNKPTLPSLEEQSEWliedvaphlPENMRES 310

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 919034376 316 FaVRAGQvaqdliNTVSPEGTSFRQLPPTFTDIEDesraafplslvhashYVkprlaLIGDAAHRVHPLAGQGVNLGFGD 395
Cdd:PTZ00367 311 F-IRASK------DTKRIRSMPNARYPPAFPSIKG---------------YV-----GIGDHANQRHPLTGGGMTCCFSD 363

                        410
                 ....*....|
gi 919034376 396 VTCLRDVLVQ 405
Cdd:PTZ00367 364 CIRLAKSLTG 373
mhpA PRK06183
bifunctional 3-(3-hydroxy-phenyl)propionate/3-hydroxycinnamic acid hydroxylase;
363-399 1.47e-03

bifunctional 3-(3-hydroxy-phenyl)propionate/3-hydroxycinnamic acid hydroxylase;


Pssm-ID: 235727 [Multi-domain]  Cd Length: 500  Bit Score: 41.05  E-value: 1.47e-03
                         10        20        30
                 ....*....|....*....|....*....|....*..
gi 919034376 363 ASHYVKPRLALIGDAAHRVHPLAGQGVNLGFGDVTCL 399
Cdd:PRK06183 280 ADRWRSGRVLLAGDAAHLMPPFAGQGMNSGIRDAANL 316
SE pfam08491
Squalene epoxidase; This domain is found in squalene epoxidase (SE) and related proteins which ...
 321-403 1.54e-03

Squalene epoxidase; This domain is found in squalene epoxidase (SE) and related proteins which are found in taxonomically diverse groups of eukaryotes and also in bacteria. SE was first cloned from Saccharomyces cerevisiae where it was named ERG1. It contains a putative FAD binding site and is a key enzyme in the sterol biosynthetic pathway. Putative transmembrane regions are found to the protein's C-terminus.


Pssm-ID: 400679  Cd Length: 276  Bit Score: 40.39  E-value: 1.54e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 919034376  321 GQVAQDLINTVSPegtsfrQLP----PTFTDIEDESR-AAFPLSLVHASHYVKPRLALIGDAAHRVHPLAGQGVNLGFGD 395
Cdd:pfam08491  83 GELKEYLKKSVAP------QIPkelrPSFLAALEEGKiRSMPNSFLPASKNRKKGLILLGDALNMRHPLTGGGMTVGLND 156


                  ....*...
gi 919034376  396 VTCLRDVL 403
Cdd:pfam08491 157 IVLLRKLL 164
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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