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NADH-plastoquinone oxidoreductase subunit I (plastid) [Trillium tschonoskii]

Protein Classification

NAD(P)H-quinone oxidoreductase subunit I( domain architecture ID 11413996)

NAD(P)H-quinone oxidoreductase subunit I is a component of NDH, which shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ndhI CHL00014
NADH dehydrogenase subunit I
 4-170 3.19e-136

NADH dehydrogenase subunit I


:

Pssm-ID: 214334 [Multi-domain]  Cd Length: 167  Bit Score: 376.79  E-value: 3.19e-136
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 918020922   4 MVTRFMNYGQQTIRAARYIGQSFVITLSHTNRLPITIQYPYEKSITSERFRGRIHFEFDKCIACEVCVRVCPIDLPVVDW 83
Cdd:CHL00014   1 MVTGFMNYGQQTIRAARYIGQGFMITLSHANRLPVTIQYPYEKLITSERFRGRIHFEFDKCIACEVCVRVCPIDLPVVDW 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 918020922  84 RFERDIKKKQLLNYSIDFGICIFCGNCVEYCPTNCLSMTEEYELSTYDRHELNYNQIALGRLPMSVIGDYTIQTVMNSTQ 163
Cdd:CHL00014  81 KLETDIRKKRLLNYSIDFGVCIFCGNCVEYCPTNCLSMTEEYELSTYDRHELNYNQIALGRLPMSVIDDYTIRTISNSPQ 160


                 ....*..
gi 918020922 164 SKIYKEK 170
Cdd:CHL00014 161 IKIVEEK 167
 
Name Accession Description Interval E-value
ndhI CHL00014
NADH dehydrogenase subunit I
 4-170 3.19e-136

NADH dehydrogenase subunit I


Pssm-ID: 214334 [Multi-domain]  Cd Length: 167  Bit Score: 376.79  E-value: 3.19e-136
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 918020922   4 MVTRFMNYGQQTIRAARYIGQSFVITLSHTNRLPITIQYPYEKSITSERFRGRIHFEFDKCIACEVCVRVCPIDLPVVDW 83
Cdd:CHL00014   1 MVTGFMNYGQQTIRAARYIGQGFMITLSHANRLPVTIQYPYEKLITSERFRGRIHFEFDKCIACEVCVRVCPIDLPVVDW 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 918020922  84 RFERDIKKKQLLNYSIDFGICIFCGNCVEYCPTNCLSMTEEYELSTYDRHELNYNQIALGRLPMSVIGDYTIQTVMNSTQ 163
Cdd:CHL00014  81 KLETDIRKKRLLNYSIDFGVCIFCGNCVEYCPTNCLSMTEEYELSTYDRHELNYNQIALGRLPMSVIDDYTIRTISNSPQ 160


                 ....*..
gi 918020922 164 SKIYKEK 170
Cdd:CHL00014 161 IKIVEEK 167
ndhI TIGR00403
NADH-plastoquinone oxidoreductase subunit I protein; [Energy metabolism, Electron transport]
 1-179 5.73e-121

NADH-plastoquinone oxidoreductase subunit I protein; [Energy metabolism, Electron transport]


Pssm-ID: 129498 [Multi-domain]  Cd Length: 183  Bit Score: 339.20  E-value: 5.73e-121
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 918020922    1 MFSMVTRFMNYGQQTIRAARYIGQSFVITLSHTNRLPITIQYPYEKSITSERFRGRIHFEFDKCIACEVCVRVCPIDLPV 80
Cdd:TIGR00403   1 MFNILKGVGDYAQQSIQAARYIGQGFAVTLDHMNRLPITIQYPYEKLIPSERFRGRIHFEFDKCIACEVCVRVCPINLPV 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 918020922   81 VDWRFERDIKKKQLLNYSIDFGICIFCGNCVEYCPTNCLSMTEEYELSTYDRHELNYNQIALGRLPMSVIGDYTIQTVMN 160
Cdd:TIGR00403  81 VDWEFNKAIKKKQLKNYSIDFGVCIFCGNCVEYCPTNCLSMTEEYELSTYDRHELNYDQIALGRLPISITEDPTITPIRN 160

                         170       180
                  ....*....|....*....|
gi 918020922  161 STQS-KIYKEKSLDSRTITN 179
Cdd:TIGR00403 161 LTYLpKGVIEPHKGSRRITQ 180
NuoI COG1143
Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) [Energy ...
 62-134 2.17e-18

Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) [Energy production and conversion]; Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440758 [Multi-domain]  Cd Length: 66  Bit Score: 74.78  E-value: 2.17e-18
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 918020922  62 DKCIACEVCVRVCPIDLPVVDWRFERDIkkkqllnYSIDFGICIFCGNCVEYCPTNCLSMTeEYELSTYDRHE 134
Cdd:COG1143    2 DKCIGCGLCVRVCPVDAITIEDGEPGKV-------YVIDPDKCIGCGLCVEVCPTGAISMT-PFELAVEDREE 66
MtMvhB_like cd10549
Uncharacterized polyferredoxin-like protein; This family contains uncharacterized ...
 59-126 2.86e-13

Uncharacterized polyferredoxin-like protein; This family contains uncharacterized polyferredoxin protein similar to Methanobacterium thermoautotrophicum MvhB. The mvhB is a gene of the methylviologen-reducing hydrogenase operon. It is predicted to contain 12 [4Fe-4S] clusters, and was therefore suggested to be a polyferredoxin. As a subfamily of the beta subunit of the DMSO Reductase (DMSOR) family, it is predicted to function as electron carrier in the reducing reaction.


Pssm-ID: 319871 [Multi-domain]  Cd Length: 128  Bit Score: 63.18  E-value: 2.86e-13
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 918020922  59 FEFDKCIACEVCVRVCPID-LPVVDWRFERDIKKKqllNYSIDFGICIFCGNCVEYCPTNCLSMTEEYE 126
Cdd:cd10549   37 IDEDKCVFCGACVEVCPTGaIELTPEGKEYVPKEK---EAEIDEEKCIGCGLCVKVCPVDAITLEDELE 102
Fer4_7 pfam12838
4Fe-4S dicluster domain; Superfamily includes proteins containing domains which bind to ...
 64-118 6.85e-09

4Fe-4S dicluster domain; Superfamily includes proteins containing domains which bind to iron-sulfur clusters. Members include bacterial ferredoxins, various dehydrogenases, and various reductases. Structure of the domain is an alpha-antiparallel beta sandwich. Domain contains two 4Fe4S clusters.


Pssm-ID: 463724 [Multi-domain]  Cd Length: 51  Bit Score: 49.83  E-value: 6.85e-09
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 918020922   64 CIACEVCVRVCPIDLPVVDWRFERDIKKKqllnYSIDFGICIFCGNCVEYCPTNC 118
Cdd:pfam12838   1 CIGCGACVAACPVGAITLDEVGEKKGTKT----VVIDPERCVGCGACVAVCPTGA 51
 
Name Accession Description Interval E-value
ndhI CHL00014
NADH dehydrogenase subunit I
 4-170 3.19e-136

NADH dehydrogenase subunit I


Pssm-ID: 214334 [Multi-domain]  Cd Length: 167  Bit Score: 376.79  E-value: 3.19e-136
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 918020922   4 MVTRFMNYGQQTIRAARYIGQSFVITLSHTNRLPITIQYPYEKSITSERFRGRIHFEFDKCIACEVCVRVCPIDLPVVDW 83
Cdd:CHL00014   1 MVTGFMNYGQQTIRAARYIGQGFMITLSHANRLPVTIQYPYEKLITSERFRGRIHFEFDKCIACEVCVRVCPIDLPVVDW 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 918020922  84 RFERDIKKKQLLNYSIDFGICIFCGNCVEYCPTNCLSMTEEYELSTYDRHELNYNQIALGRLPMSVIGDYTIQTVMNSTQ 163
Cdd:CHL00014  81 KLETDIRKKRLLNYSIDFGVCIFCGNCVEYCPTNCLSMTEEYELSTYDRHELNYNQIALGRLPMSVIDDYTIRTISNSPQ 160


                 ....*..
gi 918020922 164 SKIYKEK 170
Cdd:CHL00014 161 IKIVEEK 167
ndhI TIGR00403
NADH-plastoquinone oxidoreductase subunit I protein; [Energy metabolism, Electron transport]
 1-179 5.73e-121

NADH-plastoquinone oxidoreductase subunit I protein; [Energy metabolism, Electron transport]


Pssm-ID: 129498 [Multi-domain]  Cd Length: 183  Bit Score: 339.20  E-value: 5.73e-121
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 918020922    1 MFSMVTRFMNYGQQTIRAARYIGQSFVITLSHTNRLPITIQYPYEKSITSERFRGRIHFEFDKCIACEVCVRVCPIDLPV 80
Cdd:TIGR00403   1 MFNILKGVGDYAQQSIQAARYIGQGFAVTLDHMNRLPITIQYPYEKLIPSERFRGRIHFEFDKCIACEVCVRVCPINLPV 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 918020922   81 VDWRFERDIKKKQLLNYSIDFGICIFCGNCVEYCPTNCLSMTEEYELSTYDRHELNYNQIALGRLPMSVIGDYTIQTVMN 160
Cdd:TIGR00403  81 VDWEFNKAIKKKQLKNYSIDFGVCIFCGNCVEYCPTNCLSMTEEYELSTYDRHELNYDQIALGRLPISITEDPTITPIRN 160

                         170       180
                  ....*....|....*....|
gi 918020922  161 STQS-KIYKEKSLDSRTITN 179
Cdd:TIGR00403 161 LTYLpKGVIEPHKGSRRITQ 180
PRK05888 PRK05888
NADH-quinone oxidoreductase subunit NuoI;
21-149 5.78e-57

NADH-quinone oxidoreductase subunit NuoI;


Pssm-ID: 235637 [Multi-domain]  Cd Length: 164  Bit Score: 176.23  E-value: 5.78e-57
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 918020922  21 YIGQSFVITLSHTNRLPITIQYPYEKSITSERFRGRIHFEFD-----KCIACEVCVRVCPIDLPVVDWRfERDIKKKQLL 95
Cdd:PRK05888  12 ELLKGLGVTLKYFFKKKVTIQYPEEKLPLSPRFRGRHALRRDpngeeRCIACKLCAAICPADAITIEAA-EREDGRRRTT 90

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....
gi 918020922  96 NYSIDFGICIFCGNCVEYCPTNCLSMTEEYELSTYDRHELNYNQIALGRLPMSV 149
Cdd:PRK05888  91 RYDINFGRCIFCGFCEEACPTDAIVETPDFELATETREELIYDKEKLLANGDRV 144
NuoI TIGR01971
NADH-quinone oxidoreductase, chain I; This model represents the I subunit (one of 14: A->N) of ...
 25-142 8.82e-54

NADH-quinone oxidoreductase, chain I; This model represents the I subunit (one of 14: A->N) of the NADH-quinone oxidoreductase complex I which generally couples NADH and ubiquinone oxidation/reduction in bacteria and mammalian mitochondria, but may act on NADPH and/or plastoquinone in cyanobacteria and plant chloroplasts. This model excludes "I" subunits from the closely related F420H2 dehydrogenase and formate hydrogenlyase complexes. [Energy metabolism, Electron transport]


Pssm-ID: 273902 [Multi-domain]  Cd Length: 122  Bit Score: 166.82  E-value: 8.82e-54
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 918020922   25 SFVITLSHTNRLPITIQYPYEKSITSERFRGRIHFEF-----DKCIACEVCVRVCP-IDLPVVDWrfERDIKKKQLLNYS 98
Cdd:TIGR01971   1 GLGLTLKYFFSKPVTVQYPEEKLYLPPRFRGRIVLTRdpngeEKCIGCTLCAAVCPaDAIRVVPA--EGEDGKRRLKFYE 78

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....
gi 918020922   99 IDFGICIFCGNCVEYCPTNCLSMTEEYELSTYDRHELNYNQIAL 142
Cdd:TIGR01971  79 INFGRCIFCGLCEEACPTDAIVLTPEFELATYTRSDLVYGKEDL 122
PRK12387 PRK12387
formate hydrogenlyase complex iron-sulfur subunit; Provisional
 37-135 4.81e-21

formate hydrogenlyase complex iron-sulfur subunit; Provisional


Pssm-ID: 183492 [Multi-domain]  Cd Length: 180  Bit Score: 85.08  E-value: 4.81e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 918020922  37 PITIQYPYEKSITSERFRGRIHFEFDKCIACEVCVRVCPIDLPVVDWRFERDIKKkqllnYSIDFGICIFCGNCVEYCPT 116
Cdd:PRK12387  13 TATSSYPLEPIAVDKNFRGKPEYNPQQCIGCAACVNACPSNALTVETDLATGELA-----WEFNLGRCIFCGRCEEVCPT 87

                         90
                 ....*....|....*....
gi 918020922 117 NCLSMTEEYELSTYDRHEL 135
Cdd:PRK12387  88 AAIKLSQEFELAVWKKEDL 106
PRK08348 PRK08348
NADH-plastoquinone oxidoreductase subunit; Provisional
 33-134 5.65e-21

NADH-plastoquinone oxidoreductase subunit; Provisional


Pssm-ID: 181399 [Multi-domain]  Cd Length: 120  Bit Score: 82.96  E-value: 5.65e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 918020922  33 TNRLPITIQYPyeksiTSERFRGRIHFEFDKCIACEVCVRVCPIDLPVvdwrFERDIKKKQLLNysidfGICIFCGNCVE 112
Cdd:PRK08348  18 TNLFPATEPVP-----VPEDFRGKILYDVDKCVGCRMCVTVCPAGVFV----YLPEIRKVALWT-----GRCVFCGQCVD 83

                         90       100
                 ....*....|....*....|..
gi 918020922 113 YCPTNCLSMTEEYELSTYDRHE 134
Cdd:PRK08348  84 VCPTGALQMSDDFLLASYDRFD 105
NuoI COG1143
Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) [Energy ...
 62-134 2.17e-18

Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) [Energy production and conversion]; Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440758 [Multi-domain]  Cd Length: 66  Bit Score: 74.78  E-value: 2.17e-18
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 918020922  62 DKCIACEVCVRVCPIDLPVVDWRFERDIkkkqllnYSIDFGICIFCGNCVEYCPTNCLSMTeEYELSTYDRHE 134
Cdd:COG1143    2 DKCIGCGLCVRVCPVDAITIEDGEPGKV-------YVIDPDKCIGCGLCVEVCPTGAISMT-PFELAVEDREE 66
PRK13984 PRK13984
putative oxidoreductase; Provisional
 35-125 5.96e-17

putative oxidoreductase; Provisional


Pssm-ID: 172486 [Multi-domain]  Cd Length: 604  Bit Score: 77.50  E-value: 5.96e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 918020922  35 RLPITIQYPYEKSITSERFRGRIHFEFDKCIACEVCVRVCPID----LPVVDWRFERDIKKKQLlnySIDFGICIFCGNC 110
Cdd:PRK13984  18 RKPVTIKVPNVKREAAERYRGFHINDWEKCIGCGTCSKICPTDaitmVEVPDLPQEYGKKPQRP---VIDYGRCSFCALC 94

                         90
                 ....*....|....*
gi 918020922 111 VEYCPTNCLSMTEEY 125
Cdd:PRK13984  95 VDICTTGSLKMTREY 109
MtMvhB_like cd10549
Uncharacterized polyferredoxin-like protein; This family contains uncharacterized ...
 59-126 2.86e-13

Uncharacterized polyferredoxin-like protein; This family contains uncharacterized polyferredoxin protein similar to Methanobacterium thermoautotrophicum MvhB. The mvhB is a gene of the methylviologen-reducing hydrogenase operon. It is predicted to contain 12 [4Fe-4S] clusters, and was therefore suggested to be a polyferredoxin. As a subfamily of the beta subunit of the DMSO Reductase (DMSOR) family, it is predicted to function as electron carrier in the reducing reaction.


Pssm-ID: 319871 [Multi-domain]  Cd Length: 128  Bit Score: 63.18  E-value: 2.86e-13
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 918020922  59 FEFDKCIACEVCVRVCPID-LPVVDWRFERDIKKKqllNYSIDFGICIFCGNCVEYCPTNCLSMTEEYE 126
Cdd:cd10549   37 IDEDKCVFCGACVEVCPTGaIELTPEGKEYVPKEK---EAEIDEEKCIGCGLCVKVCPVDAITLEDELE 102
PRK08222 PRK08222
hydrogenase 4 subunit H; Validated
 39-135 9.77e-13

hydrogenase 4 subunit H; Validated


Pssm-ID: 181301 [Multi-domain]  Cd Length: 181  Bit Score: 63.23  E-value: 9.77e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 918020922  39 TIQYPYEKSITSERFRGRIHFEFDKCIACEVCVRVCPIDLPVVDWRFERDIKKKQLLnysidFGICIFCGNCVEYCPTNC 118
Cdd:PRK08222  15 TVKYPFAPLEVSPGFRGKPDLMPSQCIACGACTCACPANALTIQTDDQQNSRTWQLY-----LGRCIYCGRCEEVCPTRA 89

                         90
                 ....*....|....*..
gi 918020922 119 LSMTEEYELSTYDRHEL 135
Cdd:PRK08222  90 IQLTNNFELTVTNKADL 106
MtMvhB_like cd10549
Uncharacterized polyferredoxin-like protein; This family contains uncharacterized ...
 62-139 1.12e-12

Uncharacterized polyferredoxin-like protein; This family contains uncharacterized polyferredoxin protein similar to Methanobacterium thermoautotrophicum MvhB. The mvhB is a gene of the methylviologen-reducing hydrogenase operon. It is predicted to contain 12 [4Fe-4S] clusters, and was therefore suggested to be a polyferredoxin. As a subfamily of the beta subunit of the DMSO Reductase (DMSOR) family, it is predicted to function as electron carrier in the reducing reaction.


Pssm-ID: 319871 [Multi-domain]  Cd Length: 128  Bit Score: 61.64  E-value: 1.12e-12
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 918020922  62 DKCIACEVCVRVCPID-LPVVDwrferdiKKKQLLNYSIDFGICIFCGNCVEYCPTNCLSMTEEYELSTYDRHELNYNQ 139
Cdd:cd10549    6 EKCIGCGICVKACPTDaIELGP-------NGAIARGPEIDEDKCVFCGACVEVCPTGAIELTPEGKEYVPKEKEAEIDE 77
COG2768 COG2768
Uncharacterized Fe-S cluster protein [Function unknown];
62-126 1.16e-11

Uncharacterized Fe-S cluster protein [Function unknown];


Pssm-ID: 442050 [Multi-domain]  Cd Length: 74  Bit Score: 57.43  E-value: 1.16e-11
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 918020922  62 DKCIACEVCVRVCPIDLPVVDwrferdiKKKqllnYSIDFGICIFCGNCVEYCPTNCLSMTEEYE 126
Cdd:COG2768   11 EKCIGCGACVKVCPVGAISIE-------DGK----AVIDPEKCIGCGACIEVCPVGAIKIEWEED 64
MtMvhB_like cd10549
Uncharacterized polyferredoxin-like protein; This family contains uncharacterized ...
 62-122 4.53e-11

Uncharacterized polyferredoxin-like protein; This family contains uncharacterized polyferredoxin protein similar to Methanobacterium thermoautotrophicum MvhB. The mvhB is a gene of the methylviologen-reducing hydrogenase operon. It is predicted to contain 12 [4Fe-4S] clusters, and was therefore suggested to be a polyferredoxin. As a subfamily of the beta subunit of the DMSO Reductase (DMSOR) family, it is predicted to function as electron carrier in the reducing reaction.


Pssm-ID: 319871 [Multi-domain]  Cd Length: 128  Bit Score: 57.41  E-value: 4.53e-11
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 918020922  62 DKCIACEVCVRVCPIDLpvvdwrferdIKKKQLLNYSIDFGICIFCGNCVEYCPTNCLSMT 122
Cdd:cd10549   78 EKCIGCGLCVKVCPVDA----------ITLEDELEIVIDKEKCIGCGICAEVCPVNAIKLV 128
PreA COG1146
NAD-dependent dihydropyrimidine dehydrogenase, PreA subunit [Nucleotide transport and ...
 55-126 2.67e-10

NAD-dependent dihydropyrimidine dehydrogenase, PreA subunit [Nucleotide transport and metabolism];


Pssm-ID: 440761 [Multi-domain]  Cd Length: 67  Bit Score: 53.94  E-value: 2.67e-10
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 918020922  55 GRIHFEFDKCIACEVCVRVCPIDLpvvdwrFERDIKKKQLLNYSIDFgiCIFCGNCVEYCPTNCLSMTEEYE 126
Cdd:COG1146    1 MMPVIDTDKCIGCGACVEVCPVDV------LELDEEGKKALVINPEE--CIGCGACELVCPVGAITVEDDEP 64
DMSOR_beta_like cd16370
uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the ...
 55-123 5.45e-10

uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the small beta iron-sulfur (FeS) subunit of the DMSO Reductase (DMSOR) family. Members of this family also contain a large, periplasmic molybdenum-containing alpha subunit and may have a small gamma subunit as well. Examples of heterodimeric members with alpha and beta subunits include arsenite oxidase, and tungsten-containing formate dehydrogenase (FDH-T) while heterotrimeric members containing alpha, beta, and gamma subunits include formate dehydrogenase-N (FDH-N), and nitrate reductase (NarGHI). The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.


Pssm-ID: 319892 [Multi-domain]  Cd Length: 131  Bit Score: 54.59  E-value: 5.45e-10
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 918020922  55 GRIHFEFDKCIACEVCVRVCPIDlpVVDWRFErdikkkqlLNYSIdfgICIFCGNCVEYCPTNCLSMTE 123
Cdd:cd16370   76 GGVVLDKEKCIGCGNCVKACIVG--AIFWDEE--------TNKPI---ICIHCGYCARYCPHDVLAMEE 131
NapF COG1145
Ferredoxin [Energy production and conversion];
62-124 5.83e-10

Ferredoxin [Energy production and conversion];


Pssm-ID: 440760 [Multi-domain]  Cd Length: 238  Bit Score: 56.65  E-value: 5.83e-10
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 918020922  62 DKCIACEVCVRVCPIDLpvvdwrFERDIKKKQllnYSIDFGICIFCGNCVEYCPTNCLSMTEE 124
Cdd:COG1145  182 EKCIGCGLCVKVCPTGA------IRLKDGKPQ---IVVDPDKCIGCGACVKVCPVGAISLEPK 235
PorD COG1144
Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, delta ...
 56-126 7.61e-10

Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, delta subunit [Energy production and conversion]; Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, delta subunit is part of the Pathway/BioSystem: Pyruvate oxidation


Pssm-ID: 440759 [Multi-domain]  Cd Length: 84  Bit Score: 53.13  E-value: 7.61e-10
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 918020922  56 RIHFEFDKCIACEVCVRVCPIDlpVVDWRferDIKKkqllnYSIDFGICIFCGNCVEYCPTNCLSMTEEYE 126
Cdd:COG1144   24 RPVVDEDKCIGCGLCWIVCPDG--AIRVD---DGKY-----YGIDYDYCKGCGICAEVCPVKAIEMVPEEK 84
NapH COG0348
Polyferredoxin NapH [Energy production and conversion];
56-122 5.37e-09

Polyferredoxin NapH [Energy production and conversion];


Pssm-ID: 440117 [Multi-domain]  Cd Length: 263  Bit Score: 53.91  E-value: 5.37e-09
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 918020922  56 RIHFEFDKCIACEVCVRVCPIDLpvvdwrferDIKKKQLLNYSidfgiCIFCGNCVEYCPTNCLSMT 122
Cdd:COG0348  204 RVRYDRGDCIDCGLCVKVCPMGI---------DIRKGEINQSE-----CINCGRCIDACPKDAIRFS 256
Fer4_7 pfam12838
4Fe-4S dicluster domain; Superfamily includes proteins containing domains which bind to ...
 64-118 6.85e-09

4Fe-4S dicluster domain; Superfamily includes proteins containing domains which bind to iron-sulfur clusters. Members include bacterial ferredoxins, various dehydrogenases, and various reductases. Structure of the domain is an alpha-antiparallel beta sandwich. Domain contains two 4Fe4S clusters.


Pssm-ID: 463724 [Multi-domain]  Cd Length: 51  Bit Score: 49.83  E-value: 6.85e-09
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 918020922   64 CIACEVCVRVCPIDLPVVDWRFERDIKKKqllnYSIDFGICIFCGNCVEYCPTNC 118
Cdd:pfam12838   1 CIGCGACVAACPVGAITLDEVGEKKGTKT----VVIDPERCVGCGACVAVCPTGA 51
COG1149 COG1149
MinD superfamily P-loop ATPase, contains an inserted ferredoxin domain [General function ...
 54-123 9.63e-09

MinD superfamily P-loop ATPase, contains an inserted ferredoxin domain [General function prediction only];


Pssm-ID: 440763 [Multi-domain]  Cd Length: 68  Bit Score: 49.73  E-value: 9.63e-09
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 918020922  54 RGRIHFEFDKCIACEVCVRVCPIDLpvvdwrferdIKKKQLLNYSIDFGICIFCGNCVEYCPTNCLSMTE 123
Cdd:COG1149    3 RKIPVIDEEKCIGCGLCVEVCPEGA----------IKLDDGGAPVVDPDLCTGCGACVGVCPTGAITLEE 62
DsrA COG2221
Dissimilatory sulfite reductase (desulfoviridin), alpha and beta subunits [Inorganic ion ...
 56-120 1.31e-08

Dissimilatory sulfite reductase (desulfoviridin), alpha and beta subunits [Inorganic ion transport and metabolism];


Pssm-ID: 441823 [Multi-domain]  Cd Length: 69  Bit Score: 49.28  E-value: 1.31e-08
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 918020922  56 RIHFEFDKCIACEVCVRVCPID-LPVVDWRFERDIKKkqllnysidfgiCIFCGNCVEYCPTNCLS 120
Cdd:COG2221    9 PPKIDEEKCIGCGLCVAVCPTGaISLDDGKLVIDEEK------------CIGCGACIRVCPTGAIK 62
Nar1 COG4624
Iron only hydrogenase large subunit, C-terminal domain [Energy production and conversion];
46-120 1.63e-08

Iron only hydrogenase large subunit, C-terminal domain [Energy production and conversion];


Pssm-ID: 443663 [Multi-domain]  Cd Length: 450  Bit Score: 52.72  E-value: 1.63e-08
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 918020922  46 KSITSERFRGRIHFEFDKCIACEVCVRVCPIDLPVVDWRFErdikkkqllnySIDFGICIFCGNCVEYCPTNCLS 120
Cdd:COG4624   75 GIIIIDKRGPSIIRDKEKCKNCYPCVRACPVKAIKVDDGKA-----------EIDEEKCISCGQCVAVCPFGAIT 138
IorA COG4231
TPP-dependent indolepyruvate ferredoxin oxidoreductase, alpha subunit [Energy production and ...
 62-124 6.06e-08

TPP-dependent indolepyruvate ferredoxin oxidoreductase, alpha subunit [Energy production and conversion];


Pssm-ID: 443375 [Multi-domain]  Cd Length: 76  Bit Score: 47.73  E-value: 6.06e-08
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 918020922  62 DKCIACEVCVRVCPIDLpvvdwrFERDIKKkqllnYSIDFGICIFCGNCVEYCPTNCLSMTEE 124
Cdd:COG4231   22 DKCTGCGACVKVCPADA------IEEGDGK-----AVIDPDLCIGCGSCVQVCPVDAIKLEKR 73
DMSOR_beta_like cd10550
uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the ...
 45-120 6.15e-08

uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the small beta iron-sulfur (FeS) subunit of the DMSO Reductase (DMSOR) family. Members of this family also contain a large, periplasmic molybdenum-containing alpha subunit and may have a small gamma subunit as well. Examples of heterodimeric members with alpha and beta subunits include arsenite oxidase, and tungsten-containing formate dehydrogenase (FDH-T) while heterotrimeric members containing alpha, beta, and gamma subunits include formate dehydrogenase-N (FDH-N), and nitrate reductase (NarGHI). The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.


Pssm-ID: 319872 [Multi-domain]  Cd Length: 130  Bit Score: 49.11  E-value: 6.15e-08
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 918020922  45 EKSITSERFRGRIHFEFDKCIACEVCVRVCPIDLPVVDWRFERDIKkkqllnysidfgiCIFCGN---CVEYCPTNCLS 120
Cdd:cd10550   63 VGAISRDEETGAVVVDEDKCIGCGMCVEACPFGAIRVDPETGKAIK-------------CDLCGGdpaCVKVCPTGALE 128
HycB COG1142
Fe-S-cluster-containing hydrogenase component 2 [Energy production and conversion];
51-124 8.81e-08

Fe-S-cluster-containing hydrogenase component 2 [Energy production and conversion];


Pssm-ID: 440757 [Multi-domain]  Cd Length: 138  Bit Score: 48.89  E-value: 8.81e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 918020922  51 ERFRGRIHFEFDKCIACEVCVRVCPIDLPVVDWRFERDIKKKqllnysidfgiCIFCGN------CVEYCPTNCLSMTEE 124
Cdd:COG1142   70 TRDDGAVVVDEEKCIGCGLCVLACPFGAITMVGEKSRAVAVK-----------CDLCGGreggpaCVEACPTGALRLVDV 138
FDH-N cd10558
The beta FeS subunit of formate dehydrogenase-N (FDH-N); This subfamily contains beta FeS ...
 55-133 9.75e-08

The beta FeS subunit of formate dehydrogenase-N (FDH-N); This subfamily contains beta FeS subunit of formate dehydrogenase-N (FDH-N), a member of the DMSO reductase family. FDH-N is involved in the major anaerobic respiratory pathway in the presence of nitrate, catalyzing the oxidation of formate to carbon dioxide at the expense of nitrate reduction to nitrite. Thus, FDH-N is a major component of nitrate respiration of Escherichia coli. This integral membrane enzyme forms a heterotrimer; the alpha-subunit (FDH-G) is the catalytic site of formate oxidation and membrane-associated, incorporating a selenocysteine (SeCys) residue and a [4Fe/4S] cluster in addition to two bis-MGD cofactors, the beta subunit (FDH-H) contains four [4Fe/4S] clusters which transfer the electrons from the alpha subunit to the gamma-subunit (FDH-I), a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups.


Pssm-ID: 319880 [Multi-domain]  Cd Length: 208  Bit Score: 49.69  E-value: 9.75e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 918020922  55 GRIHFEFDKCIACEVCVRVCPIDLPvvdwRFERDIKK--KqllnysidfgiCIFCGN---------CVEYCPTNCLSMTE 123
Cdd:cd10558   94 GIVDFQSDKCIGCGYCIKGCPFDIP----RISKDDNKmyK-----------CTLCSDrvsvglepaCVKTCPTGALHFGT 158

                         90
                 ....*....|
gi 918020922 124 EYELSTYDRH 133
Cdd:cd10558  159 KEDMLALAEK 168
DMSOR_beta-like cd04410
Beta subunit of the DMSO Reductase (DMSOR) family; This family consists of the small beta ...
 55-119 1.03e-07

Beta subunit of the DMSO Reductase (DMSOR) family; This family consists of the small beta iron-sulfur (FeS) subunit of the DMSO Reductase (DMSOR) family. Members of this family also contain a large, periplasmic molybdenum-containing alpha subunit and may have a small gamma subunit as well. Examples of heterodimeric members with alpha and beta subunits include arsenite oxidase, and tungsten-containing formate dehydrogenase (FDH-T) while heterotrimeric members containing alpha, beta, and gamma subunits include formate dehydrogenase-N (FDH-N), and nitrate reductase (NarGHI). The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.


Pssm-ID: 319870 [Multi-domain]  Cd Length: 136  Bit Score: 48.54  E-value: 1.03e-07
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 918020922  55 GRIHFEFDKCIACEVCVRVCPIDLPVVDWRFERDIKkkqllnysidfgiCIFCGN---------CVEYCPTNCL 119
Cdd:cd04410   73 GIVLIDEDKCIGCGSCVEACPYGAIVFDPEPGKAVK-------------CDLCGDrldeglepaCVKACPTGAL 133
Fer4_10 pfam13237
4Fe-4S dicluster domain; This family includes proteins containing domains which bind to ...
 56-115 2.21e-07

4Fe-4S dicluster domain; This family includes proteins containing domains which bind to iron-sulfur clusters. Members include bacterial ferredoxins, various dehydrogenases, and various reductases. The structure of the domain is an alpha-antiparallel beta sandwich.


Pssm-ID: 404174 [Multi-domain]  Cd Length: 56  Bit Score: 45.70  E-value: 2.21e-07
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 918020922   56 RIHFEFDKCIACEVCVRVCPIDLPVVDWRFERDIKKKQLLNYSidfgICIFCGNCVEYCP 115
Cdd:pfam13237   1 KVVIDPDKCIGCGRCTAACPAGLTRVGAIVERLEGEAVRIGVW----KCIGCGACVEACP 56
PRK09898 PRK09898
ferredoxin-like protein;
46-129 2.37e-07

ferredoxin-like protein;


Pssm-ID: 182135 [Multi-domain]  Cd Length: 208  Bit Score: 48.68  E-value: 2.37e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 918020922  46 KSITSERFRGRIHFEFDKCIACEVCVRVCPIDLPVVDwrfeRDIKKKqllnysidfGICIFCGNCVEYCPTNCLSMTEEY 125
Cdd:PRK09898 138 GAITWQQKEGCITVDHKRCIGCSACTTACPWMMATVN----TESKKS---------SKCVLCGECANACPTGALKIIEWK 204


                 ....
gi 918020922 126 ELST 129
Cdd:PRK09898 205 DITV 208
HdrA COG1148
Heterodisulfide reductase, subunit A (polyferredoxin) [Energy production and conversion];
58-121 6.30e-07

Heterodisulfide reductase, subunit A (polyferredoxin) [Energy production and conversion];


Pssm-ID: 440762 [Multi-domain]  Cd Length: 563  Bit Score: 48.32  E-value: 6.30e-07
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 918020922  58 HFEFDKCIACEVCVRVCPIDLPVVDwrferDIKKkqllnYSIDFGICIFCGNCVEYCPTNCLSM 121
Cdd:COG1148  492 EVDPEKCTGCGRCVEVCPYGAISID-----EKGV-----AEVNPALCKGCGTCAAACPSGAISL 545
PRK07118 PRK07118
Fe-S cluster domain-containing protein;
64-124 6.32e-07

Fe-S cluster domain-containing protein;


Pssm-ID: 235941 [Multi-domain]  Cd Length: 280  Bit Score: 48.01  E-value: 6.32e-07
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 918020922  64 CIACEVCVRVCPIDLpvvdwrferdIKKKQLLNYsIDFGICIFCGNCVEYCPTNCLSMTEE 124
Cdd:PRK07118 215 CIGCGKCVKACPAGA----------ITMENNLAV-IDQEKCTSCGKCVEKCPTKAIRILNK 264
PRK14028 PRK14028
pyruvate ferredoxin oxidoreductase subunit gamma/delta; Provisional
 63-124 1.38e-06

pyruvate ferredoxin oxidoreductase subunit gamma/delta; Provisional


Pssm-ID: 172522 [Multi-domain]  Cd Length: 312  Bit Score: 47.30  E-value: 1.38e-06
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 918020922  63 KCIACEVCVRVCPIDLPVVDWRFERDIKKKQLLNYSIDF--GICIFCGNCVEYCPTNCLSMTEE 124
Cdd:PRK14028 248 KCIMCRKCWLYCPDDAIIEAWREAEGPRGRKFRMKMIDFdyQYCKGCGVCAEVCPTGAIQMVRE 311
rnfB TIGR01944
electron transport complex, RnfABCDGE type, B subunit; The six subunit complex RnfABCDGE in ...
 62-124 2.74e-06

electron transport complex, RnfABCDGE type, B subunit; The six subunit complex RnfABCDGE in Rhodobacter capsulatus encodes an apparent NADH oxidoreductase responsible for electron transport to nitrogenase, necessary for nitrogen fixation. A closely related complex in E. coli, RsxABCDGE (Reducer of SoxR), reduces the 2Fe-2S-containing superoxide sensor SoxR, active as a transcription factor when oxidized. This family of putative NADH oxidoreductase complexes exists in many of the same species as the related NQR, a Na(+)-translocating NADH-quinone reductase, but is distinct. This model describes the B subunit. [Energy metabolism, Electron transport]


Pssm-ID: 273887 [Multi-domain]  Cd Length: 165  Bit Score: 45.17  E-value: 2.74e-06
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 918020922   62 DKCIACEVCVRVCPIDLPVVDWRFERDIKKKQllnysidfgiCIFCGNCVEYCPTNCLSMTEE 124
Cdd:TIGR01944 113 DNCIGCTKCIQACPVDAIVGAAKAMHTVIADE----------CTGCDLCVEPCPTDCIEMIPV 165
RnfB COG2878
Na+-translocating ferredoxin:NAD+ oxidoreductase RNF, RnfB subunit [Energy production and ...
 64-121 3.01e-06

Na+-translocating ferredoxin:NAD+ oxidoreductase RNF, RnfB subunit [Energy production and conversion]; Na+-translocating ferredoxin:NAD+ oxidoreductase RNF, RnfB subunit is part of the Pathway/BioSystem: Na+-translocating Fd:NADH oxidoreductase


Pssm-ID: 442125 [Multi-domain]  Cd Length: 254  Bit Score: 45.76  E-value: 3.01e-06
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 918020922  64 CIACEVCVRVCPID--------LPVVDwrferdiKKKqllnysidfgiCIFCGNCVEYCPTNCLSM 121
Cdd:COG2878  139 CIGCGDCIKACPFDaivgaakgMHTVD-------EDK-----------CTGCGLCVEACPVDCIEM 186
Fer4_9 pfam13187
4Fe-4S dicluster domain;
63-119 6.41e-06

4Fe-4S dicluster domain;


Pssm-ID: 463801 [Multi-domain]  Cd Length: 50  Bit Score: 41.77  E-value: 6.41e-06
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 918020922   63 KCIACEVCVRVCPIDLPVVDWRferdikkKQLLNYSIDFGICIFCGNCVEYCPTNCL 119
Cdd:pfam13187   1 KCTGCGACVAACPAGAIVPDLV-------GQTIRGDIAGLACIGCGACVDACPRGAI 50
SdhB/FrdB COG0479
Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit [Energy production and ...
 59-115 7.25e-06

Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit [Energy production and conversion]; Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit is part of the Pathway/BioSystem: TCA cycle


Pssm-ID: 440247 [Multi-domain]  Cd Length: 230  Bit Score: 44.74  E-value: 7.25e-06
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 918020922  59 FEFDKCIACEVCVRVCPidlpVVDW--------------RFE---RDIKKKQ-LLNYSIDFGI--CIFCGNCVEYCP 115
Cdd:COG0479  139 DDLAECILCGACVAACP----NVWAnpdflgpaalaqayRFAldpRDEETEErLEALEDEEGVwrCTTCGNCTEVCP 211
ACS_1 cd01916
Acetyl-CoA synthase (ACS), also known as acetyl-CoA decarbonylase, is found in acetogenic and ...
 60-123 1.91e-05

Acetyl-CoA synthase (ACS), also known as acetyl-CoA decarbonylase, is found in acetogenic and methanogenic organisms and is responsible for the synthesis and breakdown of acetyl-CoA. ACS forms a heterotetramer with carbon monoxide dehydrogenase (CODH) consisting of two ACS and two CODH subunits. CODH reduces carbon dioxide to carbon monoxide and ACS then synthesizes acetyl-CoA from carbon monoxide, CoA, and a methyl group donated by another protein (CoFeSP). ACS has three structural domains, an N-terminal rossman fold domain with a helical region at its N-terminus which interacts with CODH, and two alpha + beta fold domains. A Ni-Fe-S center referred to as the A-cluster is located in the C-terminal domain. A large cavity exists between the three domains which may bind CoA.


Pssm-ID: 238897 [Multi-domain]  Cd Length: 731  Bit Score: 43.94  E-value: 1.91e-05
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 918020922  60 EFDKCIACEVCVRVCPIDLPVVD---WRFERDIKKKQLLnysidFGICIFCGNCVEYCPTN--CLSMTE 123
Cdd:cd01916  363 LAAKCTDCGWCTRACPNSLRIKEameAAKEGDFSGLADL-----FDQCVGCGRCEQECPKEipIINMIE 426
vorD PRK09623
3-methyl-2-oxobutanoate dehydrogenase subunit delta;
62-124 2.07e-05

3-methyl-2-oxobutanoate dehydrogenase subunit delta;


Pssm-ID: 170016 [Multi-domain]  Cd Length: 105  Bit Score: 41.86  E-value: 2.07e-05
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 918020922  62 DKCIACEVCVRVCPidlpvvdwrfERDIKKKQLLNYSIDFGICIFCGNCVEYCPTNCLSMTEE 124
Cdd:PRK09623  51 SKCVKCYICWKFCP----------EPAIYIKEDGYVAIDYDYCKGCGICANECPTKAITMVKE 103
HybA COG0437
Fe-S-cluster-containing dehydrogenase component (DMSO reductase) [Energy production and ...
 55-119 2.59e-05

Fe-S-cluster-containing dehydrogenase component (DMSO reductase) [Energy production and conversion];


Pssm-ID: 440206 [Multi-domain]  Cd Length: 184  Bit Score: 42.63  E-value: 2.59e-05
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 918020922  55 GRIHFEFDKCIACEVCVRVCPIDLPvvdwRFERDIKK--KqllnysidfgiCIFCGN---------CVEYCPTNCL 119
Cdd:COG0437   83 GIVLVDYDKCIGCRYCVAACPYGAP----RFNPETGVveK-----------CTFCADrldegllpaCVEACPTGAL 143
porD PRK09625
pyruvate flavodoxin oxidoreductase subunit delta; Reviewed
 62-126 2.81e-05

pyruvate flavodoxin oxidoreductase subunit delta; Reviewed


Pssm-ID: 236596 [Multi-domain]  Cd Length: 133  Bit Score: 42.04  E-value: 2.81e-05
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 918020922  62 DKCIACEVCVRVCPiDLPVVDwrferdiKKKQLLnySIDFGICIFCGNCVEYCPTN--CLSMTEEYE 126
Cdd:PRK09625  59 EICINCFNCWVYCP-DAAILS-------RDKKLK--GVDYSHCKGCGVCVEVCPTNpkSLLMFEEQI 115
PRK08493 PRK08493
NADH-quinone oxidoreductase subunit G;
55-120 5.23e-05

NADH-quinone oxidoreductase subunit G;


Pssm-ID: 236277 [Multi-domain]  Cd Length: 819  Bit Score: 42.77  E-value: 5.23e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 918020922  55 GRIHFEFDKCIACEVCVRVC------------PIDLPVVDWRFERDIKKKQL-----LNYSI------DFGICIFCGNCV 111
Cdd:PRK08493 134 GKINYDPSLCIVCERCVTVCkdkigesalktvPRGLDAPDKSFKESMPKDAYavwskKQKSLigpvggETLDCSFCGECI 213


                 ....*....
gi 918020922 112 EYCPTNCLS 120
Cdd:PRK08493 214 AVCPVGALS 222
NapF_like cd10564
NapF, iron-sulfur subunit of periplasmic nitrate reductase; This family contains NapF protein, ...
 61-124 6.90e-05

NapF, iron-sulfur subunit of periplasmic nitrate reductase; This family contains NapF protein, the iron-sulfur subunit of periplasmic nitrate reductase. The periplasmic nitrate reductase NapABC of Escherichia coli likely functions during anaerobic growth in low-nitrate environments; napF operon expression is activated by cyclic AMP receptor protein (Crp). NapF is a subfamily of the beta subunit of DMSO reductase (DMSOR) family. DMSOR family members have a large, periplasmic molybdenum-containing alpha subunit as well as a small beta FeS subunit, and may also have a small gamma subunit. The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.


Pssm-ID: 319886 [Multi-domain]  Cd Length: 139  Bit Score: 40.69  E-value: 6.90e-05
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 918020922  61 FDKCIACEVCVRVCPID--------LPVVDwrferdikkkqllnysIDFGICIFCGNCVEYCPTNCLSMTEE 124
Cdd:cd10564   12 LDLCTRCGDCVEACPEGiivrgdggFPELD----------------FSRGECTFCGACAEACPEGALDPARE 67
Fer4_8 pfam13183
4Fe-4S dicluster domain; Superfamily includes proteins containing domains which bind to ...
 63-117 8.73e-05

4Fe-4S dicluster domain; Superfamily includes proteins containing domains which bind to iron-sulfur clusters. Members include bacterial ferredoxins, various dehydrogenases, and various reductases. Structure of the domain is an alpha-antiparallel beta sandwich. Domain contains two 4Fe4S clusters.


Pssm-ID: 433017 [Multi-domain]  Cd Length: 64  Bit Score: 38.83  E-value: 8.73e-05
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 918020922   63 KCIACEVCVRVCPIDL--------PVVDWRFERDIKKKQLLNYSIDFGICIFCGNCVEYCPTN 117
Cdd:pfam13183   1 RCIRCGACLAACPVYLvtggrfpgDPRGGAAALLGRLEALEGLAEGLWLCTLCGACTEVCPVG 63
DMSOR_beta_like cd16373
uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the ...
 55-116 1.20e-04

uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the small beta iron-sulfur (FeS) subunit of the DMSO Reductase (DMSOR) family. Members of this family also contain a large, periplasmic molybdenum-containing alpha subunit and may have a small gamma subunit as well. Examples of heterodimeric members with alpha and beta subunits include arsenite oxidase, and tungsten-containing formate dehydrogenase (FDH-T) while heterotrimeric members containing alpha, beta, and gamma subunits include formate dehydrogenase-N (FDH-N), and nitrate reductase (NarGHI). The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.


Pssm-ID: 319895 [Multi-domain]  Cd Length: 154  Bit Score: 40.32  E-value: 1.20e-04
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 918020922  55 GRIHFEFDKCIA------CEVCVRVCPIDLPVVDWRFERDIKKkqllnysIDFGICIFCGNCVEYCPT 116
Cdd:cd16373   84 GVAVIDKDRCLAwqggtdCGVCVEACPTEAIAIVLEDDVLRPV-------VDEDKCVGCGLCEYVCPV 144
porD PRK09624
pyruvate ferredoxin oxidoreductase subunit delta; Reviewed
 59-124 1.71e-04

pyruvate ferredoxin oxidoreductase subunit delta; Reviewed


Pssm-ID: 170017 [Multi-domain]  Cd Length: 105  Bit Score: 39.24  E-value: 1.71e-04
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 918020922  59 FEFDKCIACEVCVRVCPIDLPVVDWRferdikkkqllNYSI-DFGICIFCGNCVEYCPTNCLSMTEE 124
Cdd:PRK09624  48 FNRDKCVRCYLCYIYCPEPAIYLDEE-----------GYPVfDYDYCKGCGICANECPTKAIEMVRE 103
PRK13795 PRK13795
hypothetical protein; Provisional
 63-115 2.08e-04

hypothetical protein; Provisional


Pssm-ID: 237510 [Multi-domain]  Cd Length: 636  Bit Score: 40.75  E-value: 2.08e-04
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|...
gi 918020922  63 KCIACEVCVRVCPIDlpvvdwRFERDIKKKQLlnySIDFGICIFCGNCVEYCP 115
Cdd:PRK13795 582 ECVGCGVCVGACPTG------AIRIEEGKRKI---SVDEEKCIHCGKCTEVCP 625
napF TIGR00402
ferredoxin-type protein NapF; The gene codes for a ferredoxin-type cytosolic protein, NapF, of ...
 64-120 2.95e-04

ferredoxin-type protein NapF; The gene codes for a ferredoxin-type cytosolic protein, NapF, of the periplasmic nitrate reductase system, as in Escherichia coli. NapF interacts with the catalytic subunit, NapA, and may be an accessory protein for NapA maturation. [Energy metabolism, Electron transport]


Pssm-ID: 273060 [Multi-domain]  Cd Length: 101  Bit Score: 38.39  E-value: 2.95e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 918020922   64 CIACEVCVRVCPIDLpvvdwrferdIKKKQ--LLNYSIDFGICIFCGNCVEYCPTNCLS 120
Cdd:TIGR00402  36 CTRCGECASACENNI----------LQLGQqgQPTVEFDNAECDFCGKCAEACPTNAFH 84
psaC CHL00065
photosystem I subunit VII
 61-120 3.34e-04

photosystem I subunit VII


Pssm-ID: 177005 [Multi-domain]  Cd Length: 81  Bit Score: 37.82  E-value: 3.34e-04
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 918020922  61 FDKCIACEVCVRVCPID-LPVVDWrferDIKKKQLLNYSIDFGICIFCGNCVEYCPTNCLS 120
Cdd:CHL00065   8 YDTCIGCTQCVRACPTDvLEMIPW----DGCKAKQIASAPRTEDCVGCKRCESACPTDFLS 64
Fer4 pfam00037
4Fe-4S binding domain; Superfamily includes proteins containing domains which bind to ...
 97-120 3.53e-04

4Fe-4S binding domain; Superfamily includes proteins containing domains which bind to iron-sulfur clusters. Members include bacterial ferredoxins, various dehydrogenases, and various reductases. Structure of the domain is an alpha-antiparallel beta sandwich.


Pssm-ID: 459642 [Multi-domain]  Cd Length: 24  Bit Score: 36.46  E-value: 3.53e-04
                          10        20
                  ....*....|....*....|....
gi 918020922   97 YSIDFGICIFCGNCVEYCPTNCLS 120
Cdd:pfam00037   1 VVIDEEKCIGCGACVEVCPVGAIT 24
NapF COG1145
Ferredoxin [Energy production and conversion];
62-124 3.61e-04

Ferredoxin [Energy production and conversion];


Pssm-ID: 440760 [Multi-domain]  Cd Length: 238  Bit Score: 39.71  E-value: 3.61e-04
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 918020922  62 DKCIACEVCVRVCPIDLPVVDWRFE-RDIKKKQLLNYSIDFGICIFCGNCVEYCPTNCLSMTEE 124
Cdd:COG1145  141 EAGLAILGAAAPVDALAISGGKKIEeELKIAIKKAKAVIDAEKCIGCGLCVKVCPTGAIRLKDG 204
Fer4_16 pfam13484
4Fe-4S double cluster binding domain;
64-117 5.11e-04

4Fe-4S double cluster binding domain;


Pssm-ID: 463893 [Multi-domain]  Cd Length: 65  Bit Score: 37.08  E-value: 5.11e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 918020922   64 CIACEVCVRVCPI-----DLPVVDWRFERDIKKKQLLNYSID------FGICIFCGNCVEYCPTN 117
Cdd:pfam13484   1 CGSCGKCIDACPTgaivgPEGVLDARRCISYLTIEKKGLIPDelrcllGNRCYGCDICQDVCPWN 65
DsrA COG2221
Dissimilatory sulfite reductase (desulfoviridin), alpha and beta subunits [Inorganic ion ...
 99-124 5.24e-04

Dissimilatory sulfite reductase (desulfoviridin), alpha and beta subunits [Inorganic ion transport and metabolism];


Pssm-ID: 441823 [Multi-domain]  Cd Length: 69  Bit Score: 36.95  E-value: 5.24e-04
                         10        20
                 ....*....|....*....|....*.
gi 918020922  99 IDFGICIFCGNCVEYCPTNCLSMTEE 124
Cdd:COG2221   12 IDEEKCIGCGLCVAVCPTGAISLDDG 37
DMSOR_beta_like cd16374
uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the ...
 55-128 6.12e-04

uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the small beta iron-sulfur (FeS) subunit of the DMSO Reductase (DMSOR) family. Members of this family also contain a large, periplasmic molybdenum-containing alpha subunit and may have a small gamma subunit as well. Examples of heterodimeric members with alpha and beta subunits include arsenite oxidase, and tungsten-containing formate dehydrogenase (FDH-T) while heterotrimeric members containing alpha, beta, and gamma subunits include formate dehydrogenase-N (FDH-N), and nitrate reductase (NarGHI). The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.


Pssm-ID: 319896 [Multi-domain]  Cd Length: 139  Bit Score: 38.02  E-value: 6.12e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 918020922  55 GRIHFEFDKCIACEVCVRVCPIDLPVVDWRFERDIKkkqllnysidfgiCIFCGN---------CVEYCPTNCLSMTEEY 125
Cdd:cd16374   66 GAVLVDPDKCIGCGMCAMACPFGVPRFDPSLKVAVK-------------CDLCIDrrregklpaCVEACPTGALKFGDIE 132


                 ...
gi 918020922 126 ELS 128
Cdd:cd16374  133 ELL 135
COG2768 COG2768
Uncharacterized Fe-S cluster protein [Function unknown];
54-92 6.49e-04

Uncharacterized Fe-S cluster protein [Function unknown];


Pssm-ID: 442050 [Multi-domain]  Cd Length: 74  Bit Score: 37.02  E-value: 6.49e-04
                         10        20        30
                 ....*....|....*....|....*....|....*....
gi 918020922  54 RGRIHFEFDKCIACEVCVRVCPIDLPVVDWRFERDIKKK 92
Cdd:COG2768   32 DGKAVIDPEKCIGCGACIEVCPVGAIKIEWEEDEEFQEK 70
FDH_beta_like cd16366
beta FeS subunits of formate dehydrogenase N (FDH-N) and similar proteins; This family ...
 55-119 7.05e-04

beta FeS subunits of formate dehydrogenase N (FDH-N) and similar proteins; This family contains beta FeS subunits of several dehydrogenases in the DMSO reductase superfamily, including formate dehydrogenase N (FDH-N), tungsten-containing formate dehydrogenase (W-FDH) and other similar proteins. FDH-N is a major component of nitrate respiration of Escherichia coli; it catalyzes the oxidation of formate to carbon dioxide, donating the electrons to a second substrate to a cytochrome. W-FDH contains a tungsten instead of molybdenum at the catalytic center and seems to be exclusively found in organisms such as hyperthermophilic archaea that live in extreme environments. It catalyzes the oxidation of formate to carbon dioxide, donating the electrons to a second substrate.


Pssm-ID: 319888 [Multi-domain]  Cd Length: 156  Bit Score: 38.15  E-value: 7.05e-04
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 918020922  55 GRIHFEFDKCIACEVCVRVCPIDLPVVDWRFERDIKkkqllnysidfgiCIFC------GN---CVEYCPTNCL 119
Cdd:cd16366   93 GTVVVDPETCIGCGYCVNACPFDIPRFDEETGRVAK-------------CTLCydrisnGLqpaCVKTCPTGAL 153
FDH_b_like cd10562
uncharacterized subfamily of beta subunit of formate dehydrogenase; This subfamily includes ...
 55-119 8.47e-04

uncharacterized subfamily of beta subunit of formate dehydrogenase; This subfamily includes the beta-subunit of formate dehydrogenases that are as yet uncharacterized. Members of the DMSO reductase family include formate dehydrogenase N and O (FDH-N, FDH-O) and tungsten-containing formate dehydrogenase (W-FDH) and other similar proteins. FDH-N, a major component of nitrate respiration of Escherichia coli, is involved in the major anaerobic respiratory pathway in the presence of nitrate, catalyzing the oxidation of formate to carbon dioxide at the expense of nitrate reduction to nitrite. It forms a heterotrimer; the alpha-subunit (FDH-G) is the catalytic site of formate oxidation and membrane-associated, incorporating a selenocysteine (SeCys) residue and a [4Fe/4S] cluster in addition to two bis-MGD cofactors, the beta subunit (FDH-H) contains four [4Fe/4S] clusters which transfer the electrons from the alpha subunit to the gamma-subunit (FDH-I), a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. W-FDH contains a tungsten instead of molybdenum at the catalytic center. This enzyme seems to be exclusively found in organisms such as hyperthermophilic archaea that live in extreme environments. It is a heterodimer of a large and a small subunit; the large subunit harbors the W site and one [4Fe-4S] center and the small subunit, containing three [4Fe-4S] clusters, functions to transfer electrons.


Pssm-ID: 319884 [Multi-domain]  Cd Length: 161  Bit Score: 38.05  E-value: 8.47e-04
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 918020922  55 GRIHFEFDKCIACEVCVRVCPIDLPvvdwRFERDIKKKQLlnysidfgiCIFCGN---------CVEYCPTNCL 119
Cdd:cd10562   93 GAVVVDEDKCIGCGYCVAACPFDVP----RYDETTNKITK---------CTLCFDriengmqpaCVKTCPTGAL 153
Fer4_18 pfam13746
4Fe-4S dicluster domain; This family includes proteins containing domains which bind to ...
 64-132 8.80e-04

4Fe-4S dicluster domain; This family includes proteins containing domains which bind to iron-sulfur clusters. Members include bacterial ferredoxins, various dehydrogenases, and various reductases. The structure of the domain is an alpha-antiparallel beta sandwich.


Pssm-ID: 404610 [Multi-domain]  Cd Length: 114  Bit Score: 37.38  E-value: 8.80e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 918020922   64 CIACEVCVRVCPIDLpvvdwrferDIKKKQLLNysidfgiCIFCGNCVEYCPTNCLSMTEEYELSTYDR 132
Cdd:pfam13746  61 CIDCESCVQVCPTGI---------DIRKGLQLE-------CINCGLCIDACNTIMGKLGKPRGLIRYSS 113
DMSOR_beta-like cd04410
Beta subunit of the DMSO Reductase (DMSOR) family; This family consists of the small beta ...
 62-124 8.90e-04

Beta subunit of the DMSO Reductase (DMSOR) family; This family consists of the small beta iron-sulfur (FeS) subunit of the DMSO Reductase (DMSOR) family. Members of this family also contain a large, periplasmic molybdenum-containing alpha subunit and may have a small gamma subunit as well. Examples of heterodimeric members with alpha and beta subunits include arsenite oxidase, and tungsten-containing formate dehydrogenase (FDH-T) while heterotrimeric members containing alpha, beta, and gamma subunits include formate dehydrogenase-N (FDH-N), and nitrate reductase (NarGHI). The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.


Pssm-ID: 319870 [Multi-domain]  Cd Length: 136  Bit Score: 37.75  E-value: 8.90e-04
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 918020922  62 DKCIACEVCVRVCPIDLPVVDWRFERDIKKKQLLNYSIDF--GICIFCGN--CVEYCPTNCLSMTEE 124
Cdd:cd04410    6 DRCIGCGTCEVACKQEHGLRPGPDWSRIKVIEGGGLERAFlpVSCMHCEDppCVKACPTGAIYKDED 72
COG1149 COG1149
MinD superfamily P-loop ATPase, contains an inserted ferredoxin domain [General function ...
 99-124 1.09e-03

MinD superfamily P-loop ATPase, contains an inserted ferredoxin domain [General function prediction only];


Pssm-ID: 440763 [Multi-domain]  Cd Length: 68  Bit Score: 36.24  E-value: 1.09e-03
                         10        20
                 ....*....|....*....|....*.
gi 918020922  99 IDFGICIFCGNCVEYCPTNCLSMTEE 124
Cdd:COG1149    8 IDEEKCIGCGLCVEVCPEGAIKLDDG 33
DMSOR_beta_like cd16372
uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the ...
 64-125 1.12e-03

uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the small beta iron-sulfur (FeS) subunit of the DMSO Reductase (DMSOR) family. Members of this family also contain a large, periplasmic molybdenum-containing alpha subunit and may have a small gamma subunit as well. Examples of heterodimeric members with alpha and beta subunits include arsenite oxidase, and tungsten-containing formate dehydrogenase (FDH-T) while heterotrimeric members containing alpha, beta, and gamma subunits include formate dehydrogenase-N (FDH-N), and nitrate reductase (NarGHI). The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.


Pssm-ID: 319894 [Multi-domain]  Cd Length: 125  Bit Score: 37.32  E-value: 1.12e-03
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 918020922  64 CIACEVCVRVCPidlpvvdwrfERDIKKKQLLNYSIDFGICIFCGNCVEYCPTNCLSMTEEY 125
Cdd:cd16372   49 CNQCGECIDVCP----------TGAITRDANGVVMINKKLCVGCLMCVGFCPEGAMFKHEDY 100
PLN00071 PLN00071
photosystem I subunit VII; Provisional
 61-121 1.14e-03

photosystem I subunit VII; Provisional


Pssm-ID: 177700 [Multi-domain]  Cd Length: 81  Bit Score: 36.46  E-value: 1.14e-03
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 918020922  61 FDKCIACEVCVRVCPID-LPVVDWrferDIKKKQLLNYSIDFGICIFCGNCVEYCPTNCLSM 121
Cdd:PLN00071   8 YDTCIGCTQCVRACPTDvLEMIPW----DGCKAKQIASAPRTEDCVGCKRCESACPTDFLSV 65
PRK09326 PRK09326
F420H2 dehydrogenase subunit F; Provisional
 60-115 1.16e-03

F420H2 dehydrogenase subunit F; Provisional


Pssm-ID: 181779 [Multi-domain]  Cd Length: 341  Bit Score: 38.67  E-value: 1.16e-03
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 918020922  60 EFDKCIACEVCVRVCPIDLPVVDWRFE-RDIKKKQLLNYSIDFGICIFCGNCVEYCP 115
Cdd:PRK09326  10 EYDVCTACGACEAVCPIGAITVDKKAEiRDPNDLELYEKGAAPNVCEGCLTCSRICP 66
glpC PRK11168
anaerobic glycerol-3-phosphate dehydrogenase subunit C;
59-117 1.29e-03

anaerobic glycerol-3-phosphate dehydrogenase subunit C;


Pssm-ID: 236869 [Multi-domain]  Cd Length: 396  Bit Score: 38.31  E-value: 1.29e-03
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 918020922  59 FEFDKCIACEVCVRVCPIdLPVVD------------WRFERdiKKKQLLNYSIDFgiCIFCGNCVEYCPTN 117
Cdd:PRK11168   4 TSFDSCIKCTVCTTACPV-ARVNPlypgpkqagpdgERLRL--KDGALYDESLKY--CSNCKRCEVACPSG 69
PRK06991 PRK06991
electron transport complex subunit RsxB;
64-121 1.31e-03

electron transport complex subunit RsxB;


Pssm-ID: 235903 [Multi-domain]  Cd Length: 270  Bit Score: 38.24  E-value: 1.31e-03
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 918020922  64 CIACEVCVRVCPIDLPVVdwrferdiKKKQLlnYSIDFGICIFCGNCVEYCPTNCLSM 121
Cdd:PRK06991  87 CIGCTLCMQACPVDAIVG--------APKQM--HTVLADLCTGCDLCVPPCPVDCIDM 134
RnfB COG2878
Na+-translocating ferredoxin:NAD+ oxidoreductase RNF, RnfB subunit [Energy production and ...
 62-118 2.02e-03

Na+-translocating ferredoxin:NAD+ oxidoreductase RNF, RnfB subunit [Energy production and conversion]; Na+-translocating ferredoxin:NAD+ oxidoreductase RNF, RnfB subunit is part of the Pathway/BioSystem: Na+-translocating Fd:NADH oxidoreductase


Pssm-ID: 442125 [Multi-domain]  Cd Length: 254  Bit Score: 37.67  E-value: 2.02e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 918020922  62 DKCIACEVCVRVCPID----------LPVVDWRFERDIKKK-------------------QLLNYSIDFGICIFCGNCVE 112
Cdd:COG2878  167 DKCTGCGLCVEACPVDciemvpvsptVVVSSWDKGKAVRKVvgciglcckkccpaaaitvNNLAAIIDYKKCTCCGCCEK 246


                 ....*.
gi 918020922 113 YCPTNC 118
Cdd:COG2878  247 CCPTAI 252
dhsB TIGR00384
succinate dehydrogenase and fumarate reductase iron-sulfur protein; Succinate dehydrogenase ...
 24-117 2.27e-03

succinate dehydrogenase and fumarate reductase iron-sulfur protein; Succinate dehydrogenase and fumarate reductase are reverse directions of the same enzymatic interconversion, succinate + FAD+ = fumarate + FADH2 (EC 1.3.11.1). In E. coli, the forward and reverse reactions are catalyzed by distinct complexes: fumarate reductase operates under anaerobic conditions and succinate dehydrogenase operates under aerobic conditions. This model also describes a region of the B subunit of a cytosolic archaeal fumarate reductase. [Energy metabolism, Aerobic, Energy metabolism, Anaerobic, Energy metabolism, TCA cycle]


Pssm-ID: 273049 [Multi-domain]  Cd Length: 220  Bit Score: 37.41  E-value: 2.27e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 918020922   24 QSFVITLSHTNRLPITIQYP--YEKSitserfrgrihFEFDKCIACEVCVRVCPIDLPVVDW----------RF---ERD 88
Cdd:TIGR00384 109 KPYLIRKSQPEPEGEFLQTPeqREKL-----------DQLSGCILCGCCYSSCPAFWWNPEFlgpaaltaayRFlidSRD 177

                          90       100       110
                  ....*....|....*....|....*....|..
gi 918020922   89 I-KKKQLLNYSIDFGI--CIFCGNCVEYCPTN 117
Cdd:TIGR00384 178 HaTKDRLEGLNDKNGVwrCTTCMNCSEVCPKG 209
DMSOR_beta_like cd16372
uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the ...
 62-123 2.48e-03

uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the small beta iron-sulfur (FeS) subunit of the DMSO Reductase (DMSOR) family. Members of this family also contain a large, periplasmic molybdenum-containing alpha subunit and may have a small gamma subunit as well. Examples of heterodimeric members with alpha and beta subunits include arsenite oxidase, and tungsten-containing formate dehydrogenase (FDH-T) while heterotrimeric members containing alpha, beta, and gamma subunits include formate dehydrogenase-N (FDH-N), and nitrate reductase (NarGHI). The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.


Pssm-ID: 319894 [Multi-domain]  Cd Length: 125  Bit Score: 36.16  E-value: 2.48e-03
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 918020922  62 DKCIACEVCVRVCPIDLPVVDWRFERDIKkkqllnysidfgiCIFCGNCVEYCPTNCLSMTE 123
Cdd:cd16372   77 KLCVGCLMCVGFCPEGAMFKHEDYPEPFK-------------CIACGICVKACPTGALELVE 125
PRK07118 PRK07118
Fe-S cluster domain-containing protein;
64-122 2.89e-03

Fe-S cluster domain-containing protein;


Pssm-ID: 235941 [Multi-domain]  Cd Length: 280  Bit Score: 37.22  E-value: 2.89e-03
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 918020922  64 CIACEVCVRVCPID-------LPVVDwrferdiKKKqllnysidfgiCIFCGNCVEYCPTNCLSMT 122
Cdd:PRK07118 141 CLGLGSCVAACPFDaihiengLPVVD-------EDK-----------CTGCGACVKACPRNVIELI 188
PRK10882 PRK10882
hydrogenase 2 operon protein HybA;
55-116 3.46e-03

hydrogenase 2 operon protein HybA;


Pssm-ID: 236786 [Multi-domain]  Cd Length: 328  Bit Score: 36.96  E-value: 3.46e-03
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 918020922  55 GRIHFEFDKCIACEVCVRVCPIDLPVVDWR--FERdIKKKQLLNYS----IDFGicifcGN--CVEYCPT 116
Cdd:PRK10882 136 GIVHYDKDVCTGCRYCMVACPFNVPKYDYNnpFGA-IHKCELCNQKgverLDKG-----GLpgCVEVCPT 199
HycB_like cd10554
HycB, HydN and similar proteins; This family includes HycB, the FeS subunit of a ...
 55-121 3.63e-03

HycB, HydN and similar proteins; This family includes HycB, the FeS subunit of a membrane-associated formate hydrogenlyase system (FHL-1) in Escherichia coli that breaks down formate, produced during anaerobic fermentation, to H2 and CO2. FHL-1 consists of formate dehydrogenase H (FDH-H) and the hydrogenase 3 complex (Hyd-3). HycB is thought to code for the [4Fe-4S] ferredoxin subunit of hydrogenase 3, which functions as an intermediate electron carrier protein between hydrogenase 3 and formate dehydrogenase. HydN codes for the [4Fe-4S] ferredoxin subunit of FDH-H; a hydN in-frame deletion mutation causes only weak reduction in hydrogenase activity, but loss of more than 60% of FDH-H activity. This pathway is only active at low pH and high formate concentrations, and is thought to provide a detoxification/de-acidification system countering the buildup of formate during fermentation.


Pssm-ID: 319876 [Multi-domain]  Cd Length: 149  Bit Score: 36.08  E-value: 3.63e-03
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 918020922  55 GRIHFEFDKCIACEVCVRVCP---IDLPVVDWRFERDIKKKQLLNYSIDfgICIFCGN---CVEYCPTNCLSM 121
Cdd:cd10554   78 GVVQVDEERCIGCKLCVLACPfgaIEMAPTTVPGVDWERGPRAVAVKCD--LCAGREGgpaCVEACPTKALTL 148
PRK00783 PRK00783
DNA-directed RNA polymerase subunit D; Provisional
 56-124 4.57e-03

DNA-directed RNA polymerase subunit D; Provisional


Pssm-ID: 234837 [Multi-domain]  Cd Length: 263  Bit Score: 36.40  E-value: 4.57e-03
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 918020922  56 RIHFEfDKCIACEVCVRVCPIDLPVVDwrfERDIKKKQLLNysidfgiCIFCGNCVEYCPTNCLSMTEE 124
Cdd:PRK00783 164 RIEVS-EDCDECEKCVEACPRGVLELK---EGKLVVTDLLN-------CSLCKLCERACPGKAIRVSDD 221
DMSOR_beta_like cd16373
uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the ...
 60-120 4.69e-03

uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the small beta iron-sulfur (FeS) subunit of the DMSO Reductase (DMSOR) family. Members of this family also contain a large, periplasmic molybdenum-containing alpha subunit and may have a small gamma subunit as well. Examples of heterodimeric members with alpha and beta subunits include arsenite oxidase, and tungsten-containing formate dehydrogenase (FDH-T) while heterotrimeric members containing alpha, beta, and gamma subunits include formate dehydrogenase-N (FDH-N), and nitrate reductase (NarGHI). The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.


Pssm-ID: 319895 [Multi-domain]  Cd Length: 154  Bit Score: 36.08  E-value: 4.69e-03
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 918020922  60 EF-DKCIACEVCVRVCP---IDLPVVDWRFERDIKKKqlLNYSIDFgiCIFCGN-CVEYCPTNCLS 120
Cdd:cd16373   11 EFlALCIRCGLCVEACPtgvIQPAGLEDGLEGGRTPY--LDPREGP--CDLCCDaCVEVCPTGALR 72
GlpC COG0247
Fe-S cluster-containing oxidoreductase, includes glycolate oxidase subunit GlcF [Energy ...
 51-117 5.98e-03

Fe-S cluster-containing oxidoreductase, includes glycolate oxidase subunit GlcF [Energy production and conversion];


Pssm-ID: 440017 [Multi-domain]  Cd Length: 420  Bit Score: 36.59  E-value: 5.98e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 918020922  51 ERFRGRIHFEFDKCIACEVCVRVCPIDLPvvdWRFERDIKK------KQLLNYSIDFGI----------CIFCGNCVEYC 114
Cdd:COG0247   67 TLPWKELLDALDACVGCGFCRAMCPSYKA---TGDEKDSPRgrinllREVLEGELPLDLseevyevldlCLTCKACETAC 143


                 ...
gi 918020922 115 PTN 117
Cdd:COG0247  144 PSG 146
HybA_like cd10561
the FeS subunit of hydrogenase 2; This subfamily includes the beta-subunit of hydrogenase 2 ...
 62-116 6.08e-03

the FeS subunit of hydrogenase 2; This subfamily includes the beta-subunit of hydrogenase 2 (Hyd-2), an enzyme that catalyzes the reversible oxidation of H2 to protons and electrons. Hyd-2 is membrane-associated and forms an unusual heterotetrameric [NiFe]-hydrogenase in that it lacks the typical cytochrome b membrane anchor subunit that transfers electrons to the quinone pool. The electron transfer subunit of Hyd-2 (HybA) which is predicted to contain four iron-sulfur clusters, is essential for electron transfer from Hyd-2 to menaquinone/demethylmenaquinone (MQ/DMQ) to couple hydrogen oxidation to fumarate reduction.


Pssm-ID: 319883 [Multi-domain]  Cd Length: 196  Bit Score: 36.04  E-value: 6.08e-03
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 918020922  62 DKCIACEVCVRVCPIDLPvvdwRFERD-----IKKkqllnysidfgiCIFCGN---------CVEYCPT 116
Cdd:cd10561   99 DKCIGCRYCMVACPFNIP----KYEWDsanpkIRK------------CTMCYDrlkegkqpaCVEACPT 151
Fer4_17 pfam13534
4Fe-4S dicluster domain; This family includes proteins containing domains which bind to ...
 63-115 7.26e-03

4Fe-4S dicluster domain; This family includes proteins containing domains which bind to iron-sulfur clusters. Members include bacterial ferredoxins, various dehydrogenases, and various reductases. The structure of the domain is an alpha-antiparallel beta sandwich.


Pssm-ID: 433287 [Multi-domain]  Cd Length: 61  Bit Score: 33.59  E-value: 7.26e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 918020922   63 KCIACEVCVRVCP----IDLPVVDWRFERDIKKKQLLNYSIDFGICIFCGNCVEYCP 115
Cdd:pfam13534   1 RCIQCGCCVDECPryllNGDEPKKLMRAAYLGDLEELQANKVANLCSECGLCEYACP 57
Fer4_7 pfam12838
4Fe-4S dicluster domain; Superfamily includes proteins containing domains which bind to ...
 104-136 7.73e-03

4Fe-4S dicluster domain; Superfamily includes proteins containing domains which bind to iron-sulfur clusters. Members include bacterial ferredoxins, various dehydrogenases, and various reductases. Structure of the domain is an alpha-antiparallel beta sandwich. Domain contains two 4Fe4S clusters.


Pssm-ID: 463724 [Multi-domain]  Cd Length: 51  Bit Score: 33.27  E-value: 7.73e-03
                          10        20        30
                  ....*....|....*....|....*....|...
gi 918020922  104 CIFCGNCVEYCPTNCLSMTEEYELSTYDRHELN 136
Cdd:pfam12838   1 CIGCGACVAACPVGAITLDEVGEKKGTKTVVID 33
PhsB_like cd10553
uncharacterized beta subfamily of DMSO Reductase similar to Desulfonauticus sp PhsB; This ...
 55-122 8.90e-03

uncharacterized beta subfamily of DMSO Reductase similar to Desulfonauticus sp PhsB; This family includes beta FeS subunits of anaerobic DMSO reductase (DMSOR) superfamily that have yet to be characterized. DMSOR consists of a large, periplasmic molybdenum-containing alpha subunit as well as a small beta FeS subunit, and may also have a small gamma subunit. Examples of heterodimeric members with alpha and beta subunits include arsenite oxidase, and the tungsten-containing formate dehydrogenase (FDH-T). Examples of heterotrimeric members containing alpha, beta, and gamma subunits include formate dehydrogenase-N (FDH-N), and nitrate reductase (NarGHI). The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.


Pssm-ID: 319875 [Multi-domain]  Cd Length: 146  Bit Score: 35.03  E-value: 8.90e-03
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 918020922  55 GRIHFEFDKCIACEVCVRVCPIDLPVVDWRFERDIKkkqllnysidfgiCIFCGN---------CVEYCPTNCLSMT 122
Cdd:cd10553   82 GIVYVDQELCIGCKACIEACPWGIPQWNPATGKVVK-------------CDYCMDridqglkpaCVTGCTTHALSFV 145
RnfC COG4656
Na+-translocating ferredoxin:NAD+ oxidoreductase RNF, RnfC subunit [Energy production and ...
 64-117 9.19e-03

Na+-translocating ferredoxin:NAD+ oxidoreductase RNF, RnfC subunit [Energy production and conversion]; Na+-translocating ferredoxin:NAD+ oxidoreductase RNF, RnfC subunit is part of the Pathway/BioSystem: Na+-translocating Fd:NADH oxidoreductase


Pssm-ID: 443694 [Multi-domain]  Cd Length: 451  Bit Score: 35.88  E-value: 9.19e-03
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 918020922  64 CIACEVCVRVCPIDL-PV-VDWRFERDIKKKqLLNYSIDFgiCIFCGNCvEY-CPTN 117
Cdd:COG4656  366 CIRCGRCVDACPMGLlPQqLYWYARAGDFDK-AEEYNLMD--CIECGCC-SYvCPSK 418
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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