NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|916698701|ref|WP_051305792|]
View 

NAD(P)/FAD-dependent oxidoreductase [Desulfogranum mediterraneum]

Protein Classification

NAD(P)/FAD-dependent oxidoreductase( domain architecture ID 11449903)

NAD(P)/FAD-dependent oxidoreductase catalyzes the transfer of electrons from one molecule, the electron donor or reductant, to another molecule, the electron acceptor or oxidant; similar to Escherichia coli uncharacterized protein YhiN

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
YhiN COG2081
Predicted flavoprotein YhiN [General function prediction only];
7-413 4.79e-161

Predicted flavoprotein YhiN [General function prediction only];


:

Pssm-ID: 441684 [Multi-domain]  Cd Length: 402  Bit Score: 459.52  E-value: 4.79e-161
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 916698701   7 IVIGGGPAGLMAAGQAAAAGAETLVLEKMKRTGLKLRITGKGRCNLTNVAEVRDFINRFGPSGRFLRQAFARFFSEELMA 86
Cdd:COG2081    1 IVIGAGAAGLMAAITAAERGARVLLLEKNPKVGRKILISGGGRCNFTNSEPLPEFLNYYGGNPHFLKSALSRFTPEDLIA 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 916698701  87 FFEELGLELVTERGGRVFPASGKATEVAEQLRSWCTACGARIQTAQPVDGLVLRDGRVVGVRSQGKELECDAVVVATGGA 166
Cdd:COG2081   81 FFEGLGIETKEESSGRVFPDSSKASDILRALLAELREAGVEIRLRTRVTGIEKEDGGFGVETPDGETVRADAVVLATGGL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 916698701 167 SYPRTGSSGDGYHLLEAVGHTIIAPRQALVPLETSGVDTAKLADLNLRNIGVRllVNGKRRRQEFGEVLFTSFGLSGPVT 246
Cdd:COG2081  161 SYPKLGSTGDGYRLAEQFGHTITPLRPALVPLTLSEHFFKRLAGLSLKNVALS--VGGKKIASFRGELLFTHRGLSGPAI 238

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 916698701 247 LTLSGQVVDELRQGnGVSLSLDLKPALDEQKLEARLQRDIAGRGKEELQSLLRGLLPRELVPVCLKKtgLAADQLGFTIS 326
Cdd:COG2081  239 LQLSSYWRDALKKG-GATLTIDLLPDLDLEELDARLARPREKNGKKSLKNVLRGLLPKRLAALLLEL--ADPDKPLAQLS 315

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 916698701 327 AKQRRRLRSWLKDFRLDVRRPRPLAEAIVTAGGVDTREIDPRTMGSKKVAGLYVVGELLDLQADTGGYNLQAAFSTGWLA 406
Cdd:COG2081  316 KKEREALAALLKAWPLTPTGTRGYDEAIVTAGGVDTKELDPKTMESKKVPGLYFAGEVLDVDGPTGGYNLQWAWSSGYAA 395


                 ....*..
gi 916698701 407 GRSAAER 413
Cdd:COG2081  396 GQAAAAW 402
 
Name Accession Description Interval E-value
YhiN COG2081
Predicted flavoprotein YhiN [General function prediction only];
7-413 4.79e-161

Predicted flavoprotein YhiN [General function prediction only];


Pssm-ID: 441684 [Multi-domain]  Cd Length: 402  Bit Score: 459.52  E-value: 4.79e-161
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 916698701   7 IVIGGGPAGLMAAGQAAAAGAETLVLEKMKRTGLKLRITGKGRCNLTNVAEVRDFINRFGPSGRFLRQAFARFFSEELMA 86
Cdd:COG2081    1 IVIGAGAAGLMAAITAAERGARVLLLEKNPKVGRKILISGGGRCNFTNSEPLPEFLNYYGGNPHFLKSALSRFTPEDLIA 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 916698701  87 FFEELGLELVTERGGRVFPASGKATEVAEQLRSWCTACGARIQTAQPVDGLVLRDGRVVGVRSQGKELECDAVVVATGGA 166
Cdd:COG2081   81 FFEGLGIETKEESSGRVFPDSSKASDILRALLAELREAGVEIRLRTRVTGIEKEDGGFGVETPDGETVRADAVVLATGGL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 916698701 167 SYPRTGSSGDGYHLLEAVGHTIIAPRQALVPLETSGVDTAKLADLNLRNIGVRllVNGKRRRQEFGEVLFTSFGLSGPVT 246
Cdd:COG2081  161 SYPKLGSTGDGYRLAEQFGHTITPLRPALVPLTLSEHFFKRLAGLSLKNVALS--VGGKKIASFRGELLFTHRGLSGPAI 238

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 916698701 247 LTLSGQVVDELRQGnGVSLSLDLKPALDEQKLEARLQRDIAGRGKEELQSLLRGLLPRELVPVCLKKtgLAADQLGFTIS 326
Cdd:COG2081  239 LQLSSYWRDALKKG-GATLTIDLLPDLDLEELDARLARPREKNGKKSLKNVLRGLLPKRLAALLLEL--ADPDKPLAQLS 315

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 916698701 327 AKQRRRLRSWLKDFRLDVRRPRPLAEAIVTAGGVDTREIDPRTMGSKKVAGLYVVGELLDLQADTGGYNLQAAFSTGWLA 406
Cdd:COG2081  316 KKEREALAALLKAWPLTPTGTRGYDEAIVTAGGVDTKELDPKTMESKKVPGLYFAGEVLDVDGPTGGYNLQWAWSSGYAA 395


                 ....*..
gi 916698701 407 GRSAAER 413
Cdd:COG2081  396 GQAAAAW 402
TIGR00275 TIGR00275
flavoprotein, HI0933 family; The model when searched with a partial length search brings in ...
 7-408 8.78e-157

flavoprotein, HI0933 family; The model when searched with a partial length search brings in proteins with a dinucleotide-binding motif (Rossman fold) over the initial 40 residues of the model, including oxidoreductases and dehydrogenases. Partially characterized members include an FAD-binding protein from Bacillus cereus and flavoprotein HI0933 from Haemophilus influenzae. [Unknown function, Enzymes of unknown specificity]


Pssm-ID: 272992 [Multi-domain]  Cd Length: 400  Bit Score: 448.58  E-value: 8.78e-157
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 916698701    7 IVIGGGPAGLMAAGQAAAAGAETLVLEKMKRTGLKLRITGKGRCNLTNVAEVRDFINRFGPSGRFLRQAFARFFSEELMA 86
Cdd:TIGR00275   1 IIIGGGAAGLMAAITAARAGLSVLLLEKNKKIGKKLLISGGGRCNLTNSCPTPEFVAYYPRNGKFLRSALSRFSNKDLID 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 916698701   87 FFEELGLELVTERGGRVFPASGKATEVAEQLRSWCTACGARIQTAQPVDGLVlRDGRVVGVRSQGKELECDAVVVATGGA 166
Cdd:TIGR00275  81 FFESLGLELKVEEDGRVFPCSDSAADVLDALLNELKELGVEILTNSKVKSIE-KEDGGFGVETSGGEYEADKVIIATGGL 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 916698701  167 SYPRTGSSGDGYHLLEAVGHTIIAPRQALVPLETSGVDTAKLADLNLRNIgVRLLVNGKRRRQEFGEVLFTSFGLSGPVT 246
Cdd:TIGR00275 160 SYPQLGSTGDGYEIAESLGHTIVPPVPALVPLTLDESFLKELSGISLDGV-VLSLVNGKKVLEEFGELLFTHFGLSGPAI 238

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 916698701  247 LTLSGQVVDELRQGNGVSLSLDLKPALDEQKLEARLQRDIAGRGKEELQSLLRGLLPRELVPVCLKKTGLAADQLGFTIS 326
Cdd:TIGR00275 239 LDLSAFAARALLKHKGVELEIDLLPDLSEEELEQRLKRLRKSNPKKTVKNILKGLLPKRLAELLLEQLGIDPDLPAAQLS 318

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 916698701  327 AKQRRRLRSWLKDFRLDVRRPRPLAEAIVTAGGVDTREIDPRTMGSKKVAGLYVVGELLDLQADTGGYNLQAAFSTGWLA 406
Cdd:TIGR00275 319 KKEIKKLVQLLKNWPFTISGTRGFKEAEVTAGGVSLKEINPKTMESKLVPGLYFAGEVLDIDGDTGGYNLQWAWSSGYLA 398


                  ..
gi 916698701  407 GR 408
Cdd:TIGR00275 399 GK 400
HI0933_like pfam03486
HI0933-like protein;
4-409 9.22e-151

HI0933-like protein;


Pssm-ID: 427330 [Multi-domain]  Cd Length: 406  Bit Score: 433.55  E-value: 9.22e-151
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 916698701    4 RKVIVIGGGPAGLMAAGQAAAAGAETLVLEKMKRTGLKLRITGKGRCNLTNV-AEVRDFINRFGPSGRFLRQAFARFFSE 82
Cdd:pfam03486   1 FDVIVIGGGAAGLMAAISAAKRGRRVLLIEKGKKLGRKILISGGGRCNVTNLsEEPDNFLSRYPGNPKFLKSALSRFTPW 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 916698701   83 ELMAFFEELGLELVTERGGRVFPASGKATEVAEQLRSWCTACGARIQTAQPVDGLVLRDGRVVGVRSQGKELECDAVVVA 162
Cdd:pfam03486  81 DFIAFFESLGVPLKEEDHGRLFPDSDKASDIVDALLNELKELGVKIRLRTRVLSVEKDDDGRFRVKTGGEELEADSLVLA 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 916698701  163 TGGASYPRTGSSGDGYHLLEAVGHTIIAPRQALVPLET--SGVDTAKLADLNLRNIgvrLLVNGKRRRQEFGEVLFTSFG 240
Cdd:pfam03486 161 TGGLSWPKTGSTGFGYPLAEQFGHTIIPLRPALVPFTIdePFLFLKRLSGISLKNV---VLSNGKGGITFRGELLFTHRG 237

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 916698701  241 LSGPVTLTLSGQVVDELRQGNGVSLSLDLKPALDEQKLEARLQRDIAGRGKEELQSLLRGLLPRELVPVCLKKTGLAADQ 320
Cdd:pfam03486 238 LSGPAILQLSSYWRRAILKKGGVTLSIDLLPDLDAEELAARLEKPRGAHPKKSLKNSLAGLLPKRLAEFLLEQAGIEPDK 317

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 916698701  321 LGFTISAKQRRRLRSWLKDFRLDVRRPRPLAEAIVTAGGVDTREIDPRTMGSKKVAGLYVVGELLDLQADTGGYNLQAAF 400
Cdd:pfam03486 318 KLAQLSKKELAALAQLLKAWTFTPNGTEGYRTAEVTAGGVDTKELSSKTMESKKVPGLFFAGEVLDVDGWTGGYNLQWAW 397


                  ....*....
gi 916698701  401 STGWLAGRS 409
Cdd:pfam03486 398 SSGYAAGQG 406
PRK07233 PRK07233
hypothetical protein; Provisional
 113-163 7.08e-06

hypothetical protein; Provisional


Pssm-ID: 235977 [Multi-domain]  Cd Length: 434  Bit Score: 47.96  E-value: 7.08e-06
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|.
gi 916698701 113 VAEQLRSWCTACGARIQTAQPVDGLVLRDGRVVGVRSQGKELECDAVVVAT 163
Cdd:PRK07233 200 LIDALAEAIEARGGEIRLGTPVTSVVIDGGGVTGVEVDGEEEDFDAVISTA 250
 
Name Accession Description Interval E-value
YhiN COG2081
Predicted flavoprotein YhiN [General function prediction only];
7-413 4.79e-161

Predicted flavoprotein YhiN [General function prediction only];


Pssm-ID: 441684 [Multi-domain]  Cd Length: 402  Bit Score: 459.52  E-value: 4.79e-161
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 916698701   7 IVIGGGPAGLMAAGQAAAAGAETLVLEKMKRTGLKLRITGKGRCNLTNVAEVRDFINRFGPSGRFLRQAFARFFSEELMA 86
Cdd:COG2081    1 IVIGAGAAGLMAAITAAERGARVLLLEKNPKVGRKILISGGGRCNFTNSEPLPEFLNYYGGNPHFLKSALSRFTPEDLIA 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 916698701  87 FFEELGLELVTERGGRVFPASGKATEVAEQLRSWCTACGARIQTAQPVDGLVLRDGRVVGVRSQGKELECDAVVVATGGA 166
Cdd:COG2081   81 FFEGLGIETKEESSGRVFPDSSKASDILRALLAELREAGVEIRLRTRVTGIEKEDGGFGVETPDGETVRADAVVLATGGL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 916698701 167 SYPRTGSSGDGYHLLEAVGHTIIAPRQALVPLETSGVDTAKLADLNLRNIGVRllVNGKRRRQEFGEVLFTSFGLSGPVT 246
Cdd:COG2081  161 SYPKLGSTGDGYRLAEQFGHTITPLRPALVPLTLSEHFFKRLAGLSLKNVALS--VGGKKIASFRGELLFTHRGLSGPAI 238

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 916698701 247 LTLSGQVVDELRQGnGVSLSLDLKPALDEQKLEARLQRDIAGRGKEELQSLLRGLLPRELVPVCLKKtgLAADQLGFTIS 326
Cdd:COG2081  239 LQLSSYWRDALKKG-GATLTIDLLPDLDLEELDARLARPREKNGKKSLKNVLRGLLPKRLAALLLEL--ADPDKPLAQLS 315

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 916698701 327 AKQRRRLRSWLKDFRLDVRRPRPLAEAIVTAGGVDTREIDPRTMGSKKVAGLYVVGELLDLQADTGGYNLQAAFSTGWLA 406
Cdd:COG2081  316 KKEREALAALLKAWPLTPTGTRGYDEAIVTAGGVDTKELDPKTMESKKVPGLYFAGEVLDVDGPTGGYNLQWAWSSGYAA 395


                 ....*..
gi 916698701 407 GRSAAER 413
Cdd:COG2081  396 GQAAAAW 402
TIGR00275 TIGR00275
flavoprotein, HI0933 family; The model when searched with a partial length search brings in ...
 7-408 8.78e-157

flavoprotein, HI0933 family; The model when searched with a partial length search brings in proteins with a dinucleotide-binding motif (Rossman fold) over the initial 40 residues of the model, including oxidoreductases and dehydrogenases. Partially characterized members include an FAD-binding protein from Bacillus cereus and flavoprotein HI0933 from Haemophilus influenzae. [Unknown function, Enzymes of unknown specificity]


Pssm-ID: 272992 [Multi-domain]  Cd Length: 400  Bit Score: 448.58  E-value: 8.78e-157
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 916698701    7 IVIGGGPAGLMAAGQAAAAGAETLVLEKMKRTGLKLRITGKGRCNLTNVAEVRDFINRFGPSGRFLRQAFARFFSEELMA 86
Cdd:TIGR00275   1 IIIGGGAAGLMAAITAARAGLSVLLLEKNKKIGKKLLISGGGRCNLTNSCPTPEFVAYYPRNGKFLRSALSRFSNKDLID 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 916698701   87 FFEELGLELVTERGGRVFPASGKATEVAEQLRSWCTACGARIQTAQPVDGLVlRDGRVVGVRSQGKELECDAVVVATGGA 166
Cdd:TIGR00275  81 FFESLGLELKVEEDGRVFPCSDSAADVLDALLNELKELGVEILTNSKVKSIE-KEDGGFGVETSGGEYEADKVIIATGGL 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 916698701  167 SYPRTGSSGDGYHLLEAVGHTIIAPRQALVPLETSGVDTAKLADLNLRNIgVRLLVNGKRRRQEFGEVLFTSFGLSGPVT 246
Cdd:TIGR00275 160 SYPQLGSTGDGYEIAESLGHTIVPPVPALVPLTLDESFLKELSGISLDGV-VLSLVNGKKVLEEFGELLFTHFGLSGPAI 238

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 916698701  247 LTLSGQVVDELRQGNGVSLSLDLKPALDEQKLEARLQRDIAGRGKEELQSLLRGLLPRELVPVCLKKTGLAADQLGFTIS 326
Cdd:TIGR00275 239 LDLSAFAARALLKHKGVELEIDLLPDLSEEELEQRLKRLRKSNPKKTVKNILKGLLPKRLAELLLEQLGIDPDLPAAQLS 318

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 916698701  327 AKQRRRLRSWLKDFRLDVRRPRPLAEAIVTAGGVDTREIDPRTMGSKKVAGLYVVGELLDLQADTGGYNLQAAFSTGWLA 406
Cdd:TIGR00275 319 KKEIKKLVQLLKNWPFTISGTRGFKEAEVTAGGVSLKEINPKTMESKLVPGLYFAGEVLDIDGDTGGYNLQWAWSSGYLA 398


                  ..
gi 916698701  407 GR 408
Cdd:TIGR00275 399 GK 400
HI0933_like pfam03486
HI0933-like protein;
4-409 9.22e-151

HI0933-like protein;


Pssm-ID: 427330 [Multi-domain]  Cd Length: 406  Bit Score: 433.55  E-value: 9.22e-151
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 916698701    4 RKVIVIGGGPAGLMAAGQAAAAGAETLVLEKMKRTGLKLRITGKGRCNLTNV-AEVRDFINRFGPSGRFLRQAFARFFSE 82
Cdd:pfam03486   1 FDVIVIGGGAAGLMAAISAAKRGRRVLLIEKGKKLGRKILISGGGRCNVTNLsEEPDNFLSRYPGNPKFLKSALSRFTPW 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 916698701   83 ELMAFFEELGLELVTERGGRVFPASGKATEVAEQLRSWCTACGARIQTAQPVDGLVLRDGRVVGVRSQGKELECDAVVVA 162
Cdd:pfam03486  81 DFIAFFESLGVPLKEEDHGRLFPDSDKASDIVDALLNELKELGVKIRLRTRVLSVEKDDDGRFRVKTGGEELEADSLVLA 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 916698701  163 TGGASYPRTGSSGDGYHLLEAVGHTIIAPRQALVPLET--SGVDTAKLADLNLRNIgvrLLVNGKRRRQEFGEVLFTSFG 240
Cdd:pfam03486 161 TGGLSWPKTGSTGFGYPLAEQFGHTIIPLRPALVPFTIdePFLFLKRLSGISLKNV---VLSNGKGGITFRGELLFTHRG 237

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 916698701  241 LSGPVTLTLSGQVVDELRQGNGVSLSLDLKPALDEQKLEARLQRDIAGRGKEELQSLLRGLLPRELVPVCLKKTGLAADQ 320
Cdd:pfam03486 238 LSGPAILQLSSYWRRAILKKGGVTLSIDLLPDLDAEELAARLEKPRGAHPKKSLKNSLAGLLPKRLAEFLLEQAGIEPDK 317

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 916698701  321 LGFTISAKQRRRLRSWLKDFRLDVRRPRPLAEAIVTAGGVDTREIDPRTMGSKKVAGLYVVGELLDLQADTGGYNLQAAF 400
Cdd:pfam03486 318 KLAQLSKKELAALAQLLKAWTFTPNGTEGYRTAEVTAGGVDTKELSSKTMESKKVPGLFFAGEVLDVDGWTGGYNLQWAW 397


                  ....*....
gi 916698701  401 STGWLAGRS 409
Cdd:pfam03486 398 SSGYAAGQG 406
DadA COG0665
Glycine/D-amino acid oxidase (deaminating) [Amino acid transport and metabolism];
82-167 2.03e-07

Glycine/D-amino acid oxidase (deaminating) [Amino acid transport and metabolism];


Pssm-ID: 440429 [Multi-domain]  Cd Length: 364  Bit Score: 52.60  E-value: 2.03e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 916698701  82 EELMAFFEELGLE-----LVTERGGRVFPAsgkatEVAEQLRSWCTACGARIQTAQPVDGLVLRDGRVVGVRSQGKELEC 156
Cdd:COG0665  122 AELREREPGLGSPdyaggLYDPDDGHVDPA-----KLVRALARAARAAGVRIREGTPVTGLEREGGRVTGVRTERGTVRA 196

                         90
                 ....*....|.
gi 916698701 157 DAVVVATGGAS 167
Cdd:COG0665  197 DAVVLAAGAWS 207
SdhA COG1053
Succinate dehydrogenase/fumarate reductase, flavoprotein subunit [Energy production and ...
 73-185 1.47e-06

Succinate dehydrogenase/fumarate reductase, flavoprotein subunit [Energy production and conversion]; Succinate dehydrogenase/fumarate reductase, flavoprotein subunit is part of the Pathway/BioSystem: TCA cycle


Pssm-ID: 440673 [Multi-domain]  Cd Length: 443  Bit Score: 50.22  E-value: 1.47e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 916698701  73 RQAFARFF---SEELMAFFEELGLELVTERGGRV------------FPASGKATEVAEQLRSWCTACGARIQTAQPVDGL 137
Cdd:COG1053   81 DQDLVEALaeeAPEAIDWLEAQGVPFSRTPDGRLpqfgghsvgrtcYAGDGTGHALLATLYQAALRLGVEIFTETEVLDL 160

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 916698701 138 VLRDGRVVGVRSQGK-----ELECDAVVVATGGAS---------YPRT---------GSSGDGYHLLEAVG 185
Cdd:COG1053  161 IVDDGRVVGVVARDRtgeivRIRAKAVVLATGGFGrnyemraeyLPEAegalstnapGNTGDGIAMALRAG 231
COG1233 COG1233
Phytoene dehydrogenase-related protein [Secondary metabolites biosynthesis, transport and ...
 58-171 6.52e-06

Phytoene dehydrogenase-related protein [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 440846 [Multi-domain]  Cd Length: 491  Bit Score: 48.31  E-value: 6.52e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 916698701  58 VRDFINRFGPSGRfLRQAFARFF-----SEELMAFFeeLGLELVTERGGRVFPASGKATEVAEQLRSWCTACGARIQTAQ 132
Cdd:COG1233  167 LRDLLRRYFKDPR-LRALLAGQAlylglSPDRTPAL--YALIAYLEYAGGVWYPKGGMGALADALARLAEELGGEIRTGA 243

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|
gi 916698701 133 PVDGLVLRDGRVVGVR-SQGKELECDAVVVatgGASYPRT 171
Cdd:COG1233  244 EVERILVEGGRATGVRlADGEEIRADAVVS---NADPAHT 280
PRK07233 PRK07233
hypothetical protein; Provisional
 113-163 7.08e-06

hypothetical protein; Provisional


Pssm-ID: 235977 [Multi-domain]  Cd Length: 434  Bit Score: 47.96  E-value: 7.08e-06
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|.
gi 916698701 113 VAEQLRSWCTACGARIQTAQPVDGLVLRDGRVVGVRSQGKELECDAVVVAT 163
Cdd:PRK07233 200 LIDALAEAIEARGGEIRLGTPVTSVVIDGGGVTGVEVDGEEEDFDAVISTA 250
NirB COG1251
NAD(P)H-nitrite reductase, large subunit [Energy production and conversion];
90-164 1.41e-05

NAD(P)H-nitrite reductase, large subunit [Energy production and conversion];


Pssm-ID: 440863 [Multi-domain]  Cd Length: 402  Bit Score: 47.06  E-value: 1.41e-05
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 916698701  90 ELGLElVT--ERGGRVFPASGkATEVAEQLRSWCTACGARIQTAQPVDGlVLRDGRVVGVR-SQGKELECDAVVVATG 164
Cdd:COG1251  163 KRGLE-VTvvERAPRLLPRQL-DEEAGALLQRLLEALGVEVRLGTGVTE-IEGDDRVTGVRlADGEELPADLVVVAIG 237
PRK12842 PRK12842
putative succinate dehydrogenase; Reviewed
 99-185 1.08e-04

putative succinate dehydrogenase; Reviewed


Pssm-ID: 237224 [Multi-domain]  Cd Length: 574  Bit Score: 44.30  E-value: 1.08e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 916698701  99 RGGRVfpASGKAteVAEQLRSWCTACGARIQTAQPVDGLVLRDGRVVGVRSQGKELECD-----AVVVATGGAS------ 167
Cdd:PRK12842 206 RGTQV--TSGNA--LAARLAKSALDLGIPILTGTPARELLTEGGRVVGARVIDAGGERRitarrGVVLACGGFShdlari 281

                         90       100       110
                 ....*....|....*....|....*....|...
gi 916698701 168 ---YPR------------TGSSGDGYHLLEAVG 185
Cdd:PRK12842 282 araYPHlarggehlspvpAGNTGDGIRLAEAVG 314
FadH2 COG0446
NADPH-dependent 2,4-dienoyl-CoA reductase, sulfur reductase, or a related oxidoreductase ...
 83-164 1.97e-04

NADPH-dependent 2,4-dienoyl-CoA reductase, sulfur reductase, or a related oxidoreductase [Lipid transport and metabolism];


Pssm-ID: 440215 [Multi-domain]  Cd Length: 322  Bit Score: 43.26  E-value: 1.97e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 916698701  83 ELMAFFEELGLEL-VTERGGRVFPASGKatEVAEQLRSWCTACGARIQTAQPVDGlVLRDGRVVGVRSQGKELECDAVVV 161
Cdd:COG0446  138 ELAEALRKRGLKVtLVERAPRLLGVLDP--EMAALLEEELREHGVELRLGETVVA-IDGDDKVAVTLTDGEEIPADLVVV 214


                 ...
gi 916698701 162 ATG 164
Cdd:COG0446  215 APG 217
PRK10157 PRK10157
putative oxidoreductase FixC; Provisional
 78-164 8.67e-04

putative oxidoreductase FixC; Provisional


Pssm-ID: 182273 [Multi-domain]  Cd Length: 428  Bit Score: 41.43  E-value: 8.67e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 916698701  78 RFFSEELMAFFEELGLELVTERGGRVFPASGKATEVaeqLRS----W----CTACGARIQTAQPVDGLVLRDGRVVGVRS 149
Cdd:PRK10157  70 RLITHEKLAFMTEKSAMTMDYCNGDETSPSQRSYSV---LRSkfdaWlmeqAEEAGAQLITGIRVDNLVQRDGKVVGVEA 146

                         90
                 ....*....|....*
gi 916698701 150 QGKELECDAVVVATG 164
Cdd:PRK10157 147 DGDVIEAKTVILADG 161
PRK08274 PRK08274
FAD-dependent tricarballylate dehydrogenase TcuA;
99-166 9.23e-04

FAD-dependent tricarballylate dehydrogenase TcuA;


Pssm-ID: 236214 [Multi-domain]  Cd Length: 466  Bit Score: 41.40  E-value: 9.23e-04
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 916698701  99 RGGRVFPASGKAteVAEQLRSWCTACGARIQTAQPVDGLVLRDGRVVGVRS-----QGKELECDAVVVATGGA 166
Cdd:PRK08274 121 RTNAFFWGGGKA--LVNALYRSAERLGVEIRYDAPVTALELDDGRFVGARAgsaagGAERIRAKAVVLAAGGF 191
FAD_binding_2 pfam00890
FAD binding domain; This family includes members that bind FAD. This family includes the ...
 72-395 1.49e-03

FAD binding domain; This family includes members that bind FAD. This family includes the flavoprotein subunits from succinate and fumarate dehydrogenase, aspartate oxidase and the alpha subunit of adenylylsulphate reductase.


Pssm-ID: 395718 [Multi-domain]  Cd Length: 398  Bit Score: 40.73  E-value: 1.49e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 916698701   72 LRQAFARFfSEELMAFFEELGLELVTERGGRVfpasgKATEVAEQLRSWCTACGA------------------------- 126
Cdd:pfam00890  78 YVEAFVEA-APEAVDWLEALGVPFSRTEDGHL-----DLRPLGGLSATWRTPHDAadrrrglgtghallarlleglrkag 151

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 916698701  127 -RIQTAQPVDGLVLRDGRVVGV----RSQGKELEC---DAVVVATGGAS-----------YPRT----GSSGDGYHLLEA 183
Cdd:pfam00890 152 vDFQPRTAADDLIVEDGRVTGAvvenRRNGREVRIraiAAVLLATGGFGrlaelllpaagYADTtnppANTGDGLALALR 231

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 916698701  184 VGhtiiaprqalVPLETSGVDTAKLADLNLRNIGVRLLVNGKRRRQEfGEVLFTSFGLSGPVTLTLSGQVVD-----ELR 258
Cdd:pfam00890 232 AG----------AALTDDLMEFVQFHPTSLVGIRLGSGLLIEALRGE-GGILVNKDGRRFMNELASRDVVSRaitrnEID 300

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 916698701  259 QGNGVSLSLDLKPALDEQKLEARLQRDIAgrgkeelqsllrgllprelvpvclkktgLAADQLGFTIsakqrrrlrswlk 338
Cdd:pfam00890 301 EGRGANVYLDASGSLDAEGLEATLPAINE----------------------------EAIFGLDVDP------------- 339

                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 916698701  339 dfrldVRRPRPL-AEAIVTAGGVDTREiDPRTM--GSKKVAGLYVVGEllDLQADTGGYN 395
Cdd:pfam00890 340 -----YDRPIPVfPAQHYTMGGVRTDE-NGRVLdaDGQPIPGLYAAGE--VACGGVHGAN 391
PRK00711 PRK00711
D-amino acid dehydrogenase;
111-167 2.07e-03

D-amino acid dehydrogenase;


Pssm-ID: 234819 [Multi-domain]  Cd Length: 416  Bit Score: 40.17  E-value: 2.07e-03
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 916698701 111 TEVAEQLrswctacGARIQTAQPVDGLVLRDGRVVGVRSQGKELECDAVVVATGGAS 167
Cdd:PRK00711 208 AAMAEQL-------GVKFRFNTPVDGLLVEGGRITGVQTGGGVITADAYVVALGSYS 257
NadB COG0029
Aspartate oxidase [Coenzyme transport and metabolism]; Aspartate oxidase is part of the ...
 134-178 2.42e-03

Aspartate oxidase [Coenzyme transport and metabolism]; Aspartate oxidase is part of the Pathway/BioSystem: NAD biosynthesis


Pssm-ID: 439800 [Multi-domain]  Cd Length: 521  Bit Score: 40.09  E-value: 2.42e-03
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 916698701 134 VDGLVLRDGRVVGV------RSQGKELECDAVVVATGGAS--YPRT----GSSGDGY 178
Cdd:COG0029  155 VDLITDADGRCVGAyvldekTGEVETIRAKAVVLATGGAGqlYAYTtnpdVATGDGI 211
Amino_oxidase pfam01593
Flavin containing amine oxidoreductase; This family consists of various amine oxidases, ...
 48-163 8.33e-03

Flavin containing amine oxidoreductase; This family consists of various amine oxidases, including maze polyamine oxidase (PAO)and various flavin containing monoamine oxidases (MAO). The aligned region includes the flavin binding site of these enzymes. The family also contains phytoene dehydrogenases and related enzymes. In vertebrates MAO plays an important role regulating the intracellular levels of amines via there oxidation; these include various neurotransmitters, neurotoxins and trace amines. In lower eukaryotes such as aspergillus and in bacteria the main role of amine oxidases is to provide a source of ammonium. PAOs in plants, bacteria and protozoa oxidase spermidine and spermine to an aminobutyral, diaminopropane and hydrogen peroxide and are involved in the catabolism of polyamines. Other members of this family include tryptophan 2-monooxygenase, putrescine oxidase, corticosteroid binding proteins and antibacterial glycoproteins.


Pssm-ID: 396255 [Multi-domain]  Cd Length: 446  Bit Score: 38.24  E-value: 8.33e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 916698701   48 GRCNLTNVAEVRDFINRFGPS-GRFLRQAFARFFSEELMAFFEELGLELVTERGGRVFPASGKAtEVAEQLRSwcTACGA 126
Cdd:pfam01593 143 GRRGPGDVEVWDRLIDPELFAaLPFASGAFAGDPSELSAGLALPLLWALLGEGGSLLLPRGGLG-ALPDALAA--QLLGG 219

                          90       100       110
                  ....*....|....*....|....*....|....*..
gi 916698701  127 RIQTAQPVDGLVLRDGRVVGVRSQGKELECDAVVVAT 163
Cdd:pfam01593 220 DVRLNTRVRSIDREGDGVTVTLTDGEVIEADAVIVTV 256
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH