|
Name |
Accession |
Description |
Interval |
E-value |
| ModF |
COG1119 |
ABC-type molybdenum transport system, ATPase component ModF/photorepair protein PhrA ... |
4-248 |
3.86e-111 |
|
ABC-type molybdenum transport system, ATPase component ModF/photorepair protein PhrA [Inorganic ion transport and metabolism];
Pssm-ID: 440736 [Multi-domain] Cd Length: 250 Bit Score: 320.11 E-value: 3.86e-111
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 4 NAVLSMKNVSFER-DKIILKNINWSLHSGENWVLMGLNGAGKTTLLSLIYGNHWATTG-SIEVLGETFGKTNVLALKKRI 81
Cdd:COG1119 1 DPLLELRNVTVRRgGKTILDDISWTVKPGEHWAILGPNGAGKSTLLSLITGDLPPTYGnDVRLFGERRGGEDVWELRKRI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 82 GLISTAVQSQFPEHHLAQYIVLSGKFGTIGIHNDFEKNDLNEAIGLLKKLGGDELVNKPYRVLSQGQRQLVLIARALLGK 161
Cdd:COG1119 81 GLVSPALQLRFPRDETVLDVVLSGFFDSIGLYREPTDEQRERARELLELLGLAHLADRPFGTLSQGEQRRVLIARALVKD 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 162 PELLILDEPCNGLDLFSRELLLEQINKLAQLPNhPTLLFVSHYTEEILPIFKNIMLLKQGEIFAQGTRDKILTENVLSKF 241
Cdd:COG1119 161 PELLILDEPTAGLDLGARELLLALLDKLAAEGA-PTLVLVTHHVEEIPPGITHVLLLKDGRVVAAGPKEEVLTSENLSEA 239
|
....*..
gi 915796356 242 YPKPIKI 248
Cdd:COG1119 240 FGLPVEV 246
|
|
| ZnuC |
COG1121 |
ABC-type Mn2+/Zn2+ transport system, ATPase component [Inorganic ion transport and metabolism]; ... |
1-249 |
2.57e-51 |
|
ABC-type Mn2+/Zn2+ transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 440738 [Multi-domain] Cd Length: 245 Bit Score: 167.96 E-value: 2.57e-51
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 1 MTNNAVLSMKNVSFE-RDKIILKNINWSLHSGENWVLMGLNGAGKTTLLSLIYGNHWATTGSIEVLGETFGKTnvlalKK 79
Cdd:COG1121 1 MMMMPAIELENLTVSyGGRPVLEDVSLTIPPGEFVAIVGPNGAGKSTLLKAILGLLPPTSGTVRLFGKPPRRA-----RR 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 80 RIGLI--STAVQSQFP----EhhlaqyIVLSGKFGTIGIHNDFEKNDLNEAIGLLKKLGGDELVNKPYRVLSQGQRQLVL 153
Cdd:COG1121 76 RIGYVpqRAEVDWDFPitvrD------VVLMGRYGRRGLFRRPSRADREAVDEALERVGLEDLADRPIGELSGGQQQRVL 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 154 IARALLGKPELLILDEPCNGLDLFSRELLLEQINKLAQlpNHPTLLFVSHYTEEILPIFKNIMLLKQGeIFAQGTRDKIL 233
Cdd:COG1121 150 LARALAQDPDLLLLDEPFAGVDAATEEALYELLRELRR--EGKTILVVTHDLGAVREYFDRVLLLNRG-LVAHGPPEEVL 226
|
250
....*....|....*.
gi 915796356 234 TENVLSKFYPKPIKIF 249
Cdd:COG1121 227 TPENLSRAYGGPVALL 242
|
|
| FepC |
COG1120 |
ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component [Inorganic ion ... |
6-258 |
2.31e-47 |
|
ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component [Inorganic ion transport and metabolism, Coenzyme transport and metabolism];
Pssm-ID: 440737 [Multi-domain] Cd Length: 254 Bit Score: 157.90 E-value: 2.31e-47
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 6 VLSMKNVSFERD-KIILKNINWSLHSGENWVLMGLNGAGKTTLLSLIYGNHWATTGSIEVLGETFGKTNVLALKKRIGLI 84
Cdd:COG1120 1 MLEAENLSVGYGgRPVLDDVSLSLPPGEVTALLGPNGSGKSTLLRALAGLLKPSSGEVLLDGRDLASLSRRELARRIAYV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 85 STAVQSQFP----EhhlaqyIVLSGKFGTIGIHNDFEKNDLNEAIGLLKKLGGDELVNKPYRVLSQGQRQLVLIARALLG 160
Cdd:COG1120 81 PQEPPAPFGltvrE------LVALGRYPHLGLFGRPSAEDREAVEEALERTGLEHLADRPVDELSGGERQRVLIARALAQ 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 161 KPELLILDEPCNGLDLFSRELLLEQINKLAQLPNHpTLLFVSH-------YTEEILpifknimLLKQGEIFAQGTRDKIL 233
Cdd:COG1120 155 EPPLLLLDEPTSHLDLAHQLEVLELLRRLARERGR-TVVMVLHdlnlaarYADRLV-------LLKDGRIVAQGPPEEVL 226
|
250 260
....*....|....*....|....*..
gi 915796356 234 TENVLSKFYPKPIKIF--PVTNNRFAV 258
Cdd:COG1120 227 TPELLEEVYGVEARVIedPVTGRPLVL 253
|
|
| CcmA |
COG1131 |
ABC-type multidrug transport system, ATPase component [Defense mechanisms]; |
7-233 |
2.84e-42 |
|
ABC-type multidrug transport system, ATPase component [Defense mechanisms];
Pssm-ID: 440746 [Multi-domain] Cd Length: 236 Bit Score: 144.05 E-value: 2.84e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 7 LSMKNVSFE-RDKIILKNINWSLHSGENWVLMGLNGAGKTTLLSLIYGNHWATTGSIEVLGETFgKTNVLALKKRIGLIS 85
Cdd:COG1131 1 IEVRGLTKRyGDKTALDGVSLTVEPGEIFGLLGPNGAGKTTTIRMLLGLLRPTSGEVRVLGEDV-ARDPAEVRRRIGYVP 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 86 tavQSQFPEHHL--AQYIVLSGKFgtIGIHNDFEKNDLNEaigLLKKLGGDELVNKPYRVLSQGQRQLVLIARALLGKPE 163
Cdd:COG1131 80 ---QEPALYPDLtvRENLRFFARL--YGLPRKEARERIDE---LLELFGLTDAADRKVGTLSGGMKQRLGLALALLHDPE 151
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 164 LLILDEPCNGLDLFSRELLLEQINKLAQlPNHpTLLFVSHYTEEILPIFKNIMLLKQGEIFAQGTRDKIL 233
Cdd:COG1131 152 LLILDEPTSGLDPEARRELWELLRELAA-EGK-TVLLSTHYLEEAERLCDRVAIIDKGRIVADGTPDELK 219
|
|
| NatA |
COG4555 |
ABC-type Na+ transport system, ATPase component NatA [Energy production and conversion, ... |
6-242 |
1.60e-40 |
|
ABC-type Na+ transport system, ATPase component NatA [Energy production and conversion, Inorganic ion transport and metabolism];
Pssm-ID: 443618 [Multi-domain] Cd Length: 243 Bit Score: 139.99 E-value: 1.60e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 6 VLSMKNVSFE-RDKIILKNINWSLHSGENWVLMGLNGAGKTTLLSLIYGNHWATTGSIEVLGETfGKTNVLALKKRIGLI 84
Cdd:COG4555 1 MIEVENLSKKyGKVPALKDVSFTAKDGEITGLLGPNGAGKTTLLRMLAGLLKPDSGSILIDGED-VRKEPREARRQIGVL 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 85 STAVQsqFPEHHLAQYIVLSgkFGTIgiHNDFEKNDLNEAIGLLKKLGGDELVNKPYRVLSQGQRQLVLIARALLGKPEL 164
Cdd:COG4555 80 PDERG--LYDRLTVRENIRY--FAEL--YGLFDEELKKRIEELIELLGLEEFLDRRVGELSTGMKKKVALARALVHDPKV 153
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 915796356 165 LILDEPCNGLDLFSRELLLEQINKLAQLPNhpTLLFVSHYTEEILPIFKNIMLLKQGEIFAQGTRDKILTENVLSKFY 242
Cdd:COG4555 154 LLLDEPTNGLDVMARRLLREILRALKKEGK--TVLFSSHIMQEVEALCDRVVILHKGKVVAQGSLDELREEIGEENLE 229
|
|
| ABC_Metallic_Cations |
cd03235 |
ATP-binding cassette domain of the metal-type transporters; This family includes transporters ... |
8-227 |
2.43e-40 |
|
ATP-binding cassette domain of the metal-type transporters; This family includes transporters involved in the uptake of various metallic cations such as iron, manganese, and zinc. The ATPases of this group of transporters are very similar to members of iron-siderophore uptake family suggesting that they share a common ancestor. The best characterized metal-type ABC transporters are the YfeABCD system of Y. pestis, the SitABCD system of Salmonella enterica serovar Typhimurium, and the SitABCD transporter of Shigella flexneri. Moreover other uncharacterized homologs of these metal-type transporters are mainly found in pathogens like Haemophilus or enteroinvasive E. coli isolates.
Pssm-ID: 213202 [Multi-domain] Cd Length: 213 Bit Score: 138.44 E-value: 2.43e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 8 SMKNVSFERD-KIILKNINWSLHSGENWVLMGLNGAGKTTLLSLIYGNHWATTGSIEVLGETFGKTNvlalkKRIGLI-- 84
Cdd:cd03235 1 EVEDLTVSYGgHPVLEDVSFEVKPGEFLAIVGPNGAGKSTLLKAILGLLKPTSGSIRVFGKPLEKER-----KRIGYVpq 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 85 STAVQSQFP----EhhlaqyIVLSGKFGTIGIHNDFEKNDLNEAIGLLKKLGGDELVNKPYRVLSQGQRQLVLIARALLG 160
Cdd:cd03235 76 RRSIDRDFPisvrD------VVLMGLYGHKGLFRRLSKADKAKVDEALERVGLSELADRQIGELSGGQQQRVLLARALVQ 149
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 915796356 161 KPELLILDEPCNGLDLFSRELLLEQINKLAQLpNHpTLLFVSHYTEEILPIFKNIMLLKqGEIFAQG 227
Cdd:cd03235 150 DPDLLLLDEPFAGVDPKTQEDIYELLRELRRE-GM-TILVVTHDLGLVLEYFDRVLLLN-RTVVASG 213
|
|
| EcfA2 |
COG1122 |
Energy-coupling factor transporter ATP-binding protein EcfA2 [Inorganic ion transport and ... |
7-235 |
2.52e-40 |
|
Energy-coupling factor transporter ATP-binding protein EcfA2 [Inorganic ion transport and metabolism, General function prediction only];
Pssm-ID: 440739 [Multi-domain] Cd Length: 230 Bit Score: 139.00 E-value: 2.52e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 7 LSMKNVSF--ERDKIILKNINWSLHSGENWVLMGLNGAGKTTLLSLIYGNHWATTGSIEVLGETFGKTNVLALKKRIGLI 84
Cdd:COG1122 1 IELENLSFsyPGGTPALDDVSLSIEKGEFVAIIGPNGSGKSTLLRLLNGLLKPTSGEVLVDGKDITKKNLRELRRKVGLV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 85 StavqsQFPEHHLaqyivlsgkFGTI-------GIHN-DFEKNDLNEAI-GLLKKLGGDELVNKPYRVLSQGQRQLVLIA 155
Cdd:COG1122 81 F-----QNPDDQL---------FAPTveedvafGPENlGLPREEIRERVeEALELVGLEHLADRPPHELSGGQKQRVAIA 146
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 156 RALLGKPELLILDEPCNGLDLFSRELLLEQINKLAQlpNHPTLLFVSHYTEEILPIFKNIMLLKQGEIFAQGTRDKILTE 235
Cdd:COG1122 147 GVLAMEPEVLVLDEPTAGLDPRGRRELLELLKRLNK--EGKTVIIVTHDLDLVAELADRVIVLDDGRIVADGTPREVFSD 224
|
|
| ABC_ATPase |
cd00267 |
ATP-binding cassette transporter nucleotide-binding domain; ABC transporters are a large ... |
8-222 |
1.31e-39 |
|
ATP-binding cassette transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213179 [Multi-domain] Cd Length: 157 Bit Score: 134.68 E-value: 1.31e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 8 SMKNVSFER-DKIILKNINWSLHSGENWVLMGLNGAGKTTLLSLIYGNHWATTGSIEVLGETFGKTNVLALKKRIGLISt 86
Cdd:cd00267 1 EIENLSFRYgGRTALDNVSLTLKAGEIVALVGPNGSGKSTLLRAIAGLLKPTSGEILIDGKDIAKLPLEELRRRIGYVP- 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 87 avqsqfpehhlaQyivlsgkfgtigihndfekndlneaigllkklggdelvnkpyrvLSQGQRQLVLIARALLGKPELLI 166
Cdd:cd00267 80 ------------Q--------------------------------------------LSGGQRQRVALARALLLNPDLLL 103
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 915796356 167 LDEPCNGLDLFSRELLLEQINKLAQlpNHPTLLFVSHYTEEILPIFKNIMLLKQGE 222
Cdd:cd00267 104 LDEPTSGLDPASRERLLELLRELAE--EGRTVIIVTHDPELAELAADRVIVLKDGK 157
|
|
| ABC_Iron-Siderophores_B12_Hemin |
cd03214 |
ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related ... |
8-227 |
2.00e-39 |
|
ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; ABC transporters, involved in the uptake of siderophores, heme, and vitamin B12, are widely conserved in bacteria and archaea. Only very few species lack representatives of the siderophore family transporters. The E. coli BtuCD protein is an ABC transporter mediating vitamin B12 uptake. The two ATP-binding cassettes (BtuD) are in close contact with each other, as are the two membrane-spanning subunits (BtuC); this arrangement is distinct from that observed for the E. coli lipid flippase MsbA. The BtuC subunits provide 20 transmembrane helices grouped around a translocation pathway that is closed to the cytoplasm by a gate region, whereas the dimer arrangement of the BtuD subunits resembles the ATP-bound form of the Rad50 DNA repair enzyme. A prominent cytoplasmic loop of BtuC forms the contact region with the ATP-binding cassette and represent a conserved motif among the ABC transporters.
Pssm-ID: 213181 [Multi-domain] Cd Length: 180 Bit Score: 135.26 E-value: 2.00e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 8 SMKNVSFE-RDKIILKNINWSLHSGENWVLMGLNGAGKTTLLSLIYGNHWATTGSIEVLGETFGKTNVLALKKRIGLIST 86
Cdd:cd03214 1 EVENLSVGyGGRTVLDDLSLSIEAGEIVGILGPNGAGKSTLLKTLAGLLKPSSGEILLDGKDLASLSPKELARKIAYVPQ 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 87 AvqsqfpehhlaqyivlsgkfgtigihndfekndlneaiglLKKLGGDELVNKPYRVLSQGQRQLVLIARALLGKPELLI 166
Cdd:cd03214 81 A----------------------------------------LELLGLAHLADRPFNELSGGERQRVLLARALAQEPPILL 120
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 915796356 167 LDEPCNGLDLFSRELLLEQINKLAQLPNHpTLLFVSHYTEEILPIFKNIMLLKQGEIFAQG 227
Cdd:cd03214 121 LDEPTSHLDIAHQIELLELLRRLARERGK-TVVMVLHDLNLAARYADRVILLKDGRIVAQG 180
|
|
| ABC_DR_subfamily_A |
cd03230 |
ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily ... |
7-223 |
1.21e-38 |
|
ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; This family of ATP-binding proteins belongs to a multi-subunit transporter involved in drug resistance (BcrA and DrrA), nodulation, lipid transport, and lantibiotic immunity. In bacteria and archaea, these transporters usually include an ATP-binding protein and one or two integral membrane proteins. Eukaryotic systems of the ABCA subfamily display ABC domains that are quite similar to this family. The ATP-binding domain shows the highest similarity between all members of the ABC transporter family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213197 [Multi-domain] Cd Length: 173 Bit Score: 132.91 E-value: 1.21e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 7 LSMKNVSFE-RDKIILKNINWSLHSGENWVLMGLNGAGKTTLLSLIYGNHWATTGSIEVLGETFGKtNVLALKKRIGLIs 85
Cdd:cd03230 1 IEVRNLSKRyGKKTALDDISLTVEKGEIYGLLGPNGAGKTTLIKIILGLLKPDSGEIKVLGKDIKK-EPEEVKRRIGYL- 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 86 tavqsqfPEHhlaqyivlsgkfgtigihndfekndlneaIGLLKKLGGDELVNkpyrvLSQGQRQLVLIARALLGKPELL 165
Cdd:cd03230 79 -------PEE-----------------------------PSLYENLTVRENLK-----LSGGMKQRLALAQALLHDPELL 117
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 915796356 166 ILDEPCNGLDLFSRELLLEQINKLAQlpNHPTLLFVSHYTEEILPIFKNIMLLKQGEI 223
Cdd:cd03230 118 ILDEPTSGLDPESRREFWELLRELKK--EGKTILLSSHILEEAERLCDRVAILNNGRI 173
|
|
| ABC_cobalt_CbiO_domain1 |
cd03225 |
First domain of the ATP-binding cassette component of cobalt transport system; Domain I of the ... |
8-222 |
1.22e-36 |
|
First domain of the ATP-binding cassette component of cobalt transport system; Domain I of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota. The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed. This ABC transport system of the CbiMNQO family is involved in cobalt transport in association with the cobalamin (vitamin B12) biosynthetic pathways. Most of cobalt (Cbi) transport systems possess a separate CbiN component, the cobalt-binding periplasmic protein, and they are encoded by the conserved gene cluster cbiMNQO. Both the CbiM and CbiQ proteins are integral cytoplasmic membrane proteins, and the CbiO protein has the linker peptide and the Walker A and B motifs commonly found in the ATPase components of the ABC-type transport systems.
Pssm-ID: 213192 [Multi-domain] Cd Length: 211 Bit Score: 128.74 E-value: 1.22e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 8 SMKNVSF---ERDKIILKNINWSLHSGENWVLMGLNGAGKTTLLSLIYGNHWATTGSIEVLGETFGKTNVLALKKRIGLI 84
Cdd:cd03225 1 ELKNLSFsypDGARPALDDISLTIKKGEFVLIVGPNGSGKSTLLRLLNGLLGPTSGEVLVDGKDLTKLSLKELRRKVGLV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 85 stavqSQFPEHHLAQYIVLSG-KFGTIGIHNDfEKNDLNEAIGLLKKLGGDELVNKPYRVLSQGQRQLVLIARALLGKPE 163
Cdd:cd03225 81 -----FQNPDDQFFGPTVEEEvAFGLENLGLP-EEEIEERVEEALELVGLEGLRDRSPFTLSGGQKQRVAIAGVLAMDPD 154
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 915796356 164 LLILDEPCNGLDLFSRELLLEQINKLAQLPNhpTLLFVSHYTEEILPIFKNIMLLKQGE 222
Cdd:cd03225 155 ILLLDEPTAGLDPAGRRELLELLKKLKAEGK--TIIIVTHDLDLLLELADRVIVLEDGK 211
|
|
| ABC_tran |
pfam00005 |
ABC transporter; ABC transporters for a large family of proteins responsible for translocation ... |
21-172 |
4.80e-36 |
|
ABC transporter; ABC transporters for a large family of proteins responsible for translocation of a variety of compounds across biological membranes. ABC transporters are the largest family of proteins in many completely sequenced bacteria. ABC transporters are composed of two copies of this domain and two copies of a transmembrane domain pfam00664. These four domains may belong to a single polypeptide or belong in different polypeptide chains.
Pssm-ID: 394964 [Multi-domain] Cd Length: 150 Bit Score: 125.45 E-value: 4.80e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 21 LKNINWSLHSGENWVLMGLNGAGKTTLLSLIYGNHWATTGSIEVLGETFGKTNVLALKKRIGLISTAVQsQFPEHHLAQY 100
Cdd:pfam00005 1 LKNVSLTLNPGEILALVGPNGAGKSTLLKLIAGLLSPTEGTILLDGQDLTDDERKSLRKEIGYVFQDPQ-LFPRLTVREN 79
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 915796356 101 IVLSGKFGTIgihndFEKNDLNEAIGLLKKLGG----DELVNKPYRVLSQGQRQLVLIARALLGKPELLILDEPCN 172
Cdd:pfam00005 80 LRLGLLLKGL-----SKREKDARAEEALEKLGLgdlaDRPVGERPGTLSGGQRQRVAIARALLTKPKLLLLDEPTA 150
|
|
| PhnC |
COG3638 |
ABC-type phosphate/phosphonate transport system, ATPase component [Inorganic ion transport and ... |
5-242 |
1.22e-33 |
|
ABC-type phosphate/phosphonate transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 442855 [Multi-domain] Cd Length: 249 Bit Score: 122.09 E-value: 1.22e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 5 AVLSMKNVS--FERDKIILKNINWSLHSGENWVLMGLNGAGKTTLLSLIYGNHWATTGSIEVLGETFGKTN---VLALKK 79
Cdd:COG3638 1 PMLELRNLSkrYPGGTPALDDVSLEIERGEFVALIGPSGAGKSTLLRCLNGLVEPTSGEILVDGQDVTALRgraLRRLRR 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 80 RIGLIstavqsqFPEHHLaqyI--------VLSGKFGTIG----IHNDFEKNDLNEAIGLLKKLGGDELVNKPYRVLSQG 147
Cdd:COG3638 81 RIGMI-------FQQFNL---VprlsvltnVLAGRLGRTStwrsLLGLFPPEDRERALEALERVGLADKAYQRADQLSGG 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 148 QRQLVLIARALLGKPELLILDEPCNGLD-LFSREL--LLEQINKLAQLpnhpTLLFVSHYTEEILPIFKNIMLLKQGEIF 224
Cdd:COG3638 151 QQQRVAIARALVQEPKLILADEPVASLDpKTARQVmdLLRRIAREDGI----TVVVNLHQVDLARRYADRIIGLRDGRVV 226
|
250
....*....|....*...
gi 915796356 225 AQGTRDKiLTENVLSKFY 242
Cdd:COG3638 227 FDGPPAE-LTDAVLREIY 243
|
|
| PRK10938 |
PRK10938 |
putative molybdenum transport ATP-binding protein ModF; Provisional |
17-207 |
2.11e-33 |
|
putative molybdenum transport ATP-binding protein ModF; Provisional
Pssm-ID: 182852 [Multi-domain] Cd Length: 490 Bit Score: 126.28 E-value: 2.11e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 17 DKIILKNINWSLHSGENWVLMGLNGAGKTTLLSLI-------YGNHWATTGSIEVLGETfgktnVLALKKRIGLISTAVQ 89
Cdd:PRK10938 272 DRPILHNLSWQVNPGEHWQIVGPNGAGKSTLLSLItgdhpqgYSNDLTLFGRRRGSGET-----IWDIKKHIGYVSSSLH 346
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 90 SQFPEHHLAQYIVLSGKFGTIGIHNDFEKNDLNEAIGLLKKLG-GDELVNKPYRVLSQGQRQLVLIARALLGKPELLILD 168
Cdd:PRK10938 347 LDYRVSTSVRNVILSGFFDSIGIYQAVSDRQQKLAQQWLDILGiDKRTADAPFHSLSWGQQRLALIVRALVKHPTLLILD 426
|
170 180 190 200
....*....|....*....|....*....|....*....|
gi 915796356 169 EPCNGLDLFSRELLLEQINKLaqLPNHPT-LLFVSHYTEE 207
Cdd:PRK10938 427 EPLQGLDPLNRQLVRRFVDVL--ISEGETqLLFVSHHAED 464
|
|
| ABC_PhnC_transporter |
cd03256 |
ATP-binding cassette domain of the binding protein-dependent phosphonate transport system; ... |
12-242 |
2.55e-33 |
|
ATP-binding cassette domain of the binding protein-dependent phosphonate transport system; Phosphonates are a class of organophosphorus compounds characterized by a chemically stable carbon-to-phosphorus (C-P) bond. Phosphonates are widespread among naturally occurring compounds in all kingdoms of wildlife, but only prokaryotic microorganisms are able to cleave this bond. Certain bacteria such as E. coli can use alkylphosphonates as a phosphorus source. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213223 [Multi-domain] Cd Length: 241 Bit Score: 121.14 E-value: 2.55e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 12 VSFERDKIILKNINWSLHSGENWVLMGLNGAGKTTLLSLIYGNHWATTGSIEVLGE---TFGKTNVLALKKRIGLIstav 88
Cdd:cd03256 8 KTYPNGKKALKDVSLSINPGEFVALIGPSGAGKSTLLRCLNGLVEPTSGSVLIDGTdinKLKGKALRQLRRQIGMI---- 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 89 qsqFPEHHLAQYI-----VLSGKFGTI----GIHNDFEKNDLNEAIGLLKKLGGDELVNKPYRVLSQGQRQLVLIARALL 159
Cdd:cd03256 84 ---FQQFNLIERLsvlenVLSGRLGRRstwrSLFGLFPKEEKQRALAALERVGLLDKAYQRADQLSGGQQQRVAIARALM 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 160 GKPELLILDEPCNGLD-LFSREL--LLEQINKLAQLpnhpTLLFVSHYTEEILPIFKNIMLLKQGEIFAQGTRDKiLTEN 236
Cdd:cd03256 161 QQPKLILADEPVASLDpASSRQVmdLLKRINREEGI----TVIVSLHQVDLAREYADRIVGLKDGRIVFDGPPAE-LTDE 235
|
....*.
gi 915796356 237 VLSKFY 242
Cdd:cd03256 236 VLDEIY 241
|
|
| ABC_MJ0796_LolCDE_FtsE |
cd03255 |
ATP-binding cassette domain of the transporters involved in export of lipoprotein and ... |
7-223 |
2.62e-31 |
|
ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and Cell division ATP-binding protein FtsE; This family is comprised of MJ0796 ATP-binding cassette, macrolide-specific ABC-type efflux carrier (MacAB), and proteins involved in cell division (FtsE), and release of lipoproteins from the cytoplasmic membrane (LolCDE). They are clustered together phylogenetically. MacAB is an exporter that confers resistance to macrolides, while the LolCDE system is not a transporter at all. The FtsEX complex resembles an ABC transporter, where FtsE is the ATPase and the membrane subunit FtsX resembles a permease subunit. But rather than transporting any substrate, the complex acts in cell division by undergoing conformational changes that alter the activity of cell wall hydrolases located outside the plasma membrane. The complex is widely conserved in bacteria, but also extremely divergent in sequence between different lineages. The LolCDE complex catalyzes the release of lipoproteins from the cytoplasmic membrane prior to their targeting to the outer membrane.
Pssm-ID: 213222 [Multi-domain] Cd Length: 218 Bit Score: 115.28 E-value: 2.62e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 7 LSMKNVSF-----ERDKIILKNINWSLHSGENWVLMGLNGAGKTTLLSLIYGNHWATTGSIEVLGETFGKTNVLAL---- 77
Cdd:cd03255 1 IELKNLSKtygggGEKVQALKGVSLSIEKGEFVAIVGPSGSGKSTLLNILGGLDRPTSGEVRVDGTDISKLSEKELaafr 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 78 KKRIGLIstavqsqFPEHHLAQYI----------VLSGKFGtigihndfeKNDLNEAIGLLKKLGGDELVNKPYRVLSQG 147
Cdd:cd03255 81 RRHIGFV-------FQSFNLLPDLtalenvelplLLAGVPK---------KERRERAEELLERVGLGDRLNHYPSELSGG 144
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 915796356 148 QRQLVLIARALLGKPELLILDEPCNGLDLFSRELLLEQINKLAQLPNHpTLLFVSHyTEEILPIFKNIMLLKQGEI 223
Cdd:cd03255 145 QQQRVAIARALANDPKIILADEPTGNLDSETGKEVMELLRELNKEAGT-TIVVVTH-DPELAEYADRIIELRDGKI 218
|
|
| CcmA |
COG4133 |
ABC-type transport system involved in cytochrome c biogenesis, ATPase component ... |
5-210 |
1.03e-30 |
|
ABC-type transport system involved in cytochrome c biogenesis, ATPase component [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 443308 [Multi-domain] Cd Length: 206 Bit Score: 113.34 E-value: 1.03e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 5 AVLSMKNVSFER-DKIILKNINWSLHSGENWVLMGLNGAGKTTLLSLIYGNHWATTGSIEVLGETFGKtNVLALKKRIGL 83
Cdd:COG4133 1 MMLEAENLSCRRgERLLFSGLSFTLAAGEALALTGPNGSGKTTLLRILAGLLPPSAGEVLWNGEPIRD-AREDYRRRLAY 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 84 IS--TAVQSQF-PEHHLAQYIVLSGKFGTigihndfeKNDLNEAiglLKKLGGDELVNKPYRVLSQGQRQLVLIARALLG 160
Cdd:COG4133 80 LGhaDGLKPELtVRENLRFWAALYGLRAD--------REAIDEA---LEAVGLAGLADLPVRQLSAGQKRRVALARLLLS 148
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 915796356 161 KPELLILDEPCNGLDLFSRELLLEQINKLAQlpNHPTLLFVSHYTEEILP 210
Cdd:COG4133 149 PAPLWLLDEPFTALDAAGVALLAELIAAHLA--RGGAVLLTTHQPLELAA 196
|
|
| GsiA |
COG1123 |
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain ... |
1-234 |
5.88e-30 |
|
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 440740 [Multi-domain] Cd Length: 514 Bit Score: 117.31 E-value: 5.88e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 1 MTnnAVLSMKNVSFE---RDKIILKNINWSLHSGENWVLMGLNGAGKTTLLSLIYG---NHWATTGSIEVLGETFGKTNV 74
Cdd:COG1123 1 MT--PLLEVRDLSVRypgGDVPAVDGVSLTIAPGETVALVGESGSGKSTLALALMGllpHGGRISGEVLLDGRDLLELSE 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 75 LALKKRIGLIStavqsQFPEHHLAQYIVLSGKFGTIGIHNDFEKNDLNEAIGLLKKLGGDELVNKPYRVLSQGQRQLVLI 154
Cdd:COG1123 79 ALRGRRIGMVF-----QDPMTQLNPVTVGDQIAEALENLGLSRAEARARVLELLEAVGLERRLDRYPHQLSGGQRQRVAI 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 155 ARALLGKPELLILDEPCNGLDLFSRELLLEQINKLAQLPNHpTLLFVSHYTEEILPIFKNIMLLKQGEIFAQGTRDKILT 234
Cdd:COG1123 154 AMALALDPDLLIADEPTTALDVTTQAEILDLLRELQRERGT-TVLLITHDLGVVAEIADRVVVMDDGRIVEDGPPEEILA 232
|
|
| GsiA |
COG1123 |
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain ... |
6-234 |
4.72e-29 |
|
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 440740 [Multi-domain] Cd Length: 514 Bit Score: 114.62 E-value: 4.72e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 6 VLSMKNVSFE------RDKIILKNINWSLHSGENWVLMGLNGAGKTTLLSLIYGNHWATTGSIEVLGE---TFGKTNVLA 76
Cdd:COG1123 260 LLEVRNLSKRypvrgkGGVRAVDDVSLTLRRGETLGLVGESGSGKSTLARLLLGLLRPTSGSILFDGKdltKLSRRSLRE 339
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 77 LKKRIGLIStavqsQFPEHHLAQYIvlsgkfgTIG--------IHNDFEKNDLNEAIG-LLKKLG-GDELVNKPYRVLSQ 146
Cdd:COG1123 340 LRRRVQMVF-----QDPYSSLNPRM-------TVGdiiaeplrLHGLLSRAERRERVAeLLERVGlPPDLADRYPHELSG 407
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 147 GQRQLVLIARALLGKPELLILDEPCNGLDLFSRELLLEQINKLAQLPNHpTLLFVSH-------YTEEilpifknIMLLK 219
Cdd:COG1123 408 GQRQRVAIARALALEPKLLILDEPTSALDVSVQAQILNLLRDLQRELGL-TYLFISHdlavvryIADR-------VAVMY 479
|
250
....*....|....*
gi 915796356 220 QGEIFAQGTRDKILT 234
Cdd:COG1123 480 DGRIVEDGPTEEVFA 494
|
|
| LolD |
COG1136 |
ABC-type lipoprotein export system, ATPase component [Cell wall/membrane/envelope biogenesis]; |
4-226 |
8.75e-29 |
|
ABC-type lipoprotein export system, ATPase component [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440751 [Multi-domain] Cd Length: 227 Bit Score: 108.98 E-value: 8.75e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 4 NAVLSMKNVSF-----ERDKIILKNINWSLHSGENWVLMGLNGAGKTTLLSLIYGNHWATTGSIEVLGetfgkTNVLALK 78
Cdd:COG1136 2 SPLLELRNLTKsygtgEGEVTALRGVSLSIEAGEFVAIVGPSGSGKSTLLNILGGLDRPTSGEVLIDG-----QDISSLS 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 79 ---------KRIGLIstavqsqFPEHHLAQY------IVLSGKFGtiGIHndfEKNDLNEAIGLLKKLG-GDELVNKPYR 142
Cdd:COG1136 77 erelarlrrRHIGFV-------FQFFNLLPEltalenVALPLLLA--GVS---RKERRERARELLERVGlGDRLDHRPSQ 144
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 143 vLSQGQRQLVLIARALLGKPELLILDEPCNGLDLFSRELLLEQINKLAQLPNHpTLLFVSHyTEEILPIFKNIMLLKQGE 222
Cdd:COG1136 145 -LSGGQQQRVAIARALVNRPKLILADEPTGNLDSKTGEEVLELLRELNRELGT-TIVMVTH-DPELAARADRVIRLRDGR 221
|
....
gi 915796356 223 IFAQ 226
Cdd:COG1136 222 IVSD 225
|
|
| anch_rpt_ABC |
TIGR03771 |
anchored repeat-type ABC transporter, ATP-binding subunit; This protein family is the ... |
27-233 |
1.89e-28 |
|
anchored repeat-type ABC transporter, ATP-binding subunit; This protein family is the ATP-binding cassette subunit of binding protein-dependent ABC transporter complex that strictly co-occurs with TIGR03769. TIGRFAMs model TIGR03769 describes a protein domain that occurs singly or as one of up to three repeats in proteins of a number of Actinobacteria, including Propionibacterium acnes KPA171202. The TIGR03769 domain occurs both in an adjacent gene for the substrate-binding protein and in additional (often nearby) proteins, often with LPXTG-like sortase recognition signals. Homologous ATP-binding subunits outside the scope of this family include manganese transporter MntA in Synechocystis sp. PCC 6803 and chelated iron transporter subunits. The function of this transporter complex is unknown. [Transport and binding proteins, Unknown substrate]
Pssm-ID: 163483 [Multi-domain] Cd Length: 223 Bit Score: 108.01 E-value: 1.89e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 27 SLHSGENWVLMGLNGAGKTTLLSLIYGNHWATTGSIEVLGETFGKTnvlalKKRIGLIstavqsqfPEHHL--------A 98
Cdd:TIGR03771 2 SADKGELLGLLGPNGAGKTTLLRAILGLIPPAKGTVKVAGASPGKG-----WRHIGYV--------PQRHEfawdfpisV 68
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 99 QYIVLSGKFGTIGIHNDFEKNDLNEAIGLLKKLGGDELVNKPYRVLSQGQRQLVLIARALLGKPELLILDEPCNGLDLFS 178
Cdd:TIGR03771 69 AHTVMSGRTGHIGWLRRPCVADFAAVRDALRRVGLTELADRPVGELSGGQRQRVLVARALATRPSVLLLDEPFTGLDMPT 148
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 915796356 179 RELLLEQINKLAQLPNhpTLLFVSHYTEEILPIFKNIMLLkQGEIFAQGTRDKIL 233
Cdd:TIGR03771 149 QELLTELFIELAGAGT--AILMTTHDLAQAMATCDRVVLL-NGRVIADGTPQQLQ 200
|
|
| Uup |
COG0488 |
ATPase components of ABC transporters with duplicated ATPase domains [General function ... |
9-203 |
5.55e-28 |
|
ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only];
Pssm-ID: 440254 [Multi-domain] Cd Length: 520 Bit Score: 111.70 E-value: 5.55e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 9 MKNVSFER-DKIILKNINWSLHSGENWVLMGLNGAGKTTLLSLIYGNHWATTGSIE---------------------VLG 66
Cdd:COG0488 1 LENLSKSFgGRPLLDDVSLSINPGDRIGLVGRNGAGKSTLLKILAGELEPDSGEVSipkglrigylpqeppldddltVLD 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 67 ETF-GKTNVLALKKRIGLISTAVQsqFPEHHLAQYIVLSGKFGTIGIHnDFEkndlNEAIGLLKKLG-GDELVNKPYRVL 144
Cdd:COG0488 81 TVLdGDAELRALEAELEELEAKLA--EPDEDLERLAELQEEFEALGGW-EAE----ARAEEILSGLGfPEEDLDRPVSEL 153
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 915796356 145 SQGQRQLVLIARALLGKPELLILDEPCNGLDLFSRElLLEQInkLAQLPNhpTLLFVSH 203
Cdd:COG0488 154 SGGWRRRVALARALLSEPDLLLLDEPTNHLDLESIE-WLEEF--LKNYPG--TVLVVSH 207
|
|
| ABC_cobalt_CbiO_domain2 |
cd03226 |
Second domain of the ATP-binding cassette component of cobalt transport system; Domain II of ... |
11-223 |
2.12e-27 |
|
Second domain of the ATP-binding cassette component of cobalt transport system; Domain II of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota. The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed. The CbiMNQO family ABC transport system is involved in cobalt transport in association with the cobalamin (vitamin B12) biosynthetic pathways. Most cobalt (Cbi) transport systems possess a separate CbiN component, the cobalt-binding periplasmic protein, and they are encoded by the conserved gene cluster cbiMNQO. Both the CbiM and CbiQ proteins are integral cytoplasmic membrane proteins, and the CbiO protein has the linker peptide and the Walker A and B motifs commonly found in the ATPase components of the ABC-type transport systems.
Pssm-ID: 213193 [Multi-domain] Cd Length: 205 Bit Score: 104.65 E-value: 2.12e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 11 NVSFERDKIILKNINWSLHSGENWVLMGLNGAGKTTLLSLIYGNHWATTGSIEVLGEtfgKTNVLALKKRIGLISTAVQS 90
Cdd:cd03226 6 SFSYKKGTEILDDLSLDLYAGEIIALTGKNGAGKTTLAKILAGLIKESSGSILLNGK---PIKAKERRKSIGYVMQDVDY 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 91 QFPEHHLAQYIVLSGKfgtiGIHNDFEKndlneAIGLLKKLGGDELVNKPYRVLSQGQRQLVLIARALLGKPELLILDEP 170
Cdd:cd03226 83 QLFTDSVREELLLGLK----ELDAGNEQ-----AETVLKDLDLYALKERHPLSLSGGQKQRLAIAAALLSGKDLLIFDEP 153
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 915796356 171 CNGLDLFSRELLLEQINKLAQLPNhpTLLFVSHYTEEILPIFKNIMLLKQGEI 223
Cdd:cd03226 154 TSGLDYKNMERVGELIRELAAQGK--AVIVITHDYEFLAKVCDRVLLLANGAI 204
|
|
| ABC_NatA_sodium_exporter |
cd03266 |
ATP-binding cassette domain of the Na+ transporter; NatA is the ATPase component of a ... |
31-227 |
2.15e-27 |
|
ATP-binding cassette domain of the Na+ transporter; NatA is the ATPase component of a bacterial ABC-type Na+ transport system called NatAB, which catalyzes ATP-dependent electrogenic Na+ extrusion without mechanically coupled proton or K+ uptake. NatB possess six putative membrane spanning regions at its C-terminus. In B. subtilis, NatAB is inducible by agents such as ethanol and protonophores, which lower the proton-motive force across the membrane. The closest sequence similarity to NatA is exhibited by DrrA of the two-component daunorubicin- and doxorubicin-efflux system. Hence, the functional NatAB is presumably assembled with two copies of a single ATP-binding protein and a single integral membrane protein.
Pssm-ID: 213233 [Multi-domain] Cd Length: 218 Bit Score: 105.14 E-value: 2.15e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 31 GENWVLMGLNGAGKTTLLSLIYGNHWATTGSIEVLGETFGKtNVLALKKRIGLISTAvqsqfpehhLAQYIVLSGK---- 106
Cdd:cd03266 31 GEVTGLLGPNGAGKTTTLRMLAGLLEPDAGFATVDGFDVVK-EPAEARRRLGFVSDS---------TGLYDRLTARenle 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 107 -FGTI-GIHNDFEKNDLNEaigLLKKLGGDELVNKPYRVLSQGQRQLVLIARALLGKPELLILDEPCNGLDLFSRELLLE 184
Cdd:cd03266 101 yFAGLyGLKGDELTARLEE---LADRLGMEELLDRRVGGFSTGMRQKVAIARALVHDPPVLLLDEPTTGLDVMATRALRE 177
|
170 180 190 200
....*....|....*....|....*....|....*....|...
gi 915796356 185 QINKLAQLPNhpTLLFVSHYTEEILPIFKNIMLLKQGEIFAQG 227
Cdd:cd03266 178 FIRQLRALGK--CILFSTHIMQEVERLCDRVVVLHRGRVVYEG 218
|
|
| SunT |
COG2274 |
ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase ... |
7-233 |
2.60e-27 |
|
ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain [Defense mechanisms];
Pssm-ID: 441875 [Multi-domain] Cd Length: 711 Bit Score: 110.31 E-value: 2.60e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 7 LSMKNVSF---ERDKIILKNINWSLHSGENWVLMGLNGAGKTTLLSLIYGNHWATTGSIEVLGETFGKTNVLALKKRIGL 83
Cdd:COG2274 474 IELENVSFrypGDSPPVLDNISLTIKPGERVAIVGRSGSGKSTLLKLLLGLYEPTSGRILIDGIDLRQIDPASLRRQIGV 553
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 84 IStavqsqfpehhlaQYIVLsgkF-GTIgIHN------DFEKNDLNEAiglLKKLGGDELVNK-P--Y--------RVLS 145
Cdd:COG2274 554 VL-------------QDVFL---FsGTI-RENitlgdpDATDEEIIEA---ARLAGLHDFIEAlPmgYdtvvgeggSNLS 613
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 146 QGQRQLVLIARALLGKPELLILDEPCNGLDLFSRELLLEQINKLAQlpnHPTLLFVSHYteeiLPIFKN---IMLLKQGE 222
Cdd:COG2274 614 GGQRQRLAIARALLRNPRILILDEATSALDAETEAIILENLRRLLK---GRTVIIIAHR----LSTIRLadrIIVLDKGR 686
|
250
....*....|.
gi 915796356 223 IFAQGTRDKIL 233
Cdd:COG2274 687 IVEDGTHEELL 697
|
|
| ABC_NikE_OppD_transporters |
cd03257 |
ATP-binding cassette domain of nickel/oligopeptides specific transporters; The ABC transporter ... |
6-227 |
8.37e-27 |
|
ATP-binding cassette domain of nickel/oligopeptides specific transporters; The ABC transporter subfamily specific for the transport of dipeptides, oligopeptides (OppD), and nickel (NikDE). The NikABCDE system of E. coli belongs to this family and is composed of the periplasmic binding protein NikA, two integral membrane components (NikB and NikC), and two ATPase (NikD and NikE). The NikABCDE transporter is synthesized under anaerobic conditions to meet the increased demand for nickel resulting from hydrogenase synthesis. The molecular mechanism of nickel uptake in many bacteria and most archaea is not known. Many other members of this ABC family are also involved in the uptake of dipeptides and oligopeptides. The oligopeptide transport system (Opp) is a five-component ABC transport composed of a membrane-anchored substrate binding proteins (SRP), OppA, two transmembrane proteins, OppB and OppC, and two ATP-binding domains, OppD and OppF.
Pssm-ID: 213224 [Multi-domain] Cd Length: 228 Bit Score: 103.74 E-value: 8.37e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 6 VLSMKN--VSFERDKI---ILKNINWSLHSGENWVLMGLNGAGKTTLLSLIYGNHWATTGSIEVLGE---TFGKTNVLAL 77
Cdd:cd03257 1 LLEVKNlsVSFPTGGGsvkALDDVSFSIKKGETLGLVGESGSGKSTLARAILGLLKPTSGSIIFDGKdllKLSRRLRKIR 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 78 KKRIGLISTAVQSQFP-----EHHLAQyivlsgkfgTIGIHNDFEKNDLNEAIG--LLKKLGGDELV--NKPYRvLSQGQ 148
Cdd:cd03257 81 RKEIQMVFQDPMSSLNprmtiGEQIAE---------PLRIHGKLSKKEARKEAVllLLVGVGLPEEVlnRYPHE-LSGGQ 150
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 915796356 149 RQLVLIARALLGKPELLILDEPCNGLDLFSRELLLEQINKLAQLPNHpTLLFVSHYTEEILPIFKNIMLLKQGEIFAQG 227
Cdd:cd03257 151 RQRVAIARALALNPKLLIADEPTSALDVSVQAQILDLLKKLQEELGL-TLLFITHDLGVVAKIADRVAVMYAGKIVEEG 228
|
|
| ABCC_MRP_Like |
cd03228 |
ATP-binding cassette domain of multidrug resistance protein-like transporters; The MRP ... |
7-203 |
1.53e-26 |
|
ATP-binding cassette domain of multidrug resistance protein-like transporters; The MRP (Multidrug Resistance Protein)-like transporters are involved in drug, peptide, and lipid export. They belong to the subfamily C of the ATP-binding cassette (ABC) superfamily of transport proteins. The ABCC subfamily contains transporters with a diverse functional spectrum that includes ion transport, cell surface receptor, and toxin secretion activities. The MRP-like family, similar to all ABC proteins, have a common four-domain core structure constituted by two membrane-spanning domains, each composed of six transmembrane (TM) helices, and two nucleotide-binding domains (NBD). ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213195 [Multi-domain] Cd Length: 171 Bit Score: 101.31 E-value: 1.53e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 7 LSMKNVSF---ERDKIILKNINWSLHSGENWVLMGLNGAGKTTLLSLIYGNHWATTGSIEVLGETFGKTNVLALKKRIGL 83
Cdd:cd03228 1 IEFKNVSFsypGRPKPVLKDVSLTIKPGEKVAIVGPSGSGKSTLLKLLLRLYDPTSGEILIDGVDLRDLDLESLRKNIAY 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 84 IStavqsQFPehHLaqyivlsgkF-GTIgihndfEKNdlneaigllkklggdelvnkpyrVLSQGQRQLVLIARALLGKP 162
Cdd:cd03228 81 VP-----QDP--FL---------FsGTI------REN-----------------------ILSGGQRQRIAIARALLRDP 115
|
170 180 190 200
....*....|....*....|....*....|....*....|.
gi 915796356 163 ELLILDEPCNGLDLFSRELLLEQINKLAQlpnHPTLLFVSH 203
Cdd:cd03228 116 PILILDEATSALDPETEALILEALRALAK---GKTVIVIAH 153
|
|
| CydD |
COG4988 |
ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease ... |
2-236 |
2.20e-26 |
|
ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 444012 [Multi-domain] Cd Length: 563 Bit Score: 107.15 E-value: 2.20e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 2 TNNAVLSMKNVSF--ERDKIILKNINWSLHSGENWVLMGLNGAGKTTLLSLIYGNHWATTGSIEVLGETFGKTNVLALKK 79
Cdd:COG4988 332 AGPPSIELEDVSFsyPGGRPALDGLSLTIPPGERVALVGPSGAGKSTLLNLLLGFLPPYSGSILINGVDLSDLDPASWRR 411
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 80 RIGLIStavqsQFPehHLAQyivlsgkfGTI------GiHNDFEKNDLNEAiglLKKLGGDELVNK-P----YRV----- 143
Cdd:COG4988 412 QIAWVP-----QNP--YLFA--------GTIrenlrlG-RPDASDEELEAA---LEAAGLDEFVAAlPdgldTPLgeggr 472
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 144 -LSQGQRQLVLIARALLGKPELLILDEPCNGLDLFSRELLLEQINKLAQlpnHPTLLFVSHyTEEILPIFKNIMLLKQGE 222
Cdd:COG4988 473 gLSGGQAQRLALARALLRDAPLLLLDEPTAHLDAETEAEILQALRRLAK---GRTVILITH-RLALLAQADRILVLDDGR 548
|
250
....*....|....
gi 915796356 223 IFAQGTRDKILTEN 236
Cdd:COG4988 549 IVEQGTHEELLAKN 562
|
|
| ABC_Class3 |
cd03229 |
ATP-binding cassette domain of the binding protein-dependent transport systems; This class is ... |
7-222 |
2.84e-26 |
|
ATP-binding cassette domain of the binding protein-dependent transport systems; This class is comprised of all BPD (Binding Protein Dependent) systems that are largely represented in archaea and eubacteria and are primarily involved in scavenging solutes from the environment. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213196 [Multi-domain] Cd Length: 178 Bit Score: 101.11 E-value: 2.84e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 7 LSMKNVSFER-DKIILKNINWSLHSGENWVLMGLNGAGKTTLLSLIYGNHWATTGSIEVLGETFGKTN--VLALKKRIGL 83
Cdd:cd03229 1 LELKNVSKRYgQKTVLNDVSLNIEAGEIVALLGPSGSGKSTLLRCIAGLEEPDSGSILIDGEDLTDLEdeLPPLRRRIGM 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 84 IstavqsqfpehhLAQYIVLSgkfgtigiHNDFEKNdlneaIGLLkklggdelvnkpyrvLSQGQRQLVLIARALLGKPE 163
Cdd:cd03229 81 V------------FQDFALFP--------HLTVLEN-----IALG---------------LSGGQQQRVALARALAMDPD 120
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 915796356 164 LLILDEPCNGLDLFSRELLLEQINKLAQLPNHpTLLFVSHYTEEILPIFKNIMLLKQGE 222
Cdd:cd03229 121 VLLLDEPTSALDPITRREVRALLKSLQAQLGI-TVVLVTHDLDEAARLADRVVVLRDGK 178
|
|
| ABC_OpuCA_Osmoprotection |
cd03295 |
ATP-binding cassette domain of the osmoprotectant transporter; OpuCA is a the ATP binding ... |
7-234 |
3.19e-26 |
|
ATP-binding cassette domain of the osmoprotectant transporter; OpuCA is a the ATP binding component of a bacterial solute transporter that serves a protective role to cells growing in a hyperosmolar environment. ABC (ATP-binding cassette) transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition, to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213262 [Multi-domain] Cd Length: 242 Bit Score: 102.38 E-value: 3.19e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 7 LSMKNVS--FERDKIILKNINWSLHSGENWVLMGLNGAGKTTLLSLIYGNHWATTGSIEVLGETFGKTNVLALKKRIGLi 84
Cdd:cd03295 1 IEFENVTkrYGGGKKAVNNLNLEIAKGEFLVLIGPSGSGKTTTMKMINRLIEPTSGEIFIDGEDIREQDPVELRRKIGY- 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 85 stAVQS--QFPEHHLAQYIVLSGKFgtigIHNDFEKND--LNEAIGLLKkLGGDELVNKPYRVLSQGQRQLVLIARALLG 160
Cdd:cd03295 80 --VIQQigLFPHMTVEENIALVPKL----LKWPKEKIRerADELLALVG-LDPAEFADRYPHELSGGQQQRVGVARALAA 152
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 915796356 161 KPELLILDEPCNGLDLFSRELLLEQINKLAQLPnHPTLLFVSHYTEEILPIFKNIMLLKQGEIFAQGTRDKILT 234
Cdd:cd03295 153 DPPLLLMDEPFGALDPITRDQLQEEFKRLQQEL-GKTIVFVTHDIDEAFRLADRIAIMKNGEIVQVGTPDEILR 225
|
|
| ABC_drug_resistance_like |
cd03264 |
ABC-type multidrug transport system, ATPase component; The biological function of this family ... |
7-227 |
3.31e-26 |
|
ABC-type multidrug transport system, ATPase component; The biological function of this family is not well characterized, but display ABC domains similar to members of ABCA subfamily. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213231 [Multi-domain] Cd Length: 211 Bit Score: 101.50 E-value: 3.31e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 7 LSMKNVSFE-RDKIILKNINWSLHSGEnWVLMGLNGAGKTTLLSLIYGNHWATTGSIEVLGETFGKtNVLALKKRIGLIS 85
Cdd:cd03264 1 LQLENLTKRyGKKRALDGVSLTLGPGM-YGLLGPNGAGKTTLMRILATLTPPSSGTIRIDGQDVLK-QPQKLRRRIGYLP 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 86 T--AVQSQFP-EHHLAQYIVLSGkfgtigIHNDFEKNdlnEAIGLLKKLGGDELVNKPYRVLSQGQRQLVLIARALLGKP 162
Cdd:cd03264 79 QefGVYPNFTvREFLDYIAWLKG------IPSKEVKA---RVDEVLELVNLGDRAKKKIGSLSGGMRRRVGIAQALVGDP 149
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 915796356 163 ELLILDEPCNGLDLFSRELLLeqiNKLAQLPNHPTLLFVSHYTEEILPIFKNIMLLKQGEIFAQG 227
Cdd:cd03264 150 SILIVDEPTAGLDPEERIRFR---NLLSELGEDRIVILSTHIVEDVESLCNQVAVLNKGKLVFEG 211
|
|
| FtsE |
COG2884 |
Cell division ATPase FtsE [Cell cycle control, cell division, chromosome partitioning]; |
6-229 |
4.68e-26 |
|
Cell division ATPase FtsE [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 442130 [Multi-domain] Cd Length: 223 Bit Score: 101.67 E-value: 4.68e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 6 VLSMKNVS--FERDKIILKNINWSLHSGEnWV-LMGLNGAGKTTLLSLIYGNHWATTGSIEVLGE---TFGKTNVLALKK 79
Cdd:COG2884 1 MIRFENVSkrYPGGREALSDVSLEIEKGE-FVfLTGPSGAGKSTLLKLLYGEERPTSGQVLVNGQdlsRLKRREIPYLRR 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 80 RIGLIstavqsqFPEHHLaqyivLSGKfgT-----------IGIHNDFEKNDLNEAiglLKKLGGDELVNKPYRVLSQGQ 148
Cdd:COG2884 80 RIGVV-------FQDFRL-----LPDR--TvyenvalplrvTGKSRKEIRRRVREV---LDLVGLSDKAKALPHELSGGE 142
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 149 RQLVLIARALLGKPELLILDEPCNGLD-LFSREL--LLEQINKLAQlpnhpTLLFVSHYTEEILPIFKNIMLLKQGEIFA 225
Cdd:COG2884 143 QQRVAIARALVNRPELLLADEPTGNLDpETSWEImeLLEEINRRGT-----TVLIATHDLELVDRMPKRVLELEDGRLVR 217
|
....
gi 915796356 226 QGTR 229
Cdd:COG2884 218 DEAR 221
|
|
| ABC_Carb_Monos_I |
cd03216 |
First domain of the ATP-binding cassette component of monosaccharide transport system; This ... |
7-226 |
5.33e-26 |
|
First domain of the ATP-binding cassette component of monosaccharide transport system; This family represents the domain I of the carbohydrate uptake proteins that transport only monosaccharides (Monos). The Carb_Monos family is involved in the uptake of monosaccharides, such as pentoses (such as xylose, arabinose, and ribose) and hexoses (such as xylose, arabinose, and ribose), that cannot be broken down to simple sugars by hydrolysis. Pentoses include xylose, arabinose, and ribose. Important hexoses include glucose, galactose, and fructose. In members of the Carb_monos family, the single hydrophobic gene product forms a homodimer while the ABC protein represents a fusion of two nucleotide-binding domains. However, it is assumed that two copies of the ABC domains are present in the assembled transporter.
Pssm-ID: 213183 [Multi-domain] Cd Length: 163 Bit Score: 99.81 E-value: 5.33e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 7 LSMKNV--SFErDKIILKNINWSLHSGENWVLMGLNGAGKTTLLSLIYGNHWATTGSIEVLGETFGKTNVL-ALKKRIGL 83
Cdd:cd03216 1 LELRGItkRFG-GVKALDGVSLSVRRGEVHALLGENGAGKSTLMKILSGLYKPDSGEILVDGKEVSFASPRdARRAGIAM 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 84 IStavqsqfpehhlaQyivlsgkfgtigihndfekndlneaigllkklggdelvnkpyrvLSQGQRQLVLIARALLGKPE 163
Cdd:cd03216 80 VY-------------Q--------------------------------------------LSVGERQMVEIARALARNAR 102
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 915796356 164 LLILDEPCNGLDLFSRELLLEQINKLAQlpNHPTLLFVSHYTEEILPIFKNIMLLKQGEIFAQ 226
Cdd:cd03216 103 LLILDEPTAALTPAEVERLFKVIRRLRA--QGVAVIFISHRLDEVFEIADRVTVLRDGRVVGT 163
|
|
| ABC_ModC_molybdenum_transporter |
cd03297 |
ATP-binding cassette domain of the molybdenum transport system; ModC is an ABC-type ... |
30-227 |
7.36e-26 |
|
ATP-binding cassette domain of the molybdenum transport system; ModC is an ABC-type transporter and the ATPase component of a molybdate transport system that also includes the periplasmic binding protein ModA and the membrane protein ModB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213264 [Multi-domain] Cd Length: 214 Bit Score: 100.83 E-value: 7.36e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 30 SGENWVLMGLNGAGKTTLLSLIYGNHWATTGSIE----VLGETFGKTNVLALKKRIGLIstaVQ--SQFPEHHLAQYIVl 103
Cdd:cd03297 22 NEEVTGIFGASGAGKSTLLRCIAGLEKPDGGTIVlngtVLFDSRKKINLPPQQRKIGLV---FQqyALFPHLNVRENLA- 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 104 sgkFGTIGIHNDFEKNDLNEAIGLLkklGGDELVNKPYRVLSQGQRQLVLIARALLGKPELLILDEPCNGLDLFSRELLL 183
Cdd:cd03297 98 ---FGLKRKRNREDRISVDELLDLL---GLDHLLNRYPAQLSGGEKQRVALARALAAQPELLLLDEPFSALDRALRLQLL 171
|
170 180 190 200
....*....|....*....|....*....|....*....|....
gi 915796356 184 EQINKLAQLPNHPTlLFVSHYTEEILPIFKNIMLLKQGEIFAQG 227
Cdd:cd03297 172 PELKQIKKNLNIPV-IFVTHDLSEAEYLADRIVVMEDGRLQYIG 214
|
|
| ABCC_bacteriocin_exporters |
cd03245 |
ATP-binding cassette domain of bacteriocin exporters, subfamily C; Many non-lantibiotic ... |
10-227 |
1.55e-25 |
|
ATP-binding cassette domain of bacteriocin exporters, subfamily C; Many non-lantibiotic bacteriocins of lactic acid bacteria are produced as precursors which have N-terminal leader peptides that share similarities in amino acid sequence and contain a conserved processing site of two glycine residues in positions -1 and -2. A dedicated ATP-binding cassette (ABC) transporter is responsible for the proteolytic cleavage of the leader peptides and subsequent translocation of the bacteriocins across the cytoplasmic membrane.
Pssm-ID: 213212 [Multi-domain] Cd Length: 220 Bit Score: 99.97 E-value: 1.55e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 10 KNVSF---ERDKIILKNINWSLHSGENWVLMGLNGAGKTTLLSLIYGNHWATTGSIEVLGETFGKTNVLALKKRIGlist 86
Cdd:cd03245 6 RNVSFsypNQEIPALDNVSLTIRAGEKVAIIGRVGSGKSTLLKLLAGLYKPTSGSVLLDGTDIRQLDPADLRRNIG---- 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 87 avqsqfpehHLAQYIVLSgkFGTI--------GIHNDFEKNDLNEAIGLLK-----KLGGDELVNKPYRVLSQGQRQLVL 153
Cdd:cd03245 82 ---------YVPQDVTLF--YGTLrdnitlgaPLADDERILRAAELAGVTDfvnkhPNGLDLQIGERGRGLSGGQRQAVA 150
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 915796356 154 IARALLGKPELLILDEPCNGLDLFSRELLLEQinkLAQLPNHPTLLFVSHYTeEILPIFKNIMLLKQGEIFAQG 227
Cdd:cd03245 151 LARALLNDPPILLLDEPTSAMDMNSEERLKER---LRQLLGDKTLIIITHRP-SLLDLVDRIIVMDSGRIVADG 220
|
|
| ABC_Org_Solvent_Resistant |
cd03261 |
ATP-binding cassette transport system involved in resistance to organic solvents; ABC ... |
7-234 |
2.53e-25 |
|
ATP-binding cassette transport system involved in resistance to organic solvents; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213228 [Multi-domain] Cd Length: 235 Bit Score: 99.88 E-value: 2.53e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 7 LSMKNVSFER-DKIILKNINWSLHSGENWVLMGLNGAGKTTLLSLIYGNHWATTGSIEVLGE---TFGKTNVLALKKRIG 82
Cdd:cd03261 1 IELRGLTKSFgGRTVLKGVDLDVRRGEILAIIGPSGSGKSTLLRLIVGLLRPDSGEVLIDGEdisGLSEAELYRLRRRMG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 83 LIstaVQS-------------QFP--EH-----HLAQYIVLSgKFGTIGIHNDFEKndlneaigllkklggdelvnKPYR 142
Cdd:cd03261 81 ML---FQSgalfdsltvfenvAFPlrEHtrlseEEIREIVLE-KLEAVGLRGAEDL--------------------YPAE 136
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 143 vLSQGQRQLVLIARALLGKPELLILDEPCNGLDLFSRELLLEQINKLAQLPNHpTLLFVSHYTEEILPIFKNIMLLKQGE 222
Cdd:cd03261 137 -LSGGMKKRVALARALALDPELLLYDEPTAGLDPIASGVIDDLIRSLKKELGL-TSIMVTHDLDTAFAIADRIAVLYDGK 214
|
250
....*....|..
gi 915796356 223 IFAQGTRDKILT 234
Cdd:cd03261 215 IVAEGTPEELRA 226
|
|
| ABC_subfamily_A |
cd03263 |
ATP-binding cassette domain of the lipid transporters, subfamily A; The ABCA subfamily ... |
7-228 |
5.91e-25 |
|
ATP-binding cassette domain of the lipid transporters, subfamily A; The ABCA subfamily mediates the transport of a variety of lipid compounds. Mutations of members of ABCA subfamily are associated with human genetic diseases, such as, familial high-density lipoprotein (HDL) deficiency, neonatal surfactant deficiency, degenerative retinopathies, and congenital keratinization disorders. The ABCA1 protein is involved in disorders of cholesterol transport and high-density lipoprotein (HDL) biosynthesis. The ABCA4 (ABCR) protein transports vitamin A derivatives in the outer segments of photoreceptor cells, and therefore, performs a crucial step in the visual cycle. The ABCA genes are not present in yeast. However, evolutionary studies of ABCA genes indicate that they arose as transporters that subsequently duplicated and that certain sets of ABCA genes were lost in different eukaryotic lineages.
Pssm-ID: 213230 [Multi-domain] Cd Length: 220 Bit Score: 98.73 E-value: 5.91e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 7 LSMKNVS--FE-RDKIILKNINWSLHSGENWVLMGLNGAGKTTLLSLIYGNHWATTGSIEVLGeTFGKTNVLALKKRIGL 83
Cdd:cd03263 1 LQIRNLTktYKkGTKPAVDDLSLNVYKGEIFGLLGHNGAGKTTTLKMLTGELRPTSGTAYING-YSIRTDRKAARQSLGY 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 84 IstavqSQF--------PEHHLAQYIVLSGKFGTIGIHndfekndlnEAIGLLKKLGGDELVNKPYRVLSQGQRQLVLIA 155
Cdd:cd03263 80 C-----PQFdalfdeltVREHLRFYARLKGLPKSEIKE---------EVELLLRVLGLTDKANKRARTLSGGMKRKLSLA 145
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 915796356 156 RALLGKPELLILDEPCNGLDLFSRELLLEQINKLAQlpnHPTLLFVSHYTEEILPIFKNIMLLKQGEIFAQGT 228
Cdd:cd03263 146 IALIGGPSVLLLDEPTSGLDPASRRAIWDLILEVRK---GRSIILTTHSMDEAEALCDRIAIMSDGKLRCIGS 215
|
|
| cbiO |
PRK13637 |
energy-coupling factor transporter ATPase; |
9-235 |
7.04e-25 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 237455 [Multi-domain] Cd Length: 287 Bit Score: 100.12 E-value: 7.04e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 9 MKNVSFErdKIILKNINWSLHSGENWVLMGLNGAGKTTLLSLIYGNHWATTGSIEVLGE--TFGKTNVLALKKRIGLISt 86
Cdd:PRK13637 13 MEGTPFE--KKALDNVNIEIEDGEFVGLIGHTGSGKSTLIQHLNGLLKPTSGKIIIDGVdiTDKKVKLSDIRKKVGLVF- 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 87 avqsQFPEHHL-AQYIVLSGKFG--TIGIHNDFEKNDLNEAIGLLKkLGGDELVNKPYRVLSQGQRQLVLIARALLGKPE 163
Cdd:PRK13637 90 ----QYPEYQLfEETIEKDIAFGpiNLGLSEEEIENRVKRAMNIVG-LDYEDYKDKSPFELSGGQKRRVAIAGVVAMEPK 164
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 915796356 164 LLILDEPCNGLDLFSRELLLEQINKLAQLPNHpTLLFVSHYTEEILPIFKNIMLLKQGEIFAQGTRDKILTE 235
Cdd:PRK13637 165 ILILDEPTAGLDPKGRDEILNKIKELHKEYNM-TIILVSHSMEDVAKLADRIIVMNKGKCELQGTPREVFKE 235
|
|
| ABC_putative_ATPase |
cd03269 |
ATP-binding cassette domain of an uncharacterized transporter; This subgroup is related to the ... |
16-227 |
1.01e-24 |
|
ATP-binding cassette domain of an uncharacterized transporter; This subgroup is related to the subfamily A transporters involved in drug resistance, nodulation, lipid transport, and bacteriocin and lantibiotic immunity. In eubacteria and archaea, the typical organization consists of one ABC and one or two integral membranes. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region in addition to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213236 [Multi-domain] Cd Length: 210 Bit Score: 97.74 E-value: 1.01e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 16 RDKIILKNINWSLHSGENWVLMGLNGAGKTTLLSLIYGNHWATTGSIEVLGETFGktnvLALKKRIGLI--------STA 87
Cdd:cd03269 11 GRVTALDDISFSVEKGEIFGLLGPNGAGKTTTIRMILGIILPDSGEVLFDGKPLD----IAARNRIGYLpeerglypKMK 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 88 VQSQFpeHHLAQyivlsgkfgtigIHNDFEKNDLNEAIGLLKKLGGDELVNKPYRVLSQGQRQLVLIARALLGKPELLIL 167
Cdd:cd03269 87 VIDQL--VYLAQ------------LKGLKKEEARRRIDEWLERLELSEYANKRVEELSKGNQQKVQFIAAVIHDPELLIL 152
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 168 DEPCNGLDLFSRELLLEQINKLAQlpNHPTLLFVSHYTEEILPIFKNIMLLKQGEIFAQG 227
Cdd:cd03269 153 DEPFSGLDPVNVELLKDVIRELAR--AGKTVILSTHQMELVEELCDRVLLLNKGRAVLYG 210
|
|
| MglA |
COG1129 |
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; |
3-209 |
2.13e-24 |
|
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];
Pssm-ID: 440745 [Multi-domain] Cd Length: 497 Bit Score: 101.25 E-value: 2.13e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 3 NNAVLSMKNVSferdK-----IILKNINWSLHSGENWVLMGLNGAGKTTLLSLIYGNHWATTGSIEVLGETFGKTNVL-A 76
Cdd:COG1129 1 AEPLLEMRGIS----KsfggvKALDGVSLELRPGEVHALLGENGAGKSTLMKILSGVYQPDSGEILLDGEPVRFRSPRdA 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 77 LKKRIGLIStavQ--SQFPehHL--AQYIVL---SGKFGTIgihnDFEKndLN-EAIGLLKKLGGDELVNKPYRVLSQGQ 148
Cdd:COG1129 77 QAAGIAIIH---QelNLVP--NLsvAENIFLgrePRRGGLI----DWRA--MRrRARELLARLGLDIDPDTPVGDLSVAQ 145
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 915796356 149 RQLVLIARALLGKPELLILDEPCNGLDLFSRELLLEQINKLAQlpNHPTLLFVSHYTEEIL 209
Cdd:COG1129 146 QQLVEIARALSRDARVLILDEPTASLTEREVERLFRIIRRLKA--QGVAIIYISHRLDEVF 204
|
|
| Uup |
COG0488 |
ATPase components of ABC transporters with duplicated ATPase domains [General function ... |
6-203 |
2.30e-24 |
|
ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only];
Pssm-ID: 440254 [Multi-domain] Cd Length: 520 Bit Score: 101.29 E-value: 2.30e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 6 VLSMKNVSFER-DKIILKNINWSLHSGENWVLMGLNGAGKTTLLSLIYGNHWATTGSIEvLGETFgktnvlalkkRIGLi 84
Cdd:COG0488 315 VLELEGLSKSYgDKTLLDDLSLRIDRGDRIGLIGPNGAGKSTLLKLLAGELEPDSGTVK-LGETV----------KIGY- 382
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 85 stavqsqFPEHH--------LAQYIvlsgkfgtigiHNDFEKNDLNEAIGLLKKLG--GDElVNKPYRVLSQGQRQLVLI 154
Cdd:COG0488 383 -------FDQHQeeldpdktVLDEL-----------RDGAPGGTEQEVRGYLGRFLfsGDD-AFKPVGVLSGGEKARLAL 443
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 915796356 155 ARALLGKPELLILDEPCNGLDLFSRELLLEQINklaqlpNHP-TLLFVSH 203
Cdd:COG0488 444 AKLLLSPPNVLLLDEPTNHLDIETLEALEEALD------DFPgTVLLVSH 487
|
|
| type_I_sec_LssB |
TIGR03375 |
type I secretion system ATPase, LssB family; Type I protein secretion is a system in some ... |
10-236 |
5.72e-24 |
|
type I secretion system ATPase, LssB family; Type I protein secretion is a system in some Gram-negative bacteria to export proteins (often proteases) across both inner and outer membranes to the extracellular medium. This is one of three proteins of the type I secretion apparatus. Targeted proteins are not cleaved at the N-terminus, but rather carry signals located toward the extreme C-terminus to direct type I secretion. This model is related to models TIGR01842 and TIGR01846, and to bacteriocin ABC transporters that cleave their substrates during export. [Protein fate, Protein and peptide secretion and trafficking, Cellular processes, Pathogenesis]
Pssm-ID: 274550 [Multi-domain] Cd Length: 694 Bit Score: 100.71 E-value: 5.72e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 10 KNVSF---ERDKIILKNINWSLHSGENWVLMGLNGAGKTTLLSLIYGNHWATTGSIEVLGETFGKTNVLALKKRIGlist 86
Cdd:TIGR03375 467 RNVSFaypGQETPALDNVSLTIRPGEKVAIIGRIGSGKSTLLKLLLGLYQPTEGSVLLDGVDIRQIDPADLRRNIG---- 542
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 87 avqsqfpehHLAQYIVLSgkFGTIGiHN------DFEKNDLNEAIGL--------LKKLGGDELVNKPYRVLSQGQRQLV 152
Cdd:TIGR03375 543 ---------YVPQDPRLF--YGTLR-DNialgapYADDEEILRAAELagvtefvrRHPDGLDMQIGERGRSLSGGQRQAV 610
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 153 LIARALLGKPELLILDEPCNGLDLFSRELLLEqinKLAQLPNHPTLLFVSHYTeEILPIFKNIMLLKQGEIFAQGTRDKI 232
Cdd:TIGR03375 611 ALARALLRDPPILLLDEPTSAMDNRSEERFKD---RLKRWLAGKTLVLVTHRT-SLLDLVDRIIVMDNGRIVADGPKDQV 686
|
....
gi 915796356 233 LTEN 236
Cdd:TIGR03375 687 LEAL 690
|
|
| ThiQ |
COG3840 |
ABC-type thiamine transport system, ATPase component ThiQ [Coenzyme transport and metabolism]; |
7-236 |
7.32e-24 |
|
ABC-type thiamine transport system, ATPase component ThiQ [Coenzyme transport and metabolism];
Pssm-ID: 443051 [Multi-domain] Cd Length: 232 Bit Score: 95.98 E-value: 7.32e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 7 LSMKNVSFERDKIILkNINWSLHSGENWVLMGLNGAGKTTLLSLIYGNHWATTGSIEVLGETFGKTNVlalKKRigLIST 86
Cdd:COG3840 2 LRLDDLTYRYGDFPL-RFDLTIAAGERVAILGPSGAGKSTLLNLIAGFLPPDSGRILWNGQDLTALPP---AER--PVSM 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 87 AVQSQ--FPehHL--AQYIVLsgkfgtiGIH-----NDFEKNDLNEAiglLKKLGGDELVN-KPYRvLSQGQRQLVLIAR 156
Cdd:COG3840 76 LFQENnlFP--HLtvAQNIGL-------GLRpglklTAEQRAQVEQA---LERVGLAGLLDrLPGQ-LSGGQRQRVALAR 142
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 157 ALLGKPELLILDEPCNGLDLFSRE---LLLEQINKLAQLpnhpTLLFVSHYTEEILPIFKNIMLLKQGEIFAQGTRDKIL 233
Cdd:COG3840 143 CLVRKRPILLLDEPFSALDPALRQemlDLVDELCRERGL----TVLMVTHDPEDAARIADRVLLVADGRIAADGPTAALL 218
|
...
gi 915796356 234 TEN 236
Cdd:COG3840 219 DGE 221
|
|
| DppF |
COG1124 |
ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid ... |
7-233 |
7.90e-24 |
|
ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];
Pssm-ID: 440741 [Multi-domain] Cd Length: 248 Bit Score: 96.41 E-value: 7.90e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 7 LSMKNVS-----FERDKIILKNINWSLHSGENWVLMGLNGAGKTTLLSLIYGNHWATTGSIEVLGETFGKTNVLALKKRI 81
Cdd:COG1124 2 LEVRNLSvsygqGGRRVPVLKDVSLEVAPGESFGLVGESGSGKSTLLRALAGLERPWSGEVTFDGRPVTRRRRKAFRRRV 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 82 GLIStavqsQFPehhlaqYIVLSGKFgTIG--------IHNdfeKNDLNEAIG-LLKKLG-GDELVNK-PYRvLSQGQRQ 150
Cdd:COG1124 82 QMVF-----QDP------YASLHPRH-TVDrilaeplrIHG---LPDREERIAeLLEQVGlPPSFLDRyPHQ-LSGGQRQ 145
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 151 LVLIARALLGKPELLILDEPCNGLDLFSR-EL--LLEQINKLAQLpnhpTLLFVSHYTEEILPIFKNIMLLKQGEIFAQG 227
Cdd:COG1124 146 RVAIARALILEPELLLLDEPTSALDVSVQaEIlnLLKDLREERGL----TYLFVSHDLAVVAHLCDRVAVMQNGRIVEEL 221
|
....*.
gi 915796356 228 TRDKIL 233
Cdd:COG1124 222 TVADLL 227
|
|
| ABC_NatA_like |
cd03267 |
ATP-binding cassette domain of an uncharacterized transporter similar in sequence to NatA; ... |
16-227 |
1.31e-23 |
|
ATP-binding cassette domain of an uncharacterized transporter similar in sequence to NatA; NatA is the ATPase component of a bacterial ABC-type Na+ transport system called NatAB, which catalyzes ATP-dependent electrogenic Na+ extrusion without mechanically coupled to proton or K+ uptake. NatB possess six putative membrane spanning regions at its C-terminus. In B. subtilis, NatAB is inducible by agents such as ethanol and protonophores, which lower the proton-motive force across the membrane. The closest sequence similarity to NatA is exhibited by DrrA of the two-component daunorubicin- and doxorubicin-efflux system. Hence, the functional NatAB is presumably assembled with two copies of the single ATP-binding protein and the single integral membrane protein.
Pssm-ID: 213234 [Multi-domain] Cd Length: 236 Bit Score: 95.48 E-value: 1.31e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 16 RDKIILKNINWSLHSGENWVLMGLNGAGKTTLLSLIYGNHWATTGSIEVLGETFGKtNVLALKKRIGLI---STAVQSQF 92
Cdd:cd03267 32 REVEALKGISFTIEKGEIVGFIGPNGAGKTTTLKILSGLLQPTSGEVRVAGLVPWK-RRKKFLRRIGVVfgqKTQLWWDL 110
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 93 P-----EHHLAQYIVLSGKFgtigihndfeKNDLNEAIGLLKkLGgdELVNKPYRVLSQGQRQLVLIARALLGKPELLIL 167
Cdd:cd03267 111 PvidsfYLLAAIYDLPPARF----------KKRLDELSELLD-LE--ELLDTPVRQLSLGQRMRAEIAAALLHEPEILFL 177
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 915796356 168 DEPCNGLDLFSRELL---LEQINKLAQlpnhPTLLFVSHYTEEILPIFKNIMLLKQGEIFAQG 227
Cdd:cd03267 178 DEPTIGLDVVAQENIrnfLKEYNRERG----TTVLLTSHYMKDIEALARRVLVIDKGRLLYDG 236
|
|
| MlaF |
COG1127 |
ATPase subunit MlaF of the ABC-type intermembrane phospholipid transporter Mla [Cell wall ... |
2-234 |
4.18e-23 |
|
ATPase subunit MlaF of the ABC-type intermembrane phospholipid transporter Mla [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440744 [Multi-domain] Cd Length: 241 Bit Score: 94.28 E-value: 4.18e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 2 TNNAVLSMKNVSFER-DKIILKNINWSLHSGENWVLMGLNGAGKTTLLSLIYGNHWATTGSIEVLGETFGKTNV---LAL 77
Cdd:COG1127 1 MSEPMIEVRNLTKSFgDRVVLDGVSLDVPRGEILAIIGGSGSGKSVLLKLIIGLLRPDSGEILVDGQDITGLSEkelYEL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 78 KKRIG-------LIStavqS-------QFPehhLAQYIVLSGKfgtigihndfEKNDLneAIGLLKKLGGDELVNKPYRV 143
Cdd:COG1127 81 RRRIGmlfqggaLFD----SltvfenvAFP---LREHTDLSEA----------EIREL--VLEKLELVGLPGAADKMPSE 141
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 144 LSQGQRQLVLIARALLGKPELLILDEPCNGLDLFSRELLLEQINKLAQLpNHPTLLFVSHYTEEILPIFKNIMLLKQGEI 223
Cdd:COG1127 142 LSGGMRKRVALARALALDPEILLYDEPTAGLDPITSAVIDELIRELRDE-LGLTSVVVTHDLDSAFAIADRVAVLADGKI 220
|
250
....*....|.
gi 915796356 224 FAQGTRDKILT 234
Cdd:COG1127 221 IAEGTPEELLA 231
|
|
| ModC |
COG4148 |
ABC-type molybdate transport system, ATPase component ModC [Inorganic ion transport and ... |
35-234 |
9.93e-23 |
|
ABC-type molybdate transport system, ATPase component ModC [Inorganic ion transport and metabolism]; ABC-type molybdate transport system, ATPase component ModC is part of the Pathway/BioSystem: Molybdopterin biosynthesis
Pssm-ID: 443319 [Multi-domain] Cd Length: 358 Bit Score: 95.17 E-value: 9.93e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 35 VLMGLNGAGKTTLLSLIYGNHWATTGSIEVLGETF----GKTNVLALKKRIGLIstavqsqFPEHHL-AQYIVLSG-KFG 108
Cdd:COG4148 29 ALFGPSGSGKTTLLRAIAGLERPDSGRIRLGGEVLqdsaRGIFLPPHRRRIGYV-------FQEARLfPHLSVRGNlLYG 101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 109 TIGIHNDFEKNDLNEAIGLLkklGGDELVNKPYRVLSQGQRQLVLIARALLGKPELLILDEPCNGLDLFSR-ELL--LEQ 185
Cdd:COG4148 102 RKRAPRAERRISFDEVVELL---GIGHLLDRRPATLSGGERQRVAIGRALLSSPRLLLMDEPLAALDLARKaEILpyLER 178
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 915796356 186 INKLAQLPnhptLLFVSHYTEEILPIFKNIMLLKQGEIFAQGTRDKILT 234
Cdd:COG4148 179 LRDELDIP----ILYVSHSLDEVARLADHVVLLEQGRVVASGPLAEVLS 223
|
|
| CydC |
COG4987 |
ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease ... |
5-236 |
1.46e-22 |
|
ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease components [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 444011 [Multi-domain] Cd Length: 569 Bit Score: 96.37 E-value: 1.46e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 5 AVLSMKNVSF---ERDKIILKNINWSLHSGENWVLMGLNGAGKTTLLSLIYGNHWATTGSIEVLGETFGKTNVLALKKRI 81
Cdd:COG4987 332 PSLELEDVSFrypGAGRPVLDGLSLTLPPGERVAIVGPSGSGKSTLLALLLRFLDPQSGSITLGGVDLRDLDEDDLRRRI 411
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 82 GLIStavqsQfpEHHLaqyivlsgkF-GTIGihndfekNDL---------NEAIGLLKKLGGDELVNKP-----YRV--- 143
Cdd:COG4987 412 AVVP-----Q--RPHL---------FdTTLR-------ENLrlarpdatdEELWAALERVGLGDWLAALpdgldTWLgeg 468
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 144 ---LSQGQRQLVLIARALLGKPELLILDEPCNGLDLFSRELLLEQInkLAQLPNHpTLLFVSHYTEEiLPIFKNIMLLKQ 220
Cdd:COG4987 469 grrLSGGERRRLALARALLRDAPILLLDEPTEGLDAATEQALLADL--LEALAGR-TVLLITHRLAG-LERMDRILVLED 544
|
250
....*....|....*.
gi 915796356 221 GEIFAQGTRDKILTEN 236
Cdd:COG4987 545 GRIVEQGTHEELLAQN 560
|
|
| cbiO |
TIGR01166 |
cobalt transport protein ATP-binding subunit; This model describes the ATP binding subunit of ... |
14-203 |
2.36e-22 |
|
cobalt transport protein ATP-binding subunit; This model describes the ATP binding subunit of the multisubunit cobalt transporter in bacteria and its equivalents in archaea. The model is restricted to ATP subunit that is a part of the cobalt transporter, which belongs to the ABC transporter superfamily (ATP Binding Cassette). The model excludes ATP binding subunit that are associated with other transporters belonging to ABC transporter superfamily. This superfamily includes two groups, one which catalyze the uptake of small molecules, including ions from the external milieu and the other group which is engaged in the efflux of small molecular weight compounds and ions from within the cell. Energy derived from the hydrolysis of ATP drive the both the process of uptake and efflux. [Transport and binding proteins, Cations and iron carrying compounds]
Pssm-ID: 130234 [Multi-domain] Cd Length: 190 Bit Score: 90.95 E-value: 2.36e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 14 FERDKIILKNINWSLHSGENWVLMGLNGAGKTTLLSLIYGNHWATTGSIEVLGET--FGKTNVLALKKRIGLIStavqsQ 91
Cdd:TIGR01166 1 YPGGPEVLKGLNFAAERGEVLALLGANGAGKSTLLLHLNGLLRPQSGAVLIDGEPldYSRKGLLERRQRVGLVF-----Q 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 92 FPEHHLAQYIVLSG-KFG--TIGIHNDFEKNDLNEAiglLKKLGGDELVNKPYRVLSQGQRQLVLIARALLGKPELLILD 168
Cdd:TIGR01166 76 DPDDQLFAADVDQDvAFGplNLGLSEAEVERRVREA---LTAVGASGLRERPTHCLSGGEKKRVAIAGAVAMRPDVLLLD 152
|
170 180 190
....*....|....*....|....*....|....*
gi 915796356 169 EPCNGLDLFSRELLLEQINKLAQLPNhpTLLFVSH 203
Cdd:TIGR01166 153 EPTAGLDPAGREQMLAILRRLRAEGM--TVVISTH 185
|
|
| ABC_Carb_Solutes_like |
cd03259 |
ATP-binding cassette domain of the carbohydrate and solute transporters-like; This family is ... |
7-227 |
2.67e-22 |
|
ATP-binding cassette domain of the carbohydrate and solute transporters-like; This family is comprised of proteins involved in the transport of apparently unrelated solutes and proteins specific for di- and oligosaccharides and polyols. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213226 [Multi-domain] Cd Length: 213 Bit Score: 91.43 E-value: 2.67e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 7 LSMKNVS-FERDKIILKNINWSLHSGENWVLMGLNGAGKTTLLSLIYGNHWATTGSIEVLGETFgkTNVLALKKRIGLI- 84
Cdd:cd03259 1 LELKGLSkTYGSVRALDDLSLTVEPGEFLALLGPSGCGKTTLLRLIAGLERPDSGEILIDGRDV--TGVPPERRNIGMVf 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 85 -STAVqsqFPehHL--AQYIVLSGKFGTIGihndfEKNDLNEAIGLLKKLGGDELVNKPYRVLSQGQRQLVLIARALLGK 161
Cdd:cd03259 79 qDYAL---FP--HLtvAENIAFGLKLRGVP-----KAEIRARVRELLELVGLEGLLNRYPHELSGGQQQRVALARALARE 148
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 915796356 162 PELLILDEPCNGLDLFSRELLLEQINKLaQLPNHPTLLFVSHYTEEILPIFKNIMLLKQGEIFAQG 227
Cdd:cd03259 149 PSLLLLDEPLSALDAKLREELREELKEL-QRELGITTIYVTHDQEEALALADRIAVMNEGRIVQVG 213
|
|
| ABC_PotA_N |
cd03300 |
ATP-binding cassette domain of the polyamine transporter; PotA is an ABC-type transporter and ... |
7-249 |
6.66e-22 |
|
ATP-binding cassette domain of the polyamine transporter; PotA is an ABC-type transporter and the ATPase component of the spermidine/putrescine-preferential uptake system consisting of PotA, -B, -C, and -D. PotA has two domains with the N-terminal domain containing the ATPase activity and the residues required for homodimerization with PotA and heterdimerization with PotB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213267 [Multi-domain] Cd Length: 232 Bit Score: 90.76 E-value: 6.66e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 7 LSMKNVS-FERDKIILKNINWSLHSGENWVLMGLNGAGKTTLLSLIYGNHWATTGSIEVLGETFgkTNVLALKKRIGlis 85
Cdd:cd03300 1 IELENVSkFYGGFVALDGVSLDIKEGEFFTLLGPSGCGKTTLLRLIAGFETPTSGEILLDGKDI--TNLPPHKRPVN--- 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 86 TAVQSQ--FPEHHLAQYIVlsgkFG--TIGIHNDFEKNDLNEAIGLLKKlggDELVNKPYRVLSQGQRQLVLIARALLGK 161
Cdd:cd03300 76 TVFQNYalFPHLTVFENIA----FGlrLKKLPKAEIKERVAEALDLVQL---EGYANRKPSQLSGGQQQRVAIARALVNE 148
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 162 PELLILDEPCNGLDLFSRELLLEQINKLaQLPNHPTLLFVSHYTEEILPIFKNIMLLKQGEIFAQGTRDKIltenvlskf 241
Cdd:cd03300 149 PKVLLLDEPLGALDLKLRKDMQLELKRL-QKELGITFVFVTHDQEEALTMSDRIAVMNKGKIQQIGTPEEI--------- 218
|
....*...
gi 915796356 242 YPKPIKIF 249
Cdd:cd03300 219 YEEPANRF 226
|
|
| ABC_ModC_like |
cd03299 |
ATP-binding cassette domain similar to the molybdate transporter; Archaeal protein closely ... |
21-254 |
7.10e-22 |
|
ATP-binding cassette domain similar to the molybdate transporter; Archaeal protein closely related to ModC. ModC is an ABC-type transporter and the ATPase component of a molybdate transport system that also includes the periplasmic binding protein ModA and the membrane protein ModB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213266 [Multi-domain] Cd Length: 235 Bit Score: 90.86 E-value: 7.10e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 21 LKNINWSLHSGENWVLMGLNGAGKTTLLSLIYGNHWATTGSIEVLGETFgkTNVLALKKRIGLISTAvQSQFPehHLAQY 100
Cdd:cd03299 15 LKNVSLEVERGDYFVILGPTGSGKSVLLETIAGFIKPDSGKILLNGKDI--TNLPPEKRDISYVPQN-YALFP--HMTVY 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 101 IVLSgkFGTIGIHNDfEKNDLNEAIGLLKKLGGDELVNKPYRVLSQGQRQLVLIARALLGKPELLILDEPCNGLDLFSRE 180
Cdd:cd03299 90 KNIA--YGLKKRKVD-KKEIERKVLEIAEMLGIDHLLNRKPETLSGGEQQRVAIARALVVNPKILLLDEPFSALDVRTKE 166
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 915796356 181 LLLEQInKLAQLPNHPTLLFVSHYTEEILPIFKNIMLLKQGEIFAQGTRdkiltENVLSKfyPKPIKI--FPVTNN 254
Cdd:cd03299 167 KLREEL-KKIRKEFGVTVLHVTHDFEEAWALADKVAIMLNGKLIQVGKP-----EEVFKK--PKNEFVaeFLGFNN 234
|
|
| ABCF_EF-3 |
cd03221 |
ATP-binding cassette domain of elongation factor 3, subfamily F; Elongation factor 3 (EF-3) is ... |
7-203 |
7.95e-22 |
|
ATP-binding cassette domain of elongation factor 3, subfamily F; Elongation factor 3 (EF-3) is a cytosolic protein required by fungal ribosomes for in vitro protein synthesis and for in vivo growth. EF-3 stimulates the binding of the EF-1: GTP: aa-tRNA ternary complex to the ribosomal A site by facilitated release of the deacylated tRNA from the E site. The reaction requires ATP hydrolysis. EF-3 contains two ATP nucleotide binding sequence (NBS) motifs. NBSI is sufficient for the intrinsic ATPase activity. NBSII is essential for the ribosome-stimulated functions.
Pssm-ID: 213188 [Multi-domain] Cd Length: 144 Bit Score: 88.27 E-value: 7.95e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 7 LSMKNVSFER-DKIILKNINWSLHSGENWVLMGLNGAGKTTLLSLIYGNHWATTGSIEVlgetfGKTNVLAlkkriglis 85
Cdd:cd03221 1 IELENLSKTYgGKLLLKDISLTINPGDRIGLVGRNGAGKSTLLKLIAGELEPDEGIVTW-----GSTVKIG--------- 66
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 86 tavqsqfpehHLAQyivlsgkfgtigihndfekndlneaigllkklggdelvnkpyrvLSQGQRQLVLIARALLGKPELL 165
Cdd:cd03221 67 ----------YFEQ--------------------------------------------LSGGEKMRLALAKLLLENPNLL 92
|
170 180 190
....*....|....*....|....*....|....*...
gi 915796356 166 ILDEPCNGLDLFSRELLLEQINKLaqlpnHPTLLFVSH 203
Cdd:cd03221 93 LLDEPTNHLDLESIEALEEALKEY-----PGTVILVSH 125
|
|
| hmuV |
PRK13548 |
hemin importer ATP-binding subunit; Provisional |
5-242 |
1.24e-21 |
|
hemin importer ATP-binding subunit; Provisional
Pssm-ID: 237422 [Multi-domain] Cd Length: 258 Bit Score: 90.60 E-value: 1.24e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 5 AVLSMKNVSFER-DKIILKNINWSLHSGENWVLMGLNGAGKTTLLSLIYGNHWATTGSIEVLGETFGKTNVLALKKRIGL 83
Cdd:PRK13548 1 AMLEARNLSVRLgGRTLLDDVSLTLRPGEVVAILGPNGAGKSTLLRALSGELSPDSGEVRLNGRPLADWSPAELARRRAV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 84 ISTAVQSQFPehHLAQYIVLSGkfgtIGIHNDFEKNDLNEAIGLLKKLGGDELVNKPYRVLSQGQRQLVLIARALL---- 159
Cdd:PRK13548 81 LPQHSSLSFP--FTVEEVVAMG----RAPHGLSRAEDDALVAAALAQVDLAHLAGRDYPQLSGGEQQRVQLARVLAqlwe 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 160 --GKPELLILDEPCNGLDLFSRELLLEQINKLAQlPNHPTLLFVSH-------YTEeilpifkNIMLLKQGEIFAQGTRD 230
Cdd:PRK13548 155 pdGPPRWLLLDEPTSALDLAHQHHVLRLARQLAH-ERGLAVIVVLHdlnlaarYAD-------RIVLLHQGRLVADGTPA 226
|
250
....*....|..
gi 915796356 231 KILTENVLSKFY 242
Cdd:PRK13548 227 EVLTPETLRRVY 238
|
|
| PRK13536 |
PRK13536 |
nodulation factor ABC transporter ATP-binding protein NodI; |
3-237 |
1.49e-21 |
|
nodulation factor ABC transporter ATP-binding protein NodI;
Pssm-ID: 237419 [Multi-domain] Cd Length: 340 Bit Score: 91.82 E-value: 1.49e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 3 NNAVLSMKNVSFE--------RDKIILKNINWSLHSGENWVLMGLNGAGKTTLLSLIYGNHWATTGSIEVLGETFGKTNV 74
Cdd:PRK13536 31 ASIPGSMSTVAIDlagvsksyGDKAVVNGLSFTVASGECFGLLGPNGAGKSTIARMILGMTSPDAGKITVLGVPVPARAR 110
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 75 LAlKKRIGLIStavqsQF----PEHHLAQYIVLSGKFgtIGIHNdfekNDLNEAI-GLLKKLGGDELVNKPYRVLSQGQR 149
Cdd:PRK13536 111 LA-RARIGVVP-----QFdnldLEFTVRENLLVFGRY--FGMST----REIEAVIpSLLEFARLESKADARVSDLSGGMK 178
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 150 QLVLIARALLGKPELLILDEPCNGLDLFSRELLLEQINKLaqLPNHPTLLFVSHYTEEILPIFKNIMLLKQGEIFAQGTR 229
Cdd:PRK13536 179 RRLTLARALINDPQLLILDEPTTGLDPHARHLIWERLRSL--LARGKTILLTTHFMEEAERLCDRLCVLEAGRKIAEGRP 256
|
....*...
gi 915796356 230 DKILTENV 237
Cdd:PRK13536 257 HALIDEHI 264
|
|
| ABC_Pro_Gly_Betaine |
cd03294 |
ATP-binding cassette domain of the osmoprotectant proline/glycine betaine uptake system; This ... |
21-235 |
1.58e-21 |
|
ATP-binding cassette domain of the osmoprotectant proline/glycine betaine uptake system; This family comprises the glycine betaine/L-proline ATP binding subunit in bacteria and its equivalents in archaea. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporters is the obligatory coupling of ATP hydrolysis to substrate translocation. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213261 [Multi-domain] Cd Length: 269 Bit Score: 90.78 E-value: 1.58e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 21 LKNINWSLHSGENWVLMGLNGAGKTTLLSLIYGNHWATTGSIEVLGETFGKTNVLAL----KKRIGLIstaVQS--QFPe 94
Cdd:cd03294 40 VNDVSLDVREGEIFVIMGLSGSGKSTLLRCINRLIEPTSGKVLIDGQDIAAMSRKELrelrRKKISMV---FQSfaLLP- 115
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 95 hHLAqyiVLSG-KFGtIGIHNDFEKNDLNEAIGLLKK--LGGDElvNKPYRVLSQGQRQLVLIARALLGKPELLILDEPC 171
Cdd:cd03294 116 -HRT---VLENvAFG-LEVQGVPRAEREERAAEALELvgLEGWE--HKYPDELSGGMQQRVGLARALAVDPDILLMDEAF 188
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 915796356 172 NGLD-LFSREL---LLEQINKLaqlpnHPTLLFVSHYTEEILPIFKNIMLLKQGEIFAQGTRDKILTE 235
Cdd:cd03294 189 SALDpLIRREMqdeLLRLQAEL-----QKTIVFITHDLDEALRLGDRIAIMKDGRLVQVGTPEEILTN 251
|
|
| LivG |
COG0411 |
ABC-type branched-chain amino acid transport system, ATPase component LivG [Amino acid ... |
21-233 |
1.88e-21 |
|
ABC-type branched-chain amino acid transport system, ATPase component LivG [Amino acid transport and metabolism];
Pssm-ID: 440180 [Multi-domain] Cd Length: 257 Bit Score: 90.10 E-value: 1.88e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 21 LKNINWSLHSGEnwvLMGL---NGAGKTTLLSLIYGNHWATTGSIEVLGEtfgktNVLALK--KRIGL-IS-----TAVq 89
Cdd:COG0411 20 VDDVSLEVERGE---IVGLigpNGAGKTTLFNLITGFYRPTSGRILFDGR-----DITGLPphRIARLgIArtfqnPRL- 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 90 sqFPE-----------HHLAQYIVLSGKFGTIGIHNDfEKNDLNEAIGLLKKLGGDELVNKPYRVLSQGQRQLVLIARAL 158
Cdd:COG0411 91 --FPEltvlenvlvaaHARLGRGLLAALLRLPRARRE-EREARERAEELLERVGLADRADEPAGNLSYGQQRRLEIARAL 167
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 915796356 159 LGKPELLILDEPCNGLDLFSRELLLEQINKLAQLPNHpTLLFVSHYTEEILPIFKNIMLLKQGEIFAQGTRDKIL 233
Cdd:COG0411 168 ATEPKLLLLDEPAAGLNPEETEELAELIRRLRDERGI-TILLIEHDMDLVMGLADRIVVLDFGRVIAEGTPAEVR 241
|
|
| CysA |
COG1118 |
ABC-type sulfate/molybdate transport systems, ATPase component [Inorganic ion transport and ... |
21-233 |
2.17e-21 |
|
ABC-type sulfate/molybdate transport systems, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 440735 [Multi-domain] Cd Length: 348 Bit Score: 91.36 E-value: 2.17e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 21 LKNINWSLHSGENWVLMGLNGAGKTTLLSLIYGNHWATTGSIEVLGETFgKTNVLALKKRIGLIStavqsQ----FPehH 96
Cdd:COG1118 18 LDDVSLEIASGELVALLGPSGSGKTTLLRIIAGLETPDSGRIVLNGRDL-FTNLPPRERRVGFVF-----QhyalFP--H 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 97 L--AQYIvlsgKFGtigihndFEKNDLNEAI------GLLKKLGGDELVN-KPyRVLSQGQRQLVLIARALLGKPELLIL 167
Cdd:COG1118 90 MtvAENI----AFG-------LRVRPPSKAEirarveELLELVQLEGLADrYP-SQLSGGQRQRVALARALAVEPEVLLL 157
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 915796356 168 DEPCNGLDLFSR-EL------LLEQInklaqlpnHPTLLFVSHYTEEILPIFKNIMLLKQGEIFAQGTRDKIL 233
Cdd:COG1118 158 DEPFGALDAKVRkELrrwlrrLHDEL--------GGTTVFVTHDQEEALELADRVVVMNQGRIEQVGTPDEVY 222
|
|
| ABC_BcrA_bacitracin_resist |
cd03268 |
ATP-binding cassette domain of the bacitracin-resistance transporter; The BcrA subfamily ... |
17-227 |
2.39e-21 |
|
ATP-binding cassette domain of the bacitracin-resistance transporter; The BcrA subfamily represents ABC transporters involved in peptide antibiotic resistance. Bacitracin is a dodecapeptide antibiotic produced by B. licheniformis and B. subtilis. The synthesis of bacitracin is non-ribosomally catalyzed by a multi-enzyme complex BcrABC. Bacitracin has potent antibiotic activity against gram-positive bacteria. The inhibition of peptidoglycan biosynthesis is the best characterized bacterial effect of bacitracin. The bacitracin resistance of B. licheniformis is mediated by the ABC transporter Bcr which is composed of two identical BcrA ATP-binding subunits and one each of the integral membrane proteins, BcrB and BcrC. B. subtilis cells carrying bcr genes on high-copy number plasmids develop collateral detergent sensitivity, a similar phenomenon in human cells with overexpressed multi-drug resistance P-glycoprotein.
Pssm-ID: 213235 [Multi-domain] Cd Length: 208 Bit Score: 88.81 E-value: 2.39e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 17 DKIILKNINWSLHSGENWVLMGLNGAGKTTLLSLIYGNHWATTGSIEVLGETFGKtNVLALKkRIG-LIStaVQSQFPEh 95
Cdd:cd03268 12 KKRVLDDISLHVKKGEIYGFLGPNGAGKTTTMKIILGLIKPDSGEITFDGKSYQK-NIEALR-RIGaLIE--APGFYPN- 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 96 hlaqyivLSGK--FGTIGIHNDFEKNDLNEAIGLLkklGGDELVNKPYRVLSQGQRQLVLIARALLGKPELLILDEPCNG 173
Cdd:cd03268 87 -------LTARenLRLLARLLGIRKKRIDEVLDVV---GLKDSAKKKVKGFSLGMKQRLGIALALLGNPDLLILDEPTNG 156
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 915796356 174 LDLFSRELLLEQINKLAQlpNHPTLLFVSHYTEEILPIFKNIMLLKQGEIFAQG 227
Cdd:cd03268 157 LDPDGIKELRELILSLRD--QGITVLISSHLLSEIQKVADRIGIINKGKLIEEG 208
|
|
| AztA |
NF040873 |
zinc ABC transporter ATP-binding protein AztA; |
21-217 |
4.46e-21 |
|
zinc ABC transporter ATP-binding protein AztA;
Pssm-ID: 468810 [Multi-domain] Cd Length: 191 Bit Score: 87.67 E-value: 4.46e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 21 LKNINWSLHSGENWVLMGLNGAGKTTLLSLIYGNHWATTGSIEVlgetfgktnvlALKKRIGLI--STAVQSQFPEHhlA 98
Cdd:NF040873 8 LHGVDLTIPAGSLTAVVGPNGSGKSTLLKVLAGVLRPTSGTVRR-----------AGGARVAYVpqRSEVPDSLPLT--V 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 99 QYIVLSGKFGTIGIHNDFEKNDLNEAIGLLKKLGGDELVNKPYRVLSQGQRQLVLIARALLGKPELLILDEPCNGLDLFS 178
Cdd:NF040873 75 RDLVAMGRWARRGLWRRLTRDDRAAVDDALERVGLADLAGRQLGELSGGQRQRALLAQGLAQEADLLLLDEPTTGLDAES 154
|
170 180 190
....*....|....*....|....*....|....*....
gi 915796356 179 RELLLEQINKLAQlpNHPTLLFVSHYTEEILPIFKNIML 217
Cdd:NF040873 155 RERIIALLAEEHA--RGATVVVVTHDLELVRRADPCVLL 191
|
|
| ABCC_Glucan_exporter_like |
cd03254 |
ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Glucan ... |
10-233 |
6.48e-21 |
|
ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Glucan exporter ATP-binding protein. In A. tumefaciens cyclic beta-1, 2-glucan must be transported into the periplasmic space to exert its action as a virulence factor. This subfamily belongs to the MRP-like family and is involved in drug, peptide, and lipid export. The MRP-like family, similar to all ABC proteins, have a common four-domain core structure constituted by two membrane-spanning domains each composed of six transmembrane (TM) helices and two nucleotide-binding domains (NBD). ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213221 [Multi-domain] Cd Length: 229 Bit Score: 88.05 E-value: 6.48e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 10 KNVSFERD--KIILKNINWSLHSGENWVLMGLNGAGKTTLLSLIYGNHWATTGSIEVLGETFGKTNVLALKKRIGLIsta 87
Cdd:cd03254 6 ENVNFSYDekKPVLKDINFSIKPGETVAIVGPTGAGKTTLINLLMRFYDPQKGQILIDGIDIRDISRKSLRSMIGVV--- 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 88 vqsqfpehhLAQYIVLSG------KFGTIGIHNDFEKNDLNEAIG--LLKKL--GGDELVNKPYRVLSQGQRQLVLIARA 157
Cdd:cd03254 83 ---------LQDTFLFSGtimeniRLGRPNATDEEVIEAAKEAGAhdFIMKLpnGYDTVLGENGGNLSQGERQLLAIARA 153
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 915796356 158 LLGKPELLILDEPCNGLDLFSRELLLEQINKLAqlpNHPTLLFVSHYteeiLPIFKN---IMLLKQGEIFAQGTRDKIL 233
Cdd:cd03254 154 MLRDPKILILDEATSNIDTETEKLIQEALEKLM---KGRTSIIIAHR----LSTIKNadkILVLDDGKIIEEGTHDELL 225
|
|
| cbiO |
PRK13641 |
energy-coupling factor transporter ATPase; |
17-242 |
9.86e-21 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 237456 [Multi-domain] Cd Length: 287 Bit Score: 88.73 E-value: 9.86e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 17 DKIILKNINWSLHSGENWVLMGLNGAGKTTLLSLIYGNHWATTGSIEVLGETF----GKTNVLALKKRIGLIStavqsQF 92
Cdd:PRK13641 19 EKKGLDNISFELEEGSFVALVGHTGSGKSTLMQHFNALLKPSSGTITIAGYHItpetGNKNLKKLRKKVSLVF-----QF 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 93 PEHHLAQYIVLSG-KFG--TIGIHNDFEKNdlnEAIGLLKKLG-GDELVNKPYRVLSQGQRQLVLIARALLGKPELLILD 168
Cdd:PRK13641 94 PEAQLFENTVLKDvEFGpkNFGFSEDEAKE---KALKWLKKVGlSEDLISKSPFELSGGQMRRVAIAGVMAYEPEILCLD 170
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 915796356 169 EPCNGLDLFSRELLLeQINKLAQLPNHpTLLFVSHYTEEILPIFKNIMLLKQGEIFAQGTRDKILTE-NVLSKFY 242
Cdd:PRK13641 171 EPAAGLDPEGRKEMM-QLFKDYQKAGH-TVILVTHNMDDVAEYADDVLVLEHGKLIKHASPKEIFSDkEWLKKHY 243
|
|
| ABC_NrtD_SsuB_transporters |
cd03293 |
ATP-binding cassette domain of the nitrate and sulfonate transporters; NrtD and SsuB are the ... |
7-207 |
1.14e-20 |
|
ATP-binding cassette domain of the nitrate and sulfonate transporters; NrtD and SsuB are the ATP-binding subunits of the bacterial ABC-type nitrate and sulfonate transport systems, respectively. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213260 [Multi-domain] Cd Length: 220 Bit Score: 87.14 E-value: 1.14e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 7 LSMKNVSF-----ERDKIILKNINWSLHSGENWVLMGLNGAGKTTLLSLIYGNHWATTGSIEVLGETfgktnVLALKKRI 81
Cdd:cd03293 1 LEVRNVSKtygggGGAVTALEDISLSVEEGEFVALVGPSGCGKSTLLRIIAGLERPTSGEVLVDGEP-----VTGPGPDR 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 82 GLIstavqsqFPEHHL------AQYIVLSGKFGTIGihndfeKNDLNE-AIGLLKKLGGDELVNKPYRVLSQGQRQLVLI 154
Cdd:cd03293 76 GYV-------FQQDALlpwltvLDNVALGLELQGVP------KAEARErAEELLELVGLSGFENAYPHQLSGGMRQRVAL 142
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 915796356 155 ARALLGKPELLILDEPCNGLDLFSRELLLEQINKLAQlPNHPTLLFVSHYTEE 207
Cdd:cd03293 143 ARALAVDPDVLLLDEPFSALDALTREQLQEELLDIWR-ETGKTVLLVTHDIDE 194
|
|
| ABCC_Protease_Secretion |
cd03246 |
ATP-binding cassette domain of PrtD, subfamily C; This family represents the ABC component of ... |
7-223 |
1.38e-20 |
|
ATP-binding cassette domain of PrtD, subfamily C; This family represents the ABC component of the protease secretion system PrtD, a 60-kDa integral membrane protein sharing 37% identity with HlyB, the ABC component of the alpha-hemolysin secretion pathway, in the C-terminal domain. They export degradative enzymes by using a type I protein secretion system and lack an N-terminal signal peptide, but contain a C-terminal secretion signal. The Type I secretion apparatus is made up of three components, an ABC transporter, a membrane fusion protein (MFP), and an outer membrane protein (OMP). For the HlyA transporter complex, HlyB (ABC transporter) and HlyD (MFP) reside in the inner membrane of E. coli. The OMP component is TolC, which is thought to interact with the MFP to form a continuous channel across the periplasm from the cytoplasm to the exterior. HlyB belongs to the family of ABC transporters, which are ubiquitous, ATP-dependent transmembrane pumps or channels. The spectrum of transport substrates ranges from inorganic ions, nutrients such as amino acids, sugars, or peptides, hydrophobic drugs, to large polypeptides, such as HlyA.
Pssm-ID: 213213 [Multi-domain] Cd Length: 173 Bit Score: 85.73 E-value: 1.38e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 7 LSMKNVSF---ERDKIILKNINWSLHSGENWVLMGLNGAGKTTLLSLIYGNHWATTGSIEVLGETFGKTNVLALKKRIGl 83
Cdd:cd03246 1 LEVENVSFrypGAEPPVLRNVSFSIEPGESLAIIGPSGSGKSTLARLILGLLRPTSGRVRLDGADISQWDPNELGDHVG- 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 84 istavqsqfpehHLAQYIVLSGkfGTIgihndfekndlNEAIgllkklggdelvnkpyrvLSQGQRQLVLIARALLGKPE 163
Cdd:cd03246 80 ------------YLPQDDELFS--GSI-----------AENI------------------LSGGQRQRLGLARALYGNPR 116
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 915796356 164 LLILDEPCNGLDLFSRELLLEQInklAQLP-NHPTLLFVSHyTEEILPIFKNIMLLKQGEI 223
Cdd:cd03246 117 ILVLDEPNSHLDVEGERALNQAI---AALKaAGATRIVIAH-RPETLASADRILVLEDGRV 173
|
|
| cbiO |
PRK13635 |
energy-coupling factor ABC transporter ATP-binding protein; |
1-232 |
1.39e-20 |
|
energy-coupling factor ABC transporter ATP-binding protein;
Pssm-ID: 184195 [Multi-domain] Cd Length: 279 Bit Score: 88.15 E-value: 1.39e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 1 MTNNaVLSMKNVSF---ERDKIILKNINWSLHSGEnWV-LMGLNGAGKTTLLSLIYGNHWATTGSIEVLGETFGKTNVLA 76
Cdd:PRK13635 1 MKEE-IIRVEHISFrypDAATYALKDVSFSVYEGE-WVaIVGHNGSGKSTLAKLLNGLLLPEAGTITVGGMVLSEETVWD 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 77 LKKRIGLISTAVQSQFPEHHLAQYIVlsgkFG--TIGIHNDFEKNDLNEAiglLKKLGGDELVNK-PYRvLSQGQRQLVL 153
Cdd:PRK13635 79 VRRQVGMVFQNPDNQFVGATVQDDVA----FGleNIGVPREEMVERVDQA---LRQVGMEDFLNRePHR-LSGGQKQRVA 150
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 915796356 154 IARALLGKPELLILDEPCNGLDLFSRELLLEQINKLAQLPNhPTLLFVSHYTEEILPIFKnIMLLKQGEIFAQGTRDKI 232
Cdd:PRK13635 151 IAGVLALQPDIIILDEATSMLDPRGRREVLETVRQLKEQKG-ITVLSITHDLDEAAQADR-VIVMNKGEILEEGTPEEI 227
|
|
| CeuD |
COG4604 |
ABC-type enterochelin transport system, ATPase component [Inorganic ion transport and ... |
8-259 |
1.90e-20 |
|
ABC-type enterochelin transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 443654 [Multi-domain] Cd Length: 252 Bit Score: 87.45 E-value: 1.90e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 8 SMKNVSFE-RDKIILKNINWSLHSGENWVLMGLNGAGKTTLLSLIYGNHWATTGSIEVLGETFGKTNVLALKKRIglist 86
Cdd:COG4604 3 EIKNVSKRyGGKVVLDDVSLTIPKGGITALIGPNGAGKSTLLSMISRLLPPDSGEVLVDGLDVATTPSRELAKRL----- 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 87 AVQSQfpEHHLA-----QYIVLSGKF----GTIGIhNDFEKndLNEAIGLlkkLGGDELVNKPYRVLSQGQRQLVLIARA 157
Cdd:COG4604 78 AILRQ--ENHINsrltvRELVAFGRFpyskGRLTA-EDREI--IDEAIAY---LDLEDLADRYLDELSGGQRQRAFIAMV 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 158 LLGKPELLILDEPCNGLDLF-SRElLLEQINKLAQLPNHPTLL------FVSHYTEeilpifkNIMLLKQGEIFAQGTRD 230
Cdd:COG4604 150 LAQDTDYVLLDEPLNNLDMKhSVQ-MMKLLRRLADELGKTVVIvlhdinFASCYAD-------HIVAMKDGRVVAQGTPE 221
|
250 260
....*....|....*....|....*....
gi 915796356 231 KILTENVLSKFYPKPIKIFPVTNNRFAVY 259
Cdd:COG4604 222 EIITPEVLSDIYDTDIEVEEIDGKRICVY 250
|
|
| ABCG_EPDR |
cd03213 |
Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette ... |
5-227 |
2.84e-20 |
|
Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette superfamily; ABCG transporters are involved in eye pigment (EP) precursor transport, regulation of lipid-trafficking mechanisms, and pleiotropic drug resistance (DR). DR is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. Compared to other members of the ABC transporter subfamilies, the ABCG transporter family is composed of proteins that have an ATP-binding cassette domain at the N-terminus and a TM (transmembrane) domain at the C-terminus.
Pssm-ID: 213180 [Multi-domain] Cd Length: 194 Bit Score: 85.68 E-value: 2.84e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 5 AVLSMKNVSFERD-------KIILKNINWSLHSGENWVLMGLNGAGKTTLLSLI--YGNHWATTGSIEVLGETFGKTNvl 75
Cdd:cd03213 2 VTLSFRNLTVTVKsspsksgKQLLKNVSGKAKPGELTAIMGPSGAGKSTLLNALagRRTGLGVSGEVLINGRPLDKRS-- 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 76 aLKKRIGLIstaVQSqfpEHHLAQYIVlsgkfgtigihndfekndlNEAIGLLKKLggdelvnkpyRVLSQGQRQLVLIA 155
Cdd:cd03213 80 -FRKIIGYV---PQD---DILHPTLTV-------------------RETLMFAAKL----------RGLSGGERKRVSIA 123
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 915796356 156 RALLGKPELLILDEPCNGLDLFSRELLLEQINKLAQlpNHPTLLFVSHY-TEEILPIFKNIMLLKQGEIFAQG 227
Cdd:cd03213 124 LELVSNPSLLFLDEPTSGLDSSSALQVMSLLRRLAD--TGRTIICSIHQpSSEIFELFDKLLLLSQGRVIYFG 194
|
|
| ABC_DrrA |
cd03265 |
Daunorubicin/doxorubicin resistance ATP-binding protein; DrrA is the ATP-binding protein ... |
21-228 |
2.92e-20 |
|
Daunorubicin/doxorubicin resistance ATP-binding protein; DrrA is the ATP-binding protein component of a bacterial exporter complex that confers resistance to the antibiotics daunorubicin and doxorubicin. In addition to DrrA, the complex includes an integral membrane protein called DrrB. DrrA belongs to the ABC family of transporters and shares sequence and functional similarities with a protein found in cancer cells called P-glycoprotein. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region in addition to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213232 [Multi-domain] Cd Length: 220 Bit Score: 86.27 E-value: 2.92e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 21 LKNINWSLHSGENWVLMGLNGAGKTTLLSLIYGNHWATTGSIEVLGETFGK--TNVlalKKRIGLIStavQSQFPEHHLA 98
Cdd:cd03265 16 VRGVSFRVRRGEIFGLLGPNGAGKTTTIKMLTTLLKPTSGRATVAGHDVVRepREV---RRRIGIVF---QDLSVDDELT 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 99 QY--IVLSGKFgtIGIHNDFEKNDLNEaigLLKKLGGDELVNKPYRVLSQGQRQLVLIARALLGKPELLILDEPCNGLDL 176
Cdd:cd03265 90 GWenLYIHARL--YGVPGAERRERIDE---LLDFVGLLEAADRLVKTYSGGMRRRLEIARSLVHRPEVLFLDEPTIGLDP 164
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 915796356 177 FSRELLLEQINKLaQLPNHPTLLFVSHYTEEILPIFKNIMLLKQGEIFAQGT 228
Cdd:cd03265 165 QTRAHVWEYIEKL-KEEFGMTILLTTHYMEEAEQLCDRVAIIDHGRIIAEGT 215
|
|
| PRK14246 |
PRK14246 |
phosphate ABC transporter ATP-binding protein; Provisional |
17-242 |
2.94e-20 |
|
phosphate ABC transporter ATP-binding protein; Provisional
Pssm-ID: 172734 [Multi-domain] Cd Length: 257 Bit Score: 87.02 E-value: 2.94e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 17 DKIILKNINWSLHSGENWVLMGLNGAGKTTLLSL------IYGNHWATTGSIEVLGETFGKTNVLALKKRIGLIstaVQS 90
Cdd:PRK14246 22 DKAILKDITIKIPNNSIFGIMGPSGSGKSTLLKVlnrlieIYDSKIKVDGKVLYFGKDIFQIDAIKLRKEVGMV---FQQ 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 91 QFPEHHLAQYIVLSGKFGTIGIHNDFEKNDLNE----AIGLLKKLggDELVNKPYRVLSQGQRQLVLIARALLGKPELLI 166
Cdd:PRK14246 99 PNPFPHLSIYDNIAYPLKSHGIKEKREIKKIVEeclrKVGLWKEV--YDRLNSPASQLSGGQQQRLTIARALALKPKVLL 176
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 915796356 167 LDEPCNGLDLFSRelllEQINKL-AQLPNHPTLLFVSHYTEEILPIFKNIMLLKQGEIFAQGTRDKILT--ENVLSKFY 242
Cdd:PRK14246 177 MDEPTSMIDIVNS----QAIEKLiTELKNEIAIVIVSHNPQQVARVADYVAFLYNGELVEWGSSNEIFTspKNELTEKY 251
|
|
| TauB |
COG1116 |
ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion ... |
1-203 |
3.43e-20 |
|
ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 440733 [Multi-domain] Cd Length: 260 Bit Score: 86.68 E-value: 3.43e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 1 MTNN-AVLSMKNVSF-----ERDKIILKNINWSLHSGENWVLMGLNGAGKTTLLSLIYGNHWATTGSIEVLGETfgktnV 74
Cdd:COG1116 1 MSAAaPALELRGVSKrfptgGGGVTALDDVSLTVAAGEFVALVGPSGCGKSTLLRLIAGLEKPTSGEVLVDGKP-----V 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 75 LALKKRIGLIstavqsqFPEHHL------AQYIVLSGKFGTIGIHNDFEKndlneAIGLLKKLGGDELVNK-PYRvLSQG 147
Cdd:COG1116 76 TGPGPDRGVV-------FQEPALlpwltvLDNVALGLELRGVPKAERRER-----ARELLELVGLAGFEDAyPHQ-LSGG 142
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 915796356 148 QRQLVLIARALLGKPELLILDEPCNGLDLFSRELLLEQINKLAQLpNHPTLLFVSH 203
Cdd:COG1116 143 MRQRVAIARALANDPEVLLMDEPFGALDALTRERLQDELLRLWQE-TGKTVLFVTH 197
|
|
| MglA |
COG1129 |
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; |
6-238 |
3.58e-20 |
|
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];
Pssm-ID: 440745 [Multi-domain] Cd Length: 497 Bit Score: 89.31 E-value: 3.58e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 6 VLSMKNVSFERdkiILKNINWSLHSGEnwVL--MGLNGAGKTTLLSLIYGNHWATTGSIEVLGETFGKTNVL-ALKKRIG 82
Cdd:COG1129 256 VLEVEGLSVGG---VVRDVSFSVRAGE--ILgiAGLVGAGRTELARALFGADPADSGEIRLDGKPVRIRSPRdAIRAGIA 330
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 83 LISTAVQSQ--FPEHHLAQYIVLS--GKFGTIG-IHNDFEKNDLNEAIGLLK-KLGGdelVNKPYRVLSQGQRQLVLIAR 156
Cdd:COG1129 331 YVPEDRKGEglVLDLSIRENITLAslDRLSRGGlLDRRRERALAEEYIKRLRiKTPS---PEQPVGNLSGGNQQKVVLAK 407
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 157 ALLGKPELLILDEPCNGLDLFSRELLLEQINKLAQ--LpnhpTLLFVSHYTEEILPIFKNIMLLKQGEIFAQGTRDKILT 234
Cdd:COG1129 408 WLATDPKVLILDEPTRGIDVGAKAEIYRLIRELAAegK----AVIVISSELPELLGLSDRILVMREGRIVGELDREEATE 483
|
....
gi 915796356 235 ENVL 238
Cdd:COG1129 484 EAIM 487
|
|
| cbiO |
PRK13634 |
cobalt transporter ATP-binding subunit; Provisional |
10-228 |
4.54e-20 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 237454 [Multi-domain] Cd Length: 290 Bit Score: 87.00 E-value: 4.54e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 10 KNVSFERDKiiLKNINWSLHSGENWVLMGLNGAGKTTLLSLIYGNHWATTGSIEvLGE---TFGKTN--VLALKKRIGLI 84
Cdd:PRK13634 14 YKTPFERRA--LYDVNVSIPSGSYVAIIGHTGSGKSTLLQHLNGLLQPTSGTVT-IGErviTAGKKNkkLKPLRKKVGIV 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 85 StavqsQFPEHHLAQYIVLSG-KFGTI--GIHNDFEKNDLNEAIGLLKkLGGDELVNKPYRvLSQGQRQLVLIARALLGK 161
Cdd:PRK13634 91 F-----QFPEHQLFEETVEKDiCFGPMnfGVSEEDAKQKAREMIELVG-LPEELLARSPFE-LSGGQMRRVAIAGVLAME 163
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 915796356 162 PELLILDEPCNGLDLFSRELLLEQINKLAQLPNHPTLLfVSHYTEEILPIFKNIMLLKQGEIFAQGT 228
Cdd:PRK13634 164 PEVLVLDEPTAGLDPKGRKEMMEMFYKLHKEKGLTTVL-VTHSMEDAARYADQIVVMHKGTVFLQGT 229
|
|
| ABC_Mj1267_LivG_branched |
cd03219 |
ATP-binding cassette component of branched chain amino acids transport system; The Mj1267/LivG ... |
21-234 |
5.55e-20 |
|
ATP-binding cassette component of branched chain amino acids transport system; The Mj1267/LivG ABC transporter subfamily is involved in the transport of the hydrophobic amino acids leucine, isoleucine and valine. MJ1267 is a branched-chain amino acid transporter with 29% similarity to both the LivF and LivG components of the E. coli branched-chain amino acid transporter. MJ1267 contains an insertion from residues 114 to 123 characteristic of LivG (Leucine-Isoleucine-Valine) homologs. The branched-chain amino acid transporter from E. coli comprises a heterodimer of ABCs (LivF and LivG), a heterodimer of six-helix TM domains (LivM and LivH), and one of two alternative soluble periplasmic substrate binding proteins (LivK or LivJ).
Pssm-ID: 213186 [Multi-domain] Cd Length: 236 Bit Score: 85.57 E-value: 5.55e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 21 LKNINWSLHSGENWVLMGLNGAGKTTLLSLIYGNHWATTGSIEVLGE-----------------TFGKTNVLAlkkriGL 83
Cdd:cd03219 16 LDDVSFSVRPGEIHGLIGPNGAGKTTLFNLISGFLRPTSGSVLFDGEditglppheiarlgigrTFQIPRLFP-----EL 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 84 -----ISTAVQSQfpehhlaqyivlSGKFGTIGIHNDFEKNDLNEAIGLLKKLGGDELVNKPYRVLSQGQRQLVLIARAL 158
Cdd:cd03219 91 tvlenVMVAAQAR------------TGSGLLLARARREEREARERAEELLERVGLADLADRPAGELSYGQQRRLEIARAL 158
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 915796356 159 LGKPELLILDEPCNGLDLFSRELLLEQINKLAQlpNHPTLLFVSHYTEEILPIFKNIMLLKQGEIFAQGTRDKILT 234
Cdd:cd03219 159 ATDPKLLLLDEPAAGLNPEETEELAELIRELRE--RGITVLLVEHDMDVVMSLADRVTVLDQGRVIAEGTPDEVRN 232
|
|
| potA |
PRK09452 |
spermidine/putrescine ABC transporter ATP-binding protein PotA; |
1-228 |
5.80e-20 |
|
spermidine/putrescine ABC transporter ATP-binding protein PotA;
Pssm-ID: 236523 [Multi-domain] Cd Length: 375 Bit Score: 87.70 E-value: 5.80e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 1 MTNNAVLSMKNV--SFErDKIILKNINWSLHSGENWVLMGLNGAGKTTLLSLIYGNHWATTGSIEVLGETFgkTNVLALK 78
Cdd:PRK09452 9 SSLSPLVELRGIskSFD-GKEVISNLDLTINNGEFLTLLGPSGCGKTTVLRLIAGFETPDSGRIMLDGQDI--THVPAEN 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 79 KRIgliSTAVQSQ--FPehHLaqyivlsgkfgTIgihndFEkndlNEAIGL-LKKLGGDE----------LVN------- 138
Cdd:PRK09452 86 RHV---NTVFQSYalFP--HM-----------TV-----FE----NVAFGLrMQKTPAAEitprvmealrMVQleefaqr 140
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 139 KPYRvLSQGQRQLVLIARALLGKPELLILDEPCNGLDLfsrELLLEQINKLAQLPNH--PTLLFVSHYTEEILPIFKNIM 216
Cdd:PRK09452 141 KPHQ-LSGGQQQRVAIARAVVNKPKVLLLDESLSALDY---KLRKQMQNELKALQRKlgITFVFVTHDQEEALTMSDRIV 216
|
250
....*....|..
gi 915796356 217 LLKQGEIFAQGT 228
Cdd:PRK09452 217 VMRDGRIEQDGT 228
|
|
| ABC_MalK_N |
cd03301 |
The N-terminal ATPase domain of the maltose transporter, MalK; ATP binding cassette (ABC) ... |
7-223 |
6.15e-20 |
|
The N-terminal ATPase domain of the maltose transporter, MalK; ATP binding cassette (ABC) proteins function from bacteria to human, mediating the translocation of substances into and out of cells or organelles. ABC transporters contain two transmembrane-spanning domains (TMDs) or subunits and two nucleotide binding domains (NBDs) or subunits that couple transport to the hydrolysis of ATP. In the maltose transport system, the periplasmic maltose binding protein (MBP) stimulates the ATPase activity of the membrane-associated transporter, which consists of two transmembrane subunits, MalF and MalG, and two copies of the ATP binding subunit, MalK, and becomes tightly bound to the transporter in the catalytic transition state, ensuring that maltose is passed to the transporter as ATP is hydrolyzed.
Pssm-ID: 213268 [Multi-domain] Cd Length: 213 Bit Score: 85.00 E-value: 6.15e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 7 LSMKNV--SFErDKIILKNINWSLHSGENWVLMGLNGAGKTTLLSLIYGNHWATTGSIEVLGETFgkTNVLALKKRIGLI 84
Cdd:cd03301 1 VELENVtkRFG-NVTALDDLNLDIADGEFVVLLGPSGCGKTTTLRMIAGLEEPTSGRIYIGGRDV--TDLPPKDRDIAMV 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 85 --STAVqsqFPEHHLAQYIVLSGKFgtigihNDFEKNDLNEAI-GLLKKLGGDELVNKPYRVLSQGQRQLVLIARALLGK 161
Cdd:cd03301 78 fqNYAL---YPHMTVYDNIAFGLKL------RKVPKDEIDERVrEVAELLQIEHLLDRKPKQLSGGQRQRVALGRAIVRE 148
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 915796356 162 PELLILDEPCNGLDLFSRELLLEQINKLAQLPNHpTLLFVSHYTEEILPIFKNIMLLKQGEI 223
Cdd:cd03301 149 PKVFLMDEPLSNLDAKLRVQMRAELKRLQQRLGT-TTIYVTHDQVEAMTMADRIAVMNDGQI 209
|
|
| BtuD |
COG4138 |
ABC-type cobalamin transport system, ATPase component BtuD [Coenzyme transport and metabolism]; ... |
31-255 |
9.81e-20 |
|
ABC-type cobalamin transport system, ATPase component BtuD [Coenzyme transport and metabolism];
Pssm-ID: 443313 [Multi-domain] Cd Length: 248 Bit Score: 85.28 E-value: 9.81e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 31 GENWVLMGLNGAGKTTLLSLIYGNHwATTGSIEVLGETFGKTNVLALKKRIGLIStavQSQFPEHHLA--QYIVLSGKFG 108
Cdd:COG4138 22 GELIHLIGPNGAGKSTLLARMAGLL-PGQGEILLNGRPLSDWSAAELARHRAYLS---QQQSPPFAMPvfQYLALHQPAG 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 109 TIGIHNDFEKNDLNEAIGLLKKLGgdelvnKPYRVLSQGQRQLVLIARALL-----GKPE--LLILDEPCNGLDLFSREL 181
Cdd:COG4138 98 ASSEAVEQLLAQLAEALGLEDKLS------RPLTQLSGGEWQRVRLAAVLLqvwptINPEgqLLLLDEPMNSLDVAQQAA 171
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 182 LLEQINKLAQLP----------NHpTLLFVSHyteeilpifknIMLLKQGEIFAQGTRDKILTENVLSKFYPKPIKIFPV 251
Cdd:COG4138 172 LDRLLRELCQQGitvvmsshdlNH-TLRHADR-----------VWLLKQGKLVASGETAEVMTPENLSEVFGVKFRRLEV 239
|
....
gi 915796356 252 TNNR 255
Cdd:COG4138 240 EGHR 243
|
|
| araG |
PRK11288 |
L-arabinose ABC transporter ATP-binding protein AraG; |
21-237 |
1.30e-19 |
|
L-arabinose ABC transporter ATP-binding protein AraG;
Pssm-ID: 183077 [Multi-domain] Cd Length: 501 Bit Score: 87.66 E-value: 1.30e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 21 LKNINWSLHSGENWVLMGLNGAGKTTLLSLIYGNHWATTGSIEVLGETFGKTNVL-ALKKRIGLISTAVQsQFPEHHLAQ 99
Cdd:PRK11288 20 LDDISFDCRAGQVHALMGENGAGKSTLLKILSGNYQPDAGSILIDGQEMRFASTTaALAAGVAIIYQELH-LVPEMTVAE 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 100 YIVLS---GKFGTIgihndfEKNDLN-EAIGLLKKLGGDELVNKPYRVLSQGQRQLVLIARALLGKPELLILDEPCNGLD 175
Cdd:PRK11288 99 NLYLGqlpHKGGIV------NRRLLNyEAREQLEHLGVDIDPDTPLKYLSIGQRQMVEIAKALARNARVIAFDEPTSSLS 172
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 176 lfSREL--LLEQINKLAQlpNHPTLLFVSHYTEEILPIFKNIMLLKQG------EIFAQGTRDKILTENV 237
Cdd:PRK11288 173 --AREIeqLFRVIRELRA--EGRVILYVSHRMEEIFALCDAITVFKDGryvatfDDMAQVDRDQLVQAMV 238
|
|
| ABC_Carb_Monos_II |
cd03215 |
Second domain of the ATP-binding cassette component of monosaccharide transport system; This ... |
5-223 |
1.55e-19 |
|
Second domain of the ATP-binding cassette component of monosaccharide transport system; This family represents domain II of the carbohydrate uptake proteins that transport only monosaccharides (Monos). The Carb_Monos family is involved in the uptake of monosaccharides, such as pentoses (such as xylose, arabinose, and ribose) and hexoses (such as xylose, arabinose, and ribose), that cannot be broken down to simple sugars by hydrolysis. In members of Carb_Monos family the single hydrophobic gene product forms a homodimer, while the ABC protein represents a fusion of two nucleotide-binding domains. However, it is assumed that two copies of the ABC domains are present in the assembled transporter.
Pssm-ID: 213182 [Multi-domain] Cd Length: 182 Bit Score: 83.25 E-value: 1.55e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 5 AVLSMKNVSFerdKIILKNINWSLHSGENWVLMGLNGAGKTTLLSLIYGNHWATTGSIEVLGETFGKTNVL-ALKKRIGL 83
Cdd:cd03215 3 PVLEVRGLSV---KGAVRDVSFEVRAGEIVGIAGLVGNGQTELAEALFGLRPPASGEITLDGKPVTRRSPRdAIRAGIAY 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 84 IstavqsqfPEHHLAQYIVLSgkFGTIGihndfekndlNEAIGLLkklggdelvnkpyrvLSQGQRQLVLIARALLGKPE 163
Cdd:cd03215 80 V--------PEDRKREGLVLD--LSVAE----------NIALSSL---------------LSGGNQQKVVLARWLARDPR 124
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 164 LLILDEPCNGLDLFSRELLLEQINKLAQlpNHPTLLFVSHYTEEILPIFKNIMLLKQGEI 223
Cdd:cd03215 125 VLILDEPTRGVDVGAKAEIYRLIRELAD--AGKAVLLISSELDELLGLCDRILVMYEGRI 182
|
|
| ABC_PstB_phosphate_transporter |
cd03260 |
ATP-binding cassette domain of the phosphate transport system; Phosphate uptake is of ... |
7-232 |
1.94e-19 |
|
ATP-binding cassette domain of the phosphate transport system; Phosphate uptake is of fundamental importance in the cell physiology of bacteria because phosphate is required as a nutrient. The Pst system of E. coli comprises four distinct subunits encoded by the pstS, pstA, pstB, and pstC genes. The PstS protein is a phosphate-binding protein located in the periplasmic space. PstA and PstC are hydrophobic and they form the transmembrane portion of the Pst system. PstB is the catalytic subunit, which couples the energy of ATP hydrolysis to the import of phosphate across cellular membranes through the Pst system, often referred as ABC-protein. PstB belongs to one of the largest superfamilies of proteins characterized by a highly conserved adenosine triphosphate (ATP) binding cassette (ABC), which is also a nucleotide binding domain (NBD).
Pssm-ID: 213227 [Multi-domain] Cd Length: 227 Bit Score: 84.15 E-value: 1.94e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 7 LSMKNVSFER-DKIILKNINWSLHSGENWVLMGLNGAGKTTLLSLIYGNHWA-----TTGSIEVLGETF--GKTNVLALK 78
Cdd:cd03260 1 IELRDLNVYYgDKHALKDISLDIPKGEITALIGPSGCGKSTLLRLLNRLNDLipgapDEGEVLLDGKDIydLDVDVLELR 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 79 KRIGLIstaVQSQFPEHhlaqyivlsgkfGTI-----------GIHNDFEKNDLNEAigLLKKLGGDELVNKP--YRVLS 145
Cdd:cd03260 81 RRVGMV---FQKPNPFP------------GSIydnvayglrlhGIKLKEELDERVEE--ALRKAALWDEVKDRlhALGLS 143
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 146 QGQRQLVLIARALLGKPELLILDEPCNGLDLFSRELLLEQINKLAQlpnHPTLLFVSHYTEEILPIFKNIMLLKQGEIFA 225
Cdd:cd03260 144 GGQQQRLCLARALANEPEVLLLDEPTSALDPISTAKIEELIAELKK---EYTIVIVTHNMQQAARVADRTAFLLNGRLVE 220
|
....*..
gi 915796356 226 QGTRDKI 232
Cdd:cd03260 221 FGPTEQI 227
|
|
| YhaQ |
COG4152 |
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ... |
6-232 |
2.16e-19 |
|
ABC-type uncharacterized transport system, ATPase component [General function prediction only];
Pssm-ID: 443322 [Multi-domain] Cd Length: 298 Bit Score: 85.16 E-value: 2.16e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 6 VLSMKNV--SFErDKIILKNINWSLHSGEnwvLMGL---NGAGKTTLLSLIYGNHWATTGSIEVLGETFGKTNVlalkKR 80
Cdd:COG4152 1 MLELKGLtkRFG-DKTAVDDVSFTVPKGE---IFGLlgpNGAGKTTTIRIILGILAPDSGEVLWDGEPLDPEDR----RR 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 81 IGLIstavqsqfPE--------------HHLAQyivLSGkfgtigihndFEKNDLNEAI-GLLKKLGGDELVNKPYRVLS 145
Cdd:COG4152 73 IGYL--------PEerglypkmkvgeqlVYLAR---LKG----------LSKAEAKRRAdEWLERLGLGDRANKKVEELS 131
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 146 QGQRQLVLIARALLGKPELLILDEPCNGLDLFSRELLLEQINKLAQlpNHPTLLFVSH---YTEEILpifKNIMLLKQGE 222
Cdd:COG4152 132 KGNQQKVQLIAALLHDPELLILDEPFSGLDPVNVELLKDVIRELAA--KGTTVIFSSHqmeLVEELC---DRIVIINKGR 206
|
250
....*....|
gi 915796356 223 IFAQGTRDKI 232
Cdd:COG4152 207 KVLSGSVDEI 216
|
|
| ABC_TM1139_LivF_branched |
cd03224 |
ATP-binding cassette domain of branched-chain amino acid transporter; LivF (TM1139) is part of ... |
20-235 |
2.53e-19 |
|
ATP-binding cassette domain of branched-chain amino acid transporter; LivF (TM1139) is part of the LIV-I bacterial ABC-type two-component transport system that imports neutral, branched-chain amino acids. The E. coli branched-chain amino acid transporter comprises a heterodimer of ABC transporters (LivF and LivG), a heterodimer of six-helix TM domains (LivM and LivH), and one of two alternative soluble periplasmic substrate binding proteins (LivK or LivJ). ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules.
Pssm-ID: 213191 [Multi-domain] Cd Length: 222 Bit Score: 83.64 E-value: 2.53e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 20 ILKNINWSLHSGENWVLMGLNGAGKTTLLSLIYGNHWATTGSIEVLGETFGKTNVLALKKR-IGLIStavQSQ--FPEHH 96
Cdd:cd03224 15 ILFGVSLTVPEGEIVALLGRNGAGKTTLLKTIMGLLPPRSGSIRFDGRDITGLPPHERARAgIGYVP---EGRriFPELT 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 97 LAQYIVLSGKFGtigiHNDFEKNDLNEAIGLLKKLggDELVNKPYRVLSQGQRQLVLIARALLGKPELLILDEPCNGLD- 175
Cdd:cd03224 92 VEENLLLGAYAR----RRAKRKARLERVYELFPRL--KERRKQLAGTLSGGEQQMLAIARALMSRPKLLLLDEPSEGLAp 165
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 915796356 176 LFSRELL--LEQINKLAQlpnhpTLLFVSHYTEEILPIFKNIMLLKQGEIFAQGTRDKILTE 235
Cdd:cd03224 166 KIVEEIFeaIRELRDEGV-----TILLVEQNARFALEIADRAYVLERGRVVLEGTAAELLAD 222
|
|
| fbpC |
PRK11432 |
ferric ABC transporter ATP-binding protein; |
1-228 |
2.72e-19 |
|
ferric ABC transporter ATP-binding protein;
Pssm-ID: 183133 [Multi-domain] Cd Length: 351 Bit Score: 85.93 E-value: 2.72e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 1 MTNNAVLSMKNV--SFERDKIIlKNINWSLHSGENWVLMGLNGAGKTTLLSLIYGNHWATTGSIEVLGETFGKTnvlALK 78
Cdd:PRK11432 1 MTQKNFVVLKNItkRFGSNTVI-DNLNLTIKQGTMVTLLGPSGCGKTTVLRLVAGLEKPTEGQIFIDGEDVTHR---SIQ 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 79 KRIglISTAVQSQ--FPEHHLAQYIVLSGKFgtIGIHNDFEKNDLNEAIGLLKKLG-GDELVNKpyrvLSQGQRQLVLIA 155
Cdd:PRK11432 77 QRD--ICMVFQSYalFPHMSLGENVGYGLKM--LGVPKEERKQRVKEALELVDLAGfEDRYVDQ----ISGGQQQRVALA 148
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 915796356 156 RALLGKPELLILDEPCNGLDLFSRELLLEQINKLAQLPNhPTLLFVSHYTEEILPIFKNIMLLKQGEIFAQGT 228
Cdd:PRK11432 149 RALILKPKVLLFDEPLSNLDANLRRSMREKIRELQQQFN-ITSLYVTHDQSEAFAVSDTVIVMNKGKIMQIGS 220
|
|
| ABCC_NFT1 |
cd03369 |
ATP-binding cassette domain 2 of NFT1, subfamily C; Domain 2 of NFT1 (New full-length MRP-type ... |
20-223 |
3.29e-19 |
|
ATP-binding cassette domain 2 of NFT1, subfamily C; Domain 2 of NFT1 (New full-length MRP-type transporter 1). NFT1 belongs to the MRP (multidrug resistance-associated protein) family of ABC transporters. Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resisting lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions such as glutathione, glucuronate, and sulfate.
Pssm-ID: 213269 [Multi-domain] Cd Length: 207 Bit Score: 82.85 E-value: 3.29e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 20 ILKNINWSLHSGENWVLMGLNGAGKTTLLSLIYGNHWATTGSIEVLGETFGKTNVLALKKRIGLIStavqsQFPehhlaq 99
Cdd:cd03369 23 VLKNVSFKVKAGEKIGIVGRTGAGKSTLILALFRFLEAEEGKIEIDGIDISTIPLEDLRSSLTIIP-----QDP------ 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 100 yIVLSGKFGT-IGIHNDFEKNDLNEAIGLlkKLGGDELvnkpyrvlSQGQRQLVLIARALLGKPELLILDEPCNGLDLFS 178
Cdd:cd03369 92 -TLFSGTIRSnLDPFDEYSDEEIYGALRV--SEGGLNL--------SQGQRQLLCLARALLKRPRVLVLDEATASIDYAT 160
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
gi 915796356 179 RELLLEQINKLAqlpNHPTLLFVSHYTEEILPiFKNIMLLKQGEI 223
Cdd:cd03369 161 DALIQKTIREEF---TNSTILTIAHRLRTIID-YDKILVMDAGEV 201
|
|
| modC |
PRK11144 |
molybdenum ABC transporter ATP-binding protein ModC; |
38-227 |
4.09e-19 |
|
molybdenum ABC transporter ATP-binding protein ModC;
Pssm-ID: 182993 [Multi-domain] Cd Length: 352 Bit Score: 85.31 E-value: 4.09e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 38 GLNGAGKTTLLSLIYGNHWATTGSI----EVLGETFGKTNVLALKKRIGLIstavqsqFPEHHL-AQYIVLSG-KFGTig 111
Cdd:PRK11144 31 GRSGAGKTSLINAISGLTRPQKGRIvlngRVLFDAEKGICLPPEKRRIGYV-------FQDARLfPHYKVRGNlRYGM-- 101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 112 ihNDFEKNDLNEAIGLLkklGGDELVNKPYRVLSQGQRQLVLIARALLGKPELLILDEPCNGLDL-FSRELL--LEqinK 188
Cdd:PRK11144 102 --AKSMVAQFDKIVALL---GIEPLLDRYPGSLSGGEKQRVAIGRALLTAPELLLMDEPLASLDLpRKRELLpyLE---R 173
|
170 180 190
....*....|....*....|....*....|....*....
gi 915796356 189 LAQLPNHPtLLFVSHYTEEILPIFKNIMLLKQGEIFAQG 227
Cdd:PRK11144 174 LAREINIP-ILYVSHSLDEILRLADRVVVLEQGKVKAFG 211
|
|
| ABC_ThiQ_thiamine_transporter |
cd03298 |
ATP-binding cassette domain of the thiamine transport system; Part of the ... |
19-227 |
4.23e-19 |
|
ATP-binding cassette domain of the thiamine transport system; Part of the binding-protein-dependent transport system tbpA-thiPQ for thiamine and TPP. Probably responsible for the translocation of thiamine across the membrane. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213265 [Multi-domain] Cd Length: 211 Bit Score: 82.93 E-value: 4.23e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 19 IILKNINWSLHS-----------GENWVLMGLNGAGKTTLLSLIYGNHWATTGSIEVLGETFGKTNVLAlkkriglisTA 87
Cdd:cd03298 1 VRLDKIRFSYGEqpmhfdltfaqGEITAIVGPSGSGKSTLLNLIAGFETPQSGRVLINGVDVTAAPPAD---------RP 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 88 VQSQFPEHHLAQYIVLSGKFGtIGIHNDFEKNDLN-EAI-GLLKKLGGDELVNKPYRVLSQGQRQLVLIARALLGKPELL 165
Cdd:cd03298 72 VSMLFQENNLFAHLTVEQNVG-LGLSPGLKLTAEDrQAIeVALARVGLAGLEKRLPGELSGGERQRVALARVLVRDKPVL 150
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 915796356 166 ILDEPCNGLDLFSRELLLEQINKL-AQLPNhpTLLFVSHYTEEILPIFKNIMLLKQGEIFAQG 227
Cdd:cd03298 151 LLDEPFAALDPALRAEMLDLVLDLhAETKM--TVLMVTHQPEDAKRLAQRVVFLDNGRIAAQG 211
|
|
| PRK10938 |
PRK10938 |
putative molybdenum transport ATP-binding protein ModF; Provisional |
28-240 |
5.22e-19 |
|
putative molybdenum transport ATP-binding protein ModF; Provisional
Pssm-ID: 182852 [Multi-domain] Cd Length: 490 Bit Score: 85.84 E-value: 5.22e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 28 LHSGENWVLMGLNGAGKTTLlsliygnhwattgsievlgetfgktnVLALKKRIGLISTAVQSQFpeHHLA-------QY 100
Cdd:PRK10938 26 LNAGDSWAFVGANGSGKSAL--------------------------ARALAGELPLLSGERQSQF--SHITrlsfeqlQK 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 101 IV-----------LS------GKFGTIGIHNDFEKNDLNEAigLLKKLGGDELVNKPYRVLSQGQRQLVLIARALLGKPE 163
Cdd:PRK10938 78 LVsdewqrnntdmLSpgeddtGRTTAEIIQDEVKDPARCEQ--LAQQFGITALLDRRFKYLSTGETRKTLLCQALMSEPD 155
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 915796356 164 LLILDEPCNGLDLFSRELLLEQINKLAQlpNHPTLLFVSHYTEEILPIFKNIMLLKQGEIFAQGTRDKILTENVLSK 240
Cdd:PRK10938 156 LLILDEPFDGLDVASRQQLAELLASLHQ--SGITLVLVLNRFDEIPDFVQFAGVLADCTLAETGEREEILQQALVAQ 230
|
|
| cbiO |
PRK13632 |
cobalt transporter ATP-binding subunit; Provisional |
2-235 |
9.89e-19 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 237452 [Multi-domain] Cd Length: 271 Bit Score: 83.12 E-value: 9.89e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 2 TNNAVLSMKNVSF---ERDKIILKNINWSLHSGENWVLMGLNGAGKTTLLSLIYGNHWATTGSIEVLGETFGKTNVLALK 78
Cdd:PRK13632 3 NKSVMIKVENVSFsypNSENNALKNVSFEINEGEYVAILGHNGSGKSTISKILTGLLKPQSGEIKIDGITISKENLKEIR 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 79 KRIGLIstavqSQFPEHhlaQYIVLSGK----FGTIGIHNDFEKndLNEAI-GLLKKLGGDELVNKPYRVLSQGQRQLVL 153
Cdd:PRK13632 83 KKIGII-----FQNPDN---QFIGATVEddiaFGLENKKVPPKK--MKDIIdDLAKKVGMEDYLDKEPQNLSGGQKQRVA 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 154 IARALLGKPELLILDEPCNGLDLFSRELLLEQINKLAQLPNHpTLLFVSHYTEEILPIFKnIMLLKQGEIFAQGTRDKIL 233
Cdd:PRK13632 153 IASVLALNPEIIIFDESTSMLDPKGKREIKKIMVDLRKTRKK-TLISITHDMDEAILADK-VIVFSEGKLIAQGKPKEIL 230
|
..
gi 915796356 234 TE 235
Cdd:PRK13632 231 NN 232
|
|
| MdlB |
COG1132 |
ABC-type multidrug transport system, ATPase and permease component [Defense mechanisms]; |
7-236 |
1.57e-18 |
|
ABC-type multidrug transport system, ATPase and permease component [Defense mechanisms];
Pssm-ID: 440747 [Multi-domain] Cd Length: 579 Bit Score: 84.45 E-value: 1.57e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 7 LSMKNVSF--ERDKIILKNINWSLHSGENWVLMGLNGAGKTTLLSLIYGNHWATTGSIEVLGETFGKTNVLALKKRIGLI 84
Cdd:COG1132 340 IEFENVSFsyPGDRPVLKDISLTIPPGETVALVGPSGSGKSTLVNLLLRFYDPTSGRILIDGVDIRDLTLESLRRQIGVV 419
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 85 StavqsQfpEHHLaqyivLSG------KFGTIGIHNDfeknDLNEAiglLKKLGGDELVNK-P----YRV------LSQG 147
Cdd:COG1132 420 P-----Q--DTFL-----FSGtireniRYGRPDATDE----EVEEA---AKAAQAHEFIEAlPdgydTVVgergvnLSGG 480
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 148 QRQLVLIARALLGKPELLILDEPCNGLDLFSRELLLEQINKLAQlpnHPTLLFVSHYTEEIlpifKN---IMLLKQGEIF 224
Cdd:COG1132 481 QRQRIAIARALLKDPPILILDEATSALDTETEALIQEALERLMK---GRTTIVIAHRLSTI----RNadrILVLDDGRIV 553
|
250
....*....|..
gi 915796356 225 AQGTRDKILTEN 236
Cdd:COG1132 554 EQGTHEELLARG 565
|
|
| cbiO |
PRK13647 |
cobalt transporter ATP-binding subunit; Provisional |
21-249 |
1.70e-18 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 237457 [Multi-domain] Cd Length: 274 Bit Score: 82.48 E-value: 1.70e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 21 LKNINWSLHSGENWVLMGLNGAGKTTLLSLIYGNHWATTGSIEVLGETFGKTNVLALKKRIGLIstavqSQFPEHHLAQY 100
Cdd:PRK13647 21 LKGLSLSIPEGSKTALLGPNGAGKSTLLLHLNGIYLPQRGRVKVMGREVNAENEKWVRSKVGLV-----FQDPDDQVFSS 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 101 IVLSG-KFGTI--GIHNDFEKNDLNEAiglLKKLGGDELVNKPYRVLSQGQRQLVLIARALLGKPELLILDEPCNGLDLF 177
Cdd:PRK13647 96 TVWDDvAFGPVnmGLDKDEVERRVEEA---LKAVRMWDFRDKPPYHLSYGQKKRVAIAGVLAMDPDVIVLDEPMAYLDPR 172
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 915796356 178 SRELLLEQINKLAQlpNHPTLLFVSHYTEEILPIFKNIMLLKQGEIFAQG-----TRDKILTENVLSkfYPKPIKIF 249
Cdd:PRK13647 173 GQETLMEILDRLHN--QGKTVIVATHDVDLAAEWADQVIVLKEGRVLAEGdksllTDEDIVEQAGLR--LPLVAQIF 245
|
|
| ABCC_ATM1_transporter |
cd03253 |
ATP-binding cassette domain of iron-sulfur clusters transporter, subfamily C; ATM1 is an ABC ... |
10-236 |
1.82e-18 |
|
ATP-binding cassette domain of iron-sulfur clusters transporter, subfamily C; ATM1 is an ABC transporter that is expressed in the mitochondria. Although the specific function of ATM1 is unknown, its disruption results in the accumulation of excess mitochondrial iron, loss of mitochondrial cytochromes, oxidative damage to mitochondrial DNA, and decreased levels of cytosolic heme proteins. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213220 [Multi-domain] Cd Length: 236 Bit Score: 81.51 E-value: 1.82e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 10 KNVSFERD--KIILKNINWSLHSGENWVLMGLNGAGKTTLLSLIYGNHWATTGSIEVLGETFGKTNVLALKKRIGLIsta 87
Cdd:cd03253 4 ENVTFAYDpgRPVLKDVSFTIPAGKKVAIVGPSGSGKSTILRLLFRFYDVSSGSILIDGQDIREVTLDSLRRAIGVV--- 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 88 vqsqfPehhlaQYIVLSG-------KFGTIGIHND-----FEKNDLNEAIGLLKKlGGDELVNKPYRVLSQGQRQLVLIA 155
Cdd:cd03253 81 -----P-----QDTVLFNdtigyniRYGRPDATDEevieaAKAAQIHDKIMRFPD-GYDTIVGERGLKLSGGEKQRVAIA 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 156 RALLGKPELLILDEPCNGLDLFSRELLLEQINKLAqlpNHPTLLFVSHYTEEILPIFKnIMLLKQGEIFAQGTRDKILTE 235
Cdd:cd03253 150 RAILKNPPILLLDEATSALDTHTEREIQAALRDVS---KGRTTIVIAHRLSTIVNADK-IIVLKDGRIVERGTHEELLAK 225
|
.
gi 915796356 236 N 236
Cdd:cd03253 226 G 226
|
|
| thiQ |
TIGR01277 |
thiamine ABC transporter, ATP-binding protein; This model describes the energy-transducing ... |
7-227 |
2.79e-18 |
|
thiamine ABC transporter, ATP-binding protein; This model describes the energy-transducing ATPase subunit ThiQ of the ThiBPQ thiamine (and thiamine pyrophosphate) ABC transporter in several Proteobacteria. This protein is found so far only in Proteobacteria, and is found in complete genomes only if the ThiB and ThiP subunits are also found. [Transport and binding proteins, Other]
Pssm-ID: 130344 [Multi-domain] Cd Length: 213 Bit Score: 80.68 E-value: 2.79e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 7 LSMKNVSFErDKIILKNINWSLHSGENWVLMGLNGAGKTTLLSLIYGNHWATTGSIEVLGETFGKTnvlALKKRiglist 86
Cdd:TIGR01277 1 LALDKVRYE-YEHLPMEFDLNVADGEIVAIMGPSGAGKSTLLNLIAGFIEPASGSIKVNDQSHTGL---APYQR------ 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 87 AVQSQFPEHHLAQYIVLSGKFGtIGIHNDFEKNDLNE--AIGLLKKLGGDELVNKPYRVLSQGQRQLVLIARALLGKPEL 164
Cdd:TIGR01277 71 PVSMLFQENNLFAHLTVRQNIG-LGLHPGLKLNAEQQekVVDAAQQVGIADYLDRLPEQLSGGQRQRVALARCLVRPNPI 149
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 915796356 165 LILDEPCNGLDLFSRELLLEQINKLAQlPNHPTLLFVSHYTEEILPIFKNIMLLKQGEIFAQG 227
Cdd:TIGR01277 150 LLLDEPFSALDPLLREEMLALVKQLCS-ERQRTLLMVTHHLSDARAIASQIAVVSQGKIKVVS 211
|
|
| ABCC_MsbA |
cd03251 |
ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; ... |
7-236 |
3.30e-18 |
|
ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; MsbA is an essential ABC transporter, closely related to eukaryotic MDR proteins. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213218 [Multi-domain] Cd Length: 234 Bit Score: 80.74 E-value: 3.30e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 7 LSMKNVSF---ERDKIILKNINWSLHSGENWVLMGLNGAGKTTLLSLIYGNHWATTGSIEVLGETFGKTNVLALKKRIGL 83
Cdd:cd03251 1 VEFKNVTFrypGDGPPVLRDISLDIPAGETVALVGPSGSGKSTLVNLIPRFYDVDSGRILIDGHDVRDYTLASLRRQIGL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 84 IStavqsqfpehhlaQYIVLsgkF-GTI------GIHNDFEKndlnEAIGLLKKLGGDELVNK-P--YRV--------LS 145
Cdd:cd03251 81 VS-------------QDVFL---FnDTVaeniayGRPGATRE----EVEEAARAANAHEFIMElPegYDTvigergvkLS 140
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 146 QGQRQLVLIARALLGKPELLILDEPCNGLDLFSRELLLEQINKLAQlpnHPTLLFVSHYTEEIlpifKN---IMLLKQGE 222
Cdd:cd03251 141 GGQRQRIAIARALLKDPPILILDEATSALDTESERLVQAALERLMK---NRTTFVIAHRLSTI----ENadrIVVLEDGK 213
|
250
....*....|....
gi 915796356 223 IFAQGTRDKILTEN 236
Cdd:cd03251 214 IVERGTHEELLAQG 227
|
|
| ABC_HisP_GlnQ |
cd03262 |
ATP-binding cassette domain of the histidine and glutamine transporters; HisP and GlnQ are the ... |
7-203 |
3.38e-18 |
|
ATP-binding cassette domain of the histidine and glutamine transporters; HisP and GlnQ are the ATP-binding components of the bacterial periplasmic histidine and glutamine permeases, respectively. Histidine permease is a multi-subunit complex containing the HisQ and HisM integral membrane subunits and two copies of HisP. HisP has properties intermediate between those of integral and peripheral membrane proteins and is accessible from both sides of the membrane, presumably by its interaction with HisQ and HisM. The two HisP subunits form a homodimer within the complex. The domain structure of the amino acid uptake systems is typical for prokaryotic extracellular solute binding protein-dependent uptake systems. All of the amino acid uptake systems also have at least one, and in a few cases, two extracellular solute binding proteins located in the periplasm of Gram-negative bacteria, or attached to the cell membrane of Gram-positive bacteria. The best-studied member of the PAAT (polar amino acid transport) family is the HisJQMP system of S. typhimurium, where HisJ is the extracellular solute binding proteins and HisP is the ABC protein.
Pssm-ID: 213229 [Multi-domain] Cd Length: 213 Bit Score: 80.27 E-value: 3.38e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 7 LSMKNV--SFErDKIILKNINWSLHSGENWVLMGLNGAGKTTLLSLIYGNHWATTGSIEVLGE--TFGKTNVLALKKRIG 82
Cdd:cd03262 1 IEIKNLhkSFG-DFHVLKGIDLTVKKGEVVVIIGPSGSGKSTLLRCINLLEEPDSGTIIIDGLklTDDKKNINELRQKVG 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 83 LIstaVQS--QFPEHHLAQYIVLsgkfGTIGIHNDFEKNDLNEAIGLLKKLGGDELVNKPYRVLSQGQRQLVLIARALLG 160
Cdd:cd03262 80 MV---FQQfnLFPHLTVLENITL----APIKVKGMSKAEAEERALELLEKVGLADKADAYPAQLSGGQQQRVAIARALAM 152
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 915796356 161 KPELLILDEPCNGLDlfsREL---LLEQINKLAQlpNHPTLLFVSH 203
Cdd:cd03262 153 NPKVMLFDEPTSALD---PELvgeVLDVMKDLAE--EGMTMVVVTH 193
|
|
| type_I_sec_PrtD |
TIGR01842 |
type I secretion system ABC transporter, PrtD family; Type I protein secretion is a system in ... |
4-235 |
3.68e-18 |
|
type I secretion system ABC transporter, PrtD family; Type I protein secretion is a system in some Gram-negative bacteria to export proteins (often proteases) across both inner and outer membranes to the extracellular medium. This is one of three proteins of the type I secretion apparatus. Targeted proteins are not cleaved at the N-terminus, but rather carry signals located toward the extreme C-terminus to direct type I secretion. [Protein fate, Protein and peptide secretion and trafficking]
Pssm-ID: 200134 [Multi-domain] Cd Length: 544 Bit Score: 83.55 E-value: 3.68e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 4 NAVLSMKNVSF---ERDKIILKNINWSLHSGENWVLMGLNGAGKTTLLSLIYGNHWATTGSIEVLG--------ETFGKT 72
Cdd:TIGR01842 314 EGHLSVENVTIvppGGKKPTLRGISFSLQAGEALAIIGPSGSGKSTLARLIVGIWPPTSGSVRLDGadlkqwdrETFGKH 393
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 73 nVLALKKRIGLISTAVQ---SQFPEHHLAQYIVLSGKFGtiGIHndfekndlnEAIGLLKKlGGDELVNKPYRVLSQGQR 149
Cdd:TIGR01842 394 -IGYLPQDVELFPGTVAeniARFGENADPEKIIEAAKLA--GVH---------ELILRLPD-GYDTVIGPGGATLSGGQR 460
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 150 QLVLIARALLGKPELLILDEPCNGLDLFSRELLLEQINKLAQlpNHPTLLFVSHYTeEILPIFKNIMLLKQGEIFAQGTR 229
Cdd:TIGR01842 461 QRIALARALYGDPKLVVLDEPNSNLDEEGEQALANAIKALKA--RGITVVVITHRP-SLLGCVDKILVLQDGRIARFGER 537
|
....*.
gi 915796356 230 DKILTE 235
Cdd:TIGR01842 538 DEVLAK 543
|
|
| CydD |
TIGR02857 |
thiol reductant ABC exporter, CydD subunit; The gene pair cydCD encodes an ABC-family ... |
7-203 |
3.80e-18 |
|
thiol reductant ABC exporter, CydD subunit; The gene pair cydCD encodes an ABC-family transporter in which each gene contains an N-terminal membrane-spanning domain (pfam00664) and a C-terminal ATP-binding domain (pfam00005). In E. coli these genes were discovered as mutants which caused the terminal heme-copper oxidase complex cytochrome bd to fail to assemble. Recent work has shown that the transporter is involved in export of redox-active thiol compounds such as cysteine and glutathione. The linkage to assembly of the cytochrome bd complex is further supported by the conserved operon structure found outside the gammaproteobacteria (cydABCD) containing both the transporter and oxidase genes components. The genes used as the seed members for this model are all either found in the gammproteobacterial context or the CydABCD context. All members of this family scoring above trusted at the time of its creation were from genomes which encode a cytochrome bd complex. Unfortunately, the gene symbol nomenclature adopted based on this operon in B. subtilis assigns cydC to the third gene in the operon where this gene is actually homologous to the E. coli cydD gene. We have chosen to name all homologs in this family in accordance with the precedence of publication of the E. coli name, CydD
Pssm-ID: 274323 [Multi-domain] Cd Length: 529 Bit Score: 83.49 E-value: 3.80e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 7 LSMKNVSF---ERDKIiLKNINWSLHSGENWVLMGLNGAGKTTLLSLIYGNHWATTGSIEVLGETFGKTNVLALKKRIGL 83
Cdd:TIGR02857 322 LEFSGVSVaypGRRPA-LRPVSFTVPPGERVALVGPSGAGKSTLLNLLLGFVDPTEGSIAVNGVPLADADADSWRDQIAW 400
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 84 ISTavQSQFPEHHLAQYIVLSGKFGT-IGIHNDFEKNDLNEAIGLLKkLGGDELVNKPYRVLSQGQRQLVLIARALLGKP 162
Cdd:TIGR02857 401 VPQ--HPFLFAGTIAENIRLARPDASdAEIREALERAGLDEFVAALP-QGLDTPIGEGGAGLSGGQAQRLALARAFLRDA 477
|
170 180 190 200
....*....|....*....|....*....|....*....|.
gi 915796356 163 ELLILDEPCNGLDLFSRELLLEQINKLAQlpNHpTLLFVSH 203
Cdd:TIGR02857 478 PLLLLDEPTAHLDAETEAEVLEALRALAQ--GR-TVLLVTH 515
|
|
| cbiO |
PRK13652 |
cobalt transporter ATP-binding subunit; Provisional |
13-238 |
5.21e-18 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 172200 [Multi-domain] Cd Length: 277 Bit Score: 81.00 E-value: 5.21e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 13 SFERDKIILKNINWSLHSGENWVLMGLNGAGKTTLLSLIYGNHWATTGSIEVLGETFGKTNVLALKKRIGLISTAVQSQF 92
Cdd:PRK13652 12 SYSGSKEALNNINFIAPRNSRIAVIGPNGAGKSTLFRHFNGILKPTSGSVLIRGEPITKENIREVRKFVGLVFQNPDDQI 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 93 PEHHLAQYIVlsgkFGTIGIHNDFE--KNDLNEAiglLKKLGGDELVNKPYRVLSQGQRQLVLIARALLGKPELLILDEP 170
Cdd:PRK13652 92 FSPTVEQDIA----FGPINLGLDEEtvAHRVSSA---LHMLGLEELRDRVPHHLSGGEKKRVAIAGVIAMEPQVLVLDEP 164
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 915796356 171 CNGLDLFSRELLLEQINKLAQLPNHpTLLFVSHYTEEILPIFKNIMLLKQGEIFAQGTRDKILTENVL 238
Cdd:PRK13652 165 TAGLDPQGVKELIDFLNDLPETYGM-TVIFSTHQLDLVPEMADYIYVMDKGRIVAYGTVEEIFLQPDL 231
|
|
| PRK10253 |
PRK10253 |
iron-enterobactin ABC transporter ATP-binding protein; |
18-242 |
5.24e-18 |
|
iron-enterobactin ABC transporter ATP-binding protein;
Pssm-ID: 182336 [Multi-domain] Cd Length: 265 Bit Score: 81.19 E-value: 5.24e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 18 KIILKNINWSLHSGENWVLMGLNGAGKTTLLSLIYGNHWATTGSIEVLGETFGKTNVLALKKRIGLIstAVQSQFPEHHL 97
Cdd:PRK10253 20 YTVAENLTVEIPDGHFTAIIGPNGCGKSTLLRTLSRLMTPAHGHVWLDGEHIQHYASKEVARRIGLL--AQNATTPGDIT 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 98 AQYIVLSGKFGTIGIHNDFEKNDLNEAIGLLKKLGGDELVNKPYRVLSQGQRQLVLIARALLGKPELLILDEPCNGLDLF 177
Cdd:PRK10253 98 VQELVARGRYPHQPLFTRWRKEDEEAVTKAMQATGITHLADQSVDTLSGGQRQRAWIAMVLAQETAIMLLDEPTTWLDIS 177
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 915796356 178 SRELLLEQINKLAQLPNHpTLLFVSHYTEEILPIFKNIMLLKQGEIFAQGTRDKILTENVLSKFY 242
Cdd:PRK10253 178 HQIDLLELLSELNREKGY-TLAAVLHDLNQACRYASHLIALREGKIVAQGAPKEIVTAELIERIY 241
|
|
| ABCG_White |
cd03234 |
White pigment protein homolog of ABCG transporter subfamily; The White subfamily represents ... |
6-227 |
5.99e-18 |
|
White pigment protein homolog of ABCG transporter subfamily; The White subfamily represents ABC transporters homologous to the Drosophila white gene, which acts as a dimeric importer for eye pigment precursors. The eye pigmentation of Drosophila is developed from the synthesis and deposition in the cells of red pigments, which are synthesized from guanine, and brown pigments, which are synthesized from tryptophan. The pigment precursors are encoded by the white, brown, and scarlet genes, respectively. Evidence from genetic and biochemical studies suggest that the White and Brown proteins function as heterodimers to import guanine, while the White and Scarlet proteins function to import tryptophan. However, a recent study also suggests that White may be involved in the transport of a metabolite, such as 3-hydroxykynurenine, across intracellular membranes. Mammalian ABC transporters belonging to the White subfamily (ABCG1, ABCG5, and ABCG8) have been shown to be involved in the regulation of lipid-trafficking mechanisms in macrophages, hepatocytes, and intestinal mucosa cells. ABCG1 (ABC8), the human homolog of the Drosophila white gene is induced in monocyte-derived macrophages during cholesterol influx mediated by acetylated low-density lipoprotein. It is possible that human ABCG1 forms heterodimers with several heterologous partners.
Pssm-ID: 213201 [Multi-domain] Cd Length: 226 Bit Score: 80.01 E-value: 5.99e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 6 VLSMKNVSFER-----DKIILKNINWSLHSGENWVLMGLNGAGKTTLLSLIYG---NHWATTGSIEVLGEtfgktnvlAL 77
Cdd:cd03234 3 VLPWWDVGLKAknwnkYARILNDVSLHVESGQVMAILGSSGSGKTTLLDAISGrveGGGTTSGQILFNGQ--------PR 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 78 KKRIGLISTAVQSQF----PEHHLAQYIVLSGKFGTIGIHNDFEKNDLnEAIGLLKKLGGDELVNKPYRVLSQGQRQLVL 153
Cdd:cd03234 75 KPDQFQKCVAYVRQDdillPGLTVRETLTYTAILRLPRKSSDAIRKKR-VEDVLLRDLALTRIGGNLVKGISGGERRRVS 153
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 915796356 154 IARALLGKPELLILDEPCNGLDLFSRELLLEQINKLAQlPNHPTLLFVSHYTEEILPIFKNIMLLKQGEIFAQG 227
Cdd:cd03234 154 IAVQLLWDPKVLILDEPTSGLDSFTALNLVSTLSQLAR-RNRIVILTIHQPRSDLFRLFDRILLLSSGEIVYSG 226
|
|
| COG4586 |
COG4586 |
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ... |
14-234 |
6.18e-18 |
|
ABC-type uncharacterized transport system, ATPase component [General function prediction only];
Pssm-ID: 443643 [Multi-domain] Cd Length: 323 Bit Score: 81.67 E-value: 6.18e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 14 FERDKII---LKNINWSLHSGENWVLMGLNGAGKTTLLSLIYGNHWATTGSIEVLGET-FGKTNvlALKKRIGListaV- 88
Cdd:COG4586 28 FRREYREveaVDDISFTIEPGEIVGFIGPNGAGKSTTIKMLTGILVPTSGEVRVLGYVpFKRRK--EFARRIGV----Vf 101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 89 -Q-SQfpehhLAQYIVLSGKFGTIG-IHN----DFEKNdLNEAIGLLKkLGgdELVNKPYRVLSQGQRQLVLIARALLGK 161
Cdd:COG4586 102 gQrSQ-----LWWDLPAIDSFRLLKaIYRipdaEYKKR-LDELVELLD-LG--ELLDTPVRQLSLGQRMRCELAAALLHR 172
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 915796356 162 PELLILDEPCNGLDLFS----RELLLEqINKlaqlPNHPTLLFVSHYTEEILPIFKNIMLLKQGEIFAQGTRDKILT 234
Cdd:COG4586 173 PKILFLDEPTIGLDVVSkeaiREFLKE-YNR----ERGTTILLTSHDMDDIEALCDRVIVIDHGRIIYDGSLEELKE 244
|
|
| PRK13537 |
PRK13537 |
nodulation factor ABC transporter ATP-binding protein NodI; |
5-227 |
9.70e-18 |
|
nodulation factor ABC transporter ATP-binding protein NodI;
Pssm-ID: 237420 [Multi-domain] Cd Length: 306 Bit Score: 81.00 E-value: 9.70e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 5 AVLSMKNVSFER-DKIILKNINWSLHSGENWVLMGLNGAGKTTLLSLIYGNHWATTGSIEVLGETFGKTNVLAlKKRIGL 83
Cdd:PRK13537 6 APIDFRNVEKRYgDKLVVDGLSFHVQRGECFGLLGPNGAGKTTTLRMLLGLTHPDAGSISLCGEPVPSRARHA-RQRVGV 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 84 IStavqsQF----PEHHLAQYIVLSGK-FGtigihndFEKNDLNEAI-GLLKKLGGDELVNKPYRVLSQGQRQLVLIARA 157
Cdd:PRK13537 85 VP-----QFdnldPDFTVRENLLVFGRyFG-------LSAAAARALVpPLLEFAKLENKADAKVGELSGGMKRRLTLARA 152
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 158 LLGKPELLILDEPCNGLDLFSRELLLEQINKLaqLPNHPTLLFVSHYTEEILPIFKNIMLLKQGEIFAQG 227
Cdd:PRK13537 153 LVNDPDVLVLDEPTTGLDPQARHLMWERLRSL--LARGKTILLTTHFMEEAERLCDRLCVIEEGRKIAEG 220
|
|
| ABCC_cytochrome_bd |
cd03247 |
ATP-binding cassette domain of CydCD, subfamily C; The CYD subfamily implicated in cytochrome ... |
7-227 |
1.25e-17 |
|
ATP-binding cassette domain of CydCD, subfamily C; The CYD subfamily implicated in cytochrome bd biogenesis. The CydC and CydD proteins are important for the formation of cytochrome bd terminal oxidase of E. coli and it has been proposed that they were necessary for biosynthesis of the cytochrome bd quinol oxidase and for periplasmic c-type cytochromes. CydCD were proposed to determine a heterooligomeric complex important for heme export into the periplasm or to be involved in the maintenance of the proper redox state of the periplasmic space. In Bacillus subtilis, the absence of CydCD does not affect the presence of halo-cytochrome c in the membrane and this observation suggests that CydCD proteins are not involved in the export of heme in this organism.
Pssm-ID: 213214 [Multi-domain] Cd Length: 178 Bit Score: 78.12 E-value: 1.25e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 7 LSMKNVSF---ERDKIILKNINWSLHSGENWVLMGLNGAGKTTLLSLIYGNHWATTGSIevlgeTFGKTNVLALKKRIG- 82
Cdd:cd03247 1 LSINNVSFsypEQEQQVLKNLSLELKQGEKIALLGRSGSGKSTLLQLLTGDLKPQQGEI-----TLDGVPVSDLEKALSs 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 83 LIStaVQSQFPehHLaqyivlsgkFGTIgihndfekndlneaigLLKKLGgdelvnkpyRVLSQGQRQLVLIARALLGKP 162
Cdd:cd03247 76 LIS--VLNQRP--YL---------FDTT----------------LRNNLG---------RRFSGGERQRLALARILLQDA 117
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 915796356 163 ELLILDEPCNGLDLFSRELLLEQINKLAQlpnHPTLLFVSHYTEEIlPIFKNIMLLKQGEIFAQG 227
Cdd:cd03247 118 PIVLLDEPTVGLDPITERQLLSLIFEVLK---DKTLIWITHHLTGI-EHMDKILFLENGKIIMQG 178
|
|
| ABCC_MRP_domain2 |
cd03244 |
ATP-binding cassette domain 2 of multidrug resistance-associated protein; The ABC subfamily C ... |
20-228 |
1.40e-17 |
|
ATP-binding cassette domain 2 of multidrug resistance-associated protein; The ABC subfamily C is also known as MRP (multidrug resistance-associated protein). Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resistance lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions, such as glutathione, glucuronate, and sulfate.
Pssm-ID: 213211 [Multi-domain] Cd Length: 221 Bit Score: 78.69 E-value: 1.40e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 20 ILKNINWSLHSGENWVLMGLNGAGKTTLLSLIYGNHWATTGSIEVLGETFGKTNVLALKKRIGLIStavqsQFPehhlaq 99
Cdd:cd03244 19 VLKNISFSIKPGEKVGIVGRTGSGKSSLLLALFRLVELSSGSILIDGVDISKIGLHDLRSRISIIP-----QDP------ 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 100 yIVLSGkfgTI-------GIHNDFEkndLNEAiglLKKLGGDELVNKP-----YRV------LSQGQRQLVLIARALLGK 161
Cdd:cd03244 88 -VLFSG---TIrsnldpfGEYSDEE---LWQA---LERVGLKEFVESLpggldTVVeeggenLSVGQRQLLCLARALLRK 157
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 915796356 162 PELLILDEPCNGLDLFSRELLLEQI-NKLAqlpnHPTLLFVSHYTEEILPiFKNIMLLKQGEIFAQGT 228
Cdd:cd03244 158 SKILVLDEATASVDPETDALIQKTIrEAFK----DCTVLTIAHRLDTIID-SDRILVLDKGRVVEFDS 220
|
|
| PotA |
COG3842 |
ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component [Amino acid transport ... |
3-228 |
2.33e-17 |
|
ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 443052 [Multi-domain] Cd Length: 353 Bit Score: 80.14 E-value: 2.33e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 3 NNAVLSMKNVSFER-DKIILKNINWSLHSGENWVLMGLNGAGKTTLLSLIYGNHWATTGSIEVLGETFgkTNVLALKKRI 81
Cdd:COG3842 2 AMPALELENVSKRYgDVTALDDVSLSIEPGEFVALLGPSGCGKTTLLRMIAGFETPDSGRILLDGRDV--TGLPPEKRNV 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 82 GLIStavQSQ--FPehHLaqyivlsgkfgTIgihndFEkndlNEAIGL-LKKLGGDE----------LVN-------KPY 141
Cdd:COG3842 80 GMVF---QDYalFP--HL-----------TV-----AE----NVAFGLrMRGVPKAEirarvaelleLVGlegladrYPH 134
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 142 RvLSQGQRQLVLIARALLGKPELLILDEPCNGLDLFSRELLLEQINKL-AQLpnHPTLLFVSHYTEEILPIFKNIMLLKQ 220
Cdd:COG3842 135 Q-LSGGQQQRVALARALAPEPRVLLLDEPLSALDAKLREEMREELRRLqREL--GITFIYVTHDQEEALALADRIAVMND 211
|
....*...
gi 915796356 221 GEIFAQGT 228
Cdd:COG3842 212 GRIEQVGT 219
|
|
| TauB |
COG4525 |
ABC-type taurine transport system, ATPase component [Inorganic ion transport and metabolism]; |
5-209 |
2.64e-17 |
|
ABC-type taurine transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 443596 [Multi-domain] Cd Length: 262 Bit Score: 78.75 E-value: 2.64e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 5 AVLSMKNVS-----FERDKIILKNINWSLHSGENWVLMGLNGAGKTTLLSLIYGNHWATTGSIEVLGEtfgktnvlalkk 79
Cdd:COG4525 2 SMLTVRHVSvrypgGGQPQPALQDVSLTIESGEFVVALGASGCGKTTLLNLIAGFLAPSSGEITLDGV------------ 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 80 riglistAVQSQ-------FPEHHL------AQYIVLSGKFGTIGIHndfEKNDLNEAigLLKKLGGDELVNKPYRVLSQ 146
Cdd:COG4525 70 -------PVTGPgadrgvvFQKDALlpwlnvLDNVAFGLRLRGVPKA---ERRARAEE--LLALVGLADFARRRIWQLSG 137
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 915796356 147 GQRQLVLIARALLGKPELLILDEPCNGLDLFSRELLLEQINKLAQLpNHPTLLFVSHYTEEIL 209
Cdd:COG4525 138 GMRQRVGIARALAADPRFLLMDEPFGALDALTREQMQELLLDVWQR-TGKGVFLITHSVEEAL 199
|
|
| ABC_CysA_sulfate_importer |
cd03296 |
ATP-binding cassette domain of the sulfate transporter; Part of the ABC transporter complex ... |
21-232 |
2.79e-17 |
|
ATP-binding cassette domain of the sulfate transporter; Part of the ABC transporter complex cysAWTP involved in sulfate import. Responsible for energy coupling to the transport system. The complex is composed of two ATP-binding proteins (cysA), two transmembrane proteins (cysT and cysW), and a solute-binding protein (cysP). ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213263 [Multi-domain] Cd Length: 239 Bit Score: 78.54 E-value: 2.79e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 21 LKNINWSLHSGENWVLMGLNGAGKTTLLSLIYGNHWATTGSIEVLGETFGKTNVLalKKRIGLIstavqsqFPEHHLAQY 100
Cdd:cd03296 18 LDDVSLDIPSGELVALLGPSGSGKTTLLRLIAGLERPDSGTILFGGEDATDVPVQ--ERNVGFV-------FQHYALFRH 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 101 IVLSGK--FGtIGIHNDFEKNDLNE----AIGLLKKLGGDELVNKPYRVLSQGQRQLVLIARALLGKPELLILDEPCNGL 174
Cdd:cd03296 89 MTVFDNvaFG-LRVKPRSERPPEAEirakVHELLKLVQLDWLADRYPAQLSGGQRQRVALARALAVEPKVLLLDEPFGAL 167
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 915796356 175 DLFSRELLLEQINKLAQLPNHpTLLFVSHYTEEILPIFKNIMLLKQGEIFAQGTRDKI 232
Cdd:cd03296 168 DAKVRKELRRWLRRLHDELHV-TTVFVTHDQEEALEVADRVVVMNKGRIEQVGTPDEV 224
|
|
| drrA |
TIGR01188 |
daunorubicin resistance ABC transporter ATP-binding subunit; This model describes daunorubicin ... |
21-228 |
3.13e-17 |
|
daunorubicin resistance ABC transporter ATP-binding subunit; This model describes daunorubicin resistance ABC transporter, ATP binding subunit in bacteria and archaea. This model is restricted in its scope to preferentially recognize the ATP binding subunit associated with effux of the drug, daunorubicin. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporter is the obligatory coupling of ATP hydrolysis to substrate translocation. The minimal configuration of bacterial ABC transport system: an ATPase or ATP binding subunit; An integral membrane protein; a hydrophilic polypetpide, which likely functions as substrate binding protein. In eukaryotes proteins of similar function include p-gyco proteins, multidrug resistance protein etc. [Transport and binding proteins, Other]
Pssm-ID: 130256 [Multi-domain] Cd Length: 302 Bit Score: 79.36 E-value: 3.13e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 21 LKNINWSLHSGENWVLMGLNGAGKTTLLSLIYGNHWATTGSIEVLGETFGKtNVLALKKRIGLIStavQSQFPEHHLA-- 98
Cdd:TIGR01188 9 VDGVNFKVREGEVFGFLGPNGAGKTTTIRMLTTLLRPTSGTARVAGYDVVR-EPRKVRRSIGIVP---QYASVDEDLTgr 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 99 QYIVLSGKFgtIGIHNDFEKNDLNEaigLLKKLGGDELVNKPYRVLSQGQRQLVLIARALLGKPELLILDEPCNGLDLFS 178
Cdd:TIGR01188 85 ENLEMMGRL--YGLPKDEAEERAEE---LLELFELGEAADRPVGTYSGGMRRRLDIAASLIHQPDVLFLDEPTTGLDPRT 159
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 915796356 179 RELLLEQINKLAQLPNhpTLLFVSHYTEEILPIFKNIMLLKQGEIFAQGT 228
Cdd:TIGR01188 160 RRAIWDYIRALKEEGV--TILLTTHYMEEADKLCDRIAIIDHGRIIAEGT 207
|
|
| ntrCD |
TIGR01184 |
nitrate transport ATP-binding subunits C and D; This model describes the ATP binding subunits ... |
21-221 |
4.04e-17 |
|
nitrate transport ATP-binding subunits C and D; This model describes the ATP binding subunits of nitrate transport in bacteria and archaea. This protein belongs to the ATP-binding cassette (ABC) superfamily. It is thought that the two subunits encoded by ntrC and ntrD form the binding surface for interaction with ATP. This model is restricted in identifying ATP binding subunit associated with the nitrate transport. Nitrate assimilation is aided by other proteins derived from the operon which among others include products of ntrA - a regulatory protein; ntrB - a hydropbobic transmembrane permease and narB - a reductase. [Transport and binding proteins, Anions, Transport and binding proteins, Other]
Pssm-ID: 130252 [Multi-domain] Cd Length: 230 Bit Score: 77.89 E-value: 4.04e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 21 LKNINWSLHSGENWVLMGLNGAGKTTLLSLIYGNHWATTGSIEVLGE-----------TFGKTNVL---ALKKRIGLIST 86
Cdd:TIGR01184 1 LKGVNLTIQQGEFISLIGHSGCGKSTLLNLISGLAQPTSGGVILEGKqitepgpdrmvVFQNYSLLpwlTVRENIALAVD 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 87 AVQSQFPEHHLAQYIvlsgkfgtigihndfekndlNEAIGLLkklGGDELVNKPYRVLSQGQRQLVLIARALLGKPELLI 166
Cdd:TIGR01184 81 RVLPDLSKSERRAIV--------------------EEHIALV---GLTEAADKRPGQLSGGMKQRVAIARALSIRPKVLL 137
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 915796356 167 LDEPCNGLDLFSRELLLEQINKLAQlPNHPTLLFVSHYTEEILPIFKNIMLLKQG 221
Cdd:TIGR01184 138 LDEPFGALDALTRGNLQEELMQIWE-EHRVTVLMVTHDVDEALLLSDRVVMLTNG 191
|
|
| PRK11174 |
PRK11174 |
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed |
17-236 |
4.64e-17 |
|
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed
Pssm-ID: 236870 [Multi-domain] Cd Length: 588 Bit Score: 80.27 E-value: 4.64e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 17 DKIILKNINWSLHSGENWVLMGLNGAGKTTLLSLIYGNhWATTGSIEVLGETFGKTNVLALKKRIGLISTavQSQFPEHH 96
Cdd:PRK11174 362 GKTLAGPLNFTLPAGQRIALVGPSGAGKTSLLNALLGF-LPYQGSLKINGIELRELDPESWRKHLSWVGQ--NPQLPHGT 438
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 97 LAQYIVLSGKFGTIG-IHNDFEKNDLNEAIGLLKkLGGDELVNKPYRVLSQGQRQLVLIARALLGKPELLILDEPCNGLD 175
Cdd:PRK11174 439 LRDNVLLGNPDASDEqLQQALENAWVSEFLPLLP-QGLDTPIGDQAAGLSVGQAQRLALARALLQPCQLLLLDEPTASLD 517
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 915796356 176 LFSRELLLEQINKLAQlpnHPTLLFVSHYTEEiLPIFKNIMLLKQGEIFAQGTRDKILTEN 236
Cdd:PRK11174 518 AHSEQLVMQALNAASR---RQTTLMVTHQLED-LAQWDQIWVMQDGQIVQQGDYAELSQAG 574
|
|
| potA |
TIGR01187 |
spermidine/putrescine ABC transporter ATP-binding subunit; This model describes spermidine ... |
36-253 |
5.06e-17 |
|
spermidine/putrescine ABC transporter ATP-binding subunit; This model describes spermidine/putrescine ABC transporter, ATP binding subunit in bacteria and its equivalents in archaea. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporter is the obligatory coupling of ATP hydrolysis to substrate translocation. The minimal configuration of bacterial ABC transport system: an ATPase or ATP binding subunit; An integral membrane protein; a hydrophilic polypetpide, which likely functions as substrate binding protein. Polyamines like spermidine and putrescine play vital role in cell proliferation, differentiation, and ion homeostasis. The concentration of polyamines within the cell are regulated by biosynthesis, degradation and transport (uptake and efflux included). [Transport and binding proteins, Amino acids, peptides and amines]
Pssm-ID: 162242 [Multi-domain] Cd Length: 325 Bit Score: 79.07 E-value: 5.06e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 36 LMGLNGAGKTTLLSLIYGNHWATTGSIEVLGETFgkTNVLALKKRIGlisTAVQSQ--FPEHHLAQYIVLSGKFGtiGIH 113
Cdd:TIGR01187 1 LLGPSGCGKTTLLRLLAGFEQPDSGSIMLDGEDV--TNVPPHLRHIN---MVFQSYalFPHMTVEENVAFGLKMR--KVP 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 114 NDFEKNDLNEAIGLLKKlgGDELVNKPYRvLSQGQRQLVLIARALLGKPELLILDEPCNGLDLFSRELL-LEQINKLAQL 192
Cdd:TIGR01187 74 RAEIKPRVLEALRLVQL--EEFADRKPHQ-LSGGQQQRVALARALVFKPKILLLDEPLSALDKKLRDQMqLELKTIQEQL 150
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 915796356 193 pnHPTLLFVSHYTEEILPIFKNIMLLKQGEIFAQGTRDKILTE--NVLSKFYPKPIKIFPVTN 253
Cdd:TIGR01187 151 --GITFVFVTHDQEEAMTMSDRIAIMRKGKIAQIGTPEEIYEEpaNLFVARFIGEINVFEATV 211
|
|
| PRK13633 |
PRK13633 |
energy-coupling factor transporter ATPase; |
3-235 |
6.76e-17 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 237453 [Multi-domain] Cd Length: 280 Bit Score: 78.21 E-value: 6.76e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 3 NNAVLSMKNVSFE-------RDKIILKNINWSLHSGENWVLMGLNGAGKTTLLSLIYGNHWATTGSIEVLG-ETFGKTNV 74
Cdd:PRK13633 1 MNEMIKCKNVSYKyesneesTEKLALDDVNLEVKKGEFLVILGRNGSGKSTIAKHMNALLIPSEGKVYVDGlDTSDEENL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 75 LALKKRIGLIStavqsQFPEHHLAQYIVLSG-KFG--TIGIHNDFEKNDLNEAiglLKKLGGDELVNKPYRVLSQGQRQL 151
Cdd:PRK13633 81 WDIRNKAGMVF-----QNPDNQIVATIVEEDvAFGpeNLGIPPEEIRERVDES---LKKVGMYEYRRHAPHLLSGGQKQR 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 152 VLIARALLGKPELLILDEPCNGLDLFSRELLLEQINKLAQlPNHPTLLFVSHYTEEILPIFKnIMLLKQGEIFAQGTRDK 231
Cdd:PRK13633 153 VAIAGILAMRPECIIFDEPTAMLDPSGRREVVNTIKELNK-KYGITIILITHYMEEAVEADR-IIVMDSGKVVMEGTPKE 230
|
....
gi 915796356 232 ILTE 235
Cdd:PRK13633 231 IFKE 234
|
|
| PRK03695 |
PRK03695 |
vitamin B12-transporter ATPase; Provisional |
31-252 |
7.27e-17 |
|
vitamin B12-transporter ATPase; Provisional
Pssm-ID: 235150 [Multi-domain] Cd Length: 248 Bit Score: 77.67 E-value: 7.27e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 31 GENWVLMGLNGAGKTTLLSLIYGnhwATTGSIEVlgeTFGKTNVLA-----LKKRIGLIStavQSQFPEHHLA--QYIVL 103
Cdd:PRK03695 22 GEILHLVGPNGAGKSTLLARMAG---LLPGSGSI---QFAGQPLEAwsaaeLARHRAYLS---QQQTPPFAMPvfQYLTL 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 104 SGKFGTIGIHNDFEKNDLNEAIGLLKKLGgdelvnKPYRVLSQGQRQLVLIARALL-----GKPE--LLILDEPCNGLDL 176
Cdd:PRK03695 93 HQPDKTRTEAVASALNEVAEALGLDDKLG------RSVNQLSGGEWQRVRLAAVVLqvwpdINPAgqLLLLDEPMNSLDV 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 177 FSRELLLEQINKLAQLP----------NHpTLlfvsHYTEEILpifknimLLKQGEIFAQGTRDKILTENVLSKFYPKPI 246
Cdd:PRK03695 167 AQQAALDRLLSELCQQGiavvmsshdlNH-TL----RHADRVW-------LLKQGKLLASGRRDEVLTPENLAQVFGVNF 234
|
....*.
gi 915796356 247 KIFPVT 252
Cdd:PRK03695 235 RRLDVE 240
|
|
| cbiO |
PRK13639 |
cobalt transporter ATP-binding subunit; Provisional |
13-235 |
7.72e-17 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 184199 [Multi-domain] Cd Length: 275 Bit Score: 77.81 E-value: 7.72e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 13 SFERDKIILKNINWSLHSGENWVLMGLNGAGKTTLLSLIYGNHWATTGSIEVLGET--FGKTNVLALKKRIGLIStavqs 90
Cdd:PRK13639 10 SYPDGTEALKGINFKAEKGEMVALLGPNGAGKSTLFLHFNGILKPTSGEVLIKGEPikYDKKSLLEVRKTVGIVF----- 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 91 QFPEHHLAQYIVLSG-KFG--TIGIHNDFEKNDLNEAiglLKKLGGDELVNKPYRVLSQGQRQLVLIARALLGKPELLIL 167
Cdd:PRK13639 85 QNPDDQLFAPTVEEDvAFGplNLGLSKEEVEKRVKEA---LKAVGMEGFENKPPHHLSGGQKKRVAIAGILAMKPEIIVL 161
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 168 DEPCNGLDlfsrELLLEQINK-LAQLPNHPTLLFVSHYTEEILPIFKN-IMLLKQGEIFAQGTRDKILTE 235
Cdd:PRK13639 162 DEPTSGLD----PMGASQIMKlLYDLNKEGITIIISTHDVDLVPVYADkVYVMSDGKIIKEGTPKEVFSD 227
|
|
| PRK09700 |
PRK09700 |
D-allose ABC transporter ATP-binding protein AlsA; |
6-235 |
1.01e-16 |
|
D-allose ABC transporter ATP-binding protein AlsA;
Pssm-ID: 182036 [Multi-domain] Cd Length: 510 Bit Score: 79.06 E-value: 1.01e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 6 VLSMKNVSfERDKIILKNINWSLHSGENWVLMGLNGAGKTTLLSLIYGNHWATTGSIEVLGETFG-KTNVLALKKRIGLI 84
Cdd:PRK09700 265 VFEVRNVT-SRDRKKVRDISFSVCRGEILGFAGLVGSGRTELMNCLFGVDKRAGGEIRLNGKDISpRSPLDAVKKGMAYI 343
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 85 STAVQSQ--FPEHHLAQYIVLS-----GKF-GTIGIHNDFEKNDLNEAIGLLKKLGGDElVNKPYRVLSQGQRQLVLIAR 156
Cdd:PRK09700 344 TESRRDNgfFPNFSIAQNMAISrslkdGGYkGAMGLFHEVDEQRTAENQRELLALKCHS-VNQNITELSGGNQQKVLISK 422
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 915796356 157 ALLGKPELLILDEPCNGLDLFSRELLLEQINKLAQlpNHPTLLFVSHYTEEILPIFKNIMLLKQGEIFAQGTRDKILTE 235
Cdd:PRK09700 423 WLCCCPEVIIFDEPTRGIDVGAKAEIYKVMRQLAD--DGKVILMVSSELPEIITVCDRIAVFCEGRLTQILTNRDDMSE 499
|
|
| znuC |
PRK09544 |
high-affinity zinc transporter ATPase; Reviewed |
1-203 |
1.07e-16 |
|
high-affinity zinc transporter ATPase; Reviewed
Pssm-ID: 181939 [Multi-domain] Cd Length: 251 Bit Score: 77.08 E-value: 1.07e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 1 MTNNAVLSMKNVSFERDKIiLKNINWSLHSGENWVLMGLNGAGKTTLLSLIYGNHWATTGSIEVLGetfgktnvlalKKR 80
Cdd:PRK09544 1 MTSLVSLENVSVSFGQRRV-LSDVSLELKPGKILTLLGPNGAGKSTLVRVVLGLVAPDEGVIKRNG-----------KLR 68
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 81 IGLISTAVqsqfpehHLAQYIVLS-GKFgtIGIHNDFEKNDLNEAiglLKKLGGDELVNKPYRVLSQGQRQLVLIARALL 159
Cdd:PRK09544 69 IGYVPQKL-------YLDTTLPLTvNRF--LRLRPGTKKEDILPA---LKRVQAGHLIDAPMQKLSGGETQRVLLARALL 136
|
170 180 190 200
....*....|....*....|....*....|....*....|....
gi 915796356 160 GKPELLILDEPCNGLDLFSRELLLEQINKLAQLPNHPTLLfVSH 203
Cdd:PRK09544 137 NRPQLLVLDEPTQGVDVNGQVALYDLIDQLRRELDCAVLM-VSH 179
|
|
| PRK15134 |
PRK15134 |
microcin C ABC transporter ATP-binding protein YejF; Provisional |
18-227 |
1.14e-16 |
|
microcin C ABC transporter ATP-binding protein YejF; Provisional
Pssm-ID: 237917 [Multi-domain] Cd Length: 529 Bit Score: 78.98 E-value: 1.14e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 18 KIILKNINWSLHSGENWVLMGLNGAGKTT----LLSLIygnhwATTGSIEVLG---ETFGKTNVLALKKRIglistAVQS 90
Cdd:PRK15134 299 NVVVKNISFTLRPGETLGLVGESGSGKSTtglaLLRLI-----NSQGEIWFDGqplHNLNRRQLLPVRHRI-----QVVF 368
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 91 QFPEHHL-----AQYIVLSGkfgtIGIHndfeKNDLNEA------IGLLKKLGGDELVNKPYRV-LSQGQRQLVLIARAL 158
Cdd:PRK15134 369 QDPNSSLnprlnVLQIIEEG----LRVH----QPTLSAAqreqqvIAVMEEVGLDPETRHRYPAeFSGGQRQRIAIARAL 440
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 915796356 159 LGKPELLILDEPCNGLDLFSRELLLEQINKLAQlPNHPTLLFVSHYTEEILPIFKNIMLLKQGEIFAQG 227
Cdd:PRK15134 441 ILKPSLIILDEPTSSLDKTVQAQILALLKSLQQ-KHQLAYLFISHDLHVVRALCHQVIVLRQGEVVEQG 508
|
|
| cbiO |
PRK13646 |
energy-coupling factor transporter ATPase; |
21-228 |
1.64e-16 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184205 [Multi-domain] Cd Length: 286 Bit Score: 77.13 E-value: 1.64e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 21 LKNINWSLHSGENWVLMGLNGAGKTTLLSLIYGNHWATTGSIEVLGETF-GKTN---VLALKKRIGLISTAVQSQFPEHH 96
Cdd:PRK13646 23 IHDVNTEFEQGKYYAIVGQTGSGKSTLIQNINALLKPTTGTVTVDDITItHKTKdkyIRPVRKRIGMVFQFPESQLFEDT 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 97 LAQYIVlsgkFGTIGIHNDFEKNDlNEAIGLLKKLG--GDELVNKPYRvLSQGQRQLVLIARALLGKPELLILDEPCNGL 174
Cdd:PRK13646 103 VEREII----FGPKNFKMNLDEVK-NYAHRLLMDLGfsRDVMSQSPFQ-MSGGQMRKIAIVSILAMNPDIIVLDEPTAGL 176
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 915796356 175 DLFSRELLLEQINKLaQLPNHPTLLFVSHYTEEILPIFKNIMLLKQGEIFAQGT 228
Cdd:PRK13646 177 DPQSKRQVMRLLKSL-QTDENKTIILVSHDMNEVARYADEVIVMKEGSIVSQTS 229
|
|
| thiQ |
PRK10771 |
thiamine ABC transporter ATP-binding protein ThiQ; |
19-237 |
2.18e-16 |
|
thiamine ABC transporter ATP-binding protein ThiQ;
Pssm-ID: 182716 [Multi-domain] Cd Length: 232 Bit Score: 75.77 E-value: 2.18e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 19 IILKNINW---------SLH--SGENWVLMGLNGAGKTTLLSLIYGNHWATTGSIEVLGETFGKTnvlALKKRIglISTA 87
Cdd:PRK10771 2 LKLTDITWlyhhlpmrfDLTveRGERVAILGPSGAGKSTLLNLIAGFLTPASGSLTLNGQDHTTT---PPSRRP--VSML 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 88 VQSQ--FPEHHLAQYIVLsgkfgtiGIH-----NDFEKNDLNEaigLLKKLGGDELVNKPYRVLSQGQRQLVLIARALLG 160
Cdd:PRK10771 77 FQENnlFSHLTVAQNIGL-------GLNpglklNAAQREKLHA---IARQMGIEDLLARLPGQLSGGQRQRVALARCLVR 146
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 161 KPELLILDEPCNGLDLFSR-EL--LLEQINKLAQLpnhpTLLFVSHYTEEILPIFKNIMLLKQGEIFAQGTRDKILTENV 237
Cdd:PRK10771 147 EQPILLLDEPFSALDPALRqEMltLVSQVCQERQL----TLLMVSHSLEDAARIAPRSLVVADGRIAWDGPTDELLSGKA 222
|
|
| tauB |
PRK11248 |
taurine ABC transporter ATP-binding subunit; |
18-221 |
2.30e-16 |
|
taurine ABC transporter ATP-binding subunit;
Pssm-ID: 183056 [Multi-domain] Cd Length: 255 Bit Score: 76.28 E-value: 2.30e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 18 KIILKNINWSLHSGENWVLMGLNGAGKTTLLSLIYGNHWATTGSIevlgeTFGKTNVLALKKRIGLIstavqsqFPEHHL 97
Cdd:PRK11248 14 KPALEDINLTLESGELLVVLGPSGCGKTTLLNLIAGFVPYQHGSI-----TLDGKPVEGPGAERGVV-------FQNEGL 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 98 A--QYIVLSGKFGT--IGIHNDfekNDLNEAIGLLKKLGGDELVNKPYRVLSQGQRQLVLIARALLGKPELLILDEPCNG 173
Cdd:PRK11248 82 LpwRNVQDNVAFGLqlAGVEKM---QRLEIAHQMLKKVGLEGAEKRYIWQLSGGQRQRVGIARALAANPQLLLLDEPFGA 158
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 915796356 174 LDLFSRELLLEQINKLAQLPNHPTLLfVSHYTEEILPIFKNIMLLKQG 221
Cdd:PRK11248 159 LDAFTREQMQTLLLKLWQETGKQVLL-ITHDIEEAVFMATELVLLSPG 205
|
|
| fecE |
PRK11231 |
Fe(3+) dicitrate ABC transporter ATP-binding protein FecE; |
17-250 |
2.81e-16 |
|
Fe(3+) dicitrate ABC transporter ATP-binding protein FecE;
Pssm-ID: 183044 [Multi-domain] Cd Length: 255 Bit Score: 75.82 E-value: 2.81e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 17 DKIILKNINWSLHSGENWVLMGLNGAGKTTLLSLIYGNHWATTGSIEVLGETFGKTNVLALKKRIGLIstavqsqfPEHH 96
Cdd:PRK11231 14 TKRILNDLSLSLPTGKITALIGPNGCGKSTLLKCFARLLTPQSGTVFLGDKPISMLSSRQLARRLALL--------PQHH 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 97 LAQ---------------YIVLSGKFGTigihNDFEKndLNEAiglLKKLGGDELVNKPYRVLSQGQRQLVLIARALLGK 161
Cdd:PRK11231 86 LTPegitvrelvaygrspWLSLWGRLSA----EDNAR--VNQA---MEQTRINHLADRRLTDLSGGQRQRAFLAMVLAQD 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 162 PELLILDEPCNGLDLFSRELLLEQINKLAQlpNHPTLLFVSHYTEEILPIFKNIMLLKQGEIFAQGTRDKILTENVLSKF 241
Cdd:PRK11231 157 TPVVLLDEPTTYLDINHQVELMRLMRELNT--QGKTVVTVLHDLNQASRYCDHLVVLANGHVMAQGTPEEVMTPGLLRTV 234
|
....*....
gi 915796356 242 YPKPIKIFP 250
Cdd:PRK11231 235 FDVEAEIHP 243
|
|
| cbiO |
PRK13640 |
energy-coupling factor transporter ATPase; |
1-240 |
3.70e-16 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184200 [Multi-domain] Cd Length: 282 Bit Score: 75.99 E-value: 3.70e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 1 MTNNAVlSMKNVSF---ERDKIILKNINWSLHSGENWVLMGLNGAGKTTLLSLIYG---NHWATTGSIEVLGETFGKTNV 74
Cdd:PRK13640 1 MKDNIV-EFKHVSFtypDSKKPALNDISFSIPRGSWTALIGHNGSGKSTISKLINGlllPDDNPNSKITVDGITLTAKTV 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 75 LALKKRIGLIStavqsQFPEHHLAQYIVlsGKFGTIGIHN-DFEKNDLNEAIG-LLKKLGGDELVNKPYRVLSQGQRQLV 152
Cdd:PRK13640 80 WDIREKVGIVF-----QNPDNQFVGATV--GDDVAFGLENrAVPRPEMIKIVRdVLADVGMLDYIDSEPANLSGGQKQRV 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 153 LIARALLGKPELLILDEPCNGLDLFSRELLLEQINKLaQLPNHPTLLFVSHYTEEIlPIFKNIMLLKQGEIFAQGTRDKI 232
Cdd:PRK13640 153 AIAGILAVEPKIIILDESTSMLDPAGKEQILKLIRKL-KKKNNLTVISITHDIDEA-NMADQVLVLDDGKLLAQGSPVEI 230
|
....*...
gi 915796356 233 LTENVLSK 240
Cdd:PRK13640 231 FSKVEMLK 238
|
|
| hmuV |
PRK13547 |
heme ABC transporter ATP-binding protein; |
14-247 |
5.89e-16 |
|
heme ABC transporter ATP-binding protein;
Pssm-ID: 184132 [Multi-domain] Cd Length: 272 Bit Score: 75.25 E-value: 5.89e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 14 FERDKIILKNINWSLHSGENWVLMGLNGAGKTTLLSLIYG--------NHWATTGSIEVLGETFGKTNVLALKKRIGLIS 85
Cdd:PRK13547 10 ARRHRAILRDLSLRIEPGRVTALLGRNGAGKSTLLKALAGdltgggapRGARVTGDVTLNGEPLAAIDAPRLARLRAVLP 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 86 TAVQSQFPehHLAQYIVLSGKFGTIGIHNDFEKNDLNEAIGLLKKLGGDELVNKPYRVLSQGQRQLVLIARAL------- 158
Cdd:PRK13547 90 QAAQPAFA--FSAREIVLLGRYPHARRAGALTHRDGEIAWQALALAGATALVGRDVTTLSGGELARVQFARVLaqlwpph 167
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 159 --LGKPELLILDEPCNGLDLFSRELLLEQINKLAQLPNHPTLLFVsHYTEEILPIFKNIMLLKQGEIFAQGTRDKILTEN 236
Cdd:PRK13547 168 daAQPPRYLLLDEPTAALDLAHQHRLLDTVRRLARDWNLGVLAIV-HDPNLAARHADRIAMLADGAIVAHGAPADVLTPA 246
|
250
....*....|.
gi 915796356 237 VLSKFYPKPIK 247
Cdd:PRK13547 247 HIARCYGFAVR 257
|
|
| DppD |
COG0444 |
ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid ... |
6-203 |
6.55e-16 |
|
ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];
Pssm-ID: 440213 [Multi-domain] Cd Length: 320 Bit Score: 75.86 E-value: 6.55e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 6 VLSMKN--VSFERDKIILK---NINWSLHSGENWVLMGLNGAGKTTLLSLIYG---NHWATTGSIEVLGEtfgktNVLAL 77
Cdd:COG0444 1 LLEVRNlkVYFPTRRGVVKavdGVSFDVRRGETLGLVGESGSGKSTLARAILGllpPPGITSGEILFDGE-----DLLKL 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 78 K---------KRIGLI----STA------VQSQFPEhhlaqyivlsgkfgTIGIHNDFEKNDLNE-AIGLLKKLGgdelV 137
Cdd:COG0444 76 SekelrkirgREIQMIfqdpMTSlnpvmtVGDQIAE--------------PLRIHGGLSKAEARErAIELLERVG----L 137
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 915796356 138 NKPYRV-------LSQGQRQLVLIARALLGKPELLILDEPCNGLDLFSRELLLEQINKLAQ---LpnhpTLLFVSH 203
Cdd:COG0444 138 PDPERRldrypheLSGGMRQRVMIARALALEPKLLIADEPTTALDVTIQAQILNLLKDLQRelgL----AILFITH 209
|
|
| cbiO |
PRK13638 |
energy-coupling factor ABC transporter ATP-binding protein; |
16-227 |
7.94e-16 |
|
energy-coupling factor ABC transporter ATP-binding protein;
Pssm-ID: 184198 [Multi-domain] Cd Length: 271 Bit Score: 75.04 E-value: 7.94e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 16 RDKIILK--NINWSLHSGENwvLMGLNGAGKTTLLSLIYGNHWATTGSIEVLGET--FGKTNVLALKKRIGLISTAVQSQ 91
Cdd:PRK13638 12 QDEPVLKglNLDFSLSPVTG--LVGANGCGKSTLFMNLSGLLRPQKGAVLWQGKPldYSKRGLLALRQQVATVFQDPEQQ 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 92 FPEHHLAQYIVLSGKfgTIGIHNDFEKNDLNEAIGLLKKLGgdeLVNKPYRVLSQGQRQLVLIARALLGKPELLILDEPC 171
Cdd:PRK13638 90 IFYTDIDSDIAFSLR--NLGVPEAEITRRVDEALTLVDAQH---FRHQPIQCLSHGQKKRVAIAGALVLQARYLLLDEPT 164
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 915796356 172 NGLDLFSRELLLEQINKLAQLPNHptLLFVSHYTEEILPIFKNIMLLKQGEIFAQG 227
Cdd:PRK13638 165 AGLDPAGRTQMIAIIRRIVAQGNH--VIISSHDIDLIYEISDAVYVLRQGQILTHG 218
|
|
| ArpD |
COG4618 |
ABC-type protease/lipase transport system, ATPase and permease components [Intracellular ... |
7-233 |
8.39e-16 |
|
ABC-type protease/lipase transport system, ATPase and permease components [Intracellular trafficking, secretion, and vesicular transport];
Pssm-ID: 443660 [Multi-domain] Cd Length: 563 Bit Score: 76.71 E-value: 8.39e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 7 LSMKNVSF---ERDKIILKNINWSLHSGENWVLMGLNGAGKTTLLSLIYGNHWATTGSIEVLGETFGKTNVLALKKRIGl 83
Cdd:COG4618 331 LSVENLTVvppGSKRPILRGVSFSLEPGEVLGVIGPSGSGKSTLARLLVGVWPPTAGSVRLDGADLSQWDREELGRHIG- 409
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 84 istavqsqfpehHLAQYIVLsgkF-GTI----------------------GIHndfekndlnEAIGLLKKlGGDELVNKP 140
Cdd:COG4618 410 ------------YLPQDVEL---FdGTIaeniarfgdadpekvvaaaklaGVH---------EMILRLPD-GYDTRIGEG 464
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 141 YRVLSQGQRQLVLIARALLGKPELLILDEPCNGLDLFSRELLLEQINKLAQlpNHPTLLFVSHYTeEILPIFKNIMLLKQ 220
Cdd:COG4618 465 GARLSGGQRQRIGLARALYGDPRLVVLDEPNSNLDDEGEAALAAAIRALKA--RGATVVVITHRP-SLLAAVDKLLVLRD 541
|
250
....*....|...
gi 915796356 221 GEIFAQGTRDKIL 233
Cdd:COG4618 542 GRVQAFGPRDEVL 554
|
|
| btuD |
PRK09536 |
corrinoid ABC transporter ATPase; Reviewed |
7-238 |
1.04e-15 |
|
corrinoid ABC transporter ATPase; Reviewed
Pssm-ID: 236554 [Multi-domain] Cd Length: 402 Bit Score: 76.03 E-value: 1.04e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 7 LSMKNVSFER-DKIILKNINWSLHSGENWVLMGLNGAGKTTLLSLIYGNHWATTGSIEVLGETFGKTNVLALKKRIGLI- 84
Cdd:PRK09536 4 IDVSDLSVEFgDTTVLDGVDLSVREGSLVGLVGPNGAGKTTLLRAINGTLTPTAGTVLVAGDDVEALSARAASRRVASVp 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 85 -STAVQSQFPehhlAQYIVLSGK---FGTIGIHNDFEKNDLNEAIgllKKLGGDELVNKPYRVLSQGQRQLVLIARALLG 160
Cdd:PRK09536 84 qDTSLSFEFD----VRQVVEMGRtphRSRFDTWTETDRAAVERAM---ERTGVAQFADRPVTSLSGGERQRVLLARALAQ 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 161 KPELLILDEPCNGLDLFSRELLLEQINKLAQlpNHPTLLFVSH-------YTEEILpifknimLLKQGEIFAQGTRDKIL 233
Cdd:PRK09536 157 ATPVLLLDEPTASLDINHQVRTLELVRRLVD--DGKTAVAAIHdldlaarYCDELV-------LLADGRVRAAGPPADVL 227
|
....*
gi 915796356 234 TENVL 238
Cdd:PRK09536 228 TADTL 232
|
|
| SufC |
COG0396 |
Fe-S cluster assembly ATPase SufC [Posttranslational modification, protein turnover, ... |
7-230 |
1.35e-15 |
|
Fe-S cluster assembly ATPase SufC [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 440165 [Multi-domain] Cd Length: 245 Bit Score: 73.95 E-value: 1.35e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 7 LSMKNVSFE-RDKIILKNINWSLHSGENWVLMGLNGAGKTTLLSLIYGN--HWATTGSIEVLGEtfgktNVLAL------ 77
Cdd:COG0396 1 LEIKNLHVSvEGKEILKGVNLTIKPGEVHAIMGPNGSGKSTLAKVLMGHpkYEVTSGSILLDGE-----DILELspdera 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 78 KKRIGL----------------ISTAVQSQF-PEHHLAQYI-VLSGKFGTIGIHNDFEKNDLNEAigllkklggdelvnk 139
Cdd:COG0396 76 RAGIFLafqypveipgvsvsnfLRTALNARRgEELSAREFLkLLKEKMKELGLDEDFLDRYVNEG--------------- 140
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 140 pyrvLSQGQRQLVLIARALLGKPELLILDEPCNGLDLFSRELLLEQINKLAQlpNHPTLLFVSHYT---EEILPIFknIM 216
Cdd:COG0396 141 ----FSGGEKKRNEILQMLLLEPKLAILDETDSGLDIDALRIVAEGVNKLRS--PDRGILIITHYQrilDYIKPDF--VH 212
|
250
....*....|....
gi 915796356 217 LLKQGEIFAQGTRD 230
Cdd:COG0396 213 VLVDGRIVKSGGKE 226
|
|
| ABC_MetN_methionine_transporter |
cd03258 |
ATP-binding cassette domain of methionine transporter; MetN (also known as YusC) is an ... |
6-228 |
1.39e-15 |
|
ATP-binding cassette domain of methionine transporter; MetN (also known as YusC) is an ABC-type transporter encoded by metN of the metNPQ operon in Bacillus subtilis that is involved in methionine transport. Other members of this system include the MetP permease and the MetQ substrate binding protein. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213225 [Multi-domain] Cd Length: 233 Bit Score: 73.77 E-value: 1.39e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 6 VLSMKNVS--FE---RDKIILKNINWSLHSGENWVLMGLNGAGKTTLLSLIYGNHWATTGSIEVLGE---TFGKTNVLAL 77
Cdd:cd03258 1 MIELKNVSkvFGdtgGKVTALKDVSLSVPKGEIFGIIGRSGAGKSTLIRCINGLERPTSGSVLVDGTdltLLSGKELRKA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 78 KKRIGLISTavqsqfpehhlaQYIVLSGK--FGTIG----IHNdFEKNDLNEAIGLLKKLGGDELVNKPY-RVLSQGQRQ 150
Cdd:cd03258 81 RRRIGMIFQ------------HFNLLSSRtvFENVAlpleIAG-VPKAEIEERVLELLELVGLEDKADAYpAQLSGGQKQ 147
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 151 LVLIARALLGKPELLILDEPCNGLDLFSRE---LLLEQINKLAQLpnhpTLLFVSHYTEEILPIFKNIMLLKQGEIFAQG 227
Cdd:cd03258 148 RVGIARALANNPKVLLCDEATSALDPETTQsilALLRDINRELGL----TIVLITHEMEVVKRICDRVAVMEKGEVVEEG 223
|
.
gi 915796356 228 T 228
Cdd:cd03258 224 T 224
|
|
| cbiO |
PRK13636 |
cobalt transporter ATP-binding subunit; Provisional |
21-235 |
1.53e-15 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 184196 [Multi-domain] Cd Length: 283 Bit Score: 74.50 E-value: 1.53e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 21 LKNINWSLHSGENWVLMGLNGAGKTTLLSLIYGNHWATTGSIEVLGET--FGKTNVLALKKRIGLIStavqsQFPEHHLA 98
Cdd:PRK13636 22 LKGININIKKGEVTAILGGNGAGKSTLFQNLNGILKPSSGRILFDGKPidYSRKGLMKLRESVGMVF-----QDPDNQLF 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 99 QYIVLSG-KFGTIGIHndFEKNDLNEAI-GLLKKLGGDELVNKPYRVLSQGQRQLVLIARALLGKPELLILDEPCNGLDL 176
Cdd:PRK13636 97 SASVYQDvSFGAVNLK--LPEDEVRKRVdNALKRTGIEHLKDKPTHCLSFGQKKRVAIAGVLVMEPKVLVLDEPTAGLDP 174
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 915796356 177 FS----RELLLEQINKLAQlpnhpTLLFVSHYTeEILPIF-KNIMLLKQGEIFAQGTRDKILTE 235
Cdd:PRK13636 175 MGvseiMKLLVEMQKELGL-----TIIIATHDI-DIVPLYcDNVFVMKEGRVILQGNPKEVFAE 232
|
|
| PRK10851 |
PRK10851 |
sulfate/thiosulfate ABC transporter ATP-binding protein CysA; |
11-232 |
1.56e-15 |
|
sulfate/thiosulfate ABC transporter ATP-binding protein CysA;
Pssm-ID: 182778 [Multi-domain] Cd Length: 353 Bit Score: 75.12 E-value: 1.56e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 11 NVSFERDKIiLKNINWSLHSGENWVLMGLNGAGKTTLLSLIYGNHWATTGSIEVLGETFGKtnVLALKKRIGLIstavqs 90
Cdd:PRK10851 9 KKSFGRTQV-LNDISLDIPSGQMVALLGPSGSGKTTLLRIIAGLEHQTSGHIRFHGTDVSR--LHARDRKVGFV------ 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 91 qFPEHHLAQYIVLsgkFGTI--GIHNDFEKNDLNEAI------GLLKKLGGDELVNKPYRVLSQGQRQLVLIARALLGKP 162
Cdd:PRK10851 80 -FQHYALFRHMTV---FDNIafGLTVLPRRERPNAAAikakvtQLLEMVQLAHLADRYPAQLSGGQKQRVALARALAVEP 155
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 915796356 163 ELLILDEPCNGLDLFSRELLLEQINKLaqlpnHPTL----LFVSHYTEEILPIFKNIMLLKQGEIFAQGTRDKI 232
Cdd:PRK10851 156 QILLLDEPFGALDAQVRKELRRWLRQL-----HEELkftsVFVTHDQEEAMEVADRVVVMSQGNIEQAGTPDQV 224
|
|
| cbiO |
PRK13643 |
energy-coupling factor transporter ATPase; |
21-235 |
2.09e-15 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184203 [Multi-domain] Cd Length: 288 Bit Score: 74.00 E-value: 2.09e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 21 LKNINWSLHSGENWVLMGLNGAGKTTLLSLIYGNHWATTGSIEV----LGETFGKTNVLALKKRIGLIStavqsQFPEHH 96
Cdd:PRK13643 22 LFDIDLEVKKGSYTALIGHTGSGKSTLLQHLNGLLQPTEGKVTVgdivVSSTSKQKEIKPVRKKVGVVF-----QFPESQ 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 97 LAQYIVLSG-KFG--TIGIHNDFEKN---DLNEAIGLLKklggdELVNKPYRVLSQGQRQLVLIARALLGKPELLILDEP 170
Cdd:PRK13643 97 LFEETVLKDvAFGpqNFGIPKEKAEKiaaEKLEMVGLAD-----EFWEKSPFELSGGQMRRVAIAGILAMEPEVLVLDEP 171
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 915796356 171 CNGLDLFSR-EL--LLEQINKLAQlpnhpTLLFVSHYTEEILPIFKNIMLLKQGEIFAQGTRDKILTE 235
Cdd:PRK13643 172 TAGLDPKARiEMmqLFESIHQSGQ-----TVVLVTHLMDDVADYADYVYLLEKGHIISCGTPSDVFQE 234
|
|
| PRK15439 |
PRK15439 |
autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional |
20-244 |
2.40e-15 |
|
autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional
Pssm-ID: 185336 [Multi-domain] Cd Length: 510 Bit Score: 75.09 E-value: 2.40e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 20 ILKNINWSLHSGENWVLMGLNGAGKTTLLSLIYGNHWATTGSIEVLGETFGK-TNVLALKKRIGLIStavQSQ--FPEHH 96
Cdd:PRK15439 26 VLKGIDFTLHAGEVHALLGGNGAGKSTLMKIIAGIVPPDSGTLEIGGNPCARlTPAKAHQLGIYLVP---QEPllFPNLS 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 97 LAQYIVlsgkFGTIGIHNDFEKndLNEaigLLKKLGGDELVNKPYRVLSQGQRQLVLIARALLGKPELLILDEPCNGLDL 176
Cdd:PRK15439 103 VKENIL----FGLPKRQASMQK--MKQ---LLAALGCQLDLDSSAGSLEVADRQIVEILRGLMRDSRILILDEPTASLTP 173
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 915796356 177 FSRELLLEQINKLAQLPNhpTLLFVSHYTEEILPIFKNIMLLKQGEIFAQGTRDKILTENVLSKFYPK 244
Cdd:PRK15439 174 AETERLFSRIRELLAQGV--GIVFISHKLPEIRQLADRISVMRDGTIALSGKTADLSTDDIIQAITPA 239
|
|
| PRK11160 |
PRK11160 |
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed |
2-235 |
2.98e-15 |
|
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed
Pssm-ID: 236865 [Multi-domain] Cd Length: 574 Bit Score: 74.86 E-value: 2.98e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 2 TNNAVLSMKNVSF---ERDKIILKNINWSLHSGENWVLMGLNGAGKTTLLSLIYGNHWATTGSIEVLGETFGKTNVLALK 78
Cdd:PRK11160 334 ADQVSLTLNNVSFtypDQPQPVLKGLSLQIKAGEKVALLGRTGCGKSTLLQLLTRAWDPQQGEILLNGQPIADYSEAALR 413
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 79 KRIGLISTAVqsqfpehHLaqyivLSGKFG---TIGIHNdfeKNDlNEAIGLLKKLGGDELVNKPY----------RVLS 145
Cdd:PRK11160 414 QAISVVSQRV-------HL-----FSATLRdnlLLAAPN---ASD-EALIEVLQQVGLEKLLEDDKglnawlgeggRQLS 477
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 146 QGQRQLVLIARALLGKPELLILDEPCNGLDLFSRELLLEQINKLAQlpnHPTLLFVSHYTEEiLPIFKNIMLLKQGEIFA 225
Cdd:PRK11160 478 GGEQRRLGIARALLHDAPLLLLDEPTEGLDAETERQILELLAEHAQ---NKTVLMITHRLTG-LEQFDRICVMDNGQIIE 553
|
250
....*....|
gi 915796356 226 QGTRDKILTE 235
Cdd:PRK11160 554 QGTHQELLAQ 563
|
|
| NupO |
COG3845 |
ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and ... |
2-209 |
3.22e-15 |
|
ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and metabolism];
Pssm-ID: 443055 [Multi-domain] Cd Length: 504 Bit Score: 74.68 E-value: 3.22e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 2 TNNAVLSMKNVSferdK-----IILKNINWSLHSGENWVLMGLNGAGKTTLLSLIYGNHWATTGSIEVLGE--TFGKTNV 74
Cdd:COG3845 1 MMPPALELRGIT----KrfggvVANDDVSLTVRPGEIHALLGENGAGKSTLMKILYGLYQPDSGEILIDGKpvRIRSPRD 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 75 lALKKRIGLIStavQ--SQFPEHHLAQYIVLS---GKFGTIgihndfeknDLNEAIGLLKKLGG--------DELVNKpy 141
Cdd:COG3845 77 -AIALGIGMVH---QhfMLVPNLTVAENIVLGlepTKGGRL---------DRKAARARIRELSErygldvdpDAKVED-- 141
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 915796356 142 rvLSQGQRQLVLIARALLGKPELLILDEPCNGLDLFSRELLLEQINKLAQlpNHPTLLFVSHYTEEIL 209
Cdd:COG3845 142 --LSVGEQQRVEILKALYRGARILILDEPTAVLTPQEADELFEILRRLAA--EGKSIIFITHKLREVM 205
|
|
| PRK10070 |
PRK10070 |
proline/glycine betaine ABC transporter ATP-binding protein ProV; |
21-233 |
3.24e-15 |
|
proline/glycine betaine ABC transporter ATP-binding protein ProV;
Pssm-ID: 182221 [Multi-domain] Cd Length: 400 Bit Score: 74.68 E-value: 3.24e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 21 LKNINWSLHSGENWVLMGLNGAGKTTLLSLIYGNHWATTGSIEVLGETFGKTNVLALKK-RIGLISTAVQS--QFPEHHL 97
Cdd:PRK10070 44 VKDASLAIEEGEIFVIMGLSGSGKSTMVRLLNRLIEPTRGQVLIDGVDIAKISDAELREvRRKKIAMVFQSfaLMPHMTV 123
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 98 AQYIVLSGKFGTIGIHNDFEKndlneAIGLLKKLGGDELVNKPYRVLSQGQRQLVLIARALLGKPELLILDEPCNGLDLF 177
Cdd:PRK10070 124 LDNTAFGMELAGINAEERREK-----ALDALRQVGLENYAHSYPDELSGGMRQRVGLARALAINPDILLMDEAFSALDPL 198
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 915796356 178 SRELLLEQINKLaQLPNHPTLLFVSHYTEEILPIFKNIMLLKQGEIFAQGTRDKIL 233
Cdd:PRK10070 199 IRTEMQDELVKL-QAKHQRTIVFISHDLDEAMRIGDRIAIMQNGEVVQVGTPDEIL 253
|
|
| LivF |
COG0410 |
ABC-type branched-chain amino acid transport system, ATPase component LivF [Amino acid ... |
5-242 |
3.49e-15 |
|
ABC-type branched-chain amino acid transport system, ATPase component LivF [Amino acid transport and metabolism];
Pssm-ID: 440179 [Multi-domain] Cd Length: 236 Bit Score: 72.71 E-value: 3.49e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 5 AVLSMKNVSFERDKI-ILKNINWSLHSGENWVLMGLNGAGKTTLLSLIYGNHWATTGSIEVLGE--TFGKTNVLAlKKRI 81
Cdd:COG0410 2 PMLEVENLHAGYGGIhVLHGVSLEVEEGEIVALLGRNGAGKTTLLKAISGLLPPRSGSIRFDGEdiTGLPPHRIA-RLGI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 82 GLIstavqsqfPEHH-------------LAQYIVLSGKfgtiGIHNDFEKN-----DLNEaigLLKKLGGDelvnkpyrv 143
Cdd:COG0410 81 GYV--------PEGRrifpsltveenllLGAYARRDRA----EVRADLERVyelfpRLKE---RRRQRAGT--------- 136
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 144 LSQGQRQLVLIARALLGKPELLILDEPCNGL------DLFSrelLLEQINKLAQlpnhpTLLFVSHYTEEILPIFKNIML 217
Cdd:COG0410 137 LSGGEQQMLAIGRALMSRPKLLLLDEPSLGLapliveEIFE---IIRRLNREGV-----TILLVEQNARFALEIADRAYV 208
|
250 260
....*....|....*....|....*
gi 915796356 218 LKQGEIFAQGTRDKILTENVLSKFY 242
Cdd:COG0410 209 LERGRIVLEGTAAELLADPEVREAY 233
|
|
| ABCC_Hemolysin |
cd03252 |
ATP-binding cassette domain of hemolysin B, subfamily C; The ABC-transporter hemolysin B is a ... |
20-236 |
3.90e-15 |
|
ATP-binding cassette domain of hemolysin B, subfamily C; The ABC-transporter hemolysin B is a central component of the secretion machinery that translocates the toxin, hemolysin A, in a Sec-independent fashion across both membranes of E. coli. The hemolysin A (HlyA) transport machinery is composed of the ATP-binding cassette (ABC) transporter HlyB located in the inner membrane, hemolysin D (HlyD), also anchored in the inner membrane, and TolC, which resides in the outer membrane. HlyD apparently forms a continuous channel that bridges the entire periplasm, interacting with TolC and HlyB. This arrangement prevents the appearance of periplasmic intermediates of HlyA during substrate transport. Little is known about the molecular details of HlyA transport, but it is evident that ATP-hydrolysis by the ABC-transporter HlyB is a necessary source of energy.
Pssm-ID: 213219 [Multi-domain] Cd Length: 237 Bit Score: 72.52 E-value: 3.90e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 20 ILKNINWSLHSGENWVLMGLNGAGKTTLLSLIYGNHWATTGSIEVLGETFGKTNVLALKKRIGLIstaVQSQ-FPEHHLA 98
Cdd:cd03252 17 ILDNISLRIKPGEVVGIVGRSGSGKSTLTKLIQRFYVPENGRVLVDGHDLALADPAWLRRQVGVV---LQENvLFNRSIR 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 99 QYIVLSGKfgTIGIHNDFEKNDLNEAIGLLKKL--GGDELVNKPYRVLSQGQRQLVLIARALLGKPELLILDEPCNGLDL 176
Cdd:cd03252 94 DNIALADP--GMSMERVIEAAKLAGAHDFISELpeGYDTIVGEQGAGLSGGQRQRIAIARALIHNPRILIFDEATSALDY 171
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 177 FSRELLLEQINKLAQlpnHPTLLFVSHYTEEILPIFKnIMLLKQGEIFAQGTRDKILTEN 236
Cdd:cd03252 172 ESEHAIMRNMHDICA---GRTVIIIAHRLSTVKNADR-IIVMEKGRIVEQGSHDELLAEN 227
|
|
| YddA |
COG4178 |
ABC-type uncharacterized transport system, permease and ATPase components [General function ... |
2-203 |
4.30e-15 |
|
ABC-type uncharacterized transport system, permease and ATPase components [General function prediction only];
Pssm-ID: 443337 [Multi-domain] Cd Length: 571 Bit Score: 74.46 E-value: 4.30e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 2 TNNAVLSMKNVSFER--DKIILKNINWSLHSGENWVLMGLNGAGKTTLLSLIYGnHW-ATTGSIevlgetfgktnvlalk 78
Cdd:COG4178 358 SEDGALALEDLTLRTpdGRPLLEDLSLSLKPGERLLITGPSGSGKSTLLRAIAG-LWpYGSGRI---------------- 420
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 79 kriglistavqsQFPEHH----LAQ--YIVLsgkfGTI-------GIHNDFEKNDLNEAiglLKKLGGDELVNKPY---- 141
Cdd:COG4178 421 ------------ARPAGArvlfLPQrpYLPL----GTLreallypATAEAFSDAELREA---LEAVGLGHLAERLDeead 481
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 915796356 142 --RVLSQGQRQLVLIARALLGKPELLILDEPCNGLDLFSRELLLEQInkLAQLPNhPTLLFVSH 203
Cdd:COG4178 482 wdQVLSLGEQQRLAFARLLLHKPDWLFLDEATSALDEENEAALYQLL--REELPG-TTVISVGH 542
|
|
| PRK10619 |
PRK10619 |
histidine ABC transporter ATP-binding protein HisP; |
20-233 |
5.13e-15 |
|
histidine ABC transporter ATP-binding protein HisP;
Pssm-ID: 182592 [Multi-domain] Cd Length: 257 Bit Score: 72.69 E-value: 5.13e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 20 ILKNINWSLHSGENWVLMGLNGAGKTTLLSLIYGNHWATTGSIEVLGETF-------GKTNVlALKKRIGLISTAVQSQF 92
Cdd:PRK10619 20 VLKGVSLQANAGDVISIIGSSGSGKSTFLRCINFLEKPSEGSIVVNGQTInlvrdkdGQLKV-ADKNQLRLLRTRLTMVF 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 93 PEHHLAQYI-----VLSGKFGTIGIhndfEKNDLNE-AIGLLKKLGGDELVNKPYRV-LSQGQRQLVLIARALLGKPELL 165
Cdd:PRK10619 99 QHFNLWSHMtvlenVMEAPIQVLGL----SKQEARErAVKYLAKVGIDERAQGKYPVhLSGGQQQRVSIARALAMEPEVL 174
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 915796356 166 ILDEPCNGLDlfsRELLLEQINKLAQLPNH-PTLLFVSHYTEEILPIFKNIMLLKQGEIFAQGTRDKIL 233
Cdd:PRK10619 175 LFDEPTSALD---PELVGEVLRIMQQLAEEgKTMVVVTHEMGFARHVSSHVIFLHQGKIEEEGAPEQLF 240
|
|
| COG4674 |
COG4674 |
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ... |
2-232 |
6.21e-15 |
|
ABC-type uncharacterized transport system, ATPase component [General function prediction only];
Pssm-ID: 443710 [Multi-domain] Cd Length: 250 Bit Score: 72.07 E-value: 6.21e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 2 TNNAVLSMKNVSFERD--KIiLKNINWSLHSGENWVLMGLNGAGKTTLLSLIYGNHWATTGSIEvlgetFGKTNVLALKK 79
Cdd:COG4674 6 MHGPILYVEDLTVSFDgfKA-LNDLSLYVDPGELRVIIGPNGAGKTTLMDVITGKTRPDSGSVL-----FGGTDLTGLDE 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 80 ----RIGlISTAVQ--SQFPEHHLAQYIVLSGK-----FGTIGIHNDFEKND----LNEAIGLLKKLggdelvNKPYRVL 144
Cdd:COG4674 80 heiaRLG-IGRKFQkpTVFEELTVFENLELALKgdrgvFASLFARLTAEERDrieeVLETIGLTDKA------DRLAGLL 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 145 SQGQRQLVLIARALLGKPELLILDEPCNGLDLFSRELLLEQINKLAQlpNHpTLLFVSHYTEEILPIFKNIMLLKQGEIF 224
Cdd:COG4674 153 SHGQKQWLEIGMLLAQDPKLLLLDEPVAGMTDAETERTAELLKSLAG--KH-SVVVVEHDMEFVRQIARKVTVLHQGSVL 229
|
....*...
gi 915796356 225 AQGTRDKI 232
Cdd:COG4674 230 AEGSLDEV 237
|
|
| cbiO |
PRK13650 |
energy-coupling factor transporter ATPase; |
1-223 |
7.71e-15 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184209 [Multi-domain] Cd Length: 279 Bit Score: 72.46 E-value: 7.71e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 1 MTNnaVLSMKNVSF----ERDKIILKNINWSLHSGENWVLMGLNGAGKTTLLSLIYGNHWATTGSIEVLGETFGKTNVLA 76
Cdd:PRK13650 1 MSN--IIEVKNLTFkykeDQEKYTLNDVSFHVKQGEWLSIIGHNGSGKSTTVRLIDGLLEAESGQIIIDGDLLTEENVWD 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 77 LKKRIGLISTAVQSQF----PEHHLAqyivlsgkFG--TIGIHNDFEKNDLNEAIGLlkkLGGDELVNKPYRVLSQGQRQ 150
Cdd:PRK13650 79 IRHKIGMVFQNPDNQFvgatVEDDVA--------FGleNKGIPHEEMKERVNEALEL---VGMQDFKEREPARLSGGQKQ 147
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 915796356 151 LVLIARALLGKPELLILDEPCNGLDLFSRELLLEQINKLAQlPNHPTLLFVSHYTEEIlPIFKNIMLLKQGEI 223
Cdd:PRK13650 148 RVAIAGAVAMRPKIIILDEATSMLDPEGRLELIKTIKGIRD-DYQMTVISITHDLDEV-ALSDRVLVMKNGQV 218
|
|
| livG |
PRK11300 |
leucine/isoleucine/valine transporter ATP-binding subunit; Provisional |
23-232 |
8.09e-15 |
|
leucine/isoleucine/valine transporter ATP-binding subunit; Provisional
Pssm-ID: 183080 [Multi-domain] Cd Length: 255 Bit Score: 71.94 E-value: 8.09e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 23 NINWSLHSGENWVLMGLNGAGKTTLLSLIYGNHWATTGSIEVLGE-----------------TFgkTNVlALKKRIGLIS 85
Cdd:PRK11300 23 NVNLEVREQEIVSLIGPNGAGKTTVFNCLTGFYKPTGGTILLRGQhieglpghqiarmgvvrTF--QHV-RLFREMTVIE 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 86 TAVQSQfpeHHLAQYIVLSGKFGTIGIHNDfEKNDLNEAIGLLKKLGGDELVNKPYRVLSQGQRQLVLIARALLGKPELL 165
Cdd:PRK11300 100 NLLVAQ---HQQLKTGLFSGLLKTPAFRRA-ESEALDRAATWLERVGLLEHANRQAGNLAYGQQRRLEIARCMVTQPEIL 175
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 915796356 166 ILDEPCNGLDLFSRELLLEQINKLAQLPNhPTLLFVSHYTEEILPIFKNIMLLKQGEIFAQGTRDKI 232
Cdd:PRK11300 176 MLDEPAAGLNPKETKELDELIAELRNEHN-VTVLLIEHDMKLVMGISDRIYVVNQGTPLANGTPEEI 241
|
|
| ABC_MTABC3_MDL1_MDL2 |
cd03249 |
ATP-binding cassette domain of a mitochondrial protein MTABC3 and related proteins; MTABC3 ... |
9-190 |
1.14e-14 |
|
ATP-binding cassette domain of a mitochondrial protein MTABC3 and related proteins; MTABC3 (also known as ABCB6) is a mitochondrial ATP-binding cassette protein involved in iron homeostasis and one of four ABC transporters expressed in the mitochondrial inner membrane, the other three being MDL1(ABC7), MDL2, and ATM1. In fact, the yeast MDL1 (multidrug resistance-like protein 1) and MDL2 (multidrug resistance-like protein 2) transporters are also included in this CD. MDL1 is an ATP-dependent permease that acts as a high-copy suppressor of ATM1 and is thought to have a role in resistance to oxidative stress. Interestingly, subfamily B is more closely related to the carboxyl-terminal component of subfamily C than the two halves of ABCC molecules are with one another.
Pssm-ID: 213216 [Multi-domain] Cd Length: 238 Bit Score: 71.03 E-value: 1.14e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 9 MKNVSF---ER-DKIILKNINWSLHSGENWVLMGLNGAGKTTLLSLI---YGnhwATTGSIEVLGETFGKTNVLALKKRI 81
Cdd:cd03249 3 FKNVSFrypSRpDVPILKGLSLTIPPGKTVALVGSSGCGKSTVVSLLerfYD---PTSGEILLDGVDIRDLNLRWLRSQI 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 82 GLIStavqsQFPehhlaqyIVLSG------KFGTigihNDFEKNDLNEAIGL------LKKL--GGDELVNKPYRVLSQG 147
Cdd:cd03249 80 GLVS-----QEP-------VLFDGtiaeniRYGK----PDATDEEVEEAAKKanihdfIMSLpdGYDTLVGERGSQLSGG 143
|
170 180 190 200
....*....|....*....|....*....|....*....|...
gi 915796356 148 QRQLVLIARALLGKPELLILDEPCNGLDLFSRELLLEQINKLA 190
Cdd:cd03249 144 QKQRIAIARALLRNPKILLLDEATSALDAESEKLVQEALDRAM 186
|
|
| GlnQ |
COG1126 |
ABC-type polar amino acid transport system, ATPase component [Amino acid transport and ... |
6-175 |
1.21e-14 |
|
ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 440743 [Multi-domain] Cd Length: 239 Bit Score: 71.18 E-value: 1.21e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 6 VLSMKNV--SFErDKIILKNINWSLHSGENWVLMGLNGAGKTTLLSLIygNHW--ATTGSIEVLGETFG--KTNVLALKK 79
Cdd:COG1126 1 MIEIENLhkSFG-DLEVLKGISLDVEKGEVVVIIGPSGSGKSTLLRCI--NLLeePDSGTITVDGEDLTdsKKDINKLRR 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 80 RIGListaV-QS--QFPehH--------LAQYIVLSGKfgtigihndfeKNDLNE-AIGLLKKLGGDELVNK-PYRvLSQ 146
Cdd:COG1126 78 KVGM----VfQQfnLFP--HltvlenvtLAPIKVKKMS-----------KAEAEErAMELLERVGLADKADAyPAQ-LSG 139
|
170 180
....*....|....*....|....*....
gi 915796356 147 GQRQLVLIARALLGKPELLILDEPCNGLD 175
Cdd:COG1126 140 GQQQRVAIARALAMEPKVMLFDEPTSALD 168
|
|
| cbiO |
PRK13642 |
energy-coupling factor transporter ATPase; |
4-233 |
1.40e-14 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184202 [Multi-domain] Cd Length: 277 Bit Score: 71.66 E-value: 1.40e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 4 NAVLSMKNVSF----ERDKIILKNINWSLHSGEnWV-LMGLNGAGKTTLLSLIYGNHWATTGSIEVLGETFGKTNVLALK 78
Cdd:PRK13642 2 NKILEVENLVFkyekESDVNQLNGVSFSITKGE-WVsIIGQNGSGKSTTARLIDGLFEEFEGKVKIDGELLTAENVWNLR 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 79 KRIGLISTAVQSQFPEHHLAQYIVLSGKfgTIGIHNDFEKNDLNEAIGLLKKLggDELVNKPYRvLSQGQRQLVLIARAL 158
Cdd:PRK13642 81 RKIGMVFQNPDNQFVGATVEDDVAFGME--NQGIPREEMIKRVDEALLAVNML--DFKTREPAR-LSGGQKQRVAVAGII 155
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 915796356 159 LGKPELLILDEPCNGLDLFSRELLLEQINKLAQlPNHPTLLFVSHYTEEILPIfKNIMLLKQGEIFAQGTRDKIL 233
Cdd:PRK13642 156 ALRPEIIILDESTSMLDPTGRQEIMRVIHEIKE-KYQLTVLSITHDLDEAASS-DRILVMKAGEIIKEAAPSELF 228
|
|
| ABCG_PDR_domain2 |
cd03232 |
Second domain of the pleiotropic drug resistance-like (PDR) subfamily G of ATP-binding ... |
4-221 |
1.56e-14 |
|
Second domain of the pleiotropic drug resistance-like (PDR) subfamily G of ATP-binding cassette transporters; The pleiotropic drug resistance (PDR) is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. This PDR subfamily represents domain I of its (ABC-IM)2 organization. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds including sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213199 [Multi-domain] Cd Length: 192 Bit Score: 69.96 E-value: 1.56e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 4 NAVLSMKNVSFE-----RDKIILKNINWSLHSGENWVLMGLNGAGKTTLLSLIYGNhwATTGSIEvlGETF--GKTNVLA 76
Cdd:cd03232 1 GSVLTWKNLNYTvpvkgGKRQLLNNISGYVKPGTLTALMGESGAGKTTLLDVLAGR--KTAGVIT--GEILinGRPLDKN 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 77 LKKRIGlistavqsqFPEH---HLAQYIVlsgkfgtigihndfekndlNEAIGLLKKLggdelvnkpyRVLSQGQRQLVL 153
Cdd:cd03232 77 FQRSTG---------YVEQqdvHSPNLTV-------------------REALRFSALL----------RGLSVEQRKRLT 118
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 915796356 154 IARALLGKPELLILDEPCNGLDLFSRELLLEQINKLAqLPNHPTLLFVSHYTEEILPIFKNIMLLKQG 221
Cdd:cd03232 119 IGVELAAKPSILFLDEPTSGLDSQAAYNIVRFLKKLA-DSGQAILCTIHQPSASIFEKFDRLLLLKRG 185
|
|
| ArtP |
COG4161 |
ABC-type arginine transport system, ATPase component [Amino acid transport and metabolism]; |
20-228 |
1.62e-14 |
|
ABC-type arginine transport system, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 443326 [Multi-domain] Cd Length: 242 Bit Score: 70.81 E-value: 1.62e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 20 ILKNINWSLHSGENWVLMGLNGAGKTTLLSLIYGNHWATTGSIEVLGETF------GKTNVLALKKRIGLIstavqsqFP 93
Cdd:COG4161 17 ALFDINLECPSGETLVLLGPSGAGKSSLLRVLNLLETPDSGQLNIAGHQFdfsqkpSEKAIRLLRQKVGMV-------FQ 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 94 EHHLAQYIVLsgkfgtigIHNDFE----------KNDLNEAIGLLKKLGGDELVNKPYRVLSQGQRQLVLIARALLGKPE 163
Cdd:COG4161 90 QYNLWPHLTV--------MENLIEapckvlglskEQAREKAMKLLARLRLTDKADRFPLHLSGGQQQRVAIARALMMEPQ 161
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 915796356 164 LLILDEPCNGLDLFSRELLLEQINKLAQlpNHPTLLFVSHYTEEILPIFKNIMLLKQGEIFAQGT 228
Cdd:COG4161 162 VLLFDEPTAALDPEITAQVVEIIRELSQ--TGITQVIVTHEVEFARKVASQVVYMEKGRIIEQGD 224
|
|
| PRK10575 |
PRK10575 |
Fe3+-hydroxamate ABC transporter ATP-binding protein FhuC; |
4-250 |
1.63e-14 |
|
Fe3+-hydroxamate ABC transporter ATP-binding protein FhuC;
Pssm-ID: 182561 [Multi-domain] Cd Length: 265 Bit Score: 71.36 E-value: 1.63e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 4 NAVLSMKNVSFE-RDKIILKNINWSLHSGENWVLMGLNGAGKTTLLSLIYGNHWATTGSIEVLGETFGKTNVLALKKRIG 82
Cdd:PRK10575 9 DTTFALRNVSFRvPGRTLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESWSSKAFARKVA 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 83 LIStavqSQFP--EHHLAQYIVLSGKF---GTIGIHNDFEKNDLNEAIGLLkklGGDELVNKPYRVLSQGQRQLVLIARA 157
Cdd:PRK10575 89 YLP----QQLPaaEGMTVRELVAIGRYpwhGALGRFGAADREKVEEAISLV---GLKPLAHRLVDSLSGGERQRAWIAML 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 158 LLGKPELLILDEPCNGLDLFSRELLLEQINKLAQLpNHPTLLFVSHYTEEILPIFKNIMLLKQGEIFAQGTRDKILTENV 237
Cdd:PRK10575 162 VAQDSRCLLLDEPTSALDIAHQVDVLALVHRLSQE-RGLTVIAVLHDINMAARYCDYLVALRGGEMIAQGTPAELMRGET 240
|
250
....*....|...
gi 915796356 238 LSKFYPKPIKIFP 250
Cdd:PRK10575 241 LEQIYGIPMGILP 253
|
|
| artP |
PRK11124 |
arginine transporter ATP-binding subunit; Provisional |
20-230 |
1.82e-14 |
|
arginine transporter ATP-binding subunit; Provisional
Pssm-ID: 182980 [Multi-domain] Cd Length: 242 Bit Score: 70.81 E-value: 1.82e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 20 ILKNINWSLHSGENWVLMGLNGAGKTTLLSLIYGNHWATTGSIEVLGETF------GKTNVLALKKRIGLIstavqsqFP 93
Cdd:PRK11124 17 ALFDITLDCPQGETLVLLGPSGAGKSSLLRVLNLLEMPRSGTLNIAGNHFdfsktpSDKAIRELRRNVGMV-------FQ 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 94 EHHLAQYIVLsgkfgtigIHNDFE----------KNDLNEAIGLLKKLGGDELVNKPYRVLSQGQRQLVLIARALLGKPE 163
Cdd:PRK11124 90 QYNLWPHLTV--------QQNLIEapcrvlglskDQALARAEKLLERLRLKPYADRFPLHLSGGQQQRVAIARALMMEPQ 161
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 915796356 164 LLILDEPCNGLDLFSRELLLEQINKLAQlpNHPTLLFVSHYTEEILPIFKNIMLLKQGEIFAQGTRD 230
Cdd:PRK11124 162 VLLFDEPTAALDPEITAQIVSIIRELAE--TGITQVIVTHEVEVARKTASRVVYMENGHIVEQGDAS 226
|
|
| ABC_FeS_Assembly |
cd03217 |
ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Biosynthesis of ... |
7-230 |
1.97e-14 |
|
ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Biosynthesis of iron-sulfur clusters (Fe-S) depends on multi-protein systems. The SUF system of E. coli and Erwinia chrysanthemi is important for Fe-S biogenesis under stressful conditions. The SUF system is made of six proteins: SufC is an atypical cytoplasmic ABC-ATPase, which forms a complex with SufB and SufD; SufA plays the role of a scaffold protein for assembly of iron-sulfur clusters and delivery to target proteins; SufS is a cysteine desulfurase which mobilizes the sulfur atom from cysteine and provides it to the cluster; SufE has no associated function yet.
Pssm-ID: 213184 [Multi-domain] Cd Length: 200 Bit Score: 69.86 E-value: 1.97e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 7 LSMKNVSFER-DKIILKNINWSLHSGENWVLMGLNGAGKTTLLSLIYGNHW--ATTGSIevlgeTFGKTNVLAL------ 77
Cdd:cd03217 1 LEIKDLHVSVgGKEILKGVNLTIKKGEVHALMGPNGSGKSTLAKTIMGHPKyeVTEGEI-----LFKGEDITDLppeera 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 78 KKRIGListAVQS--QFPEHHLAQYIvlsgkfgtigihndfekNDLNEAigllkklggdelvnkpyrvLSQGQRQLVLIA 155
Cdd:cd03217 76 RLGIFL---AFQYppEIPGVKNADFL-----------------RYVNEG-------------------FSGGEKKRNEIL 116
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 915796356 156 RALLGKPELLILDEPCNGLDLFSRELLLEQINKLAQLPNhpTLLFVSHYtEEIL----PIFKNIMLlkQGEIFAQGTRD 230
Cdd:cd03217 117 QLLLLEPDLAILDEPDSGLDIDALRLVAEVINKLREEGK--SVLIITHY-QRLLdyikPDRVHVLY--DGRIVKSGDKE 190
|
|
| cbiO |
PRK13648 |
cobalt transporter ATP-binding subunit; Provisional |
1-248 |
2.01e-14 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 184207 [Multi-domain] Cd Length: 269 Bit Score: 70.94 E-value: 2.01e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 1 MTNNAVLSMKNVSFERDK---IILKNINWSLHSGENWVLMGLNGAGKTTLLSLIYGNHWATTGSIEVLGETFGKTNVLAL 77
Cdd:PRK13648 2 EDKNSIIVFKNVSFQYQSdasFTLKDVSFNIPKGQWTSIVGHNGSGKSTIAKLMIGIEKVKSGEIFYNNQAITDDNFEKL 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 78 KKRIGLIStavqsQFPEHHLAQYIVlsgKFGT-IGIHN-----DFEKNDLNEAiglLKKLGGDELVNKPYRVLSQGQRQL 151
Cdd:PRK13648 82 RKHIGIVF-----QNPDNQFVGSIV---KYDVaFGLENhavpyDEMHRRVSEA---LKQVDMLERADYEPNALSGGQKQR 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 152 VLIARALLGKPELLILDEPCNGLDLFSRELLLEQINKLAQlPNHPTLLFVSHYTEEILPIfKNIMLLKQGEIFAQGTRDK 231
Cdd:PRK13648 151 VAIAGVLALNPSVIILDEATSMLDPDARQNLLDLVRKVKS-EHNITIISITHDLSEAMEA-DHVIVMNKGTVYKEGTPTE 228
|
250 260
....*....|....*....|...
gi 915796356 232 I------LTENVLSkfYPKPIKI 248
Cdd:PRK13648 229 IfdhaeeLTRIGLD--LPFPIKI 249
|
|
| PRK09984 |
PRK09984 |
phosphonate ABC transporter ATP-binding protein; |
21-228 |
2.23e-14 |
|
phosphonate ABC transporter ATP-binding protein;
Pssm-ID: 182182 [Multi-domain] Cd Length: 262 Bit Score: 70.81 E-value: 2.23e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 21 LKNINWSLHSGENWVLMGLNGAGKTTLL----SLIYGNhwATTGS-IEVLGETFGKTNVLALKKRIGLISTAVQsqFPEH 95
Cdd:PRK09984 20 LHAVDLNIHHGEMVALLGPSGSGKSTLLrhlsGLITGD--KSAGShIELLGRTVQREGRLARDIRKSRANTGYI--FQQF 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 96 HLAQYI-----VLSGKFGTIGIHND----FEKNDLNEAIGLLKKLGGDELVNKPYRVLSQGQRQLVLIARALLGKPELLI 166
Cdd:PRK09984 96 NLVNRLsvlenVLIGALGSTPFWRTcfswFTREQKQRALQALTRVGMVHFAHQRVSTLSGGQQQRVAIARALMQQAKVIL 175
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 915796356 167 LDEPCNGLDLFSRELLLEQINKLAQlPNHPTLLFVSHYTEEILPIFKNIMLLKQGEIFAQGT 228
Cdd:PRK09984 176 ADEPIASLDPESARIVMDTLRDINQ-NDGITVVVTLHQVDYALRYCERIVALRQGHVFYDGS 236
|
|
| 3a01208 |
TIGR00958 |
Conjugate Transporter-2 (CT2) Family protein; [Transport and binding proteins, Other] |
4-235 |
2.49e-14 |
|
Conjugate Transporter-2 (CT2) Family protein; [Transport and binding proteins, Other]
Pssm-ID: 273363 [Multi-domain] Cd Length: 711 Bit Score: 72.45 E-value: 2.49e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 4 NAVLSMKNVSF----ERDKIILKNINWSLHSGENWVLMGLNGAGKTTLLSLIYGNHWATTGSIEVLGETFGKTNVLALKK 79
Cdd:TIGR00958 476 EGLIEFQDVSFsypnRPDVPVLKGLTFTLHPGEVVALVGPSGSGKSTVAALLQNLYQPTGGQVLLDGVPLVQYDHHYLHR 555
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 80 RIGLIstavqsqfpehhlAQYIVLSGKFGTIGIHNDFEKNDLNEAIGLLKKLGGDELVNK---PYRV--------LSQGQ 148
Cdd:TIGR00958 556 QVALV-------------GQEPVLFSGSVRENIAYGLTDTPDEEIMAAAKAANAHDFIMEfpnGYDTevgekgsqLSGGQ 622
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 149 RQLVLIARALLGKPELLILDEPCNGLDLFSrELLLEQINKLAQLpnhpTLLFVSHYteeiLPIFKN---IMLLKQGEIFA 225
Cdd:TIGR00958 623 KQRIAIARALVRKPRVLILDEATSALDAEC-EQLLQESRSRASR----TVLLIAHR----LSTVERadqILVLKKGSVVE 693
|
250
....*....|
gi 915796356 226 QGTRDKILTE 235
Cdd:TIGR00958 694 MGTHKQLMED 703
|
|
| PRK11000 |
PRK11000 |
maltose/maltodextrin ABC transporter ATP-binding protein MalK; |
5-256 |
3.09e-14 |
|
maltose/maltodextrin ABC transporter ATP-binding protein MalK;
Pssm-ID: 182893 [Multi-domain] Cd Length: 369 Bit Score: 71.60 E-value: 3.09e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 5 AVLSMKNV--SFErDKIILKNINWSLHSGENWVLMGLNGAGKTTLLSLIYGNHWATTGSIEVLGEtfgKTNVLALKKR-I 81
Cdd:PRK11000 2 ASVTLRNVtkAYG-DVVISKDINLDIHEGEFVVFVGPSGCGKSTLLRMIAGLEDITSGDLFIGEK---RMNDVPPAERgV 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 82 GLIstaVQSQFPEHHLAQYIVLSgkFGT--IGIHNDFEKNDLNEAIGLLKKlggDELVNKPYRVLSQGQRQLVLIARALL 159
Cdd:PRK11000 78 GMV---FQSYALYPHLSVAENMS--FGLklAGAKKEEINQRVNQVAEVLQL---AHLLDRKPKALSGGQRQRVAIGRTLV 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 160 GKPELLILDEPCNGLDLFSRELLLEQINKLAQLPNHpTLLFVSHYTEEILPIFKNIMLLKQGEIFAQGtrdkiltenvls 239
Cdd:PRK11000 150 AEPSVFLLDEPLSNLDAALRVQMRIEISRLHKRLGR-TMIYVTHDQVEAMTLADKIVVLDAGRVAQVG------------ 216
|
250
....*....|....*..
gi 915796356 240 kfypKPIKIFPVTNNRF 256
Cdd:PRK11000 217 ----KPLELYHYPANRF 229
|
|
| PRK09700 |
PRK09700 |
D-allose ABC transporter ATP-binding protein AlsA; |
21-221 |
3.88e-14 |
|
D-allose ABC transporter ATP-binding protein AlsA;
Pssm-ID: 182036 [Multi-domain] Cd Length: 510 Bit Score: 71.74 E-value: 3.88e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 21 LKNINWSLHSGENWVLMGLNGAGKTTLLSLIYGNHWATTGSIEVLGETFGK-TNVLALKKRIGLIS---------TAVQS 90
Cdd:PRK09700 21 LKSVNLTVYPGEIHALLGENGAGKSTLMKVLSGIHEPTKGTITINNINYNKlDHKLAAQLGIGIIYqelsvidelTVLEN 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 91 QFPEHHLAQyivlsgKFGTIGIhNDFEKNDLNEAIGLLK---KLGGDELVNKpyrvLSQGQRQLVLIARALLGKPELLIL 167
Cdd:PRK09700 101 LYIGRHLTK------KVCGVNI-IDWREMRVRAAMMLLRvglKVDLDEKVAN----LSISHKQMLEIAKTLMLDAKVIIM 169
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 915796356 168 DEPCNGLDLFSRELLLEQINKLAQlpNHPTLLFVSHYTEEILPIFKNIMLLKQG 221
Cdd:PRK09700 170 DEPTSSLTNKEVDYLFLIMNQLRK--EGTAIVYISHKLAEIRRICDRYTVMKDG 221
|
|
| PRK14258 |
PRK14258 |
phosphate ABC transporter ATP-binding protein; Provisional |
7-240 |
3.99e-14 |
|
phosphate ABC transporter ATP-binding protein; Provisional
Pssm-ID: 184593 [Multi-domain] Cd Length: 261 Bit Score: 70.07 E-value: 3.99e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 7 LSMKNVSFERD-KIILKNINWSLHSGENWVLMGLNGAGKTTLL-SLIYGNHWATTGSIEVLGETFGKtNVLALKKRIGLI 84
Cdd:PRK14258 8 IKVNNLSFYYDtQKILEGVSMEIYQSKVTAIIGPSGCGKSTFLkCLNRMNELESEVRVEGRVEFFNQ-NIYERRVNLNRL 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 85 STAVQSQFPEHHLAQYIVLSG-KFGT--IGIHNDFEKNDLNEAIGLLKKLGgDELVNKPYRV---LSQGQRQLVLIARAL 158
Cdd:PRK14258 87 RRQVSMVHPKPNLFPMSVYDNvAYGVkiVGWRPKLEIDDIVESALKDADLW-DEIKHKIHKSaldLSGGQQQRLCIARAL 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 159 LGKPELLILDEPCNGLDLFSrELLLEQINKLAQLPNHPTLLFVSHYTEEILPIFKNIMLLKQ-----GEIFAQGTRDKIL 233
Cdd:PRK14258 166 AVKPKVLLMDEPCFGLDPIA-SMKVESLIQSLRLRSELTMVIVSHNLHQVSRLSDFTAFFKGnenriGQLVEFGLTKKIF 244
|
....*..
gi 915796356 234 TENVLSK 240
Cdd:PRK14258 245 NSPHDSR 251
|
|
| PRK15056 |
PRK15056 |
manganese/iron ABC transporter ATP-binding protein; |
1-241 |
5.43e-14 |
|
manganese/iron ABC transporter ATP-binding protein;
Pssm-ID: 185016 [Multi-domain] Cd Length: 272 Bit Score: 69.91 E-value: 5.43e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 1 MTNNAVLSMKNVSFERDKIILKNINWSLHSGENWVLMGLNGAGKTTLLSLIYGNHWATTGSIEVLGETFGKtnvlALKKr 80
Cdd:PRK15056 3 QQAGIVVNDVTVTWRNGHTALRDASFTVPGGSIAALVGVNGSGKSTLFKALMGFVRLASGKISILGQPTRQ----ALQK- 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 81 iGLISTAVQSQ-----FPEhhLAQYIVLSGKFGTIGIHNDFEKNDLNEAIGLLKKLGGDELVNKPYRVLSQGQRQLVLIA 155
Cdd:PRK15056 78 -NLVAYVPQSEevdwsFPV--LVEDVVMMGRYGHMGWLRRAKKRDRQIVTAALARVDMVEFRHRQIGELSGGQKKRVFLA 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 156 RALLGKPELLILDEPCNGLDLFSRELLleqINKLAQLPNHPTLLFVSHYTEEILPIFKNIMLLKQGEIFAQG-TRDKILT 234
Cdd:PRK15056 155 RAIAQQGQVILLDEPFTGVDVKTEARI---ISLLRELRDEGKTMLVSTHNLGSVTEFCDYTVMVKGTVLASGpTETTFTA 231
|
....*..
gi 915796356 235 ENVLSKF 241
Cdd:PRK15056 232 ENLELAF 238
|
|
| PRK10535 |
PRK10535 |
macrolide ABC transporter ATP-binding protein/permease MacB; |
4-225 |
6.49e-14 |
|
macrolide ABC transporter ATP-binding protein/permease MacB;
Pssm-ID: 182528 [Multi-domain] Cd Length: 648 Bit Score: 70.91 E-value: 6.49e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 4 NAVLSMKNV-----SFERDKIILKNINWSLHSGENWVLMGLNGAGKTTLLSLIYGNHWATTGSIEVLGETFGKTNVLAL- 77
Cdd:PRK10535 2 TALLELKDIrrsypSGEEQVEVLKGISLDIYAGEMVAIVGASGSGKSTLMNILGCLDKPTSGTYRVAGQDVATLDADALa 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 78 ---KKRIGLIstavqsqFPEHHLAQYIVLSGKFGTIGIHNDFEKND-LNEAIGLLKKLGGDELVNKPYRVLSQGQRQLVL 153
Cdd:PRK10535 82 qlrREHFGFI-------FQRYHLLSHLTAAQNVEVPAVYAGLERKQrLLRAQELLQRLGLEDRVEYQPSQLSGGQQQRVS 154
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 915796356 154 IARALLGKPELLILDEPCNGLDLFSRElllEQINKLAQLPN--HpTLLFVSHyTEEILPIFKNIMLLKQGEIFA 225
Cdd:PRK10535 155 IARALMNGGQVILADEPTGALDSHSGE---EVMAILHQLRDrgH-TVIIVTH-DPQVAAQAERVIEIRDGEIVR 223
|
|
| ABC_YhbG |
cd03218 |
ATP-binding cassette component of YhbG transport system; The ABC transporters belonging to the ... |
16-242 |
9.64e-14 |
|
ATP-binding cassette component of YhbG transport system; The ABC transporters belonging to the YhbG family are similar to members of the Mj1267_LivG family, which is involved in the transport of branched-chain amino acids. The genes yhbG and yhbN are located in a single operon and may function together in cell envelope during biogenesis. YhbG is the putative ATP-binding cassette component and YhbN is the putative periplasmic-binding protein. Depletion of each gene product leads to growth arrest, irreversible cell damage and loss of viability in E. coli. The YhbG homolog (NtrA) is essential in Rhizobium meliloti, a symbiotic nitrogen-fixing bacterium.
Pssm-ID: 213185 [Multi-domain] Cd Length: 232 Bit Score: 68.72 E-value: 9.64e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 16 RDKIILKNINWSLHSGENWVLMGLNGAGKTTLLSLIYGNHWATTGSIEVLGETFGKtnvLALKKRIGL-ISTAVQ--SQF 92
Cdd:cd03218 11 GKRKVVNGVSLSVKQGEIVGLLGPNGAGKTTTFYMIVGLVKPDSGKILLDGQDITK---LPMHKRARLgIGYLPQeaSIF 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 93 PEHHLAQYIVLsgkfgTIGIHNDFEKNDLNEAIGLLKKLGGDELVNKPYRVLSQGQRQLVLIARALLGKPELLILDEPCN 172
Cdd:cd03218 88 RKLTVEENILA-----VLEIRGLSKKEREEKLEELLEEFHITHLRKSKASSLSGGERRRVEIARALATNPKFLLLDEPFA 162
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 173 GLDLFSRELLLEQINKLAQlpNHPTLLFVSHYTEEILPIFKNIMLLKQGEIFAQGTRDKILTENVLSKFY 242
Cdd:cd03218 163 GVDPIAVQDIQKIIKILKD--RGIGVLITDHNVRETLSITDRAYIIYEGKVLAEGTPEEIAANELVRKVY 230
|
|
| PRK10790 |
PRK10790 |
SmdB family multidrug efflux ABC transporter permease/ATP-binding protein; |
7-233 |
1.14e-13 |
|
SmdB family multidrug efflux ABC transporter permease/ATP-binding protein;
Pssm-ID: 182733 [Multi-domain] Cd Length: 592 Bit Score: 70.13 E-value: 1.14e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 7 LSMKNVSF--ERDKIILKNINWSLHSGENWVLMGLNGAGKTTLLSLIYGNHWATTGSIEVLGETFGKTNVLALKKRIGLi 84
Cdd:PRK10790 341 IDIDNVSFayRDDNLVLQNINLSVPSRGFVALVGHTGSGKSTLASLLMGYYPLTEGEIRLDGRPLSSLSHSVLRQGVAM- 419
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 85 staVQsQFPehhlaqyIVLSGKFG---TIGIHND-------FEKNDLNEAI-----GLLKKLGgdELVNKpyrvLSQGQR 149
Cdd:PRK10790 420 ---VQ-QDP-------VVLADTFLanvTLGRDISeeqvwqaLETVQLAELArslpdGLYTPLG--EQGNN----LSVGQK 482
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 150 QLVLIARALLGKPELLILDEPCNGLDLFSrelllEQ-INK-LAQLPNHPTLLFVSHYTEEILPIfKNIMLLKQGEIFAQG 227
Cdd:PRK10790 483 QLLALARVLVQTPQILILDEATANIDSGT-----EQaIQQaLAAVREHTTLVVIAHRLSTIVEA-DTILVLHRGQAVEQG 556
|
....*.
gi 915796356 228 TRDKIL 233
Cdd:PRK10790 557 THQQLL 562
|
|
| YbbA |
COG4181 |
Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase ... |
20-203 |
1.20e-13 |
|
Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component [Secondary metabolites biosynthesis, transport and catabolism];
Pssm-ID: 443338 [Multi-domain] Cd Length: 233 Bit Score: 68.23 E-value: 1.20e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 20 ILKNINWSLHSGENWVLMGLNGAGKTTLLSLIYGNHWATTGSIEVLGETFGKTN---VLALK-KRIG-------LIS--T 86
Cdd:COG4181 27 ILKGISLEVEAGESVAIVGASGSGKSTLLGLLAGLDRPTSGTVRLAGQDLFALDedaRARLRaRHVGfvfqsfqLLPtlT 106
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 87 AVQS-QFP-EhhLAqyivlsgkfgtiGIHNDFEKndlneAIGLLKKLG-GDELVNKPyRVLSQGQRQLVLIARALLGKPE 163
Cdd:COG4181 107 ALENvMLPlE--LA------------GRRDARAR-----ARALLERVGlGHRLDHYP-AQLSGGEQQRVALARAFATEPA 166
|
170 180 190 200
....*....|....*....|....*....|....*....|...
gi 915796356 164 LLILDEPCNGLDLFSREL---LLEQINKLAqlpnHPTLLFVSH 203
Cdd:COG4181 167 ILFADEPTGNLDAATGEQiidLLFELNRER----GTTLVLVTH 205
|
|
| livF |
PRK11614 |
high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivF; |
4-242 |
1.27e-13 |
|
high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivF;
Pssm-ID: 183231 [Multi-domain] Cd Length: 237 Bit Score: 68.37 E-value: 1.27e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 4 NAVLSMKNVSFERDKI-ILKNINWSLHSGENWVLMGLNGAGKTTLLSLIYGNHWATTGSIEVLGETFGKTNVLALKKRIG 82
Cdd:PRK11614 3 KVMLSFDKVSAHYGKIqALHEVSLHINQGEIVTLIGANGAGKTTLLGTLCGDPRATSGRIVFDGKDITDWQTAKIMREAV 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 83 LISTAVQSQFPEHHLAQYIVLSGKFGtigihndfEKNDLNEAIGLLKKLGGDELVNKPYR--VLSQGQRQLVLIARALLG 160
Cdd:PRK11614 83 AIVPEGRRVFSRMTVEENLAMGGFFA--------ERDQFQERIKWVYELFPRLHERRIQRagTMSGGEQQMLAIGRALMS 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 161 KPELLILDEPCNGLdlfsRELLLEQI-NKLAQLPNHP-TLLFVSHYTEEILPIFKNIMLLKQGEIFAQGTRDKILTENVL 238
Cdd:PRK11614 155 QPRLLLLDEPSLGL----APIIIQQIfDTIEQLREQGmTIFLVEQNANQALKLADRGYVLENGHVVLEDTGDALLANEAV 230
|
....
gi 915796356 239 SKFY 242
Cdd:PRK11614 231 RSAY 234
|
|
| PhnL |
COG4778 |
Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnL [Inorganic ion ... |
4-189 |
1.29e-13 |
|
Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnL [Inorganic ion transport and metabolism];
Pssm-ID: 443809 [Multi-domain] Cd Length: 229 Bit Score: 68.23 E-value: 1.29e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 4 NAVLSMKNVS--F---ERDKIIL---KNINWSLHSGENWVLMGLNGAGKTTLLSLIYGNHWATTGSIEVLGEtFGKTN-- 73
Cdd:COG4778 2 TTLLEVENLSktFtlhLQGGKRLpvlDGVSFSVAAGECVALTGPSGAGKSTLLKCIYGNYLPDSGSILVRHD-GGWVDla 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 74 ------VLALKKR-IGLIstavqSQF----P----EHHLAQYIVLSGkfgtigihndFEKND-LNEAIGLLKKLGGDE-L 136
Cdd:COG4778 81 qaspreILALRRRtIGYV-----SQFlrviPrvsaLDVVAEPLLERG----------VDREEaRARARELLARLNLPErL 145
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 915796356 137 VNKPYRVLSQGQRQLVLIARALLGKPELLILDEPCNGLDLFSRELLLEQINKL 189
Cdd:COG4778 146 WDLPPATFSGGEQQRVNIARGFIADPPLLLLDEPTASLDAANRAVVVELIEEA 198
|
|
| urea_trans_UrtE |
TIGR03410 |
urea ABC transporter, ATP-binding protein UrtE; Members of this protein family are ABC ... |
20-173 |
1.33e-13 |
|
urea ABC transporter, ATP-binding protein UrtE; Members of this protein family are ABC transporter ATP-binding subunits associated with urea transport and metabolism. This protein is found in a conserved five-gene transport operon typically found adjacent to urease genes. It was shown in Cyanobacteria that disruption leads to the loss of high-affinity urea transport activity. [Transport and binding proteins, Amino acids, peptides and amines]
Pssm-ID: 274567 [Multi-domain] Cd Length: 230 Bit Score: 67.94 E-value: 1.33e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 20 ILKNINWSLHSGENWVLMGLNGAGKTTLLSLIYGNHWATTGSIEVLGETFGKTNVLALKKR------------------- 80
Cdd:TIGR03410 15 ILRGVSLEVPKGEVTCVLGRNGVGKTTLLKTLMGLLPVKSGSIRLDGEDITKLPPHERARAgiayvpqgreifprltvee 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 81 ---IGLISTAVQSQF-PEHHLAQYIVLsgkfgtigihndFEkndlneaigLLKKLGGDelvnkpyrvLSQGQRQLVLIAR 156
Cdd:TIGR03410 95 nllTGLAALPRRSRKiPDEIYELFPVL------------KE---------MLGRRGGD---------LSGGQQQQLAIAR 144
|
170
....*....|....*..
gi 915796356 157 ALLGKPELLILDEPCNG 173
Cdd:TIGR03410 145 ALVTRPKLLLLDEPTEG 161
|
|
| glnQ |
PRK09493 |
glutamine ABC transporter ATP-binding protein GlnQ; |
10-203 |
1.51e-13 |
|
glutamine ABC transporter ATP-binding protein GlnQ;
Pssm-ID: 181906 [Multi-domain] Cd Length: 240 Bit Score: 68.20 E-value: 1.51e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 10 KNVS--FErDKIILKNINWSLHSGENWVLMGLNGAGKTTLLSLIYGNHWATTGSIEVLGETF--GKTNVLALKKRIGLis 85
Cdd:PRK09493 5 KNVSkhFG-PTQVLHNIDLNIDQGEVVVIIGPSGSGKSTLLRCINKLEEITSGDLIVDGLKVndPKVDERLIRQEAGM-- 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 86 taVQSQFpeHHLAQYIVLSG-KFGTIGIHNDFEKNDLNEAIGLLKKLGGDELVNKPYRVLSQGQRQLVLIARALLGKPEL 164
Cdd:PRK09493 82 --VFQQF--YLFPHLTALENvMFGPLRVRGASKEEAEKQARELLAKVGLAERAHHYPSELSGGQQQRVAIARALAVKPKL 157
|
170 180 190
....*....|....*....|....*....|....*....
gi 915796356 165 LILDEPCNGLDLFSRELLLEQINKLAQlpNHPTLLFVSH 203
Cdd:PRK09493 158 MLFDEPTSALDPELRHEVLKVMQDLAE--EGMTMVIVTH 194
|
|
| PRK13538 |
PRK13538 |
cytochrome c biogenesis heme-transporting ATPase CcmA; |
6-175 |
1.59e-13 |
|
cytochrome c biogenesis heme-transporting ATPase CcmA;
Pssm-ID: 184125 [Multi-domain] Cd Length: 204 Bit Score: 67.52 E-value: 1.59e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 6 VLSMKNVSFERD-KIILKNINWSLHSGENWVLMGLNGAGKTTLLSLIYGNHWATTGSIEVLGETFGK------TNVLALK 78
Cdd:PRK13538 1 MLEARNLACERDeRILFSGLSFTLNAGELVQIEGPNGAGKTSLLRILAGLARPDAGEVLWQGEPIRRqrdeyhQDLLYLG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 79 KRIGLIS--TAvqsqfpEHHLAQYIVLSGKFgtigihNDFEKNDLNEAIGllkkLGGDELVnkPYRVLSQGQRQLVLIAR 156
Cdd:PRK13538 81 HQPGIKTelTA------LENLRFYQRLHGPG------DDEALWEALAQVG----LAGFEDV--PVRQLSAGQQRRVALAR 142
|
170
....*....|....*....
gi 915796356 157 ALLGKPELLILDEPCNGLD 175
Cdd:PRK13538 143 LWLTRAPLWILDEPFTAID 161
|
|
| PRK13549 |
PRK13549 |
xylose transporter ATP-binding subunit; Provisional |
6-244 |
2.21e-13 |
|
xylose transporter ATP-binding subunit; Provisional
Pssm-ID: 184134 [Multi-domain] Cd Length: 506 Bit Score: 69.19 E-value: 2.21e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 6 VLSMKNVSFERDKII-LKNINWSLHSGENWVLMGLNGAGKTTL---LSLIYgNHWATTGSIEVLGETFGKTNVL-ALKKR 80
Cdd:PRK13549 5 LLEMKNITKTFGGVKaLDNVSLKVRAGEIVSLCGENGAGKSTLmkvLSGVY-PHGTYEGEIIFEGEELQASNIRdTERAG 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 81 IGLIS---TAVqsqfPEHHLAQYIVLSGKFGTIGIHNDFEKNdlNEAIGLLKKLGGDELVNKPYRVLSQGQRQLVLIARA 157
Cdd:PRK13549 84 IAIIHqelALV----KELSVLENIFLGNEITPGGIMDYDAMY--LRAQKLLAQLKLDINPATPVGNLGLGQQQLVEIAKA 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 158 LLGKPELLILDEPCNGLDLFSRELLLEQINklaQLPNHP-TLLFVSHYTEEILPIFKNIMLLKQGEIF-----AQGTRDK 231
Cdd:PRK13549 158 LNKQARLLILDEPTASLTESETAVLLDIIR---DLKAHGiACIYISHKLNEVKAISDTICVIRDGRHIgtrpaAGMTEDD 234
|
250
....*....|....*.
gi 915796356 232 ILTENV---LSKFYPK 244
Cdd:PRK13549 235 IITMMVgreLTALYPR 250
|
|
| potG |
PRK11607 |
putrescine ABC transporter ATP-binding subunit PotG; |
23-232 |
2.32e-13 |
|
putrescine ABC transporter ATP-binding subunit PotG;
Pssm-ID: 183226 [Multi-domain] Cd Length: 377 Bit Score: 69.09 E-value: 2.32e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 23 NINWSLHSGENWVLMGLNGAGKTTLLSLIYGNHWATTGSIEVLGETFgkTNVLALKKRIGLIstaVQSQ--FPEHHLAQY 100
Cdd:PRK11607 37 DVSLTIYKGEIFALLGASGCGKSTLLRMLAGFEQPTAGQIMLDGVDL--SHVPPYQRPINMM---FQSYalFPHMTVEQN 111
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 101 IVLsgkfgtiGIHND-FEKNDLNEAIG-LLKKLGGDELVNKPYRVLSQGQRQLVLIARALLGKPELLILDEPCNGLDLFS 178
Cdd:PRK11607 112 IAF-------GLKQDkLPKAEIASRVNeMLGLVHMQEFAKRKPHQLSGGQRQRVALARSLAKRPKLLLLDEPMGALDKKL 184
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 915796356 179 RE-LLLEQINKLAQLpnHPTLLFVSHYTEEILPIFKNIMLLKQGEIFAQGTRDKI 232
Cdd:PRK11607 185 RDrMQLEVVDILERV--GVTCVMVTHDQEEAMTMAGRIAIMNRGKFVQIGEPEEI 237
|
|
| MalK |
COG3839 |
ABC-type sugar transport system, ATPase component MalK [Carbohydrate transport and metabolism]; ... |
5-228 |
2.55e-13 |
|
ABC-type sugar transport system, ATPase component MalK [Carbohydrate transport and metabolism];
Pssm-ID: 443050 [Multi-domain] Cd Length: 352 Bit Score: 68.56 E-value: 2.55e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 5 AVLSMKNVSFERDKI-ILKNINWSLHSGENWVLMGLNGAGKTTLLSLIYGNHWATTGSIEvlgetFGKTNVLAL--KKR- 80
Cdd:COG3839 2 ASLELENVSKSYGGVeALKDIDLDIEDGEFLVLLGPSGCGKSTLLRMIAGLEDPTSGEIL-----IGGRDVTDLppKDRn 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 81 IGLI--STAVqsqFPehHL------AQYIVLSGkfgtigihndFEKNDLNEAIG-LLKKLGGDELVN-KPyRVLSQGQRQ 150
Cdd:COG3839 77 IAMVfqSYAL---YP--HMtvyeniAFPLKLRK----------VPKAEIDRRVReAAELLGLEDLLDrKP-KQLSGGQRQ 140
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 915796356 151 LVLIARALLGKPELLILDEPCNGLDLFSRELLLEQINKL-AQLPNhpTLLFVSHYTEEILPIFKNIMLLKQGEIFAQGT 228
Cdd:COG3839 141 RVALGRALVREPKVFLLDEPLSNLDAKLRVEMRAEIKRLhRRLGT--TTIYVTHDQVEAMTLADRIAVMNDGRIQQVGT 217
|
|
| PRK10908 |
PRK10908 |
cell division ATP-binding protein FtsE; |
21-223 |
2.79e-13 |
|
cell division ATP-binding protein FtsE;
Pssm-ID: 182829 [Multi-domain] Cd Length: 222 Bit Score: 67.21 E-value: 2.79e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 21 LKNINWSLHSGENWVLMGLNGAGKTTLLSLIYGNHWATTGSIEVLGETFGK---TNVLALKKRIGLIstavqsqFPEHHL 97
Cdd:PRK10908 18 LQGVTFHMRPGEMAFLTGHSGAGKSTLLKLICGIERPSAGKIWFSGHDITRlknREVPFLRRQIGMI-------FQDHHL 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 98 ----------AQYIVLSGKFGtigihNDFEK--NDLNEAIGLLkklggDELVNKPYRvLSQGQRQLVLIARALLGKPELL 165
Cdd:PRK10908 91 lmdrtvydnvAIPLIIAGASG-----DDIRRrvSAALDKVGLL-----DKAKNFPIQ-LSGGEQQRVGIARAVVNKPAVL 159
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 166 ILDEPCNGLDlfsrELLLEQINKLAQLPNH--PTLLFVSHYTEEILPIFKNIMLLKQGEI 223
Cdd:PRK10908 160 LADEPTGNLD----DALSEGILRLFEEFNRvgVTVLMATHDIGLISRRSYRMLTLSDGHL 215
|
|
| rim_protein |
TIGR01257 |
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim ... |
24-228 |
3.20e-13 |
|
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim protein) in eukaryotes. It is the member of ABC transporter superfamily. Rim protein is a membrane glycoprotein which is localized in the photoreceptor outer segment discs. Mutation/s in its genetic loci is implicated in the recessive Stargardt's disease. [Transport and binding proteins, Other]
Pssm-ID: 130324 [Multi-domain] Cd Length: 2272 Bit Score: 69.27 E-value: 3.20e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 24 INWSLHSGENWVLMGLNGAGKTTLLSLIYGNHWATTGSIEVLGETFgKTNVLALKKRIGLIStavQSQFPEHHL--AQYI 101
Cdd:TIGR01257 949 LNITFYENQITAFLGHNGAGKTTTLSILTGLLPPTSGTVLVGGKDI-ETNLDAVRQSLGMCP---QHNILFHHLtvAEHI 1024
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 102 VLSGKF-GTIGIHNDFEKNDLNEAIGLLKKLggdelvNKPYRVLSQGQRQLVLIARALLGKPELLILDEPCNGLDLFSRE 180
Cdd:TIGR01257 1025 LFYAQLkGRSWEEAQLEMEAMLEDTGLHHKR------NEEAQDLSGGMQRKLSVAIAFVGDAKVVVLDEPTSGVDPYSRR 1098
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 915796356 181 LLLEQinkLAQLPNHPTLLFVSHYTEEILPIFKNIMLLKQGEIFAQGT 228
Cdd:TIGR01257 1099 SIWDL---LLKYRSGRTIIMSTHHMDEADLLGDRIAIISQGRLYCSGT 1143
|
|
| PRK10762 |
PRK10762 |
D-ribose transporter ATP binding protein; Provisional |
21-233 |
3.27e-13 |
|
D-ribose transporter ATP binding protein; Provisional
Pssm-ID: 236755 [Multi-domain] Cd Length: 501 Bit Score: 68.88 E-value: 3.27e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 21 LKNINWSLHSGENWVLMGLNGAGKTTLLSLIYGNHWATTGSIEVLGETF-------GKTNVLAL----KKRIGLI-STAV 88
Cdd:PRK10762 268 VNDVSFTLRKGEILGVSGLMGAGRTELMKVLYGALPRTSGYVTLDGHEVvtrspqdGLANGIVYisedRKRDGLVlGMSV 347
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 89 QSQFPEHHLAQYIVLSGKfgtigIHNDFEKNDLNEAIGL--LKKLGGDELVNKpyrvLSQGQRQLVLIARALLGKPELLI 166
Cdd:PRK10762 348 KENMSLTALRYFSRAGGS-----LKHADEQQAVSDFIRLfnIKTPSMEQAIGL----LSGGNQQKVAIARGLMTRPKVLI 418
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 915796356 167 LDEPCNGLDLFSRELLLEQINKLAQlpNHPTLLFVSHYTEEILPIFKNIMLLKQGEI---F--AQGTRDKIL 233
Cdd:PRK10762 419 LDEPTRGVDVGAKKEIYQLINQFKA--EGLSIILVSSEMPEVLGMSDRILVMHEGRIsgeFtrEQATQEKLM 488
|
|
| PRK15064 |
PRK15064 |
ABC transporter ATP-binding protein; Provisional |
1-203 |
3.38e-13 |
|
ABC transporter ATP-binding protein; Provisional
Pssm-ID: 237894 [Multi-domain] Cd Length: 530 Bit Score: 68.77 E-value: 3.38e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 1 MTNNAvLSMKNVSFERD-KIILKNINWSLHSGENWVLMGLNGAGKTTLLSLIYGNHWATTGSIEvlgetfgktnvLALKK 79
Cdd:PRK15064 315 LHRNA-LEVENLTKGFDnGPLFKNLNLLLEAGERLAIIGENGVGKTTLLRTLVGELEPDSGTVK-----------WSENA 382
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 80 RIGListavqsqFPEHHLAqyivlsgkfgtigihnDFEkNDLN--EAIGLLKKLGGDEL---------------VNKPYR 142
Cdd:PRK15064 383 NIGY--------YAQDHAY----------------DFE-NDLTlfDWMSQWRQEGDDEQavrgtlgrllfsqddIKKSVK 437
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 915796356 143 VLSQGQRQLVLIARALLGKPELLILDEPCNGLDLFSRELLleqinKLAqLPNHP-TLLFVSH 203
Cdd:PRK15064 438 VLSGGEKGRMLFGKLMMQKPNVLVMDEPTNHMDMESIESL-----NMA-LEKYEgTLIFVSH 493
|
|
| PstB |
COG1117 |
ABC-type phosphate transport system, ATPase component [Inorganic ion transport and metabolism]; ... |
2-175 |
3.74e-13 |
|
ABC-type phosphate transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 440734 [Multi-domain] Cd Length: 258 Bit Score: 67.37 E-value: 3.74e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 2 TNNAVLSMKNVSFE-RDKIILKNINWSLHSGENWVLMGLNGAGKTTLLS-------LIYGNHwaTTGSIEVLGE-TFGK- 71
Cdd:COG1117 7 TLEPKIEVRNLNVYyGDKQALKDINLDIPENKVTALIGPSGCGKSTLLRclnrmndLIPGAR--VEGEILLDGEdIYDPd 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 72 TNVLALKKRIGLIStavqsQ----FPehhlaqyivlsgkfGTI-----------GIHNdfeKNDLNEAI-GLLKKLG--- 132
Cdd:COG1117 85 VDVVELRRRVGMVF-----QkpnpFP--------------KSIydnvayglrlhGIKS---KSELDEIVeESLRKAAlwd 142
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
gi 915796356 133 --GDELvNKPYRVLSQGQRQLVLIARALLGKPELLILDEPCNGLD 175
Cdd:COG1117 143 evKDRL-KKSALGLSGGQQQRLCIARALAVEPEVLLMDEPTSALD 186
|
|
| CydC |
TIGR02868 |
thiol reductant ABC exporter, CydC subunit; The gene pair cydCD encodes an ABC-family ... |
12-203 |
4.27e-13 |
|
thiol reductant ABC exporter, CydC subunit; The gene pair cydCD encodes an ABC-family transporter in which each gene contains an N-terminal membrane-spanning domain (pfam00664) and a C-terminal ATP-binding domain (pfam00005). In E. coli these genes were discovered as mutants which caused the terminal heme-copper oxidase complex cytochrome bd to fail to assemble. Recent work has shown that the transporter is involved in export of redox-active thiol compounds such as cysteine and glutathione. The linkage to assembly of the cytochrome bd complex is further supported by the conserved operon structure found outside the gammaproteobacteria (cydABCD) containing both the transporter and oxidase genes components. The genes used as the seed members for this model are all either found in the gammproteobacterial context or the CydABCD context. All members of this family scoring above trusted at the time of its creation were from genomes which encode a cytochrome bd complex.
Pssm-ID: 274331 [Multi-domain] Cd Length: 530 Bit Score: 68.54 E-value: 4.27e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 12 VSFERDKIILKNINWSLHSGENWVLMGLNGAGKTTLLSLIYGNHWATTGSIEVLGETFGKTNVLALKKRIGListavqsq 91
Cdd:TIGR02868 342 AGYPGAPPVLDGVSLDLPPGERVAILGPSGSGKSTLLATLAGLLDPLQGEVTLDGVPVSSLDQDEVRRRVSV-------- 413
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 92 FPEH-HLaqyivlsgkFGTIGIHN---------DFEKNDLNEAIGLLKKL-----GGDELVNKPYRVLSQGQRQLVLIAR 156
Cdd:TIGR02868 414 CAQDaHL---------FDTTVRENlrlarpdatDEELWAALERVGLADWLralpdGLDTVLGEGGARLSGGERQRLALAR 484
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 915796356 157 ALLGKPELLILDEPCNGLDLFSRELLLEQInkLAQLPNHPTLLfVSH 203
Cdd:TIGR02868 485 ALLADAPILLLDEPTEHLDAETADELLEDL--LAALSGRTVVL-ITH 528
|
|
| 3a01204 |
TIGR00955 |
The Eye Pigment Precursor Transporter (EPP) Family protein; [Transport and binding proteins, ... |
18-228 |
6.22e-13 |
|
The Eye Pigment Precursor Transporter (EPP) Family protein; [Transport and binding proteins, Other]
Pssm-ID: 273361 [Multi-domain] Cd Length: 617 Bit Score: 68.15 E-value: 6.22e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 18 KIILKNINWSLHSGENWVLMGLNGAGKTTLLSLIYGNHWATT---GSIEVLGETFGKtnvlalkKRIGLISTAVQSQ--- 91
Cdd:TIGR00955 38 KHLLKNVSGVAKPGELLAVMGSSGAGKTTLMNALAFRSPKGVkgsGSVLLNGMPIDA-------KEMRAISAYVQQDdlf 110
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 92 FPEHHLAQYIVLSGKFGtigIHNDFEK-------NDLNEAIGLLKklGGDELVNKPYRV--LSQGQRQLVLIARALLGKP 162
Cdd:TIGR00955 111 IPTLTVREHLMFQAHLR---MPRRVTKkekrervDEVLQALGLRK--CANTRIGVPGRVkgLSGGERKRLAFASELLTDP 185
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 915796356 163 ELLILDEPCNGLDLFSRELLLEQINKLAQlpNHPTLLFVSHY-TEEILPIFKNIMLLKQGEIFAQGT 228
Cdd:TIGR00955 186 PLLFCDEPTSGLDSFMAYSVVQVLKGLAQ--KGKTIICTIHQpSSELFELFDKIILMAEGRVAYLGS 250
|
|
| nikE |
PRK10419 |
nickel ABC transporter ATP-binding protein NikE; |
18-223 |
9.75e-13 |
|
nickel ABC transporter ATP-binding protein NikE;
Pssm-ID: 236689 [Multi-domain] Cd Length: 268 Bit Score: 66.25 E-value: 9.75e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 18 KIILKNINWSLHSGENWVLMGLNGAGKTTLLSLIYGNHWATTGSIEVLGETFGKTN---VLALKKRIGLI----STAVQS 90
Cdd:PRK10419 25 QTVLNNVSLSLKSGETVALLGRSGCGKSTLARLLVGLESPSQGNVSWRGEPLAKLNraqRKAFRRDIQMVfqdsISAVNP 104
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 91 QF--------PEHHLAqyivlsgkfgtigihndfeknDLNEA------IGLLKKLG-GDELVNKPYRVLSQGQRQLVLIA 155
Cdd:PRK10419 105 RKtvreiirePLRHLL---------------------SLDKAerlaraSEMLRAVDlDDSVLDKRPPQLSGGQLQRVCLA 163
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 915796356 156 RALLGKPELLILDEPCNGLDLFSRELLLEQINKLAQlPNHPTLLFVSHYTEEILPIFKNIMLLKQGEI 223
Cdd:PRK10419 164 RALAVEPKLLILDEAVSNLDLVLQAGVIRLLKKLQQ-QFGTACLFITHDLRLVERFCQRVMVMDNGQI 230
|
|
| PRK15439 |
PRK15439 |
autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional |
6-238 |
1.02e-12 |
|
autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional
Pssm-ID: 185336 [Multi-domain] Cd Length: 510 Bit Score: 67.38 E-value: 1.02e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 6 VLSMKNVSFERdkiiLKNINWSLHSGENWVLMGLNGAGKTTLLSLIYGNHWATTGSIEVLGETFGKTNVLAlKKRIGLIS 85
Cdd:PRK15439 268 VLTVEDLTGEG----FRNISLEVRAGEILGLAGVVGAGRTELAETLYGLRPARGGRIMLNGKEINALSTAQ-RLARGLVY 342
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 86 TAVQSQ----FPEHHLAqYIVLSGKFGTIG--IHNDFEKNDLNE---AIGLlkKLGGdelVNKPYRVLSQGQRQLVLIAR 156
Cdd:PRK15439 343 LPEDRQssglYLDAPLA-WNVCALTHNRRGfwIKPARENAVLERyrrALNI--KFNH---AEQAARTLSGGNQQKVLIAK 416
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 157 ALLGKPELLILDEPCNGLDLFSRELLLEQINKLAQlpNHPTLLFVSHYTEEILPIFKNIMLLKQGEIFAQGTRDKILTEN 236
Cdd:PRK15439 417 CLEASPQLLIVDEPTRGVDVSARNDIYQLIRSIAA--QNVAVLFISSDLEEIEQMADRVLVMHQGEISGALTGAAINVDT 494
|
..
gi 915796356 237 VL 238
Cdd:PRK15439 495 IM 496
|
|
| met_CoM_red_A2 |
TIGR03269 |
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in ... |
4-235 |
1.05e-12 |
|
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in methanogenesis, methyl coenzyme M reductase, contains alpha, beta, and gamma chains. In older literature, the complex of alpha, beta, and gamma chains was termed component C, while this single chain protein was termed methyl coenzyme M reductase system component A2. [Energy metabolism, Methanogenesis]
Pssm-ID: 132313 [Multi-domain] Cd Length: 520 Bit Score: 67.52 E-value: 1.05e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 4 NAVLSMKNVS---FERDKIILK---NINWSLHSGENWVLMGLNGAGKTTLLSLIYGNHWATTGSIEVLgetFGKTNVLAL 77
Cdd:TIGR03269 277 EPIIKVRNVSkryISVDRGVVKavdNVSLEVKEGEIFGIVGTSGAGKTTLSKIIAGVLEPTSGEVNVR---VGDEWVDMT 353
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 78 KKRIGLISTAvqsqfpehhlAQYIVLSGKFGTIGIHNDFEKNdLNEAIGL--------------LKKLGGDE-----LVN 138
Cdd:TIGR03269 354 KPGPDGRGRA----------KRYIGILHQEYDLYPHRTVLDN-LTEAIGLelpdelarmkavitLKMVGFDEekaeeILD 422
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 139 KPYRVLSQGQRQLVLIARALLGKPELLILDEPCNGLDLFSRELLLEQINKlAQLPNHPTLLFVSHYTEEILPIFKNIMLL 218
Cdd:TIGR03269 423 KYPDELSEGERHRVALAQVLIKEPRIVILDEPTGTMDPITKVDVTHSILK-AREEMEQTFIIVSHDMDFVLDVCDRAALM 501
|
250
....*....|....*..
gi 915796356 219 KQGEIFAQGTRDKILTE 235
Cdd:TIGR03269 502 RDGKIVKIGDPEEIVEE 518
|
|
| MK0520 |
COG2401 |
ABC-type ATPase fused to a predicted acetyltransferase domain [General function prediction ... |
5-175 |
1.06e-12 |
|
ABC-type ATPase fused to a predicted acetyltransferase domain [General function prediction only];
Pssm-ID: 441957 [Multi-domain] Cd Length: 222 Bit Score: 65.36 E-value: 1.06e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 5 AVLSMKNVSFERDKI-ILKNINWSLHSGENWVLMGLNGAGKTTLLSLIYGNH--WATTGSIEVLGETFGktNVLALKKRI 81
Cdd:COG2401 29 IVLEAFGVELRVVERyVLRDLNLEIEPGEIVLIVGASGSGKSTLLRLLAGALkgTPVAGCVDVPDNQFG--REASLIDAI 106
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 82 GListavqsqfpehhlaqyivlsgkfgtigihndfeKNDLNEAIGLLKKLGGDELVN--KPYRVLSQGQRQLVLIARALL 159
Cdd:COG2401 107 GR----------------------------------KGDFKDAVELLNAVGLSDAVLwlRRFKELSTGQKFRFRLALLLA 152
|
170
....*....|....*.
gi 915796356 160 GKPELLILDEPCNGLD 175
Cdd:COG2401 153 ERPKLLVIDEFCSHLD 168
|
|
| ssuB |
PRK11247 |
aliphatic sulfonates transport ATP-binding subunit; Provisional |
17-223 |
1.20e-12 |
|
aliphatic sulfonates transport ATP-binding subunit; Provisional
Pssm-ID: 183055 [Multi-domain] Cd Length: 257 Bit Score: 65.85 E-value: 1.20e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 17 DKIILKNINWSLHSGENWVLMGLNGAGKTTLLSLIYGNHWATTGsiEVLGetfGKTNVLALKKRIGLIstavqsqFPEHH 96
Cdd:PRK11247 24 ERTVLNQLDLHIPAGQFVAVVGRSGCGKSTLLRLLAGLETPSAG--ELLA---GTAPLAEAREDTRLM-------FQDAR 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 97 LAQYIVLSGKFGtIGIHNDFEKNDLN--EAIGLlkklggDELVNKPYRVLSQGQRQLVLIARALLGKPELLILDEPCNGL 174
Cdd:PRK11247 92 LLPWKKVIDNVG-LGLKGQWRDAALQalAAVGL------ADRANEWPAALSGGQKQRVALARALIHRPGLLLLDEPLGAL 164
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 915796356 175 DLFSRELLLEQINKLAQlPNHPTLLFVSHYTEEILPIFKNIMLLKQGEI 223
Cdd:PRK11247 165 DALTRIEMQDLIESLWQ-QHGFTVLLVTHDVSEAVAMADRVLLIEEGKI 212
|
|
| PRK11831 |
PRK11831 |
phospholipid ABC transporter ATP-binding protein MlaF; |
1-236 |
1.24e-12 |
|
phospholipid ABC transporter ATP-binding protein MlaF;
Pssm-ID: 236997 [Multi-domain] Cd Length: 269 Bit Score: 65.94 E-value: 1.24e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 1 MTNNAVLSMKNVSFER-DKIILKNINWSLHSGENWVLMGLNGAGKTTLLSLIYGNHWATTGSIEVLGE---TFGKTNVLA 76
Cdd:PRK11831 2 QSVANLVDMRGVSFTRgNRCIFDNISLTVPRGKITAIMGPSGIGKTTLLRLIGGQIAPDHGEILFDGEnipAMSRSRLYT 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 77 LKKRIGLI--STAVQSQ--------FP--EH-HLAQYIVLSGKFGTIgihndfekndlnEAIGLlkkLGGDELvnKPYRv 143
Cdd:PRK11831 82 VRKRMSMLfqSGALFTDmnvfdnvaYPlrEHtQLPAPLLHSTVMMKL------------EAVGL---RGAAKL--MPSE- 143
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 144 LSQGQRQLVLIARALLGKPELLILDEPCNGLDLFSRELLLEQINKLaqlpNHP---TLLFVSHYTEEILPIFKNIMLLKQ 220
Cdd:PRK11831 144 LSGGMARRAALARAIALEPDLIMFDEPFVGQDPITMGVLVKLISEL----NSAlgvTCVVVSHDVPEVLSIADHAYIVAD 219
|
250
....*....|....*.
gi 915796356 221 GEIFAQGTRDKiLTEN 236
Cdd:PRK11831 220 KKIVAHGSAQA-LQAN 234
|
|
| ABC_FtsE |
cd03292 |
Cell division ATP-binding protein FtsE; The FtsEX complex resembles an ABC transporter, where ... |
21-188 |
1.47e-12 |
|
Cell division ATP-binding protein FtsE; The FtsEX complex resembles an ABC transporter, where FtsE is the ATPase and the membrane subunit FtsX resembles a permease subunit. But rather than transporting any substrate, the complex acts in cell division by undergoing conformational changes that alter the activity of cell wall hydrolases located outside the plasma membrane. The complex is widely conserved in bacteria, but also extremely divergent in sequence between different lineages
Pssm-ID: 213259 [Multi-domain] Cd Length: 214 Bit Score: 65.12 E-value: 1.47e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 21 LKNINWSLHSGENWVLMGLNGAGKTTLLSLIYGNHWATTGSIEVLGetfgkTNVLALKKR-IGL----ISTAVQSQ--FP 93
Cdd:cd03292 17 LDGINISISAGEFVFLVGPSGAGKSTLLKLIYKEELPTSGTIRVNG-----QDVSDLRGRaIPYlrrkIGVVFQDFrlLP 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 94 EHHLAQYIVLSGKFGTIGiHNDFEKN--DLNEAIGLLKKlgGDELVNKpyrvLSQGQRQLVLIARALLGKPELLILDEPC 171
Cdd:cd03292 92 DRNVYENVAFALEVTGVP-PREIRKRvpAALELVGLSHK--HRALPAE----LSGGEQQRVAIARAIVNSPTILIADEPT 164
|
170 180
....*....|....*....|
gi 915796356 172 NGLDL-FSREL--LLEQINK 188
Cdd:cd03292 165 GNLDPdTTWEImnLLKKINK 184
|
|
| ABCC_TAP |
cd03248 |
ATP-binding cassette domain of the Transporter Associated with Antigen Processing, subfamily C; ... |
10-223 |
1.63e-12 |
|
ATP-binding cassette domain of the Transporter Associated with Antigen Processing, subfamily C; TAP (Transporter Associated with Antigen Processing) is essential for peptide delivery from the cytosol into the lumen of the endoplasmic reticulum (ER), where these peptides are loaded on major histocompatibility complex (MHC) I molecules. Loaded MHC I leave the ER and display their antigenic cargo on the cell surface to cytotoxic T cells. Subsequently, virus-infected or malignantly transformed cells can be eliminated. TAP belongs to the large family of ATP-binding cassette (ABC) transporters, which translocate a vast variety of solutes across membranes.
Pssm-ID: 213215 [Multi-domain] Cd Length: 226 Bit Score: 65.18 E-value: 1.63e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 10 KNVSF----ERDKIILKNINWSLHSGENWVLMGLNGAGKTTLLSLIYGNHWATTGSIEVLGETFGKTNVLALKKRIGLIS 85
Cdd:cd03248 15 QNVTFayptRPDTLVLQDVSFTLHPGEVTALVGPSGSGKSTVVALLENFYQPQGGQVLLDGKPISQYEHKYLHSKVSLVG 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 86 T--AVQSQFPEHHLAqYIVLSGKFGTIgihndFEKNDLNEAIGLLKKL--GGDELVNKPYRVLSQGQRQLVLIARALLGK 161
Cdd:cd03248 95 QepVLFARSLQDNIA-YGLQSCSFECV-----KEAAQKAHAHSFISELasGYDTEVGEKGSQLSGGQKQRVAIARALIRN 168
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 915796356 162 PELLILDEPCNGLDLFSrELLLEQInkLAQLPNHPTLLFVSHYTEEILPIfKNIMLLKQGEI 223
Cdd:cd03248 169 PQVLILDEATSALDAES-EQQVQQA--LYDWPERRTVLVIAHRLSTVERA-DQILVLDGGRI 226
|
|
| PRK10895 |
PRK10895 |
lipopolysaccharide ABC transporter ATP-binding protein; Provisional |
5-242 |
1.75e-12 |
|
lipopolysaccharide ABC transporter ATP-binding protein; Provisional
Pssm-ID: 182817 [Multi-domain] Cd Length: 241 Bit Score: 65.30 E-value: 1.75e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 5 AVLSMKNVSFE-RDKIILKNINWSLHSGENWVLMGLNGAGKTTLLSLIYGNHWATTGSIEVLGETFgktNVLALKKR--- 80
Cdd:PRK10895 2 ATLTAKNLAKAyKGRRVVEDVSLTVNSGEIVGLLGPNGAGKTTTFYMVVGIVPRDAGNIIIDDEDI---SLLPLHARarr 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 81 -IGLISTAVqSQFpehhlAQYIVLSGKFGTIGIHNDFEKNDLNE-AIGLLKKLGGDELVNKPYRVLSQGQRQLVLIARAL 158
Cdd:PRK10895 79 gIGYLPQEA-SIF-----RRLSVYDNLMAVLQIRDDLSAEQREDrANELMEEFHIEHLRDSMGQSLSGGERRRVEIARAL 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 159 LGKPELLILDEPCNGLDLFSrellLEQINKLAQLPNHPTL--LFVSHYTEEILPIFKNIMLLKQGEIFAQGTRDKILTEN 236
Cdd:PRK10895 153 AANPKFILLDEPFAGVDPIS----VIDIKRIIEHLRDSGLgvLITDHNVRETLAVCERAYIVSQGHLIAHGTPTEILQDE 228
|
....*.
gi 915796356 237 VLSKFY 242
Cdd:PRK10895 229 HVKRVY 234
|
|
| PRK10762 |
PRK10762 |
D-ribose transporter ATP binding protein; Provisional |
21-226 |
1.87e-12 |
|
D-ribose transporter ATP binding protein; Provisional
Pssm-ID: 236755 [Multi-domain] Cd Length: 501 Bit Score: 66.57 E-value: 1.87e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 21 LKNINWSLHSGENWVLMGLNGAGKTTLLSLIYGNHWATTGSIEVLGE--TFG--KTNVLAlkkRIGLISTAVqSQFPEHH 96
Cdd:PRK10762 20 LSGAALNVYPGRVMALVGENGAGKSTMMKVLTGIYTRDAGSILYLGKevTFNgpKSSQEA---GIGIIHQEL-NLIPQLT 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 97 LAQYIVLS----GKFGTIgihnDFEKNdLNEAIGLLKKLG----GDELVNKpyrvLSQGQRQLVLIARALLGKPELLILD 168
Cdd:PRK10762 96 IAENIFLGrefvNRFGRI----DWKKM-YAEADKLLARLNlrfsSDKLVGE----LSIGEQQMVEIAKVLSFESKVIIMD 166
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 915796356 169 EPCNGLDLFSRELLLEQINKL-AQlpnHPTLLFVSHYTEEILPIFKNIMLLKQGEIFAQ 226
Cdd:PRK10762 167 EPTDALTDTETESLFRVIRELkSQ---GRGIVYISHRLKEIFEICDDVTVFRDGQFIAE 222
|
|
| PRK11176 |
PRK11176 |
lipid A ABC transporter ATP-binding protein/permease MsbA; |
7-236 |
2.02e-12 |
|
lipid A ABC transporter ATP-binding protein/permease MsbA;
Pssm-ID: 183016 [Multi-domain] Cd Length: 582 Bit Score: 66.58 E-value: 2.02e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 7 LSMKNVSF---ERDKIILKNINWSLHSGENWVLMGLNGAGKTTLLSLIYGNHWATTGSIEVLGETFGKTNVLALKKRIGL 83
Cdd:PRK11176 342 IEFRNVTFtypGKEVPALRNINFKIPAGKTVALVGRSGSGKSTIANLLTRFYDIDEGEILLDGHDLRDYTLASLRNQVAL 421
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 84 ISTAVqsqfpehHL-----AQYIVLSGKfgtigihNDFEKNDLNEA------IGLLKKL--GGDELVNKPYRVLSQGQRQ 150
Cdd:PRK11176 422 VSQNV-------HLfndtiANNIAYART-------EQYSREQIEEAarmayaMDFINKMdnGLDTVIGENGVLLSGGQRQ 487
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 151 LVLIARALLGKPELLILDEPCNGLDLFSRELLLEQINKLAQlpnHPTLLFVSHYTEEIlpifKN---IMLLKQGEIFAQG 227
Cdd:PRK11176 488 RIAIARALLRDSPILILDEATSALDTESERAIQAALDELQK---NRTSLVIAHRLSTI----EKadeILVVEDGEIVERG 560
|
....*....
gi 915796356 228 TRDKILTEN 236
Cdd:PRK11176 561 THAELLAQN 569
|
|
| YejF |
COG4172 |
ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites ... |
1-234 |
2.09e-12 |
|
ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites biosynthesis, transport and catabolism];
Pssm-ID: 443332 [Multi-domain] Cd Length: 533 Bit Score: 66.25 E-value: 2.09e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 1 MTNNAVLSMKN--VSF---ERDKIILKNINWSLHSGENWVLMGLNGAGKT----TLLSLIYGNHWATTGSIevlgeTFGK 71
Cdd:COG4172 1 MMSMPLLSVEDlsVAFgqgGGTVEAVKGVSFDIAAGETLALVGESGSGKSvtalSILRLLPDPAAHPSGSI-----LFDG 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 72 TNVLALK---------KRIGLIstavqsqFPE-------HHlaqyivlsgkfgTIG--------IHNDFEKNDLNE-AIG 126
Cdd:COG4172 76 QDLLGLSerelrrirgNRIAMI-------FQEpmtslnpLH------------TIGkqiaevlrLHRGLSGAAARArALE 136
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 127 LLKKLGGDELVNK----PYRvLSQGQRQLVLIARALLGKPELLILDEPCNGLD-------LfsrELL--LEQINKLAqlp 193
Cdd:COG4172 137 LLERVGIPDPERRldayPHQ-LSGGQRQRVMIAMALANEPDLLIADEPTTALDvtvqaqiL---DLLkdLQRELGMA--- 209
|
250 260 270 280
....*....|....*....|....*....|....*....|....*..
gi 915796356 194 nhptLLFVSHYteeiLPIFKNI------MllKQGEIFAQGTRDKILT 234
Cdd:COG4172 210 ----LLLITHD----LGVVRRFadrvavM--RQGEIVEQGPTAELFA 246
|
|
| cbiO |
PRK13649 |
energy-coupling factor transporter ATPase; |
7-235 |
3.35e-12 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184208 [Multi-domain] Cd Length: 280 Bit Score: 64.77 E-value: 3.35e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 7 LSMKNVS--------FERDKiiLKNINWSLHSGENWVLMGLNGAGKTTLLSLIYGNHWATTGSIEVLGETFGKT----NV 74
Cdd:PRK13649 3 INLQNVSytyqagtpFEGRA--LFDVNLTIEDGSYTAFIGHTGSGKSTIMQLLNGLHVPTQGSVRVDDTLITSTsknkDI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 75 LALKKRIGLIStavqsQFPEHHLAQYIVLsgKFGTIGIHNDFEKNDLNEAIGLLK-KLGG--DELVNKPYRVLSQGQRQL 151
Cdd:PRK13649 81 KQIRKKVGLVF-----QFPESQLFEETVL--KDVAFGPQNFGVSQEEAEALAREKlALVGisESLFEKNPFELSGGQMRR 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 152 VLIARALLGKPELLILDEPCNGLDLFSRELLLEQINKLAQlpNHPTLLFVSHYTEEILPIFKNIMLLKQGEIFAQGTRDK 231
Cdd:PRK13649 154 VAIAGILAMEPKILVLDEPTAGLDPKGRKELMTLFKKLHQ--SGMTIVLVTHLMDDVANYADFVYVLEKGKLVLSGKPKD 231
|
....
gi 915796356 232 ILTE 235
Cdd:PRK13649 232 IFQD 235
|
|
| PhnK |
COG1101 |
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ... |
7-203 |
3.47e-12 |
|
ABC-type uncharacterized transport system, ATPase component [General function prediction only];
Pssm-ID: 440718 [Multi-domain] Cd Length: 264 Bit Score: 64.72 E-value: 3.47e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 7 LSMKNVS--FERD----KIILKNINWSLHSGENWVLMGLNGAGKTTLLSLIYGNHWATTGSIEVLGEtfgktNVLALK-- 78
Cdd:COG1101 2 LELKNLSktFNPGtvneKRALDGLNLTIEEGDFVTVIGSNGAGKSTLLNAIAGSLPPDSGSILIDGK-----DVTKLPey 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 79 KRIGLIS---------TAvqsqfPEHHLAQYIVLS---GKFGTIGIHNDfeKNDLNEAIGLLKKLG-G--DELvNKPYRV 143
Cdd:COG1101 77 KRAKYIGrvfqdpmmgTA-----PSMTIEENLALAyrrGKRRGLRRGLT--KKRRELFRELLATLGlGleNRL-DTKVGL 148
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 144 LSQGQRQLVLIARALLGKPELLILDEPCNGLDLFSRELLLEQINKLAQlPNHPTLLFVSH 203
Cdd:COG1101 149 LSGGQRQALSLLMATLTKPKLLLLDEHTAALDPKTAALVLELTEKIVE-ENNLTTLMVTH 207
|
|
| xylG |
TIGR02633 |
D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose ... |
23-239 |
5.36e-12 |
|
D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose isomerase and xylulokinase enzymes for xylose utilization. Members of this protein family are the ATP-binding cassette (ABC) subunit of the known or predicted high-affinity xylose ABC transporter for xylose import. These genes, which closely resemble other sugar transport ABC transporter genes, typically are encoded near xylose utilization enzymes and regulatory proteins. Note that this form of the transporter contains two copies of the ABC transporter domain (pfam00005). [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]
Pssm-ID: 131681 [Multi-domain] Cd Length: 500 Bit Score: 65.23 E-value: 5.36e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 23 NINWSLHSGENWVLMGLNGAGKTTLLSLIYGNH-WATTGSIEVLGETFGKTNVL-ALKKRIGLISTAVQSQ--FPEHHLA 98
Cdd:TIGR02633 278 DVSFSLRRGEILGVAGLVGAGRTELVQALFGAYpGKFEGNVFINGKPVDIRNPAqAIRAGIAMVPEDRKRHgiVPILGVG 357
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 99 QYIVLSG--KFGTIGIHND-FEKNDLNEAIGLLK-KLGGDELvnkPYRVLSQGQRQLVLIARALLGKPELLILDEPCNGL 174
Cdd:TIGR02633 358 KNITLSVlkSFCFKMRIDAaAELQIIGSAIQRLKvKTASPFL---PIGRLSGGNQQKAVLAKMLLTNPRVLILDEPTRGV 434
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 915796356 175 DLFSRELLLEQINKLAQlpNHPTLLFVSHYTEEILPIFKNIMLLKQGEIFAQGTRDKILTENVLS 239
Cdd:TIGR02633 435 DVGAKYEIYKLINQLAQ--EGVAIIVVSSELAEVLGLSDRVLVIGEGKLKGDFVNHALTQEQVLA 497
|
|
| lolD |
PRK11629 |
lipoprotein-releasing ABC transporter ATP-binding protein LolD; |
20-189 |
6.68e-12 |
|
lipoprotein-releasing ABC transporter ATP-binding protein LolD;
Pssm-ID: 183244 [Multi-domain] Cd Length: 233 Bit Score: 63.30 E-value: 6.68e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 20 ILKNINWSLHSGENWVLMGLNGAGKTTLLSLIYGNHWATTGSIEVLGETFGKTNVLA---LKKR-IGLIStavqsQFpeH 95
Cdd:PRK11629 24 VLHNVSFSIGEGEMMAIVGSSGSGKSTLLHLLGGLDTPTSGDVIFNGQPMSKLSSAAkaeLRNQkLGFIY-----QF--H 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 96 HL-AQYIVLSGKFGTIGIHNDFEKNDLNEAIGLLKKLGGDELVNKPYRVLSQGQRQLVLIARALLGKPELLILDEPCNGL 174
Cdd:PRK11629 97 HLlPDFTALENVAMPLLIGKKKPAEINSRALEMLAAVGLEHRANHRPSELSGGERQRVAIARALVNNPRLVLADEPTGNL 176
|
170
....*....|....*
gi 915796356 175 DLFSRELLLEQINKL 189
Cdd:PRK11629 177 DARNADSIFQLLGEL 191
|
|
| ccmA |
TIGR01189 |
heme ABC exporter, ATP-binding protein CcmA; This model describes the cyt c biogenesis protein ... |
7-186 |
8.16e-12 |
|
heme ABC exporter, ATP-binding protein CcmA; This model describes the cyt c biogenesis protein encoded by ccmA in bacteria. An exception is, an arabidopsis protein. Quite likely this is encoded by an organelle. Bacterial c-type cytocromes are located on the periplasmic side of the cytoplasmic membrane. Several gene products encoded in a locus designated as 'ccm' are implicated in the transport and assembly of the functional cytochrome C. This cluster includes genes: ccmA;B;C;D;E;F;G and H. The posttranslational pathway includes the transport of heme moiety, the secretion of the apoprotein and the covalent attachment of the heme with the apoprotein. The proteins ccmA and B represent an ABC transporter; ccmC and D participate in heme transfer to ccmE, which function as a periplasmic heme chaperone. The presence of ccmF, G and H is suggested to be obligatory for the final functional assembly of cytochrome c. [Protein fate, Protein and peptide secretion and trafficking, Transport and binding proteins, Other]
Pssm-ID: 273491 [Multi-domain] Cd Length: 198 Bit Score: 62.76 E-value: 8.16e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 7 LSMKNVSFERD-KIILKNINWSLHSGENWVLMGLNGAGKTTLLSLIYGNHWATTGSIEVLGETFGKT------NVLALKK 79
Cdd:TIGR01189 1 LAARNLACSRGeRMLFEGLSFTLNAGEALQVTGPNGIGKTTLLRILAGLLRPDSGEVRWNGTPLAEQrdepheNILYLGH 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 80 RIGL---ISTAVQSQFpEHHLAQYivlsgkfgtigihndfEKNDLNEAiglLKKLGGDELVNKPYRVLSQGQRQLVLIAR 156
Cdd:TIGR01189 81 LPGLkpeLSALENLHF-WAAIHGG----------------AQRTIEDA---LAAVGLTGFEDLPAAQLSAGQQRRLALAR 140
|
170 180 190
....*....|....*....|....*....|
gi 915796356 157 ALLGKPELLILDEPCNGLDLFSRELLLEQI 186
Cdd:TIGR01189 141 LWLSRRPLWILDEPTTALDKAGVALLAGLL 170
|
|
| xylG |
TIGR02633 |
D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose ... |
6-243 |
8.46e-12 |
|
D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose isomerase and xylulokinase enzymes for xylose utilization. Members of this protein family are the ATP-binding cassette (ABC) subunit of the known or predicted high-affinity xylose ABC transporter for xylose import. These genes, which closely resemble other sugar transport ABC transporter genes, typically are encoded near xylose utilization enzymes and regulatory proteins. Note that this form of the transporter contains two copies of the ABC transporter domain (pfam00005). [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]
Pssm-ID: 131681 [Multi-domain] Cd Length: 500 Bit Score: 64.46 E-value: 8.46e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 6 VLSMKNVSFERDKI-ILKNINWSLHSGENWVLMGLNGAGKTTLLSLIYG--NHWATTGSIEVLGETFGKTNVLALKKRIG 82
Cdd:TIGR02633 1 LLEMKGIVKTFGGVkALDGIDLEVRPGECVGLCGENGAGKSTLMKILSGvyPHGTWDGEIYWSGSPLKASNIRDTERAGI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 83 LISTAVQSQFPEHHLAQYIVLSGKFGTIGIHNDFEKNDLnEAIGLLKKLGGDEL-VNKPYRVLSQGQRQLVLIARALLGK 161
Cdd:TIGR02633 81 VIIHQELTLVPELSVAENIFLGNEITLPGGRMAYNAMYL-RAKNLLRELQLDADnVTRPVGDYGGGQQQLVEIAKALNKQ 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 162 PELLILDEPCNGLDLFSRELLLEQINKLAQlpNHPTLLFVSHYTEEILPIFKNIMLLKQGEIFAQG-----TRDKILTEN 236
Cdd:TIGR02633 160 ARLLILDEPSSSLTEKETEILLDIIRDLKA--HGVACVYISHKLNEVKAVCDTICVIRDGQHVATKdmstmSEDDIITMM 237
|
250
....*....|
gi 915796356 237 V---LSKFYP 243
Cdd:TIGR02633 238 VgreITSLYP 247
|
|
| ABC_KpsT_Wzt |
cd03220 |
ATP-binding cassette component of polysaccharide transport system; The KpsT/Wzt ABC ... |
16-227 |
1.04e-11 |
|
ATP-binding cassette component of polysaccharide transport system; The KpsT/Wzt ABC transporter subfamily is involved in extracellular polysaccharide export. Among the variety of membrane-linked or extracellular polysaccharides excreted by bacteria, only capsular polysaccharides, lipopolysaccharides, and teichoic acids have been shown to be exported by ABC transporters. A typical system is made of a conserved integral membrane and an ABC. In addition to these proteins, capsular polysaccharide exporter systems require two 'accessory' proteins to perform their function: a periplasmic (E.coli) or a lipid-anchored outer membrane protein called OMA (Neisseria meningitidis and Haemophilus influenza) and a cytoplasmic membrane protein MPA2.
Pssm-ID: 213187 [Multi-domain] Cd Length: 224 Bit Score: 62.55 E-value: 1.04e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 16 RDKIILKNINWSLHSGENWVLMGLNGAGKTTLLSLIYGNHWATTGSIEVLGetfgktNVLALkkrIGLiSTAVQsqfPEH 95
Cdd:cd03220 33 GEFWALKDVSFEVPRGERIGLIGRNGAGKSTLLRLLAGIYPPDSGTVTVRG------RVSSL---LGL-GGGFN---PEL 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 96 HLAQYIVLSGKFgtIGIHNDFEKNDLNEAIGlLKKLGgdELVNKPYRVLSQGQRQLVLIARALLGKPELLILDEPCNGLD 175
Cdd:cd03220 100 TGRENIYLNGRL--LGLSRKEIDEKIDEIIE-FSELG--DFIDLPVKTYSSGMKARLAFAIATALEPDILLIDEVLAVGD 174
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 915796356 176 LFSRELLLEQINKLAQlpNHPTLLFVSHYTEEILPIFKNIMLLKQGEIFAQG 227
Cdd:cd03220 175 AAFQEKCQRRLRELLK--QGKTVILVSHDPSSIKRLCDRALVLEKGKIRFDG 224
|
|
| ABCC_CFTR2 |
cd03289 |
ATP-binding cassette domain 2 of CFTR,subfamily C; The cystic fibrosis transmembrane regulator ... |
20-253 |
1.11e-11 |
|
ATP-binding cassette domain 2 of CFTR,subfamily C; The cystic fibrosis transmembrane regulator (CFTR), the product of the gene mutated in patients with cystic fibrosis, has adapted the ABC transporter structural motif to form a tightly regulated anion channel at the apical surface of many epithelia. Use of the term assembly of a functional ion channel implies the coming together of subunits or at least smaller not-yet functional components of the active whole. In fact, on the basis of current knowledge only the CFTR polypeptide itself is required to form an ATP- and protein kinase A-dependent low-conductance chloride channel of the type present in the apical membrane of many epithelial cells. CFTR displays the typical organization (IM-ABC)2 and carries a characteristic hydrophilic R-domain that separates IM1-ABC1 from IM2-ABC2.
Pssm-ID: 213256 [Multi-domain] Cd Length: 275 Bit Score: 63.33 E-value: 1.11e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 20 ILKNINWSLHSGENWVLMGLNGAGKTTLLS----LIYgnhwaTTGSIEVLGETFGKTNVLALKKRIGLISTAVqsqfpeh 95
Cdd:cd03289 19 VLENISFSISPGQRVGLLGRTGSGKSTLLSaflrLLN-----TEGDIQIDGVSWNSVPLQKWRKAFGVIPQKV------- 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 96 hlaqyIVLSGKF----GTIGIHNDFEKNDLNEAIGL---LKKLGGD---ELVNKPYrVLSQGQRQLVLIARALLGKPELL 165
Cdd:cd03289 87 -----FIFSGTFrknlDPYGKWSDEEIWKVAEEVGLksvIEQFPGQldfVLVDGGC-VLSHGHKQLMCLARSVLSKAKIL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 166 ILDEPCNGLDLFSRELLLEqinKLAQLPNHPTLLFVSHYTEEILPIfKNIMLLKQGEIFAQGTRDKILTENVLSKFYPKP 245
Cdd:cd03289 161 LLDEPSAHLDPITYQVIRK---TLKQAFADCTVILSEHRIEAMLEC-QRFLVIEENKVRQYDSIQKLLNEKSHFKQAISP 236
|
250
....*....|.
gi 915796356 246 ---IKIFPVTN 253
Cdd:cd03289 237 sdrLKLFPRRN 247
|
|
| cbiO |
PRK13644 |
energy-coupling factor transporter ATPase; |
21-235 |
1.12e-11 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 106587 [Multi-domain] Cd Length: 274 Bit Score: 63.47 E-value: 1.12e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 21 LKNINWSLHSGENWVLMGLNGAGKTTLLSLIYGNHWATTGSIEVLGETFGKTNVL-ALKKRIGLISTAVQSQF----PEH 95
Cdd:PRK13644 18 LENINLVIKKGEYIGIIGKNGSGKSTLALHLNGLLRPQKGKVLVSGIDTGDFSKLqGIRKLVGIVFQNPETQFvgrtVEE 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 96 HLAqyivlsgkFGT-------IGIHNDFEKndlneaigLLKKLGGDELVNKPYRVLSQGQRQLVLIARALLGKPELLILD 168
Cdd:PRK13644 98 DLA--------FGPenlclppIEIRKRVDR--------ALAEIGLEKYRHRSPKTLSGGQGQCVALAGILTMEPECLIFD 161
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 915796356 169 EPCNGLDLFSRELLLEQINKLAQlpNHPTLLFVSHYTEEiLPIFKNIMLLKQGEIFAQGTRDKILTE 235
Cdd:PRK13644 162 EVTSMLDPDSGIAVLERIKKLHE--KGKTIVYITHNLEE-LHDADRIIVMDRGKIVLEGEPENVLSD 225
|
|
| MsbA_lipidA |
TIGR02203 |
lipid A export permease/ATP-binding protein MsbA; This family consists of a single polypeptide ... |
7-236 |
1.46e-11 |
|
lipid A export permease/ATP-binding protein MsbA; This family consists of a single polypeptide chain transporter in the ATP-binding cassette (ABC) transporter family, MsbA, which exports lipid A. It may also act in multidrug resistance. Lipid A, a part of lipopolysaccharide, is found in the outer leaflet of the outer membrane of most Gram-negative bacteria. Members of this family are restricted to the Proteobacteria (although lipid A is more broadly distributed) and often are clustered with lipid A biosynthesis genes. [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides, Transport and binding proteins, Other]
Pssm-ID: 131258 [Multi-domain] Cd Length: 571 Bit Score: 63.97 E-value: 1.46e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 7 LSMKNVSFE---RDKIILKNINWSLHSGENWVLMGLNGAGKTTLLSLIYGNHWATTGSIEVLGETFGKTNVLALKKRIGL 83
Cdd:TIGR02203 331 VEFRNVTFRypgRDRPALDSISLVIEPGETVALVGRSGSGKSTLVNLIPRFYEPDSGQILLDGHDLADYTLASLRRQVAL 410
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 84 ISTAVqsqfpehHLAQYIVLS----GKFGTIG---IHNDFEKNDLNEAIGLLKkLGGDELVNKPYRVLSQGQRQLVLIAR 156
Cdd:TIGR02203 411 VSQDV-------VLFNDTIANniayGRTEQADraeIERALAAAYAQDFVDKLP-LGLDTPIGENGVLLSGGQRQRLAIAR 482
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 157 ALLGKPELLILDEPCNGLDLFSRELLLEQINKLaqLPNHPTLLfVSHYTEEIlpifKN---IMLLKQGEIFAQGTRDKIL 233
Cdd:TIGR02203 483 ALLKDAPILILDEATSALDNESERLVQAALERL--MQGRTTLV-IAHRLSTI----EKadrIVVMDDGRIVERGTHNELL 555
|
...
gi 915796356 234 TEN 236
Cdd:TIGR02203 556 ARN 558
|
|
| PRK14247 |
PRK14247 |
phosphate ABC transporter ATP-binding protein; Provisional |
20-234 |
1.48e-11 |
|
phosphate ABC transporter ATP-binding protein; Provisional
Pssm-ID: 172735 [Multi-domain] Cd Length: 250 Bit Score: 62.62 E-value: 1.48e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 20 ILKNINWSLHSGENWVLMGLNGAGKTTLLSL------IYGNHwATTGSIEVLGETFGKTNVLALKKRIGLIsTAVQSQFP 93
Cdd:PRK14247 18 VLDGVNLEIPDNTITALMGPSGSGKSTLLRVfnrlieLYPEA-RVSGEVYLDGQDIFKMDVIELRRRVQMV-FQIPNPIP 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 94 EHHLAQYIVLSGKFGTIGIhndfEKNDLNEAI--GLLKKLGGDELVNK---PYRVLSQGQRQLVLIARALLGKPELLILD 168
Cdd:PRK14247 96 NLSIFENVALGLKLNRLVK----SKKELQERVrwALEKAQLWDEVKDRldaPAGKLSGGQQQRLCIARALAFQPEVLLAD 171
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 169 EPCNGLDLFS----RELLLEqinklaqLPNHPTLLFVSHYTEEILPIFKNIMLLKQGEIFAQGTRDKILT 234
Cdd:PRK14247 172 EPTANLDPENtakiESLFLE-------LKKDMTIVLVTHFPQQAARISDYVAFLYKGQIVEWGPTREVFT 234
|
|
| cbiO |
PRK13645 |
energy-coupling factor transporter ATPase; |
9-249 |
1.50e-11 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184204 [Multi-domain] Cd Length: 289 Bit Score: 63.10 E-value: 1.50e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 9 MKNVSFERDKII------LKNINWSLHSGENWVLMGLNGAGKTTLLSLIYGNHWATTGSIeVLGETFGKTN------VLA 76
Cdd:PRK13645 9 LDNVSYTYAKKTpfefkaLNNTSLTFKKNKVTCVIGTTGSGKSTMIQLTNGLIISETGQT-IVGDYAIPANlkkikeVKR 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 77 LKKRIGLIStavqsQFPEHHLAQYIVLSG-KFGTIGIHNDFEK--NDLNEAIGLLKkLGGDELVNKPYRvLSQGQRQLVL 153
Cdd:PRK13645 88 LRKEIGLVF-----QFPEYQLFQETIEKDiAFGPVNLGENKQEayKKVPELLKLVQ-LPEDYVKRSPFE-LSGGQKRRVA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 154 IARALLGKPELLILDEPCNGLDLFSRE---LLLEQINKlaqlPNHPTLLFVSHYTEEILPIFKNIMLLKQGEIFAQGTRD 230
Cdd:PRK13645 161 LAGIIAMDGNTLVLDEPTGGLDPKGEEdfiNLFERLNK----EYKKRIIMVTHNMDQVLRIADEVIVMHEGKVISIGSPF 236
|
250 260
....*....|....*....|
gi 915796356 231 KILT-ENVLSKFYPKPIKIF 249
Cdd:PRK13645 237 EIFSnQELLTKIEIDPPKLY 256
|
|
| TagH |
COG1134 |
ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate ... |
16-233 |
1.61e-11 |
|
ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate transport and metabolism];
Pssm-ID: 440749 [Multi-domain] Cd Length: 245 Bit Score: 62.41 E-value: 1.61e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 16 RDKIILKNINWSLHSGENWVLMGLNGAGKTTLLSLIYGNHWATTGSIEVLGEtfgktnVLALkkrIGLiSTAVQsqfPEH 95
Cdd:COG1134 37 EEFWALKDVSFEVERGESVGIIGRNGAGKSTLLKLIAGILEPTSGRVEVNGR------VSAL---LEL-GAGFH---PEL 103
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 96 HLAQYIVLSGkfgtiGIHNdFEKNDLNEAIgllkklggDELV---------NKPYRVLSQGQRqlvliARalLG------ 160
Cdd:COG1134 104 TGRENIYLNG-----RLLG-LSRKEIDEKF--------DEIVefaelgdfiDQPVKTYSSGMR-----AR--LAfavata 162
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 915796356 161 -KPELLILDEpcnGL---DLFSRELLLEQINKLAQlpNHPTLLFVSHYTEEILPIFKNIMLLKQGEIFAQGTRDKIL 233
Cdd:COG1134 163 vDPDILLVDE---VLavgDAAFQKKCLARIRELRE--SGRTVIFVSHSMGAVRRLCDRAIWLEKGRLVMDGDPEEVI 234
|
|
| SapD |
COG4170 |
ABC-type antimicrobial peptide export system, ATPase component SapD [Defense mechanisms]; |
123-235 |
1.86e-11 |
|
ABC-type antimicrobial peptide export system, ATPase component SapD [Defense mechanisms];
Pssm-ID: 443330 [Multi-domain] Cd Length: 331 Bit Score: 63.00 E-value: 1.86e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 123 EAIGLLKKLG----GDELVNKPYRvLSQGQRQLVLIARALLGKPELLILDEPCNGLDLFSRELLLEQINKLAQLpNHPTL 198
Cdd:COG4170 135 RAIELLHRVGikdhKDIMNSYPHE-LTEGECQKVMIAMAIANQPRLLIADEPTNAMESTTQAQIFRLLARLNQL-QGTSI 212
|
90 100 110
....*....|....*....|....*....|....*..
gi 915796356 199 LFVSHYTEEILPIFKNIMLLKQGEIFAQGTRDKILTE 235
Cdd:COG4170 213 LLISHDLESISQWADTITVLYCGQTVESGPTEQILKS 249
|
|
| cbiO |
PRK13631 |
cobalt transporter ATP-binding subunit; Provisional |
2-235 |
1.93e-11 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 237451 [Multi-domain] Cd Length: 320 Bit Score: 62.95 E-value: 1.93e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 2 TNNAVLSMKNVS--FERDKIilkninwslhsgenWVLMGLNGAGKTTLLSL----------------IYGNHWATTGSIE 63
Cdd:PRK13631 35 QENELVALNNISytFEKNKI--------------YFIIGNSGSGKSTLVTHfnglikskygtiqvgdIYIGDKKNNHELI 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 64 VLGETFGKTNVLALKKRIGLIStavqsQFPEHHLAQYIVLSG-KFGTI--GIHndfeKNDLNE-AIGLLKKLGGDE--LV 137
Cdd:PRK13631 101 TNPYSKKIKNFKELRRRVSMVF-----QFPEYQLFKDTIEKDiMFGPValGVK----KSEAKKlAKFYLNKMGLDDsyLE 171
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 138 NKPYRvLSQGQRQLVLIARALLGKPELLILDEPCNGLDLFSRELLLEQInkLAQLPNHPTLLFVSHYTEEILPIFKNIML 217
Cdd:PRK13631 172 RSPFG-LSGGQKRRVAIAGILAIQPEILIFDEPTAGLDPKGEHEMMQLI--LDAKANNKTVFVITHTMEHVLEVADEVIV 248
|
250
....*....|....*...
gi 915796356 218 LKQGEIFAQGTRDKILTE 235
Cdd:PRK13631 249 MDKGKILKTGTPYEIFTD 266
|
|
| YnjD |
COG4136 |
ABC-type uncharacterized transport system YnjBCD, ATPase component [General function ... |
7-210 |
2.00e-11 |
|
ABC-type uncharacterized transport system YnjBCD, ATPase component [General function prediction only];
Pssm-ID: 443311 [Multi-domain] Cd Length: 211 Bit Score: 61.73 E-value: 2.00e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 7 LSMKNVSFER-DKIILKNINWSLHSGENWVLMGLNGAGKTTLLSLIYGNH---WATTGSIEVLGETFgkTNVLALKKRIG 82
Cdd:COG4136 2 LSLENLTITLgGRPLLAPLSLTVAPGEILTLMGPSGSGKSTLLAAIAGTLspaFSASGEVLLNGRRL--TALPAEQRRIG 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 83 LIStavqsQ----FPehHL--AQYIVlsgkFG---TIGIHNdfEKNDLNEAiglLKKLGGDELVNKPYRVLSQGQRQLVL 153
Cdd:COG4136 80 ILF-----QddllFP--HLsvGENLA----FAlppTIGRAQ--RRARVEQA---LEEAGLAGFADRDPATLSGGQRARVA 143
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 915796356 154 IARALLGKPELLILDEPCNGLDL-----FsRELLLEQINKLaqlpNHPTLLfVSHYTEEILP 210
Cdd:COG4136 144 LLRALLAEPRALLLDEPFSKLDAalraqF-REFVFEQIRQR----GIPALL-VTHDEEDAPA 199
|
|
| met_CoM_red_A2 |
TIGR03269 |
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in ... |
7-241 |
2.38e-11 |
|
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in methanogenesis, methyl coenzyme M reductase, contains alpha, beta, and gamma chains. In older literature, the complex of alpha, beta, and gamma chains was termed component C, while this single chain protein was termed methyl coenzyme M reductase system component A2. [Energy metabolism, Methanogenesis]
Pssm-ID: 132313 [Multi-domain] Cd Length: 520 Bit Score: 63.28 E-value: 2.38e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 7 LSMKNVSFE-RDKIILKNINWSLHSGENWVLMGLNGAGKTTLLSLIYG--NHWATTGSI--------------------- 62
Cdd:TIGR03269 1 IEVKNLTKKfDGKEVLKNISFTIEEGEVLGILGRSGAGKSVLMHVLRGmdQYEPTSGRIiyhvalcekcgyverpskvge 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 63 --EVLGETFGKTNV----------LALKKRIGLISTAVQSQFPEHHLAQYIVLSgkFGTIGIHNdfeKNDLNEAIGLLKK 130
Cdd:TIGR03269 81 pcPVCGGTLEPEEVdfwnlsdklrRRIRKRIAIMLQRTFALYGDDTVLDNVLEA--LEEIGYEG---KEAVGRAVDLIEM 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 131 LGGDELVNKPYRVLSQGQRQLVLIARALLGKPELLILDEPCNGLDLFSRELLLEQINKLAQlPNHPTLLFVSHYTEEILP 210
Cdd:TIGR03269 156 VQLSHRITHIARDLSGGEKQRVVLARQLAKEPFLFLADEPTGTLDPQTAKLVHNALEEAVK-ASGISMVLTSHWPEVIED 234
|
250 260 270
....*....|....*....|....*....|.
gi 915796356 211 IFKNIMLLKQGEIFAQGTRDKiltenVLSKF 241
Cdd:TIGR03269 235 LSDKAIWLENGEIKEEGTPDE-----VVAVF 260
|
|
| PRK11264 |
PRK11264 |
putative amino-acid ABC transporter ATP-binding protein YecC; Provisional |
20-241 |
2.45e-11 |
|
putative amino-acid ABC transporter ATP-binding protein YecC; Provisional
Pssm-ID: 183063 [Multi-domain] Cd Length: 250 Bit Score: 62.07 E-value: 2.45e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 20 ILKNINWSLHSGENWVLMGLNGAGKTTLLSLIYGNHWATTGSIEV----------LGETfgKTNVLALKKRIGLIstaVQ 89
Cdd:PRK11264 18 VLHGIDLEVKPGEVVAIIGPSGSGKTTLLRCINLLEQPEAGTIRVgditidtarsLSQQ--KGLIRQLRQHVGFV---FQ 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 90 S--QFPeHHLAQYIVLSGKFGTIGihndfEKNDLNEAIG--LLKKLG--GDElvNKPYRVLSQGQRQLVLIARALLGKPE 163
Cdd:PRK11264 93 NfnLFP-HRTVLENIIEGPVIVKG-----EPKEEATARAreLLAKVGlaGKE--TSYPRRLSGGQQQRVAIARALAMRPE 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 164 LLILDEPCNGLDlfsRELLLEQINKLAQLPNHP-TLLFVSHYTEEILPIFKNIMLLKQGEIFAQGTRDKIL-------TE 235
Cdd:PRK11264 165 VILFDEPTSALD---PELVGEVLNTIRQLAQEKrTMVIVTHEMSFARDVADRAIFMDQGRIVEQGPAKALFadpqqprTR 241
|
....*.
gi 915796356 236 NVLSKF 241
Cdd:PRK11264 242 QFLEKF 247
|
|
| PRK13549 |
PRK13549 |
xylose transporter ATP-binding subunit; Provisional |
6-239 |
4.91e-11 |
|
xylose transporter ATP-binding subunit; Provisional
Pssm-ID: 184134 [Multi-domain] Cd Length: 506 Bit Score: 62.25 E-value: 4.91e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 6 VLSMKNVS----FERDKIILKNINWSLHSGENWVLMGLNGAGKTTLLSLIYGN-HWATTGSIEVLGETFGKTNVL-ALK- 78
Cdd:PRK13549 259 ILEVRNLTawdpVNPHIKRVDDVSFSLRRGEILGIAGLVGAGRTELVQCLFGAyPGRWEGEIFIDGKPVKIRNPQqAIAq 338
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 79 ---------KRIGLIstavqsqfPEHHLAQYIVLS--GKFGTIGIHND-FEKNDLNEAIGLLK-KLGGDELvnkPYRVLS 145
Cdd:PRK13549 339 giamvpedrKRDGIV--------PVMGVGKNITLAalDRFTGGSRIDDaAELKTILESIQRLKvKTASPEL---AIARLS 407
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 146 QGQRQLVLIARALLGKPELLILDEPCNGLDLFSRELLLEQINKLAQlpNHPTLLFVSHYTEEILPIFKNIMLLKQGEIFA 225
Cdd:PRK13549 408 GGNQQKAVLAKCLLLNPKILILDEPTRGIDVGAKYEIYKLINQLVQ--QGVAIIVISSELPEVLGLSDRVLVMHEGKLKG 485
|
250
....*....|....
gi 915796356 226 QGTRDKILTENVLS 239
Cdd:PRK13549 486 DLINHNLTQEQVME 499
|
|
| PRK13539 |
PRK13539 |
cytochrome c biogenesis protein CcmA; Provisional |
6-186 |
5.01e-11 |
|
cytochrome c biogenesis protein CcmA; Provisional
Pssm-ID: 237421 [Multi-domain] Cd Length: 207 Bit Score: 60.66 E-value: 5.01e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 6 VLSMKNVSFER-DKIILKNINWSLHSGENWVLMGLNGAGKTTLLSLIYGNHWATTGSIEVLGETFGKTNVLALKKRIGli 84
Cdd:PRK13539 2 MLEGEDLACVRgGRVLFSGLSFTLAAGEALVLTGPNGSGKTTLLRLIAGLLPPAAGTIKLDGGDIDDPDVAEACHYLG-- 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 85 stavqsqfpeHHLAQYIVLSgkfgtiGIHN-----DFEKNDLNEAIGLLKKLGGDELVNKPYRVLSQGQRQLVLIARALL 159
Cdd:PRK13539 80 ----------HRNAMKPALT------VAENlefwaAFLGGEELDIAAALEAVGLAPLAHLPFGYLSAGQKRRVALARLLV 143
|
170 180
....*....|....*....|....*..
gi 915796356 160 GKPELLILDEPCNGLDLFSRELLLEQI 186
Cdd:PRK13539 144 SNRPIWILDEPTAALDAAAVALFAELI 170
|
|
| LPS_export_lptB |
TIGR04406 |
LPS export ABC transporter ATP-binding protein; Members of this fmaily are LptB, the ... |
6-233 |
5.16e-11 |
|
LPS export ABC transporter ATP-binding protein; Members of this fmaily are LptB, the ATP-binding cassette protein of an ABC transporter involved in lipopolysaccharide export. [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides, Transport and binding proteins, Other]
Pssm-ID: 275199 [Multi-domain] Cd Length: 239 Bit Score: 61.14 E-value: 5.16e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 6 VLSMKNV--SFERDKIIlKNINWSLHSGENWVLMGLNGAGKTTLLSLIYGNHWATTGSIEVLGETFGKTNvLALKKRIGl 83
Cdd:TIGR04406 1 TLVAENLikSYKKRKVV-NDVSLSVKSGEIVGLLGPNGAGKTTSFYMIVGLVRPDAGKILIDGQDITHLP-MHERARLG- 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 84 ISTAVQ--SQFPEHHLAQYI--VLSgkfgtigIHNDFEKNDLNEAI-GLLKKLGGDELVNKPYRVLSQGQRQLVLIARAL 158
Cdd:TIGR04406 78 IGYLPQeaSIFRKLTVEENImaVLE-------IRKDLDRAEREERLeALLEEFQISHLRDNKAMSLSGGERRRVEIARAL 150
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 915796356 159 LGKPELLILDEPCNGLDLFSRELLLEQINKLAQlpNHPTLLFVSHYTEEILPIFKNIMLLKQGEIFAQGTRDKIL 233
Cdd:TIGR04406 151 ATNPKFILLDEPFAGVDPIAVGDIKKIIKHLKE--RGIGVLITDHNVRETLDICDRAYIISDGKVLAEGTPAEIV 223
|
|
| PRK10982 |
PRK10982 |
galactose/methyl galaxtoside transporter ATP-binding protein; Provisional |
9-222 |
5.41e-11 |
|
galactose/methyl galaxtoside transporter ATP-binding protein; Provisional
Pssm-ID: 182880 [Multi-domain] Cd Length: 491 Bit Score: 62.05 E-value: 5.41e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 9 MKNVSFERDKI-ILKNINWSLHSGENWVLMGLNGAGKTTLLSLIYGNHWATTGSIEVLGETFG-KTNVLALKKRIGLIST 86
Cdd:PRK10982 1 MSNISKSFPGVkALDNVNLKVRPHSIHALMGENGAGKSTLLKCLFGIYQKDSGSILFQGKEIDfKSSKEALENGISMVHQ 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 87 AVqSQFPEHHLAQYIVLsGKFGTIGIHNDFEKNdLNEAIGLLKKLGGDELVNKPYRVLSQGQRQLVLIARALLGKPELLI 166
Cdd:PRK10982 81 EL-NLVLQRSVMDNMWL-GRYPTKGMFVDQDKM-YRDTKAIFDELDIDIDPRAKVATLSVSQMQMIEIAKAFSYNAKIVI 157
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 915796356 167 LDEPCNGLDLFSRELLLEQINKLAQlpNHPTLLFVSHYTEEILPIFKNIMLLKQGE 222
Cdd:PRK10982 158 MDEPTSSLTEKEVNHLFTIIRKLKE--RGCGIVYISHKMEEIFQLCDEITILRDGQ 211
|
|
| PRK14271 |
PRK14271 |
phosphate ABC transporter ATP-binding protein; Provisional |
18-234 |
6.27e-11 |
|
phosphate ABC transporter ATP-binding protein; Provisional
Pssm-ID: 172759 [Multi-domain] Cd Length: 276 Bit Score: 61.27 E-value: 6.27e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 18 KIILKNINWSLHSGENWVLMGLNGAGKTTLLSLIYG-----NHWATTGSIEVLGET-FGKTNVLALKKRIGLISTAvQSQ 91
Cdd:PRK14271 34 KTVLDQVSMGFPARAVTSLMGPTGSGKTTFLRTLNRmndkvSGYRYSGDVLLGGRSiFNYRDVLEFRRRVGMLFQR-PNP 112
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 92 FPEHHLAQyiVLSGkfgtIGIHNDFEKNDLNE-AIGLLKKLG-----GDELVNKPYRvLSQGQRQLVLIARALLGKPELL 165
Cdd:PRK14271 113 FPMSIMDN--VLAG----VRAHKLVPRKEFRGvAQARLTEVGlwdavKDRLSDSPFR-LSGGQQQLLCLARTLAVNPEVL 185
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 915796356 166 ILDEPCNGLDLFSRELLLEQINKLAqlpNHPTLLFVSHYTEEILPIFKNIMLLKQGEIFAQGTRDKILT 234
Cdd:PRK14271 186 LLDEPTSALDPTTTEKIEEFIRSLA---DRLTVIIVTHNLAQAARISDRAALFFDGRLVEEGPTEQLFS 251
|
|
| PRK11147 |
PRK11147 |
ABC transporter ATPase component; Reviewed |
6-203 |
6.64e-11 |
|
ABC transporter ATPase component; Reviewed
Pssm-ID: 236861 [Multi-domain] Cd Length: 635 Bit Score: 61.89 E-value: 6.64e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 6 VLSMKNVSFE-RDKIILKNINWSLHSGENWVLMGLNGAGKTTLLSLIYGNHWATTGSIEV-------------------- 64
Cdd:PRK11147 319 VFEMENVNYQiDGKQLVKDFSAQVQRGDKIALIGPNGCGKTTLLKLMLGQLQADSGRIHCgtklevayfdqhraeldpek 398
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 65 -----LGEtfGKTNVLalkkriglistaVQSQfPEHHLaqyivlsgkfgtiGIHNDFekndlneaigllkkLGGDELVNK 139
Cdd:PRK11147 399 tvmdnLAE--GKQEVM------------VNGR-PRHVL-------------GYLQDF--------------LFHPKRAMT 436
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 915796356 140 PYRVLSQGQRQLVLIARALLGKPELLILDEPCNGLDLFSRElLLEQInklaqLPNHP-TLLFVSH 203
Cdd:PRK11147 437 PVKALSGGERNRLLLARLFLKPSNLLILDEPTNDLDVETLE-LLEEL-----LDSYQgTVLLVSH 495
|
|
| PRK13651 |
PRK13651 |
cobalt transporter ATP-binding subunit; Provisional |
10-236 |
1.44e-10 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 184210 [Multi-domain] Cd Length: 305 Bit Score: 60.49 E-value: 1.44e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 10 KNVSFERDKII------LKNINWSLHSGENWVLMGLNGAGKTTLLSLIYGNHWATTGSIE-------------------- 63
Cdd:PRK13651 6 KNIVKIFNKKLptelkaLDNVSVEINQGEFIAIIGQTGSGKTTFIEHLNALLLPDTGTIEwifkdeknkkktkekekvle 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 64 --VLGETFGK--TNVLALKKRIGlistaVQSQFPEHHL-AQYIVLSGKFGTIGIhnDFEKNDLNE-AIGLLKKLGGDE-- 135
Cdd:PRK13651 86 klVIQKTRFKkiKKIKEIRRRVG-----VVFQFAEYQLfEQTIEKDIIFGPVSM--GVSKEEAKKrAAKYIELVGLDEsy 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 136 LVNKPYRvLSQGQRQLVLIARALLGKPELLILDEPCNGLDLFSRELLLEQINKLAQlpNHPTLLFVSHYTEEILPIFKNI 215
Cdd:PRK13651 159 LQRSPFE-LSGGQKRRVALAGILAMEPDFLVFDEPTAGLDPQGVKEILEIFDNLNK--QGKTIILVTHDLDNVLEWTKRT 235
|
250 260
....*....|....*....|.
gi 915796356 216 MLLKQGEIFAQGTRDKILTEN 236
Cdd:PRK13651 236 IFFKDGKIIKDGDTYDILSDN 256
|
|
| ABCC_MRP_domain1 |
cd03250 |
ATP-binding cassette domain 1 of multidrug resistance-associated protein, subfamily C; This ... |
7-222 |
2.95e-10 |
|
ATP-binding cassette domain 1 of multidrug resistance-associated protein, subfamily C; This subfamily is also known as MRP (multidrug resistance-associated protein). Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resisting lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions, such as glutathione, glucuronate, and sulfate.
Pssm-ID: 213217 [Multi-domain] Cd Length: 204 Bit Score: 58.25 E-value: 2.95e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 7 LSMKNVSF------ERDKIILKNINWSLHSGENWVLMGLNGAGKTTLLSLIYGNHWATTGSIEVLGetfgktnvlalkkr 80
Cdd:cd03250 1 ISVEDASFtwdsgeQETSFTLKDINLEVPKGELVAIVGPVGSGKSSLLSALLGELEKLSGSVSVPG-------------- 66
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 81 igliSTAVQSQFPehhlaqYIVlsgkFGTI--GI--HNDFEKNDLNEAI---GLLKKL----GGDEL------VNkpyrv 143
Cdd:cd03250 67 ----SIAYVSQEP------WIQ----NGTIreNIlfGKPFDEERYEKVIkacALEPDLeilpDGDLTeigekgIN----- 127
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 144 LSQGQRQLVLIARALLGKPELLILDEPCNGLDLFSRELLLEQ-INKLaqLPNHPTLLFVSHyTEEILPIFKNIMLLKQGE 222
Cdd:cd03250 128 LSGGQKQRISLARAVYSDADIYLLDDPLSAVDAHVGRHIFENcILGL--LLNNKTRILVTH-QLQLLPHADQIVVLDNGR 204
|
|
| ABCD_peroxisomal_ALDP |
cd03223 |
ATP-binding cassette domain of peroxisomal transporter, subfamily D; Peroxisomal ATP-binding ... |
7-203 |
3.20e-10 |
|
ATP-binding cassette domain of peroxisomal transporter, subfamily D; Peroxisomal ATP-binding cassette transporter (Pat) is involved in the import of very long-chain fatty acids (VLCFA) into the peroxisome. The peroxisomal membrane forms a permeability barrier for a wide variety of metabolites required for and formed during fatty acid beta-oxidation. To communicate with the cytoplasm and mitochondria, peroxisomes need dedicated proteins to transport such hydrophilic molecules across their membranes. X-linked adrenoleukodystrophy (X-ALD) is caused by mutations in the ALD gene, which encodes ALDP (adrenoleukodystrophy protein ), a peroxisomal integral membrane protein that is a member of the ATP-binding cassette (ABC) transporter protein family. The disease is characterized by a striking and unpredictable variation in phenotypic expression. Phenotypes include the rapidly progressive childhood cerebral form (CCALD), the milder adult form, adrenomyeloneuropathy (AMN), and variants without neurologic involvement (i.e. asymptomatic).
Pssm-ID: 213190 [Multi-domain] Cd Length: 166 Bit Score: 57.55 E-value: 3.20e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 7 LSMKNVSF--ERDKIILKNINWSLHSGENWVLMGLNGAGKTTLLSLIYGnHW-ATTGSIEVLGetfgKTNVLALkkrigl 83
Cdd:cd03223 1 IELENLSLatPDGRVLLKDLSFEIKPGDRLLITGPSGTGKSSLFRALAG-LWpWGSGRIGMPE----GEDLLFL------ 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 84 istavqSQFPehhlaqYIVLsgkfgtigihndfekndlneaiGLLKklggdELVNKP-YRVLSQGQRQLVLIARALLGKP 162
Cdd:cd03223 70 ------PQRP------YLPL----------------------GTLR-----EQLIYPwDDVLSGGEQQRLAFARLLLHKP 110
|
170 180 190 200
....*....|....*....|....*....|....*....|.
gi 915796356 163 ELLILDEPCNGLDLFSRELLLEQINKLaqlpnHPTLLFVSH 203
Cdd:cd03223 111 KFVFLDEATSALDEESEDRLYQLLKEL-----GITVISVGH 146
|
|
| PRK13540 |
PRK13540 |
cytochrome c biogenesis protein CcmA; Provisional |
6-186 |
3.21e-10 |
|
cytochrome c biogenesis protein CcmA; Provisional
Pssm-ID: 184127 [Multi-domain] Cd Length: 200 Bit Score: 58.04 E-value: 3.21e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 6 VLSMKNVSFE-RDKIILKNINWSLHSGENWVLMGLNGAGKTTLLSLIYGNHWATTGSIEVLGETFGKtNVLALKKRIGLI 84
Cdd:PRK13540 1 MLDVIELDFDyHDQPLLQQISFHLPAGGLLHLKGSNGAGKTTLLKLIAGLLNPEKGEILFERQSIKK-DLCTYQKQLCFV 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 85 S--TAVQSQFPEHHLAQYivlsgkfgtiGIHNDFEKNDLNEAIGLLkKLGgdELVNKPYRVLSQGQRQLVLIARALLGKP 162
Cdd:PRK13540 80 GhrSGINPYLTLRENCLY----------DIHFSPGAVGITELCRLF-SLE--HLIDYPCGLLSSGQKRQVALLRLWMSKA 146
|
170 180
....*....|....*....|....
gi 915796356 163 ELLILDEPCNGLDLFSRELLLEQI 186
Cdd:PRK13540 147 KLWLLDEPLVALDELSLLTIITKI 170
|
|
| CFTR_protein |
TIGR01271 |
cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis ... |
20-250 |
5.48e-10 |
|
cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis fibrosis transmembrane conductor regulator (CFTR) in eukaryotes. The principal role of this protein is chloride ion conductance. The protein is predicted to consist of 12 transmembrane domains. Mutations or lesions in the genetic loci have been linked to the aetiology of asthma, bronchiectasis, chronic obstructive pulmonary disease etc. Disease-causing mutations have been studied by 36Cl efflux assays in vitro cell cultures and electrophysiology, all of which point to the impairment of chloride channel stability and not the biosynthetic processing per se. [Transport and binding proteins, Anions]
Pssm-ID: 273530 [Multi-domain] Cd Length: 1490 Bit Score: 59.54 E-value: 5.48e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 20 ILKNINWSLHSGENWVLMGLNGAGKTTLLSLIYgNHWATTGSIEVLGETFGKTNVLALKKRIGLISTAVqsqfpehhlaq 99
Cdd:TIGR01271 1234 VLQDLSFSVEGGQRVGLLGRTGSGKSTLLSALL-RLLSTEGEIQIDGVSWNSVTLQTWRKAFGVIPQKV----------- 1301
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 100 yIVLSGKF-GTIGIHNDFEKNDL---NEAIGL---LKKLGGD---ELVNKPYrVLSQGQRQLVLIARALLGKPELLILDE 169
Cdd:TIGR01271 1302 -FIFSGTFrKNLDPYEQWSDEEIwkvAEEVGLksvIEQFPDKldfVLVDGGY-VLSNGHKQLMCLARSILSKAKILLLDE 1379
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 170 PCNGLDLFSRELLLEqinKLAQLPNHPTLLFVSHYTEEILPIfKNIMLLKQGEIFAQGTRDKILTENVLSKFYPKP---I 246
Cdd:TIGR01271 1380 PSAHLDPVTLQIIRK---TLKQSFSNCTVILSEHRVEALLEC-QQFLVIEGSSVKQYDSIQKLLNETSLFKQAMSAadrL 1455
|
....
gi 915796356 247 KIFP 250
Cdd:TIGR01271 1456 KLFP 1459
|
|
| ABC_CcmA_heme_exporter |
cd03231 |
Cytochrome c biogenesis ATP-binding export protein; CcmA, the ATP-binding component of the ... |
7-186 |
7.43e-10 |
|
Cytochrome c biogenesis ATP-binding export protein; CcmA, the ATP-binding component of the bacterial CcmAB transporter. The CCM family is involved in bacterial cytochrome c biogenesis. Cytochrome c maturation in E. coli requires the ccm operon, which encodes eight membrane proteins (CcmABCDEFGH). CcmE is a periplasmic heme chaperon that binds heme covalently and transfers it onto apocytochrome c in the presence of CcmF, CcmG, and CcmH. The CcmAB proteins represent an ABC transporter and the CcmCD proteins participate in heme transfer to CcmE.
Pssm-ID: 213198 [Multi-domain] Cd Length: 201 Bit Score: 57.12 E-value: 7.43e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 7 LSMKNVSFERD-KIILKNINWSLHSGENWVLMGLNGAGKTTLLSLIYGNHWATTGsievlgetfgktnvlalkkRIGLIS 85
Cdd:cd03231 1 LEADELTCERDgRALFSGLSFTLAAGEALQVTGPNGSGKTTLLRILAGLSPPLAG-------------------RVLLNG 61
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 86 TAVQSQFPEhhLAQYIVLSGkfgtigiHNDFEKNDLN--EAIGLLKKLGGDELV-------------NKPYRVLSQGQRQ 150
Cdd:cd03231 62 GPLDFQRDS--IARGLLYLG-------HAPGIKTTLSvlENLRFWHADHSDEQVeealarvglngfeDRPVAQLSAGQQR 132
|
170 180 190
....*....|....*....|....*....|....*.
gi 915796356 151 LVLIARALLGKPELLILDEPCNGLDLFSRELLLEQI 186
Cdd:cd03231 133 RVALARLLLSGRPLWILDEPTTALDKAGVARFAEAM 168
|
|
| PRK14239 |
PRK14239 |
phosphate transporter ATP-binding protein; Provisional |
1-203 |
8.27e-10 |
|
phosphate transporter ATP-binding protein; Provisional
Pssm-ID: 184585 [Multi-domain] Cd Length: 252 Bit Score: 57.86 E-value: 8.27e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 1 MTNnAVLSMKNVS-FERDKIILKNINWSLHSGENWVLMGLNGAGKTTLLSLIygNHW-------ATTGSIEVLGETF--G 70
Cdd:PRK14239 1 MTE-PILQVSDLSvYYNKKKALNSVSLDFYPNEITALIGPSGSGKSTLLRSI--NRMndlnpevTITGSIVYNGHNIysP 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 71 KTNVLALKKRIGLISTAvQSQFPeHHLAQYIVLSGKFGtiGIHndfEKNDLNEAIGllKKLGG----DELVNKPYRV--- 143
Cdd:PRK14239 78 RTDTVDLRKEIGMVFQQ-PNPFP-MSIYENVVYGLRLK--GIK---DKQVLDEAVE--KSLKGasiwDEVKDRLHDSalg 148
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 144 LSQGQRQLVLIARALLGKPELLILDEPCNGLDLFSRELLLEqinKLAQLPNHPTLLFVSH 203
Cdd:PRK14239 149 LSGGQQQRVCIARVLATSPKIILLDEPTSALDPISAGKIEE---TLLGLKDDYTMLLVTR 205
|
|
| PRK15134 |
PRK15134 |
microcin C ABC transporter ATP-binding protein YejF; Provisional |
5-234 |
8.68e-10 |
|
microcin C ABC transporter ATP-binding protein YejF; Provisional
Pssm-ID: 237917 [Multi-domain] Cd Length: 529 Bit Score: 58.56 E-value: 8.68e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 5 AVLSMKNVSF-----ERDKIILKNINWSLHSGENWVLMGLNGAGKT-TLLSL---------IYgnhwaTTGSIEVLGETF 69
Cdd:PRK15134 4 PLLAIENLSVafrqqQTVRTVVNDVSLQIEAGETLALVGESGSGKSvTALSIlrllpsppvVY-----PSGDIRFHGESL 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 70 GKTNVLALKK----RIGLI-STAVQSQFPEHHLAQ--YIVLSgkfgtigIHNDFEKNDLN-EAIGLLKKLG----GDELV 137
Cdd:PRK15134 79 LHASEQTLRGvrgnKIAMIfQEPMVSLNPLHTLEKqlYEVLS-------LHRGMRREAARgEILNCLDRVGirqaAKRLT 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 138 NKPYRvLSQGQRQLVLIARALLGKPELLILDEPCNGLDLFSRELLLEQINKLAQLPNHpTLLFVSHYTEEILPIFKNIML 217
Cdd:PRK15134 152 DYPHQ-LSGGERQRVMIAMALLTRPELLIADEPTTALDVSVQAQILQLLRELQQELNM-GLLFITHNLSIVRKLADRVAV 229
|
250
....*....|....*..
gi 915796356 218 LKQGEIFAQGTRDKILT 234
Cdd:PRK15134 230 MQNGRCVEQNRAATLFS 246
|
|
| PRK10789 |
PRK10789 |
SmdA family multidrug ABC transporter permease/ATP-binding protein; |
17-235 |
1.00e-09 |
|
SmdA family multidrug ABC transporter permease/ATP-binding protein;
Pssm-ID: 182732 [Multi-domain] Cd Length: 569 Bit Score: 58.57 E-value: 1.00e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 17 DKIILKNINWSLHSGENWVLMGLNGAGKTTLLSLIYGNHWATTGSIEVLGETFGKTNVLALKKRIglistAVQSQFP--- 93
Cdd:PRK10789 327 DHPALENVNFTLKPGQMLGICGPTGSGKSTLLSLIQRHFDVSEGDIRFHDIPLTKLQLDSWRSRL-----AVVSQTPflf 401
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 94 EHHLAQYIVLSgkfgtigiHNDFEKNDLNEAIGL------LKKL--GGDELVNKPYRVLSQGQRQLVLIARALLGKPELL 165
Cdd:PRK10789 402 SDTVANNIALG--------RPDATQQEIEHVARLasvhddILRLpqGYDTEVGERGVMLSGGQKQRISIARALLLNAEIL 473
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 915796356 166 ILDEPCNGLDLFSRELLLEQinkLAQLPNHPTLLFVSH----YTEEilpifKNIMLLKQGEIFAQGTRDKILTE 235
Cdd:PRK10789 474 ILDDALSAVDGRTEHQILHN---LRQWGEGRTVIISAHrlsaLTEA-----SEILVMQHGHIAQRGNHDQLAQQ 539
|
|
| 3a01205 |
TIGR00956 |
Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other] |
2-190 |
1.02e-09 |
|
Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other]
Pssm-ID: 273362 [Multi-domain] Cd Length: 1394 Bit Score: 58.58 E-value: 1.02e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 2 TNNAVLSMKNVSFE-----RDKIILKNINWSLHSGENWVLMGLNGAGKTTLLSLIYGNhwATTGSIEV---------LGE 67
Cdd:TIGR00956 755 SGEDIFHWRNLTYEvkikkEKRVILNNVDGWVKPGTLTALMGASGAGKTTLLNVLAER--VTTGVITGgdrlvngrpLDS 832
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 68 TFgktnvlalKKRIGListaVQSQfpEHHLAQYIV-----LSGKFGTIGIHNDFEKNDLNEAIglLKKLG----GDELVN 138
Cdd:TIGR00956 833 SF--------QRSIGY----VQQQ--DLHLPTSTVreslrFSAYLRQPKSVSKSEKMEYVEEV--IKLLEmesyADAVVG 896
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 915796356 139 KPYRVLSQGQRQLVLIARALLGKPELLI-LDEPCNGLDLFSRELLLEQINKLA 190
Cdd:TIGR00956 897 VPGEGLNVEQRKRLTIGVELVAKPKLLLfLDEPTSGLDSQTAWSICKLMRKLA 949
|
|
| MRP_assoc_pro |
TIGR00957 |
multi drug resistance-associated protein (MRP); This model describes multi drug ... |
19-223 |
1.28e-09 |
|
multi drug resistance-associated protein (MRP); This model describes multi drug resistance-associated protein (MRP) in eukaryotes. The multidrug resistance-associated protein is an integral membrane protein that causes multidrug resistance when overexpressed in mammalian cells. It belongs to ABC transporter superfamily. The protein topology and function was experimentally demonstrated by epitope tagging and immunofluorescence. Insertion of tags in the critical regions associated with drug efflux, abrogated its function. The C-terminal domain seem to highly conserved. [Transport and binding proteins, Other]
Pssm-ID: 188098 [Multi-domain] Cd Length: 1522 Bit Score: 58.42 E-value: 1.28e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 19 IILKNINWSLHSGENWVLMGLNGAGKTTLLSLIYGNHWATTGSIEVLGETFGKTNVLALKKRIGLIStavqsQFPehhla 98
Cdd:TIGR00957 1300 LVLRHINVTIHGGEKVGIVGRTGAGKSSLTLGLFRINESAEGEIIIDGLNIAKIGLHDLRFKITIIP-----QDP----- 1369
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 99 qyIVLSGK-------FGTIGIHNDFEKNDLNEAIGLLKKL--GGDELVNKPYRVLSQGQRQLVLIARALLGKPELLILDE 169
Cdd:TIGR00957 1370 --VLFSGSlrmnldpFSQYSDEEVWWALELAHLKTFVSALpdKLDHECAEGGENLSVGQRQLVCLARALLRKTKILVLDE 1447
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 915796356 170 PCNGLDLFSRELLLEQINklAQLPNhPTLLFVSHYTEEILPiFKNIMLLKQGEI 223
Cdd:TIGR00957 1448 ATAAVDLETDNLIQSTIR--TQFED-CTVLTIAHRLNTIMD-YTRVIVLDKGEV 1497
|
|
| araG |
PRK11288 |
L-arabinose ABC transporter ATP-binding protein AraG; |
24-244 |
1.29e-09 |
|
L-arabinose ABC transporter ATP-binding protein AraG;
Pssm-ID: 183077 [Multi-domain] Cd Length: 501 Bit Score: 58.00 E-value: 1.29e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 24 INWSLHSGENWVLMGLNGAGKTTLLSLIYGNHWATTGSIEVLGETFGKTNV-------LAL----KKRIGLIstavqsqf 92
Cdd:PRK11288 272 ISFSVRAGEIVGLFGLVGAGRSELMKLLYGATRRTAGQVYLDGKPIDIRSPrdairagIMLcpedRKAEGII-------- 343
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 93 PEHHLAQYIVLSG-----KFGTIgIHNDFEKNDLNEAIGLL--KKLGGDELVnkpyRVLSQGQRQLVLIARALLGKPELL 165
Cdd:PRK11288 344 PVHSVADNINISArrhhlRAGCL-INNRWEAENADRFIRSLniKTPSREQLI----MNLSGGNQQKAILGRWLSEDMKVI 418
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 915796356 166 ILDEPCNGLDLFSRELLLEQINKLAQlpNHPTLLFVSHYTEEILPIFKNIMLLKQGEIFAQGTRDKILTENVLSKFYPK 244
Cdd:PRK11288 419 LLDEPTRGIDVGAKHEIYNVIYELAA--QGVAVLFVSSDLPEVLGVADRIVVMREGRIAGELAREQATERQALSLALPR 495
|
|
| ABCG_PDR_domain1 |
cd03233 |
First domain of the pleiotropic drug resistance-like subfamily G of ATP-binding cassette ... |
5-227 |
1.30e-09 |
|
First domain of the pleiotropic drug resistance-like subfamily G of ATP-binding cassette transporters; The pleiotropic drug resistance (PDR) is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. This PDR subfamily represents domain I of its (ABC-IM)2 organization. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds including sugars, ions, peptides, and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213200 [Multi-domain] Cd Length: 202 Bit Score: 56.50 E-value: 1.30e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 5 AVLSMKNVSF----ERDKI-ILKNINWSLHSGENWVLMGLNGAGKTTLLSLIyGNHWATTGSIEvlGE-TF-GKTNVLAL 77
Cdd:cd03233 2 STLSWRNISFttgkGRSKIpILKDFSGVVKPGEMVLVLGRPGSGCSTLLKAL-ANRTEGNVSVE--GDiHYnGIPYKEFA 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 78 KKRIGLISTAVQSqfpEHHLAQYIVlsgkFGTIgihnDFekndlneAIgllkKLGGDELVnkpyRVLSQGQRQLVLIARA 157
Cdd:cd03233 79 EKYPGEIIYVSEE---DVHFPTLTV----RETL----DF-------AL----RCKGNEFV----RGISGGERKRVSIAEA 132
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 158 LLGKPELLILDEPCNGLDLFSRELLLEQINKLAQLPNHPTLLFVSHYTEEILPIFKNIMLLKQGEIFAQG 227
Cdd:cd03233 133 LVSRASVLCWDNSTRGLDSSTALEILKCIRTMADVLKTTTFVSLYQASDEIYDLFDKVLVLYEGRQIYYG 202
|
|
| PTZ00265 |
PTZ00265 |
multidrug resistance protein (mdr1); Provisional |
7-203 |
3.15e-09 |
|
multidrug resistance protein (mdr1); Provisional
Pssm-ID: 240339 [Multi-domain] Cd Length: 1466 Bit Score: 57.35 E-value: 3.15e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 7 LSMKNVSFE----RDKIILKNINWSLHSGENWVLMGLNGAGKTTLLSLIYGNHWATTGSIEVL-GETFGKTNVLALKKRI 81
Cdd:PTZ00265 383 IQFKNVRFHydtrKDVEIYKDLNFTLTEGKTYAFVGESGCGKSTILKLIERLYDPTEGDIIINdSHNLKDINLKWWRSKI 462
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 82 GLIST------------------------AVQSQFPEHHLAQY----------IVLSGKF----------GTIGIHNDFE 117
Cdd:PTZ00265 463 GVVSQdpllfsnsiknnikyslyslkdleALSNYYNEDGNDSQenknkrnscrAKCAGDLndmsnttdsnELIEMRKNYQ 542
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 118 KNDLNEAIGLLKKL-----------GGDELVNKPYRVLSQGQRQLVLIARALLGKPELLILDEPCNGLDLFSRELLLEQI 186
Cdd:PTZ00265 543 TIKDSEVVDVSKKVlihdfvsalpdKYETLVGSNASKLSGGQKQRISIARAIIRNPKILILDEATSSLDNKSEYLVQKTI 622
|
250
....*....|....*..
gi 915796356 187 NKLAQLPNHPTLLfVSH 203
Cdd:PTZ00265 623 NNLKGNENRITII-IAH 638
|
|
| ycf16 |
CHL00131 |
sulfate ABC transporter protein; Validated |
1-228 |
4.45e-09 |
|
sulfate ABC transporter protein; Validated
Pssm-ID: 214372 [Multi-domain] Cd Length: 252 Bit Score: 55.42 E-value: 4.45e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 1 MTNNAVLSMKNVSFERDKI-ILKNINWSLHSGENWVLMGLNGAGKTTLLSLIYGnHWA---TTGSIEVLGETF------- 69
Cdd:CHL00131 2 NKNKPILEIKNLHASVNENeILKGLNLSINKGEIHAIMGPNGSGKSTLSKVIAG-HPAykiLEGDILFKGESIldlepee 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 70 -----------------GKTNVLALkkRIGLISTAVQSQFPE-HHLAQYIVLSGKFGTIGIHNDFEKNDLNEAIGllkkl 131
Cdd:CHL00131 81 rahlgiflafqypieipGVSNADFL--RLAYNSKRKFQGLPElDPLEFLEIINEKLKLVGMDPSFLSRNVNEGFS----- 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 132 GGDELVNKpyrvlsqgqrqlvlIARALLGKPELLILDEPCNGLDLFSRELLLEQINKLAQLPNhpTLLFVSHYT---EEI 208
Cdd:CHL00131 154 GGEKKRNE--------------ILQMALLDSELAILDETDSGLDIDALKIIAEGINKLMTSEN--SIILITHYQrllDYI 217
|
250 260
....*....|....*....|
gi 915796356 209 LPIFKNIMllKQGEIFAQGT 228
Cdd:CHL00131 218 KPDYVHVM--QNGKIIKTGD 235
|
|
| PRK14267 |
PRK14267 |
phosphate ABC transporter ATP-binding protein; Provisional |
20-242 |
4.91e-09 |
|
phosphate ABC transporter ATP-binding protein; Provisional
Pssm-ID: 184596 [Multi-domain] Cd Length: 253 Bit Score: 55.62 E-value: 4.91e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 20 ILKNINWSLHSGENWVLMGLNGAGKTTLLS----LIYGNHWA-TTGSIEVLGETF--GKTNVLALKKRIGLIstaVQSQF 92
Cdd:PRK14267 19 VIKGVDLKIPQNGVFALMGPSGCGKSTLLRtfnrLLELNEEArVEGEVRLFGRNIysPDVDPIEVRREVGMV---FQYPN 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 93 PEHHLAQY--IVLSGKFGTIGIhndfEKNDLNEAIG-LLKKLG-----GDELVNKPYRvLSQGQRQLVLIARALLGKPEL 164
Cdd:PRK14267 96 PFPHLTIYdnVAIGVKLNGLVK----SKKELDERVEwALKKAAlwdevKDRLNDYPSN-LSGGQRQRLVIARALAMKPKI 170
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 165 LILDEPCNGLDLFS----RELLLEqinklaqLPNHPTLLFVSHYTEEILPIFKNIMLLKQGEIFAQGTRDKILT--ENVL 238
Cdd:PRK14267 171 LLMDEPTANIDPVGtakiEELLFE-------LKKEYTIVLVTHSPAQAARVSDYVAFLYLGKLIEVGPTRKVFEnpEHEL 243
|
....
gi 915796356 239 SKFY 242
Cdd:PRK14267 244 TEKY 247
|
|
| PRK13657 |
PRK13657 |
glucan ABC transporter ATP-binding protein/ permease; |
11-175 |
5.05e-09 |
|
glucan ABC transporter ATP-binding protein/ permease;
Pssm-ID: 184214 [Multi-domain] Cd Length: 588 Bit Score: 56.51 E-value: 5.05e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 11 NVSFERD--KIILKNINWSLHSGENWVLMGLNGAGKTTLLSLIYGNHWATTGSIEVLGETFGKTNVLALKKRIGLIstav 88
Cdd:PRK13657 339 DVSFSYDnsRQGVEDVSFEAKPGQTVAIVGPTGAGKSTLINLLQRVFDPQSGRILIDGTDIRTVTRASLRRNIAVV---- 414
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 89 qsqFPEHHL-----AQYIVLsGKfgtigihNDFEKNDLNEAIG-------LLKKLGG-DELVNKPYRVLSQGQRQLVLIA 155
Cdd:PRK13657 415 ---FQDAGLfnrsiEDNIRV-GR-------PDATDEEMRAAAEraqahdfIERKPDGyDTVVGERGRQLSGGERQRLAIA 483
|
170 180
....*....|....*....|
gi 915796356 156 RALLGKPELLILDEPCNGLD 175
Cdd:PRK13657 484 RALLKDPPILILDEATSALD 503
|
|
| GguA |
NF040905 |
sugar ABC transporter ATP-binding protein; |
21-170 |
5.41e-09 |
|
sugar ABC transporter ATP-binding protein;
Pssm-ID: 468840 [Multi-domain] Cd Length: 500 Bit Score: 56.34 E-value: 5.41e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 21 LKNINWSLHSGENWVLMGLNGAGKTTL---LSLIYGnHWATTGSIEVLGET--FGKTN------VLALKKRIGLIstavq 89
Cdd:NF040905 17 LDDVNLSVREGEIHALCGENGAGKSTLmkvLSGVYP-HGSYEGEILFDGEVcrFKDIRdsealgIVIIHQELALI----- 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 90 sqfPEHHLAQYIVLS---GKFGTIgihnDFEKNdLNEAIGLLKKLGGDELVNKPYRVLSQGQRQLVLIARALLGKPELLI 166
Cdd:NF040905 91 ---PYLSIAENIFLGnerAKRGVI----DWNET-NRRARELLAKVGLDESPDTLVTDIGVGKQQLVEIAKALSKDVKLLI 162
|
....
gi 915796356 167 LDEP 170
Cdd:NF040905 163 LDEP 166
|
|
| ABC_ABC_ChvD |
TIGR03719 |
ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of ... |
6-175 |
6.54e-09 |
|
ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of the ABC transporter ATP-binding cassette, but are found outside the common ABC transporter operon structure that features integral membrane permease proteins and substrate-binding proteins encoded next to the ATP-binding cassette (ABC domain) protein. The member protein ChvD from Agrobacterium tumefaciens was identified as both a candidate to interact with VirB8, based on yeast two-hybrid analysis, and as an apparent regulator of VirG. The general function of this protein family is unknown.
Pssm-ID: 274744 [Multi-domain] Cd Length: 552 Bit Score: 56.10 E-value: 6.54e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 6 VLSMKNVS--FERDKIILKNINWSLHSGENWVLMGLNGAGKTTLLSL-------IYGNHWATTGsIEV--------LGET 68
Cdd:TIGR03719 4 IYTMNRVSkvVPPKKEILKDISLSFFPGAKIGVLGLNGAGKSTLLRImagvdkdFNGEARPQPG-IKVgylpqepqLDPT 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 69 fgKT---NV-LALKKRIGLIS--TAVQSQFPEHHlAQYIVLSGKFGTI-------GIHNdfEKNDLNEAIGLLKKLGGDE 135
Cdd:TIGR03719 83 --KTvreNVeEGVAEIKDALDrfNEISAKYAEPD-ADFDKLAAEQAELqeiidaaDAWD--LDSQLEIAMDALRCPPWDA 157
|
170 180 190 200
....*....|....*....|....*....|....*....|
gi 915796356 136 LVNKpyrvLSQGQRQLVLIARALLGKPELLILDEPCNGLD 175
Cdd:TIGR03719 158 DVTK----LSGGERRRVALCRLLLSKPDMLLLDEPTNHLD 193
|
|
| rim_protein |
TIGR01257 |
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim ... |
31-228 |
7.17e-09 |
|
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim protein) in eukaryotes. It is the member of ABC transporter superfamily. Rim protein is a membrane glycoprotein which is localized in the photoreceptor outer segment discs. Mutation/s in its genetic loci is implicated in the recessive Stargardt's disease. [Transport and binding proteins, Other]
Pssm-ID: 130324 [Multi-domain] Cd Length: 2272 Bit Score: 56.18 E-value: 7.17e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 31 GENWVLMGLNGAGKTTLLSLIYGNHWATTGSIEVLGETFgKTNVLALKKRIGLIST--AVQSQFP-EHHLAQYIVLSGKF 107
Cdd:TIGR01257 1965 GECFGLLGVNGAGKTTTFKMLTGDTTVTSGDATVAGKSI-LTNISDVHQNMGYCPQfdAIDDLLTgREHLYLYARLRGVP 2043
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 108 GtigihNDFEK--NDLNEAIGLlkKLGGDELVNkpyrVLSQGQRQLVLIARALLGKPELLILDEPCNGLDLFSRELLLEQ 185
Cdd:TIGR01257 2044 A-----EEIEKvaNWSIQSLGL--SLYADRLAG----TYSGGNKRKLSTAIALIGCPPLVLLDEPTTGMDPQARRMLWNT 2112
|
170 180 190 200
....*....|....*....|....*....|....*....|...
gi 915796356 186 InkLAQLPNHPTLLFVSHYTEEILPIFKNIMLLKQGEIFAQGT 228
Cdd:TIGR01257 2113 I--VSIIREGRAVVLTSHSMEECEALCTRLAIMVKGAFQCLGT 2153
|
|
| YejF |
COG4172 |
ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites ... |
21-234 |
8.56e-09 |
|
ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites biosynthesis, transport and catabolism];
Pssm-ID: 443332 [Multi-domain] Cd Length: 533 Bit Score: 55.46 E-value: 8.56e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 21 LKNINWSLHSGENWVLMGLNGAGKTTL----LSLIygnhwATTGSIEVLGE---TFGKTNVLALKKRIGLIstaVQSQF- 92
Cdd:COG4172 302 VDGVSLTLRRGETLGLVGESGSGKSTLglalLRLI-----PSEGEIRFDGQdldGLSRRALRPLRRRMQVV---FQDPFg 373
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 93 ---PEHHLAQyIVLSGkfgtIGIHNDfeknDLNEA------IGLLKKLGGD-ELVNK-PYRvLSQGQRQLVLIARALLGK 161
Cdd:COG4172 374 slsPRMTVGQ-IIAEG----LRVHGP----GLSAAerrarvAEALEEVGLDpAARHRyPHE-FSGGQRQRIAIARALILE 443
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 915796356 162 PELLILDEPCNGLDLFSR----ELLLEqINKLAQLpnhpTLLFVSHYTEEILPIFKNIMLLKQGEIFAQGTRDKILT 234
Cdd:COG4172 444 PKLLVLDEPTSALDVSVQaqilDLLRD-LQREHGL----AYLFISHDLAVVRALAHRVMVMKDGKVVEQGPTEQVFD 515
|
|
| PRK10247 |
PRK10247 |
putative ABC transporter ATP-binding protein YbbL; Provisional |
1-208 |
9.24e-09 |
|
putative ABC transporter ATP-binding protein YbbL; Provisional
Pssm-ID: 182331 [Multi-domain] Cd Length: 225 Bit Score: 54.33 E-value: 9.24e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 1 MTNNAVLSMKNVSFERD-KIILKNINWSLHSGENWVLMGLNGAGKTTLLSLIYGNHWATTGSIevlgeTFGKTNVLALKk 79
Cdd:PRK10247 2 QENSPLLQLQNVGYLAGdAKILNNISFSLRAGEFKLITGPSGCGKSTLLKIVASLISPTSGTL-----LFEGEDISTLK- 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 80 riglistavqsqfPE------HHLAQYIVLSGKfgTI--------GIHNDfeKNDLNEAIGLLKKLG-GDELVNKPYRVL 144
Cdd:PRK10247 76 -------------PEiyrqqvSYCAQTPTLFGD--TVydnlifpwQIRNQ--QPDPAIFLDDLERFAlPDTILTKNIAEL 138
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 915796356 145 SQGQRQLVLIARALLGKPELLILDEPCNGLDLFSRELLLEQINKLAQLPNhPTLLFVSHYTEEI 208
Cdd:PRK10247 139 SGGEKQRISLIRNLQFMPKVLLLDEITSALDESNKHNVNEIIHRYVREQN-IAVLWVTHDKDEI 201
|
|
| PRK10584 |
PRK10584 |
putative ABC transporter ATP-binding protein YbbA; Provisional |
20-175 |
9.64e-09 |
|
putative ABC transporter ATP-binding protein YbbA; Provisional
Pssm-ID: 182569 [Multi-domain] Cd Length: 228 Bit Score: 54.40 E-value: 9.64e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 20 ILKNINWSLHSGENWVLMGLNGAGKTTLLSLIYGNHWATTGSIEVLGETFGKTNV---LALK-KRIG-------LIST-- 86
Cdd:PRK10584 25 ILTGVELVVKRGETIALIGESGSGKSTLLAILAGLDDGSSGEVSLVGQPLHQMDEearAKLRaKHVGfvfqsfmLIPTln 104
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 87 AVQS-QFPEhhlaqyiVLSGkfgtigihnDFEKNDLNEAIGLLKKLG-GDELVNKPYRvLSQGQRQLVLIARALLGKPEL 164
Cdd:PRK10584 105 ALENvELPA-------LLRG---------ESSRQSRNGAKALLEQLGlGKRLDHLPAQ-LSGGEQQRVALARAFNGRPDV 167
|
170
....*....|.
gi 915796356 165 LILDEPCNGLD 175
Cdd:PRK10584 168 LFADEPTGNLD 178
|
|
| PLN03073 |
PLN03073 |
ABC transporter F family; Provisional |
19-184 |
1.70e-08 |
|
ABC transporter F family; Provisional
Pssm-ID: 215558 [Multi-domain] Cd Length: 718 Bit Score: 54.87 E-value: 1.70e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 19 IILKNINWSLHSGENWVLMGLNGAGKTTLLSLIYGNHWATTGSI----EVLGETFGKTNV--LALKKRIGLISTAVQSQF 92
Cdd:PLN03073 523 LLFKNLNFGIDLDSRIAMVGPNGIGKSTILKLISGELQPSSGTVfrsaKVRMAVFSQHHVdgLDLSSNPLLYMMRCFPGV 602
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 93 PEHHLAQYIvlsGKFGTIGihndfekndlneaigllkklggdELVNKPYRVLSQGQRQLVLIARALLGKPELLILDEPCN 172
Cdd:PLN03073 603 PEQKLRAHL---GSFGVTG-----------------------NLALQPMYTLSGGQKSRVAFAKITFKKPHILLLDEPSN 656
|
170
....*....|..
gi 915796356 173 GLDLFSRELLLE 184
Cdd:PLN03073 657 HLDLDAVEALIQ 668
|
|
| 40850658_otr |
NF000106 |
oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit; |
110-235 |
3.94e-08 |
|
oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit;
Pssm-ID: 411078 [Multi-domain] Cd Length: 351 Bit Score: 53.20 E-value: 3.94e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 110 IGIHNDFEKNDLN-EAIGLLKKLGGDELVNKPYRVLSQGQRQLVLIARALLGKPELLILDEPCNGLDLFSRELLLEQINK 188
Cdd:NF000106 110 IGR*LDLSRKDARaRADELLERFSLTEAAGRAAAKYSGGMRRRLDLAASMIGRPAVLYLDEPTTGLDPRTRNEVWDEVRS 189
|
90 100 110 120
....*....|....*....|....*....|....*....|....*..
gi 915796356 189 LAQlpNHPTLLFVSHYTEEILPIFKNIMLLKQGEIFAQGTRDKILTE 235
Cdd:NF000106 190 MVR--DGATVLLTTQYMEEAEQLAHELTVIDRGRVIADGKVDELKTK 234
|
|
| PRK10636 |
PRK10636 |
putative ABC transporter ATP-binding protein; Provisional |
18-224 |
4.23e-08 |
|
putative ABC transporter ATP-binding protein; Provisional
Pssm-ID: 236729 [Multi-domain] Cd Length: 638 Bit Score: 53.64 E-value: 4.23e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 18 KIILKNINWSLHSGENWVLMGLNGAGKTTLLSLIYGNHWATTGSIevlgeTFGKTNVLALkkrIGLISTAVQSQFPEHHL 97
Cdd:PRK10636 14 RVLLDNATATINPGQKVGLVGKNGCGKSTLLALLKNEISADGGSY-----TFPGNWQLAW---VNQETPALPQPALEYVI 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 98 ---AQYIVLSGKFGTIGIHND-------FEKNDL-------NEAIGLLKKLG-GDELVNKPYRVLSQGQRQLVLIARALL 159
Cdd:PRK10636 86 dgdREYRQLEAQLHDANERNDghaiatiHGKLDAidawtirSRAASLLHGLGfSNEQLERPVSDFSGGWRMRLNLAQALI 165
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 915796356 160 GKPELLILDEPCNGLDLfSRELLLEQinklaQLPNHP-TLLFVSHYTEEILPIFKNIMLLKQGEIF 224
Cdd:PRK10636 166 CRSDLLLLDEPTNHLDL-DAVIWLEK-----WLKSYQgTLILISHDRDFLDPIVDKIIHIEQQSLF 225
|
|
| PRK13409 |
PRK13409 |
ribosome biogenesis/translation initiation ATPase RLI; |
36-179 |
5.15e-08 |
|
ribosome biogenesis/translation initiation ATPase RLI;
Pssm-ID: 184037 [Multi-domain] Cd Length: 590 Bit Score: 53.27 E-value: 5.15e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 36 LMGLNGAGKTT---LLS--LI--YGNHWATTGSIEVLgETFGKTNVLALKKRI--GLISTAVQSQFPEhhlaqYI--VLS 104
Cdd:PRK13409 104 ILGPNGIGKTTavkILSgeLIpnLGDYEEEPSWDEVL-KRFRGTELQNYFKKLynGEIKVVHKPQYVD-----LIpkVFK 177
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 915796356 105 GKFGTIGIHNDfEKNDLNEaigLLKKLGGDELVNKPYRVLSQGQRQLVLIARALLGKPELLILDEPCNGLDLFSR 179
Cdd:PRK13409 178 GKVRELLKKVD-ERGKLDE---VVERLGLENILDRDISELSGGELQRVAIAAALLRDADFYFFDEPTSYLDIRQR 248
|
|
| PRK11819 |
PRK11819 |
putative ABC transporter ATP-binding protein; Reviewed |
6-175 |
6.55e-08 |
|
putative ABC transporter ATP-binding protein; Reviewed
Pssm-ID: 236992 [Multi-domain] Cd Length: 556 Bit Score: 52.81 E-value: 6.55e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 6 VLSMKNVS--FERDKIILKNINWSLHSGENWVLMGLNGAGKTTLLSL-------IYGNHWATTGsIEV--------LGET 68
Cdd:PRK11819 6 IYTMNRVSkvVPPKKQILKDISLSFFPGAKIGVLGLNGAGKSTLLRImagvdkeFEGEARPAPG-IKVgylpqepqLDPE 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 69 fgKTnVLalkkriGLISTAVQSQFpeHHLAQYIVLSGKFGTigihNDFEKNDLNEAIGLLKK----LGGDELVNK----- 139
Cdd:PRK11819 85 --KT-VR------ENVEEGVAEVK--AALDRFNEIYAAYAE----PDADFDALAAEQGELQEiidaADAWDLDSQleiam 149
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 915796356 140 ----------PYRVLSQGQRQLVLIARALLGKPELLILDEPCNGLD 175
Cdd:PRK11819 150 dalrcppwdaKVTKLSGGERRRVALCRLLLEKPDMLLLDEPTNHLD 195
|
|
| PRK10636 |
PRK10636 |
putative ABC transporter ATP-binding protein; Provisional |
4-203 |
8.46e-08 |
|
putative ABC transporter ATP-binding protein; Provisional
Pssm-ID: 236729 [Multi-domain] Cd Length: 638 Bit Score: 52.86 E-value: 8.46e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 4 NAVLSMKNVSFER-DKIILKNINWSLHSGENWVLMGLNGAGKTTLLSLIYGNHWATTGSIevlgetfgktnvlALKKRIG 82
Cdd:PRK10636 310 NPLLKMEKVSAGYgDRIILDSIKLNLVPGSRIGLLGRNGAGKSTLIKLLAGELAPVSGEI-------------GLAKGIK 376
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 83 LISTAvQSQF--------PEHHLAQYI------VLSGKFGTIGIHndfekndlneaigllkklgGDElVNKPYRVLSQGQ 148
Cdd:PRK10636 377 LGYFA-QHQLeflradesPLQHLARLApqeleqKLRDYLGGFGFQ-------------------GDK-VTEETRRFSGGE 435
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 915796356 149 RQLVLIARALLGKPELLILDEPCNGLDLFSRELLLEqinklAQLPNHPTLLFVSH 203
Cdd:PRK10636 436 KARLVLALIVWQRPNLLLLDEPTNHLDLDMRQALTE-----ALIDFEGALVVVSH 485
|
|
| PRK10982 |
PRK10982 |
galactose/methyl galaxtoside transporter ATP-binding protein; Provisional |
6-223 |
9.74e-08 |
|
galactose/methyl galaxtoside transporter ATP-binding protein; Provisional
Pssm-ID: 182880 [Multi-domain] Cd Length: 491 Bit Score: 52.42 E-value: 9.74e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 6 VLSMKNVSFERDKIIlKNINWSLHSGENWVLMGLNGAGKTTLLSLIYGNHWATTGSIEVLGETFGKTNVL-ALKKRIGLI 84
Cdd:PRK10982 250 ILEVRNLTSLRQPSI-RDVSFDLHKGEILGIAGLVGAKRTDIVETLFGIREKSAGTITLHGKKINNHNANeAINHGFALV 328
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 85 STAVQSQfpehhlAQYIVLSGKFGTIGIHNDFEKNdlneAIGLL--KKLGGD-ELVNKPYRV-----------LSQGQRQ 150
Cdd:PRK10982 329 TEERRST------GIYAYLDIGFNSLISNIRNYKN----KVGLLdnSRMKSDtQWVIDSMRVktpghrtqigsLSGGNQQ 398
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 915796356 151 LVLIARALLGKPELLILDEPCNGLDLFSRELLLEQINKLAQlpNHPTLLFVSHYTEEILPIFKNIMLLKQGEI 223
Cdd:PRK10982 399 KVIIGRWLLTQPEILMLDEPTRGIDVGAKFEIYQLIAELAK--KDKGIIIISSEMPELLGITDRILVMSNGLV 469
|
|
| ATM1 |
COG5265 |
ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components ... |
5-233 |
1.04e-07 |
|
ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 444078 [Multi-domain] Cd Length: 605 Bit Score: 52.51 E-value: 1.04e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 5 AVLSMKNVSF--ERDKIILKNINWSLHSGENWVLMGLNGAGKTTLLSLIYGNHWATTGSIEVLGETFGKTNVLALKKRIG 82
Cdd:COG5265 356 GEVRFENVSFgyDPERPILKGVSFEVPAGKTVAIVGPSGAGKSTLARLLFRFYDVTSGRILIDGQDIRDVTQASLRAAIG 435
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 83 LIstavqsqfPehhlaQYIVLsgkFG-TIGiHN------DFEKNDLNEAI------GLLKKL--GGDELVN----Kpyrv 143
Cdd:COG5265 436 IV--------P-----QDTVL---FNdTIA-YNiaygrpDASEEEVEAAAraaqihDFIESLpdGYDTRVGerglK---- 494
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 144 LSQGQRQLVLIARALLGKPELLILDEPCNGLDLFSRELLLEQINKLAQlpNHPTLLfVSH------YTEEILpifknimL 217
Cdd:COG5265 495 LSGGEKQRVAIARTLLKNPPILIFDEATSALDSRTERAIQAALREVAR--GRTTLV-IAHrlstivDADEIL-------V 564
|
250
....*....|....*.
gi 915796356 218 LKQGEIFAQGTRDKIL 233
Cdd:COG5265 565 LEAGRIVERGTHAELL 580
|
|
| PRK15112 |
PRK15112 |
peptide ABC transporter ATP-binding protein SapF; |
21-233 |
1.47e-07 |
|
peptide ABC transporter ATP-binding protein SapF;
Pssm-ID: 185067 [Multi-domain] Cd Length: 267 Bit Score: 51.33 E-value: 1.47e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 21 LKNINWSLHSGENWVLMGLNGAGKTTLLSLIYGNHWATTGSIEVLGE--TFGKTNVLAlkKRIGLI----STAVQsqfPE 94
Cdd:PRK15112 29 VKPLSFTLREGQTLAIIGENGSGKSTLAKMLAGMIEPTSGELLIDDHplHFGDYSYRS--QRIRMIfqdpSTSLN---PR 103
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 95 HHLAQYIVLSGKFGTIGIHNDFEK--NDLNEAIGLLKklggDELVNKPYrVLSQGQRQLVLIARALLGKPELLILDEPCN 172
Cdd:PRK15112 104 QRISQILDFPLRLNTDLEPEQREKqiIETLRQVGLLP----DHASYYPH-MLAPGQKQRLGLARALILRPKVIIADEALA 178
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 915796356 173 GLDLFSRELLleqINKLAQLPNHPTLLFVshYTEEILPIFKNI----MLLKQGEIFAQGTRDKIL 233
Cdd:PRK15112 179 SLDMSMRSQL---INLMLELQEKQGISYI--YVTQHLGMMKHIsdqvLVMHQGEVVERGSTADVL 238
|
|
| PLN03211 |
PLN03211 |
ABC transporter G-25; Provisional |
16-221 |
1.78e-07 |
|
ABC transporter G-25; Provisional
Pssm-ID: 215634 [Multi-domain] Cd Length: 659 Bit Score: 51.80 E-value: 1.78e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 16 RDKIILKNINWSLHSGENWVLMGLNGAGKTTLLSLIYGNHWAT--TGSIEVLGETFGKTNVlalkKRIGLIsTAVQSQFP 93
Cdd:PLN03211 79 QERTILNGVTGMASPGEILAVLGPSGSGKSTLLNALAGRIQGNnfTGTILANNRKPTKQIL----KRTGFV-TQDDILYP 153
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 94 EHHLAQYIVLSGKFGTIGIHNDFEKNDLNEAI----GLlKKLGGDELVNKPYRVLSQGQRQLVLIARALLGKPELLILDE 169
Cdd:PLN03211 154 HLTVRETLVFCSLLRLPKSLTKQEKILVAESViselGL-TKCENTIIGNSFIRGISGGERKRVSIAHEMLINPSLLILDE 232
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 915796356 170 PCNGLDLFSRELLLEQINKLAQlpNHPTLLFVSHY-TEEILPIFKNIMLLKQG 221
Cdd:PLN03211 233 PTSGLDATAAYRLVLTLGSLAQ--KGKTIVTSMHQpSSRVYQMFDSVLVLSEG 283
|
|
| PRK10261 |
PRK10261 |
glutathione transporter ATP-binding protein; Provisional |
3-232 |
2.34e-07 |
|
glutathione transporter ATP-binding protein; Provisional
Pssm-ID: 182342 [Multi-domain] Cd Length: 623 Bit Score: 51.39 E-value: 2.34e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 3 NNAVLSMK--NVSFERDKI---ILKNINWSLHSGENWVLMGLNGAGKT-TLLSLIYgnhwattgSIEVLGETFGKTNVLA 76
Cdd:PRK10261 9 ARDVLAVEnlNIAFMQEQQkiaAVRNLSFSLQRGETLAIVGESGSGKSvTALALMR--------LLEQAGGLVQCDKMLL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 77 LKKRIGLISTAVQSQFPEHHL----------AQYIVLSGKFgTIGihndfekNDLNEAIGLLKKLGGDELVNKPYRVLSQ 146
Cdd:PRK10261 81 RRRSRQVIELSEQSAAQMRHVrgadmamifqEPMTSLNPVF-TVG-------EQIAESIRLHQGASREEAMVEAKRMLDQ 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 147 -------------------GQRQLVLIARALLGKPELLILDEPCNGLDLFSRELLLEQINKLAQLPNHpTLLFVSHYTEE 207
Cdd:PRK10261 153 vripeaqtilsryphqlsgGMRQRVMIAMALSCRPAVLIADEPTTALDVTIQAQILQLIKVLQKEMSM-GVIFITHDMGV 231
|
250 260
....*....|....*....|....*
gi 915796356 208 ILPIFKNIMLLKQGEIFAQGTRDKI 232
Cdd:PRK10261 232 VAEIADRVLVMYQGEAVETGSVEQI 256
|
|
| ABCC_CFTR1 |
cd03291 |
ATP-binding cassette domain of the cystic fibrosis transmembrane regulator, subfamily C; The ... |
20-228 |
2.48e-07 |
|
ATP-binding cassette domain of the cystic fibrosis transmembrane regulator, subfamily C; The CFTR subfamily domain 1. The cystic fibrosis transmembrane regulator (CFTR), the product of the gene mutated in patients with cystic fibrosis, has adapted the ABC transporter structural motif to form a tightly regulated anion channel at the apical surface of many epithelia. Use of the term assembly of a functional ion channel implies the coming together of subunits, or at least smaller not-yet functional components of the active whole. In fact, on the basis of current knowledge only the CFTR polypeptide itself is required to form an ATP- and protein kinase A-dependent low-conductance chloride channel of the type present in the apical membrane of many epithelial cells. CFTR displays the typical organization (IM-ABC)2 and carries a characteristic hydrophilic R-domain that separates IM1-ABC1 from IM2-ABC2.
Pssm-ID: 213258 [Multi-domain] Cd Length: 282 Bit Score: 50.63 E-value: 2.48e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 20 ILKNINWSLHSGENWVLMGLNGAGKTTLLSLIYGNHWATTGSIevlgetfgktnvlalkKRIGLISTAVQ-SQFPEHHLA 98
Cdd:cd03291 52 VLKNINLKIEKGEMLAITGSTGSGKTSLLMLILGELEPSEGKI----------------KHSGRISFSSQfSWIMPGTIK 115
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 99 QYIVlsgkFGTIgiHNDFEKNDLNEAIGLLKKLGgdELVNKPYRV-------LSQGQRQLVLIARALLGKPELLILDEPC 171
Cdd:cd03291 116 ENII----FGVS--YDEYRYKSVVKACQLEEDIT--KFPEKDNTVlgeggitLSGGQRARISLARAVYKDADLYLLDSPF 187
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 915796356 172 NGLDLFSRELLLEQInkLAQLPNHPTLLFVSHYTEEiLPIFKNIMLLKQGEIFAQGT 228
Cdd:cd03291 188 GYLDVFTEKEIFESC--VCKLMANKTRILVTSKMEH-LKKADKILILHEGSSYFYGT 241
|
|
| oppD |
PRK09473 |
oligopeptide transporter ATP-binding component; Provisional |
2-189 |
2.92e-07 |
|
oligopeptide transporter ATP-binding component; Provisional
Pssm-ID: 181888 [Multi-domain] Cd Length: 330 Bit Score: 50.49 E-value: 2.92e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 2 TNNAVLSMKN--VSF---ERDKIILKNINWSLHSGENWVLMGLNGAGKT----TLLSLIYGNHwATTGSIevlgeTFGKT 72
Cdd:PRK09473 8 QADALLDVKDlrVTFstpDGDVTAVNDLNFSLRAGETLGIVGESGSGKSqtafALMGLLAANG-RIGGSA-----TFNGR 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 73 NVLAL------KKRIGLISTAVQSqfPEHHLAQYIvlsgKFGtigihndfekNDLNEAIGLLKKLGGDELVNKPYRVL-- 144
Cdd:PRK09473 82 EILNLpekelnKLRAEQISMIFQD--PMTSLNPYM----RVG----------EQLMEVLMLHKGMSKAEAFEESVRMLda 145
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 915796356 145 -----------------SQGQRQLVLIARALLGKPELLILDEPCNGLDLFSRELLLEQINKL 189
Cdd:PRK09473 146 vkmpearkrmkmyphefSGGMRQRVMIAMALLCRPKLLIADEPTTALDVTVQAQIMTLLNEL 207
|
|
| PRK15093 |
PRK15093 |
peptide ABC transporter ATP-binding protein SapD; |
124-234 |
3.36e-07 |
|
peptide ABC transporter ATP-binding protein SapD;
Pssm-ID: 185049 [Multi-domain] Cd Length: 330 Bit Score: 50.57 E-value: 3.36e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 124 AIGLLKKLG----GDELVNKPYRvLSQGQRQLVLIARALLGKPELLILDEPCNGLDLFSRELLLEQINKLAQlPNHPTLL 199
Cdd:PRK15093 136 AIELLHRVGikdhKDAMRSFPYE-LTEGECQKVMIAIALANQPRLLIADEPTNAMEPTTQAQIFRLLTRLNQ-NNNTTIL 213
|
90 100 110
....*....|....*....|....*....|....*
gi 915796356 200 FVSHYTEEILPIFKNIMLLKQGEIFAQGTRDKILT 234
Cdd:PRK15093 214 LISHDLQMLSQWADKINVLYCGQTVETAPSKELVT 248
|
|
| NupO |
COG3845 |
ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and ... |
6-185 |
4.77e-07 |
|
ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and metabolism];
Pssm-ID: 443055 [Multi-domain] Cd Length: 504 Bit Score: 50.41 E-value: 4.77e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 6 VLSMKNVSF--ERDKIILKNINWSLHSGEnwVL--MGLNGAGKTTLLSLIYGNHWATTGSIEVLGETFGKTNVLAL-KKR 80
Cdd:COG3845 257 VLEVENLSVrdDRGVPALKDVSLEVRAGE--ILgiAGVAGNGQSELAEALAGLRPPASGSIRLDGEDITGLSPRERrRLG 334
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 81 IGLIstavqsqfPE--HH--------LAQYIVL----SGKFGTIGIHNdfeKNDLNE-AIGLLK----KLGGDELvnkPY 141
Cdd:COG3845 335 VAYI--------PEdrLGrglvpdmsVAENLILgryrRPPFSRGGFLD---RKAIRAfAEELIEefdvRTPGPDT---PA 400
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 915796356 142 RVLSQGQRQLVLIARALLGKPELLILDEPCNGLDL----FSRELLLEQ 185
Cdd:COG3845 401 RSLSGGNQQKVILARELSRDPKLLIAAQPTRGLDVgaieFIHQRLLEL 448
|
|
| LptB |
COG1137 |
ABC-type lipopolysaccharide export system, ATPase component [Cell wall/membrane/envelope ... |
16-233 |
6.00e-07 |
|
ABC-type lipopolysaccharide export system, ATPase component [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440752 [Multi-domain] Cd Length: 240 Bit Score: 49.26 E-value: 6.00e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 16 RDKIILKNINWSLHSGEnwV--LMGLNGAGKTTLLSLIYGNHWATTGSIevlgeTFGKTNV--LALKKR----IGlista 87
Cdd:COG1137 14 GKRTVVKDVSLEVNQGE--IvgLLGPNGAGKTTTFYMIVGLVKPDSGRI-----FLDGEDIthLPMHKRarlgIG----- 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 88 vqsqfpehHLAQ--------------YIVLSgkfgTIGIHNDFEKNDLNEaigLLKKLGGDELVNKPYRVLSQGQRQLVL 153
Cdd:COG1137 82 --------YLPQeasifrkltvedniLAVLE----LRKLSKKEREERLEE---LLEEFGITHLRKSKAYSLSGGERRRVE 146
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 154 IARALLGKPELLILDEPCNGLDLFSRELLLEQINKLAQ-----LpnhptllfVS-HYTEEILPIFKNIMLLKQGEIFAQG 227
Cdd:COG1137 147 IARALATNPKFILLDEPFAGVDPIAVADIQKIIRHLKErgigvL--------ITdHNVRETLGICDRAYIISEGKVLAEG 218
|
....*.
gi 915796356 228 TRDKIL 233
Cdd:COG1137 219 TPEEIL 224
|
|
| AbcC |
COG1135 |
ABC-type methionine transport system, ATPase component [Amino acid transport and metabolism]; |
10-188 |
8.71e-07 |
|
ABC-type methionine transport system, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 440750 [Multi-domain] Cd Length: 339 Bit Score: 49.31 E-value: 8.71e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 10 KNVS--FERDK---IILKNINWSLHSGENWVLMGLNGAGKTTLLSLIYGNHWATTGSIEVLGE---TFGKTNVLALKKRI 81
Cdd:COG1135 5 ENLSktFPTKGgpvTALDDVSLTIEKGEIFGIIGYSGAGKSTLIRCINLLERPTSGSVLVDGVdltALSERELRAARRKI 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 82 GLIStavQsQFpehHLaqyivLSGK--FGTIGI---HNDFEKNDLNEAIG-LLkklggdELV-------NKPyRVLSQGQ 148
Cdd:COG1135 85 GMIF---Q-HF---NL-----LSSRtvAENVALpleIAGVPKAEIRKRVAeLL------ELVglsdkadAYP-SQLSGGQ 145
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 915796356 149 RQLVLIARALLGKPELLILDEPCNGLD-------LfsrELLLEqINK 188
Cdd:COG1135 146 KQRVGIARALANNPKVLLCDEATSALDpettrsiL---DLLKD-INR 188
|
|
| PRK14243 |
PRK14243 |
phosphate transporter ATP-binding protein; Provisional |
144-203 |
9.89e-07 |
|
phosphate transporter ATP-binding protein; Provisional
Pssm-ID: 184588 [Multi-domain] Cd Length: 264 Bit Score: 48.62 E-value: 9.89e-07
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 144 LSQGQRQLVLIARALLGKPELLILDEPCNGLDLFSrELLLEQInkLAQLPNHPTLLFVSH 203
Cdd:PRK14243 152 LSGGQQQRLCIARAIAVQPEVILMDEPCSALDPIS-TLRIEEL--MHELKEQYTIIIVTH 208
|
|
| PLN03232 |
PLN03232 |
ABC transporter C family member; Provisional |
20-236 |
1.03e-06 |
|
ABC transporter C family member; Provisional
Pssm-ID: 215640 [Multi-domain] Cd Length: 1495 Bit Score: 49.59 E-value: 1.03e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 20 ILKNINWSLHSGENWVLMGLNGAGKTTLLSLIYGNHWATTGSIEVLGETFGKTNVLALKKRIGLIStavqsQFPehhlaq 99
Cdd:PLN03232 1251 VLHGLSFFVSPSEKVGVVGRTGAGKSSMLNALFRIVELEKGRIMIDDCDVAKFGLTDLRRVLSIIP-----QSP------ 1319
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 100 yIVLSG--KFGT--IGIHND------FEKNDLNEAIGLlKKLGGDELVNKPYRVLSQGQRQLVLIARALLGKPELLILDE 169
Cdd:PLN03232 1320 -VLFSGtvRFNIdpFSEHNDadlweaLERAHIKDVIDR-NPFGLDAEVSEGGENFSVGQRQLLSLARALLRRSKILVLDE 1397
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 915796356 170 PCNGLDLFSRELLLEQINKLAQlpnHPTLLFVSHYTEEILPIFKnIMLLKQGEIFAQGTRDKILTEN 236
Cdd:PLN03232 1398 ATASVDVRTDSLIQRTIREEFK---SCTMLVIAHRLNTIIDCDK-ILVLSSGQVLEYDSPQELLSRD 1460
|
|
| ABC_ABC_ChvD |
TIGR03719 |
ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of ... |
4-175 |
1.39e-06 |
|
ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of the ABC transporter ATP-binding cassette, but are found outside the common ABC transporter operon structure that features integral membrane permease proteins and substrate-binding proteins encoded next to the ATP-binding cassette (ABC domain) protein. The member protein ChvD from Agrobacterium tumefaciens was identified as both a candidate to interact with VirB8, based on yeast two-hybrid analysis, and as an apparent regulator of VirG. The general function of this protein family is unknown.
Pssm-ID: 274744 [Multi-domain] Cd Length: 552 Bit Score: 48.78 E-value: 1.39e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 4 NAVLSMKNVS--FErDKIILKNINWSLHSGENWVLMGLNGAGKTTLLSLIYGNHWATTGSIEVlGETFgktnvlalkkRI 81
Cdd:TIGR03719 320 DKVIEAENLTkaFG-DKLLIDDLSFKLPPGGIVGVIGPNGAGKSTLFRMITGQEQPDSGTIEI-GETV----------KL 387
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 82 GLISTAVQSQFPEHHLAQYIvlSGKFGTIGIhNDFEKNDlNEAIGLLKKLGGDElvNKPYRVLSQGQRQLVLIARALLGK 161
Cdd:TIGR03719 388 AYVDQSRDALDPNKTVWEEI--SGGLDIIKL-GKREIPS-RAYVGRFNFKGSDQ--QKKVGQLSGGERNRVHLAKTLKSG 461
|
170
....*....|....
gi 915796356 162 PELLILDEPCNGLD 175
Cdd:TIGR03719 462 GNVLLLDEPTNDLD 475
|
|
| PRK13543 |
PRK13543 |
heme ABC exporter ATP-binding protein CcmA; |
1-176 |
1.72e-06 |
|
heme ABC exporter ATP-binding protein CcmA;
Pssm-ID: 184129 [Multi-domain] Cd Length: 214 Bit Score: 47.54 E-value: 1.72e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 1 MTNNAVLSMKNVSFERDKI-ILKNINWSLHSGENWVLMGLNGAGKTTLLSLIYGNHWATTGSIEVLGE---TFGKTNVLA 76
Cdd:PRK13543 6 HTAPPLLAAHALAFSRNEEpVFGPLDFHVDAGEALLVQGDNGAGKTTLLRVLAGLLHVESGQIQIDGKtatRGDRSRFMA 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 77 LKKRIGLISTAVQSQFPEHHLAqyivlsgkfgtiGIHNDFEKNDLNEAIGLLKKLG-GDELVnkpyRVLSQGQRQLVLIA 155
Cdd:PRK13543 86 YLGHLPGLKADLSTLENLHFLC------------GLHGRRAKQMPGSALAIVGLAGyEDTLV----RQLSAGQKKRLALA 149
|
170 180
....*....|....*....|.
gi 915796356 156 RALLGKPELLILDEPCNGLDL 176
Cdd:PRK13543 150 RLWLSPAPLWLLDEPYANLDL 170
|
|
| metN |
PRK11153 |
DL-methionine transporter ATP-binding subunit; Provisional |
21-228 |
1.93e-06 |
|
DL-methionine transporter ATP-binding subunit; Provisional
Pssm-ID: 236863 [Multi-domain] Cd Length: 343 Bit Score: 48.26 E-value: 1.93e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 21 LKNINWSLHSGENWVLMGLNGAGKTTLLSLIYGNHWATTGSIEVLGE---TFGKTNVLALKKRIGLIstavqsqFPEHHL 97
Cdd:PRK11153 21 LNNVSLHIPAGEIFGVIGASGAGKSTLIRCINLLERPTSGRVLVDGQdltALSEKELRKARRQIGMI-------FQHFNL 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 98 aqyivLSGK--FGTI-------GIHNDFEKNDLNEaigLLKKLGGDELVNKPYRVLSQGQRQLVLIARALLGKPELLILD 168
Cdd:PRK11153 94 -----LSSRtvFDNValplelaGTPKAEIKARVTE---LLELVGLSDKADRYPAQLSGGQKQRVAIARALASNPKVLLCD 165
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 915796356 169 EPCNGLD-------LfsreLLLEQINKLAQLpnhpTLLFVSHYTEEILPIFKNIMLLKQGEIFAQGT 228
Cdd:PRK11153 166 EATSALDpattrsiL----ELLKDINRELGL----TIVLITHEMDVVKRICDRVAVIDAGRLVEQGT 224
|
|
| AppF |
COG4608 |
ABC-type oligopeptide transport system, ATPase component [Amino acid transport and metabolism]; ... |
144-203 |
1.94e-06 |
|
ABC-type oligopeptide transport system, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 443658 [Multi-domain] Cd Length: 329 Bit Score: 48.19 E-value: 1.94e-06
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 915796356 144 LSQGQRQLVLIARALLGKPELLILDEPCNGLDLfSREL----LLEQINKLAQLpnhpTLLFVSH 203
Cdd:COG4608 158 FSGGQRQRIGIARALALNPKLIVCDEPVSALDV-SIQAqvlnLLEDLQDELGL----TYLFISH 216
|
|
| sufC |
PRK09580 |
cysteine desulfurase ATPase component; Reviewed |
6-227 |
1.96e-06 |
|
cysteine desulfurase ATPase component; Reviewed
Pssm-ID: 181965 [Multi-domain] Cd Length: 248 Bit Score: 47.86 E-value: 1.96e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 6 VLSMKN--VSFErDKIILKNINWSLHSGENWVLMGLNGAGKTTLLSLIYG--NHWATTGSIevlgeTFGKTNVLAL--KK 79
Cdd:PRK09580 1 MLSIKDlhVSVE-DKAILRGLNLEVRPGEVHAIMGPNGSGKSTLSATLAGreDYEVTGGTV-----EFKGKDLLELspED 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 80 RIGL-ISTAVQSQFPEHHLAQYIVLSGKFGTIGIHNDFEKND-------LNEAIGLLKKlgGDELVNKPYRV-LSQGQRQ 150
Cdd:PRK09580 75 RAGEgIFMAFQYPVEIPGVSNQFFLQTALNAVRSYRGQEPLDrfdfqdlMEEKIALLKM--PEDLLTRSVNVgFSGGEKK 152
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 915796356 151 LVLIARALLGKPELLILDEPCNGLDLFSRELLLEQINKLAQlpNHPTLLFVSHYtEEILPIFK--NIMLLKQGEIFAQG 227
Cdd:PRK09580 153 RNDILQMAVLEPELCILDESDSGLDIDALKIVADGVNSLRD--GKRSFIIVTHY-QRILDYIKpdYVHVLYQGRIVKSG 228
|
|
| PTZ00265 |
PTZ00265 |
multidrug resistance protein (mdr1); Provisional |
140-248 |
3.04e-06 |
|
multidrug resistance protein (mdr1); Provisional
Pssm-ID: 240339 [Multi-domain] Cd Length: 1466 Bit Score: 48.10 E-value: 3.04e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 140 PY-RVLSQGQRQLVLIARALLGKPELLILDEPCNGLDLFSRELLLEQINKLAQLPNHpTLLFVSHYTEEI-----LPIFK 213
Cdd:PTZ00265 1354 PYgKSLSGGQKQRIAIARALLREPKILLLDEATSSLDSNSEKLIEKTIVDIKDKADK-TIITIAHRIASIkrsdkIVVFN 1432
|
90 100 110
....*....|....*....|....*....|....*.
gi 915796356 214 NIMllKQGE-IFAQGTRDKILTenVLSKFYPKPIKI 248
Cdd:PTZ00265 1433 NPD--RTGSfVQAHGTHEELLS--VQDGVYKKYVKL 1464
|
|
| PLN03073 |
PLN03073 |
ABC transporter F family; Provisional |
135-218 |
3.50e-06 |
|
ABC transporter F family; Provisional
Pssm-ID: 215558 [Multi-domain] Cd Length: 718 Bit Score: 47.93 E-value: 3.50e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 135 ELVNKPYRVLSQGQRQLVLIARALLGKPELLILDEPCNGLDLFSrELLLEqiNKLAQLPNhpTLLFVSHYTEEILPIFKN 214
Cdd:PLN03073 336 EMQVKATKTFSGGWRMRIALARALFIEPDLLLLDEPTNHLDLHA-VLWLE--TYLLKWPK--TFIVVSHAREFLNTVVTD 410
|
....
gi 915796356 215 IMLL 218
Cdd:PLN03073 411 ILHL 414
|
|
| ABCC_SUR1_N |
cd03290 |
ATP-binding cassette domain of the sulfonylurea receptor, subfamily C; The SUR domain 1. The ... |
21-221 |
3.63e-06 |
|
ATP-binding cassette domain of the sulfonylurea receptor, subfamily C; The SUR domain 1. The sulfonylurea receptor SUR is an ATP transporter of the ABCC/MRP family with tandem ATPase binding domains. Unlike other ABC proteins, it has no intrinsic transport function, neither active nor passive, but associates with the potassium channel proteins Kir6.1 or Kir6.2 to form the ATP-sensitive potassium (K(ATP)) channel. Within the channel complex, SUR serves as a regulatory subunit that fine-tunes the gating of Kir6.x in response to alterations in cellular metabolism. It constitutes a major pharmaceutical target as it binds numerous drugs, K(ATP) channel openers and blockers, capable of up- or down-regulating channel activity.
Pssm-ID: 213257 [Multi-domain] Cd Length: 218 Bit Score: 46.56 E-value: 3.63e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 21 LKNINWSLHSGENWVLMGLNGAGKTTLLSLIYGNHWATTGSIEVLGETFGKTNVLALKKRiGLISTAVQSQFP---EHHL 97
Cdd:cd03290 17 LSNINIRIPTGQLTMIVGQVGCGKSSLLLAILGEMQTLEGKVHWSNKNESEPSFEATRSR-NRYSVAYAAQKPwllNATV 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 98 AQYIVLSGKFGTIGIHNDFEKNDLNEAIGLLKkLGGDELVNKPYRVLSQGQRQLVLIARALLGKPELLILDEPCNGLDL- 176
Cdd:cd03290 96 EENITFGSPFNKQRYKAVTDACSLQPDIDLLP-FGDQTEIGERGINLSGGQRQRICVARALYQNTNIVFLDDPFSALDIh 174
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
gi 915796356 177 FSRELLLEQINKLAQlPNHPTLLFVSHYTeEILPIFKNIMLLKQG 221
Cdd:cd03290 175 LSDHLMQEGILKFLQ-DDKRTLVLVTHKL-QYLPHADWIIAMKDG 217
|
|
| PRK15079 |
PRK15079 |
oligopeptide ABC transporter ATP-binding protein OppF; Provisional |
24-203 |
3.65e-06 |
|
oligopeptide ABC transporter ATP-binding protein OppF; Provisional
Pssm-ID: 185037 [Multi-domain] Cd Length: 331 Bit Score: 47.39 E-value: 3.65e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 24 INWSLHSGENWVLMGLNGAGKTTLLSLIYGNHWATTGSIEVLGETFGKTN---VLALKKRIGLIStavqsQFPehhLAQy 100
Cdd:PRK15079 40 VTLRLYEGETLGVVGESGCGKSTFARAIIGLVKATDGEVAWLGKDLLGMKddeWRAVRSDIQMIF-----QDP---LAS- 110
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 101 ivLSGKFgTIG---------IHNDFEKNDLNEAI-GLLKKLG-GDELVNKPYRVLSQGQRQLVLIARALLGKPELLILDE 169
Cdd:PRK15079 111 --LNPRM-TIGeiiaeplrtYHPKLSRQEVKDRVkAMMLKVGlLPNLINRYPHEFSGGQCQRIGIARALILEPKLIICDE 187
|
170 180 190
....*....|....*....|....*....|....*..
gi 915796356 170 PCNGLDLFSREL---LLEQINKLAQLpnhpTLLFVSH 203
Cdd:PRK15079 188 PVSALDVSIQAQvvnLLQQLQREMGL----SLIFIAH 220
|
|
| PRK11147 |
PRK11147 |
ABC transporter ATPase component; Reviewed |
5-203 |
5.25e-06 |
|
ABC transporter ATPase component; Reviewed
Pssm-ID: 236861 [Multi-domain] Cd Length: 635 Bit Score: 47.25 E-value: 5.25e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 5 AVLSMKN--VSFErDKIILKNINWSLHSGENWVLMGLNGAGKTTLLSLIYGNHWATTGSI-----------------EVL 65
Cdd:PRK11147 2 SLISIHGawLSFS-DAPLLDNAELHIEDNERVCLVGRNGAGKSTLMKILNGEVLLDDGRIiyeqdlivarlqqdpprNVE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 66 GETF-----GKTNVLALKKRIGLISTAVQSQFPEHHLAQyivLSGKFGTIGIHN--DFEkNDLNEAIGLLKkLGGDELVN 138
Cdd:PRK11147 81 GTVYdfvaeGIEEQAEYLKRYHDISHLVETDPSEKNLNE---LAKLQEQLDHHNlwQLE-NRINEVLAQLG-LDPDAALS 155
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 915796356 139 KpyrvLSQG-QRQLVLiARALLGKPELLILDEPCNGLDLFSRElLLEQINKLAQlpnhPTLLFVSH 203
Cdd:PRK11147 156 S----LSGGwLRKAAL-GRALVSNPDVLLLDEPTNHLDIETIE-WLEGFLKTFQ----GSIIFISH 211
|
|
| ABCC_SUR2 |
cd03288 |
ATP-binding cassette domain 2 of the sulfonylurea receptor SUR; The SUR domain 2. The ... |
18-235 |
7.22e-06 |
|
ATP-binding cassette domain 2 of the sulfonylurea receptor SUR; The SUR domain 2. The sulfonylurea receptor SUR is an ATP binding cassette (ABC) protein of the ABCC/MRP family. Unlike other ABC proteins, it has no intrinsic transport function, neither active nor passive, but associates with the potassium channel proteins Kir6.1 or Kir6.2 to form the ATP-sensitive potassium (K(ATP)) channel. Within the channel complex, SUR serves as a regulatory subunit that fine-tunes the gating of Kir6.x in response to alterations in cellular metabolism. It constitutes a major pharmaceutical target as it binds numerous drugs, K(ATP) channel openers and blockers, capable of up- or down-regulating channel activity.
Pssm-ID: 213255 [Multi-domain] Cd Length: 257 Bit Score: 46.06 E-value: 7.22e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 18 KIILKNINWSLHSGENWVLMGLNGAGKTTLlSLIYGNHWAT-TGSIEVLGETFGKTNVLALKKRIGLIstavqsqfpehh 96
Cdd:cd03288 34 KPVLKHVKAYIKPGQKVGICGRTGSGKSSL-SLAFFRMVDIfDGKIVIDGIDISKLPLHTLRSRLSII------------ 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 97 LAQYIVLSGkfgTIGIHNDFEK----NDLNEA--IGLLKKL------GGDELVNKPYRVLSQGQRQLVLIARALLGKPEL 164
Cdd:cd03288 101 LQDPILFSG---SIRFNLDPECkctdDRLWEAleIAQLKNMvkslpgGLDAVVTEGGENFSVGQRQLFCLARAFVRKSSI 177
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 915796356 165 LILDEPCNGLDLfSRELLLEQINKLAQLPNhpTLLFVSHYTEEILPIfKNIMLLKQGEIFAQGTRDKILTE 235
Cdd:cd03288 178 LIMDEATASIDM-ATENILQKVVMTAFADR--TVVTIAHRVSTILDA-DLVLVLSRGILVECDTPENLLAQ 244
|
|
| 3a01205 |
TIGR00956 |
Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other] |
20-234 |
1.19e-05 |
|
Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other]
Pssm-ID: 273362 [Multi-domain] Cd Length: 1394 Bit Score: 46.26 E-value: 1.19e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 20 ILKNINWSLHSGENWVLMGLNGAGKTTLL----SLIYGNHWATTGSIEVLGetFGKTNVLALKKRIGLISTAVQSQFPEH 95
Cdd:TIGR00956 76 ILKPMDGLIKPGELTVVLGRPGSGCSTLLktiaSNTDGFHIGVEGVITYDG--ITPEEIKKHYRGDVVYNAETDVHFPHL 153
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 96 HLAQYIVLSGKFGTI-----GIHNDFEKNDLNEAIglLKKLG---------GDELVnkpyRVLSQGQRQLVLIARALLGK 161
Cdd:TIGR00956 154 TVGETLDFAARCKTPqnrpdGVSREEYAKHIADVY--MATYGlshtrntkvGNDFV----RGVSGGERKRVSIAEASLGG 227
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 915796356 162 PELLILDEPCNGLDlfsRELLLEQINKLAQLPNH-PTLLFVSHY--TEEILPIFKNIMLLKQGEIFAQGTRDKILT 234
Cdd:TIGR00956 228 AKIQCWDNATRGLD---SATALEFIRALKTSANIlDTTPLVAIYqcSQDAYELFDKVIVLYEGYQIYFGPADKAKQ 300
|
|
| PRK10522 |
PRK10522 |
multidrug transporter membrane component/ATP-binding component; Provisional |
7-169 |
1.63e-05 |
|
multidrug transporter membrane component/ATP-binding component; Provisional
Pssm-ID: 236707 [Multi-domain] Cd Length: 547 Bit Score: 45.73 E-value: 1.63e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 7 LSMKNVSF--ERDKIILKNINWSLHSGENWVLMGLNGAGKTTLLSLIYGNHWATTGSIEVLGETFGKTNVLALKKrigLI 84
Cdd:PRK10522 323 LELRNVTFayQDNGFSVGPINLTIKRGELLFLIGGNGSGKSTLAMLLTGLYQPQSGEILLDGKPVTAEQPEDYRK---LF 399
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 85 StAVQSQFpehHLAQYivLSGKFGtigihndFEKNDLNEAIgLLKKLG-GDELVNKPYRV----LSQGQRQLVLIARALL 159
Cdd:PRK10522 400 S-AVFTDF---HLFDQ--LLGPEG-------KPANPALVEK-WLERLKmAHKLELEDGRIsnlkLSKGQKKRLALLLALA 465
|
170
....*....|
gi 915796356 160 GKPELLILDE 169
Cdd:PRK10522 466 EERDILLLDE 475
|
|
| dppF |
PRK11308 |
dipeptide transporter ATP-binding subunit; Provisional |
145-203 |
1.79e-05 |
|
dipeptide transporter ATP-binding subunit; Provisional
Pssm-ID: 236898 [Multi-domain] Cd Length: 327 Bit Score: 45.34 E-value: 1.79e-05
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 915796356 145 SQGQRQLVLIARALLGKPELLILDEPCNGLDLFSRELLLeqiNKLAQLPNHPTL--LFVSH 203
Cdd:PRK11308 156 SGGQRQRIAIARALMLDPDVVVADEPVSALDVSVQAQVL---NLMMDLQQELGLsyVFISH 213
|
|
| phnK |
PRK11701 |
phosphonate C-P lyase system protein PhnK; Provisional |
1-233 |
1.82e-05 |
|
phosphonate C-P lyase system protein PhnK; Provisional
Pssm-ID: 183280 [Multi-domain] Cd Length: 258 Bit Score: 44.92 E-value: 1.82e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 1 MTNNAVLSMKNVS-FERDKIILKNINWSLHSGENWVLMGLNGAGKTTLLSLIYGNHWATTGSIEVLGETFGKTNVLAL-- 77
Cdd:PRK11701 1 MMDQPLLSVRGLTkLYGPRKGCRDVSFDLYPGEVLGIVGESGSGKTTLLNALSARLAPDAGEVHYRMRDGQLRDLYALse 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 78 KKRIGLIST--AVQSQFPEHHLAQYIVLSGKFG----TIGIHNDFEKNDlnEAIGLLKK--LGGDELVNKPyRVLSQGQR 149
Cdd:PRK11701 81 AERRRLLRTewGFVHQHPRDGLRMQVSAGGNIGerlmAVGARHYGDIRA--TAGDWLERveIDAARIDDLP-TTFSGGMQ 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 150 QLVLIARALLGKPELLILDEPCNGLDLFSRELLLEQINKL-AQLpnHPTLLFVSH--YTEEILPifKNIMLLKQGEIFAQ 226
Cdd:PRK11701 158 QRLQIARNLVTHPRLVFMDEPTGGLDVSVQARLLDLLRGLvREL--GLAVVIVTHdlAVARLLA--HRLLVMKQGRVVES 233
|
....*..
gi 915796356 227 GTRDKIL 233
Cdd:PRK11701 234 GLTDQVL 240
|
|
| PLN03140 |
PLN03140 |
ABC transporter G family member; Provisional |
133-234 |
2.66e-05 |
|
ABC transporter G family member; Provisional
Pssm-ID: 215599 [Multi-domain] Cd Length: 1470 Bit Score: 45.22 E-value: 2.66e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 133 GDELVnkpyRVLSQGQRQLVLIARALLGKPELLILDEPCNGLDLFSRELLLEQINKLAQLPNHPTLLFVSHYTEEILPIF 212
Cdd:PLN03140 330 GDEMI----RGISGGQKKRVTTGEMIVGPTKTLFMDEISTGLDSSTTYQIVKCLQQIVHLTEATVLMSLLQPAPETFDLF 405
|
90 100
....*....|....*....|..
gi 915796356 213 KNIMLLKQGEIFAQGTRDKILT 234
Cdd:PLN03140 406 DDIILLSEGQIVYQGPRDHILE 427
|
|
| PLN03130 |
PLN03130 |
ABC transporter C family member; Provisional |
20-169 |
3.71e-05 |
|
ABC transporter C family member; Provisional
Pssm-ID: 215595 [Multi-domain] Cd Length: 1622 Bit Score: 44.73 E-value: 3.71e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 20 ILKNINWSLHSGENWVLMGLNGAGKTTLLSLIYGNHWATTGSIEVLGETFGKTNVLALKKRIGLIStavqsQFPehhlaq 99
Cdd:PLN03130 1254 VLHGLSFEISPSEKVGIVGRTGAGKSSMLNALFRIVELERGRILIDGCDISKFGLMDLRKVLGIIP-----QAP------ 1322
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 100 yIVLSG--KFG--TIGIHND------FEKNDLNEAIgLLKKLGGDELVNKPYRVLSQGQRQLVLIARALLGKPELLILDE 169
Cdd:PLN03130 1323 -VLFSGtvRFNldPFNEHNDadlwesLERAHLKDVI-RRNSLGLDAEVSEAGENFSVGQRQLLSLARALLRRSKILVLDE 1400
|
|
| AAA_21 |
pfam13304 |
AAA domain, putative AbiEii toxin, Type IV TA system; Several members are annotated as being ... |
76-203 |
3.87e-05 |
|
AAA domain, putative AbiEii toxin, Type IV TA system; Several members are annotated as being of the abortive phage resistance system, in which case the family would be acting as the toxin for a type IV toxin-antitoxin resistance system.
Pssm-ID: 433102 [Multi-domain] Cd Length: 303 Bit Score: 44.30 E-value: 3.87e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 76 ALKKRIGLISTAVQSQFPEHHLAQYIVLSGKFGTIGIHNDFEKNDLNEAIGLLKKLGGDELVnkPYRVLSQGQRQLVLIA 155
Cdd:pfam13304 171 LAADLALFPDLKELLQRLVRGLKLADLNLSDLGEGIEKSLLVDDRLRERGLILLENGGGGEL--PAFELSDGTKRLLALL 248
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|.
gi 915796356 156 RALL---GKPELLILDEPCNGLDLFSRELLLEQINKLAQlpNHPTLLFVSH 203
Cdd:pfam13304 249 AALLsalPKGGLLLIDEPESGLHPKLLRRLLELLKELSR--NGAQLILTTH 297
|
|
| PRK10261 |
PRK10261 |
glutathione transporter ATP-binding protein; Provisional |
21-253 |
4.74e-05 |
|
glutathione transporter ATP-binding protein; Provisional
Pssm-ID: 182342 [Multi-domain] Cd Length: 623 Bit Score: 44.46 E-value: 4.74e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 21 LKNINWSLHSGENWVLMGLNGAGKTT----LLSLIYgnhwATTGSIEVLGE---TFGKTNVLALKKRIGLISTAVQSQFP 93
Cdd:PRK10261 340 VEKVSFDLWPGETLSLVGESGSGKSTtgraLLRLVE----SQGGEIIFNGQridTLSPGKLQALRRDIQFIFQDPYASLD 415
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 94 EHHLAQYIVLSgkfgTIGIHNDFEKNDLNEAIG-LLKKLG--GDELVNKPYRvLSQGQRQLVLIARALLGKPELLILDEP 170
Cdd:PRK10261 416 PRQTVGDSIME----PLRVHGLLPGKAAAARVAwLLERVGllPEHAWRYPHE-FSGGQRQRICIARALALNPKVIIADEA 490
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 171 CNGLDLFSRELLleqINKLAQLPNH--PTLLFVSHYTEEILPIFKNIMLLKQGEIFAQGTRDKILtENVLSKFYPKPIKI 248
Cdd:PRK10261 491 VSALDVSIRGQI---INLLLDLQRDfgIAYLFISHDMAVVERISHRVAVMYLGQIVEIGPRRAVF-ENPQHPYTRKLMAA 566
|
....*
gi 915796356 249 FPVTN 253
Cdd:PRK10261 567 VPVAD 571
|
|
| ABC_Class2 |
cd03227 |
ATP-binding cassette domain of non-transporter proteins; ABC-type Class 2 contains systems ... |
144-220 |
6.56e-05 |
|
ATP-binding cassette domain of non-transporter proteins; ABC-type Class 2 contains systems involved in cellular processes other than transport. These families are characterized by the fact that the ABC subunit is made up of duplicated, fused ABC modules (ABC2). No known transmembrane proteins or domains are associated with these proteins.
Pssm-ID: 213194 [Multi-domain] Cd Length: 162 Bit Score: 42.35 E-value: 6.56e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 144 LSQGQRQLVLIARAL---LGKPE-LLILDEPCNGLDLFSRELLLEQINKLAQlpNHPTLLFVSHYTEEILPIFKNIMLLK 219
Cdd:cd03227 78 LSGGEKELSALALILalaSLKPRpLYILDEIDRGLDPRDGQALAEAILEHLV--KGAQVIVITHLPELAELADKLIHIKK 155
|
.
gi 915796356 220 Q 220
Cdd:cd03227 156 V 156
|
|
| nikD |
PRK10418 |
nickel transporter ATP-binding protein NikD; Provisional |
3-203 |
8.46e-05 |
|
nickel transporter ATP-binding protein NikD; Provisional
Pssm-ID: 236688 [Multi-domain] Cd Length: 254 Bit Score: 42.76 E-value: 8.46e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 3 NNAVLSMKNVSFERDKIILKNINWSLHSGENWVLMGLNGAGKT----TLLSLIYGNHWATTGSIEVLGETfgktnVLALK 78
Cdd:PRK10418 1 MPQQIELRNIALQAAQPLVHGVSLTLQRGRVLALVGGSGSGKSltcaAALGILPAGVRQTAGRVLLDGKP-----VAPCA 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 79 KRIGLISTAVQ---SQF-PEHHLAQYIVLSGKfgTIGIHNDfekndLNEAIGLLKKLGGDElvnkPYRVL-------SQG 147
Cdd:PRK10418 76 LRGRKIATIMQnprSAFnPLHTMHTHARETCL--ALGKPAD-----DATLTAALEAVGLEN----AARVLklypfemSGG 144
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 915796356 148 QRQLVLIARALLGKPELLILDEPCNGLDLFSRELLLEQINKLAQlPNHPTLLFVSH 203
Cdd:PRK10418 145 MLQRMMIALALLCEAPFIIADEPTTDLDVVAQARILDLLESIVQ-KRALGMLLVTH 199
|
|
| ABC2_perm_RbbA |
NF033858 |
ribosome-associated ATPase/putative transporter RbbA; |
36-179 |
1.85e-04 |
|
ribosome-associated ATPase/putative transporter RbbA;
Pssm-ID: 468210 [Multi-domain] Cd Length: 907 Bit Score: 42.42 E-value: 1.85e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 36 LMGLNGAGKTTLLSLIYGNHWATTGSIEVLGETFGKTNVL-ALKKRI-----GL-------ISTAVQSQFpehhlaqyiv 102
Cdd:NF033858 32 LIGPDGVGKSSLLSLIAGARKIQQGRVEVLGGDMADARHRrAVCPRIaympqGLgknlyptLSVFENLDF---------- 101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 103 lsgkFGTIGIHNDFEK----NDLNEAIGLlkklggDELVNKPYRVLSQGQRQ-LVLIArALLGKPELLILDEPCNGLDLF 177
Cdd:NF033858 102 ----FGRLFGQDAAERrrriDELLRATGL------APFADRPAGKLSGGMKQkLGLCC-ALIHDPDLLILDEPTTGVDPL 170
|
..
gi 915796356 178 SR 179
Cdd:NF033858 171 SR 172
|
|
| dppD |
PRK11022 |
dipeptide transporter ATP-binding subunit; Provisional |
124-184 |
1.91e-04 |
|
dipeptide transporter ATP-binding subunit; Provisional
Pssm-ID: 182906 [Multi-domain] Cd Length: 326 Bit Score: 42.04 E-value: 1.91e-04
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 915796356 124 AIGLLKKLG----GDELVNKPYRvLSQGQRQLVLIARALLGKPELLILDEPCNGLDLFSR----ELLLE 184
Cdd:PRK11022 131 AIDLLNQVGipdpASRLDVYPHQ-LSGGMSQRVMIAMAIACRPKLLIADEPTTALDVTIQaqiiELLLE 198
|
|
| GguA |
NF040905 |
sugar ABC transporter ATP-binding protein; |
16-190 |
2.07e-04 |
|
sugar ABC transporter ATP-binding protein;
Pssm-ID: 468840 [Multi-domain] Cd Length: 500 Bit Score: 42.08 E-value: 2.07e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 16 RDKIILKNINWSLHSGENWVLMGLNGAGKTTLLSLIYGNHWAT--TGSIEVLGETFGKTNV-------LAL----KKRIG 82
Cdd:NF040905 271 PERKVVDDVSLNVRRGEIVGIAGLMGAGRTELAMSVFGRSYGRniSGTVFKDGKEVDVSTVsdaidagLAYvtedRKGYG 350
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 83 LIStavqsqfpEHHLAQYIVLS--GKFGTIGIHNDFEknDLNEAIGLLKKL-----GGDELVNKpyrvLSQGQRQLVLIA 155
Cdd:NF040905 351 LNL--------IDDIKRNITLAnlGKVSRRGVIDENE--EIKVAEEYRKKMniktpSVFQKVGN----LSGGNQQKVVLS 416
|
170 180 190
....*....|....*....|....*....|....*
gi 915796356 156 RALLGKPELLILDEPCNGLDLFSRELLLEQINKLA 190
Cdd:NF040905 417 KWLFTDPDVLILDEPTRGIDVGAKYEIYTIINELA 451
|
|
| ABC_Rad50 |
cd03240 |
ATP-binding cassette domain of Rad50; The catalytic domains of Rad50 are similar to the ... |
7-203 |
4.04e-04 |
|
ATP-binding cassette domain of Rad50; The catalytic domains of Rad50 are similar to the ATP-binding cassette of ABC transporters, but are not associated with membrane-spanning domains. The conserved ATP-binding motifs common to Rad50 and the ABC transporter family include the Walker A and Walker B motifs, the Q loop, a histidine residue in the switch region, a D-loop, and a conserved LSGG sequence. This conserved sequence, LSGG, is the most specific and characteristic motif of this family and is thus known as the ABC signature sequence.
Pssm-ID: 213207 [Multi-domain] Cd Length: 204 Bit Score: 40.28 E-value: 4.04e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 7 LSMKNV-SFERDKIIlkninwSLHSGENwVLMGLNGAGKTTLLSLI----YGNHWATTGSIEVLGETFGKTNVLAlkkri 81
Cdd:cd03240 4 LSIRNIrSFHERSEI------EFFSPLT-LIVGQNGAGKTTIIEALkyalTGELPPNSKGGAHDPKLIREGEVRA----- 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 82 glistavqsqfpEHHLAqYIVLSGKfgTIGIHNDFekNDLNEAI----GLLKKLGGDELVNkpyrvLSQGQRQLVLI--- 154
Cdd:cd03240 72 ------------QVKLA-FENANGK--KYTITRSL--AILENVIfchqGESNWPLLDMRGR-----CSGGEKVLASLiir 129
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 915796356 155 ---ARALLGKPELLILDEPCNGLDLFSRELLLEQINKLAQLPNHPTLLFVSH 203
Cdd:cd03240 130 lalAETFGSNCGILALDEPTTNLDEENIEESLAEIIEERKSQKNFQLIVITH 181
|
|
| PvdE |
COG4615 |
ABC-type siderophore export system, fused ATPase and permease components [Inorganic ion ... |
7-169 |
4.09e-04 |
|
ABC-type siderophore export system, fused ATPase and permease components [Inorganic ion transport and metabolism];
Pssm-ID: 443659 [Multi-domain] Cd Length: 547 Bit Score: 41.32 E-value: 4.09e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 7 LSMKNVSF------ERDKIILKNINWSLHSGENWVLMGLNGAGKTTLLSLIYGNHWATTGSIEVLGETFGKTNVLALKKR 80
Cdd:COG4615 328 LELRGVTYrypgedGDEGFTLGPIDLTIRRGELVFIVGGNGSGKSTLAKLLTGLYRPESGEILLDGQPVTADNREAYRQL 407
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 81 IglisTAVqsqFPEHHLaqyivlsgkFGT-IGIHNDFEKNDLNEaigLLKKLGGDELVnkpyRV---------LSQGQRQ 150
Cdd:COG4615 408 F----SAV---FSDFHL---------FDRlLGLDGEADPARARE---LLERLELDHKV----SVedgrfsttdLSQGQRK 464
|
170 180
....*....|....*....|.
gi 915796356 151 -LVLIArALL-GKPeLLILDE 169
Cdd:COG4615 465 rLALLV-ALLeDRP-ILVFDE 483
|
|
| AAA |
smart00382 |
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ... |
30-210 |
5.64e-04 |
|
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.
Pssm-ID: 214640 [Multi-domain] Cd Length: 148 Bit Score: 39.28 E-value: 5.64e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 30 SGENWVLMGLNGAGKTTLLSLIYGNHWATTGSIEVLgetfgktnvlalkkriglistavqsqfpehhlaqyivlsgkfgt 109
Cdd:smart00382 1 PGEVILIVGPPGSGKTTLARALARELGPPGGGVIYI-------------------------------------------- 36
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 110 igihndfeknDLNEAIGLLKKLGGDELVNKPYRVLSQGQRQLVLIARALLGKPELLILDEPCNGLDLFSRELLLE----Q 185
Cdd:smart00382 37 ----------DGEDILEEVLDQLLLIIVGGKKASGSGELRLRLALALARKLKPDVLILDEITSLLDAEQEALLLLleelR 106
|
170 180
....*....|....*....|....*
gi 915796356 186 INKLAQLPNHPTLLFVSHYTEEILP 210
Cdd:smart00382 107 LLLLLKSEKNLTVILTTNDEKDLGP 131
|
|
| PRK11819 |
PRK11819 |
putative ABC transporter ATP-binding protein; Reviewed |
4-175 |
5.88e-04 |
|
putative ABC transporter ATP-binding protein; Reviewed
Pssm-ID: 236992 [Multi-domain] Cd Length: 556 Bit Score: 40.87 E-value: 5.88e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 4 NAVLSMKNVS--FErDKIILKNINWSLHSGENWVLMGLNGAGKTTLLSLIYGNHWATTGSIEVlGETfgktnvlaLKkri 81
Cdd:PRK11819 322 DKVIEAENLSksFG-DRLLIDDLSFSLPPGGIVGIIGPNGAGKSTLFKMITGQEQPDSGTIKI-GET--------VK--- 388
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 82 glISTAVQSQF---PEHHLAQyiVLSGKFGTIGIhNDFEKNdlNEA-IGLLKKLGGDElvNKPYRVLSQGQRQLVLIARA 157
Cdd:PRK11819 389 --LAYVDQSRDaldPNKTVWE--EISGGLDIIKV-GNREIP--SRAyVGRFNFKGGDQ--QKKVGVLSGGERNRLHLAKT 459
|
170
....*....|....*...
gi 915796356 158 LLGKPELLILDEPCNGLD 175
Cdd:PRK11819 460 LKQGGNVLLLDEPTNDLD 477
|
|
| ABC2_perm_RbbA |
NF033858 |
ribosome-associated ATPase/putative transporter RbbA; |
144-184 |
6.71e-04 |
|
ribosome-associated ATPase/putative transporter RbbA;
Pssm-ID: 468210 [Multi-domain] Cd Length: 907 Bit Score: 40.88 E-value: 6.71e-04
10 20 30 40
....*....|....*....|....*....|....*....|....*
gi 915796356 144 LSQGQRQLVLIARALLGKPELLILDEPCNGLDLFSR----ELLLE 184
Cdd:NF033858 398 LPLGIRQRLSLAVAVIHKPELLILDEPTSGVDPVARdmfwRLLIE 442
|
|
| COG3950 |
COG3950 |
Predicted ATP-binding protein involved in virulence [General function prediction only]; |
21-52 |
1.69e-03 |
|
Predicted ATP-binding protein involved in virulence [General function prediction only];
Pssm-ID: 443150 [Multi-domain] Cd Length: 276 Bit Score: 38.83 E-value: 1.69e-03
10 20 30
....*....|....*....|....*....|...
gi 915796356 21 LKNINWSLHSGENW-VLMGLNGAGKTTLLSLIY 52
Cdd:COG3950 14 FEDLEIDFDNPPRLtVLVGENGSGKTTLLEAIA 46
|
|
| PRK13546 |
PRK13546 |
teichoic acids export ABC transporter ATP-binding subunit TagH; |
21-235 |
2.25e-03 |
|
teichoic acids export ABC transporter ATP-binding subunit TagH;
Pssm-ID: 184131 [Multi-domain] Cd Length: 264 Bit Score: 38.64 E-value: 2.25e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 21 LKNINWSLHSGENWVLMGLNGAGKTTLLSLIYGNHWATTGSIEVLGEtfgkTNVLAlkkriglISTAVQSQFPEHHLAQY 100
Cdd:PRK13546 40 LDDISLKAYEGDVIGLVGINGSGKSTLSNIIGGSLSPTVGKVDRNGE----VSVIA-------ISAGLSGQLTGIENIEF 108
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 101 IVLSGKFGTIGIhndfekNDLNEAIGLLKKLGgdELVNKPYRVLSQGQRQLVLIARALLGKPELLILDEPCNGLDLFSRE 180
Cdd:PRK13546 109 KMLCMGFKRKEI------KAMTPKIIEFSELG--EFIYQPVKKYSSGMRAKLGFSINITVNPDILVIDEALSVGDQTFAQ 180
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 915796356 181 LLLEQINKLAQlpNHPTLLFVSHYTEEILPIFKNIMLLKQGEIFAQGTRDKILTE 235
Cdd:PRK13546 181 KCLDKIYEFKE--QNKTIFFVSHNLGQVRQFCTKIAWIEGGKLKDYGELDDVLPK 233
|
|
| MRP_assoc_pro |
TIGR00957 |
multi drug resistance-associated protein (MRP); This model describes multi drug ... |
7-236 |
2.93e-03 |
|
multi drug resistance-associated protein (MRP); This model describes multi drug resistance-associated protein (MRP) in eukaryotes. The multidrug resistance-associated protein is an integral membrane protein that causes multidrug resistance when overexpressed in mammalian cells. It belongs to ABC transporter superfamily. The protein topology and function was experimentally demonstrated by epitope tagging and immunofluorescence. Insertion of tags in the critical regions associated with drug efflux, abrogated its function. The C-terminal domain seem to highly conserved. [Transport and binding proteins, Other]
Pssm-ID: 188098 [Multi-domain] Cd Length: 1522 Bit Score: 38.77 E-value: 2.93e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 7 LSMKNVSF---ERDKIILKNINWSLHSGENWVLMGLNGAGKTTLLSLIYGNHWATTGSIevlgetfgktnvlALKkriGL 83
Cdd:TIGR00957 637 ITVHNATFtwaRDLPPTLNGITFSIPEGALVAVVGQVGCGKSSLLSALLAEMDKVEGHV-------------HMK---GS 700
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 84 ISTAVQSQFPEHHLAQYIVLSGKfgtiGIHNDFEKNDLnEAIGLLKKL----GGD--ELVNKPYRvLSQGQRQLVLIARA 157
Cdd:TIGR00957 701 VAYVPQQAWIQNDSLRENILFGK----ALNEKYYQQVL-EACALLPDLeilpSGDrtEIGEKGVN-LSGGQKQRVSLARA 774
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 915796356 158 LLGKPELLILDEPCNGLDLFSRELLLEQINKLAQLPNHPTLLFVSHyTEEILPIFKNIMLLKQGEIFAQGTRDKILTEN 236
Cdd:TIGR00957 775 VYSNADIYLFDDPLSAVDAHVGKHIFEHVIGPEGVLKNKTRILVTH-GISYLPQVDVIIVMSGGKISEMGSYQELLQRD 852
|
|
| PRK15064 |
PRK15064 |
ABC transporter ATP-binding protein; Provisional |
152-203 |
3.13e-03 |
|
ABC transporter ATP-binding protein; Provisional
Pssm-ID: 237894 [Multi-domain] Cd Length: 530 Bit Score: 38.72 E-value: 3.13e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....
gi 915796356 152 VLIARALLGKPELLILDEPCNGLDLFSrellleqINKLAQLPN--HPTLLFVSH 203
Cdd:PRK15064 164 VLLAQALFSNPDILLLDEPTNNLDINT-------IRWLEDVLNerNSTMIIISH 210
|
|
| ugpC |
PRK11650 |
sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC; |
5-175 |
3.70e-03 |
|
sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC;
Pssm-ID: 236947 [Multi-domain] Cd Length: 356 Bit Score: 38.29 E-value: 3.70e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 5 AVLSMKNV--SFERDKIILKNINWSLHSGENWVLMGLNGAGKTTLLSLIYGNHWATTGSIEVLGEtfgKTNVL------- 75
Cdd:PRK11650 2 AGLKLQAVrkSYDGKTQVIKGIDLDVADGEFIVLVGPSGCGKSTLLRMVAGLERITSGEIWIGGR---VVNELepadrdi 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 76 ---------------------ALKKRiglistavqsQFPEHHLAQYIvlsgkfgtigihndfekndlNEAIGLLKKlgGD 134
Cdd:PRK11650 79 amvfqnyalyphmsvrenmayGLKIR----------GMPKAEIEERV--------------------AEAARILEL--EP 126
|
170 180 190 200
....*....|....*....|....*....|....*....|.
gi 915796356 135 ELVNKPyRVLSQGQRQLVLIARALLGKPELLILDEPCNGLD 175
Cdd:PRK11650 127 LLDRKP-RELSGGQRQRVAMGRAIVREPAVFLFDEPLSNLD 166
|
|
| ABC_UvrA |
cd03238 |
ATP-binding cassette domain of the excision repair protein UvrA; Nucleotide excision repair in ... |
21-203 |
5.32e-03 |
|
ATP-binding cassette domain of the excision repair protein UvrA; Nucleotide excision repair in eubacteria is a process that repairs DNA damage by the removal of a 12-13-mer oligonucleotide containing the lesion. Recognition and cleavage of the damaged DNA is a multistep ATP-dependent reaction that requires the UvrA, UvrB, and UvrC proteins. Both UvrA and UvrB are ATPases, with UvrA having two ATP binding sites, which have the characteristic signature of the family of ABC proteins, and UvrB having one ATP binding site that is structurally related to that of helicases.
Pssm-ID: 213205 [Multi-domain] Cd Length: 176 Bit Score: 36.92 E-value: 5.32e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 21 LKNINWSLHSGENWVLMGLNGAGKTTLLSliygnhwattgsievlgetfgktNVLALKKRIGLISTAvqSQFPEHHLaqy 100
Cdd:cd03238 11 LQNLDVSIPLNVLVVVTGVSGSGKSTLVN-----------------------EGLYASGKARLISFL--PKFSRNKL--- 62
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 101 iVLSGKFGTIgihndfekndLNEAIGLLKklggdelVNKPYRVLSQGQRQLVLIARALLGKPE--LLILDEPCNGLDLFS 178
Cdd:cd03238 63 -IFIDQLQFL----------IDVGLGYLT-------LGQKLSTLSGGELQRVKLASELFSEPPgtLFILDEPSTGLHQQD 124
|
170 180
....*....|....*....|....*
gi 915796356 179 RELLLEQINKLAQLPNhpTLLFVSH 203
Cdd:cd03238 125 INQLLEVIKGLIDLGN--TVILIEH 147
|
|
| COG4938 |
COG4938 |
Predicted ATPase [General function prediction only]; |
7-170 |
9.27e-03 |
|
Predicted ATPase [General function prediction only];
Pssm-ID: 443965 [Multi-domain] Cd Length: 277 Bit Score: 36.87 E-value: 9.27e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 7 LSMKNV-SFERDKIILKNINwslhsgenwVLMGLNGAGKTTLLSLIYG---------------------NHWATTGSIEV 64
Cdd:COG4938 4 ISIKNFgPFKEAELELKPLT---------LLIGPNGSGKSTLIQALLLllqsnfiylpaersgparlypSLVRELSDLGS 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 915796356 65 LGETFgkTNVLALKKRIGlistaVQSQFPEHHLAQYIVLSGKFGTIGIhnDFEKNDLNEAIGLLKKLGGDELvnkPYRVL 144
Cdd:COG4938 75 RGEYT--ADFLAELENLE-----ILDDKSKELLEQVEEWLEKIFPGKV--EVDASSDLVRLVFRPSGNGKRI---PLSNV 142
|
170 180
....*....|....*....|....*....
gi 915796356 145 SQGQRQ---LVLIARALLGKPELLILDEP 170
Cdd:COG4938 143 GSGVSEllpILLALLSAAKPGSLLIIEEP 171
|
|
| |
