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Conserved domains on  [gi|913486248|ref|WP_050441916|]
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DNA adenine methylase [Bacteroides fragilis]

Protein Classification

DNA adenine methylase( domain architecture ID 581209)

DNA adenine methylase recognizes a specific double-stranded DNA sequence and catalyzes the adenine-specific methylation on both strands, protecting the DNA from cleavage

EC:  2.1.1.72
Gene Ontology:  GO:0009007|GO:0003677|GO:0032775
SCOP:  4003615

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
MethyltransfD12 super family cl23779
D12 class N6 adenine-specific DNA methyltransferase;
16-214 4.07e-04

D12 class N6 adenine-specific DNA methyltransferase;


The actual alignment was detected with superfamily member pfam02086:

Pssm-ID: 451538  Cd Length: 254  Bit Score: 40.81  E-value: 4.07e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 913486248   16 FVGQKRMFVSEFKKILKHFDDKTiFVDLFGGSGLLSHITKRERPDavVIYNDHDNYrgrLENIGRT--NTLLGDLRKIVG 93
Cdd:pfam02086   1 YIGGKRKLLPEIKEHIPKGGDRR-FVEPFAGGGAVFFEAKKQGKK--VLINDINYD---LINLYKAliKNNPDDLIKDLE 74
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 913486248   94 IYPHNQKITGK-----MREAFLERIRLEETTGFVDYLTLsTSLLFSGKYAQN-------------------MEELEHlcF 149
Cdd:pfam02086  75 ALLELEELNSReyfyeLREEFNAIDAIREVIRAIDFLYL-NRLLFSGLYRVNkkgnfnvpygaykkpwkfaLKELKL--R 151
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 913486248  150 YNKIRqadyrcdgylDGLEVVCYDYKELAETYRVLPGVVFLvDPPYMGT-DISTYRMDWKLGDYLD 214
Cdd:pfam02086 152 ALKLQ----------NNATIECGDFDAVLLAANISDDFVYL-DPPYNPRqYTSNYTGYNTIAFSDE 206
 
Name Accession Description Interval E-value
MethyltransfD12 pfam02086
D12 class N6 adenine-specific DNA methyltransferase;
16-214 4.07e-04

D12 class N6 adenine-specific DNA methyltransferase;


Pssm-ID: 396593  Cd Length: 254  Bit Score: 40.81  E-value: 4.07e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 913486248   16 FVGQKRMFVSEFKKILKHFDDKTiFVDLFGGSGLLSHITKRERPDavVIYNDHDNYrgrLENIGRT--NTLLGDLRKIVG 93
Cdd:pfam02086   1 YIGGKRKLLPEIKEHIPKGGDRR-FVEPFAGGGAVFFEAKKQGKK--VLINDINYD---LINLYKAliKNNPDDLIKDLE 74
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 913486248   94 IYPHNQKITGK-----MREAFLERIRLEETTGFVDYLTLsTSLLFSGKYAQN-------------------MEELEHlcF 149
Cdd:pfam02086  75 ALLELEELNSReyfyeLREEFNAIDAIREVIRAIDFLYL-NRLLFSGLYRVNkkgnfnvpygaykkpwkfaLKELKL--R 151
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 913486248  150 YNKIRqadyrcdgylDGLEVVCYDYKELAETYRVLPGVVFLvDPPYMGT-DISTYRMDWKLGDYLD 214
Cdd:pfam02086 152 ALKLQ----------NNATIECGDFDAVLLAANISDDFVYL-DPPYNPRqYTSNYTGYNTIAFSDE 206
 
Name Accession Description Interval E-value
MethyltransfD12 pfam02086
D12 class N6 adenine-specific DNA methyltransferase;
16-214 4.07e-04

D12 class N6 adenine-specific DNA methyltransferase;


Pssm-ID: 396593  Cd Length: 254  Bit Score: 40.81  E-value: 4.07e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 913486248   16 FVGQKRMFVSEFKKILKHFDDKTiFVDLFGGSGLLSHITKRERPDavVIYNDHDNYrgrLENIGRT--NTLLGDLRKIVG 93
Cdd:pfam02086   1 YIGGKRKLLPEIKEHIPKGGDRR-FVEPFAGGGAVFFEAKKQGKK--VLINDINYD---LINLYKAliKNNPDDLIKDLE 74
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 913486248   94 IYPHNQKITGK-----MREAFLERIRLEETTGFVDYLTLsTSLLFSGKYAQN-------------------MEELEHlcF 149
Cdd:pfam02086  75 ALLELEELNSReyfyeLREEFNAIDAIREVIRAIDFLYL-NRLLFSGLYRVNkkgnfnvpygaykkpwkfaLKELKL--R 151
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 913486248  150 YNKIRqadyrcdgylDGLEVVCYDYKELAETYRVLPGVVFLvDPPYMGT-DISTYRMDWKLGDYLD 214
Cdd:pfam02086 152 ALKLQ----------NNATIECGDFDAVLLAANISDDFVYL-DPPYNPRqYTSNYTGYNTIAFSDE 206
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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