|
Name |
Accession |
Description |
Interval |
E-value |
| MrcB |
COG0744 |
Penicillin-binding protein 1B/1F, peptidoglycan transglycosylase/transpeptidase [Cell wall ... |
52-686 |
0e+00 |
|
Penicillin-binding protein 1B/1F, peptidoglycan transglycosylase/transpeptidase [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440507 [Multi-domain] Cd Length: 630 Bit Score: 564.93 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896441666 52 FAYYAWKAPAFSE-SKLDDPIPAKIYDKNGELVKTLdNGQRHEHVNIKDVPKDMKNAVLATEDNRFYQHGALDYKRLFGA 130
Cdd:COG0744 34 VALYVADLPDPEElEDLALPQTSTIYDRDGTLIATL-GDENREWVPLDQIPPHLKDAVVAIEDRRFYEHGGVDPKGIARA 112
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896441666 131 IGKNLTGGFGSQGASTLTQQVVKDSFLTQQKSIGRKAQEAYLSYRLEQEYSKDEIFQVYMNKIYYSDGVTGIKAAAKYYF 210
Cdd:COG0744 113 LVANLTAGGVVQGGSTITQQLVKNLFLSNERTLSRKLKEALLALKLERKYSKDEILELYLNTVYFGRGAYGIEAAAQYYF 192
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896441666 211 NKDMKDLNLAEEAYLAGLPQVPNLYNIYNNPKEANNRKDTVLYLMHKHNRINDKQYADAKKIDLKANlvertkkerQVTG 290
Cdd:COG0744 193 GKSASDLTLAEAALLAGLVKAPSYYDPYRNPEAAKERRNLVLDRMVEQGYITQAEADAAKAEPLTLV---------PPPN 263
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896441666 291 NEKNPEYDSYVNFVQSELMNNkyFKDKNLgsvLQSGIKIYTNMDKDVQQTLQDRINNG-SFYKNEDQQVGATILDSKTGG 369
Cdd:COG0744 264 GAAAGKYPYFVDYVRRELEEL--LGEDDL---YRGGLKIYTTLDPKLQKAAEKAVKNVlPEGKPGGLQAALVVVDPKTGE 338
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896441666 370 LVAISGGRNYKNvVERNQATD-PHPTGSSLKPFlAYGPAIENmKWSTNHVIQDES-SYWVDGSQFKNYDTKGHGTVSIYD 447
Cdd:COG0744 339 VLAMVGGRDYGK-SQFNRATQaKRQPGSTFKPF-VYAAALEQ-GYTPATTVDDEPvTFPGGGWSPKNYDGRYRGPVTLRE 415
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896441666 448 ALRQSFNIPALKTWQQVksqaGNDAPQKFASKLGLDYSGKIGPSEVLGgsSSEFSPTQLASAFAAIANGGTYNNAHSIQK 527
Cdd:COG0744 416 ALANSLNTPAVRLAQEV----GLDKVVDTARRLGITSPLDPNPSLALG--TSEVSPLEMASAYATFANGGVYVEPHAITK 489
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896441666 528 VVTHEGDTI-EYEHTSHKAMKDYTSYMLAEILKGTFKaYGSAYGHGVSGVNMGAKTGTgTygqeiyekynlpdNAAKDVW 606
Cdd:COG0744 490 VTDADGKVLyEAKPKCEQVISPEVAYLMTDMLQDVVT-SGTGRAARLPGRPVAGKTGT-T-------------NDNRDAW 554
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896441666 607 INGFSPEYTMSVWMGFNKvkqygtNSFIGH-SEQDYPQYLYEDVMSSISS-KDGEDFKKPNDVQGSSPDSLSVSGHSDNN 684
Cdd:COG0744 555 FVGYTPQLVTAVWVGNDD------NSPMGYvTGGSLPAPIWRDFMEAALEgLPVEDFPKPSGVVRIDEPSPTPSGTEPTE 628
|
..
gi 896441666 685 TT 686
Cdd:COG0744 629 TS 630
|
|
| PBP_1a_fam |
TIGR02074 |
penicillin-binding protein, 1A family; Bacterial that synthesize a cell wall of peptidoglycan ... |
91-656 |
5.70e-151 |
|
penicillin-binding protein, 1A family; Bacterial that synthesize a cell wall of peptidoglycan (murein) generally have several transglycosylases and transpeptidases for the task. This family consists of bifunctional transglycosylase/transpeptidase penicillin-binding proteins (PBP). In the Proteobacteria, this family includes PBP 1A but not the paralogous PBP 1B (TIGR02071). This family also includes related proteins, often designated PBP 1A, from other bacterial lineages. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 273955 [Multi-domain] Cd Length: 531 Bit Score: 450.17 E-value: 5.70e-151
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896441666 91 RHEHVNIKDVPKDMKNAVLATEDNRFYQHGALDYKRLFGAIGKNLTGGFGSQGASTLTQQVVKDSFLTQQKSIGRKAQEA 170
Cdd:TIGR02074 1 RREYVPIDDIPENLINAFLAIEDRRFYDHFGIDLKGIGRAAVANITSGRVLEGGSTITQQLAKNLYLTNERTITRKIQEA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896441666 171 YLSYRLEQEYSKDEIFQVYMNKIYYSDGVTGIKAAAKYYFNKDMKDLNLAEEAYLAGLPQVPNLYNIYNNPKEANNRKDT 250
Cdd:TIGR02074 81 LLALKLEQKLSKDEILELYLNRIYFGNGAYGIEAAAQFYFGKSVNDLTLAEAAMLAGLPKAPSAYNPFKNPERAKDRRNL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896441666 251 VLYLMHKHNRINDKQYADAKKIDLKANLveRTKKERQVTgneknpeYDSYVNFVQSELmnnkyfkDKNLGSVL-QSGIKI 329
Cdd:TIGR02074 161 VLSNMVENGYITAEEAEEAINEPIQLYL--QTKKSEQYK-------APYFVDYVIQEL-------EEEYGEELyTGGLKI 224
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896441666 330 YTNMDKDVQQTLQDRINNGSFYK----NEDQQVGATILDSKTGGLVAISGGRNYKnvvER--NQAT----DPhptGSSLK 399
Cdd:TIGR02074 225 YTTLDLDAQKAAEKVLNTGLRVAgrrdGDDLQAALVAIDPDTGAVRALVGGRDYG---KSqfNRATqakrQP---GSTFK 298
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896441666 400 PFLaYGPAIENmKWSTNHVIQDESSYWVDGSQF--KNYDTKGHGTVSIYDALRQSFNIPALKTWQQVksqaGNDAPQKFA 477
Cdd:TIGR02074 299 PFV-YAAALEK-GLTPATIVNDEPITYNGNGPWspKNYGGGYRGNVTLRQALAQSRNIPAVRLLQEV----GLDKVVALA 372
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896441666 478 SKLGLDYSGKIGPSEVLGgsSSEFSPTQLASAFAAIANGGTYNNAHSIQKVVTHEGDTIeYEHTSH--KAMKDYTSYMLA 555
Cdd:TIGR02074 373 KRFGITSPLDPVLSLALG--TVEVSPLEMASAYAVFANGGKYVEPHGIRKIVDRDGKVI-YENKPKttQVISPATAYIMT 449
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896441666 556 EILKGTFkAYGSAYGHGVSGVNMGAKTGTgtygqeiyekynlpDNAAKDVWINGFSPEYTMSVWMGFNKVKQYGtnsfIG 635
Cdd:TIGR02074 450 DMLKGVV-ESGTGRSARLPGRPVAGKTGT--------------TQNWRDAWFVGYTPYYVTAVWVGYDDKKTLG----KS 510
|
570 580
....*....|....*....|.
gi 896441666 636 HSEQDYPQYLYEDVMSSISSK 656
Cdd:TIGR02074 511 GTGGGLAAPIWRDFMAEALKN 531
|
|
| Transgly |
pfam00912 |
Transglycosylase; The penicillin-binding proteins are bifunctional proteins consisting of ... |
79-256 |
1.69e-81 |
|
Transglycosylase; The penicillin-binding proteins are bifunctional proteins consisting of transglycosylase and transpeptidase in the N- and C-terminus respectively. The transglycosylase domain catalyzes the polymerization of murein glycan chains.
Pssm-ID: 459993 [Multi-domain] Cd Length: 177 Bit Score: 257.07 E-value: 1.69e-81
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896441666 79 NGELVKTLDnGQRHEHVNIKDVPKDMKNAVLATEDNRFYQHGALDYKRLFGAIGKNLTGGFGSQGASTLTQQVVKDSFLT 158
Cdd:pfam00912 1 DGTLLAELG-EENREYVPLDDIPPALKNAVLAIEDRRFYEHGGVDPKGIARALLSNLRSGRIVQGGSTITQQLAKNLFLT 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896441666 159 QQKSIGRKAQEAYLSYRLEQEYSKDEIFQVYMNKIYYSDGVTGIKAAAKYYFNKDMKDLNLAEEAYLAGLPQVPNLYNIY 238
Cdd:pfam00912 80 PERTLTRKLKEAVLALKLERRYSKDEILEAYLNTVYFGRGAYGIEAAARAYFGKDASDLTLAEAALLAGLPQAPSRYNPL 159
|
170
....*....|....*...
gi 896441666 239 NNPKEANNRKDTVLYLMH 256
Cdd:pfam00912 160 RNPERAKRRRNLVLDRMV 177
|
|
| PRK14850 |
PRK14850 |
penicillin-binding protein 1b; Provisional |
62-645 |
3.00e-50 |
|
penicillin-binding protein 1b; Provisional
Pssm-ID: 237835 [Multi-domain] Cd Length: 764 Bit Score: 188.52 E-value: 3.00e-50
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896441666 62 FSESKLDDPIPAKIYDKNGelvktldngQRHEHVNIKDVPKDMKNAVLATEDNRFYQHGALDYKRLFGAIGKNLTGGFGS 141
Cdd:PRK14850 136 FSFLRLDPKLIAMLYSPEG---------KKRLFIPRNQYPEMLIKTLLAIEDKYFYEHDGIHLSSIGRAFLVNLMSGHTI 206
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896441666 142 QGASTLTQQVVKDSFLTQQKSIGRKAQEAYLSYRLEQEYSKDEIFQVYMNKIYY----SDGVTGIKAAAKYYFNKDMKDL 217
Cdd:PRK14850 207 QGGSTLTQQLVKNLFLTNTRSLWRKINEIYMALILDRFYSKDRILELYLNEVYLgqdgNEQIRGFPLASIYYFGRPINEL 286
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896441666 218 NLAEEAYLAGLPQVPNLYNIYNNPKEANNRKDTVLYLMHKHNRINDKQYADAKKIDLKAnlvertkkerQVTGNEKNpEY 297
Cdd:PRK14850 287 NLDQYALLVGMVKGASLYNPWTNPNLTLKRRNLVLFLLYKQKVITRKLYKDLCSRPLNV----------QSKGNIIS-SH 355
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896441666 298 DSYVNFVQSELMNNKYFKDKNLgsvlqSGIKIYTNMDKDVQQTLQDRINNG-----SFYKNEDQQVGATILDSKTGGLVA 372
Cdd:PRK14850 356 PAFIQLVCEEFHKKIHYPFKNF-----SGTKIFTTLDYISQNAAEQAVKIGipilkRKKRLKDLEVAMVIIDRFSGEVRA 430
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896441666 373 ISGGRNyKNVVERNQATDP-HPTGSSLKPFLAYGPAIENMKWSTN--------HVIQDESSYWVDgsqfKNYDTKGHGTV 443
Cdd:PRK14850 431 LIGSSK-PEFNGYNRALKArRSIGSLSKPITYLTALSQPEKYHLNtwisdtpiSIKLDNGQYWTP----KNNNFSFSGKV 505
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896441666 444 SIYDALRQSFNIPALktwqQVKSQAGNDAPQKFASKLGLDySGKIG--PSEVLGGSSseFSPTQLASAFAAIANGGTYNN 521
Cdd:PRK14850 506 MLIDALIHSINIPTV----HLSINLGLKKLVDSWILLGIS-SNYITplPSISLGAIN--LTPMEVAQVFQIIGSGGYKSS 578
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896441666 522 AHSIQKVVTHEGDTI-EYEHTSHKAMKDYTSY-----MLAEILKGTFKAYGSAYghgvSGVNMGAKTGTgtygqeiyeky 595
Cdd:PRK14850 579 LSSIRSIISDDNKVLyQNFPQSKHVESSQASYltlyaMQQVVKSGTAKSLGTIF----KEFSLAGKTGT----------- 643
|
570 580 590 600 610
....*....|....*....|....*....|....*....|....*....|...
gi 896441666 596 nlpDNAAKDVWINGFSPEYTMSVWMGFN---KVKQYGTNSFIghseQDYPQYL 645
Cdd:PRK14850 644 ---TNNLVDSWFVGIDGKQVVITWIGRDnnhTTKLYGSSGAM----KIYKRYL 689
|
|
|
|
Name |
Accession |
Description |
Interval |
E-value |
| MrcB |
COG0744 |
Penicillin-binding protein 1B/1F, peptidoglycan transglycosylase/transpeptidase [Cell wall ... |
52-686 |
0e+00 |
|
Penicillin-binding protein 1B/1F, peptidoglycan transglycosylase/transpeptidase [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440507 [Multi-domain] Cd Length: 630 Bit Score: 564.93 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896441666 52 FAYYAWKAPAFSE-SKLDDPIPAKIYDKNGELVKTLdNGQRHEHVNIKDVPKDMKNAVLATEDNRFYQHGALDYKRLFGA 130
Cdd:COG0744 34 VALYVADLPDPEElEDLALPQTSTIYDRDGTLIATL-GDENREWVPLDQIPPHLKDAVVAIEDRRFYEHGGVDPKGIARA 112
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896441666 131 IGKNLTGGFGSQGASTLTQQVVKDSFLTQQKSIGRKAQEAYLSYRLEQEYSKDEIFQVYMNKIYYSDGVTGIKAAAKYYF 210
Cdd:COG0744 113 LVANLTAGGVVQGGSTITQQLVKNLFLSNERTLSRKLKEALLALKLERKYSKDEILELYLNTVYFGRGAYGIEAAAQYYF 192
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896441666 211 NKDMKDLNLAEEAYLAGLPQVPNLYNIYNNPKEANNRKDTVLYLMHKHNRINDKQYADAKKIDLKANlvertkkerQVTG 290
Cdd:COG0744 193 GKSASDLTLAEAALLAGLVKAPSYYDPYRNPEAAKERRNLVLDRMVEQGYITQAEADAAKAEPLTLV---------PPPN 263
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896441666 291 NEKNPEYDSYVNFVQSELMNNkyFKDKNLgsvLQSGIKIYTNMDKDVQQTLQDRINNG-SFYKNEDQQVGATILDSKTGG 369
Cdd:COG0744 264 GAAAGKYPYFVDYVRRELEEL--LGEDDL---YRGGLKIYTTLDPKLQKAAEKAVKNVlPEGKPGGLQAALVVVDPKTGE 338
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896441666 370 LVAISGGRNYKNvVERNQATD-PHPTGSSLKPFlAYGPAIENmKWSTNHVIQDES-SYWVDGSQFKNYDTKGHGTVSIYD 447
Cdd:COG0744 339 VLAMVGGRDYGK-SQFNRATQaKRQPGSTFKPF-VYAAALEQ-GYTPATTVDDEPvTFPGGGWSPKNYDGRYRGPVTLRE 415
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896441666 448 ALRQSFNIPALKTWQQVksqaGNDAPQKFASKLGLDYSGKIGPSEVLGgsSSEFSPTQLASAFAAIANGGTYNNAHSIQK 527
Cdd:COG0744 416 ALANSLNTPAVRLAQEV----GLDKVVDTARRLGITSPLDPNPSLALG--TSEVSPLEMASAYATFANGGVYVEPHAITK 489
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896441666 528 VVTHEGDTI-EYEHTSHKAMKDYTSYMLAEILKGTFKaYGSAYGHGVSGVNMGAKTGTgTygqeiyekynlpdNAAKDVW 606
Cdd:COG0744 490 VTDADGKVLyEAKPKCEQVISPEVAYLMTDMLQDVVT-SGTGRAARLPGRPVAGKTGT-T-------------NDNRDAW 554
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896441666 607 INGFSPEYTMSVWMGFNKvkqygtNSFIGH-SEQDYPQYLYEDVMSSISS-KDGEDFKKPNDVQGSSPDSLSVSGHSDNN 684
Cdd:COG0744 555 FVGYTPQLVTAVWVGNDD------NSPMGYvTGGSLPAPIWRDFMEAALEgLPVEDFPKPSGVVRIDEPSPTPSGTEPTE 628
|
..
gi 896441666 685 TT 686
Cdd:COG0744 629 TS 630
|
|
| PBP_1a_fam |
TIGR02074 |
penicillin-binding protein, 1A family; Bacterial that synthesize a cell wall of peptidoglycan ... |
91-656 |
5.70e-151 |
|
penicillin-binding protein, 1A family; Bacterial that synthesize a cell wall of peptidoglycan (murein) generally have several transglycosylases and transpeptidases for the task. This family consists of bifunctional transglycosylase/transpeptidase penicillin-binding proteins (PBP). In the Proteobacteria, this family includes PBP 1A but not the paralogous PBP 1B (TIGR02071). This family also includes related proteins, often designated PBP 1A, from other bacterial lineages. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 273955 [Multi-domain] Cd Length: 531 Bit Score: 450.17 E-value: 5.70e-151
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896441666 91 RHEHVNIKDVPKDMKNAVLATEDNRFYQHGALDYKRLFGAIGKNLTGGFGSQGASTLTQQVVKDSFLTQQKSIGRKAQEA 170
Cdd:TIGR02074 1 RREYVPIDDIPENLINAFLAIEDRRFYDHFGIDLKGIGRAAVANITSGRVLEGGSTITQQLAKNLYLTNERTITRKIQEA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896441666 171 YLSYRLEQEYSKDEIFQVYMNKIYYSDGVTGIKAAAKYYFNKDMKDLNLAEEAYLAGLPQVPNLYNIYNNPKEANNRKDT 250
Cdd:TIGR02074 81 LLALKLEQKLSKDEILELYLNRIYFGNGAYGIEAAAQFYFGKSVNDLTLAEAAMLAGLPKAPSAYNPFKNPERAKDRRNL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896441666 251 VLYLMHKHNRINDKQYADAKKIDLKANLveRTKKERQVTgneknpeYDSYVNFVQSELmnnkyfkDKNLGSVL-QSGIKI 329
Cdd:TIGR02074 161 VLSNMVENGYITAEEAEEAINEPIQLYL--QTKKSEQYK-------APYFVDYVIQEL-------EEEYGEELyTGGLKI 224
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896441666 330 YTNMDKDVQQTLQDRINNGSFYK----NEDQQVGATILDSKTGGLVAISGGRNYKnvvER--NQAT----DPhptGSSLK 399
Cdd:TIGR02074 225 YTTLDLDAQKAAEKVLNTGLRVAgrrdGDDLQAALVAIDPDTGAVRALVGGRDYG---KSqfNRATqakrQP---GSTFK 298
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896441666 400 PFLaYGPAIENmKWSTNHVIQDESSYWVDGSQF--KNYDTKGHGTVSIYDALRQSFNIPALKTWQQVksqaGNDAPQKFA 477
Cdd:TIGR02074 299 PFV-YAAALEK-GLTPATIVNDEPITYNGNGPWspKNYGGGYRGNVTLRQALAQSRNIPAVRLLQEV----GLDKVVALA 372
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896441666 478 SKLGLDYSGKIGPSEVLGgsSSEFSPTQLASAFAAIANGGTYNNAHSIQKVVTHEGDTIeYEHTSH--KAMKDYTSYMLA 555
Cdd:TIGR02074 373 KRFGITSPLDPVLSLALG--TVEVSPLEMASAYAVFANGGKYVEPHGIRKIVDRDGKVI-YENKPKttQVISPATAYIMT 449
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896441666 556 EILKGTFkAYGSAYGHGVSGVNMGAKTGTgtygqeiyekynlpDNAAKDVWINGFSPEYTMSVWMGFNKVKQYGtnsfIG 635
Cdd:TIGR02074 450 DMLKGVV-ESGTGRSARLPGRPVAGKTGT--------------TQNWRDAWFVGYTPYYVTAVWVGYDDKKTLG----KS 510
|
570 580
....*....|....*....|.
gi 896441666 636 HSEQDYPQYLYEDVMSSISSK 656
Cdd:TIGR02074 511 GTGGGLAAPIWRDFMAEALKN 531
|
|
| MrcA |
COG5009 |
Membrane carboxypeptidase/penicillin-binding protein [Cell wall/membrane/envelope biogenesis]; |
52-622 |
6.54e-111 |
|
Membrane carboxypeptidase/penicillin-binding protein [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 444033 [Multi-domain] Cd Length: 785 Bit Score: 354.47 E-value: 6.54e-111
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896441666 52 FAYYAWKAPAFSEskLDD---PIPAKIYDKNGELVktldnG----QRHEHVNIKDVPKDMKNAVLATEDNRFYQHGALDY 124
Cdd:COG5009 26 YLYLSPDLPDVET--LKDyqpPTPSRVYSADGKLI-----AefgeERRIPVPIEEIPPLLINAFLAAEDKRFYEHPGVDP 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896441666 125 KRLFGAIGKNLTGGFGSQGASTLTQQVVKDSFLTQQKSIGRKAQEAYLSYRLEQEYSKDEIFQVYMNKIYYSDGVTGIKA 204
Cdd:COG5009 99 IGIARAAVVNLRTGRRVQGGSTITQQVAKNFLLSPERTLTRKIKEAILALRIEQELSKDEILELYLNKIYLGHRAYGVAA 178
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896441666 205 AAKYYFNKDMKDLNLAEEAYLAGLPQVPNLYNIYNNPKEANNRKDTVLYLMHKHNRINDKQYADAKKIDLKANLvertkk 284
Cdd:COG5009 179 AAQTYFGKSLDELTLAEAAMLAGLPKAPSRYNPIRNPERALERRNYVLGRMLELGYITQAEYEAAKAEPLTARY------ 252
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896441666 285 erqvTGNEKNPEYDSYVNFVQSELMnNKYFKDKnlgsVLQSGIKIYTNMDKDVQQTLQDRINNG---------------- 348
Cdd:COG5009 253 ----HGASAEVDAPYFAEMVRRELV-ERYGEDA----LYTGGLKVYTTLDPRLQEAAEKALRDGllaydrrhgyrgpeah 323
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896441666 349 ------------------------------------------------------SFYKNEDQQV---------------- 358
Cdd:COG5009 324 ldlaeedwdealaevpdvgdlrpavvlevddksarvglrdgetgtlpleglkwaRPYINDNRRGpapksasdvlkpgdvi 403
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896441666 359 -------------------GATI-LDSKTGGLVAISGGRNYknvvERNQ---ATD----PhptGSSLKPFLaYGPAIENm 411
Cdd:COG5009 404 rvrpvadggwrlrqipevqGALVaLDPHTGAVLALVGGFDF----EQSKfnrATQakrqP---GSSFKPFV-YAAALDN- 474
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896441666 412 KWSTNHVIQDES-SYWVDGSQ----FKNYDTKGHGTVSIYDALRQSFNIPALKTWQQVksqaGNDAPQKFASKLGLDysG 486
Cdd:COG5009 475 GYTPATIINDAPiVFDDGGGGgvwrPKNYSGKFYGPTTLREALEKSRNLVTVRLLQDV----GIDYVIDYAERFGIY--S 548
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896441666 487 KIGPSE--VLGgsSSEFSPTQLASAFAAIANGGTYNNAHSIQKVVTHEGDTIeYEHTSHKAMKDY--------------- 549
Cdd:COG5009 549 KLPPNLslALG--SGEVTPLEMARAYAVFANGGYRVEPYLIDRIEDRNGKVI-YRADPARACEDCdaaewdgaeprlpdp 625
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896441666 550 --------TSYMLAEILKGTFKaYGSAYGHGVSGVNMGAKTGTgTygqeiyekynlpdNAAKDVWINGFSPEYTMSVWMG 621
Cdd:COG5009 626 aeqvidprTAYQMTSMLRGVVQ-RGTGRRARALGRDIAGKTGT-T-------------NDSKDAWFVGFTPDLVAGVWVG 690
|
.
gi 896441666 622 F 622
Cdd:COG5009 691 F 691
|
|
| Transgly |
pfam00912 |
Transglycosylase; The penicillin-binding proteins are bifunctional proteins consisting of ... |
79-256 |
1.69e-81 |
|
Transglycosylase; The penicillin-binding proteins are bifunctional proteins consisting of transglycosylase and transpeptidase in the N- and C-terminus respectively. The transglycosylase domain catalyzes the polymerization of murein glycan chains.
Pssm-ID: 459993 [Multi-domain] Cd Length: 177 Bit Score: 257.07 E-value: 1.69e-81
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896441666 79 NGELVKTLDnGQRHEHVNIKDVPKDMKNAVLATEDNRFYQHGALDYKRLFGAIGKNLTGGFGSQGASTLTQQVVKDSFLT 158
Cdd:pfam00912 1 DGTLLAELG-EENREYVPLDDIPPALKNAVLAIEDRRFYEHGGVDPKGIARALLSNLRSGRIVQGGSTITQQLAKNLFLT 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896441666 159 QQKSIGRKAQEAYLSYRLEQEYSKDEIFQVYMNKIYYSDGVTGIKAAAKYYFNKDMKDLNLAEEAYLAGLPQVPNLYNIY 238
Cdd:pfam00912 80 PERTLTRKLKEAVLALKLERRYSKDEILEAYLNTVYFGRGAYGIEAAARAYFGKDASDLTLAEAALLAGLPQAPSRYNPL 159
|
170
....*....|....*...
gi 896441666 239 NNPKEANNRKDTVLYLMH 256
Cdd:pfam00912 160 RNPERAKRRRNLVLDRMV 177
|
|
| PbpC |
COG4953 |
Membrane carboxypeptidase/penicillin-binding protein PbpC [Cell wall/membrane/envelope ... |
75-621 |
1.74e-62 |
|
Membrane carboxypeptidase/penicillin-binding protein PbpC [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 443980 [Multi-domain] Cd Length: 773 Bit Score: 223.56 E-value: 1.74e-62
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896441666 75 IYDKNGEL--VKTLDNGQRHEHVNIKDVPKDMKNAVLATEDNRFYQHGALDYKRLFGAIGKNLTGGFGSQGASTLTQQVV 152
Cdd:COG4953 46 VLDRDGTLlrAFLAADGQWRLPVPLDEVSPRYLQALLAYEDRRFYYHPGVNPLALLRAAWQNLRSGRIVSGGSTLTMQVA 125
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896441666 153 KdsfLT--QQKSIGRKAQEAYLSYRLEQEYSKDEIFQVYMNKIYYSDGVTGIKAAAKYYFNKDMKDLNLAEEAYLAGLPQ 230
Cdd:COG4953 126 R---LLepRPRTLSGKLRQILRALQLERRYSKDEILELYLNLAPYGGNIEGVEAASLAYFGKPPSRLSLAEAALLAVLPQ 202
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896441666 231 VPNLYNIYNNPKEANNRKDTVLYLMHKHNRINDKQYADAK--KIDLK--------ANLVERTKKERqvtgneknpeydsy 300
Cdd:COG4953 203 APSRRRPDRNPERARAARDRVLARLAEAGVIDAEEAALALlePVPARrrplpqlaPHLARRLLRQL-------------- 268
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896441666 301 vnfvqselmnnkyfkdknlgsvlQSGIKIYTNMDKDVQQTLQDRINN--GSFYKNEDQQVGATILDSKTGGLVAISGGRN 378
Cdd:COG4953 269 -----------------------PGGTRIRTTLDAGLQRRLERLVRRyvRRLKQNGIHNAAVLVVDNRTGEVLAYVGSAD 325
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896441666 379 YKNvVERNQATD----PHPTGSSLKPFLaYGPAIENMKWSTNHVIQD-ESSYwvDGSQFKNYDTKGHGTVSIYDALRQSF 453
Cdd:COG4953 326 FFD-ASRQGQVDmvraLRSPGSTLKPFL-YGLALDQGLIHPETLLADvPTSF--GGYRPENFDGTFQGPVSAREALARSL 401
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896441666 454 NIPALKTWQQVKsqagndaPQKFASKL------GLDYSGK-IGPSEVLGGssSEFSPTQLASAFAAIANGGTYnnahsiQ 526
Cdd:COG4953 402 NIPAVRLLEALG-------PARFYARLrraglrLLLPPAEhYGLSLILGG--AEVTLEELVGLYAALARGGEA------R 466
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896441666 527 KVVTHEGDTIEYEHT--SHKAmkdytSYMLAEILKGTfKAYGSAYGHGV--SGVNMGAKTGTgTYGqeiYekynlpdnaa 602
Cdd:COG4953 467 PLRLLAGEPASPGRRllSPGA-----AWLVRDILSDV-PRPDGAFGWRAldSPPPIAWKTGT-SYG---F---------- 526
|
570
....*....|....*....
gi 896441666 603 KDVWINGFSPEYTMSVWMG 621
Cdd:COG4953 527 RDAWAVGFTGRYTVGVWVG 545
|
|
| PRK14850 |
PRK14850 |
penicillin-binding protein 1b; Provisional |
62-645 |
3.00e-50 |
|
penicillin-binding protein 1b; Provisional
Pssm-ID: 237835 [Multi-domain] Cd Length: 764 Bit Score: 188.52 E-value: 3.00e-50
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896441666 62 FSESKLDDPIPAKIYDKNGelvktldngQRHEHVNIKDVPKDMKNAVLATEDNRFYQHGALDYKRLFGAIGKNLTGGFGS 141
Cdd:PRK14850 136 FSFLRLDPKLIAMLYSPEG---------KKRLFIPRNQYPEMLIKTLLAIEDKYFYEHDGIHLSSIGRAFLVNLMSGHTI 206
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896441666 142 QGASTLTQQVVKDSFLTQQKSIGRKAQEAYLSYRLEQEYSKDEIFQVYMNKIYY----SDGVTGIKAAAKYYFNKDMKDL 217
Cdd:PRK14850 207 QGGSTLTQQLVKNLFLTNTRSLWRKINEIYMALILDRFYSKDRILELYLNEVYLgqdgNEQIRGFPLASIYYFGRPINEL 286
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896441666 218 NLAEEAYLAGLPQVPNLYNIYNNPKEANNRKDTVLYLMHKHNRINDKQYADAKKIDLKAnlvertkkerQVTGNEKNpEY 297
Cdd:PRK14850 287 NLDQYALLVGMVKGASLYNPWTNPNLTLKRRNLVLFLLYKQKVITRKLYKDLCSRPLNV----------QSKGNIIS-SH 355
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896441666 298 DSYVNFVQSELMNNKYFKDKNLgsvlqSGIKIYTNMDKDVQQTLQDRINNG-----SFYKNEDQQVGATILDSKTGGLVA 372
Cdd:PRK14850 356 PAFIQLVCEEFHKKIHYPFKNF-----SGTKIFTTLDYISQNAAEQAVKIGipilkRKKRLKDLEVAMVIIDRFSGEVRA 430
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896441666 373 ISGGRNyKNVVERNQATDP-HPTGSSLKPFLAYGPAIENMKWSTN--------HVIQDESSYWVDgsqfKNYDTKGHGTV 443
Cdd:PRK14850 431 LIGSSK-PEFNGYNRALKArRSIGSLSKPITYLTALSQPEKYHLNtwisdtpiSIKLDNGQYWTP----KNNNFSFSGKV 505
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896441666 444 SIYDALRQSFNIPALktwqQVKSQAGNDAPQKFASKLGLDySGKIG--PSEVLGGSSseFSPTQLASAFAAIANGGTYNN 521
Cdd:PRK14850 506 MLIDALIHSINIPTV----HLSINLGLKKLVDSWILLGIS-SNYITplPSISLGAIN--LTPMEVAQVFQIIGSGGYKSS 578
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896441666 522 AHSIQKVVTHEGDTI-EYEHTSHKAMKDYTSY-----MLAEILKGTFKAYGSAYghgvSGVNMGAKTGTgtygqeiyeky 595
Cdd:PRK14850 579 LSSIRSIISDDNKVLyQNFPQSKHVESSQASYltlyaMQQVVKSGTAKSLGTIF----KEFSLAGKTGT----------- 643
|
570 580 590 600 610
....*....|....*....|....*....|....*....|....*....|...
gi 896441666 596 nlpDNAAKDVWINGFSPEYTMSVWMGFN---KVKQYGTNSFIghseQDYPQYL 645
Cdd:PRK14850 644 ---TNNLVDSWFVGIDGKQVVITWIGRDnnhTTKLYGSSGAM----KIYKRYL 689
|
|
| mrcB |
PRK09506 |
bifunctional glycosyl transferase/transpeptidase; Reviewed |
88-631 |
5.48e-48 |
|
bifunctional glycosyl transferase/transpeptidase; Reviewed
Pssm-ID: 236544 [Multi-domain] Cd Length: 830 Bit Score: 182.28 E-value: 5.48e-48
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896441666 88 NGQRHEHVNIKDVPKDMKNAVLATEDNRFYQHGALDYKRLFGAIGKNLTGGFGSQGASTLTQQVVKDSFLTQQKSIGRKA 167
Cdd:PRK09506 207 NGEQRLFVPRSGFPDLLVDTLLATEDRHFYEHDGISLYSIGRAVLANLTAGRTVQGGSTLTQQLVKNLFLSNERSLWRKA 286
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896441666 168 QEAYLSYRLEQEYSKDEIFQVYMNKIYY----SDGVTGIKAAAKYYFNKDMKDLNLAEEAYLAGLPQVPNLYNIYNNPKE 243
Cdd:PRK09506 287 NEAYMALIMDARYSKDRILELYLNEVYLgqsgDDQIRGFPLASLYYFGRPVEELSLDQQALLVGMVKGASLYNPWRNPKL 366
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896441666 244 ANNRKDTVLYLMHKHNRINDKQYA--DAKKIDLkanlvertkkerQVTGNEKNPEyDSYVNFVQSELMNNKYFKDKNLgs 321
Cdd:PRK09506 367 ALERRNLVLRLLQQQQIIDQELYDmlSARPLGV------------QPKGGVISPQ-PAFMQMVRQELQAKLGDKVKDL-- 431
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896441666 322 vlqSGIKIYTNMDKDVQQTLQDRINNG-----SFYKNEDQQVGATILDSKTGGLVAISGGRNyKNVVERNQATDP-HPTG 395
Cdd:PRK09506 432 ---SGVKIFTTLDPVSQDAAEKAVEEGipalkKQRKLSDLETAMVVVDRFSGEVRAMVGGSE-PQFAGYNRAMQArRSIG 507
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896441666 396 SSLKPFLAYGPAIENMKWSTNHVIQDE--------SSYWvdgsQFKNYDTKGHGTVSIYDALRQSFNIPALKTWQQVksq 467
Cdd:PRK09506 508 SLAKPATYLTALSQPDKYRLNTWIADApislrqpnGQVW----SPQNDDRRFSGRVMLVDALTRSMNVPTVNLGMAL--- 580
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896441666 468 aGNDAPQKFASKLGLDYS-GKIGPSEVLGGSSseFSPTQLASAFAAIANGGTYNNAHSIQKVVTHEGdTIEYEH--TSHK 544
Cdd:PRK09506 581 -GLPAVTDTWIKLGVPKDqLNPVPAMLLGALN--LTPIEVAQAFQTIASGGNRAPLSALRSVIAEDG-KVLYQSfpQAER 656
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896441666 545 AMKDYTSY-----MLAEILKGTFKAYGSAYGhgvsGVNMGAKTGTgtygqeiyekynlpDNAAKDVWINGFSPEYTMSVW 619
Cdd:PRK09506 657 AVPAQAAYltlytMQQVVQRGTGRQLGAKYP----NLHLAGKTGT--------------TNDLVDSWFAGIDGKEVTITW 718
|
570
....*....|....*
gi 896441666 620 MGFNK---VKQYGTN 631
Cdd:PRK09506 719 VGRDNnqpTKLYGAS 733
|
|
| mrcA |
PRK11636 |
penicillin-binding protein 1a; Provisional |
71-347 |
6.93e-45 |
|
penicillin-binding protein 1a; Provisional
Pssm-ID: 183248 [Multi-domain] Cd Length: 850 Bit Score: 173.01 E-value: 6.93e-45
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896441666 71 IPAKIYDKNGELVKTLDNgQRHEHVNIKDVPKDMKNAVLATEDNRFYQHGALDYKRLFGAIGKNLTGGFGSQGASTLTQQ 150
Cdd:PRK11636 46 TPMQVYSADGELIAQYGE-KRRIPLTLDQIPPEMVKAFIATEDSRFYEHHGVDPVGIFRAASVALFSGHASQGASTITQQ 124
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896441666 151 VVKDSFLTQQKSIGRKAQEAYLSYRLEQEYSKDEIFQVYMNKIYYSDGVTGIKAAAKYYFNKDMKDLNLAEEAYLAGLPQ 230
Cdd:PRK11636 125 LARNFFLSPERTLMRKIKEAFLAIRIEQLLTKDEILELYLNKIYLGYRAYGVGAAAQVYFGKTVDQLTLSEMAVIAGLPK 204
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896441666 231 VPNLYNIYNNPKEANNRKDTVLYLMHKHNRINDKQYADAKKIDLKANLvertkkerqvtgneKNPEYD---SYVNFVQSE 307
Cdd:PRK11636 205 APSTFNPLYSMDRAVARRNVVLSRMLDEGYITQAQYDQARSEPIVANY--------------HAPEIAfsaPYLSEMVRQ 270
|
250 260 270 280
....*....|....*....|....*....|....*....|
gi 896441666 308 LMNNKYFKDknlgsVLQSGIKIYTNMDKDVQQTLQDRINN 347
Cdd:PRK11636 271 EMYNRYGEN-----AYEDGYRVYTTITRKVQQAAQQAVRN 305
|
|
| PRK13481 |
PRK13481 |
glycosyltransferase; Provisional |
90-269 |
7.99e-32 |
|
glycosyltransferase; Provisional
Pssm-ID: 184078 [Multi-domain] Cd Length: 232 Bit Score: 123.76 E-value: 7.99e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896441666 90 QRHEHVNIKDVPKDMKNAVLATEDNRFYQHGALDYKRLFGAIGKNLTGGfGSQGASTLTQQVVKDSFLTQQKSIGRKAQE 169
Cdd:PRK13481 43 NKSSFVSADNMPEYVKGAFISMEDERFYKHHGFDLKGTTRALFSTISDR-DVQGGSTITQQVVKNYFYDNERSFTRKVKE 121
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896441666 170 AYLSYRLEQEYSKDEIFQVYMNKIYYSDGVTGIKAAAKYYF-------NKDMKDLNLAEEAYLAGLPQVPNLYNIYNNPK 242
Cdd:PRK13481 122 LFVAHRVEKQYSKNEILSFYLNNIYFGDNQYTLEGAANHYFgttvnknSTTMSHITVLQSAILASKVNAPSVYNINDMSE 201
|
170 180
....*....|....*....|....*..
gi 896441666 243 EANNRKDTVLYLMHKHNRINDKQYADA 269
Cdd:PRK13481 202 NFTQRVSTNLEKMKQQNYINETQYQQA 228
|
|
| mono_pep_trsgly |
TIGR02070 |
monofunctional biosynthetic peptidoglycan transglycosylase; This family is one of the ... |
91-233 |
3.00e-30 |
|
monofunctional biosynthetic peptidoglycan transglycosylase; This family is one of the transglycosylases involved in the late stages of peptidoglycan biosynthesis. Members tend to be small, about 240 amino acids in length, and consist almost entirely of a domain described by pfam00912 for transglycosylases. Species with this protein will have several other transglycosylases as well. All species with this protein are Proteobacteria that produce murein (peptidoglycan). [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 273951 [Multi-domain] Cd Length: 224 Bit Score: 119.10 E-value: 3.00e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896441666 91 RHEHVNIKDVPKDMKNAVLATEDNRFYQHGALDYKRLFGAIGKNLTGGFGSQGASTLTQQVVKDSFLTQQKSIGRKAQEA 170
Cdd:TIGR02070 54 QHRWRPYDQISPNLKRAVIASEDAKFVEHHGFDWEAIQDALEKNEKSGKVVRGGSTISQQLAKNLFLWSGRSYLRKGLEA 133
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 896441666 171 YLSYRLEQEYSKDEIFQVYMNKIYYSDGVTGIKAAAKYYFNKDMKDLNLAEEAYLAGLpqVPN 233
Cdd:TIGR02070 134 WATWMLETWWSKQRILEVYLNSVEWGNGVFGAEAAARYYFKRSASNLTRGQAARLAAV--LPN 194
|
|
| FtsI |
COG0768 |
Cell division protein FtsI, peptidoglycan transpeptidase (Penicillin-binding protein 2) [Cell ... |
324-618 |
2.24e-28 |
|
Cell division protein FtsI, peptidoglycan transpeptidase (Penicillin-binding protein 2) [Cell cycle control, cell division, chromosome partitioning, Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440531 [Multi-domain] Cd Length: 568 Bit Score: 120.70 E-value: 2.24e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896441666 324 QSGIKIYTNMDKDVQQTLQDRINNGsFYKNEDQQVGATILDSKTGGLVAISG--------GRNYKNVVERNQA-TDPHPT 394
Cdd:COG0768 216 VPGKDLVLTIDSDLQKIAEEALKKA-VEEYKAKSGAVVVMDPKTGEILAMASypsfdpnlFVGGPDEPLRNRAvQGTYEP 294
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896441666 395 GSSLKPFLAYGpAIENMKWSTNHVIQDESSYWVDGSQFKNYDTKGHGTVSIYDALRQSFNIPALKTWQQVksqaGNDAPQ 474
Cdd:COG0768 295 GSTFKPFTAAA-ALEEGVITPDTTFDCPGYYRVGGRTIRDWDRGGHGTLTLTEALAKSSNVGFYKLALRL----GIDKLY 369
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896441666 475 KFASKLGLDYSGKIG-PSEVLG--GSSSEFSPT----------------QLASAFAAIANGGTYNNAHSIQKVVTHEGDT 535
Cdd:COG0768 370 DYLKKFGLGQKTGIDlPGEASGllPSPKRWYPGetatmsigqglsvtplQLAQAYAAIANGGVLVKPHLVKEIVDPDGEV 449
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896441666 536 IEYE-HTSHKAMKDYTSYMLAEILKGTF-KAYGSAYGHGVSGVNMGAKTGTGtygqeiyEKYNLPDNAAKD----VWING 609
Cdd:COG0768 450 VKEEpEVLRRVISPETAETVREGMEGVVnEPGGTARRAAIPGYRVAGKTGTA-------QVVDIGNGGYYKgrhiASFVG 522
|
330
....*....|...
gi 896441666 610 F----SPEYTMSV 618
Cdd:COG0768 523 FapadNPRYAVAV 535
|
|
| Transpeptidase |
pfam00905 |
Penicillin binding protein transpeptidase domain; The active site serine (residue 337 in Swiss: ... |
359-618 |
1.73e-26 |
|
Penicillin binding protein transpeptidase domain; The active site serine (residue 337 in Swiss:P14677) is conserved in all members of this family.
Pssm-ID: 425939 [Multi-domain] Cd Length: 296 Bit Score: 110.20 E-value: 1.73e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896441666 359 GATILDSKTGGLVAISGGRNY----KNVVERNQA-TDPHPTGSSLKPFLAyGPAIENMKWSTNHVIQDESSYWVDGSQFK 433
Cdd:pfam00905 2 SAVVLDPKTGEVLAMVGKPSYdpngFIGPLRNRAvTSRYEPGSTFKPFTA-LAALDNGVLKPDETIFDWPGKQQGGKSIG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896441666 434 NYDTKGHGTVSIYDALRQSFNIPALKTWQQVKSQAGNDAPQKF--ASKLGLDYSGKIG---PSEVLGGSSSEF------S 502
Cdd:pfam00905 81 DWNQDQVGIGTLRQALEYSSNWYMQKLAQKLGADKLRSYLKKFgyGNKTGIGLPGENAgylTPYWLEGATASFgigltiT 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896441666 503 PTQLASAFAAIANGGTYNNAHSIQKVVthegDTIEYEHTSHKAMKDYTSYMLAEILKGTFKAYGSAYGHGVSGVNMGAKT 582
Cdd:pfam00905 161 PLQQAQAYAAIANGGKLVPPHLVKSIE----DKVDPKVLNKLPISKSTAEKVKDMLRLVVNDGTGTGTAAVPGYKVAGKT 236
|
250 260 270 280
....*....|....*....|....*....|....*....|
gi 896441666 583 GTgtyGQEIYEKYNLPDNAAKDVWINGFS----PEYTMSV 618
Cdd:pfam00905 237 GT---AQVAGPKGGGYYDGAQIGWFVGYApadnPKYAFAV 273
|
|
| PRK11240 |
PRK11240 |
penicillin-binding protein 1C; Provisional |
95-621 |
5.55e-23 |
|
penicillin-binding protein 1C; Provisional
Pssm-ID: 183049 [Multi-domain] Cd Length: 772 Bit Score: 104.78 E-value: 5.55e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896441666 95 VNIKDVPKDMKNAVLATEDNRFYQHGALDYKRLFGAIGKNLTGGFGSQGASTLTQQVVK------DSFLTQQKSIGRKAQ 168
Cdd:PRK11240 65 VTIEDVSPRYLEALINYEDRWFWKHPGVNPFSVARAAWQDLTSGRVISGGSTLTMQVARlldphpRTFGGKIRQLWRALQ 144
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896441666 169 eaylsyrLEQEYSKDEIFQVYMNKIYYSDGVTGIKAAAKYYFNKDMKDLNLAEEAYLAGLPQVPNLYNIYNNPKEANNRK 248
Cdd:PRK11240 145 -------LEWHLSKREILTLYLNRAPFGGTLQGIGAASWAYLGKSPANLSYAEAALLAVLPQAPSRLRPDRWPERAEAAR 217
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896441666 249 DTVLYLMHKHNRINDKQYADAKKIDLKAnlvertkKERQVtgneknPEYDSYVnfvqSELMNNKYFKDknlgsvlqsgiK 328
Cdd:PRK11240 218 NKVLERMAEQGVWSAEQVKESREEPVWL-------APRQM------PQLAPLF----ARMMLGKSKSD-----------K 269
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896441666 329 IYTNMDKDVQQTLQDRINNGSFYKNEDQQVGATILDSKTG------GLVAISGGRNYKNVVERNQATDPhptGSSLKPFL 402
Cdd:PRK11240 270 IVTTLDAGLQRRLEDLALNWKGRLPPRSSLAMIVVDHTDMavrgwvGSVDLNDDSRFGHVDMVNAIRSP---GSVLKPFV 346
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896441666 403 aYGPAIENMKWSTNHVIQD---ESSYWVDGsqfkNYDTKGHGTVSIYDALRQSFNIPALktwqQVKSQAGndaPQKFASK 479
Cdd:PRK11240 347 -YGLALDDGLIHPASLLQDvprRTGDYRPG----NFDSGFHGPVSMSEALVRSLNLPAV----QVLEAYG---PKRFAAK 414
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896441666 480 L---GLDYSGKIGP----SEVLGGSSSEFSptQLASAFAAIANGGtynnahSIQKVVTHEGDTIeyehTSHKAMKDYTSY 552
Cdd:PRK11240 415 LrnvGLPLYLPAGAepnlSLILGGAGARLE--DMVAAYSAFARHG------KAAKLRLQPDDPL----LERPLMSPGAAW 482
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 896441666 553 MLAEILKGtfKAYGSAYGHGVSGVNMGAKTGTgTYGqeiYekynlpdnaaKDVWINGFSPEYTMSVWMG 621
Cdd:PRK11240 483 IIRRIMAD--EAQPLPDAALPRVVPLAWKTGT-SYG---Y----------RDAWAIGVNARYVIGIWTG 535
|
|
| pbp2_mrdA |
TIGR03423 |
penicillin-binding protein 2; Members of this protein family are penicillin-binding protein 2 ... |
324-618 |
2.96e-13 |
|
penicillin-binding protein 2; Members of this protein family are penicillin-binding protein 2 (PBP-2), a protein whose gene (designated pbpA or mrdA) generally is found next to the gene for RodA, a protein required for rod (bacillus) shape in many bacteria. PBP-2 acts as a transpeptidase for cell elongation (hence, rod-shape). [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 274573 [Multi-domain] Cd Length: 592 Bit Score: 72.94 E-value: 2.96e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896441666 324 QSGIKIYTNMDKDVQQTLQDRInngsfyknEDQQVGATILDSKTGGLVA---------------ISGgRNYKNVVE---- 384
Cdd:TIGR03423 223 VPGKDLVLTIDARLQQAAEKAL--------GGRRGAVVVMDPRTGEILAmvstpsfdpnlfvdgISS-KDYKALLNdpdr 293
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896441666 385 --RNQATDPH-PTGSSLKPFLAyGPAIENMKWSTNHVIQDESSYWVDGSQFKNYDTKGHGTVSIYDALRQSFNipalkTW 461
Cdd:TIGR03423 294 plLNRAIQGVyPPGSTFKPVVA-LAALEEGVITPETRIYCPGYFQLGGRRFRCWKRGGHGRVDLRKAIEESCD-----VY 367
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896441666 462 -QQVKSQAGNDAPQKFASKLGL-DYSGKIGPSEVLG------------------GSSSEFS---------PTQLASAFAA 512
Cdd:TIGR03423 368 fYQLALRLGIDKIAEYAKRFGFgQKTGIDLPGEKSGlvpsrewkrkrfgqpwypGDTLNVSigqgyvlvtPLQLAVATAA 447
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896441666 513 IANGGTYNNAHSIQKVVTHEGDTIEYEHTSHKAMKDYTSYMLAEILKGTF----KAYGSAYGHGV-SGVNMGAKTGTG-T 586
Cdd:TIGR03423 448 LANGGKLYKPHLVKSIEDPDGGVVRRTEPEVLRPLPISPENLDVVREGMRdvvnGPGGTARRARLgLPYKMAGKTGTAqV 527
|
330 340 350 360
....*....|....*....|....*....|....*....|...
gi 896441666 587 YGQEIYEKYN-------LPDNAakdvWINGF----SPEYTMSV 618
Cdd:TIGR03423 528 VSLKQGEKYDaeqiperLRDHA----LFVAFapydNPKIAVAV 566
|
|
|