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Conserved domains on  [gi|894108564|emb|COK44713|]
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site-specific recombinase%2C resolvase family protein [Streptococcus pneumoniae]

Protein Classification

recombinase family protein( domain architecture ID 10085488)

recombinase family protein is a serine recombinase that catalyzes the site-specific recombination of DNA molecules by a concerted, four-strand cleavage and rejoining mechanism which involves a transient phosphoserine linkage between DNA and the enzyme

CATH:  3.40.50.1390
Gene Ontology:  GO:0000150|GO:0003677|GO:0006310|GO:0015074
PubMed:  21645851|26104451|11972771|16077726|9348666
SCOP:  3000065

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Ser_Recombinase cd00338
Serine Recombinase family, catalytic domain; a DNA binding domain may be present either N- or ...
 10-139 9.92e-39

Serine Recombinase family, catalytic domain; a DNA binding domain may be present either N- or C-terminal to the catalytic domain. These enzymes perform site-specific recombination of DNA molecules by a concerted, four-strand cleavage and rejoining mechanism which involves a transient phosphoserine linkage between DNA and serine recombinase. Serine recombinases demonstrate functional versatility and include resolvases, invertases, integrases, and transposases. Resolvases and invertases (i.e. Tn3, gamma-delta, Tn5044 resolvases, Gin and Hin invertases) in this family contain a C-terminal DNA binding domain and comprise a major phylogenic group. Also included are phage- and bacterial-encoded recombinases such as phiC31 integrase, SpoIVCA excisionase, and Tn4451 TnpX transposase. These integrases and transposases have larger C-terminal domains compared to resolvases/invertases and are referred to as large serine recombinases. Also belonging to this family are proteins with N-terminal DNA binding domains similar to IS607- and IS1535-transposases from Helicobacter and Mycobacterium.


:

Pssm-ID: 238206 [Multi-domain]  Cd Length: 137  Bit Score: 132.77  E-value: 9.92e-39
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 894108564  10 LYTRVSTSIQIEGYSLEAQKSRMKAFAIYNDYEIVGEYEDAGKSGKSIEGRIQFNRMMEDIKSGKdgVSFVLVFKLSRFA 89
Cdd:cd00338    1 IYARVSTDKQEQGDSLERQREALREYAARNGLEVVGEYEDAGSSATSLVDRPGLQRLLADVKAGK--IDVVLVEKLDRLS 78

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|
gi 894108564  90 RNAADVLSTLQIMQDYGVNLICVEDGIDSSKDAGKLMISVLSAVAEIERE 139
Cdd:cd00338   79 RNLVDLLELLELLEAHGVRVVTADGEIDLDSEDGRLMLGILAAMAEEESK 128
Smc super family cl34174
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 131-210 8.30e-03

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


The actual alignment was detected with superfamily member COG1196:

Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 37.61  E-value: 8.30e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 894108564 131 SAVAEIEREIDNYQKELRKSHSTKFKLIEEIDNLDVEDKHYKRRKQDLDDRLYRMYDKLDELESSLIDAKAKKQTIEAEK 210
Cdd:COG1196  267 AELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEEL 346
 
Name Accession Description Interval E-value
Ser_Recombinase cd00338
Serine Recombinase family, catalytic domain; a DNA binding domain may be present either N- or ...
 10-139 9.92e-39

Serine Recombinase family, catalytic domain; a DNA binding domain may be present either N- or C-terminal to the catalytic domain. These enzymes perform site-specific recombination of DNA molecules by a concerted, four-strand cleavage and rejoining mechanism which involves a transient phosphoserine linkage between DNA and serine recombinase. Serine recombinases demonstrate functional versatility and include resolvases, invertases, integrases, and transposases. Resolvases and invertases (i.e. Tn3, gamma-delta, Tn5044 resolvases, Gin and Hin invertases) in this family contain a C-terminal DNA binding domain and comprise a major phylogenic group. Also included are phage- and bacterial-encoded recombinases such as phiC31 integrase, SpoIVCA excisionase, and Tn4451 TnpX transposase. These integrases and transposases have larger C-terminal domains compared to resolvases/invertases and are referred to as large serine recombinases. Also belonging to this family are proteins with N-terminal DNA binding domains similar to IS607- and IS1535-transposases from Helicobacter and Mycobacterium.


Pssm-ID: 238206 [Multi-domain]  Cd Length: 137  Bit Score: 132.77  E-value: 9.92e-39
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 894108564  10 LYTRVSTSIQIEGYSLEAQKSRMKAFAIYNDYEIVGEYEDAGKSGKSIEGRIQFNRMMEDIKSGKdgVSFVLVFKLSRFA 89
Cdd:cd00338    1 IYARVSTDKQEQGDSLERQREALREYAARNGLEVVGEYEDAGSSATSLVDRPGLQRLLADVKAGK--IDVVLVEKLDRLS 78

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|
gi 894108564  90 RNAADVLSTLQIMQDYGVNLICVEDGIDSSKDAGKLMISVLSAVAEIERE 139
Cdd:cd00338   79 RNLVDLLELLELLEAHGVRVVTADGEIDLDSEDGRLMLGILAAMAEEESK 128
SpoIVCA COG1961
Site-specific DNA recombinase SpoIVCA/DNA invertase PinE [Replication, recombination and ...
 5-140 1.51e-38

Site-specific DNA recombinase SpoIVCA/DNA invertase PinE [Replication, recombination and repair];


Pssm-ID: 441564 [Multi-domain]  Cd Length: 388  Bit Score: 139.77  E-value: 1.51e-38
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 894108564   5 KIKVYLYTRVSTSIQiEGYSLEAQKSRMKAFAIYNDYEIVGEYEDAGKSGKSIEgRIQFNRMMEDIKSGKDGVsfVLVFK 84
Cdd:COG1961    1 MMRAAGYARVSTDDQ-EGLSLERQREALRAYAEKAGWEIVRIYVDEGVSGTSKD-RPGLQRLLADLRAGKFDT--LVVWK 76

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 894108564  85 LSRFARNAADVLSTLQIMQDYGVNLICVEDGIDSSKDAGKLMISVLSAVAEIEREI 140
Cdd:COG1961   77 LDRLGRNLADLLELVEELKERGVRLISLTEGIDTSTPMGRLLLTILAAFAEFEREL 132
Resolvase smart00857
Resolvase, N terminal domain; The N-terminal domain of the resolvase family contains the ...
 8-140 4.02e-36

Resolvase, N terminal domain; The N-terminal domain of the resolvase family contains the active site and the dimer interface. The extended arm at the C-terminus of this domain connects to the C-terminal helix-turn-helix domain of resolvase.


Pssm-ID: 214861 [Multi-domain]  Cd Length: 148  Bit Score: 126.58  E-value: 4.02e-36
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 894108564     8 VYLYTRVSTSIQIEGySLEAQKSRMKAFAIYNDYEIVGEYEDAGKSGKSIEgRIQFNRMMEDIKSGKDGVsfVLVFKLSR 87
Cdd:smart00857   1 AAGYARVSTDDQADG-SLERQLEALRAYAERNGWEVVRIYEDEGVSGKKAD-RPGLQRLLADLRAGDIDV--LVVYKLDR 76

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|....
gi 894108564    88 FARNAADVLSTLQIMQDYGVNLICVEDGI-DSSKDAGKLMISVLSAVAEIEREI 140
Cdd:smart00857  77 LGRSLRDLLALLELLEEKGVRLVSLKEGIlDTSTPAGRLLLDILAALAEFEREL 130
Resolvase pfam00239
Resolvase, N terminal domain; The N-terminal domain of the resolvase family (this family) ...
 8-140 3.67e-32

Resolvase, N terminal domain; The N-terminal domain of the resolvase family (this family) contains the active site and the dimer interface. The extended arm at the C-terminus of this domain connects to the C-terminal helix-turn-helix domain of resolvase - see pfam02796.


Pssm-ID: 425548 [Multi-domain]  Cd Length: 144  Bit Score: 116.22  E-value: 3.67e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 894108564    8 VYLYTRVSTSIQieGYSLEAQKSRMKAFAIYNDyeIVGEYEDAGKSGKSIEgRIQFNRMMEDIKSGKDGVsfVLVFKLSR 87
Cdd:pfam00239   1 AIGYARVSTEDQ--DDSLERQLEALRAYAACNG--KIVEFEDKGVSGRKLD-RPGLQRLLALLRAGKGDV--LVVYKLDR 73

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|...
gi 894108564   88 FARNAADVLSTLQIMQDYGVNLICVEDGIDSSKDAGKLMISVLSAVAEIEREI 140
Cdd:pfam00239  74 LGRSLRDLLTLVEELREKGVDLVSLDEGIDTSTPMGRLLLTILAALAEFERAL 126
mpi PRK13413
master DNA invertase Mpi family serine-type recombinase;
8-138 3.19e-03

master DNA invertase Mpi family serine-type recombinase;


Pssm-ID: 184041 [Multi-domain]  Cd Length: 200  Bit Score: 37.77  E-value: 3.19e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 894108564   8 VYLYTRVSTSIQiegySLEAQKSRMKAFAIYNDYEIVGEYEDAGKSGKSIEGRiQFNRMMEDIKSGkdgvSFVLVFKLSR 87
Cdd:PRK13413   2 IYAYIRVSTDKQ----TVENQRFEITNFAEKNNLTIDKWIEETISGTKSYKDR-KLGKLLKKMRKG----DILIVSELSR 72

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|..
gi 894108564  88 FARNAADVLSTLQIMQDYGVNLICVEDGIDSSKD-AGKLMISVLSAVAEIER 138
Cdd:PRK13413  73 LGRNLMEIMSILNICMEKEVIVYTIKEGYELGDDiNSKVLAFAFGLSAEIER 124
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 131-210 8.30e-03

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 37.61  E-value: 8.30e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 894108564 131 SAVAEIEREIDNYQKELRKSHSTKFKLIEEIDNLDVEDKHYKRRKQDLDDRLYRMYDKLDELESSLIDAKAKKQTIEAEK 210
Cdd:COG1196  267 AELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEEL 346
 
Name Accession Description Interval E-value
Ser_Recombinase cd00338
Serine Recombinase family, catalytic domain; a DNA binding domain may be present either N- or ...
 10-139 9.92e-39

Serine Recombinase family, catalytic domain; a DNA binding domain may be present either N- or C-terminal to the catalytic domain. These enzymes perform site-specific recombination of DNA molecules by a concerted, four-strand cleavage and rejoining mechanism which involves a transient phosphoserine linkage between DNA and serine recombinase. Serine recombinases demonstrate functional versatility and include resolvases, invertases, integrases, and transposases. Resolvases and invertases (i.e. Tn3, gamma-delta, Tn5044 resolvases, Gin and Hin invertases) in this family contain a C-terminal DNA binding domain and comprise a major phylogenic group. Also included are phage- and bacterial-encoded recombinases such as phiC31 integrase, SpoIVCA excisionase, and Tn4451 TnpX transposase. These integrases and transposases have larger C-terminal domains compared to resolvases/invertases and are referred to as large serine recombinases. Also belonging to this family are proteins with N-terminal DNA binding domains similar to IS607- and IS1535-transposases from Helicobacter and Mycobacterium.


Pssm-ID: 238206 [Multi-domain]  Cd Length: 137  Bit Score: 132.77  E-value: 9.92e-39
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 894108564  10 LYTRVSTSIQIEGYSLEAQKSRMKAFAIYNDYEIVGEYEDAGKSGKSIEGRIQFNRMMEDIKSGKdgVSFVLVFKLSRFA 89
Cdd:cd00338    1 IYARVSTDKQEQGDSLERQREALREYAARNGLEVVGEYEDAGSSATSLVDRPGLQRLLADVKAGK--IDVVLVEKLDRLS 78

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|
gi 894108564  90 RNAADVLSTLQIMQDYGVNLICVEDGIDSSKDAGKLMISVLSAVAEIERE 139
Cdd:cd00338   79 RNLVDLLELLELLEAHGVRVVTADGEIDLDSEDGRLMLGILAAMAEEESK 128
SpoIVCA COG1961
Site-specific DNA recombinase SpoIVCA/DNA invertase PinE [Replication, recombination and ...
 5-140 1.51e-38

Site-specific DNA recombinase SpoIVCA/DNA invertase PinE [Replication, recombination and repair];


Pssm-ID: 441564 [Multi-domain]  Cd Length: 388  Bit Score: 139.77  E-value: 1.51e-38
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 894108564   5 KIKVYLYTRVSTSIQiEGYSLEAQKSRMKAFAIYNDYEIVGEYEDAGKSGKSIEgRIQFNRMMEDIKSGKDGVsfVLVFK 84
Cdd:COG1961    1 MMRAAGYARVSTDDQ-EGLSLERQREALRAYAEKAGWEIVRIYVDEGVSGTSKD-RPGLQRLLADLRAGKFDT--LVVWK 76

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 894108564  85 LSRFARNAADVLSTLQIMQDYGVNLICVEDGIDSSKDAGKLMISVLSAVAEIEREI 140
Cdd:COG1961   77 LDRLGRNLADLLELVEELKERGVRLISLTEGIDTSTPMGRLLLTILAAFAEFEREL 132
Resolvase smart00857
Resolvase, N terminal domain; The N-terminal domain of the resolvase family contains the ...
 8-140 4.02e-36

Resolvase, N terminal domain; The N-terminal domain of the resolvase family contains the active site and the dimer interface. The extended arm at the C-terminus of this domain connects to the C-terminal helix-turn-helix domain of resolvase.


Pssm-ID: 214861 [Multi-domain]  Cd Length: 148  Bit Score: 126.58  E-value: 4.02e-36
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 894108564     8 VYLYTRVSTSIQIEGySLEAQKSRMKAFAIYNDYEIVGEYEDAGKSGKSIEgRIQFNRMMEDIKSGKDGVsfVLVFKLSR 87
Cdd:smart00857   1 AAGYARVSTDDQADG-SLERQLEALRAYAERNGWEVVRIYEDEGVSGKKAD-RPGLQRLLADLRAGDIDV--LVVYKLDR 76

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|....
gi 894108564    88 FARNAADVLSTLQIMQDYGVNLICVEDGI-DSSKDAGKLMISVLSAVAEIEREI 140
Cdd:smart00857  77 LGRSLRDLLALLELLEEKGVRLVSLKEGIlDTSTPAGRLLLDILAALAEFEREL 130
Resolvase pfam00239
Resolvase, N terminal domain; The N-terminal domain of the resolvase family (this family) ...
 8-140 3.67e-32

Resolvase, N terminal domain; The N-terminal domain of the resolvase family (this family) contains the active site and the dimer interface. The extended arm at the C-terminus of this domain connects to the C-terminal helix-turn-helix domain of resolvase - see pfam02796.


Pssm-ID: 425548 [Multi-domain]  Cd Length: 144  Bit Score: 116.22  E-value: 3.67e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 894108564    8 VYLYTRVSTSIQieGYSLEAQKSRMKAFAIYNDyeIVGEYEDAGKSGKSIEgRIQFNRMMEDIKSGKDGVsfVLVFKLSR 87
Cdd:pfam00239   1 AIGYARVSTEDQ--DDSLERQLEALRAYAACNG--KIVEFEDKGVSGRKLD-RPGLQRLLALLRAGKGDV--LVVYKLDR 73

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|...
gi 894108564   88 FARNAADVLSTLQIMQDYGVNLICVEDGIDSSKDAGKLMISVLSAVAEIEREI 140
Cdd:pfam00239  74 LGRSLRDLLTLVEELREKGVDLVSLDEGIDTSTPMGRLLLTILAALAEFERAL 126
SR_ResInv cd03768
Serine Recombinase (SR) family, Resolvase and Invertase subfamily, catalytic domain; members ...
 8-140 6.37e-28

Serine Recombinase (SR) family, Resolvase and Invertase subfamily, catalytic domain; members contain a C-terminal DNA binding domain. Serine recombinases catalyze site-specific recombination of DNA molecules by a concerted, four-strand cleavage and rejoining mechanism which involves a transient phosphoserine linkage between DNA and the enzyme. They are functionally versatile and include resolvases, invertases, integrases, and transposases. Resolvases and invertases affect resolution or inversion and comprise a major phylogenic group. Resolvases (e.g. Tn3, gamma-delta, and Tn5044) normally recombine two sites in direct repeat causing deletion of the DNA between the sites. Invertases (e.g. Gin and Hin) recombine sites in inverted repeat to invert the DNA between the sites. Cointegrate resolution with gamma-delta resolvase requires the formation of a synaptosome of three resolvase dimers bound to each of two res sites on the DNA. Also included in this subfamily are some putative integrases including a sequence from bacteriophage phi-FC1.


Pssm-ID: 239737 [Multi-domain]  Cd Length: 126  Bit Score: 104.48  E-value: 6.37e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 894108564   8 VYLYTRVSTsiqiEGYSLEAQKSRMKAFAiyndyEIVGEYEDAGKSGKsiEGRIQFNRMMEDIKSGkDGVsfvLVFKLSR 87
Cdd:cd03768    1 VIGYARVST----DDQSLERQLEALKAAG-----ECDKIFEEKGSGGK--KERPELQKLLEDLREG-DTL---VVTKLDR 65

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|...
gi 894108564  88 FARNAADVLSTLQIMQDYGVNLICVEDGIDSSKDAGKLMISVLSAVAEIEREI 140
Cdd:cd03768   66 LGRSTKDLLEIVEELREKGVSLRSLTEGIDTSTPSGKLMLTILGAFAEFEREL 118
SR_TndX_transposase cd03770
Serine Recombinase (SR) family, TndX-like transposase subfamily, catalytic domain; composed of ...
 8-121 5.14e-14

Serine Recombinase (SR) family, TndX-like transposase subfamily, catalytic domain; composed of large serine recombinases similar to Clostridium TndX and TnpX transposases. Serine recombinases catalyze site-specific recombination of DNA molecules by a concerted, four-strand cleavage and rejoining mechanism which involves a transient phosphoserine linkage between DNA and the enzyme. They are functionally versatile and include resolvases, invertases, integrases, and transposases. TndX mediates the excision and circularization of the conjugative transposon Tn5397 from Clostridium difficile. TnpX is responsible for the movement of the nonconjugative chloramphenicol resistance elements of the Tn4451/3 family. Mobile genetic elements such as transposons are important vehicles for the transmission of virulence and antibiotic resistance in many microorganisms.


Pssm-ID: 239739 [Multi-domain]  Cd Length: 140  Bit Score: 67.78  E-value: 5.14e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 894108564   8 VYLYTRVSTS--IQIEGYSLEAQKSRMKAFAIYNDYEIVGEYEDAGKSGKSIEgRIQFNRMMEDIKSGKdgVSFVLVFKL 85
Cdd:cd03770    1 TALYCRLSRDddLDGESNSIENQKAILEEYAKENGLENIRHYIDDGFSGTTFD-RPGFNRMIEDIEAGK--IDIVIVKDM 77

                         90       100       110
                 ....*....|....*....|....*....|....*..
gi 894108564  86 SRFARNAADVLSTLQIM-QDYGVNLICVEDGIDSSKD 121
Cdd:cd03770   78 SRLGRNYLKVGLYMEILfPKKGVRFIAINDGVDSADG 114
SR_IS607_transposase_like cd03769
Serine Recombinase (SR) family, IS607-like transposase subfamily, catalytic domain; members ...
 8-121 1.73e-04

Serine Recombinase (SR) family, IS607-like transposase subfamily, catalytic domain; members contain a DNA binding domain with homology to MerR/SoxR located N-terminal to the catalytic domain. Serine recombinases catalyze site-specific recombination of DNA molecules by a concerted, four-strand cleavage and rejoining mechanism which involves a transient phosphoserine linkage between DNA and the enzyme. They are functionally versatile and include resolvases, invertases, integrases, and transposases. This subfamily is composed of proteins that catalyze the transposition of insertion sequence (IS) elements such as IS607 from Helicobacter and IS1535 from Mycobacterium, and similar proteins from other bacteria and several archaeal species. IS elements are DNA segments that move to new sites in prokaryotic and eukaryotic genomes causing insertion mutations and gene rearrangements.


Pssm-ID: 239738  Cd Length: 134  Bit Score: 40.71  E-value: 1.73e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 894108564   8 VYLYTRVSTSIQIEGysLEAQKSRMKAFAIYNdYEIVGEYEDAGkSGKSiEGRIQFNRMMEDIKSGKdgVSFVLVFKLSR 87
Cdd:cd03769    1 TVLYARVSSHDQKDD--LERQIERLEAYATAQ-GWIVEVIKDIG-SGLN-EKRKGLLKLLEDVLAGK--VERVVITYKDR 73

                         90       100       110
                 ....*....|....*....|....*....|....
gi 894108564  88 FARNAADVLSTLqiMQDYGVNLICVEDGIDSSKD 121
Cdd:cd03769   74 LARFGFELLEEL--FKAYGVEIVVINQEENEELE 105
mpi PRK13413
master DNA invertase Mpi family serine-type recombinase;
8-138 3.19e-03

master DNA invertase Mpi family serine-type recombinase;


Pssm-ID: 184041 [Multi-domain]  Cd Length: 200  Bit Score: 37.77  E-value: 3.19e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 894108564   8 VYLYTRVSTSIQiegySLEAQKSRMKAFAIYNDYEIVGEYEDAGKSGKSIEGRiQFNRMMEDIKSGkdgvSFVLVFKLSR 87
Cdd:PRK13413   2 IYAYIRVSTDKQ----TVENQRFEITNFAEKNNLTIDKWIEETISGTKSYKDR-KLGKLLKKMRKG----DILIVSELSR 72

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|..
gi 894108564  88 FARNAADVLSTLQIMQDYGVNLICVEDGIDSSKD-AGKLMISVLSAVAEIER 138
Cdd:PRK13413  73 LGRNLMEIMSILNICMEKEVIVYTIKEGYELGDDiNSKVLAFAFGLSAEIER 124
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 131-210 8.30e-03

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 37.61  E-value: 8.30e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 894108564 131 SAVAEIEREIDNYQKELRKSHSTKFKLIEEIDNLDVEDKHYKRRKQDLDDRLYRMYDKLDELESSLIDAKAKKQTIEAEK 210
Cdd:COG1196  267 AELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEEL 346
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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