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Conserved domains on  [gi|88789064|gb|EAR20203|]
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Enoyl-CoA hydratase/isomerase [Nitrococcus mobilis Nb-231]

Protein Classification

Clp protease/crotonase-like domain-containing protein( domain architecture ID 581041)

Clp protease/crotonase-like domain-containing protein similar to Oryza sativa enoyl-CoA delta isomerase which plays a role in fatty acid metabolism, which involves stabilization of an enolate anion intermediate derived from an acyl-CoA substrate

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
crotonase-like super family cl23717
Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse ...
1-260 3.76e-99

Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase. Many of these play important roles in fatty acid metabolism. In addition to a conserved structural core and the formation of trimers (or dimers of trimers), a common feature in this superfamily is the stabilization of an enolate anion intermediate derived from an acyl-CoA substrate. This is accomplished by two conserved backbone NH groups in active sites that form an oxyanion hole.


The actual alignment was detected with superfamily member PRK05995:

Pssm-ID: 474030 [Multi-domain]  Cd Length: 262  Bit Score: 290.29  E-value: 3.76e-99
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064    1 MQTKRLITMIEGAVARLTLNRPEVHNAFDDRLIEELTGALERFEQDQRLRLVILNATGTSFSAGADLNWMRRTAAYSWEE 80
Cdd:PRK05995   1 MMYETLEIEQRGQVATVTLNRPDVRNAFNETVIAELTAAFRALDADDSVRAVVLAGAGKAFCAGADLNWMKKMAGYSDDE 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064   81 NFADAQRLGRLMQMLDQLALPTLVQIHGAALGGGVGLVAACDIAVAADSAFFALAEVKLGLIPAVISPYVIRAIGARAAR 160
Cdd:PRK05995  81 NRADARRLADMLRAIYRCPKPVIARVHGDAYAGGMGLVAACDIAVAADHAVFCLSEVRLGLIPATISPYVIRAMGERAAR 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064  161 RYFLTGERITAQQALRLGLVHEVVPDKQLDDRLAELAQTLLGNGPQAVRAAKRLIRTAGRDAIDASLIDETARRIAEQRA 240
Cdd:PRK05995 161 RYFLTAERFDAAEALRLGLVHEVVPAEALDAKVDELLAALVANSPQAVRAGKRLVRDVAGRPIDAALIADTASRIALIRA 240
                        250       260
                 ....*....|....*....|
gi 88789064  241 SAEAKEGVAAFLEKRKPDWR 260
Cdd:PRK05995 241 TEEAREGVAAFLEKRKPAWR 260
 
Name Accession Description Interval E-value
PRK05995 PRK05995
enoyl-CoA hydratase; Provisional
1-260 3.76e-99

enoyl-CoA hydratase; Provisional


Pssm-ID: 235664 [Multi-domain]  Cd Length: 262  Bit Score: 290.29  E-value: 3.76e-99
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064    1 MQTKRLITMIEGAVARLTLNRPEVHNAFDDRLIEELTGALERFEQDQRLRLVILNATGTSFSAGADLNWMRRTAAYSWEE 80
Cdd:PRK05995   1 MMYETLEIEQRGQVATVTLNRPDVRNAFNETVIAELTAAFRALDADDSVRAVVLAGAGKAFCAGADLNWMKKMAGYSDDE 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064   81 NFADAQRLGRLMQMLDQLALPTLVQIHGAALGGGVGLVAACDIAVAADSAFFALAEVKLGLIPAVISPYVIRAIGARAAR 160
Cdd:PRK05995  81 NRADARRLADMLRAIYRCPKPVIARVHGDAYAGGMGLVAACDIAVAADHAVFCLSEVRLGLIPATISPYVIRAMGERAAR 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064  161 RYFLTGERITAQQALRLGLVHEVVPDKQLDDRLAELAQTLLGNGPQAVRAAKRLIRTAGRDAIDASLIDETARRIAEQRA 240
Cdd:PRK05995 161 RYFLTAERFDAAEALRLGLVHEVVPAEALDAKVDELLAALVANSPQAVRAGKRLVRDVAGRPIDAALIADTASRIALIRA 240
                        250       260
                 ....*....|....*....|
gi 88789064  241 SAEAKEGVAAFLEKRKPDWR 260
Cdd:PRK05995 241 TEEAREGVAAFLEKRKPAWR 260
CaiD COG1024
Enoyl-CoA hydratase/carnithine racemase [Lipid transport and metabolism]; Enoyl-CoA hydratase ...
10-256 3.24e-64

Enoyl-CoA hydratase/carnithine racemase [Lipid transport and metabolism]; Enoyl-CoA hydratase/carnithine racemase is part of the Pathway/BioSystem: Fatty acid biosynthesis


Pssm-ID: 440647 [Multi-domain]  Cd Length: 249  Bit Score: 200.78  E-value: 3.24e-64
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064  10 IEGAVARLTLNRPEVHNAFDDRLIEELTGALERFEQDQRLRLVILNATGTSFSAGADLNWMRRTAAYswEENFADAQRLG 89
Cdd:COG1024   5 REGGVATITLNRPEKLNALSLEMLAELAAALDEAEADPDVRVVVLTGAGKAFCAGADLKELAAAADP--EEARAFARGLQ 82
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064  90 RLMQMLDQLALPTLVQIHGAALGGGVGLVAACDIAVAADSAFFALAEVKLGLIPAVISPYVIRAIG-ARAARRYFLTGER 168
Cdd:COG1024  83 RLFRALRRLPKPVIAAVNGAALGGGLELALACDLRIAAEDARFGLPEVRLGLIPGGGGTQRLPRLVgLARAKELLLTGRR 162
                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064 169 ITAQQALRLGLVHEVVPDKQLDDRLAELAQTLLGNGPQAVRAAKRLIRTAGRDAIDASLiDETARRIAEQRASAEAKEGV 248
Cdd:COG1024 163 IDAEEALELGLVNRVVPDDELLAAALALAARLAAGPPLALAATKRALNAALEAPLDEAL-ELEAEAFAELFASEDAREGI 241

                ....*...
gi 88789064 249 AAFLEKRK 256
Cdd:COG1024 242 AAFLEKRK 249
ECH_1 pfam00378
Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: ...
10-260 2.16e-43

Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: enoyl-CoA hydratase, napthoate synthase, carnitate racemase, 3-hydroxybutyryl-CoA dehydratase and dodecanoyl-CoA delta-isomerase.


Pssm-ID: 395302 [Multi-domain]  Cd Length: 251  Bit Score: 147.51  E-value: 2.16e-43
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064    10 IEGAVARLTLNRPEVHNAFDDRLIEELTGALERFEQDQRLRLVILNATGTSFSAGADLNWM----RRTAAYSWEENFAda 85
Cdd:pfam00378   2 INAGVAVITLNRPEAVNALSAELITELIQALEKLRTDPSVRAVVLTGGDKAFCAGADLKEMygegPAHQALYRENVLD-- 79
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064    86 qrlgrLMQMLDQLALPTLVQIHGAALGGGVGLVAACDIAVAADSAFFALAEVKLGLIP-AVISPYVIRAIGARAARRYFL 164
Cdd:pfam00378  80 -----LWTLLYTCPKPVIAAVNGYAIGGGCELALACDIIIAADNASFGLNETKLGIIPgAGGTDRLPRIIGHSKAMEMLL 154
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064   165 TGERITAQQALRLGLVHEVVPDKQLDDRLAELAQTLLGNGPQAVRAAKRLIRTAGRDAidaslidETARRIAEQR----- 239
Cdd:pfam00378 155 LGRRISAQEALKWGLVDKVVPEDQLLDEARELAEKLAEKSPAALAQLKKALNAKLEDA-------LPTQLEAEARlfyst 227
                         250       260
                  ....*....|....*....|..
gi 88789064   240 -ASAEAKEGVAAFLEKRKPDWR 260
Cdd:pfam00378 228 fSKDDIIEGLQAFLEKRKPPWE 249
crotonase-like cd06558
Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse ...
10-200 1.45e-42

Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase. Many of these play important roles in fatty acid metabolism. In addition to a conserved structural core and the formation of trimers (or dimers of trimers), a common feature in this superfamily is the stabilization of an enolate anion intermediate derived from an acyl-CoA substrate. This is accomplished by two conserved backbone NH groups in active sites that form an oxyanion hole.


Pssm-ID: 119339 [Multi-domain]  Cd Length: 195  Bit Score: 143.47  E-value: 1.45e-42
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064  10 IEGAVARLTLNRPEVHNAFDDRLIEELTGALERFEQDQRLRLVILNATGTSFSAGADLNWMRRtAAYSWEENFADAQRLG 89
Cdd:cd06558   5 RDGGVATITLNRPEKRNALSLEMLDELAAALDEAEADPDVRVVVLTGAGKAFCAGADLKELAA-LSDAGEEARAFIRELQ 83
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064  90 RLMQMLDQLALPTLVQIHGAALGGGVGLVAACDIAVAADSAFFALAEVKLGLIP-AVISPYVIRAIGARAARRYFLTGER 168
Cdd:cd06558  84 ELLRALLRLPKPVIAAVNGAALGGGLELALACDIRIAAEDAKFGLPEVKLGLVPgGGGTQRLPRLVGPARARELLLTGRR 163
                       170       180       190
                ....*....|....*....|....*....|..
gi 88789064 169 ITAQQALRLGLVHEVVPDKQLDDRLAELAQTL 200
Cdd:cd06558 164 ISAEEALELGLVDEVVPDEELLAAALELARRL 195
menB TIGR01929
naphthoate synthase (dihydroxynaphthoic acid synthetase); This model represents an enzyme, ...
13-259 1.05e-23

naphthoate synthase (dihydroxynaphthoic acid synthetase); This model represents an enzyme, naphthoate synthase (dihydroxynaphthoic acid synthetase), which is involved in the fifth step of the menaquinone biosynthesis pathway. Together with o-succinylbenzoate-CoA ligase (menE: TIGR01923), this enzyme takes 2-succinylbenzoate and converts it into 1,4-di-hydroxy-2-naphthoate. Included above the trusted cutoff are two enzymes from Arabadopsis thaliana and one from Staphylococcus aureus which are identified as putative enoyl-CoA hydratase/isomerases. These enzymes group with the naphthoate synthases when building a tree and when doing BLAST searches. [Biosynthesis of cofactors, prosthetic groups, and carriers, Menaquinone and ubiquinone]


Pssm-ID: 200143 [Multi-domain]  Cd Length: 259  Bit Score: 96.08  E-value: 1.05e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064    13 AVARLTLNRPEVHNAFDDRLIEELTGALERFEQDQRLRLVILNATGT-SFSAGADLNwMRRTAAYSWEE-----NFADAQ 86
Cdd:TIGR01929  12 GIAKITINRPQVRNAFRPLTVKEIIQALDDAREDPDIGVVILTGAGDkAFCSGGDQK-VRGDYGYIDDSgvhrlNVLDVQ 90
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064    87 RLGRLMQMldqlalPTLVQIHGAALGGGVGLVAACDIAVAADSAFFALAEVKLGLIPAVI-SPYVIRAIGARAARRYFLT 165
Cdd:TIGR01929  91 RQIRTCPK------PVIAMVNGYAIGGGHVLHMMCDLTIAAENARFGQTGPKVGSFDGGYgSSYMARIVGQKKAREIWFL 164
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064   166 GERITAQQALRLGLVHEVVPDKQLDDRLAELAQTLLGNGPQAVRAAKRLIRTAGRDAIDASLIDETARRIAeqRASAEAK 245
Cdd:TIGR01929 165 CRQYDAKQALDMGLVNTVVPLADLEKETVRWCREILQKSPMAIRMLKAALNADCDGQAGLQELAGNATMLF--YMTEEGQ 242
                         250
                  ....*....|....
gi 88789064   246 EGVAAFLEKRKPDW 259
Cdd:TIGR01929 243 EGRNAFLEKRQPDF 256
 
Name Accession Description Interval E-value
PRK05995 PRK05995
enoyl-CoA hydratase; Provisional
1-260 3.76e-99

enoyl-CoA hydratase; Provisional


Pssm-ID: 235664 [Multi-domain]  Cd Length: 262  Bit Score: 290.29  E-value: 3.76e-99
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064    1 MQTKRLITMIEGAVARLTLNRPEVHNAFDDRLIEELTGALERFEQDQRLRLVILNATGTSFSAGADLNWMRRTAAYSWEE 80
Cdd:PRK05995   1 MMYETLEIEQRGQVATVTLNRPDVRNAFNETVIAELTAAFRALDADDSVRAVVLAGAGKAFCAGADLNWMKKMAGYSDDE 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064   81 NFADAQRLGRLMQMLDQLALPTLVQIHGAALGGGVGLVAACDIAVAADSAFFALAEVKLGLIPAVISPYVIRAIGARAAR 160
Cdd:PRK05995  81 NRADARRLADMLRAIYRCPKPVIARVHGDAYAGGMGLVAACDIAVAADHAVFCLSEVRLGLIPATISPYVIRAMGERAAR 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064  161 RYFLTGERITAQQALRLGLVHEVVPDKQLDDRLAELAQTLLGNGPQAVRAAKRLIRTAGRDAIDASLIDETARRIAEQRA 240
Cdd:PRK05995 161 RYFLTAERFDAAEALRLGLVHEVVPAEALDAKVDELLAALVANSPQAVRAGKRLVRDVAGRPIDAALIADTASRIALIRA 240
                        250       260
                 ....*....|....*....|
gi 88789064  241 SAEAKEGVAAFLEKRKPDWR 260
Cdd:PRK05995 241 TEEAREGVAAFLEKRKPAWR 260
PRK07468 PRK07468
crotonase/enoyl-CoA hydratase family protein;
14-260 1.99e-66

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 180987 [Multi-domain]  Cd Length: 262  Bit Score: 206.83  E-value: 1.99e-66
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064   14 VARLTLNRPEVHNAFDDRLIEELTGALERFEQDQRLRLVILNATGTSFSAGADLNWMRRTAAYSWEENFADAQRLGRLMQ 93
Cdd:PRK07468  15 VATLTLNRPEKHNALSARMIAELTTAARRLAADAAVRVVVLTGAGKSFCAGGDLGWMRAQMTADRATRIEEARRLAMMLK 94
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064   94 MLDQLALPTLVQIHGAALGGGVGLVAACDIAVAADSAFFALAEVKLGLIPAVISPYVIRAIGARAARRYFLTGERITAQQ 173
Cdd:PRK07468  95 ALNDLPKPLIGRIQGQAFGGGVGLISVCDVAIAVSGARFGLTETRLGLIPATISPYVVARMGEANARRVFMSARLFDAEE 174
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064  174 ALRLGLVHEVVPDKQLDDRLAELAQTLLGNGPQAVRAAKRLIRTAGrDAIDASLIDETARRIAEQRASAEAKEGVAAFLE 253
Cdd:PRK07468 175 AVRLGLLSRVVPAERLDAAVEAEVTPYLSCAPGAVAAAKALVRALG-APIDEAVIDATIEALADTWETEEAREGIAAFFD 253

                 ....*..
gi 88789064  254 KRKPDWR 260
Cdd:PRK07468 254 KRAPAWR 260
CaiD COG1024
Enoyl-CoA hydratase/carnithine racemase [Lipid transport and metabolism]; Enoyl-CoA hydratase ...
10-256 3.24e-64

Enoyl-CoA hydratase/carnithine racemase [Lipid transport and metabolism]; Enoyl-CoA hydratase/carnithine racemase is part of the Pathway/BioSystem: Fatty acid biosynthesis


Pssm-ID: 440647 [Multi-domain]  Cd Length: 249  Bit Score: 200.78  E-value: 3.24e-64
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064  10 IEGAVARLTLNRPEVHNAFDDRLIEELTGALERFEQDQRLRLVILNATGTSFSAGADLNWMRRTAAYswEENFADAQRLG 89
Cdd:COG1024   5 REGGVATITLNRPEKLNALSLEMLAELAAALDEAEADPDVRVVVLTGAGKAFCAGADLKELAAAADP--EEARAFARGLQ 82
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064  90 RLMQMLDQLALPTLVQIHGAALGGGVGLVAACDIAVAADSAFFALAEVKLGLIPAVISPYVIRAIG-ARAARRYFLTGER 168
Cdd:COG1024  83 RLFRALRRLPKPVIAAVNGAALGGGLELALACDLRIAAEDARFGLPEVRLGLIPGGGGTQRLPRLVgLARAKELLLTGRR 162
                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064 169 ITAQQALRLGLVHEVVPDKQLDDRLAELAQTLLGNGPQAVRAAKRLIRTAGRDAIDASLiDETARRIAEQRASAEAKEGV 248
Cdd:COG1024 163 IDAEEALELGLVNRVVPDDELLAAALALAARLAAGPPLALAATKRALNAALEAPLDEAL-ELEAEAFAELFASEDAREGI 241

                ....*...
gi 88789064 249 AAFLEKRK 256
Cdd:COG1024 242 AAFLEKRK 249
PRK05674 PRK05674
gamma-carboxygeranoyl-CoA hydratase; Validated
14-260 2.84e-62

gamma-carboxygeranoyl-CoA hydratase; Validated


Pssm-ID: 168168  Cd Length: 265  Bit Score: 196.57  E-value: 2.84e-62
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064   14 VARLTLNRPEVHNAFDDRLIEELTGALERFEQDQRLRLVILNATGTSFSAGADLNWMRRTAAYSWEENFADAQRLGRLMQ 93
Cdd:PRK05674  16 FATLWLSRADKNNAFNAQMIRELILALDQVQSDASLRFLLLRGRGRHFSAGADLAWMQQSADLDYNTNLDDARELAELMY 95
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064   94 MLDQLALPTLVQIHGAALGGGVGLVAACDIAVAADSAFFALAEVKLGLIPAVISPYVIRAIGARAARRYFLTGERITAQQ 173
Cdd:PRK05674  96 NLYRLKIPTLAVVQGAAFGGALGLISCCDMAIGADDAQFCLSEVRIGLAPAVISPFVVKAIGERAARRYALTAERFDGRR 175
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064  174 ALRLGLVHEVVPDKQLDDRLAELAQTLLGNGPQAVRAAKRLIRTAGRDAIDASLIDETARRIAEQRASAEAKEGVAAFLE 253
Cdd:PRK05674 176 ARELGLLAESYPAAELEAQVEAWIANLLLNSPQALRASKDLLREVGDGELSPALRRYCENAIARIRVSAEGQEGLRAFLE 255

                 ....*..
gi 88789064  254 KRKPDWR 260
Cdd:PRK05674 256 KRTPAWQ 262
ECH_1 pfam00378
Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: ...
10-260 2.16e-43

Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: enoyl-CoA hydratase, napthoate synthase, carnitate racemase, 3-hydroxybutyryl-CoA dehydratase and dodecanoyl-CoA delta-isomerase.


Pssm-ID: 395302 [Multi-domain]  Cd Length: 251  Bit Score: 147.51  E-value: 2.16e-43
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064    10 IEGAVARLTLNRPEVHNAFDDRLIEELTGALERFEQDQRLRLVILNATGTSFSAGADLNWM----RRTAAYSWEENFAda 85
Cdd:pfam00378   2 INAGVAVITLNRPEAVNALSAELITELIQALEKLRTDPSVRAVVLTGGDKAFCAGADLKEMygegPAHQALYRENVLD-- 79
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064    86 qrlgrLMQMLDQLALPTLVQIHGAALGGGVGLVAACDIAVAADSAFFALAEVKLGLIP-AVISPYVIRAIGARAARRYFL 164
Cdd:pfam00378  80 -----LWTLLYTCPKPVIAAVNGYAIGGGCELALACDIIIAADNASFGLNETKLGIIPgAGGTDRLPRIIGHSKAMEMLL 154
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064   165 TGERITAQQALRLGLVHEVVPDKQLDDRLAELAQTLLGNGPQAVRAAKRLIRTAGRDAidaslidETARRIAEQR----- 239
Cdd:pfam00378 155 LGRRISAQEALKWGLVDKVVPEDQLLDEARELAEKLAEKSPAALAQLKKALNAKLEDA-------LPTQLEAEARlfyst 227
                         250       260
                  ....*....|....*....|..
gi 88789064   240 -ASAEAKEGVAAFLEKRKPDWR 260
Cdd:pfam00378 228 fSKDDIIEGLQAFLEKRKPPWE 249
PRK08139 PRK08139
enoyl-CoA hydratase; Validated
10-260 5.07e-43

enoyl-CoA hydratase; Validated


Pssm-ID: 181249  Cd Length: 266  Bit Score: 147.01  E-value: 5.07e-43
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064   10 IEGAVARLTLNRPEVHNAFDDRLIEELTGALERFEQDQRLRLVILNATGTSFSAGADLNWMR--RTAAYsWEENFAdaqR 87
Cdd:PRK08139  17 DRDGVATLTLNRPQAFNALSEAMLAALQAALDAIAADPSVRVVVLAAAGKAFCAGHDLKEMRaaRGLAY-FRALFA---R 92
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064   88 LGRLMQMLDQLALPTLVQIHGAALGGGVGLVAACDIAVAADSAFFALAEVKLGLIPAVISPYVIRAIGARAARRYFLTGE 167
Cdd:PRK08139  93 CSRVMQAIVALPQPVIARVHGIATAAGCQLVASCDLAVAADTARFAVPGVNIGLFCSTPMVALSRNVPRKQAMEMLLTGE 172
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064  168 RITAQQALRLGLVHEVVPDKQLDDRLAELAQTLLGNGPQAVRAAKRLI-RTAGRDAIDAslIDETARRIAEQRASAEAKE 246
Cdd:PRK08139 173 FIDAATAREWGLVNRVVPADALDAAVARLAAVIAAKSPAAVRIGKEAFyRQAEMPLADA--YAYAGDVMAENMMAEDAEE 250
                        250
                 ....*....|....
gi 88789064  247 GVAAFLEKRKPDWR 260
Cdd:PRK08139 251 GIDAFLEKRPPEWR 264
crotonase-like cd06558
Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse ...
10-200 1.45e-42

Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase. Many of these play important roles in fatty acid metabolism. In addition to a conserved structural core and the formation of trimers (or dimers of trimers), a common feature in this superfamily is the stabilization of an enolate anion intermediate derived from an acyl-CoA substrate. This is accomplished by two conserved backbone NH groups in active sites that form an oxyanion hole.


Pssm-ID: 119339 [Multi-domain]  Cd Length: 195  Bit Score: 143.47  E-value: 1.45e-42
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064  10 IEGAVARLTLNRPEVHNAFDDRLIEELTGALERFEQDQRLRLVILNATGTSFSAGADLNWMRRtAAYSWEENFADAQRLG 89
Cdd:cd06558   5 RDGGVATITLNRPEKRNALSLEMLDELAAALDEAEADPDVRVVVLTGAGKAFCAGADLKELAA-LSDAGEEARAFIRELQ 83
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064  90 RLMQMLDQLALPTLVQIHGAALGGGVGLVAACDIAVAADSAFFALAEVKLGLIP-AVISPYVIRAIGARAARRYFLTGER 168
Cdd:cd06558  84 ELLRALLRLPKPVIAAVNGAALGGGLELALACDIRIAAEDAKFGLPEVKLGLVPgGGGTQRLPRLVGPARARELLLTGRR 163
                       170       180       190
                ....*....|....*....|....*....|..
gi 88789064 169 ITAQQALRLGLVHEVVPDKQLDDRLAELAQTL 200
Cdd:cd06558 164 ISAEEALELGLVDEVVPDEELLAAALELARRL 195
PRK07827 PRK07827
enoyl-CoA hydratase family protein;
10-259 2.64e-42

enoyl-CoA hydratase family protein;


Pssm-ID: 236109 [Multi-domain]  Cd Length: 260  Bit Score: 145.21  E-value: 2.64e-42
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064   10 IEGAVARLTLNRPEVHNAFDDRLIEELTGALERFEQDQRLRLVILNATGTSFSAGADLNWMRRTAAYSWEENFADAQRLG 89
Cdd:PRK07827  12 VDGGVATLTLDSPHNRNALSARLVAQLHDGLRAAAADPAVRAVVLTHTGGTFCAGADLSEAGGGGGDPYDAAVARAREMT 91
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064   90 RLMQMLDQLALPTLVQIHGAALGGGVGLVAACDIAVAADSAFFALAEVKLGLIPAVISPYVIRAIGARAARRYFLTGERI 169
Cdd:PRK07827  92 ALLRAIVELPKPVIAAIDGHVRAGGFGLVGACDIVVAGPESTFALTEARIGVAPAIISLTLLPRLSPRAAARYYLTGEKF 171
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064  170 TAQQALRLGLVHEVVPDkqLDDRLAELAQTLLGNGPQAVRAAKRLIRTAGRDAIDASLiDETARRIAEQRASAEAKEGVA 249
Cdd:PRK07827 172 GAAEAARIGLVTAAADD--VDAAVAALLADLRRGSPQGLAESKALTTAAVLAGFDRDA-EELTEESARLFVSDEAREGMT 248
                        250
                 ....*....|
gi 88789064  250 AFLEKRKPDW 259
Cdd:PRK07827 249 AFLQKRPPRW 258
PRK06688 PRK06688
enoyl-CoA hydratase; Provisional
1-260 5.86e-41

enoyl-CoA hydratase; Provisional


Pssm-ID: 235852 [Multi-domain]  Cd Length: 259  Bit Score: 141.54  E-value: 5.86e-41
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064    1 MQTKRLITMIEGAVARLTLNRPEVHNAFDDRLIEELTGALERFEQDQRLRLVILNATGTSFSAGADLNWMRRTAAYSWEE 80
Cdd:PRK06688   2 TMVTDLLVELEDGVLTITINRPDKKNALTAAMYQALADALEAAATDPAVRVVVLTGAGRAFSAGGDIKDFPKAPPKPPDE 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064   81 NfadaQRLGRLMQMLDQLALPTLVQIHGAALGGGVGLVAACDIAVAADSAFFALAEVKLGLIP-AVISPYVIRAIGARAA 159
Cdd:PRK06688  82 L----APVNRFLRAIAALPKPVVAAVNGPAVGVGVSLALACDLVYASESAKFSLPFAKLGLCPdAGGSALLPRLIGRARA 157
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064  160 RRYFLTGERITAQQALRLGLVHEVVPDKQLDDRLAELAQTLLGNGPQAVRAAKRLIRTAGRDAIDASLiDETARRIAEQR 239
Cdd:PRK06688 158 AEMLLLGEPLSAEEALRIGLVNRVVPAAELDAEADAQAAKLAAGPASALRYTKRAINAATLTELEEAL-AREAAGFGRLL 236
                        250       260
                 ....*....|....*....|.
gi 88789064  240 ASAEAKEGVAAFLEKRKPDWR 260
Cdd:PRK06688 237 RTPDFREGATAFIEKRKPDFT 257
PRK09245 PRK09245
crotonase/enoyl-CoA hydratase family protein;
6-257 1.22e-39

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181723  Cd Length: 266  Bit Score: 138.18  E-value: 1.22e-39
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064    6 LITMIEGAVARLTLNRPEVHNAF-DDRLIEELTGALERFEQDQRLRLVILNATGTSFSAGADLNWMR-RTAAYSWEenfA 83
Cdd:PRK09245   5 LLVERDGHIVTLTMNRPETRNALsDNDAVDALVAACAAINADRSVRAVILTGAGTAFSSGGNVKDMRaRVGAFGGS---P 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064   84 DAQRLG------RLMQMLDQLALPTLVQIHGAALGGGVGLVAACDIAVAADSAFFALAEVKLGLIP----AVISPYVIRA 153
Cdd:PRK09245  82 ADIRQGyrhgiqRIPLALYNLEVPVIAAVNGPAIGAGCDLACMCDIRIASETARFAESFVKLGLIPgdggAWLLPRIIGM 161
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064  154 IGARAARryfLTGERITAQQALRLGLVHEVVPDKQLDDRLAELAQTLLGNGPQAVRAAKRLIRtAGRDAIDASLIDETAR 233
Cdd:PRK09245 162 ARAAEMA---FTGDAIDAATALEWGLVSRVVPADQLLPAARALAERIAANPPHALRLTKRLLR-EGQHASLDTLLELSAA 237
                        250       260
                 ....*....|....*....|....
gi 88789064  234 RIAEQRASAEAKEGVAAFLEKRKP 257
Cdd:PRK09245 238 YQALAHHTADHREAVDAFLEKRPP 261
PRK06494 PRK06494
enoyl-CoA hydratase; Provisional
11-260 3.98e-39

enoyl-CoA hydratase; Provisional


Pssm-ID: 180591 [Multi-domain]  Cd Length: 259  Bit Score: 136.71  E-value: 3.98e-39
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064   11 EGAVARLTLNRPEVHNAFDDRLIEELTGALERFEQDQRLRLVILNATG-TSFSAGADLNWMRRTAAYSWEENfadaqRLG 89
Cdd:PRK06494  11 KGHVTIVTLNRPEVMNALHLDAHFELEEVFDDFAADPEQWVAIVTGAGdKAFSAGNDLKEQAAGGKRGWPES-----GFG 85
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064   90 RLMQMLDqLALPTLVQIHGAALGGGVGLVAACDIAVAADSAFFALAEVKLGLI---------PAVISPyviraigaRAAR 160
Cdd:PRK06494  86 GLTSRFD-LDKPIIAAVNGVAMGGGFELALACDLIVAAENATFALPEPRVGLAalagglhrlPRQIGL--------KRAM 156
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064  161 RYFLTGERITAQQALRLGLVHEVVPDKQLDDRLAELAQTLLGNGPQAVRAAKRLIrTAGRDAIDASLIDETARRIAEQ-- 238
Cdd:PRK06494 157 GMILTGRRVTAREGLELGFVNEVVPAGELLAAAERWADDILACSPLSIRASKQAV-YRGLEVSLEEAITAQRDYPAVEar 235
                        250       260
                 ....*....|....*....|..
gi 88789064  239 RASAEAKEGVAAFLEKRKPDWR 260
Cdd:PRK06494 236 RASQDYIEGPKAFAEKRPPRWK 257
PRK07658 PRK07658
enoyl-CoA hydratase; Provisional
10-257 1.41e-36

enoyl-CoA hydratase; Provisional


Pssm-ID: 181070 [Multi-domain]  Cd Length: 257  Bit Score: 130.14  E-value: 1.41e-36
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064   10 IEGAVARLTLNRPEVhNAFDDRLIEELTGALERFEQDQRLRLVILNATGTSFSAGADLnwmRRTAAYSWEENFADAQRLG 89
Cdd:PRK07658   8 VEDHVAVITLNHPPA-NALSSQVLHELSELLDQVEKDDNVRVVVIHGEGRFFSAGADI---KEFTSVTEAEQATELAQLG 83
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064   90 -RLMQMLDQLALPTLVQIHGAALGGGVGLVAACDIAVAADSAFFALAEVKLGLIPAV-----ISPYVIRAIGARAarryF 163
Cdd:PRK07658  84 qVTFERVEKFSKPVIAAIHGAALGGGLELAMSCHIRFATESAKLGLPELNLGLIPGFagtqrLPRYVGKAKALEM----M 159
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064  164 LTGERITAQQALRLGLVHEVVPDKQLDDRLAELAQTLLGNGPQAVRAAKRLIRTAGRDAIDASLIDEtARRIAEQRASAE 243
Cdd:PRK07658 160 LTSEPITGAEALKWGLVNGVFPEETLLDDAKKLAKKIAGKSPATTRAVLELLQTTKSSSYYEGVKRE-AKIFGEVFTSED 238
                        250
                 ....*....|....
gi 88789064  244 AKEGVAAFLEKRKP 257
Cdd:PRK07658 239 AKEGVQAFLEKRKP 252
PRK07799 PRK07799
crotonase/enoyl-CoA hydratase family protein;
11-260 2.09e-34

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181122 [Multi-domain]  Cd Length: 263  Bit Score: 124.44  E-value: 2.09e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064   11 EGAVARLTLNRPEVHNAFDDRLIEELTGALERFEQDQRLRLVILNATGTSFSAGADLNWMRRTAAyswEENFADA-QRLG 89
Cdd:PRK07799  12 RGHTLIVTMNRPEARNALSTEMLRIMVDAWDRVDNDPDIRSCILTGAGGAFCAGMDLKAATKKPP---GDSFKDGsYDPS 88
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064   90 RLMQMLD--QLALPTLVQIHGAALGGGVGLVAACDIAVAADSAFFALAEVKLGLIPAVIS--------PYVIRAIGaraa 159
Cdd:PRK07799  89 RIDALLKgrRLTKPLIAAVEGPAIAGGTEILQGTDIRVAGESAKFGISEAKWSLFPMGGSavrlvrqiPYTVACDL---- 164
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064  160 rryFLTGERITAQQALRLGLVHEVVPDKQLDDRLAELAQTLLGNGPQAVRAAKRLIR-TAGRDAIDASLIDetARRIAEQ 238
Cdd:PRK07799 165 ---LLTGRHITAAEAKEIGLIGHVVPDGQALDKALELAELINANGPLAVQAILRTIReTEGMHENEAFKID--TKIGIPV 239
                        250       260
                 ....*....|....*....|..
gi 88789064  239 RASAEAKEGVAAFLEKRKPDWR 260
Cdd:PRK07799 240 FLSEDAKEGPRAFAEKRAPNFQ 261
PRK07657 PRK07657
enoyl-CoA hydratase; Provisional
1-260 2.75e-33

enoyl-CoA hydratase; Provisional


Pssm-ID: 181069 [Multi-domain]  Cd Length: 260  Bit Score: 121.77  E-value: 2.75e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064    1 MQTKRLITMIEGAVARLTLNRPEVHNAFDDRLIEELTGALERFEQDQRLRLVILNATG-TSFSAGADLnwmRRTAAYSWE 79
Cdd:PRK07657   1 MLQNISVDYVTPHVVKITLNRPRAANALSLALLEELQNILTQINEEANVRVVILTGAGeKAFCAGADL---KERAGMNEE 77
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064   80 ENFADAQRLGRLMQMLDQLALPTLVQIHGAALGGGVGLVAACDIAVAADSAFFALAEVKLGLIP-AVISPYVIRAIGARA 158
Cdd:PRK07657  78 QVRHAVSLIRTTMEMVEQLPQPVIAAINGIALGGGLELALACDFRIAAESASLGLTETTLAIIPgAGGTQRLPRLIGVGR 157
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064  159 ARRYFLTGERITAQQALRLGLVHEVVPDKQLDDRLAELAQTLLGNGPQAVRAAKRLIrtagRDAIDASLidETARRIaEQ 238
Cdd:PRK07657 158 AKELIYTGRRISAQEAKEIGLVEFVVPAHLLEEKAIEIAEKIASNGPIAVRQAKEAI----SNGIQVDL--HTGLQI-EK 230
                        250       260
                 ....*....|....*....|....*...
gi 88789064  239 RA------SAEAKEGVAAFLEKRKPDWR 260
Cdd:PRK07657 231 QAyegtipTKDRLEGLQAFKEKRKPMYK 258
PRK06127 PRK06127
enoyl-CoA hydratase; Provisional
3-257 3.38e-32

enoyl-CoA hydratase; Provisional


Pssm-ID: 235705  Cd Length: 269  Bit Score: 119.04  E-value: 3.38e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064    3 TKRLITMIEGAVARLTLNRPEVHNAFDDRLIEELTGALERFEQDQRLRLVILN-ATGTSFSAGADLNWM--RRTAAyswE 79
Cdd:PRK06127  10 TGKLLAEKTGGLGRITFNNPARHNAMSLDMWEALPQALAAAEDDDAIRVVVLTgAGEKAFVSGADISQFeeSRSDA---E 86
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064   80 ENFADAQRLGRLMQMLDQLALPTLVQIHGAALGGGVGLVAACDIAVAADSAFFALAEVKLGL---------IPAVISPyv 150
Cdd:PRK06127  87 AVAAYEQAVEAAQAALADYAKPTIACIRGYCIGGGMGIALACDIRIAAEDSRFGIPAARLGLgygydgvknLVDLVGP-- 164
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064  151 iraigaRAARRYFLTGERITAQQALRLGLVHEVVPDKQLDDRLAELAQTLLGNGPQAVRAAKRLIRTAGRDAIDASlIDE 230
Cdd:PRK06127 165 ------SAAKDLFYTARRFDAAEALRIGLVHRVTAADDLETALADYAATIAGNAPLTLRAAKRAIAELLKDEPERD-MAA 237
                        250       260
                 ....*....|....*....|....*..
gi 88789064  231 TARRIAEQRASAEAKEGVAAFLEKRKP 257
Cdd:PRK06127 238 CQALVAACFDSEDYREGRAAFMEKRKP 264
PRK09674 PRK09674
enoyl-CoA hydratase-isomerase; Provisional
11-260 4.68e-32

enoyl-CoA hydratase-isomerase; Provisional


Pssm-ID: 182026 [Multi-domain]  Cd Length: 255  Bit Score: 118.33  E-value: 4.68e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064   11 EGAVARLTLNRPEVHNAFDDRLIEELTGALERFEQDQRLRLVILNATGTSFSAGADLNWMRrtaayswEENFADA--QRL 88
Cdd:PRK09674   9 QQRVLLLTLNRPEARNALNNALLTQLVNELEAAATDTSIGVCVITGNARFFAAGADLNEMA-------EKDLAATlnDPR 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064   89 GRLMQMLDQLALPTLVQIHGAALGGGVGLVAACDIAVAADSAFFALAEVKLGLIP-AVISPYVIRAIGARAARRYFLTGE 167
Cdd:PRK09674  82 PQLWQRLQAFNKPLIAAVNGYALGAGCELALLCDIVIAGENARFGLPEITLGIMPgAGGTQRLIRSVGKSLASQMVLTGE 161
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064  168 RITAQQALRLGLVHEVVPDKQLDDRLAELAQTLLGNGPQAVRAAKRLIRTAGRDAIDASLIDETARRIAeQRASAEAKEG 247
Cdd:PRK09674 162 SITAQQAQQAGLVSEVFPPELTLERALQLASKIARHSPLALRAAKQALRQSQEVDLQAGLAQERQLFTL-LAATEDRHEG 240
                        250
                 ....*....|...
gi 88789064  248 VAAFLEKRKPDWR 260
Cdd:PRK09674 241 ISAFLEKRTPDFK 253
PRK06563 PRK06563
crotonase/enoyl-CoA hydratase family protein;
11-260 1.18e-31

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 180625 [Multi-domain]  Cd Length: 255  Bit Score: 116.98  E-value: 1.18e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064   11 EGAVARLTLNRPEVHNAFDDRLIEELTGALERFEQDQRLRLVILNATGTSFSAGADL-NWMRRTAAYSWE--ENFADAQR 87
Cdd:PRK06563   6 RGHVLLIGLDRPAKRNAFDSAMLDDLALALGEYEADDELRVAVLFAHGEHFTAGLDLaDVAPKLAAGGFPfpEGGIDPWG 85
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064   88 LGRlmqmlDQLALPTLVQIHGAALGGGVGLVAACDIAVAADSAFFALAEVKLGLIP---AVISpyVIRAIGARAARRYFL 164
Cdd:PRK06563  86 TVG-----RRLSKPLVVAVQGYCLTLGIELMLAADIVVAADNTRFAQLEVQRGILPfggATLR--FPQAAGWGNAMRYLL 158
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064  165 TGERITAQQALRLGLVHEVVPDKQLDDRLAELAQTLLGNGPQAVRAAKRLIRTAGRDAIDASL--IDETARRIAeqrASA 242
Cdd:PRK06563 159 TGDEFDAQEALRLGLVQEVVPPGEQLERAIELAERIARAAPLGVQATLASARAAVREGEAAAAaqLPPELRPLF---TSE 235
                        250
                 ....*....|....*...
gi 88789064  243 EAKEGVAAFLEKRKPDWR 260
Cdd:PRK06563 236 DAKEGVQAFLERRPARFK 253
PRK08252 PRK08252
crotonase/enoyl-CoA hydratase family protein;
6-260 1.22e-31

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181325 [Multi-domain]  Cd Length: 254  Bit Score: 117.01  E-value: 1.22e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064    6 LITMIEGAVARLTLNRPEVHNAFDDRLIEELTGALERFEQDQRLRLVILNATGTSFSAGADLnwmrrtaaysweENFADA 85
Cdd:PRK08252   5 VLVERRGRVLIITINRPEARNAVNAAVAQGLAAALDELDADPDLSVGILTGAGGTFCAGMDL------------KAFARG 72
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064   86 QRL---GRLMQMLDQ--LALPTLVQIHGAALGGGVGLVAACDIAVAADSAFFALAEVKLGLIPA---VIS-----PYvir 152
Cdd:PRK08252  73 ERPsipGRGFGGLTErpPRKPLIAAVEGYALAGGFELALACDLIVAARDAKFGLPEVKRGLVAAgggLLRlprriPY--- 149
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064  153 aigaRAARRYFLTGERITAQQALRLGLVHEVVPDKQLDDRLAELAQTLLGNGPQAVRAAKRLIRTAGrDAIDASLIDETA 232
Cdd:PRK08252 150 ----HIAMELALTGDMLTAERAHELGLVNRLTEPGQALDAALELAERIAANGPLAVAASKRIVVESG-DWSEDEMFARQR 224
                        250       260
                 ....*....|....*....|....*...
gi 88789064  233 RRIAEQRASAEAKEGVAAFLEKRKPDWR 260
Cdd:PRK08252 225 ELIAPVFTSADAKEGATAFAEKRAPVWT 252
PRK09120 PRK09120
p-hydroxycinnamoyl CoA hydratase/lyase; Validated
9-257 1.26e-31

p-hydroxycinnamoyl CoA hydratase/lyase; Validated


Pssm-ID: 236383  Cd Length: 275  Bit Score: 117.42  E-value: 1.26e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064    9 MIEGAVARLTLNRPEVHNAFDDRLIEELTGALERFEQDQRLRLVILNATGTSFSAGADLNWMRRtaaysweENFADAQRL 88
Cdd:PRK09120  13 EVEDGIAWVTLNRPEKRNAMSPTLNREMIDVLDALEFDDDAGVLVLTGAGDAWSAGMDLKEYFR-------ETDAQPEIL 85
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064   89 GRLMQ--------MLDQLALPTLVQIHGAALGGGVGLVAACDIAVAADSAFFALAEVKLGLIPA-VISPYVIRAIGARAA 159
Cdd:PRK09120  86 QERIRreaygwwrRLRWYQKPTIAMVNGWCFGGGFSPLVACDLAIAADEAQFGLSEINWGIPPGgGVSKAMADTVGHRDA 165
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064  160 RRYFLTGERITAQQALRLGLVHEVVPDKQLDDRLAELAQTLLGNGPQAVRAAKRLIRTAGRDAIDASLIDETARRIAEQR 239
Cdd:PRK09120 166 LYYIMTGETFTGRKAAEMGLVNESVPLAQLRARTRELAAKLLEKNPVVLRAAKDGFKRVRELTWDQAEDYLYAKLEQANS 245
                        250       260
                 ....*....|....*....|..
gi 88789064  240 ASAEA--KEGVAAFLEKR--KP 257
Cdd:PRK09120 246 LDPEGgrEEGLKQFLDDKsyKP 267
PRK06143 PRK06143
enoyl-CoA hydratase; Provisional
11-256 5.81e-30

enoyl-CoA hydratase; Provisional


Pssm-ID: 180423  Cd Length: 256  Bit Score: 112.82  E-value: 5.81e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064   11 EGAVARLTLNRPEVHNAFDDRLIEELTGALERFEQDQRLRLVILNATGT-SFSAGADLNWMRRTAAYSWEenfADAQRLG 89
Cdd:PRK06143  14 DRGVATLTIRNAGSLNILGTPVILALTQALRWLAADPDVRVLVLRGAGEkAFIGGADIKEMATLDQASAE---AFISRLR 90
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064   90 RLMQMLDQLALPTLVQIHGAALGGGVGLVAACDIAVAADSAFFALAEVKLGlIPAVISPYVIRAIGARAARRYFL-TGER 168
Cdd:PRK06143  91 DLCDAVRHFPVPVIARIPGWCLGGGLELAAACDLRIAAHDAQFGMPEVRVG-IPSVIHAALLPRLIGWARTRWLLlTGET 169
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064  169 ITAQQALRLGLVHEVVPDKQLDDRLAELAQTLLGNGPQAVRAAKRLIRTAGRDAIDASlIDETARRIAEQRASAEAKEGV 248
Cdd:PRK06143 170 IDAAQALAWGLVDRVVPLAELDAAVERLAASLAGCGPQALRQQKRLLREWEDMPLDVA-IDDSVAEFGAAFLTGEPQRHM 248

                 ....*...
gi 88789064  249 AAFLEKRK 256
Cdd:PRK06143 249 AAFLNRKR 256
PRK05809 PRK05809
short-chain-enoyl-CoA hydratase;
1-260 6.87e-29

short-chain-enoyl-CoA hydratase;


Pssm-ID: 180270 [Multi-domain]  Cd Length: 260  Bit Score: 109.84  E-value: 6.87e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064    1 MQTKRLITMIEGAVARLTLNRPEVHNAFDDRLIEELTGALERFEQDQRLRLVILNATGT-SFSAGADLNWMRRTAAYSWE 79
Cdd:PRK05809   1 MELKNVILEKEGHIAVVTINRPKALNALNSETLKELDTVLDDIENDDNVYAVILTGAGEkAFVAGADISEMKDLNEEEGR 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064   80 ENFADAQRLGRLMQMLDQlalPTLVQIHGAALGGGVGLVAACDIAVAADSAFFALAEVKLGLIPAVI-SPYVIRAIGARA 158
Cdd:PRK05809  81 KFGLLGNKVFRKLENLDK---PVIAAINGFALGGGCELSMACDIRIASEKAKFGQPEVGLGITPGFGgTQRLARIVGPGK 157
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064  159 ARRYFLTGERITAQQALRLGLVHEVVPDKQLDDRLAELAQTLLGNGPQAVRAAKRLIRTAGRDAIDASLIDEtARRIAEQ 238
Cdd:PRK05809 158 AKELIYTGDMINAEEALRIGLVNKVVEPEKLMEEAKALANKIAANAPIAVKLCKDAINRGMQVDIDTAVAIE-AEDFGEC 236
                        250       260
                 ....*....|....*....|..
gi 88789064  239 RASAEAKEGVAAFLEKRKPDWR 260
Cdd:PRK05809 237 FSTEDQTEGMTAFVEKREKNFK 258
PRK09076 PRK09076
enoyl-CoA hydratase; Provisional
6-261 1.07e-28

enoyl-CoA hydratase; Provisional


Pssm-ID: 236373 [Multi-domain]  Cd Length: 258  Bit Score: 109.24  E-value: 1.07e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064    6 LITMIEGAVARLTLNRPEVhNAFDDRLIEELTGALERFEQDQRLR-LVILNATGTSFSAGADLNwmrrtaaysweeNFAD 84
Cdd:PRK09076   5 LDLEIDGHVAILTLNNPPA-NTWTADSLQALKQLVLELNADKDVYaLVITGDGEKFFSAGADLN------------LFAD 71
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064   85 ---------AQRLGRLMQMLDQLALPTLVQIHGAALGGGVGLVAACDIAVAADSAFFALAEVKLGLIPA----------- 144
Cdd:PRK09076  72 gdkavaremARRFGEAFEALSAFRGVSIAAINGYAMGGGLECALACDIRIAEEQAQMALPEASVGLLPCaggtqnlpwlv 151
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064  145 -------VIspyviraigaraarryfLTGERITAQQALRLGLVHEVVPDKQLDDRLAELAQTLLGNGPQAVRAAKRLIRT 217
Cdd:PRK09076 152 gegwakrMI-----------------LCGERVDAATALRIGLVEEVVEKGEAREAALALAQKVANQSPSAVAACKTLIQA 214
                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....
gi 88789064  218 AGRDAIDASLIDETArRIAEQRASAEAKEGVAAFLEKRKPDWRY 261
Cdd:PRK09076 215 ARNGPRAAALALERE-LFVDLFDTEDQREGVNAFLEKRAPQWKN 257
PRK07511 PRK07511
enoyl-CoA hydratase; Provisional
3-260 1.36e-28

enoyl-CoA hydratase; Provisional


Pssm-ID: 181009 [Multi-domain]  Cd Length: 260  Bit Score: 109.32  E-value: 1.36e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064    3 TKRLITMIEGAVARLTLNRPEVHNAFDDRLIEELTGALERFEQDQRLRLVILNATGTSFSAGADLNWMRRTAAYSWEENF 82
Cdd:PRK07511   2 SAELLSRREGSTLVLTLSNPGARNALHPDMYAAGIEALNTAERDPSIRAVVLTGAGGFFCAGGNLNRLLENRAKPPSVQA 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064   83 ADAQRLGRLMQMLDQLALPTLVQIHGAALGGGVGLVAACDIAVAADSAFFALAEVKLGLIP-AVISPYVIRAIGARAARR 161
Cdd:PRK07511  82 ASIDGLHDWIRAIRAFPKPVIAAVEGAAAGAGFSLALACDLLVAARDAKFVMAYVKVGLTPdGGGSWFLARALPRQLATE 161
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064  162 YFLTGERITAQQALRLGLVHEVV-PDKQLDDRLAeLAQTLLGNGPQAVRAAKRLIRTAGRDAIDASLIDEtARRIAEQRA 240
Cdd:PRK07511 162 LLLEGKPISAERLHALGVVNRLAePGQALAEALA-LADQLAAGSPNALARIKSLIADAPEATLAAQLEAE-RDHFVASLH 239
                        250       260
                 ....*....|....*....|
gi 88789064  241 SAEAKEGVAAFLEKRKPDWR 260
Cdd:PRK07511 240 HADALEGIAAFLEKRAPDYK 259
PRK08140 PRK08140
enoyl-CoA hydratase; Provisional
1-257 1.49e-28

enoyl-CoA hydratase; Provisional


Pssm-ID: 236163  Cd Length: 262  Bit Score: 109.23  E-value: 1.49e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064    1 MQTKRLITMIEGAVARLTLNRPEVHNAFDDRLIEELTGALERFEqDQRLRLVILNATGTSFSAGADLNWMRRTAA----- 75
Cdd:PRK08140   1 MMYETILLAIEAGVATLTLNRPDKLNSFTREMHRELREALDQVE-DDGARALLLTGAGRGFCAGQDLADRDVTPGgampd 79
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064   76 --YSWEENFADaqrlgrLMQMLDQLALPTLVQIHGAALGGGVGLVAACDIAVAADSAFFALAEVKLGLIP----AVISPY 149
Cdd:PRK08140  80 lgESIETFYNP------LVRRLRALPLPVIAAVNGVAAGAGANLALACDIVLAARSASFIQAFVKIGLVPdsggTWFLPR 153
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064  150 VIRAIGARAARryfLTGERITAQQALRLGLVHEVVPDKQLDDRLAELAQTLLGNGPQAVRAAKRLIRTAGRDAIDASL-I 228
Cdd:PRK08140 154 LVGMARALGLA---LLGEKLSAEQAEQWGLIWRVVDDAALADEAQQLAAHLATQPTRGLALIKQAMNASATNTLDAQLdL 230
                        250       260
                 ....*....|....*....|....*....
gi 88789064  229 DETARRIAEQraSAEAKEGVAAFLEKRKP 257
Cdd:PRK08140 231 ERDLQREAGR--SADYAEGVSAFLEKRAP 257
PRK08138 PRK08138
enoyl-CoA hydratase; Provisional
6-260 3.16e-28

enoyl-CoA hydratase; Provisional


Pssm-ID: 236162 [Multi-domain]  Cd Length: 261  Bit Score: 108.22  E-value: 3.16e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064    6 LITMIEGAVARLTLNRPEVHNAFDDRLIEELTGALERFEQDQRLRLVILNATGTSFSAGADLNWMRRTAAYSWEenfadA 85
Cdd:PRK08138  10 LLERPADGVALLRLNRPEARNALNMEVRQQLAEHFTELSEDPDIRAIVLTGGEKVFAAGADIKEFATAGAIEMY-----L 84
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064   86 QRLGRLMQMLDQLALPTLVQIHGAALGGGVGLVAACDIAVAADSAFFALAEVKLGLIP-AVISPYVIRAIGARAARRYFL 164
Cdd:PRK08138  85 RHTERYWEAIAQCPKPVIAAVNGYALGGGCELAMHADIIVAGESASFGQPEIKVGLMPgAGGTQRLVRAVGKFKAMRMAL 164
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064  165 TGERITAQQALRLGLVHEVVPDKQLDDRLAELAQTLLGNGPQAVRAAKRLIrTAGRDA-IDASLIDEtarRIAEQR--AS 241
Cdd:PRK08138 165 TGCMVPAPEALAIGLVSEVVEDEQTLPRALELAREIARMPPLALAQIKEVV-LAGADApLDAALALE---RKAFQLlfDS 240
                        250
                 ....*....|....*....
gi 88789064  242 AEAKEGVAAFLEKRKPDWR 260
Cdd:PRK08138 241 EDQKEGMDAFLEKRKPAYK 259
PRK11423 PRK11423
methylmalonyl-CoA decarboxylase; Provisional
7-260 3.76e-27

methylmalonyl-CoA decarboxylase; Provisional


Pssm-ID: 236908 [Multi-domain]  Cd Length: 261  Bit Score: 105.49  E-value: 3.76e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064    7 ITMIEGAVARLTLNRPEVHNAFDDRLIEELTGALERFEQdQRLRLVILNATGTS--FSAGADLNWM----RRTAAYSwee 80
Cdd:PRK11423   7 NVVTINKIATITFNNPAKRNALSKVLIDDLMQALSDLNR-PEIRVVILRAPSGSkvWSAGHDIHELpsggRDPLSYD--- 82
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064   81 nfadaQRLGRLMQMLDQLALPTLVQIHGAALGGGVGLVAACDIAVAADSAFFALAEVKLGLipavisPY-------VIRA 153
Cdd:PRK11423  83 -----DPLRQILRMIQKFPKPVIAMVEGSVWGGAFELIMSCDLIIAASTSTFAMTPANLGV------PYnlsgilnFTND 151
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064  154 IGARAARRYFLTGERITAQQALRLGLVHEVVPDKQLDDRLAELAQTLLGNGPQAVRAAKRLIRTAGrdaiDA-SLIDETA 232
Cdd:PRK11423 152 AGFHIVKEMFFTASPITAQRALAVGILNHVVEVEELEDFTLQMAHHISEKAPLAIAVIKEQLRVLG----EAhPMNPDEF 227
                        250       260       270
                 ....*....|....*....|....*....|..
gi 88789064  233 RRIAEQRA----SAEAKEGVAAFLEKRKPDWR 260
Cdd:PRK11423 228 ERIQGLRRavydSEDYQEGMNAFLEKRKPVFV 259
PRK06144 PRK06144
enoyl-CoA hydratase; Provisional
1-260 4.75e-27

enoyl-CoA hydratase; Provisional


Pssm-ID: 180424 [Multi-domain]  Cd Length: 262  Bit Score: 105.07  E-value: 4.75e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064    1 MQTKRLITMIEGAVARLTLNRPEVHNAFDDRLIEELTGALERFEQDQRLRLVILN-ATGTSFSAGADLNWMRrtAAYSWE 79
Cdd:PRK06144   5 TSTDELLLEVRGGIARITFNRPAARNAMTWAMYEGLAEICEAIAADPSIRAVVLRgAGDKAFVAGTDIAQFR--AFSTAE 82
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064   80 ENFADAQRLGRLMQMLDQLALPTLVQIHGAALGGGVGLVAACDIAVAADSAFFA----------LAEVKLGLIPAVISPy 149
Cdd:PRK06144  83 DAVAYERRIDRVLGALEQLRVPTIAAIAGACVGGGAAIAAACDLRIATPSARFGfpiartlgncLSMSNLARLVALLGA- 161
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064  150 viraigaRAARRYFLTGERITAQQALRLGLVHEVVPDKQLDDRLAELAQTLLGNGPQAVRAAK----RLIRTAGRDAIDa 225
Cdd:PRK06144 162 -------ARVKDMLFTARLLEAEEALAAGLVNEVVEDAALDARADALAELLAAHAPLTLRATKealrRLRREGLPDGDD- 233
                        250       260       270
                 ....*....|....*....|....*....|....*
gi 88789064  226 sLIDETarriaeqRASAEAKEGVAAFLEKRKPDWR 260
Cdd:PRK06144 234 -LIRMC-------YMSEDFREGVEAFLEKRPPKWK 260
PRK03580 PRK03580
crotonobetainyl-CoA hydratase;
11-260 6.93e-27

crotonobetainyl-CoA hydratase;


Pssm-ID: 179599 [Multi-domain]  Cd Length: 261  Bit Score: 104.78  E-value: 6.93e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064   11 EGAVARLTLNRPEVhNAFDDRLIEELTGALERFEQDQRLRLVILNATGTS-FSAGADLNwmrrtAAYSWEENFADAQRLG 89
Cdd:PRK03580  10 NGSILEITLDRPKA-NAIDAKTSFAMGEVFLNFRDDPELRVAIITGAGEKfFSAGWDLK-----AAAEGEAPDADFGPGG 83
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064   90 RL-MQMLDQLALPTLVQIHGAALGGGVGLVAACDIAVAADSAFFALAEVKLGLI---------PAVISPYVIRAIgaraa 159
Cdd:PRK03580  84 FAgLTEIFDLDKPVIAAVNGYAFGGGFELALAADFIVCADNASFALPEAKLGIVpdsggvlrlPKRLPPAIANEM----- 158
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064  160 rryFLTGERITAQQALRLGLVHEVVPDKQLDDRLAELAQTLLGNGPQAVRAAKRLIRTAGRDAIDASLIDETARRIAEQR 239
Cdd:PRK03580 159 ---VMTGRRMDAEEALRWGIVNRVVPQAELMDRARELAQQLVNSAPLAIAALKEIYRETSEMPVEEAYRYIRSGVLKHYP 235
                        250       260
                 ....*....|....*....|....
gi 88789064  240 A---SAEAKEGVAAFLEKRKPDWR 260
Cdd:PRK03580 236 SvlhSEDALEGPRAFAEKRDPVWK 259
PRK08290 PRK08290
enoyl-CoA hydratase; Provisional
10-213 4.05e-26

enoyl-CoA hydratase; Provisional


Pssm-ID: 236220 [Multi-domain]  Cd Length: 288  Bit Score: 103.12  E-value: 4.05e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064   10 IEGAVARLTLNRPEVHNAFDDRLIEELTGALERFEQDQRLRLVILNATGTSFSAGADLN------------WMRRTAAYS 77
Cdd:PRK08290  10 VAGRIARITLNRPEARNAQNRQMLYELDAAFRRAEADDAVRVIVLAGAGKHFSAGHDLGsgtpgrdrdpgpDQHPTLWWD 89
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064   78 WEENFADAQRLGRLMQMLDQLAL-------PTLVQIHGAALGGGVGLVAACDIAVAADSAFFALAEVKLGlIPAV---IS 147
Cdd:PRK08290  90 GATKPGVEQRYAREWEVYLGMCRrwrdlpkPTIAQVQGACIAGGLMLAWVCDLIVASDDAFFSDPVVRMG-IPGVeyfAH 168
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 88789064  148 PYVIRAIGARAarrYFLTGERITAQQALRLGLVHEVVPDKQLDDRLAELAQTLLGNGPQAVRAAKR 213
Cdd:PRK08290 169 PWELGPRKAKE---LLFTGDRLTADEAHRLGMVNRVVPRDELEAETLELARRIAAMPPFGLRLTKR 231
PRK05980 PRK05980
crotonase/enoyl-CoA hydratase family protein;
10-257 7.16e-26

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 180335 [Multi-domain]  Cd Length: 260  Bit Score: 102.14  E-value: 7.16e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064   10 IEGAVARLTLNRPEVHNAFDDRLIEELTGALERFEQDQRLRLVILNATGT-SFSAGADLNWMRRTAAYSWEENFADAQRL 88
Cdd:PRK05980   9 IRDGIALLTLNRPEKLNALNYALIDRLLARLDAIEVDESVRAVILTGAGDrAFSAGADIHEFSASVAAGADVALRDFVRR 88
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064   89 GRLM-QMLDQLALPTLVQIHGAALGGGVGLVAACDIAVAADSAFFALAEVKLGLIPAVI-SPYVIRAIGARAARRYFLTG 166
Cdd:PRK05980  89 GQAMtARLEAFPKPVIAAVNGLAFGGGCEITEAVHLAIASERALFAKPEIRLGMPPTFGgTQRLPRLAGRKRALELLLTG 168
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064  167 ERITAQQALRLGLVHEVVPDKQLDDRLAELAQTLLGNGPQAVRAAKRLIRTAGRDAIDASLIDETArRIAEQRASAEAKE 246
Cdd:PRK05980 169 DAFSAERALEIGLVNAVVPHEELLPAARALARRIIRHSPVAVAAILTAVTRGLNLSIAEGLLIESE-QFARMAGSADLRE 247
                        250
                 ....*....|.
gi 88789064  247 GVAAFLEKRKP 257
Cdd:PRK05980 248 GLAAWIERRRP 258
PRK05862 PRK05862
enoyl-CoA hydratase; Provisional
1-261 1.77e-25

enoyl-CoA hydratase; Provisional


Pssm-ID: 180295 [Multi-domain]  Cd Length: 257  Bit Score: 100.89  E-value: 1.77e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064    1 MQTKRLITMIEGAVARLTLNRPEVHNAFDDRLIEELTGALERFEQDQRLRLVILNATGTSFSAGADLNWMrrtAAYSW-- 78
Cdd:PRK05862   1 MAYETILVETRGRVGLITLNRPKALNALNDALMDELGAALAAFDADEGIGAIVITGSEKAFAAGADIKEM---ADLSFmd 77
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064   79 ---EENFADAQRLGRLMQmldqlalPTLVQIHGAALGGGVGLVAACDIAVAADSAFFALAEVKLGLIP-AVISPYVIRAI 154
Cdd:PRK05862  78 vykGDYITNWEKVARIRK-------PVIAAVAGYALGGGCELAMMCDIIIAADTAKFGQPEIKLGVLPgMGGSQRLTRAV 150
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064  155 GARAARRYFLTGERITAQQALRLGLVHEVVP-DKQLDDRLAeLAQTLLGNGPQAVRAAKRLIRTAGRDAIDASLIDEtaR 233
Cdd:PRK05862 151 GKAKAMDLCLTGRMMDAAEAERAGLVSRVVPaDKLLDEALA-AATTIASFSLPAVMMAKEAVNRAYETTLAEGLLFE--R 227
                        250       260
                 ....*....|....*....|....*....
gi 88789064  234 RIAEQR-ASAEAKEGVAAFLEKRKPDWRY 261
Cdd:PRK05862 228 RLFHSLfATEDQKEGMAAFVEKRKPVFKH 256
PRK06495 PRK06495
enoyl-CoA hydratase/isomerase family protein;
6-257 3.13e-25

enoyl-CoA hydratase/isomerase family protein;


Pssm-ID: 168580 [Multi-domain]  Cd Length: 257  Bit Score: 100.15  E-value: 3.13e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064    6 LITMIEGAVARLTLNRPEVhNAFDDRLIEELTGALERFEQDQRLRLVILNATGTSFSAGADLNwmRRTAAYSWEENFADA 85
Cdd:PRK06495   6 LKLEVSDHVAVVTLDNPPV-NALSRELRDELIAVFDEISERPDVRVVVLTGAGKVFCAGADLK--GRPDVIKGPGDLRAH 82
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064   86 QRLGRLM-QMLDQLALPTLVQIHGAALGGGVGLVAACDIAVAADSAFFALAEVKLGLIPAVisPYVIRAIGARAARRYFL 164
Cdd:PRK06495  83 NRRTRECfHAIRECAKPVIAAVNGPALGAGLGLVASCDIIVASENAVFGLPEIDVGLAGGG--KHAMRLFGHSLTRRMML 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064  165 TGERITAQQALRLGLVHEVVPDKQLDDRLAELAQTLLGNGPQAVRAAKRLIRTagrdaIDASLIDETAR----RIAEQRA 240
Cdd:PRK06495 161 TGYRVPAAELYRRGVIEACLPPEELMPEAMEIAREIASKSPLATRLAKDALNT-----IENMSLRDGYRyeqdITAKLAK 235
                        250
                 ....*....|....*..
gi 88789064  241 SAEAKEGVAAFLEKRKP 257
Cdd:PRK06495 236 TEDAKEAQRAFLEKRPP 252
PRK07509 PRK07509
crotonase/enoyl-CoA hydratase family protein;
2-260 6.33e-24

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181008 [Multi-domain]  Cd Length: 262  Bit Score: 96.87  E-value: 6.33e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064    2 QTKRLITMIEGAVARLTLNRPEVHNAFDDRLIEELTGALERFEQDQRLRLVILNATGTSFSAGADlnwMRRTAAysween 81
Cdd:PRK07509   1 MMDRVSVTIEDGIADVRLNRPDKMNALDFAMFEELIATIKRLKKDRGIRAVILSGEGGAFCAGLD---VKSVAS------ 71
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064   82 fADAQRLGRLMQMLD--------------QLALPTLVQIHGAALGGGVGLVAACDIAVAADSAFFALAEVKLGLIP---- 143
Cdd:PRK07509  72 -SPGNAVKLLFKRLPgnanlaqrvslgwrRLPVPVIAALEGVCFGGGLQIALGADIRIAAPDTKLSIMEAKWGLVPdmag 150
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064  144 -----AVISPYVIRAIGaraarryfLTGERITAQQALRLGLVHEVVpdkqlDDRLA---ELAQTLLGNGPQAVRAAKRLI 215
Cdd:PRK07509 151 tvslrGLVRKDVARELT--------YTARVFSAEEALELGLVTHVS-----DDPLAaalALAREIAQRSPDAIAAAKRLI 217
                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*
gi 88789064  216 RTAGRDAIDASLIDETARRIAEQRaSAEAKEGVAAFLEKRKPDWR 260
Cdd:PRK07509 218 NRSWTASVRALLARESVEQIRLLL-GKNQKIAVKAQMKKRAPKFL 261
menB TIGR01929
naphthoate synthase (dihydroxynaphthoic acid synthetase); This model represents an enzyme, ...
13-259 1.05e-23

naphthoate synthase (dihydroxynaphthoic acid synthetase); This model represents an enzyme, naphthoate synthase (dihydroxynaphthoic acid synthetase), which is involved in the fifth step of the menaquinone biosynthesis pathway. Together with o-succinylbenzoate-CoA ligase (menE: TIGR01923), this enzyme takes 2-succinylbenzoate and converts it into 1,4-di-hydroxy-2-naphthoate. Included above the trusted cutoff are two enzymes from Arabadopsis thaliana and one from Staphylococcus aureus which are identified as putative enoyl-CoA hydratase/isomerases. These enzymes group with the naphthoate synthases when building a tree and when doing BLAST searches. [Biosynthesis of cofactors, prosthetic groups, and carriers, Menaquinone and ubiquinone]


Pssm-ID: 200143 [Multi-domain]  Cd Length: 259  Bit Score: 96.08  E-value: 1.05e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064    13 AVARLTLNRPEVHNAFDDRLIEELTGALERFEQDQRLRLVILNATGT-SFSAGADLNwMRRTAAYSWEE-----NFADAQ 86
Cdd:TIGR01929  12 GIAKITINRPQVRNAFRPLTVKEIIQALDDAREDPDIGVVILTGAGDkAFCSGGDQK-VRGDYGYIDDSgvhrlNVLDVQ 90
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064    87 RLGRLMQMldqlalPTLVQIHGAALGGGVGLVAACDIAVAADSAFFALAEVKLGLIPAVI-SPYVIRAIGARAARRYFLT 165
Cdd:TIGR01929  91 RQIRTCPK------PVIAMVNGYAIGGGHVLHMMCDLTIAAENARFGQTGPKVGSFDGGYgSSYMARIVGQKKAREIWFL 164
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064   166 GERITAQQALRLGLVHEVVPDKQLDDRLAELAQTLLGNGPQAVRAAKRLIRTAGRDAIDASLIDETARRIAeqRASAEAK 245
Cdd:TIGR01929 165 CRQYDAKQALDMGLVNTVVPLADLEKETVRWCREILQKSPMAIRMLKAALNADCDGQAGLQELAGNATMLF--YMTEEGQ 242
                         250
                  ....*....|....
gi 88789064   246 EGVAAFLEKRKPDW 259
Cdd:TIGR01929 243 EGRNAFLEKRQPDF 256
PRK06210 PRK06210
enoyl-CoA hydratase; Provisional
11-257 1.32e-23

enoyl-CoA hydratase; Provisional


Pssm-ID: 180472  Cd Length: 272  Bit Score: 96.31  E-value: 1.32e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064   11 EGAVARLTLNRPEVHNAFDDRLIEELTGALERFEQDQRLRLVILNATGTSFSAGADLNWMRRTAA-----YSWEENF--- 82
Cdd:PRK06210  13 DSGVAVITLNRPDRLNAWTPVMEAEVYAAMDRAEADPAVRVIVLTGAGRGFCAGADMGELQTIDPsdgrrDTDVRPFvgn 92
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064   83 --ADAQRLGRLMQMLDQlalPTLVQIHGAALGGGVGLVAACDIAVAADSAFFALAEVKLGLIPAV-ISPYVIRAIGARAA 159
Cdd:PRK06210  93 rrPDYQTRYHFLTALRK---PVIAAINGACAGIGLTHALMCDVRFAADGAKFTTAFARRGLIAEHgISWILPRLVGHANA 169
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064  160 RRYFLTGERITAQQALRLGLVHEVVPDKQLDDRLAELAQTLLGN-GPQAVRAAKR-LIRTAGRDAIDASliDETARRIAE 237
Cdd:PRK06210 170 LDLLLSARTFYAEEALRLGLVNRVVPPDELMERTLAYAEDLARNvSPASMAVIKRqLYEDAFQTLAEAT--ARANREMHE 247
                        250       260
                 ....*....|....*....|
gi 88789064  238 QRASAEAKEGVAAFLEKRKP 257
Cdd:PRK06210 248 SLQRPDFIEGVASFLEKRPP 267
PRK05981 PRK05981
enoyl-CoA hydratase/isomerase;
1-256 1.73e-23

enoyl-CoA hydratase/isomerase;


Pssm-ID: 235661  Cd Length: 266  Bit Score: 95.96  E-value: 1.73e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064    1 MQTKRLITMIEGAVARLTLNRPEVHNAFDDRLIEELTGALERFEQDQ-RLRLVILNATGTSFSAGADLNWM---RRTAAY 76
Cdd:PRK05981   1 MQFKKVTLDFDGGVAILTLDHPEVMNAVSIDMLGGLAEALDAIEDGKaEVRCLVLTGAGRGFCTGANLQGRgsgGRESDS 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064   77 SWEENFADAQRLGRLMQMLDQLALPTLVQIHGAALGGGVGLVAACDIAVAADSAFFALAEVKLGLIPAVISPYVIRAIG- 155
Cdd:PRK05981  81 GGDAGAALETAYHPFLRRLRNLPCPIVTAVNGPAAGVGMSFALMGDLILCARSAYFLQAFRRIGLVPDGGSTWLLPRLVg 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064  156 ARAARRYFLTGERITAQQALRLGLVHEVVPDKQLDDRLAELAQTlLGNGPQavrAAKRLIRTAGRDAIDASLIDE-TARR 234
Cdd:PRK05981 161 KARAMELSLLGEKLPAETALQWGLVNRVVDDAELMAEAMKLAHE-LANGPT---VALGLIRKLYWDSPENDFEEQlNLER 236
                        250       260
                 ....*....|....*....|....
gi 88789064  235 IAEQRA--SAEAKEGVAAFLEKRK 256
Cdd:PRK05981 237 EAQRIAgkTEDFKEGVGAFLQKRP 260
PRK06190 PRK06190
enoyl-CoA hydratase; Provisional
1-250 2.25e-23

enoyl-CoA hydratase; Provisional


Pssm-ID: 235733  Cd Length: 258  Bit Score: 95.43  E-value: 2.25e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064    1 MQTKRLITMIEGAVARLTLNRPEVHNAFDDRLIEELTGALERFEQDQRLRLVILNATGTSFSAGADLnwmrRTAAYSWEE 80
Cdd:PRK06190   1 MTEPILLVETHDRVRTLTLNRPEARNALSAALRRALFAALAEADADDDVDVVVLTGADPAFCAGLDL----KELGGDGSA 76
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064   81 NFADAQRLGrLMQMLDQLALPTLVQIHGAALGGGVGLVAACDIAVAADSAFFALAEVKLGLIPAV-ISPYVIRAIGARAA 159
Cdd:PRK06190  77 YGAQDALPN-PSPAWPAMRKPVIGAINGAAVTGGLELALACDILIASERARFADTHARVGILPGWgLSVRLPQKVGIGRA 155
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064  160 RRYFLTGERITAQQALRLGLVHEVVPDKQLDDRLAELAQTLLGNGPQAVRAAKRLIRtAGRDAIDASLIDETARRIAEQR 239
Cdd:PRK06190 156 RRMSLTGDFLDAADALRAGLVTEVVPHDELLPRARRLAASIAGNNPAAVRALKASYD-DGAAAQTGDALALEAEAARAHN 234
                        250
                 ....*....|.
gi 88789064  240 ASAEAkEGVAA 250
Cdd:PRK06190 235 RSVSP-DGIAA 244
PRK07659 PRK07659
enoyl-CoA hydratase; Provisional
11-257 4.67e-23

enoyl-CoA hydratase; Provisional


Pssm-ID: 236073 [Multi-domain]  Cd Length: 260  Bit Score: 94.33  E-value: 4.67e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064   11 EGAVARLTLNRPEVHNAFDDRLIEELTGALERFEQDQRLrLVILNATGTSFSAGADLNWMrrtAAYSWEENFAdaqrlgR 90
Cdd:PRK07659  13 EGRVATIMLNRPEALNALDEPMLKELLQALKEVAESSAH-IVVLRGNGRGFSAGGDIKMM---LSSNDESKFD------G 82
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064   91 LMQMLDQLALpTLVQ--------IHGAALGGGVGLVAACDIAVAADSAFFALAEVKLGLIPavispyviraigaRAARRY 162
Cdd:PRK07659  83 VMNTISEIVV-TLYTmpkltisaIHGPAAGLGLSIALTADYVIADISAKLAMNFIGIGLIP-------------DGGGHF 148
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064  163 FLT--------------GERITAQQALRLGLVHEVV---PDKQLDDRLAELAQTLLgngpQAVRAAKRLIRTAGRDAIDA 225
Cdd:PRK07659 149 FLQkrvgenkakqiiweGKKLSATEALDLGLIDEVIggdFQTAAKQKISEWLQKPL----KAMIETKQIYCELNRSQLEQ 224
                        250       260       270
                 ....*....|....*....|....*....|..
gi 88789064  226 SLIDETARRiAEQRASAEAKEGVAAFLEKRKP 257
Cdd:PRK07659 225 VLQLEKRAQ-YAMRQTADHKEGIRAFLEKRLP 255
MenB COG0447
1,4-Dihydroxy-2-naphthoyl-CoA synthase [Coenzyme transport and metabolism]; 1, ...
14-259 5.66e-23

1,4-Dihydroxy-2-naphthoyl-CoA synthase [Coenzyme transport and metabolism]; 1,4-Dihydroxy-2-naphthoyl-CoA synthase is part of the Pathway/BioSystem: Menaquinone biosynthesis


Pssm-ID: 440216  Cd Length: 281  Bit Score: 94.50  E-value: 5.66e-23
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064  14 VARLTLNRPEVHNAFDDRLIEELTGALERFEQDQRLRLVILNATGTS------FSAGADLNwMRRTAAYSWEE-----NF 82
Cdd:COG0447  28 IARIAINRPEVRNAFRPETVDELYDALDHAREDPDVGVVLLTGNGPSkdggwaFCSGGDQR-VRGRGGYVYEDgvgrlNI 106
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064  83 ADAQRLGRLMqmldqlalPTLV-------------QIHgaalgggvglvAACDIAVAADSAFFALAEVKLGLIPAVI-SP 148
Cdd:COG0447 107 LEVQRLIRFM--------PKPViamvagwaiggghVLH-----------VVCDLTIASENARFGQTGPDVGSFDAGYgSA 167
                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064 149 YVIRAIGARAARRYFLTGERITAQQALRLGLVHEVVPDKQLDDRLAELAQTLLGNGPQAVRAAKrlirtAGRDAIDASLI 228
Cdd:COG0447 168 YLARQVGQKKAREIWFLCRQYSAQEALEMGLVNKVVPHAELEEEAVEWAREILEKSPTAIRMLK-----AAFNADDDGLA 242
                       250       260       270
                ....*....|....*....|....*....|....*.
gi 88789064 229 DE-----TARRIAeqRASAEAKEGVAAFLEKRKPDW 259
Cdd:COG0447 243 GQqefagEATRLA--YMTDEAQEGRDAFLEKRKPDF 276
PLN02921 PLN02921
naphthoate synthase
13-260 2.21e-22

naphthoate synthase


Pssm-ID: 178509 [Multi-domain]  Cd Length: 327  Bit Score: 94.08  E-value: 2.21e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064   13 AVARLTLNRPEVHNAFDDRLIEELTGALERFEQDQRLRLVILNATGT-SFSAGADLNwMRRTAAYSWEENFADAQRLGRL 91
Cdd:PLN02921  76 GIAKITINRPERRNAFRPRTVKELQRAFNDARDDSSVGVIILTGKGTkAFCSGGDQA-VRGKDGYVGPDDAGRLNVLDLQ 154
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064   92 MQMlDQLALPTLVQIHGAALGGGVGLVAACDIAVAADSAFFALAEVKLGLIPA-----VISPYVIRAIGARAarrYFLTg 166
Cdd:PLN02921 155 IQI-RRLPKPVIAMVAGYAVGGGHILHMVCDLTIAADNAVFGQTGPKVGSFDAgygssIMARLVGQKKAREM---WFLA- 229
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064  167 ERITAQQALRLGLVHEVVPDKQLDDRLAELAQTLLGNGPQAVRAAKRLIRTAGRDAIDASLIDETARRIAEQraSAEAKE 246
Cdd:PLN02921 230 RFYTASEALKMGLVNTVVPLDELEGETVKWCREILRNSPTAIRVLKSALNAADDGHAGLQELGGNATLLFYG--SEEGNE 307
                        250
                 ....*....|....
gi 88789064  247 GVAAFLEKRKPDWR 260
Cdd:PLN02921 308 GRTAYLEGRAPDFS 321
PLN02600 PLN02600
enoyl-CoA hydratase
14-260 3.04e-22

enoyl-CoA hydratase


Pssm-ID: 178210 [Multi-domain]  Cd Length: 251  Bit Score: 92.17  E-value: 3.04e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064   14 VARLTLNRPEVHNAFDDRLIEELTGALERFEQDQRLRLVILNATGTS-FSAGADLNwMRRTAAYSWEENFADAQRlgRLM 92
Cdd:PLN02600   5 IVELRLDRPEAKNAIGKEMLRGLRSAFEKIQADASARVVMLRSSVPGvFCAGADLK-ERRKMSPSEVQKFVNSLR--STF 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064   93 QMLDQLALPTLVQIHGAALGGGVGLVAACDIAVAADSAFFALAEVKLGLIP-AVISPYVIRAIGARAARRYFLTGERITA 171
Cdd:PLN02600  82 SSLEALSIPTIAVVEGAALGGGLELALSCDLRICGEEAVFGLPETGLAIIPgAGGTQRLPRLVGRSRAKELIFTGRRIGA 161
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064  172 QQALRLGLVHEVVPDKQLDDRLAELAQTLLGNGPQAVRAAKRLI-RTAGRDAIDASLIDETArrIAEQRASAEAKEGVAA 250
Cdd:PLN02600 162 REAASMGLVNYCVPAGEAYEKALELAQEINQKGPLAIKMAKKAInEGSEVDMASGLEIEEEC--YEQVLKTKDRLEGLAA 239
                        250
                 ....*....|
gi 88789064  251 FLEKRKPDWR 260
Cdd:PLN02600 240 FAEKRKPVYT 249
PRK06072 PRK06072
enoyl-CoA hydratase; Provisional
12-260 2.55e-21

enoyl-CoA hydratase; Provisional


Pssm-ID: 168377 [Multi-domain]  Cd Length: 248  Bit Score: 89.45  E-value: 2.55e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064   12 GAVARLTLNRPEVHNAFDDRLIEELTGALERFEQDQRLRLVILNATGTSFSAGADLNWMRRTAAYSWEENFadaQRLGRL 91
Cdd:PRK06072   8 EGYAIVTMSRPDKLNALNLEMRNEFISKLKQINADPKIRVVIVTGEGRAFCVGADLSEFAPDFAIDLRETF---YPIIRE 84
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064   92 MQMLDQLALPTlvqIHGAALGGGVGLVAACDIAVAADSAFFALAEVKLGLIPAVISPYVIRAIGARAARRYFLTGERITA 171
Cdd:PRK06072  85 IRFSDKIYISA---INGVTAGACIGIALSTDFKFASRDVKFVTAFQRLGLASDTGVAYFLLKLTGQRFYEILVLGGEFTA 161
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064  172 QQALRLGLVHevVPDKQLDDRLaELAQTLLgNGP-QAVRAAKRLIRTAGRDAIDASLIDETARRiAEQRASAEAKEGVAA 250
Cdd:PRK06072 162 EEAERWGLLK--ISEDPLSDAE-EMANRIS-NGPfQSYIAAKRMINLVLYNDLEEFLEYESAIQ-GYLGKTEDFKEGISS 236
                        250
                 ....*....|
gi 88789064  251 FLEKRKPDWR 260
Cdd:PRK06072 237 FKEKREPKFK 246
PRK08260 PRK08260
enoyl-CoA hydratase; Provisional
10-257 3.33e-21

enoyl-CoA hydratase; Provisional


Pssm-ID: 236206 [Multi-domain]  Cd Length: 296  Bit Score: 90.07  E-value: 3.33e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064   10 IEGAVARLTLNRPEVHNAFDDRLIEELTGALERFEQDQRLRLVILNATGTSFSAGADLN--------WMRRTAAYSWEEN 81
Cdd:PRK08260  10 VADGIATITLNRPDKLNAFTVTMARELIEAFDAADADDAVRAVIVTGAGRAFCAGADLSaggntfdlDAPRTPVEADEED 89
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064   82 ----FADAQRL--GRLMQMLDQLALPTLVQIHGAALGGGVGLVAACDIAVAADSAFFALAEVKLGLIP-AVISPYVIRAI 154
Cdd:PRK08260  90 radpSDDGVRDggGRVTLRIFDSLKPVIAAVNGPAVGVGATMTLAMDIRLASTAARFGFVFGRRGIVPeAASSWFLPRLV 169
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064  155 GARAARRYFLTGERITAQQALRLGLVHEVVPDKQLDDRLAELAQTLLGN-GPQAVRAAKRLI-RTAGRD-AIDASLIDet 231
Cdd:PRK08260 170 GLQTALEWVYSGRVFDAQEALDGGLVRSVHPPDELLPAARALAREIADNtSPVSVALTRQMMwRMAGADhPMEAHRVD-- 247
                        250       260
                 ....*....|....*....|....*.
gi 88789064  232 ARRIAEQRASAEAKEGVAAFLEKRKP 257
Cdd:PRK08260 248 SRAIYSRGRSGDGKEGVSSFLEKRPA 273
PRK07327 PRK07327
enoyl-CoA hydratase/isomerase family protein;
14-258 8.62e-20

enoyl-CoA hydratase/isomerase family protein;


Pssm-ID: 235991  Cd Length: 268  Bit Score: 85.84  E-value: 8.62e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064   14 VARLTLNRPEVHNAFDDRLIEELTGALERFEQDQRLRLVILNATGTSFSAGADLNWMRRTAAysweenfaDAQRLGRLMQ 93
Cdd:PRK07327  22 VLEIVLNGPGALNAADARMHRELADIWRDVDRDPDVRVVLIRGEGKAFSAGGDLALVEEMAD--------DFEVRARVWR 93
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064   94 MLDQLAL-------PTLVQIHGAALGGGVGLVAACDIAVAADSAFFALAEVKLGLIP----AVISPYVIRAIGARAarrY 162
Cdd:PRK07327  94 EARDLVYnvincdkPIVSAIHGPAVGAGLVAALLADISIAAKDARIIDGHTRLGVAAgdhaAIVWPLLCGMAKAKY---Y 170
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064  163 FLTGERITAQQALRLGLVHEVVPDKQLDDRLAELAQTLLGNGPQAVRAAKRLI----RTAGrDAIDASLIDETArriaeQ 238
Cdd:PRK07327 171 LLLCEPVSGEEAERIGLVSLAVDDDELLPKALEVAERLAAGSQTAIRWTKYALnnwlRMAG-PTFDTSLALEFM-----G 244
                        250       260
                 ....*....|....*....|
gi 88789064  239 RASAEAKEGVAAFLEKRKPD 258
Cdd:PRK07327 245 FSGPDVREGLASLREKRAPD 264
PRK07260 PRK07260
enoyl-CoA hydratase; Provisional
4-256 1.68e-19

enoyl-CoA hydratase; Provisional


Pssm-ID: 180910 [Multi-domain]  Cd Length: 255  Bit Score: 84.79  E-value: 1.68e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064    4 KRLITMIEGAVARLTLNRPEVHNAFDDRLIEELTGALERFEQDQRLRLVILNATGTSFSAGADLNWMRRTAAyswEENFA 83
Cdd:PRK07260   2 EHIIYEVEDDLATLTLNRPEVSNGFNIPMCQEILEALRLAEEDPSVRFLLINANGKVFSVGGDLVEMKRAVD---EDDVQ 78
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064   84 DAQRLGRLMQ----MLDQLALPTLVQIHGAALGGGVGLVAACDIAVAADSAFFALAEVKLGLIPAVISPYVIRAIGARAA 159
Cdd:PRK07260  79 SLVKIAELVNeisfAIKQLPKPVIMCVDGAVAGAAANMAVAADFCIASTKTKFIQAFVGVGLAPDAGGLFLLTRAIGLNR 158
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064  160 RRYF-LTGERITAQQALRLGLVHEVVPDKQLDDRLAELAQTLLGNGPQAVRAAKRLIrtagrdaIDASLIDETARRIAE- 237
Cdd:PRK07260 159 ATHLaMTGEALTAEKALEYGFVYRVAESEKLEKTCEQLLKKLRRGSSNSYAAIKSLV-------WESFFKGWEDYAKLEl 231
                        250       260
                 ....*....|....*....|....
gi 88789064  238 --QRASA---EAKEGVAAFLEKRK 256
Cdd:PRK07260 232 alQESLAfkeDFKEGVRAFSERRR 255
PRK06142 PRK06142
crotonase/enoyl-CoA hydratase family protein;
10-260 1.31e-18

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 235714  Cd Length: 272  Bit Score: 82.71  E-value: 1.31e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064   10 IEGAVARLTLNRPEVHNAFDDRLIEELTGALERFEQDQRLRLVILNATGTSFSAGADLNWMRRTAAYSWEENFA----DA 85
Cdd:PRK06142  12 LADHVAQVTLNRPGKGNAMNPAFWSELPEIFRWLDADPEVRAVVLSGSGKHFSYGIDLPAMAGVFGQLGKDGLArprtDL 91
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064   86 QRLGRLMQ----MLDQLALPTLVQIHGAALGGGVGLVAACDIAVAADSAFFALAEVKLGLI---------PAVISPYVIR 152
Cdd:PRK06142  92 RREILRLQaainAVADCRKPVIAAVQGWCIGGGVDLISACDMRYASADAKFSVREVDLGMVadvgslqrlPRIIGDGHLR 171
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064  153 AIGaraarryfLTGERITAQQALRLGLVHEVVPDKQ-LDDRLAELAQTLLGNGPQAVRAAKRLIRTAGRDAIDASLidet 231
Cdd:PRK06142 172 ELA--------LTGRDIDAAEAEKIGLVNRVYDDADaLLAAAHATAREIAAKSPLAVRGTKEVLDYMRDHRVADGL---- 239
                        250       260       270
                 ....*....|....*....|....*....|...
gi 88789064  232 aRRIAEQRA----SAEAKEGVAAFLEKRKPDWR 260
Cdd:PRK06142 240 -RYVATWNAamlpSKDLTEAIAAHMEKRPPEFT 271
PRK08321 PRK08321
1,4-dihydroxy-2-naphthoyl-CoA synthase;
10-259 1.35e-18

1,4-dihydroxy-2-naphthoyl-CoA synthase;


Pssm-ID: 181386  Cd Length: 302  Bit Score: 83.15  E-value: 1.35e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064   10 IEGAVARLTLNRPEVHNAFDDRLIEELTGALERFEQDQRLRLVILNATGTS-------FSAGADLNwMRRTAAYSWEE-- 80
Cdd:PRK08321  31 VDQGTVRIAFDRPEVRNAFRPHTVDELYRALDHARMSPDVGCVLLTGNGPSpkdggwaFCSGGDQR-IRGRDGYQYAEgd 109
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064   81 --NFADAQRLGRL----MQMLDQlALPTLV-------------QIHGAalgggvglvaaCDIAVA-ADSAFFALAEVKLG 140
Cdd:PRK08321 110 eaDTVDPARAGRLhileVQRLIR-FMPKVViavvpgwaaggghSLHVV-----------CDLTLAsREHARFKQTDADVG 177
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064  141 LIPAVI-SPYVIRAIGARAARRYFLTGERITAQQALRLGLVHEVVPDKQLDDRLAELAQTLLGNGPQAVRAAKrlirtAG 219
Cdd:PRK08321 178 SFDGGYgSAYLARQVGQKFAREIFFLGRTYSAEEAHDMGAVNAVVPHAELETEALEWAREINGKSPTAMRMLK-----YA 252
                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*
gi 88789064  220 RDAIDASLIDET-----ARRIAeqRASAEAKEGVAAFLEKRKPDW 259
Cdd:PRK08321 253 FNLTDDGLVGQQlfageATRLA--YMTDEAQEGRDAFLEKRDPDW 295
PRK08150 PRK08150
crotonase/enoyl-CoA hydratase family protein;
6-255 1.59e-18

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181254  Cd Length: 255  Bit Score: 81.99  E-value: 1.59e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064    6 LITMIEGAVARLTLNRPEVHNAFDDRLIEELTGALERFEQDqrLRLVILNATGTSFSAGADLNWMRRTAAY-------SW 78
Cdd:PRK08150   4 VSYELDGGVATIGLNRPAKRNALNDGLIAALRAAFARLPEG--VRAVVLHGEGDHFCAGLDLSELRERDAGegmhhsrRW 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064   79 EENFADAQRLGrlmqmldqlaLPTLVQIHGAALGGGVGLVAACDIAVAADSAFFALAEVKLGL---------IPAVISPY 149
Cdd:PRK08150  82 HRVFDKIQYGR----------VPVIAALHGAVVGGGLELASAAHIRVADESTYFALPEGQRGIfvggggsvrVPRLIGVA 151
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064  150 VIRAIgaraarryFLTGERITAQQALRLGLVHEVVPDKQLDDRLAELAQTLLGNGPQAVRA-AKRLIRTAGRDAIDASLI 228
Cdd:PRK08150 152 RMTDM--------MLTGRVYDAQEGERLGLAQYLVPAGEALDKAMELARRIAQNAPLTNFAvLNALPRIADMSADDGLFV 223
                        250       260
                 ....*....|....*....|....*..
gi 88789064  229 DETARRIAeqRASAEAKEGVAAFLEKR 255
Cdd:PRK08150 224 ESLMAAVA--QSAPEAKERLRAFLEKK 248
PRK07854 PRK07854
enoyl-CoA hydratase; Provisional
10-257 2.71e-18

enoyl-CoA hydratase; Provisional


Pssm-ID: 236115 [Multi-domain]  Cd Length: 243  Bit Score: 81.22  E-value: 2.71e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064   10 IEGAVARLTLNRPEVHNAFDDRLIEELTGALERFEqDQRLRLVILNATGTSFSAGADLnwmrrtAAYSWEENFADAqrLG 89
Cdd:PRK07854   6 RDGQVLTIELQRPERRNALNAELCEELREAVRKAV-DESARAIVLTGQGTVFCAGADL------SGDVYADDFPDA--LI 76
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064   90 RLMQMLDQLALPTLVQIHGAALGGGVGLVAACDIAVAADSAFFALAEVKLGLipaVISPYVIRAIGAR----AARRYFLT 165
Cdd:PRK07854  77 EMLHAIDAAPVPVIAAINGPAIGAGLQLAMACDLRVVAPEAYFQFPVAKYGI---ALDNWTIRRLSSLvgggRARAMLLG 153
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064  166 GERITAQQALRLGLVHEVVPdkqLDDRLAeLAQTLLGNGPQAVRAAKRLIRTAGrdAIDASLideTARRIAEQRA--SAE 243
Cdd:PRK07854 154 AEKLTAEQALATGMANRIGT---LADAQA-WAAEIAGLAPLALQHAKRVLNDDG--AIEEAW---PAHKELFDKAwaSQD 224
                        250
                 ....*....|....
gi 88789064  244 AKEGVAAFLEKRKP 257
Cdd:PRK07854 225 AIEAQVARIEKRPP 238
PLN02664 PLN02664
enoyl-CoA hydratase/delta3,5-delta2,4-dienoyl-CoA isomerase
13-257 7.93e-18

enoyl-CoA hydratase/delta3,5-delta2,4-dienoyl-CoA isomerase


Pssm-ID: 178269 [Multi-domain]  Cd Length: 275  Bit Score: 80.72  E-value: 7.93e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064   13 AVARLTLNRPEVHNAFDDRLIEELTGALERFEQDQRLRLVILNATGTSFSAGADLNWMRRTAAYSWEENFADA-QRLGRL 91
Cdd:PLN02664  17 SVFHLNLNRPSQRNALSLDFFTEFPKALSSLDQNPNVSVIILSGAGDHFCSGIDLKTLNSISEQSSSGDRGRSgERLRRK 96
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064   92 MQML-------DQLALPTLVQIHGAALGGGVGLVAACDIAVAADSAFFALAEVKLGL---------IPAVISpyviraig 155
Cdd:PLN02664  97 IKFLqdaitaiEQCRKPVIAAIHGACIGGGVDIVTACDIRYCSEDAFFSVKEVDLAItadlgtlqrLPSIVG-------- 168
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064  156 ARAARRYFLTGERITAQQALRLGLVHEVVPDKQ-LDDRLAELAQTLLGNGPQAVRAAKR-LIRtaGRDAIDASLIDETAR 233
Cdd:PLN02664 169 YGNAMELALTGRRFSGSEAKELGLVSRVFGSKEdLDEGVRLIAEGIAAKSPLAVTGTKAvLLR--SRELSVEQGLDYVAT 246
                        250       260
                 ....*....|....*....|....
gi 88789064  234 RIAEQRASAEAKEGVAAFLEKRKP 257
Cdd:PLN02664 247 WNSAMLVSDDLNEAVSAQIQKRKP 270
PRK05864 PRK05864
enoyl-CoA hydratase; Provisional
14-260 2.17e-17

enoyl-CoA hydratase; Provisional


Pssm-ID: 168278 [Multi-domain]  Cd Length: 276  Bit Score: 79.49  E-value: 2.17e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064   14 VARLTLNRPEVHNAFDDRLIEELTGALERFEQDQRLRLVILNATGTSFSAGADlnwMRRTAAYSWEENFADAQRLGRLMQ 93
Cdd:PRK05864  20 IALITLNRPERMNSMAFDVMVPLKEALAEVSYDNSVRVVVLTGAGRGFSSGAD---HKSAGVVPHVEGLTRPTYALRSME 96
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064   94 MLDQLAL-------PTLVQIHGAALGGGVGLVAACDIAVAADSAFFALAEVKLGLIPAV--ISPYVIRAIGARAARRYFL 164
Cdd:PRK05864  97 LLDDVILalrrlhqPVIAAVNGPAIGGGLCLALAADIRVASSSAYFRAAGINNGLTASElgLSYLLPRAIGSSRAFEIML 176
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064  165 TGERITAQQALRLGLVHEVVPDKQLDDRLAELAQTLLGNGPQAVRAAKRLIRTaGRDA--IDASLIDETARRIAEQRASA 242
Cdd:PRK05864 177 TGRDVDAEEAERIGLVSRQVPDEQLLDTCYAIAARMAGFSRPGIELTKRTLWS-GLDAasLEAHMQAEGLGQLFVRLLTA 255
                        250
                 ....*....|....*...
gi 88789064  243 EAKEGVAAFLEKRKPDWR 260
Cdd:PRK05864 256 NFEEAVAARAEKRPPVFT 273
PRK07396 PRK07396
dihydroxynaphthoic acid synthetase; Validated
14-260 2.82e-17

dihydroxynaphthoic acid synthetase; Validated


Pssm-ID: 180958 [Multi-domain]  Cd Length: 273  Bit Score: 79.17  E-value: 2.82e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064   14 VARLTLNRPEVHNAFDDRLIEELTGALERFEQDQRLRLVILNATG-TSFSAGADLNwMRRTAAYSWEE-----NFADAQR 87
Cdd:PRK07396  23 IAKITINRPEVRNAFRPKTVKEMIDAFADARDDDNIGVIILTGAGdKAFCSGGDQK-VRGYGGYVDDDgvprlNVLDLQR 101
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064   88 LGRLM-----QMLDQLALPTLVQIHgaalgggvglvAACDIAVAADSAFFALAEVKLGLIPAVI-SPYVIRAIGARAARR 161
Cdd:PRK07396 102 LIRTCpkpviAMVAGYAIGGGHVLH-----------LVCDLTIAADNAIFGQTGPKVGSFDGGYgASYLARIVGQKKARE 170
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064  162 YFLTGERITAQQALRLGLVHEVVPDKQLDDRLAELAQTLLGNGPQAVRAAKR-----------LIRTAGrdaiDASLIDE 230
Cdd:PRK07396 171 IWFLCRQYDAQEALDMGLVNTVVPLADLEKETVRWCREMLQNSPMALRCLKAalnadcdgqagLQELAG----NATMLFY 246
                        250       260       270
                 ....*....|....*....|....*....|
gi 88789064  231 TarriaeqraSAEAKEGVAAFLEKRKPDWR 260
Cdd:PRK07396 247 M---------TEEAQEGRNAFNEKRQPDFS 267
PRK07112 PRK07112
enoyl-CoA hydratase/isomerase;
10-189 5.92e-17

enoyl-CoA hydratase/isomerase;


Pssm-ID: 235938  Cd Length: 255  Bit Score: 77.80  E-value: 5.92e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064   10 IEGAVARLTLNRPEVHNAFDDRLIEELTGALERFEQDqrLRLVILNATGTSFSAGADLNWMRRTAAYSWEENFaDAQRLG 89
Cdd:PRK07112  10 QQGDVCFLQLHRPEAQNTINDRLIAECMDVLDRCEHA--ATIVVLEGLPEVFCFGADFSAIAEKPDAGRADLI-DAEPLY 86
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064   90 RLMQMLDQLALPTLVQIHGAALGGGVGLVAACDIAVAADSAFFALAEVKLGLIPAVISPYVIRAIGARAARRYFLTGERI 169
Cdd:PRK07112  87 DLWHRLATGPYVTIAHVRGKVNAGGIGFVAASDIVIADETAPFSLSELLFGLIPACVLPFLIRRIGTQKAHYMTLMTQPV 166
                        170       180
                 ....*....|....*....|
gi 88789064  170 TAQQALRLGLVHEVVPDKQL 189
Cdd:PRK07112 167 TAQQAFSWGLVDAYGANSDT 186
PLN02888 PLN02888
enoyl-CoA hydratase
6-215 6.19e-17

enoyl-CoA hydratase


Pssm-ID: 215480  Cd Length: 265  Bit Score: 77.87  E-value: 6.19e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064    6 LITMIEGAVARLTLNRPEVHNAFDDRLIEELTGALERFEQDQRLRLVILNATGTSFSAGADLnwmrrTAAyswEENF--- 82
Cdd:PLN02888  12 LVPKSRNGIATITINRPKALNALTRPMMVELAAAFKRLDEDDSVKVIILTGSGRAFCSGVDL-----TAA---EEVFkgd 83
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064   83 ADAQRLGRLMQMlDQLALPTLVQIHGAALGGGVGLVAACDIAVAADSAFFALAEVKLGLIPA---------VISPYVIRA 153
Cdd:PLN02888  84 VKDVETDPVAQM-ERCRKPIIGAINGFAITAGFEIALACDILVASRGAKFIDTHAKFGIFPSwglsqklsrIIGANRARE 162
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 88789064  154 IGaraarryfLTGERITAQQALRLGLVHEVVPDKQLDDRLAELAQTLLGNGPQAVRAAKRLI 215
Cdd:PLN02888 163 VS--------LTAMPLTAETAERWGLVNHVVEESELLKKAREVAEAIIKNNQGMVLRYKSVI 216
PRK05870 PRK05870
enoyl-CoA hydratase; Provisional
2-252 7.86e-17

enoyl-CoA hydratase; Provisional


Pssm-ID: 180298  Cd Length: 249  Bit Score: 77.46  E-value: 7.86e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064    2 QTKRLITMIEGAVARLTLNRPEVHNAFDDRLIEELTGALERFEQDQRLRLVILNATGTSFSAGADLNWMRRTAAYSWEen 81
Cdd:PRK05870   1 MMDPVLLDVDDGVALITVNDPDRRNAVTAEMSAQLRAAVAAAEADPDVHALVVTGAGKAFCAGADLTALGAAPGRPAE-- 78
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064   82 fadaQRLGRLMQ---MLDQLALPTLVQIHGAALGGGVGLVAACDIAVAADSAFFALAEVKLGLIPAVISPYVIRAIG-AR 157
Cdd:PRK05870  79 ----DGLRRIYDgflAVASCPLPTIAAVNGAAVGAGLNLALAADVRIAGPKALFDARFQKLGLHPGGGATWMLQRAVgPQ 154
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064  158 AARRYFLTGERITAQQALRLGLVHEVVPDKQldDRLAELAQTLLGNGPQAVRAAKRLIRTAGRDAIDASLIDetaRRIAE 237
Cdd:PRK05870 155 VARAALLFGMRFDAEAAVRHGLALMVADDPV--AAALELAAGPAAAPRELVLATKASMRATASLAQHAAAVE---FELGP 229
                        250
                 ....*....|....*
gi 88789064  238 QRASAEAKEgVAAFL 252
Cdd:PRK05870 230 QAASVQSPE-FAARL 243
PRK07938 PRK07938
enoyl-CoA hydratase family protein;
7-257 1.15e-16

enoyl-CoA hydratase family protein;


Pssm-ID: 181174  Cd Length: 249  Bit Score: 76.93  E-value: 1.15e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064    7 ITMIEGAVARLTLNRPEVhNAFDDRLIEELTGALERFEQDQRLRLVILNATGTSFSAGADLNWMRRTAAYsweENFADAQ 86
Cdd:PRK07938   5 STTPEPGIAEVTVDYPPV-NALPSAGWFALADAITAAGADPDTRVVVLRAEGRGFNAGVDIKELQATPGF---TALIDAN 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064   87 RlG--RLMQMLDQLALPTLVQIHGAALGGGVGLVAACDIAVAADSAFFALAEVKLGLIPAviSPYVIRAIGARAARRYFL 164
Cdd:PRK07938  81 R-GcfAAFRAVYECAVPVIAAVHGFCLGGGIGLVGNADVIVASDDATFGLPEVDRGALGA--ATHLQRLVPQHLMRALFF 157
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064  165 TGERITAQQALRLGLVHEVVPDKQLDDRLAELAQTLLGNGPQAVRAAKRLIRtaGRDAIDAslidETARRIaEQ------ 238
Cdd:PRK07938 158 TAATITAAELHHFGSVEEVVPRDQLDEAALEVARKIAAKDTRVIRAAKEALN--GIDPQDV----ERSYRW-EQgftfel 230
                        250
                 ....*....|....*....
gi 88789064  239 RASAEAKEGVAAFLEKRKP 257
Cdd:PRK07938 231 NLAGVSDEHRDAFVEKRKA 249
PRK06023 PRK06023
crotonase/enoyl-CoA hydratase family protein;
19-254 2.18e-16

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 168351  Cd Length: 251  Bit Score: 76.37  E-value: 2.18e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064   19 LNRPEVHNAFDDRLIEELTGALERFEQDQRLRLVILNATGTSFSAGADLNWMRRTAAYSWEENFADAQRLGRLMQM---- 94
Cdd:PRK06023  21 FNRPEKKNAITRAMYATMAKALKAADADDAIRAHVFLGTEGCFSAGNDMQDFLAAAMGGTSFGSEILDFLIALAEAekpi 100
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064   95 ---LDQLALPTLVQIHGAalgggvglvaaCDIAVAADSAFFALAEVKLGLIPAVISPYVIRAIGARAARRYFLT-GERIT 170
Cdd:PRK06023 101 vsgVDGLAIGIGTTIHLH-----------CDLTFASPRSLFRTPFVDLALVPEAGSSLLAPRLMGHQRAFALLAlGEGFS 169
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064  171 AQQALRLGLVHEVVPDKQLDDRLAELAQTLLGNGPQAVRAAKRLIRTAGRDAIDAslIDETARRIAEQRASAEAKEGVAA 250
Cdd:PRK06023 170 AEAAQEAGLIWKIVDEEAVEAETLKAAEELAAKPPQALQIARDLMRGPREDILAR--IDEEAKHFAARLKSAEARAAFEA 247

                 ....
gi 88789064  251 FLEK 254
Cdd:PRK06023 248 FMRR 251
PRK08272 PRK08272
crotonase/enoyl-CoA hydratase family protein;
12-218 3.72e-15

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 236213  Cd Length: 302  Bit Score: 73.54  E-value: 3.72e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064   12 GAVARLTLNRPEVHNAFDDRLIEELTGALERFEQDQRLRLVILNATGTSFSAGADL---------------NWMRRTAAY 76
Cdd:PRK08272  18 GRIARITLNRPEKGNAITADTPLELRAAVERADLDPGVHVILVSGAGKGFCAGYDLsayaegsssgggggaYPGKRQAVN 97
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064   77 S-----WEE--NFADAQRLGRLMQMLDQLALPTLVQIHGAALGGGVGLVAACDIAVAADSAffalaevKLGLIPAVI--S 147
Cdd:PRK08272  98 HlpddpWDPmiDYQMMSRFVRGFMSLWHAHKPTVAKVHGYCVAGGTDIALHCDQVIAADDA-------KIGYPPTRVwgV 170
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 88789064  148 PYVIR---AIGARAARRYFLTGERITAQQALRLGLVHEVVPDKQLDDRLAELAQTLLGNGPQAVRAAKRLIRTA 218
Cdd:PRK08272 171 PATGMwayRLGPQRAKRLLFTGDCITGAQAAEWGLAVEAVPPEELDERTERLVERIAAVPVNQLAMVKLAVNSA 244
PRK12478 PRK12478
crotonase/enoyl-CoA hydratase family protein;
1-215 1.30e-12

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 183548  Cd Length: 298  Bit Score: 66.13  E-value: 1.30e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064    1 MQTKRLITMIEGAVARLTLNRPEVHNAFDDRLIEELTGALERFEQDQRLRLVILNATGTSFSAGADL-----NW---MRR 72
Cdd:PRK12478   2 PDFQTLLYTTAGPVATITLNRPEQLNTIVPPMPDEIEAAIGLAERDQDIKVIVLRGAGRAFSGGYDFgggfqHWgeaMMT 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064   73 TAAYSWEENFA--DAQRLG---RLMQMLdQLALPTLVQIHGAALGGGVGLVAACDIAVAADSAFFALAEVKLGliPAVIS 147
Cdd:PRK12478  82 DGRWDPGKDFAmvTARETGptqKFMAIW-RASKPVIAQVHGWCVGGASDYALCADIVIASDDAVIGTPYSRMW--GAYLT 158
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 88789064  148 PYVIRAIGARAARRYFLTGERITAQQALRLGLVHEVVPDKQLDDRLAELAQTLLGNgPQAVRAAKRLI 215
Cdd:PRK12478 159 GMWLYRLSLAKVKWHSLTGRPLTGVQAAEAELINEAVPFERLEARVAEVATELARI-PLSQLQAQKLI 225
fadJ PRK11154
fatty acid oxidation complex subunit alpha FadJ;
7-197 1.53e-11

fatty acid oxidation complex subunit alpha FadJ;


Pssm-ID: 236864 [Multi-domain]  Cd Length: 708  Bit Score: 64.15  E-value: 1.53e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064    7 ITMIEGAVARLTLNRP-EVHNAFDDRLIEELTGALERFEQDQRLR-LVILNATGTSFSAGADLNWMR--RTAAysweenf 82
Cdd:PRK11154   9 LNVREDNIAVITIDVPgEKMNTLKAEFAEQVRAILKQLREDKELKgVVFISGKPDNFIAGADINMLAacKTAQ------- 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064   83 aDAQRLGR----LMQMLDQLALPTLVQIHGAALGGGVGLVAACDIAVAADSA--FFALAEVKLGLIPAV----------- 145
Cdd:PRK11154  82 -EAEALARqgqqLFAEIEALPIPVVAAIHGACLGGGLELALACHYRVCTDDPktVLGLPEVQLGLLPGSggtqrlprlig 160
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|..
gi 88789064  146 ISPyviraigaraARRYFLTGERITAQQALRLGLVHEVVPDKQLDDRLAELA 197
Cdd:PRK11154 161 VST----------ALDMILTGKQLRAKQALKLGLVDDVVPHSILLEVAVELA 202
ECH_2 pfam16113
Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: ...
14-254 2.60e-10

Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: enoyl-CoA hydratase, napthoate synthase, carnitate racemase, 3-hydroxybutyryl-CoA dehydratase and dodecanoyl-CoA delta-isomerase. This family differs from pfam00378 in the structure of it's C-terminus.


Pssm-ID: 465024 [Multi-domain]  Cd Length: 331  Bit Score: 59.79  E-value: 2.60e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064    14 VARLTLNRPEVHNAFDDRLIEELTGALERFEQDQRLRLVILNATGT-SFSAGADLNWMRRTA-AYSWEEN---FADaqrL 88
Cdd:pfam16113   1 VGVITLNRPKALNALNLEMVRALLAALKAWEDDPAVKLVVLKGAGErAFCAGGDVRALYEAAkAGGGEAGrdfFRE---E 77
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064    89 GRLMQMLDQLALPTL-------------VQIHgaalgggvglvaaCDIAVAADSAFFALAEVKLGLIPAV-ISpyvirai 154
Cdd:pfam16113  78 YRLNYLIATYPKPYValmdgivmgggvgLSVH-------------GSFRVVTERTRFAMPETAIGLFPDVgGS------- 137
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064   155 garaarrYFL-------------TGERITAQQALRLGLVHEVVPDKQLD---DRLAELAQTLLGNGPQAVRA-AKRLIRT 217
Cdd:pfam16113 138 -------YFLsrlpgelglylalTGARLNGADALAAGLATHYVPSARLPaleEALAALDWSDPADVDAVLAEfAEESDPP 210
                         250       260       270
                  ....*....|....*....|....*....|....*....
gi 88789064   218 AGRDAIDASLIDET--ARRIAEQRASAEAKEGVAAFLEK 254
Cdd:pfam16113 211 PSPLAAHREAIDRCfsADTVEEIIAALEAEADGDEWAAE 249
PLN02988 PLN02988
3-hydroxyisobutyryl-CoA hydrolase
11-256 5.28e-10

3-hydroxyisobutyryl-CoA hydrolase


Pssm-ID: 178568 [Multi-domain]  Cd Length: 381  Bit Score: 58.96  E-value: 5.28e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064   11 EGAVARLTLNRPEVHNAFDDRLIEELTGALERFEQDQRLRLVILNATGTSFSAGADLNWM-RRTAAYSWEEN---FADAQ 86
Cdd:PLN02988  16 KSSVRILTLNRPKQLNALSFHMISRLLQLFLAFEEDPSVKLVILKGHGRAFCAGGDVAAVvRDIEQGNWRLGanfFSDEY 95
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064   87 RLGRLMQMLDQLALPTLVQIhgaALGGGVGLVAACDIAVAADSAFFALAEVKLGLIPAVISPYVIRAIGARAARRYFLTG 166
Cdd:PLN02988  96 MLNYVMATYSKAQVSILNGI---VMGGGAGVSVHGRFRIATENTVFAMPETALGLFPDVGASYFLSRLPGFFGEYVGLTG 172
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064  167 ERITAQQALRLGLVHEVVPDKQLDDRLAEL----------AQTLLGNGPQAVR-----AAKRLirtagrDAIDASLIDET 231
Cdd:PLN02988 173 ARLDGAEMLACGLATHFVPSTRLTALEADLcrigsndptfASTILDAYTQHPRlkpqsAYHRL------DVIDRCFSRRT 246
                        250       260
                 ....*....|....*....|....*...
gi 88789064  232 ARRIA---EQRASAEAKEGVAAFLEKRK 256
Cdd:PLN02988 247 VEEIIsalEREATQEADGWISATIQALK 274
PLN02874 PLN02874
3-hydroxyisobutyryl-CoA hydrolase-like protein
12-201 9.94e-10

3-hydroxyisobutyryl-CoA hydrolase-like protein


Pssm-ID: 178462 [Multi-domain]  Cd Length: 379  Bit Score: 58.27  E-value: 9.94e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064   12 GAVARLTLNRPEVHNAFDDRLIEELTGALERFEQDQRLRLVILNATGTSFSAGADLN--WMRRTAAYSWEENfadAQRLG 89
Cdd:PLN02874  19 GRVRVITLNRPRQLNVISLSVVSLLAEFLEQWEKDDSVELIIIKGAGRAFSAGGDLKmfYDGRESDDSCLEV---VYRMY 95
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064   90 RLMQMLDQLALPTLVQIHGAALGGGVGLVAACDIAVAADSAFFALAEVKLGLIPAVISPYVIRAIGARAARRYFLTGERI 169
Cdd:PLN02874  96 WLCYHIHTYKKTQVALVHGLVMGGGAGLMVPMKFRVVTEKTVFATPEASVGFHTDCGFSYILSRLPGHLGEYLALTGARL 175
                        170       180       190
                 ....*....|....*....|....*....|..
gi 88789064  170 TAQQALRLGLVHEVVPDKqlddRLAELAQTLL 201
Cdd:PLN02874 176 NGKEMVACGLATHFVPSE----KLPELEKRLL 203
fadB PRK11730
fatty acid oxidation complex subunit alpha FadB;
7-212 3.81e-09

fatty acid oxidation complex subunit alpha FadB;


Pssm-ID: 183293 [Multi-domain]  Cd Length: 715  Bit Score: 56.79  E-value: 3.81e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064    7 ITMIEGAVARLTLNRPEVHNAFDDRLIEELTGALERFEQDQRLRLVILNATGTSFSAGADLNWMRRTAAYSWEENFADAQ 86
Cdd:PRK11730  10 VDWLEDGIAELVFDAPGSVNKLDRATLASLGEALDALEAQSDLKGLLLTSAKDAFIVGADITEFLSLFAAPEEELSQWLH 89
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064   87 RLGRLMQMLDQLALPTLVQIHGAALGGGVGLVAACDIAVAADSAFFALAEVKLGLIP----AVISPYViraIGARAARRY 162
Cdd:PRK11730  90 FANSIFNRLEDLPVPTVAAINGYALGGGCECVLATDYRVASPDARIGLPETKLGIMPgfggTVRLPRL---IGADNALEW 166
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|..
gi 88789064  163 FLTGERITAQQALRLGLVHEVV-PDKQLDDRLAELAQTLLGNGP-QAVRAAK 212
Cdd:PRK11730 167 IAAGKDVRAEDALKVGAVDAVVaPEKLQEAALALLKQAIAGKLDwKARRQPK 218
PRK05617 PRK05617
3-hydroxyisobutyryl-CoA hydrolase; Provisional
6-257 5.89e-08

3-hydroxyisobutyryl-CoA hydrolase; Provisional


Pssm-ID: 235533 [Multi-domain]  Cd Length: 342  Bit Score: 52.51  E-value: 5.89e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064    6 LITMIEGAVARLTLNRPEVHNAFDDRLIEELTGALERFEQDQRLRLVILNATGT-SFSAGADLNWMRRTA----AYSWEE 80
Cdd:PRK05617   5 VLAEVEGGVGVITLNRPKALNALSLEMIRAIDAALDAWEDDDAVAAVVIEGAGErGFCAGGDIRALYEAAragdPLAADR 84
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064   81 NFADAQRLGRL--------MQMLDQLALPTLVQI--HGaalgggvglvaacDIAVAADSAFFALAEVKLGLIPAVispyv 150
Cdd:PRK05617  85 FFREEYRLNALiarypkpyIALMDGIVMGGGVGIsaHG-------------SHRIVTERTKMAMPETGIGFFPDV----- 146
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064  151 iraigaraARRYFL-------------TGERITAQQALRLGLVHEVVPDKQLDDRLAELAQTLLGNGPQAVRAAKRLIRT 217
Cdd:PRK05617 147 --------GGTYFLsrapgalgtylalTGARISAADALYAGLADHFVPSADLPALLDALISLRWDSGADVVDAALAAFAT 218
                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|
gi 88789064  218 ---AGRDAIDASLIDET--ARRIAEQRASAEAKEG-----VAAFLEKRKP 257
Cdd:PRK05617 219 papASELAAQRAWIDECfaGDTVEDIIAALEADGGefaakTADTLRSRSP 268
PRK08259 PRK08259
crotonase/enoyl-CoA hydratase family protein;
11-251 8.97e-08

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 236205  Cd Length: 254  Bit Score: 51.82  E-value: 8.97e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064   11 EGAVARLTLNRPEVHNAFDDRLIEELTGALERFEQDQRLRLVILNATGTSFSAGADLnwmrrTAAYSWEENFADAQRLG- 89
Cdd:PRK08259  10 NGPVTTVILNRPEVRNAVDGPTAAALADAFRAFDADDAASVAVLWGAGGTFCAGADL-----KAVGTGRGNRLHPSGDGp 84
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064   90 ----RLMqmldqLALPTLVQIHGAALGGGVGLVAACDIAVAADSAFFALAEVKLG--LI-------PAVISpyviraigA 156
Cdd:PRK08259  85 mgpsRMR-----LSKPVIAAVSGYAVAGGLELALWCDLRVAEEDAVFGVFCRRWGvpLIdggtvrlPRLIG--------H 151
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064  157 RAARRYFLTGERITAQQALRLGLVHEVVPDKQLDDRLAELAQTLLGNgPQAVRAAKRL--IRTAGRDaIDASLIDETARR 234
Cdd:PRK08259 152 SRAMDLILTGRPVDADEALAIGLANRVVPKGQARAAAEELAAELAAF-PQTCLRADRLsaLEQWGLP-EEAALANEFAHG 229
                        250
                 ....*....|....*..
gi 88789064  235 IAeqRASAEAKEGVAAF 251
Cdd:PRK08259 230 LA--VLAAEALEGAARF 244
PRK08258 PRK08258
enoyl-CoA hydratase family protein;
10-259 1.47e-06

enoyl-CoA hydratase family protein;


Pssm-ID: 181329  Cd Length: 277  Bit Score: 48.42  E-value: 1.47e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064   10 IEGAVARLTLNRPEVHNAFDDRLIEELTGALERFEQDQRLRLVILNATGTSFSAGADLN-WMRRTAAYSWEENFADAQRL 88
Cdd:PRK08258  23 VDDGVATITLNRPERKNPLTFESYAELRDLFRELVYADDVKAVVLTGAGGNFCSGGDVHeIIGPLTKMDMPELLAFTRMT 102
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064   89 GRLMQMLDQLALPTLVQIHGAALGGGVGLVAACDIAVAADSAFFALAEVKLGL----------IPAVISpyviraigARA 158
Cdd:PRK08258 103 GDLVKAMRACPQPIIAAVDGVCAGAGAILAMASDLRLGTPSAKTAFLFTRVGLagadmgacalLPRIIG--------QGR 174
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064  159 ARRYFLTGERITAQQALRLGLVHEVVPDKQLDDRLAELAQTlLGNGP-QAVRAAKRLIRTAGRDAIDASLidetarriaE 237
Cdd:PRK08258 175 ASELLYTGRSMSAEEGERWGFFNRLVEPEELLAEAQALARR-LAAGPtFAHGMTKTMLHQEWDMGLEEAI---------E 244
                        250       260       270
                 ....*....|....*....|....*....|
gi 88789064  238 QRASAEA--------KEGVAAFLEKRKPDW 259
Cdd:PRK08258 245 AEAQAQAicmqtedfRRAYEAFVAKRKPVF 274
PRK07110 PRK07110
polyketide biosynthesis enoyl-CoA hydratase; Validated
10-65 2.73e-06

polyketide biosynthesis enoyl-CoA hydratase; Validated


Pssm-ID: 235936  Cd Length: 249  Bit Score: 47.27  E-value: 2.73e-06
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 88789064   10 IEGAVARLTLNRPEVHNAFDDRLIEELTGALERFEQDQRLRLVILNATGTSFSAGA 65
Cdd:PRK07110  11 VEEGIAQVTMQDRVNKNAFSDELCDQLHEAFDTIAQDPRYKVVILTGYPNYFATGG 66
fa_ox_alpha_mit TIGR02441
fatty acid oxidation complex, alpha subunit, mitochondrial; Members represent alpha subunit of ...
1-239 3.20e-06

fatty acid oxidation complex, alpha subunit, mitochondrial; Members represent alpha subunit of mitochondrial multifunctional fatty acid degradation enzyme complex. Subunit activities include: enoyl-CoA hydratase (EC 4.2.1.17) _ 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35). Some characterization in human (SP:P40939), pig (SP:Q29554), and rat (SP:Q64428). The beta subunit has activity: acetyl-CoA C-acyltransferase (EC 2.3.1.16).


Pssm-ID: 131494 [Multi-domain]  Cd Length: 737  Bit Score: 47.91  E-value: 3.20e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064     1 MQTKRLITMIEGAVARLTLNRPEVH-NAFDDRLIEELTGALERFEQDQRLR-LVILNATGTSFSAGADLNWMRrtAAYSW 78
Cdd:TIGR02441  10 MARTHRHYEVKGDVAVVKIDSPNSKvNTLSKELFAEFKEVMNELWTNEAIKsAVLISGKPGSFVAGADIQMIA--ACKTA 87
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064    79 EENFADAQRLGRLMQMLDQLALPTLVQIHGAALGGGVGLVAACD--IAVAADSAFFALAEVKLGLIP-AVISPYVIRAIG 155
Cdd:TIGR02441  88 QEVTQLSQEGQEMFERIEKSQKPIVAAISGSCLGGGLELALACHyrIATKDRKTLLGLPEVMLGLLPgAGGTQRLPKLTG 167
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064   156 ARAARRYFLTGERITAQQALRLGLVHEVV---------PDKQLDDRLAELAQTL---LGNGPQAVRAAKRLIRTAGRDAI 223
Cdd:TIGR02441 168 VPAALDMMLTGKKIRADRAKKMGIVDQLVdplgpglkpAEENTIEYLEEVAVKFaqgLANGKLSINRDKGLVHKITQYVM 247
                         250
                  ....*....|....*.
gi 88789064   224 DASLIDETARRIAEQR 239
Cdd:TIGR02441 248 TNPFVRQQVYKTAEDK 263
PLN03214 PLN03214
probable enoyl-CoA hydratase/isomerase; Provisional
12-218 8.69e-06

probable enoyl-CoA hydratase/isomerase; Provisional


Pssm-ID: 215635  Cd Length: 278  Bit Score: 46.03  E-value: 8.69e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064   12 GAVARLTLNRPEVhNAFDDRLIEELTGALERFEQDQRLRLVILnATGTS---FSAGADLNWMR--RTAAYSWEEnFADAQ 86
Cdd:PLN03214  20 GGIAVVWLAKEPV-NSMTLAMWRSLDDALTALENDPTVRGVVF-ASGLRrdvFTAGNDIAELYapKTSAARYAE-FWLTQ 96
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064   87 R--LGRLMQMldqlALPTLVQIHGAALGGGVGLVAACDIAVAADSAFFALAEVKLG----------LIPAVISPYVIRAI 154
Cdd:PLN03214  97 TtfLVRLLRS----RLATVCAIRGACPAGGCAVSLCCDYRLQTTEGTMGLNEVALGipvpkfwarlFMGRVIDRKVAESL 172
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 88789064  155 garaarryFLTGERITAQQALRLGLVHEVVPDKQLDDRLAELAQTLLGNGPQAVRAAKRLIRTA 218
Cdd:PLN03214 173 --------LLRGRLVRPAEAKQLGLIDEVVPAAALMEAAASAMERALKLPSAARAATKALLREE 228
PRK06213 PRK06213
crotonase/enoyl-CoA hydratase family protein;
10-232 2.19e-03

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 235744  Cd Length: 229  Bit Score: 38.42  E-value: 2.19e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064   10 IEGAVARLTLNRPEVhNAFDDRLIEELTGALERFEQDQRLrlVILNATGTSFSAGADLNWMRRTAAYSWE---ENFADAQ 86
Cdd:PRK06213   9 LEDGVATITLDDGKV-NALSPAMIDALNAALDQAEDDRAV--VVITGQPGIFSGGFDLKVMTSGAQAAIAlltAGSTLAR 85
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064   87 RLgrlmqmldqLALPTLVQI----HGAALGGGVGLVaaCDIAVAADSAF-FALAEVKLGL-IPAVISPYVIRAIGARAAR 160
Cdd:PRK06213  86 RL---------LSHPKPVIVactgHAIAKGAFLLLS--ADYRIGVHGPFkIGLNEVAIGMtMPHAAIELARDRLTPSAFQ 154
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 88789064  161 RYFLTGERITAQQALRLGLVHEVVPDKQLDDRLAELAQTLLGNGPQAVRAAKRLIRTAGRDAIDASLIDETA 232
Cdd:PRK06213 155 RAVINAEMFDPEEAVAAGFLDEVVPPEQLLARAQAAARELAGLNMGAHAATKLKVRAAALEAIRAAIEGDAA 226
PRK05869 PRK05869
enoyl-CoA hydratase; Validated
14-212 3.86e-03

enoyl-CoA hydratase; Validated


Pssm-ID: 235632 [Multi-domain]  Cd Length: 222  Bit Score: 37.51  E-value: 3.86e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064   14 VARLTLNRPEVhNAFDDRLIEELTGALERFEQDQRLRLVILNATGTSFSAGADLNWMRRTAAyswEENFADAQRLGRLMQ 93
Cdd:PRK05869  18 LATLLLSRPPT-NALTRQVYREIVAAANELGRRDDVAAVILYGGHEIFSAGDDMPELRTLSA---QEADTAARVRQQAVD 93
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064   94 MLDQLALPTLVQIHGAALGGGVGLVAACDIAVAADSAFFALAEVKLGLIPAV-ISPYVIRAIGARAARRYFLTGERITAQ 172
Cdd:PRK05869  94 AVAAIPKPTVAAITGYALGAGLTLALAADWRVSGDNVKFGATEILAGLAPSGdGMARLTRAAGPSRAKELVFSGRFFDAE 173
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|
gi 88789064  173 QALRLGLVHEVVPDKQLDDRLAELAQTLLGNGPQAVRAAK 212
Cdd:PRK05869 174 EALALGLIDEMVAPDDVYDAAAAWARRFLDGPPHALAAAK 213
PLN02157 PLN02157
3-hydroxyisobutyryl-CoA hydrolase-like protein
9-210 7.32e-03

3-hydroxyisobutyryl-CoA hydrolase-like protein


Pssm-ID: 177817 [Multi-domain]  Cd Length: 401  Bit Score: 37.36  E-value: 7.32e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064    9 MIEGAVARLT--LNRPEVHNAFDDRLIEELTGALERFEQDQRLRLVILNATGTSFSAGADL----NWMRRTAAYSWEENF 82
Cdd:PLN02157  40 LVEGSGCSRTaiLNRPPALNALTTHMGYRLQKLYKNWEEDPNIGFVMMKGSGRAFCAGGDIvslyHLRKRGSPDAIREFF 119
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88789064   83 ADaqrLGRLMQMLDQLALPTLVQIHGAALGGGVGLVAACDIAVAADSAFFALAEVKLGLIPAVISPYVIRAIGARAARRY 162
Cdd:PLN02157 120 SS---LYSFIYLLGTYLKPHVAILNGVTMGGGTGVSIPGTFRVATDRTIFATPETIIGFHPDAGASFNLSHLPGRLGEYL 196
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*...
gi 88789064  163 FLTGERITAQQALRLGLVHEVVPDKQLdDRLAELAQTLLGNGPQAVRA 210
Cdd:PLN02157 197 GLTGLKLSGAEMLACGLATHYIRSEEI-PVMEEQLKKLLTDDPSVVES 243
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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