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Conserved domains on  [gi|88784158|gb|EAR15328|]
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wlac protein [Robiginitalea biformata HTCC2501]

Protein Classification

glycosyltransferase family 4 protein( domain architecture ID 10133618)

glycosyltransferase family 4 (GT4) protein similar to Erwinia amylovora amylovoran biosynthesis glycosyltransferase AmsD, which may be involved in the formation of galactose alpha-1,6 linkages in amylovoran; glycosyltransferase 4 subfamily belongs to the large glycosyltransferase group 1 family

CAZY:  GT4
EC:  2.4.-.-
Gene Ontology:  GO:0016757
PubMed:  12691742|16037492
SCOP:  3001586

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
GT4_AmsD-like cd03820
amylovoran biosynthesis glycosyltransferase AmsD and similar proteins; This family is most ...
 2-289 3.83e-91

amylovoran biosynthesis glycosyltransferase AmsD and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. AmSD in Erwinia amylovora has been shown to be involved in the biosynthesis of amylovoran, the acidic exopolysaccharide acting as a virulence factor. This enzyme may be responsible for the formation of galactose alpha-1,6 linkages in amylovoran.


:

Pssm-ID: 340847 [Multi-domain]  Cd Length: 351  Bit Score: 274.50  E-value: 3.83e-91
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88784158   2 ESIRNNWRLYKRVNTLIRENRIELCIGFMTTSNVLsvLASRSNGIPVVISERNNPEEEKNKLshLWRFLKKYTYRKADKL 81
Cdd:cd03820  67 KLLLKYFKKVRRLRKYLKNNKPDVVISFRTSLLTF--LALIGLKSKLIVWEHNNYEAYNKGL--RRLLLRRLLYKRADKI 142

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88784158  82 VVQNNRIKSLYiNDIDNKKLQIIPNPINPGLRPDPNVEMSNIILNVGRLERQKAQDTLIKAFANL--NPSGWELHIIGDG 159
Cdd:cd03820 143 VVLTEADKLKK-YKQPNSNVVVIPNPLSFPSEEPSTNLKSKRILAVGRLTYQKGFDLLIEAWALIakKHPDWKLRIYGDG 221

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88784158 160 RQRSYLEALIDQLHMNDKVRLLGKKKNIQPYYAKARIFVLSSLYEGFPNVLLEAMQMGKACISTDCPTGPSDIISHGDDG 239
Cdd:cd03820 222 PEREELEKLIDKLGLEDRVKLLGPTKNIAEEYANSSIFVLSSRYEGFPMVLLEAMAYGLPIISFDCPTGPSEIIEDGENG 301

                       250       260       270       280       290
                ....*....|....*....|....*....|....*....|....*....|
gi 88784158 240 ILVPVGNTAELEAALRDLIENPAKERQLGEKAKDATRPYQIENIAAVWEE 289
Cdd:cd03820 302 LLVPNGDVDALAEALLRLMEDEELRKKMGKNARKNAERFSIEKIIKQWEE 351
 
Name Accession Description Interval E-value
GT4_AmsD-like cd03820
amylovoran biosynthesis glycosyltransferase AmsD and similar proteins; This family is most ...
 2-289 3.83e-91

amylovoran biosynthesis glycosyltransferase AmsD and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. AmSD in Erwinia amylovora has been shown to be involved in the biosynthesis of amylovoran, the acidic exopolysaccharide acting as a virulence factor. This enzyme may be responsible for the formation of galactose alpha-1,6 linkages in amylovoran.


Pssm-ID: 340847 [Multi-domain]  Cd Length: 351  Bit Score: 274.50  E-value: 3.83e-91
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88784158   2 ESIRNNWRLYKRVNTLIRENRIELCIGFMTTSNVLsvLASRSNGIPVVISERNNPEEEKNKLshLWRFLKKYTYRKADKL 81
Cdd:cd03820  67 KLLLKYFKKVRRLRKYLKNNKPDVVISFRTSLLTF--LALIGLKSKLIVWEHNNYEAYNKGL--RRLLLRRLLYKRADKI 142

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88784158  82 VVQNNRIKSLYiNDIDNKKLQIIPNPINPGLRPDPNVEMSNIILNVGRLERQKAQDTLIKAFANL--NPSGWELHIIGDG 159
Cdd:cd03820 143 VVLTEADKLKK-YKQPNSNVVVIPNPLSFPSEEPSTNLKSKRILAVGRLTYQKGFDLLIEAWALIakKHPDWKLRIYGDG 221

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88784158 160 RQRSYLEALIDQLHMNDKVRLLGKKKNIQPYYAKARIFVLSSLYEGFPNVLLEAMQMGKACISTDCPTGPSDIISHGDDG 239
Cdd:cd03820 222 PEREELEKLIDKLGLEDRVKLLGPTKNIAEEYANSSIFVLSSRYEGFPMVLLEAMAYGLPIISFDCPTGPSEIIEDGENG 301

                       250       260       270       280       290
                ....*....|....*....|....*....|....*....|....*....|
gi 88784158 240 ILVPVGNTAELEAALRDLIENPAKERQLGEKAKDATRPYQIENIAAVWEE 289
Cdd:cd03820 302 LLVPNGDVDALAEALLRLMEDEELRKKMGKNARKNAERFSIEKIIKQWEE 351
Glyco_trans_1_4 pfam13692
Glycosyl transferases group 1;
122-260 5.07e-45

Glycosyl transferases group 1;


Pssm-ID: 463957 [Multi-domain]  Cd Length: 138  Bit Score: 149.20  E-value: 5.07e-45
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88784158   122 NIILNVGRL-ERQKAQDTLIKAFANL--NPSGWELHIIGDGRQRsYLEALIDQLhmNDKVRLLGKKKNIQPYYAKARIFV 198
Cdd:pfam13692   2 PVILFVGRLhPNVKGVDYLLEAVPLLrkRDNDVRLVIVGDGPEE-ELEELAAGL--EDRVIFTGFVEDLAELLAAADVFV 78

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 88784158   199 LSSLYEGFPNVLLEAMQMGKACISTDCPtGPSDIIsHGDDGILVPVGNTAELEAALRDLIEN 260
Cdd:pfam13692  79 LPSLYEGFGLKLLEAMAAGLPVVATDVG-GIPELV-DGENGLLVPPGDPEALAEAILRLLED 138
RfaB COG0438
Glycosyltransferase involved in cell wall bisynthesis [Cell wall/membrane/envelope biogenesis]; ...
 181-296 5.12e-31

Glycosyltransferase involved in cell wall bisynthesis [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440207 [Multi-domain]  Cd Length: 123  Bit Score: 112.39  E-value: 5.12e-31
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88784158 181 LGKKKNIQP----YYAKARIFVLSSLYEGFPNVLLEAMQMGKACISTDCPtGPSDIISHGDDGILVPVGNTAELEAALRD 256
Cdd:COG0438   4 LVPRKGLDLlleaLLAAADVFVLPSRSEGFGLVLLEAMAAGLPVIATDVG-GLPEVIEDGETGLLVPPGDPEALAEAILR 82

                        90       100       110       120
                ....*....|....*....|....*....|....*....|.
gi 88784158 257 LIENPAKERQLGEKAKD-ATRPYQIENIAAVWEELIAELLK 296
Cdd:COG0438  83 LLEDPELRRRLGEAARErAEERFSWEAIAERLLALYEELLA 123
PRK09922 PRK09922
lipopolysaccharide 1,6-galactosyltransferase;
96-259 1.33e-26

lipopolysaccharide 1,6-galactosyltransferase;


Pssm-ID: 182148 [Multi-domain]  Cd Length: 359  Bit Score: 107.10  E-value: 1.33e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88784158   96 IDNKKLQIIPNPINPG--LRPDPNVEMSNIILNVGRL--ERQKAQDTLIKAFANLNpSGWELHIIGDGRQRSYLEALIDQ 171
Cdd:PRK09922 153 ISAQRISVIYNPVEIKtiIIPPPERDKPAVFLYVGRLkfEGQKNVKELFDGLSQTT-GEWQLHIIGDGSDFEKCKAYSRE 231

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88784158  172 LHMNDKVRLLGKKKN----IQPYYAKARIFVLSSLYEGFPNVLLEAMQMGKACISTDCPTGPSDIISHGDDGILVPVGNT 247
Cdd:PRK09922 232 LGIEQRIIWHGWQSQpwevVQQKIKNVSALLLTSKFEGFPMTLLEAMSYGIPCISSDCMSGPRDIIKPGLNGELYTPGNI 311

                        170
                 ....*....|..
gi 88784158  248 AELEAALRDLIE 259
Cdd:PRK09922 312 DEFVGKLNKVIS 323
PelF NF038011
GT4 family glycosyltransferase PelF; Proteins of this family are components of the ...
 66-266 1.23e-08

GT4 family glycosyltransferase PelF; Proteins of this family are components of the exopolysaccharide Pel transporter. It has been reported that PelF is a soluble glycosyltransferase that uses UDP-glucose as the substrate for the synthesis of exopolysaccharide Pel, whereas PelG is a Wzx-like and PST family exopolysaccharide transporter.


Pssm-ID: 411604 [Multi-domain]  Cd Length: 489  Bit Score: 55.71  E-value: 1.23e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88784158   66 LW-RF---LKKYTYRKADKLVV--QNNRIKSlyIND-IDNKKLQIIPNPIN-PGLRP-----DPNVemSNIILNVGRLER 132
Cdd:NF038011 242 LWiRFfeaLGRLCYDAADPIVAlyEGNRLRQ--IADgAPPERTRVIPNGIDlPRLAPlraqrPAGI--PPVVGLIGRVVP 317

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88784158  133 QKAQDTLIKAF---ANLNP--SGWelhIIG-DGRQRSYLE---ALIDQLHMNDKVRLLGKKKnIQPYYAKARIFVLSSLY 203
Cdd:NF038011 318 IKDIKTFIRAMrtvVRAMPeaEGW---IVGpEEEDPAYAAecrSLVASLGLQDKVKFLGFQK-IDDLLPQVGLMVLSSIS 393

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 88784158  204 EGFPNVLLEAMQMGKACISTD---CptgpSDIISHGDD--------GILVPVGNTAELEAALRDLIENPAKERQ 266
Cdd:NF038011 394 EALPLVVLEAFAAGVPVVTTDvgsC----RQLIEGLDEedralgaaGEVVAIADPQALARAALDLLRDPQRWQA 463
MSMEG_0565_glyc TIGR04047
glycosyltransferase, MSMEG_0565 family; A conserved gene cluster found sporadically from ...
 119-278 1.89e-03

glycosyltransferase, MSMEG_0565 family; A conserved gene cluster found sporadically from Actinobacteria to Proteobacteria to Cyanobacteria features a radical SAM protein, an N-acetyltransferase, an oxidoreductase, and two additional proteins whose functional classes are unclear. The metabolic role of the cluster is probably biosynthetic. This glycosyltransferase, named from member MSMEG_0565 from Mycobacterium smegmatis, occurs in most but not all instances of the cluster. [Unknown function, Enzymes of unknown specificity]


Pssm-ID: 274943 [Multi-domain]  Cd Length: 373  Bit Score: 39.30  E-value: 1.89e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88784158   119 EMSNIILNVGRLERQKAQDTLIKAFANLNPSGWELH-IIGDGRQ----RSYLEALIDQLHMND----KVRLLG--KKKNI 187
Cdd:TIGR04047 191 RGGPYVLAVGGIEPRKNTIDLLEAFALLRARRPQAQlVIAGGATlfdyDAYRREFRARAAELGvdpgPVVITGpvPDADL 270

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88784158   188 QPYYAKARIFVLSSLYEGFPNVLLEAMQMGKACISTDCPtgPSDIISHGDDGILVPVGNTAELEAALRDLIEnPAKERQL 267
Cdd:TIGR04047 271 PALYRCADAFAFPSLKEGFGLVVLEALASGIPVVASDIA--PFTEYLGRFDAAWADPSDPDSIADALALALD-PARRPAL 347

                         170
                  ....*....|.
gi 88784158   268 GEKAKDATRPY 278
Cdd:TIGR04047 348 RAAGPELAARY 358
 
Name Accession Description Interval E-value
GT4_AmsD-like cd03820
amylovoran biosynthesis glycosyltransferase AmsD and similar proteins; This family is most ...
 2-289 3.83e-91

amylovoran biosynthesis glycosyltransferase AmsD and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. AmSD in Erwinia amylovora has been shown to be involved in the biosynthesis of amylovoran, the acidic exopolysaccharide acting as a virulence factor. This enzyme may be responsible for the formation of galactose alpha-1,6 linkages in amylovoran.


Pssm-ID: 340847 [Multi-domain]  Cd Length: 351  Bit Score: 274.50  E-value: 3.83e-91
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88784158   2 ESIRNNWRLYKRVNTLIRENRIELCIGFMTTSNVLsvLASRSNGIPVVISERNNPEEEKNKLshLWRFLKKYTYRKADKL 81
Cdd:cd03820  67 KLLLKYFKKVRRLRKYLKNNKPDVVISFRTSLLTF--LALIGLKSKLIVWEHNNYEAYNKGL--RRLLLRRLLYKRADKI 142

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88784158  82 VVQNNRIKSLYiNDIDNKKLQIIPNPINPGLRPDPNVEMSNIILNVGRLERQKAQDTLIKAFANL--NPSGWELHIIGDG 159
Cdd:cd03820 143 VVLTEADKLKK-YKQPNSNVVVIPNPLSFPSEEPSTNLKSKRILAVGRLTYQKGFDLLIEAWALIakKHPDWKLRIYGDG 221

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88784158 160 RQRSYLEALIDQLHMNDKVRLLGKKKNIQPYYAKARIFVLSSLYEGFPNVLLEAMQMGKACISTDCPTGPSDIISHGDDG 239
Cdd:cd03820 222 PEREELEKLIDKLGLEDRVKLLGPTKNIAEEYANSSIFVLSSRYEGFPMVLLEAMAYGLPIISFDCPTGPSEIIEDGENG 301

                       250       260       270       280       290
                ....*....|....*....|....*....|....*....|....*....|
gi 88784158 240 ILVPVGNTAELEAALRDLIENPAKERQLGEKAKDATRPYQIENIAAVWEE 289
Cdd:cd03820 302 LLVPNGDVDALAEALLRLMEDEELRKKMGKNARKNAERFSIEKIIKQWEE 351
GT4_GT28_WabH-like cd03811
family 4 and family 28 glycosyltransferases similar to Klebsiella WabH; This family is most ...
 5-283 2.37e-68

family 4 and family 28 glycosyltransferases similar to Klebsiella WabH; This family is most closely related to the GT1 family of glycosyltransferases. WabH in Klebsiella pneumoniae has been shown to transfer a GlcNAc residue from UDP-GlcNAc onto the acceptor GalUA residue in the cellular outer core.


Pssm-ID: 340839 [Multi-domain]  Cd Length: 351  Bit Score: 216.07  E-value: 2.37e-68
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88784158   5 RNNWRLYKRVNTLIRENRIELCIGFMTTSNVLSVLASRSnGIPVVISERNNPEEEKNklSHLWRFLKKYTYRKADKLVVQ 84
Cdd:cd03811  66 LGLLKAILKLKRILKRAKPDVVISFLGFATYIVAKLAAA-RSKVIAWIHSSLSKLYY--LKKKLLLKLKLYKKADKIVCV 142

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88784158  85 NNRIKSLYIND--IDNKKLQIIPNPIN-PGLRPDPNVEMSNI------ILNVGRLERQKAQDTLIKAFANLNPSG--WEL 153
Cdd:cd03811 143 SKGIKEDLIRLgpSPPEKIEVIYNPIDiDRIRALAKEPILNEpedgpvILAVGRLDPQKGHDLLIEAFAKLRKKYpdVKL 222

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88784158 154 HIIGDGRQRSYLEALIDQLHMNDKVRLLGKKKNIQPYYAKARIFVLSSLYEGFPNVLLEAMQMGKACISTDCPtGPSDII 233
Cdd:cd03811 223 VILGDGPLREELEKLAKELGLAERVIFLGFQSNPYPYLKKADLFVLSSRYEGFPNVLLEAMALGTPVVSTDCP-GPREIL 301

                       250       260       270       280       290
                ....*....|....*....|....*....|....*....|....*....|
gi 88784158 234 SHGDDGILVPVGNTAELEAALRDLIENPAKERQLGEKAKDATRPYQIENI 283
Cdd:cd03811 302 DDGENGLLVPDGDAAALAGILAALLQKKLDAALRERLAKAQEAVFREYTI 351
GT4_CapM-like cd03808
capsular polysaccharide biosynthesis glycosyltransferase CapM and similar proteins; This ...
 3-271 6.55e-54

capsular polysaccharide biosynthesis glycosyltransferase CapM and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. CapM in Staphylococcus aureus is required for the synthesis of type 1 capsular polysaccharides.


Pssm-ID: 340837 [Multi-domain]  Cd Length: 358  Bit Score: 178.94  E-value: 6.55e-54
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88784158   3 SIRNNWRLYKRVNTLIRENRIELCIGFMTTSNVLSVLASRSNGIPVVIserNNPE------EEKNKLSHLWRFLKKYTYR 76
Cdd:cd03808  62 NPLKDLKALFKLYKLLKKEKPDIVHCHTPKPGILGRLAARLAGVPKVI---YTVHglgfvfTEGKLLRLLYLLLEKLALL 138

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88784158  77 KADKLVVQNNRIKSLYIND--IDNKKLQIIP-NPINPGL-RPDPNVEMSN--IILNVGRLERQKAQDTLIKAFANLNPSG 150
Cdd:cd03808 139 FTDKVIFVNEDDRDLAIKKgiIKKKKTVLIPgSGVDLDRfQYSPESLPSEkvVFLFVARLLKDKGIDELIEAAKILKKKG 218

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88784158 151 --WELHIIGDGRQRSYLEALIDQLHMNDKVRLLGKKKNIQPYYAKARIFVLSSLYEGFPNVLLEAMQMGKACISTDCPtG 228
Cdd:cd03808 219 pnVRFLLVGDGELENPSEILIEKLGLEGRIEFLGFRSDVPELLAESDVFVLPSYREGLPRSLLEAMAAGRPVITTDVP-G 297

                       250       260       270       280
                ....*....|....*....|....*....|....*....|...
gi 88784158 229 PSDIISHGDDGILVPVGNTAELEAALRDLIENPAKERQLGEKA 271
Cdd:cd03808 298 CRELVIDGVNGFLVPPGDVEALADAIEKLIEDPELRKEMGEAA 340
GT4_PimA-like cd03801
phosphatidyl-myo-inositol mannosyltransferase; This family is most closely related to the GT4 ...
 4-291 1.85e-50

phosphatidyl-myo-inositol mannosyltransferase; This family is most closely related to the GT4 family of glycosyltransferases and named after PimA in Propionibacterium freudenreichii, which is involved in the biosynthesis of phosphatidyl-myo-inositol mannosides (PIM) which are early precursors in the biosynthesis of lipomannans (LM) and lipoarabinomannans (LAM), and catalyzes the addition of a mannosyl residue from GDP-D-mannose (GDP-Man) to the position 2 of the carrier lipid phosphatidyl-myo-inositol (PI) to generate a phosphatidyl-myo-inositol bearing an alpha-1,2-linked mannose residue (PIM1). Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found mainly in certain bacteria and archaea.


Pssm-ID: 340831 [Multi-domain]  Cd Length: 366  Bit Score: 170.41  E-value: 1.85e-50
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88784158   4 IRNNWRLYKRVNTLIRENRIELCIGFMTTSNVLSVLASRSNGIPVVISERNNPEEEKNKLsHLW--RFLKK--YTYRKAD 79
Cdd:cd03801  64 LLRARRLLRELRPLLRLRKFDVVHAHGLLAALLAALLALLLGAPLVVTLHGAEPGRLLLL-LAAerRLLARaeALLRRAD 142

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88784158  80 KLVVQNNRIKSLYIND--IDNKKLQIIPNPINPGLRPDPNVEMSNI------ILNVGRLERQKAQDTLIKAFANLNPSG- 150
Cdd:cd03801 143 AVIAVSEALRDELRALggIPPEKIVVIPNGVDLERFSPPLRRKLGIppdrpvLLFVGRLSPRKGVDLLLEALAKLLRRGp 222

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88784158 151 -WELHIIG-DGRQRSYLEALIDQLHmnDKVRLLGK--KKNIQPYYAKARIFVLSSLYEGFPNVLLEAMQMGKACISTDCP 226
Cdd:cd03801 223 dVRLVIVGgDGPLRAELEELELGLG--DRVRFLGFvpDEELPALYAAADVFVLPSRYEGFGLVVLEAMAAGLPVVATDVG 300

                       250       260       270       280       290       300
                ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 88784158 227 tGPSDIISHGDDGILVPVGNTAELEAALRDLIENPAKERQLGEKAKDATRP-YQIENIAAVWEELI 291
Cdd:cd03801 301 -GLPEVVEDGEGGLVVPPDDVEALADALLRLLADPELRARLGRAARERVAErFSWERVAERLLDLY 365
GT4_WbnK-like cd03807
Shigella dysenteriae WbnK and similar proteins; This family is most closely related to the GT4 ...
 9-290 5.97e-47

Shigella dysenteriae WbnK and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. WbnK in Shigella dysenteriae has been shown to be involved in the type 7 O-antigen biosynthesis.


Pssm-ID: 340836 [Multi-domain]  Cd Length: 362  Bit Score: 160.95  E-value: 5.97e-47
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88784158   9 RLYKrvntLIRENRIELCIGFMTTSNVLSVLASRSN-GIPVVISERNNPEEEKNKLSHLW--RFLKKYtyrkaDKLVVQN 85
Cdd:cd03807  70 RLAK----LIRKRNPDVVHTWMYHADLIGGLAAKLAgGVKVIWSVRSSNIPQRLTRLVRKlcLLLSKF-----SPATVAN 140

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88784158  86 -NRIKSLYIND-IDNKKLQIIPNPINPG-LRPDPNVEMSN-----------IILNVGRLERQKAQDTLIKAFANLNPSG- 150
Cdd:cd03807 141 sSAVAEFHQEQgYAKNKIVVIYNGIDLFkLSPDDASRARArrrlglaedrrVIGIVGRLHPVKDHSDLLRAAALLVETHp 220

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88784158 151 -WELHIIGDGRQRSYLEALIDQLHMNDKVRLLGKKKNIQPYYAKARIFVLSSLYEGFPNVLLEAMQMGKACISTDCPtGP 229
Cdd:cd03807 221 dLRLLLVGRGPERPNLERLLLELGLEDRVHLLGERSDVPALLPAMDIFVLSSRTEGFPNALLEAMACGLPVVATDVG-GA 299

                       250       260       270       280       290       300
                ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 88784158 230 SDIISHGdDGILVPVGNTAELEAALRDLIENPAKERQLGEKAKD--ATRpYQIENIAAVWEEL 290
Cdd:cd03807 300 AELVDDG-TGFLVPAGDPQALADAIRALLEDPEKRARLGRAAREriANE-FSIDAMVRRYETL 360
Glyco_trans_1_4 pfam13692
Glycosyl transferases group 1;
122-260 5.07e-45

Glycosyl transferases group 1;


Pssm-ID: 463957 [Multi-domain]  Cd Length: 138  Bit Score: 149.20  E-value: 5.07e-45
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88784158   122 NIILNVGRL-ERQKAQDTLIKAFANL--NPSGWELHIIGDGRQRsYLEALIDQLhmNDKVRLLGKKKNIQPYYAKARIFV 198
Cdd:pfam13692   2 PVILFVGRLhPNVKGVDYLLEAVPLLrkRDNDVRLVIVGDGPEE-ELEELAAGL--EDRVIFTGFVEDLAELLAAADVFV 78

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 88784158   199 LSSLYEGFPNVLLEAMQMGKACISTDCPtGPSDIIsHGDDGILVPVGNTAELEAALRDLIEN 260
Cdd:pfam13692  79 LPSLYEGFGLKLLEAMAAGLPVVATDVG-GIPELV-DGENGLLVPPGDPEALAEAILRLLED 138
GT4_WlbH-like cd03798
Bordetella parapertussis WlbH and similar proteins; This family is most closely related to the ...
 29-271 2.83e-44

Bordetella parapertussis WlbH and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. Staphylococcus aureus CapJ may be involved in capsule polysaccharide biosynthesis. WlbH in Bordetella parapertussis has been shown to be required for the biosynthesis of a trisaccharide that, when attached to the B. pertussis lipopolysaccharide (LPS) core (band B), generates band A LPS.


Pssm-ID: 340828 [Multi-domain]  Cd Length: 376  Bit Score: 154.46  E-value: 2.83e-44
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88784158  29 FMTTSNVLSVLASRSNGIPVVISERNNPEEEkNKLSHLWRFLKKYTYRKADKLVVQNNRIKSLYIN-DIDNKKLQIIPNP 107
Cdd:cd03798 103 FAYPAGFAAALLARLYGVPYVVTEHGSDINV-FPPRSLLRKLLRWALRRAARVIAVSKALAEELVAlGVPRDRVDVIPNG 181

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88784158 108 IN-----PGLRPDPNVEMSNIILNVGRLERQKAQDTLIKAFANLNPS--GWELHIIGDGRQRSYLEALIDQLHMNDKVRL 180
Cdd:cd03798 182 VDparfqPEDRGLGLPLDAFVILFVGRLIPRKGIDLLLEAFARLAKArpDVVLLIVGDGPLREALRALAEDLGLGDRVTF 261

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88784158 181 LGK--KKNIQPYYAKARIFVLSSLYEGFPNVLLEAMQMGKACISTDCpTGPSDIISHGDDGILVPVGNTAELEAALRDLI 258
Cdd:cd03798 262 TGRlpHEQVPAYYRACDVFVLPSRHEGFGLVLLEAMACGLPVVATDV-GGIPEVVGDPETGLLVPPGDADALAAALRRAL 340

                       250
                ....*....|...
gi 88784158 259 ENPAKeRQLGEKA 271
Cdd:cd03798 341 AEPYL-RELGEAA 352
Glycos_transf_1 pfam00534
Glycosyl transferases group 1; Mutations in this domain of Swiss:P37287 lead to disease ...
 122-272 1.01e-39

Glycosyl transferases group 1; Mutations in this domain of Swiss:P37287 lead to disease (Paroxysmal Nocturnal haemoglobinuria). Members of this family transfer activated sugars to a variety of substrates, including glycogen, Fructose-6-phosphate and lipopolysaccharides. Members of this family transfer UDP, ADP, GDP or CMP linked sugars. The eukaryotic glycogen synthases may be distant members of this family.


Pssm-ID: 425737 [Multi-domain]  Cd Length: 158  Bit Score: 136.25  E-value: 1.01e-39
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88784158   122 NIILNVGRLERQKAQDTLIKAFANLNPSG--WELHIIGDGRQRSYLEALIDQLHMNDKVRLLGKKKNIQP--YYAKARIF 197
Cdd:pfam00534   3 KIILFVGRLEPEKGLDLLIKAFALLKEKNpnLKLVIAGDGEEEKRLKKLAEKLGLGDNVIFLGFVSDEDLpeLLKIADVF 82

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 88784158   198 VLSSLYEGFPNVLLEAMQMGKACISTDCPtGPSDIISHGDDGILVPVGNTAELEAALRDLIENPAKERQLGEKAK 272
Cdd:pfam00534  83 VLPSRYEGFGIVLLEAMACGLPVIASDVG-GPPEVVKDGETGFLVKPNNAEALAEAIDKLLEDEELRERLGENAR 156
GT4_WavL-like cd03819
Vibrio cholerae WavL and similar sequences; This family is most closely related to the GT4 ...
 3-282 7.85e-38

Vibrio cholerae WavL and similar sequences; This family is most closely related to the GT4 family of glycosyltransferases. WavL in Vibrio cholerae has been shown to be involved in the biosynthesis of the lipopolysaccharide core.


Pssm-ID: 340846 [Multi-domain]  Cd Length: 345  Bit Score: 136.72  E-value: 7.85e-38
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88784158   3 SIRNNWRLYKRvntLIRENRIELCIGFMTTSNVLSVLASRSNGIPVVISERNNPEEEKNKLSHLWRFLKKytyrkADKLV 82
Cdd:cd03819  60 RALLGNVRLAR---LIRRERIDLIHAHSRAPAWLGWLASRLTGVPLVTTVHGSYLATYHPKDFALAVRAR-----GDRVI 131

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88784158  83 VQNNRIKSLYINDI--DNKKLQIIPNPINPGLRPDPNVEMSN----------IILNVGRLERQKAQDTLIKAFANLNPS- 149
Cdd:cd03819 132 AVSELVRDHLIEALgvDPERIRVIPNGVDTDRFPPEAEAEERaqlglpegkpVVGYVGRLSPEKGWLLLVDAAAELKDEp 211

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88784158 150 GWELHIIGDGRQRSYLEALIDQLHMNDKVRLLGKKKNIQPYYAKARIFVLSSLYEGFPNVLLEAMQMGKACISTDcPTGP 229
Cdd:cd03819 212 DFRLLVAGDGPERDEIRRLVERLGLRDRVTFTGFREDVPAALAASDVVVLPSLHEEFGRVALEAMACGTPVVATD-VGGA 290

                       250       260       270       280       290
                ....*....|....*....|....*....|....*....|....*....|...
gi 88784158 230 SDIISHGDDGILVPVGNTAELEAALRDLIENPaKERQLGEKAKDATRPYQIEN 282
Cdd:cd03819 291 REIVVHGRTGLLVPPGDAEALADAIRAAKLLP-EAREKLQAAAALTEAVRELL 342
GT4_UGDG-like cd03817
UDP-Glc:1,2-diacylglycerol 3-a-glucosyltransferase and similar proteins; This family is most ...
 68-290 7.16e-33

UDP-Glc:1,2-diacylglycerol 3-a-glucosyltransferase and similar proteins; This family is most closely related to the GT1 family of glycosyltransferases. UDP-glucose-diacylglycerol glucosyltransferase (EC 2.4.1.337, UGDG; also known as 1,2-diacylglycerol 3-glucosyltransferase) catalyzes the transfer of glucose from UDP-glucose to 1,2-diacylglycerol forming 3-D-glucosyl-1,2-diacylglycerol.


Pssm-ID: 340844 [Multi-domain]  Cd Length: 372  Bit Score: 123.93  E-value: 7.16e-33
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88784158  68 RFLKKYtYRKADKLVVQNNRIKSLYINDIDNKKLQIIPNPINP---------------GLRPDPNvemsnIILNVGRLER 132
Cdd:cd03817 139 KLVRRF-YNHTDAVIAPSEKIKDTLREYGVKGPIEVIPNGIDLdkfekplnteerrklGLPPDEP-----ILLYVGRLAK 212

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88784158 133 QKAQDTLIKAFANLN-PSGWELHIIGDGRQRSYLEALIDQLHMNDKVRLLGKKKN--IQPYYAKARIFVLSSLYEGFPNV 209
Cdd:cd03817 213 EKNIDFLLRAFAELKkEPNIKLVIVGDGPEREELKELARELGLADKVIFTGFVPReeLPEYYKAADLFVFASTTETQGLV 292

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88784158 210 LLEAMQMGKACISTDcPTGPSDIISHGDDGILVPVGNtAELEAALRDLIENPAKERQLGEKAKDATRPYQI-ENIAAVWE 288
Cdd:cd03817 293 YLEAMAAGLPVVAAK-DPAASELVEDGENGFLFEPND-ETLAEKLLHLRENLELLRKLSKNAEISAREFAFaKSVEKLYE 370


                ..
gi 88784158 289 EL 290
Cdd:cd03817 371 EV 372
RfaB COG0438
Glycosyltransferase involved in cell wall bisynthesis [Cell wall/membrane/envelope biogenesis]; ...
 181-296 5.12e-31

Glycosyltransferase involved in cell wall bisynthesis [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440207 [Multi-domain]  Cd Length: 123  Bit Score: 112.39  E-value: 5.12e-31
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88784158 181 LGKKKNIQP----YYAKARIFVLSSLYEGFPNVLLEAMQMGKACISTDCPtGPSDIISHGDDGILVPVGNTAELEAALRD 256
Cdd:COG0438   4 LVPRKGLDLlleaLLAAADVFVLPSRSEGFGLVLLEAMAAGLPVIATDVG-GLPEVIEDGETGLLVPPGDPEALAEAILR 82

                        90       100       110       120
                ....*....|....*....|....*....|....*....|.
gi 88784158 257 LIENPAKERQLGEKAKD-ATRPYQIENIAAVWEELIAELLK 296
Cdd:COG0438  83 LLEDPELRRRLGEAARErAEERFSWEAIAERLLALYEELLA 123
GT4_GtfA-like cd04949
accessory Sec system glycosyltransferase GtfA and similar proteins; This family is most ...
 121-287 8.67e-29

accessory Sec system glycosyltransferase GtfA and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases and is named after gtfA in Streptococcus gordonii, where it plays a role in the O-linked glycosylation of GspB, a cell surface glycoprotein involved in platelet binding. In general glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found in bacteria.


Pssm-ID: 340855 [Multi-domain]  Cd Length: 328  Bit Score: 112.39  E-value: 8.67e-29
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88784158 121 SNIILNVGRLERQKAQDTLIKAFANLNPSGWE--LHIIGDGRQRSYLEALIDQLHMNDKVRLLGKKKNIQPYYAKARIFV 198
Cdd:cd04949 160 SNKIITISRLAPEKQLDHLIEAVAKAVKKVPEitLDIYGYGEEREKLKKLIEELHLEDNVFLKGYHSNLDQEYQDAYLSL 239

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88784158 199 LSSLYEGFPNVLLEAMQMGKACISTDCPTGPSDIISHGDDGILVPVGNTAELEAALRDLIENPAKERQLGEKAKDATRPY 278
Cdd:cd04949 240 LTSQMEGFGLTLMEAIGHGLPVVSYDVKYGPSELIEDGENGYLIEKNNIDALADKIIELLNDPEKLQQFSEESYKIAEKY 319


                ....*....
gi 88784158 279 QIENIAAVW 287
Cdd:cd04949 320 STENVMEKW 328
GT4_WfcD-like cd03795
Escherichia coli alpha-1,3-mannosyltransferase WfcD and similar proteins; This family is most ...
 62-272 3.10e-28

Escherichia coli alpha-1,3-mannosyltransferase WfcD and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP-linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found mainly in bacteria and eukaryotes.


Pssm-ID: 340826 [Multi-domain]  Cd Length: 355  Bit Score: 111.21  E-value: 3.10e-28
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88784158  62 KLSHLWRFLKKYTYRKADKLVVQ--NNRIKSLYINDIDNKKlQIIPNPINPGLRPDPNVEMSN---------IILNVGRL 130
Cdd:cd03795 122 KLLKLYKPLMTRFLRRADRIIATspNYVETSPTLREFKNKV-RVIPLGIDKNVYNIPRVDFENikrekkgkkIFLFIGRL 200

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88784158 131 ERQKAQDTLIKAFANLNPSGWelhIIGDGRQRSYLEALIDqLHMNDKVRLLG----KKKNIqpYYAKARIFVLSSLY--E 204
Cdd:cd03795 201 VYYKGLDYLIEAAQYLNYPIV---IGGEGPLKPDLEAQIE-LNLLDNVKFLGrvddEEKVI--YLHLCDVFVFPSVLrsE 274

                       170       180       190       200       210       220
                ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 88784158 205 GFPNVLLEAMQMGKACISTDCPTGPSDIISHGDDGILVPVGNTAELEAALRDLIENPAKERQLGEKAK 272
Cdd:cd03795 275 AFGIVLLEAMMCGKPVISTNIGTGVPYVNNNGETGLVVPPKDPDALAEAIDKLLSDEELRESYGENAK 342
GT4-like cd03813
glycosyltransferase family 4 proteins; This family is most closely related to the GT4 family ...
 36-272 3.40e-28

glycosyltransferase family 4 proteins; This family is most closely related to the GT4 family of glycosyltransferases. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found mainly in bacteria, while some of them are also found in Archaea and eukaryotes.


Pssm-ID: 340841 [Multi-domain]  Cd Length: 474  Bit Score: 112.81  E-value: 3.40e-28
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88784158  36 LSVLASRSNGIPVVISE-----RNNPEEEKNKLSH------LW-RF---LKKYTYRKADKLVVQNNRIKSLYIND-IDNK 99
Cdd:cd03813 188 LGALARHRRGIPFLLTEhgiytRERKIEILQSTWImgyikkLWiRFferLGKLAYQQADKIISLYEGNRRRQIRLgADPD 267

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88784158 100 KLQIIPNPIN-----PGLRPDPNVEMSNIILnVGRLERQKAQDTLIKAFANL--NPSGWELHIIG--DGRQRSYLEA--L 168
Cdd:cd03813 268 KTRVIPNGIDiqrfaPAREERPEKEPPVVGL-VGRVVPIKDVKTFIRAFKLVrrAMPDAEGWLIGpeDEDPEYAQECkrL 346

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88784158 169 IDQLHMNDKVRLLGKKkNIQPYYAKARIFVLSSLYEGFPNVLLEAMQMGKACISTD---CPtgpsDIISHGDD-----GI 240
Cdd:cd03813 347 VASLGLENKVKFLGFQ-NIKEYYPKLGLLVLTSISEGQPLVILEAMASGVPVVATDvgsCR----ELIYGADDalgqaGL 421

                       250       260       270
                ....*....|....*....|....*....|..
gi 88784158 241 LVPVGNTAELEAALRDLIENPAKERQLGEKAK 272
Cdd:cd03813 422 VVPPADPEALAEALIKLLRDPELRQAFGEAGR 453
GT4_MtfB-like cd03809
glycosyltransferases MtfB, WbpX, and similar proteins; This family is most closely related to ...
 56-284 5.98e-28

glycosyltransferases MtfB, WbpX, and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. MtfB (mannosyltransferase B) in E. coli has been shown to direct the growth of the O9-specific polysaccharide chain. It transfers two mannoses into the position 3 of the previously synthesized polysaccharide.


Pssm-ID: 340838 [Multi-domain]  Cd Length: 362  Bit Score: 110.53  E-value: 5.98e-28
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88784158  56 PEEEKNKLSHLWRFLKKYTYRKADK-LVVQN---NRIKSLYinDIDNKKLQIIPNPINPGLRPDPNVEM--------SNI 123
Cdd:cd03809 117 PEFFPKRFRLYYRLLLPISLRRADAiITVSEatrDDIIKFY--GVPPEKIVVIPLGVDPSFFPPESAAVliakyllpEPY 194

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88784158 124 ILNVGRLERQKAQDTLIKAFANLNPSG--WELHIIG-DGRQRSYLEALIDQLHMNDKVRLLGK--KKNIQPYYAKARIFV 198
Cdd:cd03809 195 FLYVGTLEPRKNHERLLKAFALLKKQGgdLKLVIVGgKGWEDEELLDLVKKLGLGGRVRFLGYvsDEDLPALYRGARAFV 274

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88784158 199 LSSLYEGFPNVLLEAMQMGKACIStdcptgpSDIISH----GDDGILVPVGNTAELEAALRDLIENPAKERQLGEKAKDA 274
Cdd:cd03809 275 FPSLYEGFGLPVLEAMACGTPVIA-------SNISVLpevaGDAALYFDPLDPESIADAILRLLEDPSLREELIRKGLER 347

                       250
                ....*....|
gi 88784158 275 TRPYQIENIA 284
Cdd:cd03809 348 AKKFSWEKTA 357
GT4_ExpE7-like cd03823
glycosyltransferase ExpE7 and similar proteins; This family is most closely related to the GT4 ...
 7-262 1.51e-27

glycosyltransferase ExpE7 and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. ExpE7 in Sinorhizobium meliloti has been shown to be involved in the biosynthesis of galactoglucans (exopolysaccharide II).


Pssm-ID: 340850 [Multi-domain]  Cd Length: 357  Bit Score: 109.34  E-value: 1.51e-27
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88784158   7 NWRLYKRVNTLIRENRIELcIGFMTTSNV-LSVL-ASRSNGIPVVISERNNPeeeknkLSHLWRFLkkytYRKADKLVVQ 84
Cdd:cd03823  81 NPGLRRLLARLLEDFRPDV-VHTHNLSGLgASLLdAARDLGIPVVHTLHDYW------LLCPRQFL----FKKGGDAVLA 149

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88784158  85 N-NRIKSLYI-NDIDNKKLQIIPNPINPGLRPDPNVEMSNIILNV---GRLERQKAQDTLIKAFANLNPSGWELHIIGDG 159
Cdd:cd03823 150 PsRFTANLHEaNGLFSARISVIPNAVEPDLAPPPRRRPGTERLRFgyiGRLTEEKGIDLLVEAFKRLPREDIELVIAGHG 229

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88784158 160 RQRSYLEALIDqlhmnDKVRLLGK--KKNIQPYYAKARIFVLSSL-YEGFPNVLLEAMQMGKACISTDcPTGPSDIISHG 236
Cdd:cd03823 230 PLSDERQIEGG-----RRIAFLGRvpTDDIKDFYEKIDVLVVPSIwPEPFGLVVREAIAAGLPVIASD-LGGIAELIQPG 303

                       250       260
                ....*....|....*....|....*.
gi 88784158 237 DDGILVPVGNTAELEAALRDLIENPA 262
Cdd:cd03823 304 VNGLLFAPGDAEDLAAAMRRLLTDPA 329
PRK09922 PRK09922
lipopolysaccharide 1,6-galactosyltransferase;
96-259 1.33e-26

lipopolysaccharide 1,6-galactosyltransferase;


Pssm-ID: 182148 [Multi-domain]  Cd Length: 359  Bit Score: 107.10  E-value: 1.33e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88784158   96 IDNKKLQIIPNPINPG--LRPDPNVEMSNIILNVGRL--ERQKAQDTLIKAFANLNpSGWELHIIGDGRQRSYLEALIDQ 171
Cdd:PRK09922 153 ISAQRISVIYNPVEIKtiIIPPPERDKPAVFLYVGRLkfEGQKNVKELFDGLSQTT-GEWQLHIIGDGSDFEKCKAYSRE 231

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88784158  172 LHMNDKVRLLGKKKN----IQPYYAKARIFVLSSLYEGFPNVLLEAMQMGKACISTDCPTGPSDIISHGDDGILVPVGNT 247
Cdd:PRK09922 232 LGIEQRIIWHGWQSQpwevVQQKIKNVSALLLTSKFEGFPMTLLEAMSYGIPCISSDCMSGPRDIIKPGLNGELYTPGNI 311

                        170
                 ....*....|..
gi 88784158  248 AELEAALRDLIE 259
Cdd:PRK09922 312 DEFVGKLNKVIS 323
GT4_WbdM_like cd04951
LPS/UnPP-GlcNAc-Gal a-1,4-glucosyltransferase WbdM and similar proteins; This family is most ...
 69-290 5.19e-24

LPS/UnPP-GlcNAc-Gal a-1,4-glucosyltransferase WbdM and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases and is named after WbdM in Escherichia coli. In general glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found in bacteria.


Pssm-ID: 340857 [Multi-domain]  Cd Length: 360  Bit Score: 99.83  E-value: 5.19e-24
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88784158  69 FLKKYTYRKADKLVVQNNRIKSLYINDIDNKklQIIPNPINpgLRPDPNVemsniILNVGRLERQKAQDTLIKAFANLNP 148
Cdd:cd04951 145 FIAKKAFSKNKSVPVYNGIDLNKFKKDINVR--LKIRNKLN--LKNDEFV-----ILNVGRLTEAKDYPNLLLAISELIL 215

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88784158 149 SG--WELHIIGDGRQRSYLEALIDQLHMNDKVRLLGKKKNIQPYYAKARIFVLSSLYEGFPNVLLEAMQMGKACISTDCp 226
Cdd:cd04951 216 SKndFKLLIAGDGPLRNELERLICNLNLVDRVILLGQISNISEYYNAADLFVLSSEWEGFGLVVAEAMACERPVVATDA- 294

                       170       180       190       200       210       220
                ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 88784158 227 TGPSDIISHGDDgiLVPVGNTAELEAALRDLIENPAKER-QLGEKAKDATRPYQIENIAAVWEEL 290
Cdd:cd04951 295 GGVAEVVGDHNY--VVPVSDPQLLAEKIKEIFDMSDEERdILGNKNEYIAKNFSINTIVNEWERL 357
Glycosyltransferase_GTB-type cd01635
glycosyltransferase family 1 and related proteins with GTB topology; Glycosyltransferases ...
 125-242 1.75e-22

glycosyltransferase family 1 and related proteins with GTB topology; Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. The structures of the formed glycoconjugates are extremely diverse, reflecting a wide range of biological functions. The members of this family share a common GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility.


Pssm-ID: 340816 [Multi-domain]  Cd Length: 235  Bit Score: 93.24  E-value: 1.75e-22
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88784158 125 LNVGRLERQKAQDTLIKAFANLNP--SGWELHIIGDGRQRSYLEALIDQLHMNDKVRLLGK---KKNIQPYYAKARIFVL 199
Cdd:cd01635 114 VSVGRLVPEKGIDLLLEALALLKArlPDLVLVLVGGGGEREEEEALAAALGLLERVVIIGGlvdDEVLELLLAAADVFVL 193

                        90       100       110       120
                ....*....|....*....|....*....|....*....|...
gi 88784158 200 SSLYEGFPNVLLEAMQMGKACISTDCPtGPSDIISHGDDGILV 242
Cdd:cd01635 194 PSRSEGFGLVLLEAMAAGKPVIATDVG-GIPEFVVDGENGLLV 235
GT4-like cd03814
glycosyltransferase family 4 proteins; This family is most closely related to the GT4 family ...
 105-295 2.16e-22

glycosyltransferase family 4 proteins; This family is most closely related to the GT4 family of glycosyltransferases and includes a sequence annotated as alpha-D-mannose-alpha(1-6)phosphatidyl myo-inositol monomannoside transferase from Bacillus halodurans. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found mainly in bacteria and eukaryotes.


Pssm-ID: 340842 [Multi-domain]  Cd Length: 365  Bit Score: 95.44  E-value: 2.16e-22
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88784158 105 PNPINPGLRPDPNVEMSNIILNVGRLERQKAQDTLIKAFANLNPS-GWELHIIGDGRQRSYLEalidqlHMNDKVRLLGK 183
Cdd:cd03814 182 PSRRDAALRRRLGPPGRPLLLYVGRLAPEKNLEALLDADLPLAASpPVRLVVVGDGPARAELE------ARGPDVIFTGF 255

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88784158 184 KK--NIQPYYAKARIFVLSSLYEGFPNVLLEAMQMGKACISTDCPtGPSDIISHGDDGILVPVGNTAELEAALRDLIENP 261
Cdd:cd03814 256 LTgeELARAYASADVFVFPSRTETFGLVVLEAMASGLPVVAADAG-GPRDIVRPGGTGALVEPGDAAAFAAALRALLEDP 334

                       170       180       190
                ....*....|....*....|....*....|....
gi 88784158 262 AKERQLGEKAKDATRPYQieniaavWEELIAELL 295
Cdd:cd03814 335 ELRRRMAARARAEAERYS-------WEAFLDNLL 361
GT4_WcaC-like cd03825
putative colanic acid biosynthesis glycosyl transferase WcaC and similar proteins; This family ...
 53-294 5.56e-22

putative colanic acid biosynthesis glycosyl transferase WcaC and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. Escherichia coli WcaC has been predicted to function in colanic acid biosynthesis. WcfI in Bacteroides fragilis has been shown to be involved in the capsular polysaccharide biosynthesis.


Pssm-ID: 340851 [Multi-domain]  Cd Length: 364  Bit Score: 94.32  E-value: 5.56e-22
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88784158  53 RNNPEEEKNKLSHLWRfLKKYTYRKADKLVVqnnrIKSLYINDIDN-------KKLQIIPNPIN---------PGLRPDP 116
Cdd:cd03825 113 NSYPPAKKDLSRQLFR-RKREALAKKRLTIV----APSRWLADMVRrspllkgLPVVVIPNGIDteifapvdkAKARKRL 187

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88784158 117 NVEM-SNIILNVGR--LERQKAQDTLIKAFANLNP-SGWELHIIGDGRQRSyLEALIDQLHM---NDKVRLLgkkkniqP 189
Cdd:cd03825 188 GIPQdKKVILFGAEsvTKPRKGFDELIEALKLLATkDDLLLVVFGKNDPQI-VILPFDIISLgyiDDDEQLV-------D 259

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88784158 190 YYAKARIFVLSSLYEGFPNVLLEAMQMGKACISTDCpTGPSDIISHGDDGILVPVGNTAELEAALRDLIENPAKERQLGE 269
Cdd:cd03825 260 IYSAADLFVHPSLADNLPNTLLEAMACGTPVVAFDT-GGSPEIVQHGVTGYLVPPGDVQALAEAIEWLLANPKERESLGE 338

                       250       260
                ....*....|....*....|....*.
gi 88784158 270 KAKD-ATRPYQIENIAAVWEELIAEL 294
Cdd:cd03825 339 RARAlAENHFDQRVQAQRYLELYKDL 364
GT4_sucrose_synthase cd03800
sucrose-phosphate synthase and similar proteins; This family is most closely related to the ...
 123-295 8.89e-22

sucrose-phosphate synthase and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. The sucrose-phosphate synthases in this family may be unique to plants and photosynthetic bacteria. This enzyme catalyzes the synthesis of sucrose 6-phosphate from fructose 6-phosphate and uridine 5'-diphosphate-glucose, a key regulatory step of sucrose metabolism. The activity of this enzyme is regulated by phosphorylation and moderated by the concentration of various metabolites and light.


Pssm-ID: 340830 [Multi-domain]  Cd Length: 398  Bit Score: 93.84  E-value: 8.89e-22
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88784158 123 IILNVGRLERQKAQDTLIKAFANLNPSGW--ELHIIGDGR------QRSYLEALIDQLHMNDKVRLLG--KKKNIQPYYA 192
Cdd:cd03800 222 VVLALGRLDPRKGIDTLVRAFAQLPELRElaNLVLVGGPSddplsmDREELAELAEELGLIDRVRFPGrvSRDDLPELYR 301

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88784158 193 KARIFVLSSLYEGFPNVLLEAMQMGKACISTdCPTGPSDIISHGDDGILVPVGNTAELEAALRDLIENPAKERQLGEKAk 272
Cdd:cd03800 302 AADVFVVPSLYEPFGLTAIEAMACGTPVVAT-AVGGLQDIVRDGRTGLLVDPHDPEALAAALRRLLDDPALWQRLSRAG- 379

                       170       180
                ....*....|....*....|....*
gi 88784158 273 datrpyqIENIAAV--WEELIAELL 295
Cdd:cd03800 380 -------LERARAHytWESVADQLL 397
GT4_CapH-like cd03812
capsular polysaccharide biosynthesis glycosyltransferase CapH and similar proteins; This ...
 6-234 1.70e-20

capsular polysaccharide biosynthesis glycosyltransferase CapH and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. capH in Staphylococcus aureus has been shown to be required for the biosynthesis of the type 1 capsular polysaccharide (CP1).


Pssm-ID: 340840 [Multi-domain]  Cd Length: 357  Bit Score: 90.04  E-value: 1.70e-20
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88784158   6 NNWRLYKRVNTLIRENRIELCIGFMTTSNVLSVLASRSNGIPVVIS-ERNNPEEEKNKLSHLWRFLKKYTYRKADKLVVQ 84
Cdd:cd03812  64 NIIKYFIKLLKLIKKEKYDIVHVHGSSSNGIILLLAAKAGVPVRIAhSHNTKDSSIKLRKIRKNVLKKLIERLSTKYLAC 143

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88784158  85 NNRI-KSLYiNDIDNKKLQIIPNPI-------NPGLRPD---PNVEMSNIIL-NVGRLERQKAQDTLIKAFANL--NPSG 150
Cdd:cd03812 144 SEDAgEWLF-GEVENGKFKVIPNGIdiekykfNKEKRRKrrkLLILEDKLVLgHVGRFNEQKNHSFLIDIFEELkkKNPN 222

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88784158 151 WELHIIGDGRQRSYLEALIDQLHMNDKVRLLGKKKNIQPYYAKARIFVLSSLYEGFPNVLLEAMQMGKACISTDCPTGPS 230
Cdd:cd03812 223 VKLVLVGEGELKEKIKEKVKELGLEDKVIFLGFRNDVSEILSAMDVFLFPSLYEGLPLVAVEAQASGLPCLLSDTITKEC 302


                ....
gi 88784158 231 DIIS 234
Cdd:cd03812 303 DITN 306
GT4_Bme6-like cd03821
Brucella melitensis Bme6 and similar proteins; This family is most closely related to the GT4 ...
 103-284 4.96e-20

Brucella melitensis Bme6 and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. Bme6 in Brucella melitensis has been shown to be involved in the biosynthesis of a polysaccharide.


Pssm-ID: 340848 [Multi-domain]  Cd Length: 377  Bit Score: 88.97  E-value: 4.96e-20
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88784158 103 IIPNPIN-----PGLRPDPNV---EMSNIILNVGRLERQKAQDTLIKAFANLNPSG--WELHIIG-DGRQRSYLEALIDQ 171
Cdd:cd03821 178 VIPNGVDipefdPGLRDRRKHnglEDRRIILFLGRIHPKKGLDLLIRAARKLAEQGrdWHLVIAGpDDGAYPAFLQLQSS 257

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88784158 172 LHMNDKVRLLG----KKKNIQpyYAKARIFVLSSLYEGFPNVLLEAMQMG-KACISTDCPTgpSDIISHGDDGILVPvgN 246
Cdd:cd03821 258 LGLGDRVTFTGplygEAKWAL--YASADLFVLPSYSENFGNVVAEALACGlPVVITDKCGL--SELVEAGCGVVVDP--N 331

                       170       180       190       200
                ....*....|....*....|....*....|....*....|.
gi 88784158 247 TAELEAALRDLIENPAKERQLGE---KAKDATRPYQIENIA 284
Cdd:cd03821 332 VSSLAEALAEALRDPADRKRLGEmarRARQVEENFSWEAVA 372
GT4_BshA-like cd04962
N-acetyl-alpha-D-glucosaminyl L-malate synthase BshA and similar proteins; This family is most ...
 69-294 9.84e-20

N-acetyl-alpha-D-glucosaminyl L-malate synthase BshA and similar proteins; This family is most closely related to the GT1 family of glycosyltransferases. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found mainly in bacteria, while some of them are also found in Archaea and eukaryotes.


Pssm-ID: 340859 [Multi-domain]  Cd Length: 370  Bit Score: 87.79  E-value: 9.84e-20
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88784158  69 FLKKYTYRKADKlvvqNNRIKSLYiNDIDNKKLQIIPNPINPGLRPDPNVEmsNIILNVGRLERQKAQDTLIKAFANLN- 147
Cdd:cd04962 151 SLRQETYELFDV----DKDIEVIH-NFIDEDVFKRKPAGALKRRLLAPPDE--KVVIHVSNFRPVKRIDDVVRVFARVRr 223

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88784158 148 --PSgwELHIIGDGRQRSYLEALIDQLHMNDKVRLLGKKKNIQPYYAKARIFVLSSLYEGFPNVLLEAMQMGKACISTDC 225
Cdd:cd04962 224 kiPA--KLLLVGDGPERVPAEELARELGVEDRVLFLGKQDDVEELLSIADLFLLPSEKESFGLAALEAMACGVPVVSSNA 301

                       170       180       190       200       210       220       230
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88784158 226 pTGPSDIISHGDDGILVPVGNTAELEAALRDLIENPAKERQLGEKA-KDATRPYQIENIAAVWEELIAEL 294
Cdd:cd04962 302 -GGIPEVVKHGETGFLSDVGDVDAMAKSALSILEDDELYNRMGRAArKRAAERFDPERIVPQYEAYYRRL 370
GT4_AmsK-like cd03799
Erwinia amylovora AmsK and similar proteins; This is a family of GT4 glycosyltransferases ...
 124-262 1.23e-19

Erwinia amylovora AmsK and similar proteins; This is a family of GT4 glycosyltransferases found specifically in certain bacteria. AmsK in Erwinia amylovora, has been reported to be involved in the biosynthesis of amylovoran, a exopolysaccharide acting as a virulence factor.


Pssm-ID: 340829 [Multi-domain]  Cd Length: 350  Bit Score: 87.51  E-value: 1.23e-19
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88784158 124 ILNVGRLERQKAQDTLIKAFANLNPSG--WELHIIGDGRQRSYLEALIDQLHMNDKVRLLGKKKN--IQPYYAKARIFVL 199
Cdd:cd03799 177 ILTVGRLTEKKGLEYAIEAVAKLAQKYpnIEYQIIGDGDLKEQLQQLIQELNIGDCVKLLGWKPQeeIIEILDEADIFIA 256

                        90       100       110       120       130       140
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 88784158 200 SSL------YEGFPNVLLEAMQMGKACISTDcPTGPSDIISHGDDGILVPVGNTAELEAALRDLIENPA 262
Cdd:cd03799 257 PSVtaadgdQDGPPNTLKEAMAMGLPVISTE-HGGIPELVEDGVSGFLVPERDAEAIAEKLTYLIEHPA 324
GT4_WbuB-like cd03794
Escherichia coli WbuB and similar proteins; This family is most closely related to the GT1 ...
 32-274 4.52e-19

Escherichia coli WbuB and similar proteins; This family is most closely related to the GT1 family of glycosyltransferases. WbuB in E. coli is involved in the biosynthesis of the O26 O-antigen. It has been proposed to function as an N-acetyl-L-fucosamine (L-FucNAc) transferase.


Pssm-ID: 340825 [Multi-domain]  Cd Length: 391  Bit Score: 86.24  E-value: 4.52e-19
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88784158  32 TSNVLSVLASRSNGIPVVI--------SERNNPEEEKNKLSHLWRFLKKYTYRKADKLVVQNNRIKSLYIN-DIDNKKLQ 102
Cdd:cd03794 110 TLGLAALLLKKLRGAPFILdvrdlwpeSLIALGVLKKGSLLKLLKKLERKLYRLADAIIVLSPGLKEYLLRkGVPKEKII 189

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88784158 103 IIPNPINPGLRPDPNVEMSN---------IILNVGRLERQKAQDTLIKAFANL-NPSGWELHIIGDGRQRSYLEALIDQL 172
Cdd:cd03794 190 VIPNWADLEEFKPPPKDELRkklglddkfVVVYAGNIGKAQGLETLLEAAERLkRRPDIRFLFVGDGDEKERLKELAKAR 269

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88784158 173 HMnDKVRLLGK--KKNIQPYYAKARIFVLS-----SLYEGFPNVLLEAMQMGKACISTDcPTGPSDIISHGDDGILVPVG 245
Cdd:cd03794 270 GL-DNVTFLGRvpKEEVPELLSAADVGLVPlkdnpANRGSSPSKLFEYMAAGKPILASD-DGGSDLAVEINGCGLVVEPG 347

                       250       260
                ....*....|....*....|....*....
gi 88784158 246 NTAELEAALRDLIENPAKERQLGEKAKDA 274
Cdd:cd03794 348 DPEALADAILELLDDPELRRAMGENGREL 376
GT4-like cd05844
glycosyltransferase family 4 proteins; Glycosyltransferases catalyze the transfer of sugar ...
 100-288 8.45e-19

glycosyltransferase family 4 proteins; Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to glycosyltransferase family 4 (GT4). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility.


Pssm-ID: 340860 [Multi-domain]  Cd Length: 365  Bit Score: 85.20  E-value: 8.45e-19
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88784158 100 KLQIIPNPINPG-LRPDPNVEMSNIILNVGRLERQKAQDTLIKAFANLNPSGWE--LHIIGDGRQRSYLEALIDQLhmnD 176
Cdd:cd05844 167 RIHVHYIGIDPAkFAPRDPAERAPTILFVGRLVEKKGCDVLIEAFRRLAARHPTarLVIAGDGPLRPALQALAAAL---G 243

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88784158 177 KVRLLGK--KKNIQPYYAKARIFVLSSLY------EGFPNVLLEAMQMGKACISTDcPTGPSDIISHGDDGILVPVGNTA 248
Cdd:cd05844 244 RVRFLGAlpHAEVQDWMRRAEIFCLPSVTaasgdsEGLGIVLLEAAACGVPVVSSR-HGGIPEAILDGETGFLVPEGDVD 322

                       170       180       190       200
                ....*....|....*....|....*....|....*....|.
gi 88784158 249 ELEAALRDLIENPAKERQLGEKAKD-ATRPYQIENIAAVWE 288
Cdd:cd05844 323 ALADALQALLADRALADRMGGAARAfVCEQFDIRVQTAKLE 363
PRK15490 PRK15490
Vi polysaccharide biosynthesis glycosyltransferase TviE;
96-255 9.25e-10

Vi polysaccharide biosynthesis glycosyltransferase TviE;


Pssm-ID: 185387 [Multi-domain]  Cd Length: 578  Bit Score: 59.33  E-value: 9.25e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88784158   96 IDNKKLQIIPNPINPGlRPDPNVEMSNIILNVGRLERQKAQDTLIKAF---ANLNPSGW--------------ELHIIGD 158
Cdd:PRK15490 359 LEAKHFQVVYNGVLPP-STEPSSEVPHKIWQQFTQKTQDADTTIGGVFrfvGDKNPFAWidfaarylqhhpatRFVLVGD 437

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88784158  159 GRQRSYLEALIDQLHMNDKVRLLGKKKNIQPYYAKARIFVLSSLYEGFPNVLLEAMQMGKACISTdcPTGPS-DIISHGD 237
Cdd:PRK15490 438 GDLRAEAQKRAEQLGILERILFVGASRDVGYWLQKMNVFILFSRYEGLPNVLIEAQMVGVPVIST--PAGGSaECFIEGV 515

                        170
                 ....*....|....*...
gi 88784158  238 DGILVPVGNTAELEAALR 255
Cdd:PRK15490 516 SGFILDDAQTVNLDQACR 533
PRK15179 PRK15179
Vi polysaccharide biosynthesis protein TviE; Provisional
 127-273 1.65e-09

Vi polysaccharide biosynthesis protein TviE; Provisional


Pssm-ID: 185101 [Multi-domain]  Cd Length: 694  Bit Score: 58.51  E-value: 1.65e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88784158  127 VGRLERQKAQDTLIKA---FANLNPSGwELHIIGDGRQRSYLEALIDQLHMNDKVRLLGKKKNIQPYYAKARIFVLSSLY 203
Cdd:PRK15179 523 VMRVDDNKRPFLWVEAaqrFAASHPKV-RFIMVGGGPLLESVREFAQRLGMGERILFTGLSRRVGYWLTQFNAFLLLSRF 601

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 88784158  204 EGFPNVLLEAMQMGKACISTdCPTGPSDIISHGDDGILVPVGNTA--ELEAALRDLIENPAKERQLGEKAKD 273
Cdd:PRK15179 602 EGLPNVLIEAQFSGVPVVTT-LAGGAGEAVQEGVTGLTLPADTVTapDVAEALARIHDMCAADPGIARKAAD 672
PelF NF038011
GT4 family glycosyltransferase PelF; Proteins of this family are components of the ...
 66-266 1.23e-08

GT4 family glycosyltransferase PelF; Proteins of this family are components of the exopolysaccharide Pel transporter. It has been reported that PelF is a soluble glycosyltransferase that uses UDP-glucose as the substrate for the synthesis of exopolysaccharide Pel, whereas PelG is a Wzx-like and PST family exopolysaccharide transporter.


Pssm-ID: 411604 [Multi-domain]  Cd Length: 489  Bit Score: 55.71  E-value: 1.23e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88784158   66 LW-RF---LKKYTYRKADKLVV--QNNRIKSlyIND-IDNKKLQIIPNPIN-PGLRP-----DPNVemSNIILNVGRLER 132
Cdd:NF038011 242 LWiRFfeaLGRLCYDAADPIVAlyEGNRLRQ--IADgAPPERTRVIPNGIDlPRLAPlraqrPAGI--PPVVGLIGRVVP 317

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88784158  133 QKAQDTLIKAF---ANLNP--SGWelhIIG-DGRQRSYLE---ALIDQLHMNDKVRLLGKKKnIQPYYAKARIFVLSSLY 203
Cdd:NF038011 318 IKDIKTFIRAMrtvVRAMPeaEGW---IVGpEEEDPAYAAecrSLVASLGLQDKVKFLGFQK-IDDLLPQVGLMVLSSIS 393

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 88784158  204 EGFPNVLLEAMQMGKACISTD---CptgpSDIISHGDD--------GILVPVGNTAELEAALRDLIENPAKERQ 266
Cdd:NF038011 394 EALPLVVLEAFAAGVPVVTTDvgsC----RQLIEGLDEedralgaaGEVVAIADPQALARAALDLLRDPQRWQA 463
PLN02871 PLN02871
UDP-sulfoquinovose:DAG sulfoquinovosyltransferase
 123-278 1.31e-07

UDP-sulfoquinovose:DAG sulfoquinovosyltransferase


Pssm-ID: 215469 [Multi-domain]  Cd Length: 465  Bit Score: 52.41  E-value: 1.31e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88784158  123 IILNVGRLERQKAQDTLIKAFANLnpSGWELHIIGDGRQRSYLEALID--------QLHMNDkvrllgkkknIQPYYAKA 194
Cdd:PLN02871 265 LIVYVGRLGAEKNLDFLKRVMERL--PGARLAFVGDGPYREELEKMFAgtptvftgMLQGDE----------LSQAYASG 332

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88784158  195 RIFVLSSLYEGFPNVLLEAMQMGKACISTDCpTGPSDII---SHGDDGILVPVGNTAELEAALRDLIENPAKERQLGEKA 271
Cdd:PLN02871 333 DVFVMPSESETLGFVVLEAMASGVPVVAARA-GGIPDIIppdQEGKTGFLYTPGDVDDCVEKLETLLADPELRERMGAAA 411


                 ....*..
gi 88784158  272 KDATRPY 278
Cdd:PLN02871 412 REEVEKW 418
Glyco_trans_1_2 pfam13524
Glycosyl transferases group 1;
196-276 3.53e-07

Glycosyl transferases group 1;


Pssm-ID: 433281 [Multi-domain]  Cd Length: 93  Bit Score: 47.21  E-value: 3.53e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88784158   196 IFVLSSLYEGFPNV-LLEAMQMGkACISTDCPTGPSDIISHGDDGILVPvgNTAELEAALRDLIENPAKERQLGEKAKDA 274
Cdd:pfam13524   1 IVLNPSRRPDSPNMrVFEAAACG-APLLTDRTPGLEELFEPGEEILLYR--DPEELAEKIRYLLEHPEERRAIAAAGRER 77


                  ..
gi 88784158   275 TR 276
Cdd:pfam13524  78 VL 79
GT4_ExpC-like cd03818
Rhizobium meliloti ExpC and similar proteins; This family is most closely related to the GT4 ...
 78-273 4.19e-07

Rhizobium meliloti ExpC and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. ExpC in Rhizobium meliloti has been shown to be involved in the biosynthesis of galactoglucan (exopolysaccharide II).


Pssm-ID: 340845 [Multi-domain]  Cd Length: 396  Bit Score: 50.82  E-value: 4.19e-07
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88784158  78 ADKLVVQNNRIKSLYINDIDNKkLQIIPNPIN-PGLRPDPNVEM-----------SNIILNVGR-LERQKAQDTLIKAFA 144
Cdd:cd03818 159 ADLGVTPTRWQRSLFPAAYRDR-ISVIHDGVDtDRLAPDPAARLrllngtelkagDPVITYVARnLEPYRGFHVFMRALP 237

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88784158 145 NLNPSGWELHII---GDG--------RQRSYLEALIDQLHMNDK-VRLLGKKkniqPYYAKARIFVLSS--LYEGFPNV- 209
Cdd:cd03818 238 RIQARRPDARVVvvgGDGvsygspppDGGSWKQKMLAELGVDLErVHFVGKV----PYDQYVRLLQLSDahVYLTYPFVl 313

                       170       180       190       200       210       220
                ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 88784158 210 ---LLEAMQMGKACISTDcpTGPSD-IISHGDDGILVPVGNTAELEAALRDLIENPAKERQLGEKAKD 273
Cdd:cd03818 314 swsLLEAMACGCPVIGSD--TAPVReVIRDGRNGLLVDFFDPDALAAAVLELLEDPDRAAALRRAARR 379
GT4_ALG2-like cd03805
alpha-1,3/1,6-mannosyltransferase ALG2 and similar proteins; This family is most closely ...
 69-273 4.44e-07

alpha-1,3/1,6-mannosyltransferase ALG2 and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. ALG2, a 1,3-mannosyltransferase, in yeast catalyzes the mannosylation of Man(2)GlcNAc(2)-dolichol diphosphate and Man(1)GlcNAc(2)-dolichol diphosphate to form Man(3)GlcNAc(2)-dolichol diphosphate. A deficiency of this enzyme causes an abnormal accumulation of Man1GlcNAc2-PP-dolichol and Man2GlcNAc2-PP-dolichol, which is associated with a type of congenital disorders of glycosylation (CDG), designated CDG-Ii, in humans.


Pssm-ID: 340834 [Multi-domain]  Cd Length: 392  Bit Score: 50.67  E-value: 4.44e-07
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88784158  69 FLKKYTYRKADKLVVQNNRIKSLYIN---DIDNKKLQIIPNPIN----PGLRPDPNVEM------SNIILNVGRLERQKA 135
Cdd:cd03805 146 WLEEFTTGMADQIVVNSNFTAGVFKKtfpSLAKNPPEVLYPCVDtdsfDSTSEDPDPGDliaksnKKFFLSINRFERKKN 225

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88784158 136 QDTLIKAFANLNPSGWE-----LHIIG--DGRQ---RSYLEALID----QLHMNDKVRLLgkkKNIQpyyAKARIFVLSS 201
Cdd:cd03805 226 IALAIEAFAKLKQKLPEfenvrLVIAGgyDPRVaenVEYLEELQRlaeeLLNVEDQVLFL---RSIS---DSQKEQLLSS 299

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88784158 202 ----LY----EGFPNVLLEAMQMGKACISTDcPTGPSDIISHGDDGILVPvgNTAELEA-ALRDLIENPAKERQLGEKAK 272
Cdd:cd03805 300 alalLYtpsnEHFGIVPLEAMYAGKPVIACN-SGGPLETVVEGVTGFLCE--PTPEAFAeAMLKLANDPDLADRMGAAGR 376


                .
gi 88784158 273 D 273
Cdd:cd03805 377 K 377
GT4_trehalose_phosphorylase cd03792
trehalose phosphorylase and similar proteins; Trehalose phosphorylase (TP) reversibly ...
 66-272 5.42e-07

trehalose phosphorylase and similar proteins; Trehalose phosphorylase (TP) reversibly catalyzes trehalose synthesis and degradation from alpha-glucose-1-phosphate (alpha-Glc-1-P) and glucose. The catalyzing activity includes the phosphorolysis of trehalose, which produce alpha-Glc-1-P and glucose, and the subsequent synthesis of trehalose. This family is most closely related to the GT4 family of glycosyltransferases.


Pssm-ID: 340823 [Multi-domain]  Cd Length: 378  Bit Score: 50.40  E-value: 5.42e-07
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88784158  66 LWRFLKKYTyRKADKLVVQnnrIKSLYINDIDNKKLqIIPNPINP--GLrpdpNVEMSN------------------IIL 125
Cdd:cd03792 131 VWDFLWNYI-EGYDLFVFH---PPEFVPPQVPPPKF-YIPPSIDPlsGK----NKDLSPadiryylekpfvidperpYIL 201

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88784158 126 NVGRLERQKAQDTLIKAFANL--NPSGWELHIIGDGR------QRSYLEAL-IDQLHMNDKV-RLLGKKKNIQPYYAKAR 195
Cdd:cd03792 202 QVARFDPSKDPLGVIDAYKLFkrRAEEPQLVICGHGAvddpegSVVYEEVMeYAGDDHDIHVlRLPPSDQEINALQRAAT 281

                       170       180       190       200       210       220       230
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 88784158 196 IFVLSSLYEGFPNVLLEAMQMGKACIStdCPTG--PSDIIsHGDDGILVPVGNTAELEaaLRDLIENPAKERQLGEKAK 272
Cdd:cd03792 282 VVLQLSTREGFGLTVSEALWKGKPVIA--TPAGgiPLQVI-DGETGFLVNSVEGAAVR--ILRLLTDPELRRKMGLAAR 355
GT4_PIG-A-like cd03796
phosphatidylinositol N-acetylglucosaminyltransferase subunit A and similar proteins; This ...
 96-224 9.79e-07

phosphatidylinositol N-acetylglucosaminyltransferase subunit A and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. Phosphatidylinositol glycan-class A (PIG-A), an X-linked gene in humans, is necessary for the synthesis of N-acetylglucosaminyl-phosphatidylinositol, a very early intermediate in glycosyl phosphatidylinositol (GPI)-anchor biosynthesis. The GPI-anchor is an important cellular structure that facilitates the attachment of many proteins to cell surfaces. Somatic mutations in PIG-A have been associated with Paroxysmal Nocturnal Hemoglobinuria (PNH), an acquired hematological disorder.


Pssm-ID: 340827 [Multi-domain]  Cd Length: 398  Bit Score: 49.54  E-value: 9.79e-07
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88784158  96 IDNKKLQIIPNPINPG-LRPDPNVEMSNIILNV--GRLERQKAQDTLIKAFANLNPSGWELHII--GDGRQRSYLEALID 170
Cdd:cd03796 165 LDPRIVSVIPNAVDSSdFTPDPSKPDPNKITIVviSRLVYRKGIDLLVGIIPRICKKHPNVRFIigGDGPKRIELEEMRE 244

                        90       100       110       120       130
                ....*....|....*....|....*....|....*....|....*....|....*.
gi 88784158 171 QLHMNDKVRLLG--KKKNIQPYYAKARIFVLSSLYEGFPNVLLEAMQMGKACISTD 224
Cdd:cd03796 245 KYQLQDRVELLGavPHEEVRDVLVQGHIFLNTSLTEAFCIAIVEAASCGLLVVSTR 300
Glyco_transf_4 pfam13439
Glycosyltransferase Family 4;
3-110 1.69e-06

Glycosyltransferase Family 4;


Pssm-ID: 463877 [Multi-domain]  Cd Length: 169  Bit Score: 47.14  E-value: 1.69e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88784158     3 SIRNNWRLYKRVNTLIRENRIELCIGFMTTSNVLSVLASRSN-GIPVVIS------ERNNPEEEKNKLSHLWRFLKKYTY 75
Cdd:pfam13439  52 RLLRSLAFLRRLRRLLRRERPDVVHAHSPFPLGLAALAARLRlGIPLVVTyhglfpDYKRLGARLSPLRRLLRRLERRLL 131

                          90       100       110
                  ....*....|....*....|....*....|....*..
gi 88784158    76 RKADKLVVQNNRIKSLYIND--IDNKKLQIIPNPINP 110
Cdd:pfam13439 132 RRADRVIAVSEAVADELRRLygVPPEKIRVIPNGVDL 168
GT4_WbaZ-like cd03804
mannosyltransferase WbaZ and similar proteins; This family is most closely related to the GT4 ...
 125-261 2.01e-06

mannosyltransferase WbaZ and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. WbaZ in Salmonella enterica has been shown to possess mannosyltransferase activity.


Pssm-ID: 340833 [Multi-domain]  Cd Length: 356  Bit Score: 48.44  E-value: 2.01e-06
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88784158 125 LNVGRLERQKAQDTLIKAFANLnpsGWELHIIGDGRQRSYLEALIDqlhmnDKVRLLGKKKN--IQPYYAKARIFVLSSl 202
Cdd:cd03804 203 LTASRLVPYKRIDLAVEAFNEL---PKRLVVIGDGPDLDRLRAMAS-----PNVEFLGYQPDevLKELLSKARAFVFAA- 273

                        90       100       110       120       130
                ....*....|....*....|....*....|....*....|....*....|....*....
gi 88784158 203 YEGFPNVLLEAMQMGKACISTDcPTGPSDIISHGDDGILVPVGNTAELEAALRDLIENP 261
Cdd:cd03804 274 EEDFGIVPVEAQACGTPVIAFG-KGGALETVRPGPTGILFGEQTVESLKAAVEEFEQNF 331
Glyco_trans_4_4 pfam13579
Glycosyl transferase 4-like domain;
2-107 3.20e-06

Glycosyl transferase 4-like domain;


Pssm-ID: 433325 [Multi-domain]  Cd Length: 158  Bit Score: 46.24  E-value: 3.20e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88784158     2 ESIRNNWRLYKRVNTLIRENRIELCIGFMTTSNVLSVLASRSNGIPVVISERNNPEEEKNKLSH-LWRFLKKYTYRKADK 80
Cdd:pfam13579  51 PSPLADLAALRRLRRLLRAERPDVVHAHSPTAGLAARLARRRRGVPLVVTVHGLALDYGSGWKRrLARALERRLLRRADA 130

                          90       100
                  ....*....|....*....|....*...
gi 88784158    81 LVVQNNRIKSLYIN-DIDNKKLQIIPNP 107
Cdd:pfam13579 131 VVVVSEAEAELLRAlGVPAARVVVVPNG 158
GT4_mannosyltransferase-like cd03822
mannosyltransferases of glycosyltransferase family 4 and similar proteins; This family is most ...
 93-284 3.62e-06

mannosyltransferases of glycosyltransferase family 4 and similar proteins; This family is most closely related to the GT1 family of glycosyltransferases. ORF704 in E. coli has been shown to be involved in the biosynthesis of O-specific mannose homopolysaccharides.


Pssm-ID: 340849 [Multi-domain]  Cd Length: 370  Bit Score: 47.76  E-value: 3.62e-06
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88784158  93 INDIDNKKLQIIPNPIN-------PGLRPDPNVEMSNIILNVGRLERQKAQDTLIKAFANLNPSGWELH--IIG------ 157
Cdd:cd03822 152 IKLIPAVNIEVIPHGVPevpqdptTALKRLLLPEGKKVILTFGFIGPGKGLEILLEALPELKAEFPDVRlvIAGelhpsl 231

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88784158 158 -DGRQRSYLEALIDQLHMNDKVRLLGKK--KNIQPYYAKAR-IFVLSSLYEGFPN--VLLEAMQMGKACISTdcPTGPSD 231
Cdd:cd03822 232 aRYEGERYRKAAIEELGLQDHVDFHNNFlpEEEVPRYISAAdVVVLPYLNTEQSSsgTLSYAIACGKPVIST--PLRHAE 309

                       170       180       190       200       210
                ....*....|....*....|....*....|....*....|....*....|...
gi 88784158 232 IISHGDDGILVPVGNTAELEAALRDLIENPAKERQLGEKAKDATRPYQIENIA 284
Cdd:cd03822 310 ELLADGRGVLVPFDDPSAIAEAILRLLEDDERRQAIAERAYAYARAMTWESIA 362
GT4_AmsK-like cd04946
amylovoran biosynthesis glycosyltransferase AmsK and similar proteins; This family is most ...
 156-272 2.42e-05

amylovoran biosynthesis glycosyltransferase AmsK and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. AmsK is involved in the biosynthesis of amylovoran, which functions as a virulence factor. It functions as a glycosyl transferase which transfers galactose from UDP-galactose to a lipid-linked amylovoran-subunit precursor. The members of this family are found mainly in bacteria and Archaea.


Pssm-ID: 340854 [Multi-domain]  Cd Length: 401  Bit Score: 45.14  E-value: 2.42e-05
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88784158 156 IGDGRQRSYLEALIDQLHMNDKVRLLG--KKKNIQPYYAK--ARIFVLSSLYEGFPNVLLEAMQMGKACISTDCpTGPSD 231
Cdd:cd04946 263 IGGGPLKERLEKLAENKLENVKVNFTGevSNKEVKQLYKEndVDVFVNVSESEGIPVSIMEAISFGIPVIATNV-GGTRE 341

                        90       100       110       120
                ....*....|....*....|....*....|....*....|...
gi 88784158 232 IISHGDDGILvPVGNTA--ELEAALRDLIENPAKERQLGEKAK 272
Cdd:cd04946 342 IVENETNGLL-LDKDPTpnEIVSSIMKFYLDGGDYKTMKISAR 383
GT4_AviGT4-like cd03802
UDP-Glc:tetrahydrobiopterin alpha-glucosyltransferase and similar proteins; This family is ...
 103-257 1.19e-04

UDP-Glc:tetrahydrobiopterin alpha-glucosyltransferase and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. aviGT4 in Streptomyces viridochromogenes has been shown to be involved in biosynthesis of oligosaccharide antibiotic avilamycin A. Inactivation of aviGT4 resulted in a mutant that accumulated a novel avilamycin derivative lacking the terminal eurekanate residue.


Pssm-ID: 340832 [Multi-domain]  Cd Length: 333  Bit Score: 43.05  E-value: 1.19e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88784158 103 IIPNPINPGL-RPDPNVEmsNIILNVGRLERQKAQDTLIKAFANlnpSGWELHIIGDGRQRSYLEALIdQLHMNDKVRLL 181
Cdd:cd03802 152 VVHNGLDPADyRFQPDPE--DYLAFLGRIAPEKGLEDAIRVARR---AGLPLKIAGKVRDEDYFYYLQ-EPLPGPRIEFI 225

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88784158 182 G------KKKNIQPyyAKARIFvLSSLYEGFPNVLLEAMQMGKACISTDCpTGPSDIISHGDDGILVPvgNTAELEAALR 255
Cdd:cd03802 226 GevghdeKQELLGG--ARALLF-PINWDEPFGLVMIEAMACGTPVIAYRR-GGLPEVIQHGETGFLVD--SVEEMAEAIA 299


                ..
gi 88784158 256 DL 257
Cdd:cd03802 300 NI 301
MSMEG_0565_glyc TIGR04047
glycosyltransferase, MSMEG_0565 family; A conserved gene cluster found sporadically from ...
 119-278 1.89e-03

glycosyltransferase, MSMEG_0565 family; A conserved gene cluster found sporadically from Actinobacteria to Proteobacteria to Cyanobacteria features a radical SAM protein, an N-acetyltransferase, an oxidoreductase, and two additional proteins whose functional classes are unclear. The metabolic role of the cluster is probably biosynthetic. This glycosyltransferase, named from member MSMEG_0565 from Mycobacterium smegmatis, occurs in most but not all instances of the cluster. [Unknown function, Enzymes of unknown specificity]


Pssm-ID: 274943 [Multi-domain]  Cd Length: 373  Bit Score: 39.30  E-value: 1.89e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88784158   119 EMSNIILNVGRLERQKAQDTLIKAFANLNPSGWELH-IIGDGRQ----RSYLEALIDQLHMND----KVRLLG--KKKNI 187
Cdd:TIGR04047 191 RGGPYVLAVGGIEPRKNTIDLLEAFALLRARRPQAQlVIAGGATlfdyDAYRREFRARAAELGvdpgPVVITGpvPDADL 270

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88784158   188 QPYYAKARIFVLSSLYEGFPNVLLEAMQMGKACISTDCPtgPSDIISHGDDGILVPVGNTAELEAALRDLIEnPAKERQL 267
Cdd:TIGR04047 271 PALYRCADAFAFPSLKEGFGLVVLEALASGIPVVASDIA--PFTEYLGRFDAAWADPSDPDSIADALALALD-PARRPAL 347

                         170
                  ....*....|.
gi 88784158   268 GEKAKDATRPY 278
Cdd:TIGR04047 348 RAAGPELAARY 358
PRK15484 PRK15484
lipopolysaccharide N-acetylglucosaminyltransferase;
80-219 3.56e-03

lipopolysaccharide N-acetylglucosaminyltransferase;


Pssm-ID: 185381 [Multi-domain]  Cd Length: 380  Bit Score: 38.62  E-value: 3.56e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88784158   80 KLVVQNNRIKSLYINDIDNKKLQIIPNPI---------NPGLRPDPNV-EMSNIILNVGRLERQKAQDTLIKAFANLNP- 148
Cdd:PRK15484 142 KIIVPSQFLKKFYEERLPNADISIVPNGFcletyqsnpQPNLRQQLNIsPDETVLLYAGRISPDKGILLLMQAFEKLATa 221

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 88784158  149 -SGWELHIIGD------GRQRSY-------LEALIDQLHMndkvrlLGKK--KNIQPYYAKARIFVL-SSLYEGFPNVLL 211
Cdd:PRK15484 222 hSNLKLVVVGDptasskGEKAAYqkkvleaAKRIGDRCIM------LGGQppEKMHNYYPLADLVVVpSQVEEAFCMVAV 295


                 ....*...
gi 88784158  212 EAMQMGKA 219
Cdd:PRK15484 296 EAMAAGKP 303
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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