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Conserved domains on  [gi|874572287|emb|CRY93171|]
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pyridine nucleotide-disulfide oxidoreductase family protein [Synechococcus sp. WH 8103]

Protein Classification

NAD(P)/FAD-dependent oxidoreductase( domain architecture ID 11441299)

NAD(P)/FAD-dependent oxidoreductase catalyzes the transfer of electrons from one molecule, the electron donor or reductant, to another molecule, the electron acceptor or oxidant; similar to sulfide:quinone oxidoreductase which catalyzes the oxidation of hydrogen sulfide using quinone as the electron acceptor

EC:  1.6.-.-
Gene Ontology:  GO:0003954|GO:0006116
PubMed:  15590775|28181562

Graphical summary

 Zoom to residue level

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List of domain hits

 Name Accession Description Interval E-value
Ndh COG1252
NADH dehydrogenase, FAD-containing subunit [Energy production and conversion];
2-358 3.15e-94

NADH dehydrogenase, FAD-containing subunit [Energy production and conversion];


:

Pssm-ID: 440864 [Multi-domain]  Cd Length: 386  Bit Score: 286.64  E-value: 3.15e-94
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 874572287   2 VVIGGGFAGLFSALAVSERLPERP-VLLIEPRDRFLFQPLLYELLSSELQGWEVAPTYRQLLSSRGICWLQDRVINIDLN 80
Cdd:COG1252    5 VIVGGGFAGLEAARRLRKKLGGDAeVTLIDPNPYHLFQPLLPEVAAGTLSPDDIAIPLRELLRRAGVRFIQGEVTGIDPE 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 874572287  81 NQELTTAASGALQWGDLVLATGTELNDFGVPGVREHACSFRDLNDVAHLRALVRELNKRREPDAA--VAIIGAGPTGVEL 158
Cdd:COG1252   85 ARTVTLADGRTLSYDYLVIATGSVTNFFGIPGLAEHALPLKTLEDALALRERLLAAFERAERRRLltIVVVGGGPTGVEL 164

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 874572287 159 ACKLADMLDGA----------ARIHLIERGDGILPNSASFNRERAAAALERRDVCLHLNTAVTEVHSDRVRFKDGTLLPH 228
Cdd:COG1252  165 AGELAELLRKLlrypgidpdkVRITLVEAGPRILPGLGEKLSEAAEKELEKRGVEVHTGTRVTEVDADGVTLEDGEEIPA 244

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 874572287 229 SGLIWSAGSR-PTVPDIRPDPGHAKGPLNIGQDLRLLGHQHVYVLGDCGRC---SVEPWPATAQVAMQQGEAVAAALQAI 304
Cdd:COG1252  245 DTVIWAAGVKaPPLLADLGLPTDRRGRVLVDPTLQVPGHPNVFAIGDCAAVpdpDGKPVPKTAQAAVQQAKVLAKNIAAL 324

                        330       340       350       360       370
                 ....*....|....*....|....*....|....*....|....*....|....
gi 874572287 305 SNNQEPKPFQFQDRGEMLSLGIGDATLTGLGITLAGPLAFKIRRATYLTRLPGL 358
Cdd:COG1252  325 LRGKPLKPFRYRDKGCLASLGRGAAVADVGGLKLSGFLAWLLKRAIHLYFLPGF 378
 
Name Accession Description Interval E-value
Ndh COG1252
NADH dehydrogenase, FAD-containing subunit [Energy production and conversion];
2-358 3.15e-94

NADH dehydrogenase, FAD-containing subunit [Energy production and conversion];


Pssm-ID: 440864 [Multi-domain]  Cd Length: 386  Bit Score: 286.64  E-value: 3.15e-94
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 874572287   2 VVIGGGFAGLFSALAVSERLPERP-VLLIEPRDRFLFQPLLYELLSSELQGWEVAPTYRQLLSSRGICWLQDRVINIDLN 80
Cdd:COG1252    5 VIVGGGFAGLEAARRLRKKLGGDAeVTLIDPNPYHLFQPLLPEVAAGTLSPDDIAIPLRELLRRAGVRFIQGEVTGIDPE 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 874572287  81 NQELTTAASGALQWGDLVLATGTELNDFGVPGVREHACSFRDLNDVAHLRALVRELNKRREPDAA--VAIIGAGPTGVEL 158
Cdd:COG1252   85 ARTVTLADGRTLSYDYLVIATGSVTNFFGIPGLAEHALPLKTLEDALALRERLLAAFERAERRRLltIVVVGGGPTGVEL 164

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 874572287 159 ACKLADMLDGA----------ARIHLIERGDGILPNSASFNRERAAAALERRDVCLHLNTAVTEVHSDRVRFKDGTLLPH 228
Cdd:COG1252  165 AGELAELLRKLlrypgidpdkVRITLVEAGPRILPGLGEKLSEAAEKELEKRGVEVHTGTRVTEVDADGVTLEDGEEIPA 244

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 874572287 229 SGLIWSAGSR-PTVPDIRPDPGHAKGPLNIGQDLRLLGHQHVYVLGDCGRC---SVEPWPATAQVAMQQGEAVAAALQAI 304
Cdd:COG1252  245 DTVIWAAGVKaPPLLADLGLPTDRRGRVLVDPTLQVPGHPNVFAIGDCAAVpdpDGKPVPKTAQAAVQQAKVLAKNIAAL 324

                        330       340       350       360       370
                 ....*....|....*....|....*....|....*....|....*....|....
gi 874572287 305 SNNQEPKPFQFQDRGEMLSLGIGDATLTGLGITLAGPLAFKIRRATYLTRLPGL 358
Cdd:COG1252  325 LRGKPLKPFRYRDKGCLASLGRGAAVADVGGLKLSGFLAWLLKRAIHLYFLPGF 378
PTZ00318 PTZ00318
NADH dehydrogenase-like protein; Provisional
 1-355 4.17e-48

NADH dehydrogenase-like protein; Provisional


Pssm-ID: 185553 [Multi-domain]  Cd Length: 424  Bit Score: 168.02  E-value: 4.17e-48
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 874572287   1 MVVIGGGFAGLFSALAVSERLPErpVLLIEPRDRFLFQPLLYELLSSELQGWEVAPTYRQLLSSRGICWLQDRVINIDLN 80
Cdd:PTZ00318  13 VVVLGTGWAGAYFVRNLDPKKYN--ITVISPRNHMLFTPLLPQTTTGTLEFRSICEPVRPALAKLPNRYLRAVVYDVDFE 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 874572287  81 NQELTTAASG----------ALQWGDLVLATGTELNDFGVPGVREHACSFRDLNDVAHLRA-LVRELNKRREPDAAVA-- 147
Cdd:PTZ00318  91 EKRVKCGVVSksnnanvntfSVPYDKLVVAHGARPNTFNIPGVEERAFFLKEVNHARGIRKrIVQCIERASLPTTSVEer 170

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 874572287 148 -------IIGAGPTGVELACKLADML-DGAARIH----------LIERGDGILpnsASFN---RERAAAALERRDVCLHL 206
Cdd:PTZ00318 171 krllhfvVVGGGPTGVEFAAELADFFrDDVRNLNpelveeckvtVLEAGSEVL---GSFDqalRKYGQRRLRRLGVDIRT 247

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 874572287 207 NTAVTEVHSDRVRFKDGTLLPHSGLIWSAG--SRPTVPDIRPDPgHAKGPLNIGQDLRLLGHQHVYVLGDCGRCSVEPWP 284
Cdd:PTZ00318 248 KTAVKEVLDKEVVLKDGEVIPTGLVVWSTGvgPGPLTKQLKVDK-TSRGRISVDDHLRVKPIPNVFALGDCAANEERPLP 326

                        330       340       350       360       370       380       390
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 874572287 285 ATAQVAMQQGEAVAAAL-QAISNNQEPKPFQFQDRGEMLSLGIGDATLTGLGITLAGPLAFKIRRATYLTRL 355
Cdd:PTZ00318 327 TLAQVASQQGVYLAKEFnNELKGKPMSKPFVYRSLGSLAYLGNYSAIVQLGAFDLSGFKALLFWRSAYLTIL 398
Pyr_redox_2 pfam07992
Pyridine nucleotide-disulphide oxidoreductase; This family includes both class I and class II ...
 2-294 3.20e-33

Pyridine nucleotide-disulphide oxidoreductase; This family includes both class I and class II oxidoreductases and also NADH oxidases and peroxidases. This domain is actually a small NADH binding domain within a larger FAD binding domain.


Pssm-ID: 400379 [Multi-domain]  Cd Length: 301  Bit Score: 125.51  E-value: 3.20e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 874572287    2 VVIGGGFAGLFSALAVSERlpERPVLLIE-PRDRFLFQPLLYELLSSELQGWEVAPTYRQLLSS---------RGICWLQ 71
Cdd:pfam07992   4 VVIGGGPAGLAAALTLAQL--GGKVTLIEdEGTCPYGGCVLSKALLGAAEAPEIASLWADLYKRkeevvkklnNGIEVLL 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 874572287   72 DR-VINIDLNNQELTTAAS-----GALQWGDLVLATGTELNDFGVPGVREHAC-SFRDLNDVahlRALVRELNKRRepda 144
Cdd:pfam07992  82 GTeVVSIDPGAKKVVLEELvdgdgETITYDRLVIATGARPRLPPIPGVELNVGfLVRTLDSA---EALRLKLLPKR---- 154

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 874572287  145 aVAIIGAGPTGVELACKLADMldgAARIHLIERGDGILPNSASFNRERAAAALERRDVCLHLNTAVTEV----HSDRVRF 220
Cdd:pfam07992 155 -VVVVGGGYIGVELAAALAKL---GKEVTLIEALDRLLRAFDEEISAALEKALEKNGVEVRLGTSVKEIigdgDGVEVIL 230

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 874572287  221 KDGTLLPHSGLIWSAGSRPTVPDIRPDpGHAKGPLN-IGQDLRL-LGHQHVYVLGDCGRcsvePWPATAQVAMQQG 294
Cdd:pfam07992 231 KDGTEIDADLVVVAIGRRPNTELLEAA-GLELDERGgIVVDEYLrTSVPGIYAAGDCRV----GGPELAQNAVAQG 301
nitri_red_nirB TIGR02374
nitrite reductase [NAD(P)H], large subunit; [Central intermediary metabolism, Nitrogen ...
 69-329 4.99e-12

nitrite reductase [NAD(P)H], large subunit; [Central intermediary metabolism, Nitrogen metabolism]


Pssm-ID: 162827 [Multi-domain]  Cd Length: 785  Bit Score: 67.16  E-value: 4.99e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 874572287   69 WLQDRVINIDLNNQELTTAASGALQWGDLVLATGTELNDFGVPGVREHAC-SFRDLNDVAHLRALVrelnkRREPDAAVa 147
Cdd:TIGR02374  72 YTGETVIQIDTDQKQVITDAGRTLSYDKLILATGSYPFILPIPGADKKGVyVFRTIEDLDAIMAMA-----QRFKKAAV- 145

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 874572287  148 iIGAGPTGVELACKLADMldgAARIHLIERGDGILPNSAsfnrERAAAALERRD-----VCLHLNTAVTEV--HS--DRV 218
Cdd:TIGR02374 146 -IGGGLLGLEAAVGLQNL---GMDVSVIHHAPGLMAKQL----DQTAGRLLQREleqkgLTFLLEKDTVEIvgATkaDRI 217

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 874572287  219 RFKDGTLLPHSGLIWSAGSRPtvpdiRPDPGHAKG-PLNIG---QDLRLLGHQHVYVLGDC----GRCS--VEPwpataq 288
Cdd:TIGR02374 218 RFKDGSSLEADLIVMAAGIRP-----NDELAVSAGiKVNRGiivNDSMQTSDPDIYAVGECaehnGRVYglVAP------ 286

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*..
gi 874572287  289 vAMQQGEAVAAALQAIsnnqEPKPFQFQDRGEMLSL------GIGDA 329
Cdd:TIGR02374 287 -LYEQAKVLADHICGV----ECEEYEGSDLSAKLKLlgvdvwSAGDA 328
 
Name Accession Description Interval E-value
Ndh COG1252
NADH dehydrogenase, FAD-containing subunit [Energy production and conversion];
2-358 3.15e-94

NADH dehydrogenase, FAD-containing subunit [Energy production and conversion];


Pssm-ID: 440864 [Multi-domain]  Cd Length: 386  Bit Score: 286.64  E-value: 3.15e-94
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 874572287   2 VVIGGGFAGLFSALAVSERLPERP-VLLIEPRDRFLFQPLLYELLSSELQGWEVAPTYRQLLSSRGICWLQDRVINIDLN 80
Cdd:COG1252    5 VIVGGGFAGLEAARRLRKKLGGDAeVTLIDPNPYHLFQPLLPEVAAGTLSPDDIAIPLRELLRRAGVRFIQGEVTGIDPE 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 874572287  81 NQELTTAASGALQWGDLVLATGTELNDFGVPGVREHACSFRDLNDVAHLRALVRELNKRREPDAA--VAIIGAGPTGVEL 158
Cdd:COG1252   85 ARTVTLADGRTLSYDYLVIATGSVTNFFGIPGLAEHALPLKTLEDALALRERLLAAFERAERRRLltIVVVGGGPTGVEL 164

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 874572287 159 ACKLADMLDGA----------ARIHLIERGDGILPNSASFNRERAAAALERRDVCLHLNTAVTEVHSDRVRFKDGTLLPH 228
Cdd:COG1252  165 AGELAELLRKLlrypgidpdkVRITLVEAGPRILPGLGEKLSEAAEKELEKRGVEVHTGTRVTEVDADGVTLEDGEEIPA 244

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 874572287 229 SGLIWSAGSR-PTVPDIRPDPGHAKGPLNIGQDLRLLGHQHVYVLGDCGRC---SVEPWPATAQVAMQQGEAVAAALQAI 304
Cdd:COG1252  245 DTVIWAAGVKaPPLLADLGLPTDRRGRVLVDPTLQVPGHPNVFAIGDCAAVpdpDGKPVPKTAQAAVQQAKVLAKNIAAL 324

                        330       340       350       360       370
                 ....*....|....*....|....*....|....*....|....*....|....
gi 874572287 305 SNNQEPKPFQFQDRGEMLSLGIGDATLTGLGITLAGPLAFKIRRATYLTRLPGL 358
Cdd:COG1252  325 LRGKPLKPFRYRDKGCLASLGRGAAVADVGGLKLSGFLAWLLKRAIHLYFLPGF 378
PTZ00318 PTZ00318
NADH dehydrogenase-like protein; Provisional
 1-355 4.17e-48

NADH dehydrogenase-like protein; Provisional


Pssm-ID: 185553 [Multi-domain]  Cd Length: 424  Bit Score: 168.02  E-value: 4.17e-48
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 874572287   1 MVVIGGGFAGLFSALAVSERLPErpVLLIEPRDRFLFQPLLYELLSSELQGWEVAPTYRQLLSSRGICWLQDRVINIDLN 80
Cdd:PTZ00318  13 VVVLGTGWAGAYFVRNLDPKKYN--ITVISPRNHMLFTPLLPQTTTGTLEFRSICEPVRPALAKLPNRYLRAVVYDVDFE 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 874572287  81 NQELTTAASG----------ALQWGDLVLATGTELNDFGVPGVREHACSFRDLNDVAHLRA-LVRELNKRREPDAAVA-- 147
Cdd:PTZ00318  91 EKRVKCGVVSksnnanvntfSVPYDKLVVAHGARPNTFNIPGVEERAFFLKEVNHARGIRKrIVQCIERASLPTTSVEer 170

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 874572287 148 -------IIGAGPTGVELACKLADML-DGAARIH----------LIERGDGILpnsASFN---RERAAAALERRDVCLHL 206
Cdd:PTZ00318 171 krllhfvVVGGGPTGVEFAAELADFFrDDVRNLNpelveeckvtVLEAGSEVL---GSFDqalRKYGQRRLRRLGVDIRT 247

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 874572287 207 NTAVTEVHSDRVRFKDGTLLPHSGLIWSAG--SRPTVPDIRPDPgHAKGPLNIGQDLRLLGHQHVYVLGDCGRCSVEPWP 284
Cdd:PTZ00318 248 KTAVKEVLDKEVVLKDGEVIPTGLVVWSTGvgPGPLTKQLKVDK-TSRGRISVDDHLRVKPIPNVFALGDCAANEERPLP 326

                        330       340       350       360       370       380       390
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 874572287 285 ATAQVAMQQGEAVAAAL-QAISNNQEPKPFQFQDRGEMLSLGIGDATLTGLGITLAGPLAFKIRRATYLTRL 355
Cdd:PTZ00318 327 TLAQVASQQGVYLAKEFnNELKGKPMSKPFVYRSLGSLAYLGNYSAIVQLGAFDLSGFKALLFWRSAYLTIL 398
Pyr_redox_2 pfam07992
Pyridine nucleotide-disulphide oxidoreductase; This family includes both class I and class II ...
 2-294 3.20e-33

Pyridine nucleotide-disulphide oxidoreductase; This family includes both class I and class II oxidoreductases and also NADH oxidases and peroxidases. This domain is actually a small NADH binding domain within a larger FAD binding domain.


Pssm-ID: 400379 [Multi-domain]  Cd Length: 301  Bit Score: 125.51  E-value: 3.20e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 874572287    2 VVIGGGFAGLFSALAVSERlpERPVLLIE-PRDRFLFQPLLYELLSSELQGWEVAPTYRQLLSS---------RGICWLQ 71
Cdd:pfam07992   4 VVIGGGPAGLAAALTLAQL--GGKVTLIEdEGTCPYGGCVLSKALLGAAEAPEIASLWADLYKRkeevvkklnNGIEVLL 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 874572287   72 DR-VINIDLNNQELTTAAS-----GALQWGDLVLATGTELNDFGVPGVREHAC-SFRDLNDVahlRALVRELNKRRepda 144
Cdd:pfam07992  82 GTeVVSIDPGAKKVVLEELvdgdgETITYDRLVIATGARPRLPPIPGVELNVGfLVRTLDSA---EALRLKLLPKR---- 154

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 874572287  145 aVAIIGAGPTGVELACKLADMldgAARIHLIERGDGILPNSASFNRERAAAALERRDVCLHLNTAVTEV----HSDRVRF 220
Cdd:pfam07992 155 -VVVVGGGYIGVELAAALAKL---GKEVTLIEALDRLLRAFDEEISAALEKALEKNGVEVRLGTSVKEIigdgDGVEVIL 230

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 874572287  221 KDGTLLPHSGLIWSAGSRPTVPDIRPDpGHAKGPLN-IGQDLRL-LGHQHVYVLGDCGRcsvePWPATAQVAMQQG 294
Cdd:pfam07992 231 KDGTEIDADLVVVAIGRRPNTELLEAA-GLELDERGgIVVDEYLrTSVPGIYAAGDCRV----GGPELAQNAVAQG 301
NirB COG1251
NAD(P)H-nitrite reductase, large subunit [Energy production and conversion];
2-301 1.14e-28

NAD(P)H-nitrite reductase, large subunit [Energy production and conversion];


Pssm-ID: 440863 [Multi-domain]  Cd Length: 402  Bit Score: 115.24  E-value: 1.14e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 874572287   2 VVIGGGFAGLFSALAVSERLPERPVLLI--EPR---DR-----FLFQPLLYELLSSELQGWevaptYRQLlssrGI-CWL 70
Cdd:COG1251    5 VIIGAGMAGVRAAEELRKLDPDGEITVIgaEPHppyNRpplskVLAGETDEEDLLLRPADF-----YEEN----GIdLRL 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 874572287  71 QDRVINIDLNNQELTTAASGALQWGDLVLATGTELNDFGVPGV-REHACSFRDLNDVAHLRALVRelNKRRepdaaVAII 149
Cdd:COG1251   76 GTRVTAIDRAARTVTLADGETLPYDKLVLATGSRPRVPPIPGAdLPGVFTLRTLDDADALRAALA--PGKR-----VVVI 148

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 874572287 150 GAGPTGVELAcklADMLDGAARIHLIERGDGILPNSASfnrERAAA----ALERRDVCLHLNTAVTEVHSD----RVRFK 221
Cdd:COG1251  149 GGGLIGLEAA---AALRKRGLEVTVVERAPRLLPRQLD---EEAGAllqrLLEALGVEVRLGTGVTEIEGDdrvtGVRLA 222

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 874572287 222 DGTLLPHSGLIWSAGsrptvpdIRPDPGHAKG-PLNIGQ----DLRLL-GHQHVYVLGDC----GRCSVEPWPATAQVAM 291
Cdd:COG1251  223 DGEELPADLVVVAIG-------VRPNTELARAaGLAVDRgivvDDYLRtSDPDIYAAGDCaehpGPVYGRRVLELVAPAY 295

                        330
                 ....*....|
gi 874572287 292 QQGEAVAAAL 301
Cdd:COG1251  296 EQARVAAANL 305
FadH2 COG0446
NADPH-dependent 2,4-dienoyl-CoA reductase, sulfur reductase, or a related oxidoreductase ...
 19-301 3.63e-27

NADPH-dependent 2,4-dienoyl-CoA reductase, sulfur reductase, or a related oxidoreductase [Lipid transport and metabolism];


Pssm-ID: 440215 [Multi-domain]  Cd Length: 322  Bit Score: 109.52  E-value: 3.63e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 874572287  19 ERLPERPVLLIEPRDRFLFQPLLyellsselqGW----EVAPTYRQLLSS-------RGICW-LQDRVINIDLNNQELTT 86
Cdd:COG0446    1 RLGPDAEITVIEKGPHHSYQPCG---------LPyyvgGGIKDPEDLLVRtpesferKGIDVrTGTEVTAIDPEAKTVTL 71

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 874572287  87 AASGALQWGDLVLATGTELNDFGVPGVR-EHACSFRDLNDVAHLRALVRELNKRRepdaaVAIIGAGPTGVELACKLADM 165
Cdd:COG0446   72 RDGETLSYDKLVLATGARPRPPPIPGLDlPGVFTLRTLDDADALREALKEFKGKR-----AVVIGGGPIGLELAEALRKR 146

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 874572287 166 ldGaARIHLIERGDGILPNSASFNRERAAAALERRDVCLHLNTAVTEVHSD---RVRFKDGTLLPHSGLIWSAGSRPTVp 242
Cdd:COG0446  147 --G-LKVTLVERAPRLLGVLDPEMAALLEEELREHGVELRLGETVVAIDGDdkvAVTLTDGEEIPADLVVVAPGVRPNT- 222

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 874572287 243 DIRPDPGHAKGPLN---IGQDLRlLGHQHVYVLGDCGRC-----SVEPWPATAQVAMQQGEAVAAAL 301
Cdd:COG0446  223 ELAKDAGLALGERGwikVDETLQ-TSDPDVYAAGDCAEVphpvtGKTVYIPLASAANKQGRVAAENI 288
Lpd COG1249
Dihydrolipoamide dehydrogenase (E3) component of pyruvate/2-oxoglutarate dehydrogenase complex ...
 98-301 1.87e-13

Dihydrolipoamide dehydrogenase (E3) component of pyruvate/2-oxoglutarate dehydrogenase complex or glutathione oxidoreductase [Energy production and conversion]; Dihydrolipoamide dehydrogenase (E3) component of pyruvate/2-oxoglutarate dehydrogenase complex or glutathione oxidoreductase is part of the Pathway/BioSystem: Glycine cleavagePyruvate oxidation


Pssm-ID: 440861 [Multi-domain]  Cd Length: 456  Bit Score: 71.27  E-value: 1.87e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 874572287  98 VLATGTE---LNDFGVPGVRehacsFRDLNDVAHLRALVRELnkrrepdaavAIIGAGPTGVELACKLADMldGaARIHL 174
Cdd:COG1249  135 VIATGSRprvPPIPGLDEVR-----VLTSDEALELEELPKSL----------VVIGGGYIGLEFAQIFARL--G-SEVTL 196

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 874572287 175 IERGDGILPNSASFNRERAAAALERRDVCLHLNTAVTEVHSD----RVRFKDGTLLPHSG---LIWSAGSRPTVPD---- 243
Cdd:COG1249  197 VERGDRLLPGEDPEISEALEKALEKEGIDILTGAKVTSVEKTgdgvTVTLEDGGGEEAVEadkVLVATGRRPNTDGlgle 276

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 874572287 244 ---IRPDPghaKGPLNIGQDLRlLGHQHVYVLGDC-GRcsvepwPATAQVAMQQGEAVAAAL 301
Cdd:COG1249  277 aagVELDE---RGGIKVDEYLR-TSVPGIYAIGDVtGG------PQLAHVASAEGRVAAENI 328
nitri_red_nirB TIGR02374
nitrite reductase [NAD(P)H], large subunit; [Central intermediary metabolism, Nitrogen ...
 69-329 4.99e-12

nitrite reductase [NAD(P)H], large subunit; [Central intermediary metabolism, Nitrogen metabolism]


Pssm-ID: 162827 [Multi-domain]  Cd Length: 785  Bit Score: 67.16  E-value: 4.99e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 874572287   69 WLQDRVINIDLNNQELTTAASGALQWGDLVLATGTELNDFGVPGVREHAC-SFRDLNDVAHLRALVrelnkRREPDAAVa 147
Cdd:TIGR02374  72 YTGETVIQIDTDQKQVITDAGRTLSYDKLILATGSYPFILPIPGADKKGVyVFRTIEDLDAIMAMA-----QRFKKAAV- 145

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 874572287  148 iIGAGPTGVELACKLADMldgAARIHLIERGDGILPNSAsfnrERAAAALERRD-----VCLHLNTAVTEV--HS--DRV 218
Cdd:TIGR02374 146 -IGGGLLGLEAAVGLQNL---GMDVSVIHHAPGLMAKQL----DQTAGRLLQREleqkgLTFLLEKDTVEIvgATkaDRI 217

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 874572287  219 RFKDGTLLPHSGLIWSAGSRPtvpdiRPDPGHAKG-PLNIG---QDLRLLGHQHVYVLGDC----GRCS--VEPwpataq 288
Cdd:TIGR02374 218 RFKDGSSLEADLIVMAAGIRP-----NDELAVSAGiKVNRGiivNDSMQTSDPDIYAVGECaehnGRVYglVAP------ 286

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*..
gi 874572287  289 vAMQQGEAVAAALQAIsnnqEPKPFQFQDRGEMLSL------GIGDA 329
Cdd:TIGR02374 287 -LYEQAKVLADHICGV----ECEEYEGSDLSAKLKLlgvdvwSAGDA 328
Pyr_redox pfam00070
Pyridine nucleotide-disulphide oxidoreductase; This family includes both class I and class II ...
 146-223 4.96e-10

Pyridine nucleotide-disulphide oxidoreductase; This family includes both class I and class II oxidoreductases and also NADH oxidases and peroxidases. This domain is actually a small NADH binding domain within a larger FAD binding domain.


Pssm-ID: 425450 [Multi-domain]  Cd Length: 80  Bit Score: 55.29  E-value: 4.96e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 874572287  146 VAIIGAGPTGVELACKLADMldgAARIHLIERGDGILPNSASFNRERAAAALERRDVCLHLNTAVTEVHSD----RVRFK 221
Cdd:pfam00070   2 VVVVGGGYIGLELAGALARL---GSKVTVVERRDRLLPGFDPEIAKILQEKLEKNGIEFLLNTTVEAIEGNgdgvVVVLT 78


                  ..
gi 874572287  222 DG 223
Cdd:pfam00070  79 DG 80
TrxB COG0492
Thioredoxin reductase [Posttranslational modification, protein turnover, chaperones];
2-239 1.18e-08

Thioredoxin reductase [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440258 [Multi-domain]  Cd Length: 305  Bit Score: 55.90  E-value: 1.18e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 874572287   2 VVIGGGFAGLFSAL-AVSERLPerpVLLIEpRDRFLFQPLLYEL------LSSELQGWEVAPTYRQLLSSRGICWLQDRV 74
Cdd:COG0492    4 VIIGAGPAGLTAAIyAARAGLK---TLVIE-GGEPGGQLATTKEienypgFPEGISGPELAERLREQAERFGAEILLEEV 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 874572287  75 INIDLNNQ--ELTTAASGALQWGDLVLATGTELNDFGVPGVRE------HACSFRDlndvahlRALVRelNKRrepdaaV 146
Cdd:COG0492   80 TSVDKDDGpfRVTTDDGTEYEAKAVIIATGAGPRKLGLPGEEEfegrgvSYCATCD-------GFFFR--GKD------V 144

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 874572287 147 AIIGAGPTGVELACKLADMldgAARIHLIERGDGIlpnsasfnreRAAAALERR-----DVCLHLNTAVTEVHSD----R 217
Cdd:COG0492  145 VVVGGGDSALEEALYLTKF---ASKVTLIHRRDEL----------RASKILVERlranpKIEVLWNTEVTEIEGDgrveG 211

                        250       260
                 ....*....|....*....|....*..
gi 874572287 218 VRFKDG-----TLLPHSGLIWSAGSRP 239
Cdd:COG0492  212 VTLKNVktgeeKELEVDGVFVAIGLKP 238
PRK06116 PRK06116
glutathione reductase; Validated
 58-244 5.74e-08

glutathione reductase; Validated


Pssm-ID: 235701 [Multi-domain]  Cd Length: 450  Bit Score: 54.39  E-value: 5.74e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 874572287  58 YRQLLSSRGICWLQDRVINIDLN----NQELTTAASgalqwgdLVLATGTELNDFGVPGvREHACsfrDLNDVAHLRalv 133
Cdd:PRK06116  99 YRNGLENNGVDLIEGFARFVDAHtvevNGERYTADH-------ILIATGGRPSIPDIPG-AEYGI---TSDGFFALE--- 164

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 874572287 134 rELNKRrepdaaVAIIGAGPTGVELACkladMLDG-AARIHLIERGDGILPNSASFNRERAAAALERRDVCLHLNTAVTE 212
Cdd:PRK06116 165 -ELPKR------VAVVGAGYIAVEFAG----VLNGlGSETHLFVRGDAPLRGFDPDIRETLVEEMEKKGIRLHTNAVPKA 233

                        170       180       190
                 ....*....|....*....|....*....|....*..
gi 874572287 213 VH-----SDRVRFKDGTLLPHSGLIWSAGSRPTVPDI 244
Cdd:PRK06116 234 VEknadgSLTLTLEDGETLTVDCLIWAIGREPNTDGL 270
PRK09564 PRK09564
coenzyme A disulfide reductase; Reviewed
 73-216 2.35e-06

coenzyme A disulfide reductase; Reviewed


Pssm-ID: 181958 [Multi-domain]  Cd Length: 444  Bit Score: 49.27  E-value: 2.35e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 874572287  73 RVINIDLNNQELTTAASGALQ-----WGDLVLATGTELNDFGVPGVR-EHACSFRDLNDVAHLRALVRELNKRRepdaaV 146
Cdd:PRK09564  78 EVVKVDAKNKTITVKNLKTGSifndtYDKLMIATGARPIIPPIKNINlENVYTLKSMEDGLALKELLKDEEIKN-----I 152

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 874572287 147 AIIGAGPTGVELAcKLADMLDGAARIhlIERGDGILPNsaSFNRE---RAAAALERRDVCLHLNTAVTEVHSD 216
Cdd:PRK09564 153 VIIGAGFIGLEAV-EAAKHLGKNVRI--IQLEDRILPD--SFDKEitdVMEEELRENGVELHLNEFVKSLIGE 220
Pyr_redox_3 pfam13738
Pyridine nucleotide-disulphide oxidoreductase;
97-224 2.96e-05

Pyridine nucleotide-disulphide oxidoreductase;


Pssm-ID: 404603 [Multi-domain]  Cd Length: 296  Bit Score: 45.29  E-value: 2.96e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 874572287   97 LVLATGtelnDFGVP---GVREHACSFRDLNDVAHLRalvrelnkrrepDAAVAIIGAGPTGVELACKLADMldgAARIH 173
Cdd:pfam13738 122 VIIATG----EFDFPnklGVPELPKHYSYVKDFHPYA------------GQKVVVIGGYNSAVDAALELVRK---GARVT 182

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 874572287  174 LIERGDGILPNSASF-------NRERAAAALERRDVCLHLNTAVTEV----HSDRVRFKDGT 224
Cdd:pfam13738 183 VLYRGSEWEDRDSDPsyslspdTLNRLEELVKNGKIKAHFNAEVKEItevdVSYKVHTEDGR 244
PRK06292 PRK06292
dihydrolipoamide dehydrogenase; Validated
 146-217 2.98e-05

dihydrolipoamide dehydrogenase; Validated


Pssm-ID: 235774 [Multi-domain]  Cd Length: 460  Bit Score: 45.55  E-value: 2.98e-05
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 874572287 146 VAIIGAGPTGVELACKLADMldGaARIHLIERGDGILPNSASFNRERAAAALERRdVCLHLNTAVTEVHSDR 217
Cdd:PRK06292 172 LAVIGGGVIGLELGQALSRL--G-VKVTVFERGDRILPLEDPEVSKQAQKILSKE-FKIKLGAKVTSVEKSG 239
PRK10262 PRK10262
thioredoxin reductase; Provisional
 72-218 3.10e-05

thioredoxin reductase; Provisional


Pssm-ID: 182343 [Multi-domain]  Cd Length: 321  Bit Score: 45.44  E-value: 3.10e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 874572287  72 DRVINIDLNNQELT-TAASGALQWGDLVLATGTELNDFGVPGvrEHACSFRDLNDVAHLRALVRELNKrrepdaaVAIIG 150
Cdd:PRK10262  83 DHINKVDLQNRPFRlTGDSGEYTCDALIIATGASARYLGLPS--EEAFKGRGVSACATCDGFFYRNQK-------VAVIG 153

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 874572287 151 AGPTGVELACKLADMldgAARIHLIERGDGIlpNSASFNRERAAAALERRDVCLHLNTAVTEVHSDRV 218
Cdd:PRK10262 154 GGNTAVEEALYLSNI---ASEVHLIHRRDGF--RAEKILIKRLMDKVENGNIILHTNRTLEEVTGDQM 216
PRK04965 PRK04965
NADH:flavorubredoxin reductase NorW;
73-275 2.98e-04

NADH:flavorubredoxin reductase NorW;


Pssm-ID: 179902 [Multi-domain]  Cd Length: 377  Bit Score: 42.60  E-value: 2.98e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 874572287  73 RVINIDLNNQELTtAASGALQWGDLVLATGTElnDFgVPGVREHACsfrdlndvahlralVRELNKRREPDAA------- 145
Cdd:PRK04965  80 WVTDIDAEAQVVK-SQGNQWQYDKLVLATGAS--AF-VPPIPGREL--------------MLTLNSQQEYRAAetqlrda 141

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 874572287 146 --VAIIGAGPTGVELAcklADMLDGAARIHLIERGDGILPNSASfnrERAAAALERR----DVCLHLNTAV--TEVHSD- 216
Cdd:PRK04965 142 qrVLVVGGGLIGTELA---MDLCRAGKAVTLVDNAASLLASLMP---PEVSSRLQHRltemGVHLLLKSQLqgLEKTDSg 215

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 874572287 217 -RVRFKDGTLLPHSGLIWSAGsrptvpdIRPDPGHAKGP-LNIGQ----DLRL-LGHQHVYVLGDC 275
Cdd:PRK04965 216 iRATLDSGRSIEVDAVIAAAG-------LRPNTALARRAgLAVNRgivvDSYLqTSAPDIYALGDC 274
PRK06370 PRK06370
FAD-containing oxidoreductase;
147-216 5.36e-04

FAD-containing oxidoreductase;


Pssm-ID: 235787 [Multi-domain]  Cd Length: 463  Bit Score: 41.73  E-value: 5.36e-04
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 874572287 147 AIIGAGPTGVELA---CKLadmldgAARIHLIERGDGILPNsasFNRERAAA---ALERRDVCLHLNTAVTEVHSD 216
Cdd:PRK06370 175 VIIGGGYIGLEFAqmfRRF------GSEVTVIERGPRLLPR---EDEDVAAAvreILEREGIDVRLNAECIRVERD 241
PRK09754 PRK09754
phenylpropionate dioxygenase ferredoxin reductase subunit; Provisional
 83-186 1.84e-03

phenylpropionate dioxygenase ferredoxin reductase subunit; Provisional


Pssm-ID: 170080 [Multi-domain]  Cd Length: 396  Bit Score: 39.91  E-value: 1.84e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 874572287  83 ELTTAASGALQWGDLVLATGTELNDFGV-PGVREHACSFRDLNDVAHLRALVRelnkrrePDAAVAIIGAGPTGVELAck 161
Cdd:PRK09754  90 ELVLTNGESWHWDQLFIATGAAARPLPLlDALGERCFTLRHAGDAARLREVLQ-------PERSVVIVGAGTIGLELA-- 160

                         90       100
                 ....*....|....*....|....*
gi 874572287 162 lADMLDGAARIHLIERGDGILPNSA 186
Cdd:PRK09754 161 -ASATQRRCKVTVIELAATVMGRNA 184
YdhS COG4529
Uncharacterized NAD(P)/FAD-binding protein YdhS [General function prediction only];
146-179 5.44e-03

Uncharacterized NAD(P)/FAD-binding protein YdhS [General function prediction only];


Pssm-ID: 443597 [Multi-domain]  Cd Length: 466  Bit Score: 38.78  E-value: 5.44e-03
                         10        20        30
                 ....*....|....*....|....*....|....
gi 874572287 146 VAIIGAGPTGVELACKLADMLDGAARIHLIERGD 179
Cdd:COG4529    8 IAIIGGGASGTALAIHLLRRAPEPLRITLFEPRP 41
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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